Alcohol Withdrawal Management Practices And Prevention Of Escalation Events In Hospitalized Adults, Danielle Logan

Walden Dissertations and Doctoral Studies

This Doctor of Nursing Practice project was an organizational process evaluation examining alcohol withdrawal management among hospitalized adults. Alcohol withdrawal can cause severe agitation, seizures, delirium, behavioral emergencies, transfers, and prolonged hospitalization, making early recognition and evidence-based management essential to patient safety. The practice-focused question examined whether hospitalized adults experiencing alcohol withdrawal were assessed and treated proactively based on risk factors and clinical presentation or reactively after symptom escalation, and whether management practices contributed to Code Green activation and higher-level-of-care transfers. The purpose was to identify practice gaps and develop evidence-based recommendations to improve safety and consistency of care. A …

African American Mother Counselors' Lived Experiences During The Dual Pandemics Of Covid-19 And Structural Racism, Shanti Jones

Walden Dissertations and Doctoral Studies

The problem addressed in this study was that the dual pandemics of COVID-19 and structural racism in 2020 created compounded personal and professional stressors for African American mothers who are professional counselors, yet little was known about how they appraised these stressors and selected coping strategies. The purpose of this hermeneutic phenomenological study was to describe what it means to be an African American mother and professional counselor making decisions about coping strategies to manage personal and professional stressors during the dual pandemics of COVID-19 and structural racism in 2020. Guided by Heideggerian hermeneutic phenomenology and informed by the Transactional …

Development Of A Proposal For An Occupational Safety And Wellness Program, Lodie Rogers

Walden Dissertations and Doctoral Studies

This Doctor of Nursing Practice (DNP) evidence-based practice project was a quality improvement initiative focused on developing and implementing an occupational safety and wellness program (OSWP) in an industrial organization. The practice problem was the absence of a formal, standardized program for injury prevention, near-miss reporting, hazard identification, employee wellness, safety education, and leadership accountability. Evidence from scholarly databases, Occupational Safety and Health Administration (OSHA) reports, organizational safety data, incident reports, near-miss documentation, and compliance measures supported the project. I examined how a 10-week OSWP can reduce employee incidents, improve safety culture, decrease injuries, increase engagement, and sustain wellness practices. …

Hiring Out-Of-Field Teachers In Urban Title I Schools In Georgia, Lakeshia Pruitt Dixon

Walden Dissertations and Doctoral Studies

Urban Title I schools commonly experience teacher shortages, prompting principals to hire teachers to teach content areas for which they are not certified. The problem addressed in this study was that 8% of the teachers within a large urban school district in Georgia were teaching out-of-field. Guided by Elmore’s conceptual framework of knowledge, skills, and dispositions, the purpose of this basic qualitative study was to explore the factors contributing to principals’ decisions to recommend hiring out-of-field teachers in urban Title I schools in Georgia and to examine the support available for those teachers to meet certification requirements. Semistructured interviews were …

Staff Education About Prescribing Glucagon-Like Peptide-1s (Glp1s), Deenis Garcia

Walden Dissertations and Doctoral Studies

Obesity is a growing health concern that affects many people. In recent years, the use of glucagon-like peptide-1 (GLP1s) has become increasingly popular to combat obesity. The use of GLP1s has shown successful outcomes, yet there are inconsistencies when prescribing the medication for weight loss. The practice problem identified at the organization was the lack of consistent and evidence-based guidance for providers to utilize when prescribing GLP1s for weight loss. The practice-focused question was to determine whether education on structured guidance tools for clinical staff who prescribe GLP1 medications improves their knowledge and intent to use these tools when prescribing …

The Study Of Hydrophobic Biomolecules With Matrix Assisted Laser Desorption Ionization Mass Spectrometry And Atomic Force Microscopy, Brandy L. Perkins

LSU Doctoral Dissertations

Abstract

Matrix assisted laser desorption ionization (MALDI) mass spectrometry (MS) can be used to obtain localization and chemical information of hydrophobic biomolecules on tissue samples.  A technique has been developed to modify a standard MALDI matrix that improves the selectivity for hydrophobic biomolecules on the tissue sample. The modification involves the use of a Group of Uniform Materials Based on Organic Salts (GUMBOS). GUMBOS are ionic liquids (IL) that are bulky organic ions with a counter ion that can be changed for tuning.  They are more stable than traditional matrices under vacuum.  Unlike traditional IL’s, the GUMBOS melting point ranges …

The Student Performer's Guide To Creating A Consortium, Jaycee Swan

LSU Doctoral Dissertations

Among advanced musicians who advocate for increasing diversity in classically oriented repertoire, music commissioning is a common practice. Funding a composer to write original music, however, seems out of reach for student musicians or those without the financial means and know-how. A more affordable and therefore accessible alternative to the stand-alone commission is the consortium-based commission for new music. In this lecture portion of a “lecture-recital with written document,” I (a) document my experience in spearheading a new music consortium and, from that experience, (b) present a guide for facilitating a new music consortium.

The project was the impetus for …

Maleficia's Magic: Witchcraft, Race, And The Legacy Of Afro-Mexican Women And Identity In Colonial New Spain, Siobhan K. Arechavala

Honors Theses

This thesis examines the disproportionate prosecution of mulatta and Black women by the Mexican Inquisition in the sixteenth and seventeenth centuries and argues that this pattern was not incidental to Spanish colonialism but central to it. Drawing primarily on inquisitorial trial records from the Huntington Library’s Mexican Inquisition Papers and the Archivo General de la Nación’s Ramo Inquisición, alongside period treatises and secondary scholarship on witchcraft, caste, and Afro-Mexican history, the study traces how limpieza de sangre, Christian demonology, and colonial racial hierarchy combined to position African-descended women as embodiments of the disorder colonial elites feared most. The first chapter …

From Words To Form: Disability In Contemporary Italian And Italian American Literature, Arianna Salomon

Electronic Theses and Dissertations

This dissertation traces nearly fifty years of representations of disability, understood as a cultural category, from the late 1970s to the early 2020s, in two interconnected traditions: Italian and Italian American literature. In particular, it explores how disability reshapes the act and aesthetics of writing in contemporary Italian and Italian American novels and memoirs. Given the field’s relative newness, the substantial groundwork still required, and the many connections between literature and disability, this dissertation uses nine case studies with a balanced pairing of Italian and Italian American works in each chapter: Carmelo Samonà’s Fratelli (1978) and Tina De Rosa’s Paper …

Discursive Consciousness And Pedagogical Reasoning Within Teacher Collaborative Inquiry In Rural Mexico, Nelly Yllen Charles Martinez

Theses and Dissertations

This study examines teacher collaborative learning within Matemáticas Equitativas (MATEQ), a school-based professional learning model designed to support equitable mathematics instruction through collaborative inquiry and peer observation. Drawing on Anthony Giddens' structure-agency theory, this research adopts an interpretive qualitative case study with discourse-oriented analysis to examine teachers' pedagogical reasoning by looking at manifestations of discursive consciousness--defined as the capacity to articulate and rationalize one's actions in discourse--during collaborative meetings. Findings show that both the interactional structures and collaborative resources embedded in MATEQ--in particular peer facilitated uses of observation rubrics--mediated teachers' discursive consciousness, strengthening the pedagogical reasoning shared within collaborative inquiry. …

Selective Factors Impacting Charter High School Enrollment, Nathan Marshall

Theses and Dissertations

This study examined factors influencing high school choice among Utah families, comparing parent priorities between charter and traditional public high schools. Using one-way ANOVA with Tukey honestly significant difference (HSD) post hoc comparisons, parental priorities were analyzed across personal, school community, and academic factors. Parents choosing traditional public high schools rated personal and school community factors significantly higher, emphasizing relationships and school climate, while charter high school parents rated academic factors significantly higher, favoring rigor and instructional quality. Charter parents' priorities were not uniform, however, but varied significantly by school model, suggesting that the charter-versus-traditional divide masks meaningful differences within …

Environmental Exposure Risk Education To Enhance Chronic Kidney Disease Prevention And Screening For Nurse Practitioners, Kelsea J. Carrier

Doctor of Nursing Practice Scholarly Projects

Chronic kidney disease (CKD) affects approximately 36 million adults in the United States, with nearly 90% of individuals unaware of their diagnosis until advanced stages. While diabetes and hypertension remain the primary causes, increasing evidence highlights environmental exposures as significant and underrecognized contributors to CKD onset and progression. Exposures such as heavy metals, per- and polyfluoroalkyl substances (PFAS), air and water pollution, microplastics, and heat exposure have been linked to impaired renal function. Despite this growing body of evidence, environmental health content remains limited in nursing education, resulting in gaps in environmental health literacy (EHL) among nurse practitioners (NPs) and …

Strategies Used By Silicon Valley Technology Leaders To Advance Latinx Employees Into Leadership Roles To Increase Firm Productivity, Elizabeth A. Garcia

Walden Dissertations and Doctoral Studies

The underrepresentation of Latinx professionals in leadership roles remains a challenge for technology leaders. Leaders who lack effective leadership development strategies for Latinx employees may experience reduced innovation, lower productivity, and decreased organizational competitiveness. Grounded in the resource-based view, the purpose of this qualitative pragmatic inquiry research project was to identify and explore effective strategies used by Silicon Valley technology leaders to advance Latinx employees into leadership roles to increase firm productivity. Participants were 10 technology leaders with experience implementing strategies to hire, develop, and promote Latinx talent. Data were collected through semistructured interviews, public organizational documents, and industry publications. …

Bridging Intelligent Optimization And Knowledge-Based Planning: A Retrospective Evaluation Of Ioe And Rapidplan Models For Ethos Lung Adaptive Radiotherapy, Anna Katherine Robbins

Masters Projects

Adaptive radiotherapy (ART) and knowledge-based planning (KBP) have independently improved treatment planning quality and efficiency; however, limited evidence exists regarding their combined use within the Varian Ethos planning system. This retrospective study evaluated whether an institution-specific Ethos-trained RapidPlan model improved dosimetric plan quality compared with Intelligent Optimization Engine (IOE) optimization alone and a publicly available Eclipse-trained RapidPlan model for right-sided non-small cell lung cancer. Ten patients previously treated with adaptive radiotherapy were replanned using three planning approaches: IOE optimization alone, IOE with a generic RapidPlan model, and IOE with an institutional Ethos-trained RapidPlan model. Target coverage, homogeneity, and organ-at-risk (OAR) …

A Data-Driven Framework For Mitigating Breast Cancer Overdiagnosis: From Estimation To Risk-Adjusted Computer-Aided Diagnosis, William M. Brown Jr.

LSU Doctoral Dissertations

In Computer-Aided Diagnosis (CAD) of cancer, standard cost metrics (false-positives and false-negatives) fundamentally fail to account for overdiagnosis. Overdiagnosis is a critical scenario where a disease is correctly detected (true-positive) but is biologically indolent and would never have caused the patient harm or symptoms. While widely recognized in the medical community as a major healthcare crisis driving stressful and invasive overtreatment, overdiagnosis remains severely under-researched within computer science and engineering. This dissertation addresses this interdisciplinary gap by defining the three key computational challenges of overdiagnosis: (i) accurate estimation, (ii) harm quantification, and (iii) algorithmic mitigation. To overcome the estimation challenge, …

Analysis Of Flood Modeling For The Replication Of An Extreme Rainfall Event In South Florida, Lusnel Fritznel Ferdinand

Electronic Theses and Dissertations

Flooding is the most common natural disaster in the United States, and trends show an increase in flood risk for the foreseeable future. Florida averages 45 flood disasters per year, at an annual cost of $86 million. Communities in Florida are susceptible to a variety of flood-inducing sources, including tropical cyclones, extreme rainfall, and rising sea levels, which can impact the tourism industry and the economic well-being of residents. The first objective of the thesis was to use flood modeling to replicate the extreme rainfall event that caused heavy flooding in Broward County, Florida, from April 12-13, 2023. A commercial …

Comparative Performance Evaluation Of A Gpu-Accelerated Watershed Model For Flood Inundation Mapping, Maliha Ali

Electronic Theses and Dissertations

This study evaluates PyWMP (Python-based Watershed Modeling and Planning), which is a flood modeling framework developed by the Center for Water Resiliency and Risk Reduction (CWR3) at Florida Atlantic University (FAU). The framework includes a 2D Rain-on-Mesh (ROM) solver, which is an explicit finite-volume shallow-water equation model. PyWMP is compared against HEC-RAS 2D and Flood Modeller for their rain-on-grid capabilities for watershed-scale flood inundation mapping under three design storm scenarios. The performance of PyWMP was evaluated using both quantitative and spatial metrics. Mean absolute error values showed that the average depth difference between each model is under 1 foot. Percent …

Modeling Nonequilibrium Community Dynamics Of Bivalves In The Indian River Lagoon, Jada Lee Brown

Electronic Theses and Dissertations

Benthic infaunal communities are widely-used indicators for assessing estuarine health, especially in systems that experience frequent disturbances and hydrological fluctuations. However, using benthic infauna to predict ecosystem responses to future disturbances remains a challenge. The Indian River Lagoon (IRL), spanning 40% of Florida's east coast, is a prime example of a complex estuary that has experienced decades of hydrological alterations leading to reduced water quality, sediment composition, and biodiversity. To assess benthic bivalve community dynamics in response to disturbances, an emerging Empirical Dynamic Modeling (EDM) approach was applied to a large test dataset comprising 17 years of benthic bivalve abundances …

Predictive Modeling Of Readmission, Mortality, And Resource Utilization After Surgical And Transcatheter Aortic Valve Replacement, Raymond J. Martin

LSU Master's Theses

Aortic stenosis is the most prevalent valvular heart disease in North America. Its definitive treatments—surgical aortic valve replacement (SAVR) and transcatheter aortic valve replacement (TAVR)—carry a substantial burden of unplanned hospital readmission, which worsens patient outcomes, strains hospital capacity, and creates financial risk under value-based payment programs. Prior predictive work has largely focused on binary classification of 30-day readmission after TAVR. Such studies typically report predictor effects as odds or hazard ratios without validating patient-level probabilities, and neglect both the timing of readmission and the resources it consumes. To address these gaps, this thesis develops and empirically validates a unified, …

From Anaerobic Digesters To The Human Gut: Ecological Responses Of Microbiomes To Environmental And Biological Perturbations, Maliea Annholden Nipko

Theses and Dissertations

Microbial communities regulate essential ecological and metabolic processes across both engineered and host-associated ecosystems. Although these systems differ substantially in composition and function, they are governed by common ecological principles including community succession, resilience, species interactions, and responses to environmental and biological perturbations. This dissertation investigates how perturbations influence microbiome structure, function, and stability through three complementary studies spanning anaerobic digestion and the human gut microbiome. First, the effects of an extremophilic biological pretreatment using Caldicellulosiruptor bescii were evaluated in industrial-scale anaerobic digesters treating dairy manure. High- temperature pretreatment substantially altered microbial community composition, with bacterial populations remaining metabolically active …

Buddy Up: An Interaction Design Project For Supporting Task Initiation And Academic Progress Through Peer Accountability Among University Students, Ruijun Li

Theses

Academic procrastination is a common challenge among university students. Although students often understand what they need to do and when their work is due, they may still have difficulty starting tasks, maintaining progress, and avoiding digital distractions. Many existing productivity tools depend on individual self-discipline and provide limited social support. My thesis explores interaction methods that use peer accountability to help university students begin academic work and maintain consistent progress. Buddy Up aims to turn academic work from an isolated activity into a voluntary and mutually supportive accountability experience.

Pixel Weave: Explore The Craft, Share The Story, Janki Akbari

Theses

Traditional craft practices are often preserved as finished objects rather than experienced as active systems of knowledge. As a result, the techniques, visual logic, and cultural meaning behind these crafts become less accessible to broader audience. Pixel Weave addresses this challenge by translating the double ikat (a premium, highly complex weaving technique in which both the warp (vertical) and weft (horizontal) yarns are individually resist-dyed to a preplanned pattern before being placed on the loom, so that the design only fully emerges once the two dyed yarn sets are woven together) weaving logic of Patan Patola, a centuries old textile …

Temporal Dynamics Of Sleep Value: How Momentary States And Individual Differences Shape The Valuation Of Sleep, Brandon Pattillo

Undergraduate Honors Theses

Objectives Sleep value is the relative worth individuals place on sleep. Although previous work has validated trait-level measures of sleep value, little is known about the valuation process that determines sleep’s value over time. This study examined hourly fluctuations in sleep value and identified predictors of these changes.

Methods Ninety undergraduates completed baseline questionnaires assessing demographic, sleep, and health variables, including the Pittsburgh Sleep Quality Index (PSQI), Values Inventory (VI), and Monetary Sleep Value Questionnaire (MSVQ). Participants completed hourly 24-hour surveys assessing activity, activity value/pleasure, sleepiness, sleep ability, sleep/wake desires and intentions, and willingness-to-pay (WTP) for sleep. Confirmatory factor analyses …

From Fields To Flu: Mapping H5n1 Zoonotic Risk In California Rice Fields, Mariati Messinger

Walden Dissertations and Doctoral Studies

Highly Pathogenic Avian Influenza (HPAI) H5N1 threatens agriculture, wildlife, and public health in California, where flooded rice fields in the Central Valley provide surrogate wetland habitat for migratory waterfowl and may create ecological interfaces for viral spillover into poultry systems. This quantitative ecological study examined whether county-level rice acreage, Lesser Snow Goose activity, and their interaction were associated with poultry HPAI H5N1 outbreak incidence during complete winter seasons available for analysis. Guided by One Health and disease ecology frameworks, secondary data from USDA, eBird, PRISM, and public surveillance sources were analyzed for 36 county-winter observations using negative binomial regression, logistic …

Marketing Strategies To Enhance Awareness And Attract International Patients In The Medical Tourism Industry Of Trinidad And Tobago, Natasha Rachel Rochford-Chance

Walden Dissertations and Doctoral Studies

Disseminating inadequate service information can limit a business's market appeal and hinder its growth. Business leaders must include comprehensive service information in their marketing strategies, as inadequate service information can make a business seem unappealing to potential clients, undermine competitive position, reduce market share, and diminish profitability. The purpose of this qualitative pragmatic inquiry was to explore the marketing strategies used by medical tourism business leaders in Trinidad and Tobago to attract international patients and increase profitability. The participants were eight medical tourism business leaders with experience in implementing marketing strategies. McCarthy's marketing mix theory of product, price, place, and …

Staff Education To Improve Nurse Competency In Phq-9 And Gad-7 Screening Using A Standardized Behavioral Assessment In An Outpatient Mental Health Setting, Ernest Ogbeide

Walden Dissertations and Doctoral Studies

Evidence-based practice was the basis for this quality improvement project, which involved developing and implementing a staff education program to enhance nurses' competency in administering, scoring, and interpreting behavioral health screening tools (PHQ-9 and GAD-7) for outpatient mental health services. Variability in competency amongst clinical staff to use these standardized screening tools for evaluating anxiety and depression was identified as a problem, as there was no structured, evidence-based education and competency validation process for clinical staff to use, which has the potential to decrease early identification of anxiety and depression among patients and impact clinical assessment and decision-making. The practice …

Imposter Syndrome And Self Determination In Clinical Social Work Supervision, Alexis Tarr

Walden Dissertations and Doctoral Studies

This doctoral project is focused on the social work practice problem of limited understanding of how social workers experience clinical supervision in the context of imposter syndrome. Imposter syndrome can affect confidence, decision making, and overall wellbeing, making it an important issue in clinical social work practice. The purpose of this study was to explore how social workers describe and make meaning of their supervision experiences involving feelings of imposter syndrome. Guiding practice-focused research questions were used to examine how social workers experienced clinical supervision and described autonomy, competence, and relatedness. This study was informed by the self-determination theory, which …

Southeastern United States Community College Instructors’ Perceptions In Implementing Universal Design For Learning, Marshalle Lockhart

Walden Dissertations and Doctoral Studies

The problem that was addressed through this study is that community college instructors struggle to implement universal design for learning (UDL) in Southeastern districts in the United States. Grounded in UDL, which was developed by the Center for Applied Technology, the purpose of this qualitative study was to explore community college instructors’ perceptions on the challenges they face when implementing UDL in their classroom. For this basic qualitative study, semistructured interviews were conducted with eight community college instructors. Using deductive coding, the data were analyzed using a thematic approach with five themes emerging: (a) UDL improves access but does not …

Investigating Tumor-Stromal Interactions That Drive Breast Cancer Angiogenesis And Metastasis, Alessandra Dimauro

Arts & Sciences Graduate Student Theses and Dissertations

Metastatic breast cancer remains one of the most difficult cancers to treat, with a five-year survival rate that drops from 99% for localized disease to just 33% once distant metastases are present. This disparity reflects a fundamental gap in our understanding of how breast tumors spread and highlights the urgent need to improve our understanding of breast cancer metastasis to aid in development of novel therapeutics. Emerging evidence establishes that metastasis requires interactions between tumor cells and non-tumor stromal cells within the tumor microenvironment. The first aim of this dissertation investigates the role of Discoidin Domain Receptor 2 (DDR2), a …

Effects Of O-Glcnacylation And Phosphorylation On Tau Aggregation By Cd And Tem, Andrew Whyte Jr.

Electronic Theses and Dissertations

Alzheimer’s disease (AD) is characterized by the accumulation of extracellular amyloid-β (Aβ) plaques and intracellular neurofibrillary tangles composed of aggregated tau protein. Among the numerous post-translational modifications that regulate tau function, phosphorylation and O-GlcNAcylation have emerged as key modulators of tau aggregation and pathology. While phosphorylation is generally associated with tau misfolding and fibril formation, O-GlcNAcylation has been proposed to exert protective effects through its interplay with phosphorylation. However, the site-specific structural consequences of these modifications remain incompletely understood.

The objective of this work was to develop synthetic tools for the site-specific incorporation of O-GlcNAc and phosphate …