Digital Commons Network^™

The Virtual Hip: An Anatomically Accurate Finite Element Model Based On The Visible Human Dataset, Jonathan M. Ford

USF Tampa Graduate Theses and Dissertations

The purpose of this study is to determine if element decimation of a 3-D anatomical model affects the results of Finite Element Analysis (FEA). FEA has been increasingly applied to the biological and medical sciences. In order for an anatomical model to successfully run in FEA, the 3-D model’s complex geometry must be simplified, resulting in a loss of anatomical detail. The process of decimation reduces the number of elements within the structure and creates a simpler approximation of the model. Using the National Library of Medicine’s Visible Human Male dataset, a virtual 3-D representation of several structures of the …

The Human In 3d: Advanced Morphometric Analysis Of High-Resolution Anatomically Accurate Computed Models, Summer J. Decker

USF Tampa Graduate Theses and Dissertations

Computed virtual models of anatomical structures are proving to be of increasing value in clinical medicine, education and research. With a variety of fields focused on craniofacial and pelvic anatomy there is a need for accurate anatomical models. Recent technological advancements in computer and medical imaging technologies have provided the tools necessary to develop three-dimensional (3D) functional models of human anatomy for use in medicine (surgical planning and education), forensics and engineering (computer-aided design (CAD) and finite element analysis).

Traditionally caliper methodologies are used in the quantitative analysis of human anatomy. In order for experts in anatomy and morphometrics to …

The Biogeochemistry Of Submerged Coastal Karst Features In West Central Florida, Keith Michael Garman

USF Tampa Graduate Theses and Dissertations

West Central Florida is a complex karst environment with numerous sinkholes, springs, and submerged cave systems. Many of these karst features are anchialine, located within the subterranean estuary where freshwater and saltwater mix. Water quality data and/or fauna data were obtained from twenty-one karst features and their associated cave systems. The anchialine karst environment of the study area has a wide range of habitats with measured salinities ranging from freshwater at <0.2 ppt to sulfidic, hypersaline water at 38.5 ppt and measured pH readings ranging from 6.39 in water impacted by sulfur oxidizing bacteria to 10.3 in an isolated room of a cave. Stygobitic crustaceans were identified in conduits extending beneath the Gulf of Mexico supporting the hypotheses that freshwater crustaceans could survive higher sea levels in freshwater conduits beneath saltwater. The fauna associated with the anchialine cave systems included Sabellidae and Polychaeta worms, hydroids, cnidarians and hydrobiid snails. Jewfish Sink, like other anaerobic marine basins that were submarine springs, has four zones: oxic zone, transition zone, upper anoxic zone and anoxic bottom water. The upper zones have seasonal water quality variations from winter cooling and sinking of surface water and changes in the microbial communities. Activity of sulfate reducing bacteria is carbon limited in the anoxic zones, where sulfate reduction is the major metabolic process, and primary production is phosphate limited in the oxic zones. Organic input from the Gulf of Mexico drives the bacterial anaerobic ecosystem, resulting in a “sulfide pump”, in which sulfide percolates upward removing oxygen from the overlying sediment.

Academic Performance, Persistence, And Degree Completion Of Associate In Arts Degree Recipients Transferring To A Four-Year Multi-Campus Institution, Saul Reyes

USF Tampa Graduate Theses and Dissertations

This study assessed if there were differences in the academic performance, persistence, and degree completion for Associate in Arts transfer students in selected majors who enrolled in the different campuses of a multi-campus university. This causal comparative study analyzed historical student enrollment data from a large, urban, public, research university. Multiple and logistic regression techniques were used to simultaneously control for important independent variables identified in the literature. Variables that were significant (p < .05) for at least one of the three dependent variables included campus, major, community college GPA, gender, and ethnicity. Significant campus differences were found in academic performance, but not for persistence or degree completion. Significant differences by major were reported for academic performance, persistence, and degree completion.

Microbialites From The Freshwater System Of Cuatro Ciénegas, Mexico: Genomic, Molecular Organic, And Stable Isotopic Perspectives, Anthony G. Nitti

USF Tampa Graduate Theses and Dissertations

Modern microbialites are carbonate-precipitating microbial mats and

represent the closest living analogues to ancient stromatolites. These ancient

carbonate formations are the oldest fossil evidence of life on Earth; however, our

comprehension of their relationship to early earth ecosystems relies heavily on

understanding the formation of modern microbialites. Research regarding these

formation processes has suggested that chemical constraints of CaCO

3

precipitation vary on sub-millimeter spatial scales within the living microbial

community. In an attempt to shed light on the importance of these chemical

microenvironments, this study focused on understanding the spatial distribution

of the organisms and processes involved in the …

A Microwave Radiometer For Close Proximity Core Body Temperature Monitoring: Design, Development, And Experimentation, Quenton Bonds

USF Tampa Graduate Theses and Dissertations

Presented is a radiometric sensor and associated electromagnetic propagation models, developed to facilitate non-invasive core body temperature extraction. The system has been designed as a close-proximity sensor to detect thermal emissions radiated from deep-seated tissue 1 cm – 3 cm inside the human body. The sensor is intended for close proximity health monitoring applications, with potential implications for deployment into the improved astronaut liquid cooling garment (LCG). The sensor is developed for high accuracy and resolution. Therefore, certain design issues that distort the close proximity measurement have been identified and resolved. An integrated cavity-backed slot antenna (CBSA) is designed to …

Growth And Characterization Of Epitaxial Thin Films And Multiferroic Heterostructures Of Ferromagnetic And Ferroelectric Materials, Devajyoti Mukherjee

USF Tampa Graduate Theses and Dissertations

Multiferroic materials exhibit unique properties such as simultaneous existence of

two or more of coupled ferroic order parameters (ferromagnetism, ferroelectricity,

ferroelasticity or their anti-ferroic counterparts) in a single material. Recent years have

seen a huge research interest in multiferroic materials for their potential application as

high density non-volatile memory devices. However, the scarcity of these materials in

single phase and the weak coupling of their ferroic components have directed the

research towards multiferroic heterostructures. These systems operate by coupling the

magnetic and electric properties of two materials, generally a ferromagnetic material and

a ferroelectric material via strain. In this work, …

Applications Of Molecular Dynamics Techniques And Spectroscopic Theories To Aqueous Interfaces, Anthony Green

USF Tampa Graduate Theses and Dissertations

The primary goal of spectroscopy is to obtain molecularly detailed information about the system under study. Sum frequency generation (SFG) vibrational spectroscopy is a nonlinear optical technique that is highly interface specific, and is therefore a powerful tool for understanding interfacial structure and dynamics. SFG is a second order, electronically nonresonant, polarization experiment and is consequently dipole forbidden in isotropic media such as a bulk liquid. Interfaces, however, serve to break the symmetry and produce a signal. Theoretical approximations to vibrational spectra of O-H stretching at aqueous interfaces are constructed using time correlation function (TCF) and instantaneous normal mode (INM) …

A Roof Runoff Strategy And Model For Augmenting Public Water Supply, Robert Carnahan

USF Tampa Graduate Theses and Dissertations

Water is the essential resource that is becoming extremely scarce worldwide. The 21st century will further stress all available water resources through the growth and expansion of developing nations. It is not only the quantity of cheap water that is being depleted, but the quality of these waters is being endangered. Florida is an example where rapid development and an exploding population are competing for shrinking groundwater resources. Current water use does not address the use of alternative supplies and reuses in the United States.

The objective of this research was to determine a strategy for augmenting existing water supplies …

Design, Combinatorial Synthesis, And Biological Evaluation Of Novel Α-Helical Mimetics Based On Functionalized Piperazines As Antagonists Of P53/Mdm2 Interactions, Melissa Elizabeth Topper

USF Tampa Graduate Theses and Dissertations

The p53 protein promotes tumor eradication upon activation, making it an attractive target in cancer therapies. A reported 50% of all human cancers display aberrant activation of the MDM2 oncoprotein, which directly promotes tumorgenesis by inactivating the transcriptional activity of wild type p53, and is commonly associated with drug, chemo, and radio therapy resistance. Previously reported crystallographic analysis of the p53/MDM2 complex infers that the p53 protein forms a 2.5 turn amphipathic alpha helix whose hydrophobic face interacts within a deep hydrophobic cleft in the NH2-terminal domain of the globular MDM2. This suggests that the synthesis of small molecular antagonists …

Design And Combinatorial Synthesis Approach Of Non-Peptidic Trimeric Small Molecules Mimicking I, I + 4(3), I + 7 Positions Of Alpha-Helices, Mingzhou Zhou

USF Tampa Graduate Theses and Dissertations

Protein-protein interactions are key to several biological processes that facilitate signal transduction and many other processes. These interactions are involved in pathways that are critical to many human diseases. Targeting specific protein-protein interactions is a challenging goal because protein-protein interactions are predominately through hydrophobic interactions. Antagonists of the protein-protein interactions need to be perfectly fit into the binding pockets to ensure the activity. The -helical domain of the proteins behaves as the recognition motifs for numerous protein-protein, and protein-nucleic acid interactions. Research has shown that pathways of many diseases contain protein-protein interactions involving -helical domains, e.g. neurological disorders, bacterial infections, …

Core Promoter Function In Brugia Malayi, Michelle Bailey

USF Tampa Graduate Theses and Dissertations

Previous studies have indicated that the promoters of the human filarial parasite Brugia malayi are unusual in that they do not exhibit the CAAT or TATAA sequences usually found in the core domains of promoters of most eukaryotic organisms. Analysis of the promoters of the ribosomal proteins showed that the region flanking the splice leader (SL) addition site plays an important role in transcription and may function as the core promoter domain in B. malayi. To test the hypothesis that the SL addition domain is the most important essential region of the ribosomal protein promoters, the SL addition site of …

Discrimination Of Human And Non-Human Sources Of Pollution In Gulf Of Mexico Waters By Microbial Source Tracking Methods And The Investigation Of The Influence Of Environmental Factors On Escherichia Coli Survival, Asja Korajkic

USF Tampa Graduate Theses and Dissertations

Water quality worldwide is assessed by enumeration of fecal indicator bacteria (FIB) (fecal coliforms, Escherichia coli, and enterococci) intended to act as surrogates for human enteric pathogens. In environmental waters, this predictive relationship is confounded by many possible sources of FIB with varying implications for human health. Many physico-chemical and biological factors influence the fate of enteric pathogens and FIB in aquatic habitats, but are poorly understood, thus limiting our understanding of the usefulness of FIB as fecal pollution indicators.

These studies explored the field application of a “toolbox” approach to microbial source tracking (MST) intended to discriminate between human …

Evolution Of The Hammerhead Cephalofoil: Shape Change, Space Utilization, And Feeding Biomechanics In Hammerhead Sharks (Sphyrnidae), Kyle Reid Mara

USF Tampa Graduate Theses and Dissertations

The relationship between form and function is often used to elucidate the biological role of a structure. Hammerhead sharks offer a unique opportunity to study form and function through phylogeny. Because sphyrnid sharks display a range of cranial morphologies this group can be used to address questions about the evolution of cranial design and investigate the effects of changes in head morphology on feeding structures and bite force. Geometric morphometrics, volumetric analyses, morphological dissections, and phylogenetic analyses of the cephalofoil were used to gain insight into changes in cranial design through evolutionary history. External morphometrics and internal volumetric analyses indicated …

The Gulf Of Mexico Red Snapper Individual Fishing Quota Program: The Effects On The Fishing Industry And Potential Outlook, Nathan Miller

USF Tampa Graduate Theses and Dissertations

In January 2007, the Gulf of Mexico red snapper fishery took a step toward sustainability and began management under an individual fishing quota (IFQ) system. The hope is that direct ownership stakes by fishers brings more direct involvement on behalf of the boat owners and fishermen as well as more responsible and sustainable fishing practices on depressed fish populations. The research was conducted in order to study the welfare of local fishing communities as well as the effects on the red snapper fishery itself. Traditional fisheries and economic data were analyzed. In addition a Data Envelopment Analysis (DEA) of the …

Interface Modifications With Atomic Monolayer, Jayeeta Lahiri

USF Tampa Graduate Theses and Dissertations

No abstract provided.

The Impact Of Maladaptive Schema On Disordered Eating: A Collective Case Study, Susan Hurley

USF Tampa Graduate Theses and Dissertations

This qualitative study is based on the reality that disordered eating such as anorexia nervosa, bulimia nervosa, and compulsive overeating resulting in obesity represent a major and growing problem in community health. Treatment models using cognitive behavioral therapy suggest that those diagnosed with an eating disorder tend to judge themselves in terms of their body shape, weight, and eating habits. However, the recovery rate for those treated for an eating disorder that only addresses those three issues identified above is less than 60%. A number of quantitative studies have provided evidence that other maladaptive schema may contribute to bulimic and …

Effects Of A Shallow-Water Hydrothermal Vent Gradient On Benthic Calcifiers, Tutum Bay, Ambitle Island, Papua New Guinea, Brienne E. Engel

USF Tampa Graduate Theses and Dissertations

Ocean acidification is occurring in response to rapidly increasing concentrations of atmospheric CO2. Shallow-water hydrothermal vent systems have been proposed as natural laboratories for studying the effects of elevated pCO2 on benthic communities. Hydrothermal vents occur at depths of approximately 10m in Tutum Bay, Ambitle Island, Papua New Guinea; these vents are surrounded by a typical-appearing fringing coral-reef community. Groups of live specimens of seven species of reef-dwelling, larger benthic foraminifers, along with segments of calcareous green algae broken from live thalli, were collected from a reef location, placed in small mesh bags, and deployed for five days at six …

Enhancing Gene Expression Signatures In Cancer Prediction Models: Understanding And Managing Classification Complexity, Vidya P. Kamath

USF Tampa Graduate Theses and Dissertations

Cancer can develop through a series of genetic events in combination with external influential factors that alter the progression of the disease. Gene expression studies are designed to provide an enhanced understanding of the progression of cancer and to develop clinically relevant biomarkers of disease, prognosis and response to treatment. One of the main aims of microarray gene expression analyses is to develop signatures that are highly predictive of specific biological states, such as the molecular stage of cancer. This dissertation analyzes the classification complexity inherent in gene expression studies, proposing both techniques for measuring complexity and algorithms for reducing …

The Role Of Microrna-155 In Human Breast Cancer, William Kong

USF Tampa Graduate Theses and Dissertations

Recent statistics reveal breast cancer as the most common cancer among women and accounts for approximately 41,000 mortalities per year. In diagnosis, features such as stage, grade, lymph node metastasis are important prognostic indicators that help guide physicians and oncologist towards optimal patient care. Presence of established pathological markers such as ER, PR, and Her2/neu status would indicate ideal adjuvant therapy situation. Although treatment of these types of breast cancer is well established, cancer that lack all three receptors, “triple negatives” or “basal like” do not respond to adjuvant therapy and are considered more aggressive in that patients tend to …

Re-Connecting: Revitalizing Downtown Clearwater With Environmental Sensibility, Diego Duran

USF Tampa Graduate Theses and Dissertations

Many downtowns in North America have been severed from the rest of the city and from the contextual relationship to their surroundings. Sundered from their context, the ecological characteristics of a site are frequently taken for granted, and the disengagement of its public spaces erodes the downtown's character as well as the urban fabric.

Downtown Clearwater has lost the vitality and vibrancy that once characterized it as a lively district. Because of recent developments in the downtown area, public spaces have been lost between parking lots, high rises and a small number of sporadic residential pockets. Some of the most …

Photothermal Studies Of Carboxymyoglobin, Meagan Small

USF Tampa Graduate Theses and Dissertations

Small ligand diffusion in heme proteins is not fully understood. To help better understand CO diffusion, three systems were investigated: L29H/F43H site-directed sperm whale myoglobin, horse heart myoglobin in a heavy water buffer, and calix[4]resorcinarene. Binding of copper to calix[4]resorcinarene was photophysically characterized to unravel transient binding of small molecules in heme-copper proteins. Copper binding was found to have a low dissociation constant of approximately 8.6 micrometers.. Reaction profiles using photoacoustic calorimetry were constructed for the myoglobin systems. In deuterium oxide, ligand escape is not rate limited by water entry. Large enthalpy differences arise from the thermodynamic properties of deuterium …

Computer Simulation Of Metal-Organic Materials, Abraham C. Stern

USF Tampa Graduate Theses and Dissertations

Computer simulations of metal-organic frameworks are conducted to both

investigate the mechanism of hydrogen sorption and to elucidate a detailed,

molecular-level understanding of the physical interactions that can lead to successful

material design strategies. To this end, important intermolecular interactions are

identified and individually parameterized to yield a highly accurate representation

of the potential energy landscape. Polarization, one such interaction found to play a

significant role in H

2 sorption, is included explicitly for the first time in simulations

of metal-organic frameworks. Permanent electrostatics are usually accounted for by

means of an approximate fit to model compounds. The application of …

Geographic Variation In Life History Tactics, Adaptive Growth Rates, And Habitatspecific Adaptations In Phylogenetically Similar Species: The Eastern Fence Lizard, Sceloporus Undulatus Undulatus, And The Florida Scrub Lizard, Sceloporus Woodi, Travis R. Robbins

USF Tampa Graduate Theses and Dissertations

To understand the evolutionary and ecological significance of geographic variation in life

history traits, we must understand whether the patterns are induced through plastic or adaptive

responses. The Eastern Fence Lizard,

Sceloporus undulatus

, exhibits countergradient variation

(larger body sizes, et cetera, in northern, cooler environments; presumed adaptive) in life history

traits across its large geographic range. However, cogradient variation (the expected result from

a plastic response, although not necessarily inconsistent with adaptation) has been suggested as

a null hypothesis, especially on fine geographic scales because of relatively small environmental

changes. Here we focus on life history variation on a …

Assessing The Ability Of Soils And Sediment To Adsorb And Retain Cs-137 In Puerto Rico, Warner Ithier-Guzman

USF Tampa Graduate Theses and Dissertations

As part of the radioactive exercises taking place around the world anthropogenic radionuclides were introduce to Puerto Rico’s terrestrial and aquatic environments beginning in 1962. Two major projects took place in the island, the Rain Forest Project and the construction of a Boiling Superheat Nuclear Power Plant (BONUS). While in operation several accidental shutdowns occurred at the BONUS facility. One of these accidental shutdowns released 582 MBq into the nearby environment. Vieques an island located few miles east of the main island has received anthropogenic inputs of heavy metals resulting from military practices conducted by the US Navy. Due to …

Characterization Of Unidentified Viruses From Florida, Jessie L. Dyer

USF Tampa Graduate Theses and Dissertations

Public Health and clinical laboratories occasionally obtain viral isolates that cannot be typed by routine methods. Therefore, the sequence-independent, single primer amplification (SISPA) technique was adapted to rapidly identify and characterize viral isolates of unknown etiology. A panel of known (West Nile virus and St. Louis encephalitis virus) and unknown viral isolates (environmental samples collected in Florida) were used to develop and refine the SISPA technique. Selectivity for viral genomic sequences was obtained through enriching viral particles by centrifugation, removal of cellular debris by filtration and removal of host genomic material by benzonase application. The SISPA method successfully amplified the …

Visionary Of Control: The Efficiency, Expertise, And Exclusion Of Alexander James Inglis, Heidi Tilney Kramer

USF Tampa Graduate Theses and Dissertations

Alexander James Inglis was the key contributor to changes enacted in education during the Progressive era. He instituted an administrative and curricular hierarchy in order to create social organization during a chaotic time in American history, thus advancing professionalism in teaching and systematizing a future workforce - teaching previously had no standards, and throngs of immigrants overwhelmed the school system. While necessary at the time, this system of centralization, homogenization, and sorting continues to result in exclusion in secondary education and middle schools. Categorization is Inglis' hallmark in his work in education, following Frederick W. Taylor's managerial practices, and he …

Identifying And Addressing Health Disparities In Black Older Adults With Osteoarthritis, Chivon A. Mingo

USF Tampa Graduate Theses and Dissertations

Osteoarthritis (OA), the most common form of arthritis in older adults, often results in pain, disability and poor psychological well-being. Compared to White adults, Black adults consistently report more pain, more activity limitations, and have different perceptions about OA. Racial disparities also exist in treatments, and prevalence of arthritis. It is imperative to have effective interventions and treatment options for older Blacks. Yet, few arthritis interventions have included Black participants in their samples, and nearly all of those have failed to report separate analyses indicating the effectiveness for Black adults, thus leaving a gap in the literature. The purpose of …

Upper Elementary Boys’ Participation During Group Singing Activities In Single-Sex And Coeducational Classes, Zadda M. Bazzy

USF Tampa Graduate Theses and Dissertations

As boys in the upper elementary grades become increasingly influenced by peer pressure, many are less likely to participate in singing activities because singing is considered a "feminine" activity. The purpose of this research was to explore if there was an effect on upper elementary boys' level of participation during group singing activities when they attended music classes in a single-sex setting.

This study employed a true experimental design and a mixed method. Boys (N = 186) were videotaped during their regular coeducational music classes on two occasions to establish baseline data. Then the students were randomly assigned to …

Victimization Among Individuals With Low Self-Control: Effects On Fear Versus Perceived Risk Of Crime, Casey Williams

USF Tampa Graduate Theses and Dissertations

Fear of crime is an issue that has long been a part of mainstream society through politics and media. However, research on the specific mechanisms of fear and the effects on behavior is sparse. After considering the victim-offender overlap consistently found within the literature, the present study was based on the theory posed within Schreck, Stewart, and Fisher (2006) in which those who are low in self-control may have altered perceptions of fear or risk of crime that might increase the likelihood that the individual will be in risky locations conducive to victimization. The current study also included a novel …