Digital Commons Network^™

Predictors Of Adalimumab Durability In Hidradenitis Suppurativa: A Multicenter Cohort Study, Albert T. Young, Arashleen Pannu, Alexander Velaoras, Roland Leyson, Rayad B. Shams, Alexandra Turfe, Andrea Dai, Mohsen Mokhtari, Sarah Bassett, Joshua Vazhappilly, Richard W. Hass, Iltefat Hamzavi, Christopher J. Sayed, Qing-Sheng Mi, Sherry Yang

Department of Dermatology and Cutaneous Biology Faculty Papers

BACKGROUND: Adalimumab is widely used for hidradenitis suppurativa (HS), but treatment durability varies and predictors of sustained benefit remain uncertain.

OBJECTIVE: To identify clinical and laboratory factors associated with adalimumab treatment durability in HS.

METHODS: We retrospectively studied 135 adults with HS who initiated adalimumab as first biologic therapy across three academic centers from 2013 to 2023. Outcomes were categorized as primary failure (12-24 weeks), secondary failure (24 weeks-2 years), or sustained response (>2 years) based on discontinuation for inefficacy. Predictors of treatment durability were evaluated using ordinal logistic regression.

RESULTS: In univariable analyses, Hurley stage 3, higher body …

Draft Final 2023 Reclamation Improvement Sites Sampling: Bres No. 17 – Paymaster Dump Site Evaluation Summary Report, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

This Butte Priority Soils Operable Unit (BPSOU) Reclamation Improvement (RI) Site Evaluation Summary Report (SESR) presents results of soil sampling conducted on October 11, 2023, at the Butte Reclamation Evaluation System (BRES) No. 17 – Paymaster Dump Site and adjacent areas (referred to herein as Site) within the BPSOU. The BPSOU Consent Decree (CD) (referred to herein as BPSOU CD; EPA, 2020) Appendix D, Attachment C Further Remedial Elements Scope of Work (FRESOW) prescribed further evaluation of sites reclaimed prior to establishment of the Butte Hill Revegetation Specifications (BHRS) (Appendix A to the BPSOU CD), which were initially established in …

Final 2022 Insufficiently Reclaimed Sites Sampling: Bres No. 16 Site Evaluation Summary Report, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

This Butte Priority Soils Operable Unit (BPSOU) Insufficiently Reclaimed (IR) Site Evaluation Summary Report (SESR) presents results of soil sampling conducted on August 12, 2022, at the IR source area Butte Reclamation Evaluation System (BRES) No. 16 – Curry Site and adjacent areas (referred to herein as Site) within the BPSOU. The BPSOU Consent Decree (CD) required further evaluation of this IR Site since reclamation was conducted in 1991, prior to establishment of the Butte Hill Revegetation Specifications (BHRS) (EPA, 2020) and because the Site did not meet BRES requirements during the 2017 assessment performed by the Clark Fork Watershed …

Abnormal Presentation Of An Intra-Abdominal Desmoid Tumor In A Young, Healthy Male: A Case Report, Erica Kozorosky, Konstantina Kostara, Zohaa Ahmad, Benetta Miller, Zbigniew Moszczynski

Student Publications

Desmoid tumors are soft tissue proliferations with a tendency to invade surrounding tissues and, when occurring in the mesentery, can present with obstructive symptoms, pain, or organ damage. This report presents a case of a 33-year-old male with no medical history or contributory family history who developed systemic infectious symptoms related to cystic necrosis of a desmoid tumor. The cystic necrosis suggests that the tumor may have grown so rapidly that it outgrew its vascular supply before causing any symptoms, highlighting the diverse range of presentations and emphasizing individualized treatment plans.

Access And Use Of Agricultural Information Services For Sustainable Irish Potato Production And Socioeconomic Development Among Farmers In Plateau State, Nigeria, Olunusi Patience Abosede Mrs, Fwenshimwa Goyol Yarima Mrs, Oyetunde Adeduntan Olajumoke Adedokun, Olusola Funmilayo Babalola, Segilola Victoria Omowumi

Library Philosophy and Practice (e-journal)

Multi-Agent Autonomous Laboratories, Xavier Pillet

Defensive Publications Series

This document, produced with the assistance of ChatGPT o3, Claude Opus 5 and Gemini 3.6 Reasoning, is released under the Apache License 2.0. It is a voluntary defensive publication (prior art) and therefore enters the prior art upon release under the applicable patent statutes : EPC Art. 54(2) (European Patent Convention), French IPC Art. L 611-11 (French Intellectual Property Code), 35 U.S.C. §102(a) (United States Patent Act), Chinese Patent Law Art. 22(5) (両匡丢氡儡吡嘡丣刡氢), and Japanese Patent Act Art. 29(1) (闘旧避). It releases into the public domain 113 inventions covering autonomous laboratories and their multi-agent artificial intelligence systems: hardware safety and …

Jason Morgan V. Eric Siegfried

2026 Decisions

USDC for the Eastern District of Pennsylvania

Marlowe V. Guzman

2026 Decisions

USDC for the Middle District of Pennsylvania

Jasir Massey-Campbell V. Bridgecrest Acceptance Corp.

2026 Decisions

USDC for the Eastern District of Pennsylvania

Nicole Dubose V. Morrison Healthcare

2026 Decisions

USDC for the Eastern District of Pennsylvania

Peter Cresci V. Timothy Mcnamara

2026 Decisions

USDC for the District of New Jersey

Lucas Francisco-Gonzalez V. Attorney General United States Of America

2026 Decisions

Agency

Usa V. Anthony Bressi

2026 Decisions

USDC for the Middle District of Pennsylvania

Shanthi Hejamadi V. Midland Funding Llc

2026 Decisions

USDC for the District of New Jersey

Draft Hybrid Assembly And Annotation Of The Drosophila Palustris And Drosophila Subpalustris Genomes, William A. Dion, Emily Washeleski, Tessa Steenwinkel, Emily Taylor, Prajakta P. Kokate, Aidan Vandrie, Thomas Werner, Paul Goetsch

Michigan Tech Publications

Species within the quinaria group of the genus Drosophila are models for ecological genetic studies on topics that include morphological diversity, color pattern development, and feeding behavior. Drosophila palustris and Drosophila subpalustris are closely related members within the quinaria species group that differ primarily in subtle morphological and behavioral traits. To support future evolutionary genomic studies in drosophilids, we completed new draft hybrid assemblies and annotations of the D. palustris and D. subpalustris genomes. We obtained a fragmented assembly for D. palustris (N50 = 874 Kb) and a near chromosome-scale D. subpalustris assembly (N50 = 27.5 Mbp). Assembly contiguity, repeat …

Promoting Scientific Impact At The Nih, Fred D. Ledley M.D.

CISI Publication

We are honored to offer our comments on Promoting Scientific Impact at the NIH in response to NOT-OD-26-087: Request for Information on Measuring and Rewarding Scientific Impact.

These comments are informed by my professional experience as the founding director of the Center for Integration of Science and Industry at Bentley University, which has a mission to “advance the translation of scientific discoveries for public value by engaging science, business, and policy in transdisciplinary dialogue, scholarship, and education.” Our approach is to bring together the perspectives of natural science, business, analytics, economics, law, and policy to better understand, and advance, the …

Can The Safety Net Support Families Through Childbirth?, Hyojeong Kim, Colleen Heflin, Taryn Morrissey

Center for Policy Research

Childbirth is a life event that often disrupts maternal employment and household earnings just as family expenses increase. In the United States, families do not have access to a national paid parental leave program and must rely on a patchwork of safety net programs that were not designed specifically to support households during pregnancy and the immediate postpartum period. This brief uses linked administrative data from the Virginia Longitudinal Data System (2016–2021) to describe changes in household earnings and social welfare benefits before and after childbirth among low-income mothers receiving the Supplemental Nutrition Assistance Program (SNAP) or Temporary Assistance for …

08-19-26 Bor Hsc Committee Meeting Agenda, Patricia Serna

HSC Committee (A subcommittee of the UNM Board of Regents)

08-19-26 BOR HSC Committee Meeting Agenda

Oregon State Rank Assessment For Stemmed Polypore (Xeroceps Skamania), Nora Dunkirk

Institute for Natural Resources Publications

Oregon state conservation status assessment for Stemmed Polypore (Xeroceps skamania) using NatureServe methodology, 2026.

Wille Zum Wald: Nietzsche’S Discovery Of Forest Bathing, Gary Shapiro

Philosophy Faculty Publications

In the fourth part of our “The Forest as a Living Foundation” series, the distinguished American Nietzsche scholar Gary Shapiro investigates new angles on Nietzsche’s bonds to the woods: the philosopher’s personal enthusiasm for what is increasingly called “forest bathing,” the science behind how this practice benefits body, mind, and spirit, and the sheer pleasure of breathing fresh air, in woodland and wherever else we can find it. Shapiro’s essay showcases why this particular Lebensraum matters, not just for our individual well-being, but for the health of the entire planet.

Implementation Readiness For National Cancer Survivorship Care Standards, Christiane J. El Khoury, Meera Gupta, Maryem Shirzadi, Heidi Dowst, Martha Mims, Maysa Abu-Khalaf, Hoda Badr

Kimmel Cancer Center Faculty Papers

IMPORTANCE: Cancer survivorship care is a growing public health priority, yet delivery remains variable across health systems. The National Standards for Cancer Survivorship Care provide a framework for high-quality care, but little empirical evidence exists regarding health system readiness to implement these standards in routine practice.

OBJECTIVE: To assess implementation readiness for the National Standards for Cancer Survivorship Care and identify perceived barriers to implementation.

DESIGN, SETTING, AND PARTICIPANTS: This real-time Delphi survey study was conducted from January to March 2025 at a National Cancer Institute-designated comprehensive cancer center. Participants were multidisciplinary experts involved in cancer survivorship care delivery, care …

Nascent Adam17 Synthesis Potentiates Gpibα Cleavage In Resting And Stimulated Stored Platelets, Shayan Askari, Harriet Ghansah, Christopher D. Mansi, Timothy J. Stalker, Lawrence E. Goldfinger

Cardeza Foundation for Hematologic Research

Platelet concentrates stored at room temperature have a shelf life of 5 to 7 days. During storage, platelets undergo glycoprotein cleavage by metalloproteases, notably cleavage of glycoprotein Ibα (GPIbα) by a disintegrin and metalloprotease 17 (ADAM17), which leads to decreased posttransfusion reactivity and recovery. To investigate the putative roles of nascent synthesis of ADAM17 in GPIbα shedding and platelet function during room temperature platelet storage. Human platelets maintained in autologous plasma were treated with naked endonuclease-resistant ADAM17 or control short inhibitory RNA (siRNA) and monitored for molecular and cellular effects during storage. Platelet-specific Adam17-deleted mice were generated, and the dynamics …

No. 114 An Order To Establish The Tennesee Strategic Transportation Accountability Council, Bill Lee

Executive Orders

No abstract provided.

Troutman Street Llc V. Aponte

All Decisions

Court sua sponte dismissed illegal use holdover under CPLR 409(b) because predicate notice of termination failed to specify the statute or regulation on which the termination of the rent stabilized tenancy is based, as required by RSC § 2524.2(b). Every notice to vacate must state the ground under RSC § 2524.3 or 2524.4 upon which the owner relies.

Joseph Herschel Mckissick, Jr. Papers, 1947-2014, Joseph Herschel Mckissick Jr.

Center for Restoration Studies Archives, Manuscripts and Personal Papers Finding Aids

No abstract provided.

Lai V. Wong

All Decisions

Tenant moved to dismiss a holdover proceeding predicated on a 90-day notice of termination, arguing improper service and that landlord's Good Cause Eviction Law notice failed to adequately plead the small landlord exemption from GCEL. The court granted dismissal, holding that the GCEL notice did not provide sufficient specificity to satisfy the statutory notice requirements for the small landlord exemption.

The George-Anne Daily, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.

Evaluating A Dual-Beacon Hartmann Turbulence Profiling Technique Using Wave Optics Simulations, Benjamin C. Wilson, Matthew Kalensky, Santasri Bose-Pillai, Jack E. Mccrae

Faculty Publications

Resolving how optical turbulence varies along a propagation path remains a key challenge for designers of free-space optical propagation systems. Instruments such as scintillometers and differential image motion monitors are commonly used, but only provide path-integrated turbulence estimates. Point sensors provide localized estimates of turbulence strength and can be used to generate path-resolved profiles when an array of point sensors are distributed along the optical path. However, this approach can be costly and complex to deploy in certain environments. Alternatively, a single point sensor can be mounted on a mobile platform that collects data while traversing the optical path, although …

Research And Innovation Update, July 22, 2026, Office Of The Vice President For Research And Innovation

Office of Research, Economic Engagement and Outreach

No abstract provided.

Trust, Delegation, And Alignment In Human-Ai Decision Making, Erik O. Kimbrough, Brennan Mcdavid, Diba Vazirian

ESI Working Papers

This paper studies delegation to artificial intelligence in a setting where human principals retain the consequences of delegated choices. Participants wrote prompts instructing ChatGPT-4o mini how to choose on their behalf in three canonical economic domains: risky choice, intertemporal choice, and social allocation. We then elicited the compensation participants required to let the AI’s choices count for payment and compared participants’ own choices to choices generated from their prompts. The design produces two central empirical objects: a revealed measure of reluctance to delegate, captured by willingness to accept compensation for AI delegation, and a behavioral measure of alignment, captured by …