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Policy Design Complexity And Policy Outputs: Theory And Methods, Brandon Charles, Saba Siddiki, Matia Vannoni, Christopher Frantz, Nicholas Oesterling Jul 2026

Policy Design Complexity And Policy Outputs: Theory And Methods, Brandon Charles, Saba Siddiki, Matia Vannoni, Christopher Frantz, Nicholas Oesterling

Center for Policy Design and Governance

This brief summarizes "Policy design complexity and policy outputs: Theory and methods," co-authored by Brandon Charles, Saba Siddiki, Matia Vannoni, Christopher Frantz, and Nicholas Oesterling in Policy Design and Practice.


Thermoclock:A Novel Automated Temperature Regulation Device That Can Model Circadian Entrainment And Disruption In 2d And 3d In Vitro Models, Kaiyin Kelly Zhang, Cathryn A. Cutia, Chanelle A. Moise, Bhavna Kalyanaraman, Kaitlyn Chhe, Jiexin Wang, Michelle E. Farkas, Ilia N. Karatsoreos, Mary Harrington, Meghan E. Huber, Cathal J. Kearney Jul 2026

Thermoclock:A Novel Automated Temperature Regulation Device That Can Model Circadian Entrainment And Disruption In 2d And 3d In Vitro Models, Kaiyin Kelly Zhang, Cathryn A. Cutia, Chanelle A. Moise, Bhavna Kalyanaraman, Kaitlyn Chhe, Jiexin Wang, Michelle E. Farkas, Ilia N. Karatsoreos, Mary Harrington, Meghan E. Huber, Cathal J. Kearney

Biological Sciences: Faculty Publications

Circadian rhythms are critical for maintaining homeostasis and regulating physiological functions, and consequentially impact disease progression; yet, they remain largely overlooked in in vitro models used in preclinical research. One major barrier to rigorously testing the role of circadian rhythms in these models is the lack of accessible tools that seamlessly integrate into standard culture setups and are capable of sustainably delivering time cues to cells and tissues in long term experiments. Here, we present the ThermoClock, a low-cost, Arduino-based automated temperature control system capable of delivering independent temperature programs to multiple cultures simultaneously. Using circadian reporter U2OS cell lines …


A Prospective Study Of Hyperspectral Imaging For Lower Extremity Tissue Assessment In Normative And At-Risk Populations, Jessica Sima, Mariana Rodriguez, Stephanie Campbell, Amanda Killeen Jul 2026

A Prospective Study Of Hyperspectral Imaging For Lower Extremity Tissue Assessment In Normative And At-Risk Populations, Jessica Sima, Mariana Rodriguez, Stephanie Campbell, Amanda Killeen

School of Podiatric Medicine - Student Research

Introduction:  Diabetic foot ulceration and peripheral vascular disease remain major causes of morbidity and limb loss, yet early identification of tissue compromise can be challenging, particularly across diverse skin tones. Hyperspectral imaging (HSI) is a non-invasive technology that quantifies tissue oxygenation by measuring the absorption and reflection of near-infrared light.

The objective of this study is to evaluate the relationship between oxygenation, skin tone, skin temperature, and ambient skin temperature in adults with and without risks of foot ulcers.

Method: This ongoing prospective observational study recruits English- and Spanish-speaking adults aged 18 and over from campus, clinics, and community outreach …


State Investments In Childcare In The Mountain West, 2026, Sophia Booth, Yiselle Olivas Ruiz, Caitlin J. Saladino, William E. Brown Jr. Jul 2026

State Investments In Childcare In The Mountain West, 2026, Sophia Booth, Yiselle Olivas Ruiz, Caitlin J. Saladino, William E. Brown Jr.

Economic Development & Workforce

This fact sheet presents data on state investments in childcare and preschool programs in the five Mountain West states of Arizona, Colorado, Nevada, New Mexico, and Utah. BabyCenter’s 2026 analysis, “These are the best and worst states for childcare,” includes state-level data on childcare accessibility, affordability, public investment, and overall childcare rankings for all 50 states. This fact sheet focuses on childcare spaces per child, income spent on childcare, and state investment per child.


The Role Of Mitochondria In The Pathogenesis Of Parkinson’S Disease, Oyinkansola Mudasiru, Vivian Etugbo, Bhuvana Lakkasetter, Claudia Biguetti, Reginald Adiele Jul 2026

The Role Of Mitochondria In The Pathogenesis Of Parkinson’S Disease, Oyinkansola Mudasiru, Vivian Etugbo, Bhuvana Lakkasetter, Claudia Biguetti, Reginald Adiele

School of Podiatric Medicine - Student Research

Introduction: Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by the degeneration of the dopaminergic neurons of the substantia nigra that leads to motor and non-motor dysfunctions. Emerging evidence highlights mitochondrial dysfunction as a key factor in PD pathogenesis. This project aims to investigate the pathophysiology of PD, highlighting the involvement of oxidative stress, and examining current and emerging therapeutic approaches aimed at restoring mitochondrial function.

Methodology: A systematic literature review was conducted using PubMed and Google Scholar within the 2004-2024 date range. Keywords included “Parkinson’s disease”, “mitochondrial dysfunction", “oxidative stress”, and neurodegeneration”. Data was extracted regarding …


Pennsylvania Game Commission V. Thomas E Proctor Heirs Trust Jul 2026

Pennsylvania Game Commission V. Thomas E Proctor Heirs Trust

2026 Decisions

USDC for the Middle District of Pennsylvania


Estimated Prebiotic Intake And Depression In Us Adults: Repeated Cross-Sectional Analyses Of Nhanes 2015–2018 And 2021–2023, Cassandra Boyd, John Gieng Jul 2026

Estimated Prebiotic Intake And Depression In Us Adults: Repeated Cross-Sectional Analyses Of Nhanes 2015–2018 And 2021–2023, Cassandra Boyd, John Gieng

Faculty Research, Scholarly, and Creative Activity

Prebiotics are selectively utilised dietary substrates that may influence depression through gut microbiota-related pathways, but population-level estimates of intake and associations with depression are limited. This repeated cross-sectional study estimated intake of International Scientific Association for Probiotics and Prebiotics (ISAPP)-recognised prebiotics and examined associations with depression among US adults using National Health and Nutrition Examination Survey (NHANES) 2015–2018 and NHANES August 2021–August 2023, analysed as independent survey periods. Estimated intakes of galactooligosaccharides and inulin-type fructans were assigned to foods using published source-food values, Food and Nutrient Database for Dietary Studies food codes, and ingredient-level information for mixed dishes. Depression was …


Integrating Georeferencing And Fire Anatomy Modeling In Canyon Fire Experiments Using Thermal Uav Remote Sensing, Xiangyu Ren, Bo Yang, Alexander I. Filkov, Katherine M. Wilkin, C. David Benterou, Owen Hussey, Craig B. Clements Jul 2026

Integrating Georeferencing And Fire Anatomy Modeling In Canyon Fire Experiments Using Thermal Uav Remote Sensing, Xiangyu Ren, Bo Yang, Alexander I. Filkov, Katherine M. Wilkin, C. David Benterou, Owen Hussey, Craig B. Clements

Faculty Research, Scholarly, and Creative Activity

Background: Wildfires profoundly impact ecosystems and human health, making them a critical research focus. Drone-mounted Thermal Infrared (TIR) sensors are widely used for active fire monitoring due to their ability to penetrate smoke and capture real-time fire dynamics. Aims: This study addresses the challenges of georeferencing TIR data accurately, caused by limited fire anatomy modeling, imprecise georeferencing, the coarse resolution of TIR imagery and the dynamic nature of fire behavior. Methods: We collected a one-hour TIR dataset capturing a fast-moving controlled fire in a California canyon, US, alongside auxiliary data of multispectral and in situ meteorological observations. We developed an …


Chemurgy 2.0 Data Science, Dylan Bock, Ratul Chowdhury, Ali Tabei, William Harwood, Aleksandar Poleksic Jul 2026

Chemurgy 2.0 Data Science, Dylan Bock, Ratul Chowdhury, Ali Tabei, William Harwood, Aleksandar Poleksic

Faculty Publications

No abstract provided.


Sustainable Organic Materials Used In The Construction Sector, Michael P. Wistuba, Di Wang, Chiara Riccardi, Libo Yan, Zhanping You, Lily D. Poulikakos, Ana Jiménez Del Barco Carrión Jul 2026

Sustainable Organic Materials Used In The Construction Sector, Michael P. Wistuba, Di Wang, Chiara Riccardi, Libo Yan, Zhanping You, Lily D. Poulikakos, Ana Jiménez Del Barco Carrión

Michigan Tech Publications

No abstract provided.


Javaid V. 1129 59 Lofts Llc Jul 2026

Javaid V. 1129 59 Lofts Llc

All Decisions

Tenants displaced from their rent-stabilized apartment by fire were restored to possession after more than two years. Despite renting another apartment during displacement, the court found no surrender because no surrender agreement or payment ever materialized. The court held that failure to file a rent reduction order when the unit became uninhabitable does not constitute abandonment of the tenancy. The court declined to weigh the equities in favor of third-party tenants currently in the apartment, one of whom never appeared and the other failed to present testimony justifying why they should not vacate.


Healer Or Human? How Online Physician Reviews Guide Patient Choice, Shabnam Azimi, Sina Ansari, Ignacio Luri, Atefeh Yazdanparast Jul 2026

Healer Or Human? How Online Physician Reviews Guide Patient Choice, Shabnam Azimi, Sina Ansari, Ignacio Luri, Atefeh Yazdanparast

Faculty Publications

Online reviews increasingly guide physician choice, yet it remains unclear whether content emphasizing a physician's competence (technical skills) or benevolence (prioritizing patients' welfare over self‐interest) more strongly influences patients' decisions. Integrating a field study of 12,351 physician reviews with two online experiments, we distinguish two dimensions of review effectiveness: how helpful readers find a review, and how confident they feel about the choice it informs. We show that competence‐ and benevolence‐focused content influences these outcomes through distinct mechanisms. Benevolence‐focused reviews receive higher helpfulness evaluations because caring behaviors are easier to describe in concrete, vivid language and because naturalistic review platforms …


Usa V. Gregory Turbe Jul 2026

Usa V. Gregory Turbe

2026 Decisions

USDC for the District Court of the Virgin Islands


Las Exposiciones Temporales De Cristóbal Balenciaga (2015-2022), Julio González Liendo, Trilce Navarrete Hernández Jul 2026

Las Exposiciones Temporales De Cristóbal Balenciaga (2015-2022), Julio González Liendo, Trilce Navarrete Hernández

Artículos científicos

Este estudio realiza un análisis comparativo y retrospectivo de las estrategias de comunicación utilizadas para promocionar las exposiciones temporales de Cristóbal Balenciaga entre 2015 y 2022. Los elementos utilizados en sus planes de comunicación se identificaron mediante entrevistas semiestructuradas con los directores de comunicación de 16 espacios expositivos internacionales y con el director de comunicación del Cristóbal Balenciaga Museoa. El análisis reveló que los museos no emplean estrategias transmedia, lo que se traduce en una política de comunicación unilateral que limita la participación en redes sociales y el compromiso con la narrativa de las exposiciones. La falta de una estrategia …


Enhanced Transdermal Immunization Via Solid-In-Oil Nanodispersions Incorporating Dendritic Cell-Targeting Peptide, Md Samiul Islam, Md. Shahin Ekka Sarker, Yoshirou Kawaguchi, Rie Wakabayashi, Noriho Kamiya, Muhammad Moniruzzaman, Masahiro Goto Jul 2026

Enhanced Transdermal Immunization Via Solid-In-Oil Nanodispersions Incorporating Dendritic Cell-Targeting Peptide, Md Samiul Islam, Md. Shahin Ekka Sarker, Yoshirou Kawaguchi, Rie Wakabayashi, Noriho Kamiya, Muhammad Moniruzzaman, Masahiro Goto

Publications and Research

Transdermal immunization represents a promising needle-free alternative to conventional vaccination. However, efficient antigen delivery and robust immune activation remain major challenges. In this study, a solid-in-oil (S/O) nanodispersion system comprising a dendritic cell-targeting peptide (HR8), ovalbumin (OVA), and an adjuvant was developed for transdermal immunization. The HR8 peptide along with OVA was successfully incorporated into an S/O nanodispersion with an optimal hydrodynamic diameter of particles (< 200 nm) and exhibited stable physical properties for up to 90 days. In vitro and in vivo studies demonstrated enhanced antigen delivery with insignificant skin irritation in C57BL/6N mice. Moreover, in vivo transdermal immunization studies demonstrated that the addition of the HR8 peptide enhanced OVA-specific IgG responses (~1.5-fold). Notably, the HR8 peptide also promoted an approximately 2.5-fold increase in IgG2c levels, suggesting a shift toward a more T helper type 1-biased immune response, as reflected by an increased IgG2c/IgG1 ratio. Overall, these findings demonstrate that the incorporation of HR8 peptide into an S/O nanodispersion enables efficient transdermal antigen delivery and improved immunogenicity, highlighting its potential as a simple, non-invasive, and patient-friendly immunization strategy.


City Branding. Estrategias Y Propósitos En La Escenificación De La Ciudad, Verónica Meléndez Valoria Jul 2026

City Branding. Estrategias Y Propósitos En La Escenificación De La Ciudad, Verónica Meléndez Valoria

Artículos científicos

Las ciudades, especialmente en su desarrollo de los últimos cien años, han sido objeto de múltiples propósitos, convertidas en demostraciones de poder, símbolos de progreso e innovación, motores económicos y ensayos de nuevas formas de vida urbana.En tiempos recientes, el concepto de city brandingha introducido un cambio clave: la ciudad no es solo un soporte físico, sino portadora de una identidad propia o proyectada. Esto trasciende ciertos atributos tangibles —edificios, fachadas, diseño urbano—e invita a considerar dimensiones culturales, sociales y simbólicas. Este enfoque plural resulta relevante ante la previsión de crecimiento de las megaciudades, la preferencia por la ciudad, y …


Where Do Ai Coding Agents Fail? An Empirical Study Of Failed Agentic Pull Requests In Github, Ramtin Ehsani, Sakshi Pathak, Shriya Rawal, Abdullah Al Mujahid, Mia Mohammad Imran, Preetha Chatterjee Jul 2026

Where Do Ai Coding Agents Fail? An Empirical Study Of Failed Agentic Pull Requests In Github, Ramtin Ehsani, Sakshi Pathak, Shriya Rawal, Abdullah Al Mujahid, Mia Mohammad Imran, Preetha Chatterjee

Computer Science Faculty Research & Creative Works

AI coding agents are now submitting pull requests (PRs) to software projects, acting not just as assistants but as autonomous contributors. As these agentic contributions are rapidly increasing across real repositories, little is known about how they behave in practice and why many of them fail to be merged. In this paper, we conduct a large-scale study of 33k agent-authored PRs made by five coding agents across GitHub. (RQ1) We first quantitatively characterize merged and not-merged PRs along four broad dimensions: 1) merge outcomes across task types, 2) code changes, 3) CI build results, and 4) review dynamics. We observe …


Prehospital Flumazenil: Five-Year Review Of Use, Indications, Outcomes, And Adverse Events In Suspected Benzodiazepine Overdose, Cameron G. Hanson, Bryan P. Beaver, Eric Frantz, Thomas Dunn, Stephen Thornton, Isabel Cava, Ryan C. Jacobsen Jul 2026

Prehospital Flumazenil: Five-Year Review Of Use, Indications, Outcomes, And Adverse Events In Suspected Benzodiazepine Overdose, Cameron G. Hanson, Bryan P. Beaver, Eric Frantz, Thomas Dunn, Stephen Thornton, Isabel Cava, Ryan C. Jacobsen

Student Publications

Introduction: Historically, flumazenil was employed as both a diagnostic aid in unresponsive patients and as an antidote for suspected benzodiazepine overdose in both emergency departments and out-of-hospital settings. However, its prehospital application has been historically constrained by long-standing concerns regarding adverse events, leading many emergency medical service (EMS) systems to restrict or avoid its use. The use of flumazenil in the prehospital setting remains underreported in the literature, despite its inclusion in the treatment protocols of various EMS agencies. We conducted a descriptive analysis of the use of flumazenil by EMS in the out-of-hospital setting across the state of Kansas …


Cardozo Law News Brief: July 31, 2026, Benjamin N. Cardozo School Of Law Jul 2026

Cardozo Law News Brief: July 31, 2026, Benjamin N. Cardozo School Of Law

Cardozo Law News Briefs

Highlights from the July 10, 2026 Cardozo Law News Brief include:

  • Interim Dean of Students Francesca Acocella received the National Association of Law Student Affairs Professionals’ (NALSAP) Core Four Award in recognition of her outstanding contributions to law student affairs.
  • Professor Jessica Roth spoke to Bloomberg about the Supreme Court’s Cook, Slaughter, and birthright citizenship decisions, discussing their implications for the Fourteenth Amendment.
  • Professor Michael Pollack was quoted in Bloomberg about the legal history of sidewalks and responsibilities for their maintenance, and also appeared on CNN to discuss a viral story about community sidewalk construction.
  • Adjunct Professor Gary …


2026 Final Unreclaimed Sites Quality Assurance Project Plan (Qapp), Pioneer Technical Services, Inc. Jul 2026

2026 Final Unreclaimed Sites Quality Assurance Project Plan (Qapp), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


Final Insufficiently Reclaimed Sites Quality Assurance Project Plan (Qapp), Pioneer Technical Services, Inc. Jul 2026

Final Insufficiently Reclaimed Sites Quality Assurance Project Plan (Qapp), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


452 City Island Llc V. Avila Jul 2026

452 City Island Llc V. Avila

All Decisions

In this nonpayment proceeding, Respondent moved to dismiss on the ground that the building was occupied in violation of the Multiple Dwelling Law because an illegal basement apartment had been created without a permit, and two DOB violations issued in 2009 remained open. The court granted the motion, holding that where a building has been altered so that the I-card is no longer accurate, MDL § 302's rent-collection bar is automatically triggered and the landlord's discontinuation of the illegal occupancy is insufficient to cure the violation.


Technical Disclosure Specification: Biomimetic Dermal Magnetohydrodynamic Venting And High-Frequency Metric Strain Transmutation Boundaries, Christopher L. Eckes Jul 2026

Technical Disclosure Specification: Biomimetic Dermal Magnetohydrodynamic Venting And High-Frequency Metric Strain Transmutation Boundaries, Christopher L. Eckes

Defensive Publications Series

This specification formalizes the engineering parameters for a non-mechanical, biomimetic fluidic transport and non-equilibrium thermal boundary layer.

Traditional deep-space vessels treat external plasma shocks and the absolute-zero vacuum as destructive vectors that must be blocked via heavy material bulk. This architecture uses a scale-invariant fluid-substrate approach modeled after microscopic marine dermal structures (vortex attachment denticles).

By embedding a conformal, high-frequency magneto-acoustic micro-transducer array beneath a segmented porous hull, the system drives an effusing hydrogen plasma glove into a series of surface-bound, trailing helical micro-vortices. Instead of venting this mass wastefully into the vacuum, a rhythmic, 4-phase asymmetric

"Heartbeat" phase-shift protocol …


Gci #288: Ultra — Vortex-Aqueous "Mechanic's Battery" V5.0 (Planetary Standard) Complete Engineering Specification For Trash-Derived, Self-Healing Energy Storage, Michael Victor Caldwell Mr. Jul 2026

Gci #288: Ultra — Vortex-Aqueous "Mechanic's Battery" V5.0 (Planetary Standard) Complete Engineering Specification For Trash-Derived, Self-Healing Energy Storage, Michael Victor Caldwell Mr.

Defensive Publications Series

The GCI #288: ULTRA v5.0 is the definitive open-hardware battery architecture, replacing toxic lead-acid and expensive lithium systems with a trash-derived graphene, citric-salt electrolyte, and monolithic 3D-printed vortex case. This version provides the complete engineering data (voltages, concentrations, dimensions) required for immediate fabrication.

Performance Targets:

  • Cost: <$10/kWh (verified BOM).

  • Cycle Life: 5,000+ cycles (via Laponite dendrite suppression).

  • CCA: 22% higher than lead-acid (via J-Groove vortex scrubbing).

  • Safety: Non-toxic, non-flammable, operational at -60°C.


Capacity-Based Lacp Signaling For Proportional Traffic Distribution In Multi-Chassis Link Aggregation, Anonymous Jul 2026

Capacity-Based Lacp Signaling For Proportional Traffic Distribution In Multi-Chassis Link Aggregation, Anonymous

Defensive Publications Series

Systems and methods optimize link aggregation hashing in a Multi-Chassis Link Aggregation (MC-LAG) topology in which a Customer Equipment (CE) device is dual-homed to a plurality of Provider Edge (PE) devices. Each PE device determines a capacity value representing its effective forwarding capacity, based on dynamic health metrics including core-facing Network-to-Network Interface (NNI) bandwidth, and encodes the capacity value in an optional Type-Length-Value (TLV) object carried in Link Aggregation Control Protocol Data Units (LACPDUs). The CE device parses the capacity value for each member link and programs an egress hashing engine to perform weighted load balancing, distributing flows across the …


Technical Disclosure: A Framework For Multiphase Magnetohydrodynamic And Torsional Soliton Shielding Architecture, Christopher L. Eckes Jul 2026

Technical Disclosure: A Framework For Multiphase Magnetohydrodynamic And Torsional Soliton Shielding Architecture, Christopher L. Eckes

Defensive Publications Series

Current spacecraft shielding paradigms rely heavily on passive mass blocking, which imposes severe mass penalties and introduces dangerous secondary nucleon scattering. This paper formalizes a systematic, geometric approach to active spacecraft defense by treating the spacecraft hull, internal fluid layers, and the surrounding vacuum as a single, continuous-density oscillator matrix.

The framework is bifurcated based on operational requirements into a Segmented Air-Gap Cascading Shield with active degaussing coils for crewed configurations (Module 1A) and a lightweight Solid-State Hardening Enclosure for automated uncrewed platforms (Module 1B). Middle-layer active mitigation utilizes high-frequency Circularly Polarized Microwaves (CPM) matched to a high-performance Rogers RT/duroid® …


Ai Agent Token Generation Based On Dynamic Context, Som Madhab Bhattacharya, Surendra Vyas Jul 2026

Ai Agent Token Generation Based On Dynamic Context, Som Madhab Bhattacharya, Surendra Vyas

Defensive Publications Series

A method is disclosed. The method includes receiving, by computer including a coordination module, a request to obtain a token and then providing, by the coordination module to a processing network computer comprising a context analysis engine, a request for historical data associated with a specific set of interactions. The method also includes receiving, by the coordination module, the historical data or data derived from the historical data, and determining, by the coordination module, parameters associated with the token based on the historical data or the data derived from the historical data. The method further includes providing, by the coordination …


Detection-Conditional Multi-Agent Adversary Emulation With Autonomous Evasion-Variant Technique Substitution, Amit Singh Jul 2026

Detection-Conditional Multi-Agent Adversary Emulation With Autonomous Evasion-Variant Technique Substitution, Amit Singh

Defensive Publications Series

Proposed herein is an automated adversary-emulation (red-team) system that executes techniques mapped to the MITRE Adversarial Tactics, Techniques, and Common Knowledge (ATT&CK) framework through a live execution engine and adapts in real time based on whether each technique is detected by the target's defenses. The system combines three elements: a standardized agent context protocol used as an orchestration bus that exposes shared execution state and callable tools to role-specialized reasoning agents; real-time ingestion of endpoint detection and response (EDR), security information and event management (SIEM), and intrusion detection system (IDS) signals as structured inputs to agent reasoning; and detection-conditional, autonomous …


Device Configuration Memory Bridge With Optional Encryption For Serving Multiple Subtending Devices From A Central Non-Volatile Store, Anonymous Jul 2026

Device Configuration Memory Bridge With Optional Encryption For Serving Multiple Subtending Devices From A Central Non-Volatile Store, Anonymous

Defensive Publications Series

A device configuration memory bridge serves firmware and configuration data to multiple subtending devices on a circuit pack from a single central non-volatile storage device. The bridge, implemented in a programmable logic device, terminates each serial configuration interface and emulates the memory that the device expects, translating each transaction into a read from the central device. High-rate bursts are buffered and delivered at the lower interface rate, allowing concurrent servicing at power-on. A host port lets the host processor load files and share the storage device as its own primary storage. Loads are optionally stored encrypted and decrypted on the …


Process For The Preparing Lazertinib Mesylate, Msn Laboratories Private Limited, R&D Center, Hyderabad, India, Srinivasan Thirumalai Rajan, Sagyam Rajeshwar Reddy, Mohammad Rafee Shaik, Buvanagiri Ajay Kumar Jul 2026

Process For The Preparing Lazertinib Mesylate, Msn Laboratories Private Limited, R&D Center, Hyderabad, India, Srinivasan Thirumalai Rajan, Sagyam Rajeshwar Reddy, Mohammad Rafee Shaik, Buvanagiri Ajay Kumar

Defensive Publications Series

The present invention provides process for the preparation of N-[5-[[4-[4-[(dimethyl amino)methyl]-3-phenyl-1H-pyrazol-1-yl]pyrimidin-2-yl]amino]-4-methoxy-2-(morpholin-4-yl)phenyl]acrylamide mesylate represented by the following structural formula-I.