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An Apology For Administrative Law In The Contracting State, Mark Seidenfeld

Florida State University Law Review

No abstract provided.

The Pathology Of Rhetoric In Coriolanus, Yvonne Bruce

English Faculty Publications

Coriolanus seems to be a play of action, a dramatized world of mutinous citizens, plotting tribunes, famine, war, and banishment. Yet what really happens in this world? The citizens never realize their mutiny. Brutus and Sicinius never realize their illdefined plot, Coriolanus' consulship is rescinded, the mutual banishment of Coriolanus is undone by his resolve not to make "true wars" against Rome. and the defeat of Aufidius in act one becomes a meaningless victory when Coriolanus is in turn defeated in the final scene of the play. Perhaps it is more accurate to call Coriolanus a play of action, a …

Presence And Television., M. Lombard, R. D. Reich, M. E. Grabe, Cheryl C. Bracken

Communication Faculty Publications

Film and a number of emerging entertainment technologies offer media consumers an illusion of nonmediation known as presence. To investigate the possibility that television can evoke presence, 65 undergraduate students were shown brief examples of rapid point-of-view movement from commercially available videotapes on a television with either a small screen (12 inches [30.5 cm], measured diagonally) or a large screen (46 inches [116.8 cm]). Participants' responses were measured via a questionnaire and a computer-based recording of arousal (electrodermal activity). Viewers of both televisions reported an enjoyable sense of physical movement, excitement, involvement, and a sense of participation. Furthermore, as predicted, …

Condom Distribution-Who Is Benefiting?, Shannon Kelley

e-Vision Journal of Undergraduate Writing

I am confident that if we took the time to ask why so many teenagers are sexually active today, we would discover the solution is not a simple one.

Shannon Kelley _{is a sophomore at James Madison University. She is majoring in Dietetics and wrote this essay in the Spring 2000 semester in GWRIT 102.}

Development Of A High Throughput, Molecular Diagnostic Assay For Predicting Telomerase Activity In Breast Cancer Cell Lines And Tissues, L. Elmore, A. Akalin, L. Gollahon, G. Clarke, M. Grimes, A. Ferreira-Gonzalez, C. Garrett, S. Holt

Massey Comprehensive Cancer Center Publications

Telomerase is a cellular enzyme that helps to provide genomic stability in tumor cells by maintaining the integrity of telomeres. Telomerase is an RNA-dependent DNA polymerase that contains a protein component (hTERT) and an associated RNA (hTR), which is used as a template for telomere repeat addition. Telomerase activity, while not detectable in most normal human somatic cells, is associated with approximately 85% of malignant human cancers overall, including over 90% of breast cancers.

We have optimized a novel, quantitative, high-throughput telomerase activity assay using fluorescently labelled primers and Real Time quantitation via the ABI Prism 7700 (a.k.a., the TaqMan). …

Peginterferon Alfa-2a In Patients With Chronic Hepatitis C And Cirrhosis, E. Jenny Heathcote, Mitchell L. Shiffman, W. Graham E. Cooksley, Geoffrey M. Dusheiko, Samuel S. Lee, Luis Balart, Robert Reindollar, Rajender K. Reddy, Teresa L. Wright, Amy Lin, Joseph Hoffman, Jean De Pamphilis

VCU Health Publications

Background

Chronic hepatitis C virus (HCV) infection in patients with cirrhosis is difficult to treat. In patients with chronic hepatitis C but without cirrhosis, once-weekly administration of interferon modified by the attachment of a 40-kd branched-chain polyethylene glycol moiety (peginterferon alfa-2a) is more efficacious than a regimen of unmodified interferon. We examined the efficacy and safety of peginterferon alfa-2a in patients with HCV-related cirrhosis or bridging fibrosis.

Methods

We randomly assigned 271 patients with cirrhosis or bridging fibrosis to receive subcutaneous treatment with 3 million units of interferon alfa-2a three times weekly (88 patients), 90 µg of peginterferon alfa-2a once …

Adult Daycare: Sharing The Caring, Having A Life, Lory Phillippo Osorio

Case Studies from Age in Action

Objectives

1. Demonstrate the role of adult daycare in community-based services for older adults.

2. Illustrate the diversity of services provided in adult daycare/day health care centers in Virginia.

3. Encourage public policy and funding to expand quality adult daycare in the Commonwealth.

The Aging Woman And Hiv/Aids: Increasing Risk And Incidence, Loretta Brush Normile

Case Studies from Age in Action

Educational Objectives

1. Discuss the increasing incidence of HIV in the aging population.

2. Describe the ways HIV affects the aging person.

3. Identify implications for HIV education and risk assessment of the older population.

Pace: Program Of All-Inclusive Care Of The Elderly, A. Leigh Peyton, Wendy Boggs, Bill Miller, Nancy Allan

Case Studies from Age in Action

Educational Objectives

1. To describe the origin of PACE.

2. To identify essential services provided by the PACE model.

Aging With Cerebral Palsy: A Consumer’S Perspective, Bryan K. Lacy

Case Studies from Age in Action

Educational Objectives

1. To illustrate the necessity of an holistic approach to addressing the changing health care needs of adults with Cerebral Palsy.

2. To show the necessity of dealing honestly and creatively with the intimacy/sexuality concerns of older adults with Cerebral Palsy.

Executive Committee Minutes 1999-2000, Bowling Green State University. Administrative Staff Council

Administrative Staff Council

The records of the Administrative Staff Council (UA-022) are available in print in the Center for Archival Collections.

Meetings With The President 1999-2001, Bowling Green State University. Administrative Staff Council

Administrative Staff Council

The records of the Administrative Staff Council (UA-022) are available in print in the Center for Archival Collections.

Minutes 1999-2000, Bowling Green State University. Administrative Staff Council

Administrative Staff Council

The records of the Administrative Staff Council (UA-022) are available in print in the Center for Archival Collections.

Professional Development Committee 1991-2000, Bowling Green State University. Administrative Staff Council

Administrative Staff Council

The records of the Administrative Staff Council (UA-022) are available in print in the Center for Archival Collections.

Catharine Beecher: America's First Female Philosopher And Theologian, Mark Hall

Faculty Publications - Department of History and Politics

No abstract provided.

Single Audit Report, For The Year Ended June 30, 2000, Tennessee. Department Of Audit, Tennessee. Comptroller Of The Treasury

Single Audit Reports

This report from the Division of State Audit shows the expenditures from the fiscal year.

Town Of Newton, New Hampshire 1999 Annual Report Of The Selectmen, Treasurer And All Other Officers And Committees For The Town Of Newton, New Hampshire Financial Year Ending December 31, 1999., Newton Town Representatives

Newton, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Annual Report Of The Town Officers For The Fiscal Year Ending December 31, 1999 And Of The School District For The Year Ending June 30, 1999., Northwood Town Representatives

Northwood, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Town Of Newmarket Annual Town Report For 2000 For The Fiscal Year Ending June 30, 2000., Newmarket Town Representatives

Newmarket, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Annual Report For The Town Of New Hampton, N.H. For The Year Ending December 31, 1999., New Hampton Town Representatives

New Hampton, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Annual Report For The Town Of Northfield, New Hampshire For The Year Ending December 31, 1999., Northfield Town Representatives

Northfield, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

1999 Annual Report Town Of Nottingham, New Hampshire., Nottingham Town Representatives

Nottingham, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Annual Report Of The Town Officers Nelson, New Hampshire For Year Ending December 31, 1999., Nelson Town Representatives

Nelson, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Thirty Years Of Environmental Protection Law In The Supreme Court, Richard J. Lazarus

Georgetown Law Faculty Lectures and Appearances

It is an honor to present a lecture named after Lloyd Garrison and to be here at Pace Law School. It is especially fitting, of course, that the first Garrison Lecture was presented by Pace's own David Sive. Professor Sive, as we all know, worked closely with Garrison on the celebrated Scenic Hudson litigation. Few legal counsel have been so closely identified with the emergence of the environmental law profession during the past three decades. Indeed, if there were such a thing as a legal thesaurus that linked substantive areas of law with lawyers and one looked up "environ-mental law," …

The Decreased Replicative Capacity Of Simian Immunodeficiency Virus Sivmac239Δnef Is Manifest In Cultures Of Immature Dendritic Cells And T Cells, Davorka Messmer, Ralf Ignatius, Christine Santisteban

Publications

Transmission of simian immunodeficiency virus SIVmac239Δnef (Δnef) to macaques results in attenuated replication of the virus in most animals and ultimately induces protection against challenge with some pathogenic, wild- type SIV strains. It has been difficult, however, to identify a culture system in which the replication of Δnef is severely reduced relative to that of the wild type. We have utilized a primary culture system consisting of blood-derived dendritic cells (DCs) and autologous T cells. When the DCs were fully differentiated or mature, the DC-CD4⁺ T-cell mixtures supported replication of both the parental SIV strain, 239 (the wild type), …

Mature Dendritic Cells Boost Functionally Superior Cd8+ T-Cell In Humans Without Foreign Helper Epitopes, Madhav V. Dhodapkar, Joseph Krasovsky, Ralph M. Steinman, Nina Bhardwaj

Publications

We have recently shown that a single injection of mature, antigen- pulsed, human dendritic cells (DCs) rapidly elicits CD4⁺ and CD8⁺ T-cell immunity in vivo. The DCs were pulsed with 2 foreign proteins, keyhole limpet hemocyanin (KLH) and tetanus toxoid (TT), as well as an HLA A2.1-restricted influenza matrix peptide (MP). Responses to all 3 antigens peaked at 30-90 days after immunization and declined thereafter. To determine if the foreign helper proteins (TT and KLH) were essential for CD8⁺ T-cell responses to the viral peptide, we reinjected 3 of the HLA-2.1 subjects with mature DCs pulsed with …

The Formation Of Immunogenic Major Histocompatibility Complex Class Ii-Peptide Ligands In Lysosomal Compartments Of Dendritic Cells Is Regulated By Inflammatory Stimuli, Kayo Inaba, Shannon J. Turley, Tomonori Iyoda

Publications

During their final differentiation or maturation, dendritic cells (DCs) redistribute their major histocompatibility complex (MHC) class II products from intracellular compartments to the plasma membrane. Using cells arrested in the immature state, we now find that DCs also regulate the initial intracellular formation of immunogenic MHC class II-peptide complexes. Immature DCs internalize the protein antigen, hen egg lysozyme (HEL), into late endosomes and lysosomes rich in MHC class II molecules. There, despite extensive colocalization of HEL protein and MHC class II products, MHC class II-peptide complexes do not form unless the DCs are exposed to inflammatory mediators such as tumor …

Human Cd4+ T Lymphocytes Consistently Respond To The Latent Epstein- Barr Virus Nuclear Antigen Ebna1, Christian Münz, Kara L. Bickham, Marion S. Subklewe

Publications

The Epstein-Barr virus (EBV)-encoded nuclear antigen EBNA1 is critical for the persistence of the viral episome in replicating EBV-transformed human B cells. Therefore, all EBV-induced tumors express this foreign antigen. However, EBNA1 is invisible to CD8⁺ cytotoxic T lymphocytes because its Gly/Ala repeat domain prevents proteasome-dependent processing for presentation on major histocompatibility complex (MHC) class I. We now describe that CD4⁺ T cells from healthy adults are primed to EBNA1. In fact, among latent EBV antigens that stimulate CD4⁺ T cells, EBNA1 is preferentially recognized. We present evidence that the CD4⁺ response may provide a protective …

The Dendritic Cell Receptor For Endocytosis, Dec-205, Can Recycle And Enhance Antigen Presentation Via Major Histocompatibility Complex Class Ii-Positive Lysosomal Compartments, Karsten Mahnke, Ming Guo, Sena J. Lee

Publications

Many receptors for endocytosis recycle into and out of cells through early endosomes. We now find in dendritic cells that the DEC-205 multilectin receptor targets late endosomes or lysosomes rich in major histocompatibility complex class II (MHC II) products, whereas the homologous macrophage mannose receptor (MMR), as expected, is found in more peripheral endosomes. To analyze this finding, the cytosolic tails of DEC-205 and MMR were fused to the external domain of the CD16 Fcγ receptor and studied in stable L cell transfectants. The two cytosolic domains each mediated rapid uptake of human immunoglobulin (Ig)G followed by recycling of intact …

2nd Annual Student Academic Conference: Conference Program & Abstracts Volume Ii, Moorhead State University

Student Academic Conference Abstract Books

Moorhead State University Student Academic Conference abstract book.