Digital Commons Network^™

Antibody Response Of Cattle To Vaccination With Commercial Modified Live Rabies Vaccines In Guatemala, Amy T. Gilbert, Lauren Greenberg, David Moran, Marlon Alvarado, Daniel L. Garcia, Leonard Peruski

United States Department of Agriculture Wildlife Services: Staff Publications

Vampire bat rabies is a public and animal health concern throughout Latin America. As part of an ecological study of vampire bat depredation on cattle in southern Guatemala,we conducted a vaccine seroconversion study among three dairy farms. The main objectives of this cross sectional and cohort study were to understand factors associated withbat bites among cattle, to determine whether unvaccinated cattle had evidence of rabies virus exposure and evaluate whether exposure was related to bat bite prevalence, and to assess whether cattle demonstrate adequate seroconversion to two commercial vaccines used in Guatemala. In 2012, baseline blood samples were collected immediately …

Effects Of Barred Owl (Strix Varia) Range Expansion On Haemoproteus Parasite Assemblage Dynamics And Transmission In Barred And Northern Spotted Owls (Strix Occidentalis Caurina), Krista E. Lewicki, Kathryn P. Huyvaert, Antoinette J. Piaggio, Lowell V. Diller, Alan B. Franklin

United States Department of Agriculture Wildlife Services: Staff Publications

The range of the barred owl (Strix varia) has expanded westward over the past century and now entirely overlaps the range of the federally threatened northern spotted owl (S. occidentalis caurina) in the Pacific Northwest. We compared Haemoproteus blood parasite assemblages among northern spotted owls in their native range and barred owls in both their native and invasive ranges to evaluate predictions of five hypotheses about parasites and biological invasions: (1) Enemy Release, where hosts benefit from a loss of parasites in their invasive range, (2) Enemy of My Enemy, where invasive hosts introduce parasites to …

Subtype-Specific Influenza A Virus Antibodies In Canada Geese (Branta Canadensis), Whitney M. Kistler, David E. Stallknecht, Thomas J. Deliberto, Kyle Van Why, Michael J. Yabsley

United States Department of Agriculture Wildlife Services: Staff Publications

Historically, surveillance for influenza A viruses (IAVs) in wild birds has relied on viral detection assays. This was largely due to poor performance of serological assays in wild birds; however, recently developed commercial serological assays have improved the ability to detect IAV antibodies in wild birds. Serological surveillance for IAV antibodies in Canada geese (Branta canadensis) has shown that, despite a low prevalence of virus isolations, Canada geese are frequently exposed to IAVs and that exposure increases with latitude, which follows virus isolation prevalence patterns observed in dabbling ducks. The objectives of this study were to further evaluate IAV antibodies …

Demographic And Spatiotemporal Patterns Of Avian Influenza Infection At The Continental Scale, And In Relation To Annual Life Cycle Of A Migratory Host, Rodolfo Nallar, Zsuzsanna Papp, Tasha Epp, Frederick A. Leighton, Seth R. Swafford, Thomas J. Deliberto, Robert J. Dusek, Hon S. Ip, Jeffrey Hall, Yohannes Berhane, Samantha E.J. Gibbs, Catherine Soos

United States Department of Agriculture Wildlife Services: Staff Publications

Since the spread of highly pathogenic avian influenza (HPAI) H5N1 in the eastern hemisphere, numerous surveillance programs and studies have been undertaken to detect the occurrence, distribution, or spread of avian influenza viruses (AIV) in wild bird populations worldwide. To identify demographic determinants and spatiotemporal patterns of AIV infection in long distance migratory waterfowl in North America, we fitted generalized linear models with binominal distribution to analyze results from 13,574 blue-winged teal (Anas discors, BWTE) sampled in 2007 to 2010 year round during AIV surveillance programs in Canada and the United States. Our analyses revealed that during late summer staging …

Contact Heterogeneities In Feral Swine: Implications For Disease Management And Future Research, Kim M. Pepin, Amy J. Davis, James C. Beasley, Raoul Boughton, Tyler A. Campbell, Susan M. Cooper, Wesson D. Gaston, Steve Hartley, John C. Kilgo, Samantha M. Wisely, A. Christy Wyckoff, Kurt C. Vercauteren

United States Department of Agriculture Wildlife Services: Staff Publications

Contact rates vary widely among individuals in socially structured wildlife populations. Understanding the interplay of factors responsible for this variation is essential for planning effective disease management. Feral swine (Sus scrofa) are a socially structured species which pose an increasing threat to livestock and human health, and little is known about contact structure. We analyzed 11 GPS data sets from across the United States to understand the interplay of ecological and demographic factors on variation in co-location rates, a proxy for contact rates. Between-sounder contact rates strongly depended on the distance among home ranges (less contact among sounders …

Antibody Response Of Cattle To Vaccination With Commercialmodified Live Rabies Vaccines In Guatemala, Amy T. Gilbert, Lauren Greenberg, David Moran, Danilo Alvarez, Marlon Alvarado, Daniel L. Garcia, Leonard Peruski

United States Department of Agriculture Wildlife Services: Staff Publications

Vampire bat rabies is a public and animal health concern throughout Latin America. Aspart of an ecological study of vampire bat depredation on cattle in southern Guatemala,we conducted a vaccine seroconversion study among three dairy farms. The main objec-tives of this cross sectional and cohort study were to understand factors associated withbat bites among cattle, to determine whether unvaccinated cattle had evidence of rabiesvirus exposure and evaluate whether exposure was related to bat bite prevalence, and toassess whether cattle demonstrate adequate seroconversion to two commercial vaccinesused in Guatemala. In 2012, baseline blood samples were collected immediately prior tointramuscular inoculation of …

Widespread Detection Of Antibodies To Leptospira In Feral Swine In The United States, K. K. Pedersen, K. L. Pabilonia, T. D. Anderson, S. N. Bevins, C. R. Hicks, J. M. Kloft, Thomas J. Deliberto

United States Department of Agriculture Wildlife Services: Staff Publications

As feral swine continue to expand their geographical range and distribution across the United States, their involvement in crop damage, livestock predation, and pathogen transmission is likely to increase. Despite the relatively recent discovery of feral swine involvement in the aetiology of a variety of pathogens, their propensity to transmit and carry a wide variety of pathogens is disconcerting. We examined sera from 2055 feral swine for antibody presence to six serovars of Leptospira that can also infect humans, livestock or domestic animals. About 13% of all samples tested positive for at least one serovar, suggesting that Leptospira infection is …

West Nile Virus Antibody Decay Rate In Free-Ranging Birds, Eileen M. Mckee, Edward D. Walker, Tavis K. Anderson, Uriel D. Kitron, Jeffrey D. Brawn, Bethany L. Krebs, Christina Newman, Marilyn O. Ruiz, Rebecca S. Levine, Mary E. Carrington, Robert G. Mclean, Tony L. Goldberg, Gabriel L. Hamer

United States Department of Agriculture Wildlife Services: Staff Publications

Antibody duration, following a humoral immune response to West Nile virus (WNV) infection, is poorly understood in free-ranging avian hosts. Quantifying antibody decay rate is important for interpreting serologic results and for understanding the potential for birds to serorevert and become susceptible again. We sampled free-ranging birds in Chicago, Illinois, US, from 2005 to 2011 and Atlanta, Georgia, US, from 2010 to 2012 to examine the dynamics of antibody decay following natural WNV infection. Using serial dilutions in a blocking enzymelinked immunosorbent assay, we quantified WNV antibody titer in repeated blood samples from individual birds over time. We quantified a …

Knowledge, Attitudes And Practices Regarding Rabies And Exposure To Bats In Two Rural Communities In Guatemala, David Moran, Patricia Juliao, Danilo Alvarez, Kim A. Lindblade, James A. Ellison, Amy T. Gilbert, Brett Petersen, Charles Rupprecht, Sergio Recuenco

United States Department of Agriculture Wildlife Services: Staff Publications

Background: Rabies is a fatal encephalitis caused by rabies virus, of the genus Lyssavirus. The principal reservoir for rabies in Latin America is the common vampire bat (Desmodus rotundus), which feeds routinely on the blood of cattle, and when livestock are scarce, may prey on other mammals, including humans. Although rabies is endemic in common vampire bat populations in Guatemala, there is limited research on the extent of exposure to bats among human populations living near bat refuges.

Results: A random sample of 270 of 473 households (57%) in two communities located within 2 Km of …

Novel Paramyxoviruses In Bats From Sub-Saharan Africa, 2007–2012, Marinda Mortlock, Ivan V. Kuzmin, Jacqueline Weyer, Amy T. Gilbert, Bernard Agwanda, Charles E. Rupprecht, Louis H. Nel, Teresa Kearney, Jean M. Malekani, Wanda Markotter

United States Department of Agriculture Wildlife Services: Staff Publications

As part of a larger survey for detection of pathogens among wildlife in sub-Saharan Africa conducted during 2007–2012, multiple diverse paramyxovirus sequences were detected in renal tissues of bats. Phylogenetic analysis supports the presence of at least 2 major viral lineages and suggests that paramyxoviruses are strongly associated with several bat genera.

Threats To Humans And Beasts, Kurt C. Vercauteren

United States Department of Agriculture Wildlife Services: Staff Publications

The transmission of pathogens from wildlife to livestock and humans is an increasing concern across the globe. Dr Kurt VerCauteren and colleagues are performing multifaceted research into wildlife diseases and looking for new and practical means of reducing their occurrence and burden.

Exposure To Rabies In Small Indian Mongooses (Herpestes Auropunctatus) From Two Regions In Puerto Rico, Are R. Berentsen, Shylo R. Johnson, Amy T. Gilbert, Kurt C. Vercauteren

United States Department of Agriculture Wildlife Services: Staff Publications

The small Indian mongoose (Herpestes auropunctatus) was introduced to several Caribbean Islands to control rat (Rattus spp.) damage to sugarcane plantations. Mongooses failed at suppressing rat populations and are now considered pests throughout most of their introduced range. Importantly, mongooses are rabies reservoirs on several Caribbean Islands. In Puerto Rico, mongooses have been implicated in up to 70%of reported animal rabies cases. There is no rabies vaccination program for wildlife in Puerto Rico, and data on rabies in mongooses are limited. We conducted a serosurvey of mongooses in two different ecologic environments in Puerto Rico: El Yunque National Forest and …

Rabies Surveillance Among Bats In Tennessee, Usa, 1996–2010, Amy T. Gilbert, Gary F. Mccracken, Lorinda L. Sheeler, Lisa I. Muller, Dorcas O'Rourke, William J. Kelch, John C. New Jr.

United States Department of Agriculture Wildlife Services: Staff Publications

Rabies virus (RABV) infects multiple bat species in the Americas, and enzootic foci perpetuate in bats principally via intraspecific transmission. In recent years, bats have been implicated in over 90% of human rabies cases in the US. In Tennessee, two human cases of rabies have occurred since 1960: one case in 1994 associated with a tricolored bat (Perimyotis subflavus) RABV variant and another in 2002 associated with the tricolored/silver-haired bat (P. subflavus/ Lasionycteris noctivagans) RABV variant. From 1996 to 2010, 2,039 bats were submitted for rabies testing in Tennessee. Among 1,943 bats in satisfactory condition for testing and with a …

Network Analysis Of Host–Virus Communities In Bats And Rodents Reveals Determinants Of Cross-Species Transmission, Angela D. Luis, Thomas J. O'Shea, David T.S. Hayman, James L.N. Wood, Andrew A. Cunningham, Amy T. Gilbert, James N. Mills, Colleen T. Webb

United States Department of Agriculture Wildlife Services: Staff Publications

Bats are natural reservoirs of several important emerging viruses. Cross-species transmission appears to be quite common among bats, which may contribute to their unique reservoir potential. Therefore, understanding the importance of bats as reservoirs requires examining them in a community context rather than concentrating on individual species. Here, we use a network approach to identify ecological and biological correlates of cross-species virus transmission in bats and rodents, another important host group. We show that given our current knowledge the bat viral sharing network is more connected than the rodent network, suggesting viruses may pass more easily between bat species. We …

Modeling And Mapping The Probability Of Occurrence Of Invasive Wild Pigs Across The Contiguous United States, Meredith L. Mcclure, Christopher L. Burdett, Matthew L. Farnsworth, Mark W. Lutman, David M. Theobald, Philip D. Riggs, Daniel A. Grear, Ryan S. Miller

United States Department of Agriculture Wildlife Services: Staff Publications

Wild pigs (Sus scrofa), also known as wild swine, feral pigs, or feral hogs, are one of the most widespread and successful invasive species around the world. Wild pigs have been linked to extensive and costly agricultural damage and present a serious threat to plant and animal communities due to their rooting behavior and omnivorous diet. We modeled the current distribution of wild pigs in the United States to better understand the physiological and ecological factors that may determine their invasive potential and to guide future study and eradication efforts. Using national-scale wild pig occurrence data reported between 1982 and …

Novel Eurasian Highly Pathogenic Avian Influenza A H5 Viruses In Wild Birds, Washington, Usa, 2014, Hon S. Ip, Mia Kim Torchetti, Rocio Crespo, Paul Kohrs, Paul Debruyn, Kristin G. Mansfield, Timothy Baszler, Lyndon Badcoe, Barbara Bodenstein, Valerie Shearn-Bochsler, Mary Lea Killian, Janice C. Pedersen, Nichole Hines, Thomas Gidlewski, Thomas J. Deliberto, Jonathan M. Sleeman

United States Department of Agriculture Wildlife Services: Staff Publications

The novel Eurasian lineage clade 2.3.4.4 highly pathogenic avian influenza (HPAI) A(H5N8) virus (http://www.who.int/influenza/gisrs_laboratory/h5_nomenclature_clade2344/en/) spread rapidly and globally during 2014, substantially affecting poultry populations. The first outbreaks were reported during January 2014 in chickens and domestic ducks in South Korea and subsequently in China and Japan (1–4), reaching Germany, the Netherlands, and the United Kingdom by November 2014 and Italy in early December 2014 (5). Also in November 2014, a novel HPAI H5N2 virus was reported in outbreaks on chicken and turkey farms in Fraser Valley, British Columbia, Canada (5). This H5N2 influenza virus is a reassortant that contains the …

Evaluation Of Rhodamine B As A Biomarker For Assessing Bait Acceptance In Wild Pigs, James Beasley, Sarah C. Webster, Olin E. Rhodes Jr., Fred L. Cunningham

United States Department of Agriculture Wildlife Services: Staff Publications

Worldwide, there is growing interest in the use of pharmaceutical baits to control populations of wild pigs (Sus scrofa). In this study we evaluated the utility of Rhodamine B (RB), a chemical marker commonly used in wildlife research and management, as a potential biomarker for quantifying bait uptake in wild pigs. Thirty wild pigs were live-trapped, transported to a captive facility on the Department of Energy’s Savannah River Site located in South Carolina, USA, during autumn 2013, and administered RB orally at a dosage of 30mg/kg. Eight vibrissae and guard hairs were collected pre- and post-RB exposure (7 …

Serologic Survey Of Snowshoe Hares (Lepus Americanus) In The Greater Yellowstone Area For Brucellosis, Tularemia, And Snowshoe Hare Virus, Jack Rhyan, Dan Tyers, Jeremy Zimmer, Kristen Lewandowski, Steve Hennager, John Young, Ryan Pappert, Amanda Panella, Olga Kosoy

United States Department of Agriculture Wildlife Services: Staff Publications

We examined sera from snowshoe hares (Lepus americanus) livetrapped in the northern Greater Yellowstone Area (GYA), US, for antibodies to Brucella abortus, Francisella tularensis, and snowshoe hare virus (SSHV). Zero of 90, 0 of 67, and 40 of 100 samples were antibody positive for B. abortus, F. tularensis, and SSHV, respectively. Hares were trapped from 2009 to 2012, and of the six animals that were captured twice with at least 1 yr between captures, four developed antibody to SSHV, indicating active exposure to the agent, These findings suggest snowshoe hares in the GYA do not play …

Exposure Of Feral Swine (Sus Scrofa) In The United States To Selected Pathogens, John A. Baroch, Carl A. Gagnon, Sonia Lacouture, Marcelo Gottschalk

United States Department of Agriculture Wildlife Services: Staff Publications

Feral swine (Sus scrofa) are widely distributed in the United States. In 2011 and 2012, serum samples and tonsils were recovered from 162 and 37 feral swine, respectively, in the US to evaluate exposure to important swine endemic pathogens. Antibodies against porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV2) were found in 2.5% and 25.3% of tested sera, respectively. Positive serological reactions against Mycoplasma hyopneumoniae and Actinobacillus pleuropneumoniae have been detected in 19.7% and 69.7% of animals. More than 15% of animals presented antibodies against these 2 pathogens simultaneously. Most animals were also …

Large-Scale Avian Influenza Surveillance In Wild Birds Throughout The United States, Sarah N. Bevins, Kerri Pedersen, Mark W. Lutman, John A. Baroch, Brandon S. Schmit, Dennis Kohler, Thomas Gidlewski, Dale L. Nolte, Seth R. Swafford, Thomas J. Deliberto

United States Department of Agriculture Wildlife Services: Staff Publications

Avian influenza is a viral disease that primarily infects wild and domestic birds, but it also can be transmitted to a variety of mammals. In 2006, the United States of America Departments of Agriculture and Interior designed a large-scale, interagency surveillance effort that sought to determine if highly pathogenic avian influenza viruses were present in wild bird populations within the United States of America. This program, combined with the Canadian and Mexican surveillance programs, represented the largest, coordinated wildlife disease surveillance program ever implemented. Here we analyze data from 197,885 samples that were collected from over 200 wild bird species. …

Influenza A Subtype H3 Viruses In Feral Swine, United States, 2011–2012, Zhixin Feng, John A. Baroch, Li-Ping Long, Yifei Xu, Frederick L. Cunningham, Kerri Pedersen, Mark W. Lutman, Brandon S. Schmidt, Andrew S. Bowman, Thomas J. Deliberto, Xiu-Feng Wan

United States Department of Agriculture Wildlife Services: Staff Publications

To determine whether, and to what extent, influenza A subtype H3 viruses were present in feral swine in the United States, we conducted serologic and virologic surveillance during October 2011–September 2012. These animals were periodically exposed to and infected with A(H3N2) viruses, suggesting they may threaten human and animal health.

Developing Transmissible Vaccines For Animal Infections: Intrinsically Safe Designs And A Staged Transparent Development Process Will Be Essential, Daniel G. Streiker, Megan E. Griffiths, Rustom Antia, Laura Bergner, Peter Bowman, Maria Vitoria Dos Santos De Moraes, Kevin Esvelt, Mike Famulare, Amy T. Gilbert, Biao He, Michael A. Jarvis, David A. Kennedy, Jennifer Kuzma, Carolyne Nasi,Iyu Wanyonyi, Christopher Remien, Tonie Rocke, Kyle Rosenke, Courtney Schreiner, Justin Sheen, David Simons, Ivet A. Yordanova, James J. Bull, Scott L. Nuismer

United States Department of Agriculture Wildlife Services: Staff Publications

Developing Transmissible Vaccines for Animal Infections: Intrinsically Safe Designs and a Staged Transparent Development Process Will Be Essential

Intrinsically safe, biologically compelling vaccine designs

Pahsed development must incorporate checkpoints and engagement

Staged development with established checkpoints

Wquitable partnerships with international governance

Toward deployment

Workshop organization

Seven proposed commitm ents for the responsible development of transmissible vaccines for infectious disease control in animals

Evolutionary outcomes of vaccine transmission depend on the viral vector and the genetic modifications introduced

Identification Of Brucella Suis From Feral Swine In Selected States In The Usa, Kerri Pedersen, Christine R. Quance, Suelee Robbe-Austerman, Antionette J. Piaggio, Sarah N. Bevins, Samuel M. Goldstein, Wesson D. Gaston, Thomas J. Deliberto

United States Department of Agriculture Wildlife Services: Staff Publications

Serologic tests currently available for brucellosis diagnosis detect antibodies to Brucella but do not distinguish between species of Brucella. Although Brucella suis is known to circulate within various feral swine (Sus scrofa) populations, our objective was to determine the primary species of Brucella circulating in feral swine populations in areas of the US with high brucellosis prevalence. We cultured lymph nodes from 183 feral swine. We identified 22 isolates from 21 animals, and all isolates were genotyped as B. suis. Most isolates were B. suis biovar 1, with the exception of two genetically distinct isolates from one feral swine in …

Consequences Associated With The Recent Range Expansion Of Nonnative Feral Swine, Sarah N. Bevins, Kerri Pedersen, Mark W. Lutman, Thomas Gidlewski, Thomas J. Deliberto

United States Department of Agriculture Wildlife Services: Staff Publications

Feral swine (Sus scrofa) have been repeatedly introduced to locations around the world. Aided by both an adaptable biology and deliberate introductions by people, the range of invasive feral swine in the United States has expanded from 17 to 38 states over the past 30 years. The swine’s generalist diet combined with high population densities can complicate efforts to conserve threatened and endangered species, and losses from crop damage and livestock predation in the United States alone are estimated to be more than $1 billion. In addition, feral swine can be a reservoir for multiple pathogens, some of …

Forecasting The Spread Of Raccoon Rabies Using A Purpose-Specific Group Decision-Making Process., Aaron M. Anderson, Stephanie A. Shwiff, Richard B. Chipman, Todd C. Atwood, Tyler Cozzens, Frank Fillo, Robert Hale, Brody Hatch, Joanne Maki, Olin E. Rhodes Jr., Erin E. Rees, Charles E. Rupprecht, Rowland Tinline, Kurt C. Vercauteren, Dennis Slate

United States Department of Agriculture Wildlife Services: Staff Publications

The Centers for Disease Control (CDC) and USDA Wildlife Services (WS) have been involved in an oral rabies vaccination (ORV) program for raccoons (Procyon lotor) that has slowed the westward spread of raccoon rabies. The objective of this study was to forecast the spread of the disease if an ORV zone was not maintained. A group decision-making process was designed to address the forecasting problem and was implemented using a group of 15 experts and 4 support personnel at a meeting at the USDA National Wildlife Research Center. Ten expansion regions were constructed that described the spread of …

The Scent Of Disease: Human Body Odor Contains An Early Chemosensory Cue Of Sickness, Mats J. Olsson, Johan N. Lundstrom, Bruce A. Kimball, Amy R. Gordon, Bianka Karshikoff, Nishteman Hosseini, Kimmo Sorjonen, Caroline Olgart Hoglund, Carmen Solares, Anne Soop, John Axelsson, Mats Lekander

United States Department of Agriculture Wildlife Services: Staff Publications

Observational studies have suggested that with time, some diseases result in a characteristic odor emanating from different sources on the body of a sick individual. Evolutionarily, however, it would be more advantageous if the innate immune response were detectable by healthy individuals as a first line of defense against infection by various pathogens, to optimize avoidance of contagion. We activated the innate immune system in healthy individuals by injecting them with endotoxin (lipopolysaccharide). Within just a few hours, endotoxin-exposed individuals had a more aversive body odor relative to when they were exposed to a placebo. Moreover, this effect was statistically …

Impacts From Control Operations On A Recreationally Hunted Feral Swine Population At A Large Military Installation In Florida, Richard M. Engeman, Troy Hershberger, Steve Orzell, Rodney Felix, Gary Killian, John Woolard, Jon Cornman, David Romano, Chet Huddleston, Pat Zimmerman, Chris Barre, Eric A. Tillman, Michael L. Avery

United States Department of Agriculture Wildlife Services: Staff Publications

Feral swine were targeted for control at Avon Park Air Force Range in south-central Florida to avert damage to sensitive wetland habitats on the 40,000-ha base.We conducted a 5-year study to assess impacts from control to this population that had been recreationally hunted formany years. Control was initiated in early 2009. The feral swine population was monitored from 2008 to 2012 using a passive tracking index (PTI) during the dry and wet seasons and using recreational hunter take rates from the dry season. All three indices showed substantial feral swine declines after implementing control, with indices leveling for the final …

A Pilot Study Exploring The Use Of Breath Analysis To Differentiate Healthy Cattle From Cattle Experimentally Infected With Mycobacterium Bovis, Christine K. Ellis, Randal S. Stahl, Pauline Nol, W. Ray Waters, Mitchell V. Palmer, Jack C. Rhyan, Kurt C. Vercauteren, Matthew Mccollum, M. D. Salman

United States Department of Agriculture Wildlife Services: Staff Publications

Bovine tuberculosis, caused by Mycobacterium bovis, is a zoonotic disease of international public health importance. Antemortem surveillance is essential for control; however, current surveillance tests are hampered by limitations affecting ease of use or quality of results. There is an emerging interest in human and veterinary medicine in diagnosing disease via identification of volatile organic compounds produced by pathogens and host pathogen interactions. The objective of this pilot study was to explore application of existing human breath collection and analysis methodologies to cattle as a means to identify M. bovis infection through detection of unique volatile organic compouds or changes …

Novel Management Methods: Immunocontraception And Other Fertility Control Tools, Giovanna Massei, Dave Cowan, Douglas C. Eckery

United States Department of Agriculture Wildlife Services: Staff Publications

Impacts of overabundant ungulate populations on human activities and conservation include crop and forestry losses, collisions with vehicles, disease transmission, nuisance behaviour, damage to infrastructures, predation on livestock and native species, and reduction of biodiversity in plant and animal communities (e.g. Curtis et ai., 2002; Massei et al., 2011; Reimoser and Putman, 2011; Ferroglio et ai., 2011; Langbein et al., 2011). Current trends in human population growth and landscape development indicate that human-ungulate conflicts in Europe, as well as in the United States, are likely to increase in parallel with increased expansion in numbers and range of many of these …

Improving Pandemic Influenza Risk Assessment, Colin A. Russell, Peter M. Kasson, Ruben O. Donis, Steven Riley, John Dunbar, Andrew Rambaut, Jason Asher, Stephen Burke, C. Todd Davis, Rebecca J. Garten, Sandrasegaram Gnanakaran, Simon I. Hay, Sander Herfst, Nicola S. Lewis, James O. Lloyd-Smith, Catherine A. Macken, Sebastian Maurer-Stroh, Elizabeth Neuhaus, Colin R. Parrish, Kim M. Pepin, Samuel S. Shepard, David L. Smith, David L. Suarez, Susan C. Trock, Marc-Alain Widdowson, Dylan B. George, Marc Lipsitch, Jesse D. Bloom

United States Department of Agriculture Wildlife Services: Staff Publications

Assessing the pandemic risk posed by specific non-human influenza A viruses is an important goal in public health research. As influenza virus genome sequencing becomes cheaper, faster, and more readily available, the ability to predict pandemic potential from sequence data could transform pandemic influenza risk assessment capabilities. However, the complexities of the relationships between virus genotype and phenotype make such predictions extremely difficult. The integration of experimental work, computational tool development, and analysis of evolutionary pathways, together with refinements to influenza surveillance, has the potential to transform our ability to assess the risks posed to humans by non-human influenza viruses …