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1999

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Housing And Population Health: A Review Of The Literature, Stephen Hwang, Esme Fuller-Thomson, J. David Hurlchanski, Toba Bryant, Youssef Habib, Wendy C. Regoeczi Jan 1999

Housing And Population Health: A Review Of The Literature, Stephen Hwang, Esme Fuller-Thomson, J. David Hurlchanski, Toba Bryant, Youssef Habib, Wendy C. Regoeczi

Sociology & Criminology Faculty Publications

Research into the relationship between housing and health has frequently been narrowly focused, fragmented, and of marginal practical relevance to either housing or health studies. Population health research, in its reference to the importance of the social and physical environment, rarely mentions housing. While it has been recognized for some time that there is a need for the development of a co-ordinated, integrated and cumulative body of housing and health research, there is still very little formal co-ordination between housing policy and population health policy. More attention needs to be paid to measuring the nature and extent to which better …


Dr. Thomas D. Holland Cv, Thomas D. Holland Jan 1999

Dr. Thomas D. Holland Cv, Thomas D. Holland

Forensic Medicine

No abstract provided.


Geriatric Interdisciplinary Team Training, Rita Jablonski, David A. Cifu, Peter A. Boling, Patricia Slattum, A. Leigh Peyton, F. Ellen Netting, Iris A. Parham, Joan B. Wood Jan 1999

Geriatric Interdisciplinary Team Training, Rita Jablonski, David A. Cifu, Peter A. Boling, Patricia Slattum, A. Leigh Peyton, F. Ellen Netting, Iris A. Parham, Joan B. Wood

Case Studies from Age in Action

Educational Objectives

1. To demonstrate the importance of training health care professionals in inter-disciplinary teamwork and geriatric health issues.

2. To increase one’s knowledge of the roles and responsibilities of the various disciplines involved in interdisciplinary teamwork.


Ovulatory And Metabolic Effects Of D-Chiro-Inositol In The Polycystic Ovary Syndrome, John E. Nestler, Daniela J. Jakubowicz , M.D., Paula Reamer , M.A., Ronald D. Gunn , M.S., Geoffrey Allan , Ph. D. Jan 1999

Ovulatory And Metabolic Effects Of D-Chiro-Inositol In The Polycystic Ovary Syndrome, John E. Nestler, Daniela J. Jakubowicz , M.D., Paula Reamer , M.A., Ronald D. Gunn , M.S., Geoffrey Allan , Ph. D.

Obstetrics and Gynecology Publications

BACKGROUND

Women with the polycystic ovary syndrome have insulin resistance and hyperinsulinemia, possibly because of a deficiency of a d-chiro-inositol–containing phosphoglycan that mediates the action of insulin. We hypothesized that the administration of d-chiro-inositol would replenish stores of the mediator and improve insulin sensitivity.

METHODS

We measured steroids in serum and performed oral glucose-tolerance tests before and after the oral administration of 1200 mg of d-chiro-inositol or placebo once daily for six to eight weeks in 44 obese women with the polycystic ovary syndrome. The serum progesterone concentration was measured weekly to monitor for …


Constituent Network 1987-1988 To 1998-1999, Bowling Green State University. Administrative Staff Council Jan 1999

Constituent Network 1987-1988 To 1998-1999, Bowling Green State University. Administrative Staff Council

Administrative Staff Council

The records of the Administrative Staff Council (UA-022) are available in print in the Center for Archival Collections.


Evolution Of Thermotolerance And Variation In The Heat Shock Protein, Hsp70, Robert A. Krebs, Brian R. Bettencourt Jan 1999

Evolution Of Thermotolerance And Variation In The Heat Shock Protein, Hsp70, Robert A. Krebs, Brian R. Bettencourt

Biological, Geological, and Environmental Faculty Publications

Low to moderate levels of stress induce a class of molecular chaperones called heat shock proteins (Hsps), which protect cells, tissues and whole organisms from more severe stress. In higher Eukaryotes, Hsp70 is one of the principle heat-induced chaperones. This response is general, and how much Hsp70 an animal produces correlates with the level of stress to which it is exposed. Nonetheless, definitively linking high Hsp70 expression as an adaptation to stress tolerance is problematic, because organisms and cells respond to stress in many ways. By molecular manipulation of Hsp70 in one animal group, Drosophila, differences in hsp70 copy number …


The Tribune, No. 58, May 1999 Jan 1999

The Tribune, No. 58, May 1999

Mildred E. Persinger Papers

No abstract provided.


Rapid Generation Of Broad T-Cell Immunity In Humans After A Single Injection Of Mature Dendritic Cells, Madhav V. Dhodapkar, Ralph M. Steinman, Mark Sapp Jan 1999

Rapid Generation Of Broad T-Cell Immunity In Humans After A Single Injection Of Mature Dendritic Cells, Madhav V. Dhodapkar, Ralph M. Steinman, Mark Sapp

Publications

Dendritic cells (DCs) are potent antigen-presenting cells that initiate protective T-cell immunity in mice. To study the immunogenicity of DCs in humans, we injected 9 healthy subjects subcutaneously with a control injection of autologous monocyte-derived, mature DCs, followed 4-6 weeks later by DCs pulsed with keyhole limpet hemocyanin (KLH), HLA-A*0201- positive restricted influenza matrix peptide (MP), and tetanus toxoid (TT). Four more subjects received these antigens without DCs. Injection of unpulsed DCs, or antigens alone, failed to immunize. Priming of CD4+ T cells to KLH was observed in all 9 subjects injected with KLH-pulsed DCs, and boosting of TT-specific …


Vaccination With Mage-3a1 Peptide-Pulsed Nature, Monocyte-Derived Dendritic Cells Expands Specific Cytotoxic T Cells And Induces Regression Of Some Metastases In Advanced Stage Iv Melanoma, Beatrice Thurner, Ina Haendle, Claudia Röder Jan 1999

Vaccination With Mage-3a1 Peptide-Pulsed Nature, Monocyte-Derived Dendritic Cells Expands Specific Cytotoxic T Cells And Induces Regression Of Some Metastases In Advanced Stage Iv Melanoma, Beatrice Thurner, Ina Haendle, Claudia Röder

Publications

Dendritic cells (DCs) are considered to be promising adjuvants for inducing immunity to cancer. We used mature, monocyte-derived DCs to elicit resistance to malignant melanoma. The DCs were pulsed with Mage-3A1 tumor peptide and a recall antigens, tetanus toxoid or tuberculin. 11 far advanced stage IV melanoma patients, who were progressive despite standard chemotherapy, received five DC vaccinations at 14-d intervals. The first three vaccinations were administered into the skin, 3 x 106 DCs each subcutaneously and intradermally, followed by two intravenous injections of 6 x 106 and 12 x 106 DCs, respectively. Only minor (less than …


Virus Replication Begins In Dendritic Cells During The Transmission Of Hiv-1 From Mature Dendritic Cells To T Cells, Angela Granelli-Piperno, Victoria Finkel, Elena Delgado, Ralph M. Steinman Jan 1999

Virus Replication Begins In Dendritic Cells During The Transmission Of Hiv-1 From Mature Dendritic Cells To T Cells, Angela Granelli-Piperno, Victoria Finkel, Elena Delgado, Ralph M. Steinman

Publications

Background: To initiate immunity, dendritic cells (DCs) capture antigens or viruses at body surfaces, undergo maturation to express T-cell costimulatory molecules, and then migrate to lymphoid organs. DCs at body surfaces can capture human immunodeficiency virus 1 (HIV-1), but mature DCs do not support replication of the virus unless T cells are added. The initial site for HIV-1 replication remains unknown and it is unclear whether replication can take place in DCs or whether the virus must first be transmitted from DCs to T cells. Results: We generated mature DCs from monocyte precursors. Upon infection with HIV-1, reverse transcription was …


Bridging The Disciplines: Student Academic Conference, Moorhead State University Jan 1999

Bridging The Disciplines: Student Academic Conference, Moorhead State University

Student Academic Conference Abstract Books

Moorhead State University Student Academic Conference abstract book.


Winter 1999, Seattle University Jan 1999

Winter 1999, Seattle University

Seattle University News (Sun)

No abstract provided.


1999-2000 Bulletin Of Information - Undergraduate, Seattle University Jan 1999

1999-2000 Bulletin Of Information - Undergraduate, Seattle University

Bulletin of Information

No abstract provided.


Aquilegia, Vol. 23 No. 1, January-February 1999: Newsletter Of The Colorado Native Plant Society, Leo P. Bruederle, Rick Brune, Hilary Davis, Sally White, Elizabeth Anderson, Carolyn Crawford, Nicola Ripley, Gary Bentrup, Kris Meiring, Janet L. Wingate, Sue Galatowitsch Jan 1999

Aquilegia, Vol. 23 No. 1, January-February 1999: Newsletter Of The Colorado Native Plant Society, Leo P. Bruederle, Rick Brune, Hilary Davis, Sally White, Elizabeth Anderson, Carolyn Crawford, Nicola Ripley, Gary Bentrup, Kris Meiring, Janet L. Wingate, Sue Galatowitsch

Aquilegia - Colorado Native Plant Society

No abstract provided.


Natural History Of The Marbled Salamander, Ambystoma Opacum (Gravenhorst), In West Virginia, With Special Notes On Reproduction And Larval Development, Jason J. Watkins Jan 1999

Natural History Of The Marbled Salamander, Ambystoma Opacum (Gravenhorst), In West Virginia, With Special Notes On Reproduction And Larval Development, Jason J. Watkins

Theses, Dissertations and Capstones

This study observed a population of Ambystoma opacum in Kanawha State Forest, Kanawha County, five miles south of Charleston, West Virginia. Data were collected from September 1995 to November 1997. Reproductive biology and salamander development were examined. Predation of A. opacum and potential predators were also noted. Like other species in the genus Ambystoma, adult A. opacum are mostly fossorial and rarely seen above ground outside of the breeding season. During the breeding season, adults make their way to the breeding pools. Males ventured to the breeding pool first in early September and ranged in size from 49 to 75mm …


The Cardiovascular And Metabolic Adaptations To Iso-Caloric Moderate Intensity And High Intensity Exercise, Summerson Desmond Jan 1999

The Cardiovascular And Metabolic Adaptations To Iso-Caloric Moderate Intensity And High Intensity Exercise, Summerson Desmond

Theses, Dissertations and Capstones

Cardiovascular disease is the leading cause of death in the industrialized nations, and accounts for 1 million deaths in the United States each year (McArdle, Katch & Katch, 1991). One of the major risk factors for cardiovascular disease is physical inactivity, which is a behavioral modified risk factor. Physical inactivity plagues 59% of the people in the United States (ACSM Resource Manual, 1998). Physical inactivity often leads to obesity, diabetes, hypertension and hypercholemia, and places sedentary individuals at more risk for cardiovascular disease (CVD), or coronary heart disease (CHD). The question which remains unclear is the quantity and quality of …


The Acquisition And Quantitative Analysis Of Digitally Generated Fourier Transforms Resulting From The Physiognomy Of Various Tree And Shrub Species, Alicia Eldridge-Spears Jan 1999

The Acquisition And Quantitative Analysis Of Digitally Generated Fourier Transforms Resulting From The Physiognomy Of Various Tree And Shrub Species, Alicia Eldridge-Spears

Theses, Dissertations and Capstones

An optical Fourier transform represents the interference of wavefronts produced as light passes through multiple slits. Theoretically, any image containing periodic structure causes diffraction. The cellular arrangement of a plant leaf and the regularity in venation are ideal conditions for diffracting light. As light passes through columns of cells, its path is altered according to the distance and orientation present.

A photograph or slide of a leaf or the leaf itself may be used to produce a diffraction pattern by either optical or digital means. Optically, a laser beam directed through a slide is refracted by a converging lens and …


The Relationship Between Ohio River Bass Tournament Success Rates, Forage Fish Abundance And Environmental Conditions, Jeffrey V. Ginger Jan 1999

The Relationship Between Ohio River Bass Tournament Success Rates, Forage Fish Abundance And Environmental Conditions, Jeffrey V. Ginger

Theses, Dissertations and Capstones

Due to increasing pressure from Ohio River bass anglers with regard to decreasing catch rates in 1981,1990, and 1997, the West Virginia Division of Natural Resources (WVDNR) initiated a study of black bass populations. The Ohio River Valley Water Sanitation Commission (ORSANCO), in conjunction with state and Federal agencies, has collected population data on Ohio River fishes at lock chambers and has measured various water quality parameters since 1957. That data coupled with Ohio River bass tournament data collected by the DNR since 1975 and other fishery data sets provided a historic look into the variability of angler success. These …


A New Model For Predicting Probabilities Of Viable Pregnancy And Multiple Gestations For I̲N̲ V̲I̲T̲R̲O̲ Fertilization, Ray Vernon Haning Jr. Jan 1999

A New Model For Predicting Probabilities Of Viable Pregnancy And Multiple Gestations For I̲N̲ V̲I̲T̲R̲O̲ Fertilization, Ray Vernon Haning Jr.

Theses, Dissertations and Capstones

In vitro fertilization (IVF) can be viewed as high stakes gambling with more than one winning outcome and more than one outcome leading to failure. Knowing the odds of successful outcomes, the odds of outcomes leading to failure, and the various costs is a tremendous asset in any form of gambling. Four important variables have been reported to affect pregnancy rates in IVF programs: age of patient, number of unsuccessful prior attempts, embryo morphology, and number of embryos transferred.

While it is desirable to optimize pregnancy rates, such optimization may often result in a high incidence of multiple gestation. Data …


Treatment For The Homeless Mentally Ill, Joyel Harless Jan 1999

Treatment For The Homeless Mentally Ill, Joyel Harless

Theses, Dissertations and Capstones

The effect of treatment on the homeless mentally ill was explored. Seventeen homeless individuals were screened with questionnaires to determine anxiety and depression (Krug, Laughlin, Scheiner, & Catell, 1976). One group included diagnosed mentally ill subjects, the other were non-diagnosed individuals. Both groups were tested upon admittance to either a treatment facility for homeless mentally ill persons or a community homeless shelter, respectively. They were again screened prior to discharge of either facility. Statistically, a rather significant difference was noted in the decrease of the diagnosed group’s anxiety level upon discharge. A similar, but less significant, statistical difference was also …


Ecology And Population Demography Of The Hellbender, Cryptobranchus Alleganiensis, In West Virginia, W. Jeffrey Humphries Jan 1999

Ecology And Population Demography Of The Hellbender, Cryptobranchus Alleganiensis, In West Virginia, W. Jeffrey Humphries

Theses, Dissertations and Capstones

Using mark-recapture, I studied the population demography and habitat use of the hellbender, Cryptobranchus alleganiensis, in the West Fork of the Greenbrier River, Pocahontas County, West Virginia. Eighteen nocturnal surveys were conducted between April and October, 1998, during which 29 hellbenders were implanted with permanent tags. Male to female sex ratio was 1.06:1. Hellbenders were sexually dimorphic, as females were significantly longer and heavier than males. Total lengths for all captured animals ranged from 29.5 - 56.5 cm and mass ranged from 150.0 - 905.8 g. Seasonal linear movements for 12 individuals ranged from 0.8 - 70.2 m (mean …


Food Habits Of Salmo Trutta And Salvelinus Fontinalis (Pisces: Salmonidae) In Relation To Seasonal Changes And Mitigative Liming Effects In Dogway Fork Of The Cranberry River, West Virginia., Jason A. Morgan Jan 1999

Food Habits Of Salmo Trutta And Salvelinus Fontinalis (Pisces: Salmonidae) In Relation To Seasonal Changes And Mitigative Liming Effects In Dogway Fork Of The Cranberry River, West Virginia., Jason A. Morgan

Theses, Dissertations and Capstones

Dogway Fork, a tributary of the Cranberry River in West Virginia, is acidic due to acid precipitation and poorly buffered soils. This study is part of a long-term investigation involving the effects of continuous limestone neutralization on the fishes and benthos of an acid stream. Prior to treatment in 1988, the stream had a pH of 4.5 and there were no fish present. Since treatment began, the pH of the stream has risen to 6.8. Nine species of fish have been collected and six species have reproduced following the improvement in water quality. Densities of specific acid-sensitive benthic macroinvertebrates have …


Preparation Of N-(Haloaryl) Succinimides, Okey Noe Ii Jan 1999

Preparation Of N-(Haloaryl) Succinimides, Okey Noe Ii

Theses, Dissertations and Capstones

N-(3,5-Dichloro-4-fluorophenyl)succinimide (NDCFPS) and N-(3,5-dichloro-4- pyridyl)succinimide (NDPyS) were synthesized using procedures employed previously for N-(3,5-dichIorophenyl)succinimide (NDPS). However, NDPyS was not formed cleanly: extraction from by-products was necessary and purification by column chromatograpy was required. Several potential alternative routes to NDPyS were investigated without success.

Both compounds were administered to male Fischer 344 rats to assess nephrotoxic potential. NDCFPS, contrary to expectations, was non-nephrotoxic. Preliminary results indicate that NDPyS is also non-nephrotoxic.


Feeding Niches Of Forest Salamanders: Indirect Effects Of Gypsy Moth Pesticides On Prey Selection And Potential Overlap Between Adults Of Six Species, Sandra Raimondo Jan 1999

Feeding Niches Of Forest Salamanders: Indirect Effects Of Gypsy Moth Pesticides On Prey Selection And Potential Overlap Between Adults Of Six Species, Sandra Raimondo

Theses, Dissertations and Capstones

Amphibian declines and deformities are indictors of pollution and other environmental impacts. Pesticides, such as Bacillus thuringiensis var. kurstaki (Bt), may produce non-target effects on salamanders by impacting their food supply, ultimately resulting in population declines. Salamanders were used as an assessment tool of pesticide impacts before populations decline. Diet analysis determined if Bt affected food consumption of two salamander species (Desmognathus ochrophaeus and P. cinereus). Nine plots in the Monongahela National Forest, West Virginia were used in this study. Three plots were sprayed with Bt in 1997 and 1998, three were sprayed with a gypsy moth …


Patient/Physician Communication: A Comprehensive Review Of The Medical Literature, 1989 To 1998, David L. Rodgers Jan 1999

Patient/Physician Communication: A Comprehensive Review Of The Medical Literature, 1989 To 1998, David L. Rodgers

Theses, Dissertations and Capstones

Patient/physician communication is recognized as an important topic in the medical literature. The subject has steadily been increasing in the frequency of reporting in the literature. After a comprehensive review of this literature, positive patient/physician communication has been clearly linked to improved patient and physician satisfaction, increased compliance with treatments, improved health outcomes, decreased risks of litigation, as well as creating a more caring, empathetic relationship. Yet despite these advantages, patient/physician communication does not occupy a significant portion of the medical school curriculum and styles of physician communication that promote positive patient/physician communication are not readily used. This study examines …


Distribution Of The Sucker Family (Pisces: Catostomidae) In The Ohio River, Tara L. Rose Jan 1999

Distribution Of The Sucker Family (Pisces: Catostomidae) In The Ohio River, Tara L. Rose

Theses, Dissertations and Capstones

The family Catostomidae represents a major component of the fish fauna in the Ohio River. Because of their abundance, large biomass, and susceptibility to environmentally-induced anomalies, suckers are expected to significantly influence the Ohio River Fish Index (ORFIn), a biological index being developed by the Ohio River Valley Water Sanitation Commission (ORSANCO) for large river systems. To correctly interpret information obtained from ORFIn, the impact of suckers upon the index must be thoroughly understood, including relative importance and uneven spatial distribution of Ohio River suckers. In this study, suckers represented 7.1 percent of the total fish captured and 36.6 percent …


Ecology And Natural History Of Rana Clamitans Melanota In West Virginia, Alison M. Rogers Jan 1999

Ecology And Natural History Of Rana Clamitans Melanota In West Virginia, Alison M. Rogers

Theses, Dissertations and Capstones

Fourteen study sites were sampled with aquatic funnel traps and D-frame net sweeps in the plateau and mountain region of West Virginia to determine differences in larval period. Larval stage class abundance and larval total length and mass measurements were recorded from February to December 1997. Larval stage classes 25 and 26, the first free living stages, were absent from the plateau region from February to April, but were present in the mountain region. Pre-transformation larval stages, 40 through 44, were found from May through October, and peaked in July. Significant relationships were found with simple linear regression analysis between …


Interaction Of Laminin Beta2 With Eps8 And Desmin In Muscle Cells, Luke Xueliang Cui Jan 1999

Interaction Of Laminin Beta2 With Eps8 And Desmin In Muscle Cells, Luke Xueliang Cui

Theses, Dissertations and Capstones

Laminin β2 is localized to the synaptic basal lamina (BL) in muscle and glomerular BL in kidney. To find interacting proteins, a mouse kidney cDNA library was screened with domain I of rat laminin β2 using the yeast two-hybrid system. Fifteen positive clones were found. The DNA sequence of three each of these clones corresponded to the phosphoprotein Eps8 (epidermal growth factor receptor pathway substrate clone 8, which is tyrosine phosphorylated after EGF stimulation) and the intermediate filament (IF) protein keratin. To determine if this interaction occurred in muscle cells, C2 cells transfected with the rat …


The Role Of Retinoids And Protein Kinase C In Vascular Smooth Muscle Cell Proliferation And Function, Shaoshan Wang Jan 1999

The Role Of Retinoids And Protein Kinase C In Vascular Smooth Muscle Cell Proliferation And Function, Shaoshan Wang

Theses, Dissertations and Capstones

The structural and functional changes in the arterial wall of humans and animals accompany the development of hypertension and atherosclerosis. Hence, great interest exists in the mechanisms that govern vascular smooth muscle cell contraction and proliferation. Rat aortic rings maintained in organ culture show a significant loss of contractility; whereas, vascular smooth muscle cells in culture quickly dedifferentiate into a secretory phenotype with a marked capacity for proliferation. The addition of all-trans retinoic acid (RA) and retinol to the plasma-containing medium preserved the contractile response of cultured vessels. Removal of endothelium prior to culture abolished these effects. All-trans retinoic acid …


A Medicinal Plant Survey In Marketplaces Of Ecuador, Pamela Bailey Jan 1999

A Medicinal Plant Survey In Marketplaces Of Ecuador, Pamela Bailey

Theses, Dissertations and Capstones

A medicinal herb survey was conducted in ten major marketplaces in Andean and coastal communities of Ecuador. Collections were made during the summer of 1997. Four plant collections from each market were pressed, dried, identified, and the medicinal information for each plant was recorded. Photographs of fresh plants, market vendors and the marketplaces were taken.

Fifty three families were represented in the 112 species collected. Forty-two species (37%) were introduced to Ecuador while seventy species (63%) were native to Ecuador. Plant taxa were grouped into 22 categories of medicinal usage. The most common 3 uses were: 1. General tonic and …