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Articles 7741 - 7770 of 2265357
Full-Text Articles in Entire DC Network
Rethinking Nuclear Liability In The Age Of Small Modular Reactors, Isabella Klesmith
Rethinking Nuclear Liability In The Age Of Small Modular Reactors, Isabella Klesmith
NULR Online
No abstract provided.
Dynlp: Parallel Dynamic Batch Update For Label Propagation In Graph-Based Semi-Supervised Learning, S. M. Shovan, Arindam Khanda, S. M. Ferdous, Sajal K. Das, Mahantesh Halappanavar
Dynlp: Parallel Dynamic Batch Update For Label Propagation In Graph-Based Semi-Supervised Learning, S. M. Shovan, Arindam Khanda, S. M. Ferdous, Sajal K. Das, Mahantesh Halappanavar
Computer Science Faculty Research & Creative Works
Semi-supervised learning aims to infer class labels using only a small fraction of labeled data. In graph-based semi-supervised learning, this is typically achieved through label propagation to predict labels of unlabeled nodes. However, in real-world applications, new data often arrives in batches, and stale data often becomes irrelevant. Each time a new batch appears, reapplying the traditional label propagation algorithm to recompute all labels is redundant, computationally intensive, and inefficient. To address the absence of an efficient label propagation update method, we propose DynLP, a novel GPU-centric Dynamic Batched Parallel Label Propagation algorithm that performs only the necessary updates, propagating …
Enhancing Construction Simulation Optimization Performance Through Variance Reduction Techniques, Mohammed Mawlana, Amin Hammad
Enhancing Construction Simulation Optimization Performance Through Variance Reduction Techniques, Mohammed Mawlana, Amin Hammad
College of Architecture and the Built Environment Faculty Papers
Simulation optimization has been used to analyze construction operations and support planning decisions under uncertainty. It enables the identification of effective planning strategies throughout a project’s lifecycle. However, the use of stochastic simulation to evaluate alternative strategies results in higher computational demands and the generation of inferior solutions within the resulting optimal solutions. This study examines the feasibility of overcoming these issues by implementing variance reduction techniques into a discrete-event simulation optimization framework. Three variance reduction techniques are evaluated in a case study: Common Random Numbers, Antithetic Variates, and a combined application of both. While these techniques are well established …
Developmental Stability Of Task-Rest Neural Efficiency In Youth Using A Threat And Cognitive Control Task, Parmis Khosravi, Julia O. Linke, Anjali D. Poe, Chase Antonacci, Reut Naim, Elise M. Cardinale, Katharina Kircanski, Anderson M. Winkler, Nathan A. Fox, Daniel Samuel Pine, Simona P. Haller
Developmental Stability Of Task-Rest Neural Efficiency In Youth Using A Threat And Cognitive Control Task, Parmis Khosravi, Julia O. Linke, Anjali D. Poe, Chase Antonacci, Reut Naim, Elise M. Cardinale, Katharina Kircanski, Anderson M. Winkler, Nathan A. Fox, Daniel Samuel Pine, Simona P. Haller
School of Medicine Publications
Behaviors arise from coordinated neural activity across diverse spatial and temporal scales. Prior work has linked better task performance and cognitive functioning to patterns of global network connectivity requiring minimal reconfiguration when switching between task demands. This metric indexing similarity in functional connectivity across task and rest has been termed “neural efficiency.” Here we assess stability of neural efficiency over approximately 3 years in adolescence, specificity across two task-rest combinations and associations with anxiety. At approximately age 16 and/or 19, 95 participants completed a resting state scan alongside a cognitive control and/or threat task. Neural efficiency was quantified as partial …
Role Of Guidelines, Legislation, Litigation And Mechanisms For Sudep Communication In The Uk And In The Usa: A State-Of-The-Art Review, Rohit Shankar
Role Of Guidelines, Legislation, Litigation And Mechanisms For Sudep Communication In The Uk And In The Usa: A State-Of-The-Art Review, Rohit Shankar
Peninsula Medical School
IntroductionSudden unexpected death in epilepsy (SUDEP) remains a leading cause of premature mortality in people with epilepsy despite decades of research and guideline development.MethodsThis state-of-the-art narrative review synthesises multidisciplinary evidence from clinical guidelines, epidemiology, legal frameworks, policy initiatives, and advocacy sources in the United Kingdom (UK) and United States of America (USA). The review is structured to examine current practice (“where are we now”), evolution of influencing mechanisms (“how did we get here”), and future directions for improving SUDEP prevention (“where should we go next”).ResultsWhere are we now SUDEP risk communication remains inconsistent despite clear guideline recommendations. Implementation is hindered …
3d Semi-Analytical Thermo-Elasto-Plastic Model For Additive Manufacturing, Tao Liu, Ming C. Leu, Edward C. Kinzel, Chinedum Okwudire
3d Semi-Analytical Thermo-Elasto-Plastic Model For Additive Manufacturing, Tao Liu, Ming C. Leu, Edward C. Kinzel, Chinedum Okwudire
Mechanical and Aerospace Engineering Faculty Research & Creative Works
In additive manufacturing (AM), stress field drives distortion and warping and promotes delamination and cracking. Fast, accurate stress prediction is therefore essential for AM process planning and control, including real-time adaptive control, AM digital twins, data-driven and physics-driven workflows. However, spot-wise thermo-elasto-plastic finite element method (FEM) are often too slow for design iteration or real time use. Existing semi-analytical thermo-elasto-plastic approaches achieve high speed but are largely limited to 2D. In this paper, a full 3D semi-analytical thermo-elasto-plastic model for AM is built. The method uses a spot-wise analytical thermal field as the load and computes displacements and stresses via …
Purification And Concentration Of Model Viruses Using Single-Pass Tangential Flow Filtration, Luis Alberto Mejía-Manzano, Lynn M. Manchester, Grace Wallis, Kan Wang, Bruce Lee, Michael Betenbaugh, Caryn Heldt
Purification And Concentration Of Model Viruses Using Single-Pass Tangential Flow Filtration, Luis Alberto Mejía-Manzano, Lynn M. Manchester, Grace Wallis, Kan Wang, Bruce Lee, Michael Betenbaugh, Caryn Heldt
Michigan Tech Publications
The vaccine and viral vector industry is growing at an accelerated rate. To improve harvest and purification processes, the development of continuous membrane-based operations, such as normal flow filtration (NFF) and single pass tangential flow filtration (SPTFF) for concentration were explored. This work was conducted using two model viruses, non-enveloped porcine parvovirus (PPV) and enveloped Suid herpesvirus (SuHV). The viruses are in the same family as the gene therapy vectors adeno associated virus and herpes simplex virus, respectively. SPTFF design started with batch TFF for membrane selection. Hollow fiber membranes with a 100 and 300 kDa molecular weight cut off …
A Dual-Crosslinked Metallo-Elastomer Platform For Architecture-Directed Vascular Remodeling, Narangerel Gantumur, Shuhao Jiao, Xiaochu Ding, Simon Van Herck, Isabella Frangiosa, Emily Kopchick, Caitlin Maureen Purdy, Ty Walker, Aarati Kharal, Ying Grace Chen
A Dual-Crosslinked Metallo-Elastomer Platform For Architecture-Directed Vascular Remodeling, Narangerel Gantumur, Shuhao Jiao, Xiaochu Ding, Simon Van Herck, Isabella Frangiosa, Emily Kopchick, Caitlin Maureen Purdy, Ty Walker, Aarati Kharal, Ying Grace Chen
Michigan Tech Publications
The engineering of durable small-diameter vascular grafts remains constrained by the challenge of simultaneously achieving mechanical robustness, controlled degradation, and instructive scaffold architecture. Here, we report a programmable dual-crosslinked metallo-elastomer platform, poly(1,3-propylene itaconate-co-2,2′-bipyridine-5,5′-dicarboxylate-co-succinate-co-sebacate) (M-PBIS), that integrates dynamic metal–ligand coordination with covalent crosslinking to enable orthogonal control over network mechanics, time-dependent viscoelastic behavior, and processability. PBIS polymers were synthesized by modular step-growth polyesterification, allowing independent tuning of backbone composition, bipyridine ligand density for metal coordination, and alkene (C = C) content for covalent crosslinking. This multidimensional design space allowed systematic tuning of tensile elastic modulus (0.06–3.2 MPa), extensibility (53%–491%), toughness (66–1339 …
Community Ai Resilience: A Five-Pillar Framework For Preparing Communities For An Ai-Transformed World, Robin D. Anderson, Nicholas A. Curtis
Community Ai Resilience: A Five-Pillar Framework For Preparing Communities For An Ai-Transformed World, Robin D. Anderson, Nicholas A. Curtis
Faculty Scholarship
Current artificial intelligence readiness strategies focus almost exclusively on two priorities: expanding access to AI tools and developing a technical workforce. While necessary, these efforts are insufficient. AI seems likely to transform how people work and, with that, to reshape how individuals derive meaning, how families function, and how communities organize. This paper presents the Community AI Resilience Framework, a five-pillar model addressing the human systems dimensions of AI transformation: (1) Economic Resilience and Regulatory Adaptation; (2) Social Cohesion and Belonging Infrastructure; (3) Psychological Resilience and Identity Reconstruction; (4) Civic and Educational Renewal; and (5) Ecological and Leisure Commons Management. …
The Double Attraction Paradox, Rem Jaen D. Krafft
The Double Attraction Paradox, Rem Jaen D. Krafft
Publications and Research
The Double Attraction Paradox is a podcast series that teaches adolescents how to navigate attraction through body language, limerence, and mirroring while understanding the psychology behind emotional connection. It is a manuscript that combines personal experience, observations, and research, inspired by Rem Jaen D. Krafft's high school crush. Not only does it provide a guide for teenagers and young adults, but it also encourages readers to better understand attraction, communication, and emotional development. The final chapter examines how peer pressure, traditional high school cliques, fear of rejection, and fear of intimacy may influence societal norms, emotional contagion, and relationship formation …
Recent Advancements In The Characterization Of Archaeological Wood, Amir Ghavidel, Reza Hosseinpourpia, Jianhui Zhou
Recent Advancements In The Characterization Of Archaeological Wood, Amir Ghavidel, Reza Hosseinpourpia, Jianhui Zhou
Michigan Tech Publications
Archeological wood is a vital organic archive, yet its degraded state challenges traditional methods for species identification, provenance resolution, and decay assessment. This review synthesizes state-of-the-art advances—integrating artificial intelligence, isotopic systems, and molecular biology—and proposes a four-tier hierarchical diagnostic framework that moves the field from qualitative description to quantitative, high-resolution analysis. Landmark case studies demonstrate how multi-scalar data fusion provides mechanistic understanding of structural decay inaccessible through conventional approaches.
The Business Next Door: How The Essenburgs Became The Chick-Fil-A Of The Car Wash Industry, Steve Vanderveen
The Business Next Door: How The Essenburgs Became The Chick-Fil-A Of The Car Wash Industry, Steve Vanderveen
University Faculty Publications and Creative Works
It is difficult to imagine a more entrepreneurial family than the Essenburgs.
Synergistic Effects Of Arbuscular Mycorrhizal Fungi And Foliar Nitrogen–Phosphorus Application On Maize Productivity Under Irrigated And Rainfed Conditions, Mst. Lailatul Ferdows, Saima Biswas, Mizanur Rahman, F. M.Jamil Uddin, Md. Nayan, Aporna Tabassum Api, Mohaiminul Islam, Nadia Islam, Swapan Kumar Paul, Md. Harun Rashid
Synergistic Effects Of Arbuscular Mycorrhizal Fungi And Foliar Nitrogen–Phosphorus Application On Maize Productivity Under Irrigated And Rainfed Conditions, Mst. Lailatul Ferdows, Saima Biswas, Mizanur Rahman, F. M.Jamil Uddin, Md. Nayan, Aporna Tabassum Api, Mohaiminul Islam, Nadia Islam, Swapan Kumar Paul, Md. Harun Rashid
School of Earth, Environmental, & Marine Sciences Faculty Publications
A field experiment was conducted at the Agronomy Field Laboratory of Bangladesh Agricultural University to evaluate the effects of arbuscular mycorrhizal fungi (AMF) inoculation and foliar supplementation of nitrogen (N) and phosphorus (P) on the performance of maize (Zea mays L.) under irrigated and rainfed conditions. The experiment followed a randomised complete block design with two levels of AMF (inoculated and non-inoculated) and four foliar treatments (no N and P, N only, P only, and combined N + P). The recommended dose of fertiliser (RDF) was applied as a soil application to all treatments. AMF inoculation significantly increased grain yield …
High-Order Brain Interactions During Ketamine-Induced State Changes: A Functional Marker Of Response In Late-Life Treatment-Resistant Depression?, Krisha Shah, Rubén Herzog, Alan C Swann, Brittany O'Brien, Rahul Balakrishnan, Sanjay J Mathew, Nicholas Murphy
High-Order Brain Interactions During Ketamine-Induced State Changes: A Functional Marker Of Response In Late-Life Treatment-Resistant Depression?, Krisha Shah, Rubén Herzog, Alan C Swann, Brittany O'Brien, Rahul Balakrishnan, Sanjay J Mathew, Nicholas Murphy
Faculty, Staff and Students Publications
Ketamine is a fast-acting intervention for treatment-resistant depression (TRD), yet only a subset of patients show robust clinical response, and the underlying neural mechanisms remain unclear. High-order interactions (HOI) derived from multivariate information theory provide a framework for examining nonlinear dependencies among brain regions beyond pairwise connectivity. One such metric, the O-information, captures the balance between synergistic and redundant interactions across three or more variables. In this secondary analysis of a randomized, double-blind, midazolam-controlled trial (NCT02556606), we examined EEG-derived HOI in 30 late-life veterans with TRD following a single 40-minute intravenous infusion of ketamine (0.1, 0.25, 0.5 mg/kg; n = …
International Fantasy Literature Conference Headed To Weatherford - Weatherford Daily News, Phillip Fitzsimmons, David Topolewski, Liliana Walker
International Fantasy Literature Conference Headed To Weatherford - Weatherford Daily News, Phillip Fitzsimmons, David Topolewski, Liliana Walker
Faculty Articles & Research
This article was written by David Topolewski of Weatherford Daily News about the upcoming conference, MythCon 54, that is coming to Weatherford on July 24 - 27. Pictured is SWOSU Archivist Phillip Fitzsimmons discussing the conference with WDN Staff Writer Liliana Walker.
The Coupled Hydrology–Human Activity Information (Chhai) Dataset: A Global Benchmark Dataset For Model Comparison And Evaluation, Azara Boschee, Aneseh Alborzi, Augustina Clara Alexander, Berit Arheimer, Salsebil Bel Hadj Ali, Günter Blöschl, Andrea Castelletti, Xi Chen, Aniya Dogra, Erhu Du, Jesse Duku, Aldo Fiori, Margaret Garcia, Salvatore Grimaldi, Naota Hanasaki, Yeonjoo Kim, Heidi Kreibich, Chenyuan Li, Ali Mehran, For Full Author List, See Comments Below
The Coupled Hydrology–Human Activity Information (Chhai) Dataset: A Global Benchmark Dataset For Model Comparison And Evaluation, Azara Boschee, Aneseh Alborzi, Augustina Clara Alexander, Berit Arheimer, Salsebil Bel Hadj Ali, Günter Blöschl, Andrea Castelletti, Xi Chen, Aniya Dogra, Erhu Du, Jesse Duku, Aldo Fiori, Margaret Garcia, Salvatore Grimaldi, Naota Hanasaki, Yeonjoo Kim, Heidi Kreibich, Chenyuan Li, Ali Mehran, For Full Author List, See Comments Below
Faculty Research, Scholarly, and Creative Activity
To enhance hydrologic modeling, the hydrology community has developed benchmark datasets (e.g. Model Parameter Estimation Experiment, MOPEX), providing standardized data for model evaluation and parameter estimation. However, these datasets primarily focus on modeling natural hydrologic processes, leaving a critical gap in understanding the role of human influences. Here, we introduce the Coupled Hydrology-Human Activity Information (CHHAI) dataset, a benchmark dataset that integrates coupled human–water data from regions across all continents, excluding Antarctica. CHHAI incorporates data from 25 regions that cover various human impacts such as reservoir management, flood protection, river management policies, land use changes, and water use. Each basin …
Perez V. Meisner
All Decisions
In this HP proceeding, a default order and money judgment had been entered against Respondent-owners before they appeared by counsel. The court vacated the default judgment, finding Respondent-owners presented a reasonable excuse for their non-appearance and a meritorious defense. The court reaffirmed the April 2025 order to correct and allowed Respondent-owners to file a late answer.
Reducing Communicable-Disease Risk After Earthquakes: Vaccination And Prevention Lessons For Venezuela's Doublet, Alfonso J Rodriguez-Morales, Ivan Arturo Rodríguez-Sabogal, Adriana Sucari, Wendy Moncada, Lili Vanessa Hernández-Serrano, Florencia Escarrá, Pasesa Pascuala Quispe-Torrez, Francisco Javier Membrillo, Tomás Orduna, Susana Lloveras, Tânia S S Chaves, Miguel M Cabada, Cecilia Perret, René Echavarría, Ana F Ribeiro, Melinda Tanabe, Fernando Bazzino, Maximiliano Ramirez, Baruch Diaz, Karen Mirna Loro Morejón, Karen Daly, Reinaldo Rosas, Maria Belen Lopez, Cristina Miranda, Marisa Liliana Fernandez, Yasemin Özsürekçi, Wasin Matsee, Yenddy Carrero, Cristian Biscayart, Sergio Cimerman, Maria L Avila-Aguero, Roberto Debbag, Jose Brea, Alejandro Risquez, Jaime David Acosta-España, Rolando Ulloa-Gutierrez, Carlos Espinal, Carlos N Torres-Martinez, Marta González-Sanz, Aula Abbara, Jill Weatherhead, Bernal Cordero, Virgilio Lezcano, Amanda Guerrero, Herberth Maldonado, Luis Cuellar, Ines Ceron, Yori Roque, Melisa Florentin, Rosa Infante, Ana Carvajal, Lily M Soto-Ávila, Marbelys Hernández, Hector Villaroel, Gianmary Miozzi, Rafael Navas, Moraima Hernández, Carlos Pérez-Vega, Manuela Mérida, David A Forero-Peña, Juan-Carlos Navarro, Claudia Beltrán-Arroyave, Mario Masana
Reducing Communicable-Disease Risk After Earthquakes: Vaccination And Prevention Lessons For Venezuela's Doublet, Alfonso J Rodriguez-Morales, Ivan Arturo Rodríguez-Sabogal, Adriana Sucari, Wendy Moncada, Lili Vanessa Hernández-Serrano, Florencia Escarrá, Pasesa Pascuala Quispe-Torrez, Francisco Javier Membrillo, Tomás Orduna, Susana Lloveras, Tânia S S Chaves, Miguel M Cabada, Cecilia Perret, René Echavarría, Ana F Ribeiro, Melinda Tanabe, Fernando Bazzino, Maximiliano Ramirez, Baruch Diaz, Karen Mirna Loro Morejón, Karen Daly, Reinaldo Rosas, Maria Belen Lopez, Cristina Miranda, Marisa Liliana Fernandez, Yasemin Özsürekçi, Wasin Matsee, Yenddy Carrero, Cristian Biscayart, Sergio Cimerman, Maria L Avila-Aguero, Roberto Debbag, Jose Brea, Alejandro Risquez, Jaime David Acosta-España, Rolando Ulloa-Gutierrez, Carlos Espinal, Carlos N Torres-Martinez, Marta González-Sanz, Aula Abbara, Jill Weatherhead, Bernal Cordero, Virgilio Lezcano, Amanda Guerrero, Herberth Maldonado, Luis Cuellar, Ines Ceron, Yori Roque, Melisa Florentin, Rosa Infante, Ana Carvajal, Lily M Soto-Ávila, Marbelys Hernández, Hector Villaroel, Gianmary Miozzi, Rafael Navas, Moraima Hernández, Carlos Pérez-Vega, Manuela Mérida, David A Forero-Peña, Juan-Carlos Navarro, Claudia Beltrán-Arroyave, Mario Masana
Faculty, Staff and Students Publications
No abstract provided.
Beyond Step Counts: Dual Perspectives On Designing Interactive Technologies To Support Outdoor Movement In Older Adults, Fatima Badmos, Emma Murphy, Peterson Jean, Damon Berry
Beyond Step Counts: Dual Perspectives On Designing Interactive Technologies To Support Outdoor Movement In Older Adults, Fatima Badmos, Emma Murphy, Peterson Jean, Damon Berry
Research Outputs: 2025-Present
Outdoor movement supports older adults' health and wellbeing, yet participation is constrained by environmental, physical, and social barriers. Existing technologies often prioritise clinical risk management and quantified functional metrics, and rarely integrate older adults' lived experience alongside physical activity experts' perspectives in early design. We conducted four focus group workshops with 24 urban dwelling older adults (63 to 91 years) and semi structured online interviews with 11 physical activity experts. Data were analysed using thematic analysis and grounded theory coding, then triangulated to identify convergent themes, divergent perspectives, and complementary views. Key tensions concerned risk management versus independence, clinical benchmarks …
Research Competence, Technology Skills As Correlates For Job Satisfaction Among Librarians In Universities In Delta State, Oghuvbu Blessing
Research Competence, Technology Skills As Correlates For Job Satisfaction Among Librarians In Universities In Delta State, Oghuvbu Blessing
Library Philosophy and Practice (e-journal)
Librarians perform academic and professional functions in universities, which require them to have job satisfaction for effective job performance. This study worked at the intersection of research competencies, technological skills and job satisfaction among librarians in universities in Delta State, Nigeria. The population of the study was the entire 81 librarians in universities in the state. A total population sampling was adopted. Data collected using a structured questionnaire was analysed using mean and standard deviation. The study found a high level of research competence, technology skills, and job satisfaction among the librarians in the universities. Conclusion the study found that …
Advancing Bioinformatics With Language Models: Components, Applications, And Perspectives, Jiajia Liu, Mengyuan Yang, Yankai Yu, Haixia Xu, Tiangang Wang, Kang Li, Xiaobo Zhou
Advancing Bioinformatics With Language Models: Components, Applications, And Perspectives, Jiajia Liu, Mengyuan Yang, Yankai Yu, Haixia Xu, Tiangang Wang, Kang Li, Xiaobo Zhou
Faculty, Staff and Student Publications
Large language models (LLMs) are deep learning-based artificial intelligence models that have achieved remarkable success in natural language processing. Typically composed of neural networks with billions of parameters, they are trained on massive unlabeled datasets using self-supervised or semi-supervised learning. Beyond language, LLMs hold immense potential for addressing complex bioinformatics challenges. This review provides a comprehensive overview of transformer-based model applications in genomics, transcriptomics, proteomics, drug discovery, and single-cell analysis. We discuss critical components, including tokenization strategies for diverse biological data, transformer architectures, attention mechanisms, and pretraining approaches. We also survey currently available foundation models and their downstream applications across …
Ai-Resistant And Ai-Resilient Assessment In Higher Education: A Systematic Review Of Validity-Grounded Strategies, Institutional Frameworks, And Equity Implications, Asrat Genet Amnie
Ai-Resistant And Ai-Resilient Assessment In Higher Education: A Systematic Review Of Validity-Grounded Strategies, Institutional Frameworks, And Equity Implications, Asrat Genet Amnie
Publications and Research
The emergence of large language models has precipitated a fun damental disruption to higher education assessment. Conventional instruments are susceptible to AI-assisted completion, threatening construct validity across disciplines and institutional contexts. When submitted work reflects AI capability rather than student competency, the inferential chain from performance to qualifica tion is invalidated – a problem of design rather than detection. This systematic review makes two contributions. First, it theorises and grounds the distinction between AI-resistant assessment, which seeks to prevent or impede AI access through containment, and AI-resilient assessment, which assesses genuine human cogni tive performance of intrinsic educational value regardless …
Efficient Dynamic Mechanism Design Without A Common Prior, Dirk Bergemann, Marek Bojko
Efficient Dynamic Mechanism Design Without A Common Prior, Dirk Bergemann, Marek Bojko
Cowles Foundation Discussion Papers
We study efficient dynamic mechanism design with independent private values when agents do not share a common prior over the stochastic environment. Each agent privately observes the stochastic kernel governing the evolution of her own type and may hold arbitrary beliefs about the kernels of others. We extend the agents’ type space to include the kernel itself and show that the dynamic team mechanism of Athey and Segal (2013) and the dynamic pivot mechanism of Bergemann and Välimäki (2010) implement the socially efficient allocation in periodic ex-post equilibrium. We further show that kernels can be elicited only once, at the …
Clinical Outcomes After Ulnar Collateral Ligament Reconstruction With Palmaris Longus Versus Gracilis Autograft In Baseball Players: A Cohort Analysis, Michael C. Ciccotti, Brooks Martino, Frank Cautela, Nathaniel Tchangou, Daniel Kwak, Eric Didomenico, Harrison S. Fellheimer, Christopher C. Dodson, Steven B. Cohen, Michael G. Ciccotti
Clinical Outcomes After Ulnar Collateral Ligament Reconstruction With Palmaris Longus Versus Gracilis Autograft In Baseball Players: A Cohort Analysis, Michael C. Ciccotti, Brooks Martino, Frank Cautela, Nathaniel Tchangou, Daniel Kwak, Eric Didomenico, Harrison S. Fellheimer, Christopher C. Dodson, Steven B. Cohen, Michael G. Ciccotti
Rothman Institute Papers
BACKGROUND: Ulnar collateral ligament (UCL) reconstruction (UCLR) is a common procedure for overhead athletes, particularly baseball players sustaining partial or full UCL tears. Palmaris longus (PL) and gracilis (GR) autografts are the most frequently used graft sources, yet limited data compare clinical outcomes in baseball athletes.
PURPOSE: To compare patient-reported outcomes after UCLR with PL versus GR autografts in baseball players.
STUDY DESIGN: Cohort study; Level of evidence, 3.
METHODS: Patients who underwent isolated UCLR with either PL or GR autograft and a minimum of 2 years of follow-up were identified. All reconstructions were performed using the Modified Jobe or …
Aberrant Ciliogenesis Induced By Enhanced Bmp Signaling Causes Heterotopic Ossification, Hiroyuki Yamaguchi, Jianbo Wang, Fangfang Yan, Jiarui Bi, Radbod Darabi, William R. Lagor, Zhongming Zhao, Aris N. Economides, Yuji Mishina, Yoshihiro Komatsu
Aberrant Ciliogenesis Induced By Enhanced Bmp Signaling Causes Heterotopic Ossification, Hiroyuki Yamaguchi, Jianbo Wang, Fangfang Yan, Jiarui Bi, Radbod Darabi, William R. Lagor, Zhongming Zhao, Aris N. Economides, Yuji Mishina, Yoshihiro Komatsu
Faculty, Staff and Student Publications
Bone morphogenetic protein (BMP) signaling is a principal driver of heterotopic ossification (HO), yet how aberrant BMP activity structurally reprograms cellular signaling machinery to develop HO remains unclear. Here, we identify BMP signaling as a direct upstream regulator of ciliogenesis that coordinates a multi-stage, pro-osteochondrogenic signaling relay during HO. Using a conditional gain-of-function BMP mouse model (Acvr1Q207D/+), we demonstrate that enhanced BMP signaling promotes primary cilium biogenesis and axonemal elongation through canonical Smad1/5/9-dependent transcriptional activation of intraflagellar transport (IFT) Ift20, a core component of the IFT machinery. Rather than operating via a singular downstream cascade, these elongated …
Tranexamic Acid In High-Risk Shoulder Arthroplasty Patients: Safety Across Thromboembolic, Cardiac, Renal, And Neurologic Risk Profiles, Tarishi Parmar, Akin Adio, Asim Handy, Mohammad Daher, Alec Kellish, Adam Khan, Joseph A. Abboud
Tranexamic Acid In High-Risk Shoulder Arthroplasty Patients: Safety Across Thromboembolic, Cardiac, Renal, And Neurologic Risk Profiles, Tarishi Parmar, Akin Adio, Asim Handy, Mohammad Daher, Alec Kellish, Adam Khan, Joseph A. Abboud
Rothman Institute Papers
INTRODUCTION: Tranexamic acid (TXA) effectively reduces blood loss and transfusion requirements in shoulder arthroplasty. However, concerns regarding thromboembolic, neurologic, cardiac, and renal complications have limited its use in medically high-risk patients. This study evaluated temporal trends and the safety of TXA in high-risk patients undergoing total shoulder arthroplasty (TSA).
METHODS: A retrospective cohort study was conducted using TriNetX, identifying patients who underwent shoulder arthroplasty (2012-2025). Patients were stratified by preexisting high-risk conditions, including prior thromboembolism, renal failure, atrial fibrillation, seizure disorders, and visual disturbances. Within each subgroup, patients receiving TXA were propensity score-matched to those who did not. Perioperative TXA …
Energy Efficiency Limits And Future Electricity Demand Of Computing Devices, Ricardo Pinto, Tiago Domingos, Paul E. Brockway, Matthew Kuperus Heun, Tânia Sousa
Energy Efficiency Limits And Future Electricity Demand Of Computing Devices, Ricardo Pinto, Tiago Domingos, Paul E. Brockway, Matthew Kuperus Heun, Tânia Sousa
University Faculty Publications and Creative Works
- ICT (information and communication technologies) represented 4% of the world electricity consumption in 2020;
- Computing devices represented 2% of the world electricity consumption in 2020;
- In recent scenarios datacentre electricity demand reaches 3% of world electricity in 2030, and more than 4% in 2035
Understanding The Role Of Entropy In Designing High-Performance Thermoelectrics, Subrata Ghosh, Soongyu Kwon, Wenjie Li, Dipika Mandal, Amin Nozariasbmarz, Marcia Ahn, Sumanta K. Karan, Allison M. Beese, Yi Xia, Shashank Priya, Bed Poudel
Understanding The Role Of Entropy In Designing High-Performance Thermoelectrics, Subrata Ghosh, Soongyu Kwon, Wenjie Li, Dipika Mandal, Amin Nozariasbmarz, Marcia Ahn, Sumanta K. Karan, Allison M. Beese, Yi Xia, Shashank Priya, Bed Poudel
Mechanical and Materials Engineering Faculty Publications and Presentations
The design of high-entropy alloys is effective in lowering thermal conductivity but often reduces carrier mobility, thereby limiting electrical transport properties. Understanding the relationship among configurational entropy, thermal conductivity, and carrier mobility in high-entropy alloys is critical for enhancing thermoelectric performance. We demonstrate that a systematic and substantial increase in configurational entropy in half-Heusler alloys leads to an asymptotic reduction of lattice thermal conductivity. The reduced phonon group velocity and enhanced phonon scattering induced by atomic-scale chemical disorder result in a low lattice thermal conductivity of 2 watts per meter per kelvin at room temperature, with an achievable minimum of …
Climate-Responsive Design For Sustainable Construction: Passive Strategies In Domestic Architecture Supporting Sustainability, Nahed Chakouf
Climate-Responsive Design For Sustainable Construction: Passive Strategies In Domestic Architecture Supporting Sustainability, Nahed Chakouf
All Works
This study explores climate-responsive design in domestic architecture, focusing on the application and effectiveness of passive strategies across various climatic regions, including the UK, hot-arid, tropical, and cold climates. A qualitative comparative case study method was used to explore different passive design strategies, integration of sustainability, procurement, the coordination of stakeholders, and compliance with regulations in residential architectural projects under varying climate conditions. Drawing from a combination of historical case studies and original architectural projects, the research evaluates how spatial configuration, material selection, solar orientation, shading, ventilation, and insulation are optimized to achieve thermal comfort and energy efficiency. In temperate …
Childhood Development Podcast Assignment, Masha Komolova
Childhood Development Podcast Assignment, Masha Komolova
Open Educational Resources
The assignment asks students to analyze how a particular aspect of their childhood has shaped them into a person they are today. Students will use literature review, interview with a caregiver, and their own reflection to analyze their childhood development and its effects on them. The assignment will be in the form of a podcast.