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Articles 5251 - 5280 of 2259251
Full-Text Articles in Entire DC Network
Connected, Confident, And Cautious: Gen Z’S Emerging Financial Life, Stephen Roll, Jayden Liu, Guangli Zhang
Connected, Confident, And Cautious: Gen Z’S Emerging Financial Life, Stephen Roll, Jayden Liu, Guangli Zhang
Center for Social Development Research
The economic uncertainty Gen Z is facing as they enter adulthood is in some ways familiar and in some ways unprecedented. Like millennials, who came of age during the Great Recession, today’s young adults have experienced a major economic disruption early in their financial lives. The COVID-19 pandemic, followed by inflation, interest rate volatility, and affordability pressures, has shaped the conditions under which Gen Z is beginning to earn, save, borrow, and invest. Yet, Gen Z is entering adulthood in a financial environment that looks very different from the one earlier generations encountered. This brief draws on three complementary datasets …
Comparison Of Healthcare Utilization Among Patients With Down Syndrome In Specialty Care Vs Non-Specialty Care, Akaninyene Noah, Hannah Tavalire, Veronica Fitzpatrick, Hannah Graham, Shelly Verma, Laura Krohn, Daniel Vockeroth, Brian Chicoine
Comparison Of Healthcare Utilization Among Patients With Down Syndrome In Specialty Care Vs Non-Specialty Care, Akaninyene Noah, Hannah Tavalire, Veronica Fitzpatrick, Hannah Graham, Shelly Verma, Laura Krohn, Daniel Vockeroth, Brian Chicoine
Advocate GME
No abstract provided.
Digital Age: A Collection Inspired By Nostalgia, Memory, And A Late-2000’S Youth, Syd Libby
Digital Age: A Collection Inspired By Nostalgia, Memory, And A Late-2000’S Youth, Syd Libby
Art and Art History Summer Fellows
The cycle of visual culture, objects, and entertainment marketed to children changes rapidly. However, the objects, sounds, music, places and people we attach to as young people tend to hold weight in our lives and shape our understanding of the world. “Digital Age” is a series of paintings, sculptures and fiber works inspired by these feelings of nostalgia for a time that wasn’t really that long ago; around the late 2000’s – early 2010’s. I took this idea of nostalgia and represented it in different forms; both the images of me as a kid, alongside the objects I associate with …
Minerals Rock!: Improving Audience Engagement And Interest In Stem Through Enhancement Of The In-Person And Online Mineral Collection At Ursinus College, Juliette Lyons
Environment and Sustainability Summer Fellows
Museums are a vital source of educational resources for the general public. They provide information on a variety of topics and disciplines and encourage visitors to be excited about and engaged in learning something new. As we work to comprehend key topics such as climate change, it is especially important for the broader public to better understand science, including geology. While the geological collection at Ursinus, Pieces of Earth’s History, is not in a museum, implementing methods that museums use can improve the reception of the collection. Through the application of research gathered through articles, journals, books, and talking with …
Simbinder-If: Structure-Aware Antibody Affinity Optimization Via Efficient Preference Learning, Xinyan Zhao, Yi-Ching Tang, Rivaaj Monsia, Victor J Cantu, Ashwin Kumar Ramesh, Siyu Yang, Xiaozhong Liu, Zhiqiang An, Xiaoqian Jiang, Yejin Kim
Simbinder-If: Structure-Aware Antibody Affinity Optimization Via Efficient Preference Learning, Xinyan Zhao, Yi-Ching Tang, Rivaaj Monsia, Victor J Cantu, Ashwin Kumar Ramesh, Siyu Yang, Xiaozhong Liu, Zhiqiang An, Xiaoqian Jiang, Yejin Kim
The Brown Foundation: Institute of Molecular Medicine
Motivation: Antibody therapeutic efficacy depends on high-affinity target engagement, yet laboratory affinity maturation is slow and costly. Most protein language models (PLMs) lack explicit training for high affinity, and current preference optimization methods introduce computational overhead without clear affinity improvements. Therefore, structure-aware and parameter-efficient approaches for antibody affinity optimization are urgently needed.
Results: We propose SimBinder-IF, a structure-aware antibody optimization model trained by freezing the Evolutionary Scale Modeling inverse folding (ESM-IF) structure encoder and fine-tuning only its decoder via Simple Preference Optimization (SimPO) to prefer stronger binders. In generalization tests across seven held-out complexes (93 477 mutants), SimBinder-IF shows a …
Higher Mortality And Distinct Complications After Anterior Cervical Discectomy And Fusion In Dialysis Patients, Despite Improvements Over Prior Decade: A National Inpatient Study, Mitchell K. Ng, Leonidas E. Mastrokostas, Paul G. Mastrokostas, William A. Green, Joshua Mathew, Gregorio Baek, Yasmine Eichbaum, Yulia Lee, Morgan Hitchner, Jonathan Dalton, Adam Fano, Alec Giakas, Rajendra Singh, Brendan Reitman, Afshin E. Razi, Daniel R. Fassett, Alan S. Hilibrand, Alex R. Vaccaro, Christopher K. Kepler, Gregory D. Schroeder, Andrew P. Alvarez
Higher Mortality And Distinct Complications After Anterior Cervical Discectomy And Fusion In Dialysis Patients, Despite Improvements Over Prior Decade: A National Inpatient Study, Mitchell K. Ng, Leonidas E. Mastrokostas, Paul G. Mastrokostas, William A. Green, Joshua Mathew, Gregorio Baek, Yasmine Eichbaum, Yulia Lee, Morgan Hitchner, Jonathan Dalton, Adam Fano, Alec Giakas, Rajendra Singh, Brendan Reitman, Afshin E. Razi, Daniel R. Fassett, Alan S. Hilibrand, Alex R. Vaccaro, Christopher K. Kepler, Gregory D. Schroeder, Andrew P. Alvarez
Rothman Institute Papers
Introduction: Dialysis patients undergoing anterior cervical discectomy and fusion (ACDF) face elevated perioperative risk due to complex comorbidities. This study aimed to (1) identify associations between dialysis status and perioperative complications after ACDF, (2) quantify differences in length of stay (LOS), hospitalization costs, and discharge disposition, and (3) provide a contemporary national benchmark for outcomes in this high-risk population. Materials and Methods: The 2016–2022 National Inpatient Sample was queried for adult elective ACDF cases. Dialysis dependence was identified through International Classification of Diseases-10 codes for end-stage renal disease with hemodialysis or peritoneal dialysis. Demographics, comorbidities, complications, LOS, costs, and discharge …
20260724: Journalism & Media, 1961-1962, College Of Liberal Arts
20260724: Journalism & Media, 1961-1962, College Of Liberal Arts
Guides to University Archives
These items include materials from the department of Journalism at Marshall University from 1961-1962. Items were received in at an earlier date (likely in the 1980s) and include notable materials from events on campus such as the dedication of Prichard Hall, the Men's Physical Education Building, the signing of Marshall University Bill, and a talk that President Stewart Smith gave on Human Rights in the Campus Christian Center.
Jiaherb Inc V. Mtc Industries Inc
The B-Ripped Point-Of-Care Ultrasound Protocol: Faster Diagnostic Reasoning For Undifferentiated Dyspnea In The Ed, Adil Ashraf, Savithri Manu, Johnson Varghese, Aubrie Ford
The B-Ripped Point-Of-Care Ultrasound Protocol: Faster Diagnostic Reasoning For Undifferentiated Dyspnea In The Ed, Adil Ashraf, Savithri Manu, Johnson Varghese, Aubrie Ford
URGENT Matters
No abstract provided.
Leaving Against Medical Advice In The Ed: Understanding A Preventable Threat To Patient Safety, Chhaya Gupta, Shakti Shishodia, Pallavi Sehgal, Deborah Eke
Leaving Against Medical Advice In The Ed: Understanding A Preventable Threat To Patient Safety, Chhaya Gupta, Shakti Shishodia, Pallavi Sehgal, Deborah Eke
URGENT Matters
No abstract provided.
Self-Prescribed Antibiotics Before The Ed Visit: A Hidden Driver Of Antimicrobial Resistance In Acute Gastroenteritis, Rohan Sahebrao Baviskar, Saloni Paranjape, Gurbachan Singh, Mallika Manyapu
Self-Prescribed Antibiotics Before The Ed Visit: A Hidden Driver Of Antimicrobial Resistance In Acute Gastroenteritis, Rohan Sahebrao Baviskar, Saloni Paranjape, Gurbachan Singh, Mallika Manyapu
URGENT Matters
No abstract provided.
Beyond Visual Inspection: Evaluating The Role Of Borescope Technology In Detecting Internal Contamination Of Reprocessed Surgical Instruments, Charlotte Annes, Adrienne Bell Bba, Cspdt, Robin Tannous Bsn, Rn, Cnor, Jonathan T. Berback Mph, Cic
Beyond Visual Inspection: Evaluating The Role Of Borescope Technology In Detecting Internal Contamination Of Reprocessed Surgical Instruments, Charlotte Annes, Adrienne Bell Bba, Cspdt, Robin Tannous Bsn, Rn, Cnor, Jonathan T. Berback Mph, Cic
Research Scholars
No abstract provided.
How Christians Get "Calling" Wrong, David J. Mulder
How Christians Get "Calling" Wrong, David J. Mulder
Faculty Work Comprehensive List
"How can you faithfully follow Jesus, using what God has given you to joyfully work towards addressing... broken places?"
Posting about Christian vocation from In All Things, a blog which highlights the shared faithful and orthodox Reformed Christian perspective of our writers, exploring how to fearlessly engage with every aspect of modern life—until all is made new.
How Christians Get "Calling" Wrong
Utilizing Data To Inform Educational Decision Making, Andrew Blum, Kerri Green Edd, Ms
Utilizing Data To Inform Educational Decision Making, Andrew Blum, Kerri Green Edd, Ms
Research Scholars
No abstract provided.
Can Machines Testify? Llms And The Boundaries Of Testimonial Epistemology, Michael J. Cummins
Can Machines Testify? Llms And The Boundaries Of Testimonial Epistemology, Michael J. Cummins
Philosophy Summer Fellows
As Large Language Models and AI chatbots become increasingly prevalent, pressing questions are raised about whether beliefs formed through LLM interactions carry the same epistemic weight as beliefs formed through human testimony. How we answer this question depends on whether LLMs can function as testifiers, a role which is typically assumed to require a human or human-like agent. This assumption has gone largely unexamined, yet its consequences are significant: if LLM outputs cannot constitute testimony, then the justificatory tools of testimonial epistemology are unavailable to any beliefs formed through LLM interaction. This paper challenges that assumption. It first argues that …
Dnp Final Report: Improving Length Of Stay Outcomes Using Structured Barrier Rounds: A Quality Improvement Project, Martha Kwamboka Apella
Dnp Final Report: Improving Length Of Stay Outcomes Using Structured Barrier Rounds: A Quality Improvement Project, Martha Kwamboka Apella
DNP Final Reports
Prolonged length of stay (LOS) in the acute care setting is a challenging issue driven by multiple factors. Increased LOS is associated with mortality, hospital-acquired infections, patient safety events, functional impairment, decreased quality of life, social isolation, and increased cost of care. The causes of increased LOS in the medical-surgical unit are unclear, necessitating an evidence-based project to address the problem. The purpose of this quality improvement initiative was to implement structured interdisciplinary barrier rounds and evaluate their effect on LOS, opportunity days, and estimated cost of care in a medical-surgical unit. The facility complex care coordinator (CCC) was identified …
The Hidden Strategy Behind Trump’S Latest Canada Tariffs, Marc L. Busch, Barry Appleton
The Hidden Strategy Behind Trump’S Latest Canada Tariffs, Marc L. Busch, Barry Appleton
Other Publications
No abstract provided.
Care Down Syndrome: Responding To An Unmet Need, Brian Chicoine, Dana Sciullo, Laura Krohn, Amanda Zhang, Margot Rhondeau, Jessica Kuss
Care Down Syndrome: Responding To An Unmet Need, Brian Chicoine, Dana Sciullo, Laura Krohn, Amanda Zhang, Margot Rhondeau, Jessica Kuss
Advocate GME
No abstract provided.
Risk And Timing Of Age-Related And Other Conditions In Individuals With Down Syndrome, Hannah Tavalire, Akaninyene I. Noah, Veronica Fitzpatrick, Hannah Graham, Shelly Verma, Laura Krohn, Daniel Vockeroth, Brian Chicoine
Risk And Timing Of Age-Related And Other Conditions In Individuals With Down Syndrome, Hannah Tavalire, Akaninyene I. Noah, Veronica Fitzpatrick, Hannah Graham, Shelly Verma, Laura Krohn, Daniel Vockeroth, Brian Chicoine
Advocate GME
No abstract provided.
Is Originalism Orthodoxy?, Neel Sukhatme
Is Originalism Orthodoxy?, Neel Sukhatme
Articles
What theory of constitutional interpretation has the Supreme Court followed? We search Supreme Court opinions for a wide range of sources that originalists identify as central to their methodology, over the entire universe of cases beginning in 1791. We find that for much of Supreme Court history, conventional indicators of originalist practice--citations to Founding-era sources--are largely absent, raising questions about originalism's past orthodoxy. Originalist citation practices are absent for much of the 19th century and grow sharply in the late 20th century. The Article elaborates the implications of these findings for debates in constitutional law.
Sammy Group Llc V. Collins
All Decisions
After trial on the tenant's counterclaims of breach of warranty of habitability, harassment, and rent overcharge, the court entered judgment for the tenant on all three. The subject apartment was found to be an unlawful combination of predecessor apartments whose legal rent was never registered with DHCR, requiring application of the default formula under RSC § 2522.6(b)(3) to calculate overcharge damages. The court awarded a rent abatement, civil penalties for harassment, and entered an order enjoining the landlord from further harassing the tenant.
Keeping Local Produce Safe: N.H. Farmers Get Assistance From Extension, Adam Drapcho
Keeping Local Produce Safe: N.H. Farmers Get Assistance From Extension, Adam Drapcho
UNH Today Archive
No abstract provided.
Raymond Rodriguez V. Loyal Source Government Services
Raymond Rodriguez V. Loyal Source Government Services
2026 Decisions
USDC for the Middle District of Pennsylvania
Dupilumab For Patients With Allergic Fungal Rhinosinusitis, Amber U Luong, Joshua M Levy, Sarah K Wise, Joseph K Han, Mamoru Yoshikawa, Luo Zhang, Rodney Schlosser, Prerna Ranganathan, Paula Dakin, Jennifer Maloney, George D Yancopoulos, Andrew P Fontenot, Neelam A Phadke, Lacey R Robinson
Dupilumab For Patients With Allergic Fungal Rhinosinusitis, Amber U Luong, Joshua M Levy, Sarah K Wise, Joseph K Han, Mamoru Yoshikawa, Luo Zhang, Rodney Schlosser, Prerna Ranganathan, Paula Dakin, Jennifer Maloney, George D Yancopoulos, Andrew P Fontenot, Neelam A Phadke, Lacey R Robinson
The Brown Foundation: Institute of Molecular Medicine
Background: Allergic fungal rhinosinusitis (AFRS) is a severe subtype of chronic rhinosinusitis characterized by fungal hypersensitivity and accentuated type 2 inflammation. Dupilumab-a fully human mAb blocking IL-4/13, approved for type 2 inflammatory diseases, including chronic rhinosinusitis with nasal polyps-may benefit patients with AFRS.
Objective: We sought to understand the effect of dupilumab in AFRS.
Methods: In this phase 3 trial, patients with AFRS age ≥6 years were randomized to dupilumab or matched placebo for 52 weeks. The primary end point was Lund-Mackay computed tomography score, quantifying sinus opacification, at 52 weeks. Secondary end points were multiplicity-controlled and hierarchically tested.
Results: …
Effects Of Non-Surgical Periodontal Therapy On Dental Plaque Microbiome, Qingguo Wang, Bing-Yan Wang, Derek Wilus, Hua Xie
Effects Of Non-Surgical Periodontal Therapy On Dental Plaque Microbiome, Qingguo Wang, Bing-Yan Wang, Derek Wilus, Hua Xie
Faculty, Staff and Student Publications
Periodontitis, a chronic inflammatory disease affecting approximately 40% of U.S. adults aged 30 years and older, is characterized by dysbiosis of the dental plaque microbiome. However, although scaling and root planing (SRP) is the cornerstone of periodontal treatment, its effects on the taxonomic composition and functional potential of the dental plaque microbiome remain incompletely understood. In this study, we used whole-metagenome shotgun sequencing to characterize taxonomic composition and functional potential in dental plaque microbiomes collected from 39 patients with Stage II or III generalized periodontitis before and 3–4 months after SRP. Consistent with clinical improvement, periodontal therapy significantly reduced probing …
Entity Labels Are Not Entity Signals: A Framework For Observable Relevance In Document Re-Ranking, Utshab Kumar Ghosh, Shubham Chatterjee
Entity Labels Are Not Entity Signals: A Framework For Observable Relevance In Document Re-Ranking, Utshab Kumar Ghosh, Shubham Chatterjee
Computer Science Faculty Research & Creative Works
Entity-aware document retrieval uses query-associated entities as ranking signals, assuming that semantically relevant entities are also useful retrieval signals. We show this assumption is insufficient - and explain why. Unlike terms, which are ground-truth observations, entity links are hypotheses produced by an imperfect linker: an entity can be topically central yet provide no discriminative signal if the linker fires indiscriminately across relevant and non-relevant documents. We formalize this as a distinction between Conceptual Entity Relevance (CER) - whether an entity is topically related to a query - and Observable Entity Relevance (OER) - whether its observed presence in a collection …
La\'Keya Keo V. Wellspan York Hospital
La\'Keya Keo V. Wellspan York Hospital
2026 Decisions
USDC for the Middle District of Pennsylvania
Reseña Del Libro Introducción Al Estudio Del Discurso Digital En Español, De M. E. Placencia Y A. Parini (Eds.) (2024), New York: Routledge, David Sanchez-Jimenez
Reseña Del Libro Introducción Al Estudio Del Discurso Digital En Español, De M. E. Placencia Y A. Parini (Eds.) (2024), New York: Routledge, David Sanchez-Jimenez
Publications and Research
Se trata de una reseña del libro Introducción al estudio del discurso digital en español, editado por M. E. Placencia y A. Parini
Availability Of Cannabinoid-Infused Products In Corner Stores In Franklin Park, Allentown, Abigale Brosious, Joselyn Correa-Melendez Dhsc, Mph, Kimberly C. Brown Md
Availability Of Cannabinoid-Infused Products In Corner Stores In Franklin Park, Allentown, Abigale Brosious, Joselyn Correa-Melendez Dhsc, Mph, Kimberly C. Brown Md
Research Scholars
No abstract provided.