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Behavior Change For Children Participating In Parent-Child Interaction Therapy: A Growth Curve Analysis, Kayla Larosa

USF Tampa Graduate Theses and Dissertations

Disruptive behavior disorders including Attention-Deficit/Hyperactivity Disorder (ADHD), Conduct Disorder (CD), and Oppositional Defiant Disorder (ODD), are listed among the most common reasons youth are referred for mental health services (Centers for Disease Control & Prevention [CDC], 2016b; Kazdin, Mazurick, Siegel, & 1994). Parent-Child Interaction Therapy (PCIT) is one intervention that has been found to reduce clinically significant levels of disruptive behavior. The purpose of the current study was to determine the form of change, typical change trajectory, and individual variation in change for disruptive behavior across the two phases of PCIT; the Child-Directed Interaction (CDI) and Parent-Directed Interaction (PDI) phases. …

Survey Research In Postsecondary Chemistry Education: Measurements Of Faculty Members’ Instructional Practice And Students’ Affect, Rebecca E. Gibbons

USF Tampa Graduate Theses and Dissertations

Collection of data through survey-type measurements and analysis contributes rich, meaningful information to the chemical education research enterprise. This dissertation reports two strands of research that each contribute a “snapshot” of the state of chemical education on two different levels. The first uses survey research methods, collecting data from faculty members to learn about postsecondary chemistry education across the United States. The second uses survey instruments of student achievement emotions within the organic chemistry classroom, collecting longitudinal data to learn about the relationships of emotions with achievement over time. Both areas are of interest because chemical education research produces evidence-based …

Synthesis, Oxidation, And Distribution Of Polyphenols In Strawberry Fruit During Cold Storage, Katrina E. Kelly

USF Tampa Graduate Theses and Dissertations

Plants inherently produce polyphenols (i.e., antioxidants) as a response to reduce oxidative stress caused by abusive environmental pre- and postharvest conditions. These antioxidants, as well as vitamin C, are present in considerable levels in strawberries; however, excessive oxidative stress brought on by improper postharvest handling conditions can reduce the levels of antioxidants in the fruit and shorten the shelf-life of strawberries. Nevertheless, it may be possible to utilize strawberry’s naturally occurring polyphenols to reduce postharvest stress and extend their shelf life. The polyphenolic profile has been previously investigated in several strawberry cultivars, however no studies have determined the unique polyphenolic …

A Machine Learning Framework To Classify Mosquito Species From Smart-Phone Images, Mona Minakshi

USF Tampa Graduate Theses and Dissertations

Mosquito borne diseases have been a constant scourge across the globe resulting in numerous diseases with debilitating consequences, and also death. To derive trends on population of mosquitoes in an area, trained personnel lay traps, and after collecting trapped specimens, they spend hours under a microscope to inspect each specimen for identifying the actual species and logging it. This is vital, because multiple species of mosquitoes can reside in any area, and the vectors that some of them carry are not the same ones carried by others. The species identification process is naturally laborious, and imposes severe cognitive burden, since …

Evaluating Beach Water Quality And Dengue Fever Risk Factors By Satellite Remote Sensing And Artificial Neural Networks, Abdiel Elias Laureano-Rosario

USF Tampa Graduate Theses and Dissertations

Climatic variations, together with large-scale environmental forces and human development affect the quality of coastal recreational waters, creating potential risks to human health. These environmental forces, including increased temperature and precipitation, often promote specific vector-borne diseases in the Caribbean and Gulf of Mexico. Human activities affect water quality through discharges from urban areas, including nutrient and other pollutants derived from wastewater systems. Both water quality of recreational beaches and vector-borne diseases can be better managed by understanding their relationship with local environmental forces.

I evaluated how changes in vector-borne diseases and poor recreational water quality were related to specific environmental …

Dynamic Modeling Of An Advanced Wastewater Treatment Plant, Komal Rathore

USF Tampa Graduate Theses and Dissertations

Advanced wastewater treatment plants have complex biological kinetics, time variant influent rates and long processing times. The modeling and operation control of wastewater treatment plant gets complicated due to these characteristics. However, a robust operational system for a wastewater treatment plant is necessary to increase the efficiency of the plant, reduce energy cost and achieve environmental discharge limits. These discharge limits are set by the National Pollutant Discharge Elimination System (NPDES) for municipal and industrial wastewater treatment plants to limit the amount of nutrients being discharged into the aquatic systems.

This document summarizes the research to develop a supervisory operational …

Understanding Agricultural-Land Conservation From The Perspective Of Landowners In Franklin County, Massachusetts, Rocio Lalanda

USF Tampa Graduate Theses and Dissertations

What motivates agricultural-land owners to use conservation easements? As these legal tools have become a popular strategy for private land conservation in the U.S., a growing body of literature is examining how and why landowners conserve their properties through conservation easements. This research project expands upon environmental, geographical and rural land development literature through a qualitative fieldwork study of 34 private, conservation landowners associated with the Franklin Land Trust, a nonprofit conservation organization in western Massachusetts. The study identifies a broad range of environmental, social, spiritual and financial motivations for agricultural-land owners to conserve their properties, and indicates that for …

A Systems Chemical Biology Approach For Dissecting Differential Molecular Mechanisms Of Action Of Clinical Kinase Inhibitors In Lung Cancer, Natalia Junqueira Sumi

USF Tampa Graduate Theses and Dissertations

Lung cancer is the second most common cancer type and is associated with high mortality rates. The survival rate for lung cancer patients has increased slowly in the last decade mainly as the result of the development of novel targeted and immune therapies. However, non-small cell lung cancer patients lacking known or actionable driver mutations and small cell lung cancer patients with recurrent disease are still in urgent need of new therapies. Drug repurposing is an efficient way to identify new therapies since it uses clinically relevant small molecule drugs. Determination of off-targets of small molecules is a novel approach …

Design, Construction, And Characterization Of The University Of South Florida Wind Tunnel, Jason S. Garcia

USF Tampa Graduate Theses and Dissertations

Much of the aerosol research completed at the University of South Florida has revolved around evaluating industrial hygiene equipment and instrumentation in environmental chambers. Data collected during these studies has provided valuable baseline data on equipment and instrument performance under calm air conditions. A newly constructed wind tunnel now allows researchers to evaluate industrial hygiene instruments under moving air conditions. Because the wind tunnel is capable of producing wind velocities that a worker could encounter in the occupational setting, researchers may gain insight into instrument performance under simulated field conditions. Because aerosols can be introduced into the new wind tunnel …

Microbial Associations Of Four Species Of Algal Symbiont-Bearing Foraminifera From The Florida Reef Tract, Usa, Makenna May Martin

USF Tampa Graduate Theses and Dissertations

Marine microbiome research is a rapidly expanding field of study, as scientists investigate the functions of microbial associations in eukaryotic organisms. Foraminifera are among the most abundant shelled organisms in the oceans, yet little is known of their associated microbiomes. This study investigated microbes associated with four species of Foraminifera that host three kinds of algal endosymbionts. The Order Miliolida, Family Soritidae, was represented by three species: Archaias angulatus and Cyclorbiculina compressa, which both host chlorophyte symbionts, and Sorites orbiculus, which hosts dinoflagellate symbionts. The fourth species, Amphistegina gibbosa, belongs to the Order Rotaliida and hosts diatom endosymbionts. Bacterial DNA …

A Hybrid Dynamic Modeling Of Time-To-Event Processes And Applications, Emmanuel A. Appiah

USF Tampa Graduate Theses and Dissertations

In the survival and reliability data analysis, parametric and nonparametric methods are used to estimate the hazard/risk rate and survival functions. A parametric approach is based on the assumption that the underlying survival distribution belongs to some specific family of closed form distributions (normal, Weibull, exponential, etc.). On the other hand, a nonparametric approach is centered around the best-fitting member of a class of survival distribution functions. Moreover, the Kaplan-Meier and Nelson-Aalen type nonparametric approach do not assume either distribution class or closed-form distributions. Historically, well-known time-to-event processes are death of living specie in populations and failure of component in …

Off-Target Based Drug Repurposing Using Systems Pharmacology, Brent M. Kuenzi

USF Tampa Graduate Theses and Dissertations

The goal of this study was to identify novel drug repurposing opportunities in cancer by utilizing the off-target profiles of clinically relevant kinase inhibitors. This was based on the observation that the global target profiles of compounds are largely ignored and that many compounds have activity that cannot be explained by their cognate target alone. Additionally, by utilizing clinically relevant compounds, any results would hold a high potential for eventual clinical implementation. We utilized a systems pharmacology approach utilizing cell viability-based drug screening to identify compounds with beneficial off-target activity and then using chemical and phosphoproteomics in order to elucidate …

Perceptions Of Quality Of Life, Peer Relationships, And Health Literacy In Adolescents With Phenylketonuria (Pku), Katherine L. Wesley

USF Tampa Graduate Theses and Dissertations

Phenylketonuria (PKU) is a rare inborn error of metabolism that can be managed through lifelong treatment adherence to a restricted diet and supplemental medical formula (Vockley et al., 2014). Untreated PKU can result in severe intellectual disability, anxiety, depression, executive functioning deficits, and seizures (Cappelletti et al., 2013; Moyle et al., 2007). Even individuals who are continuously treated for PKU can experience high rates of anxiety and depression, executive functioning deficits, social difficulties, and lower full-scale IQ scores than their siblings and parents (Bosch et al., 2015; Manti et al., 2016; Waisbren et al., 2007). Additionally, adolescents are at risk …

An Evaluation Of Pit Latrines And User Perception Of Excrement In Ngäbe Communities In Panama, James A. Libby

USF Tampa Graduate Theses and Dissertations

At the end of the Millennium Development Goal (MDG) period in 2015, 2.3 billion people, 31% of the global population, still did not have access to even basic sanitation services. Of these people, 892 million still practice open defecation, and 856 million people use unimproved facilities such as pit latrines without a slab or platform or hanging latrines or bucket latrines (JMP 2017). Sustainable Development Goal (SDG) Target 6.2 now aims to achieve adequate and equitable sanitation and hygiene for all and sets the ambitious target of eradicating open defecation by 2030. While the number of people open defecating was …

The Effects Of Gopher Tortoise (Gopherus Polyphemus) Herbivory On Plant Community Composition And Seed Germination, And The Effects Of Gut Passage On The Germinability Of Seeds: A Meta-Analysis, Jason C. Richardson

USF Tampa Graduate Theses and Dissertations

Herbivory produces direct and indirect effects on plants and at different spatial scales will have varied consequences. Consumption of plants by vertebrate grazers may affect the plants on an organismal level through direct mortality, on a community level by changing species composition or by altering the rate of succession, and even at a whole ecosystem level by altering nutrient cycles.

The majority of the scientific literature has focused extensively on herbivory by mammals and birds. With regard to mammals, studies have shown how folivory affects individual plants, plant populations, and communities of plants.

Mammals, as well as birds, also ingest …

Do All “Good Mothers” Breastfeed? How African American Mothers’ Values And Experiences Of Early Motherhood Influence Their Infant Feeding Choices, Airia S. Papadopoulos

USF Tampa Graduate Theses and Dissertations

The food an infant is fed can reflect many things: a source of nutrition, the social and cultural circumstances into which an infant is born, or even a family’s beliefs about the body and breast milk as a source of nutrition. Exclusive breastfeeding, currently the gold standard for infant feeding in the United States (US), is often identified as an expectation in discourses on being a “good mother.” African American mothers in particular are the least likely group in the US to breastfeed in any capacity and many efforts are underway to increase the breastfeeding rates of this population.

This …

Non-Equilibrium Phase Transitions In Interacting Diffusions, Wael Al-Sawai

USF Tampa Graduate Theses and Dissertations

The theory of thermodynamic phase transitions has played a central role both in theoretical physics and in dynamical systems for several decades. One of its fundamental results is the classification of various physical models into equivalence classes with respect to the scaling behavior of solutions near the critical manifold. From that point of view, systems characterized by the same set of critical exponents are equivalent, regardless of how different the original physical models might be. For non-equilibrium phase transitions, the current theoretical framework is much less developed. In particular, an equivalent classification criterion is not available, thus requiring a specific …

Occupational Noise Exposure Evaluation Of Airline Ramp Workers, Adekunle Ogunyemi

USF Tampa Graduate Theses and Dissertations

Noise exposure is a common hazard to workforce in general although at varying degrees depending on the occupation, as many workers are exposed for long periods of time to potentially hazardous noise.

Every year, twenty-two million workers are exposed to potentially damaging noise at work. In 2015 U.S. businesses paid over $1.5 million in penalties for not protecting workers from noise. (OSHA, 2016). There may be a direct or indirect consequence of the possibilities of overexposure to noise notwithstanding the compulsory hearing protection requests for the occupations with potential hazards, and these exposures usually arise from the various types of …

Exploring Spanish Heritage Language Learning And Task Design For Virtual Worlds, Brandon J. King

USF Tampa Graduate Theses and Dissertations

In this exploratory case study, I take a constant comparative methods type approach to exploring a shift in second language acquisition (SLA) away from approaches built on the assumption that language participants in the U.S. are monolingual English speakers (Block, 2003; Ortega, 2009, 2013; Thompson, 2013; Valdés, 2005), with little initial investment in the language or its culture (Rivera-Mills, 2012; Valdés, Fishman, Chavéz, & Pérez, 2006). This bias has entrenched a monolingual speaker baseline for statistical analysis within many experimental designs (Block, 2003; Ortega, 2009, 2013; Thompson, 2013; Valdés, 2005). Further, I redress this methodological bias by applying sociocultural theoretical …

Studies Aimed At The Synthesis Of Anti-Infective Agents, Ankush Kanwar

USF Tampa Graduate Theses and Dissertations

Infectious diseases continue to be a major concern worldwide. They are the second leading cause of death after heart disease. Factors such as an increasing global population, travel, urbanization, global climate change and evolution of pathogens have made infectious diseases more common. Infectious diseases, particularly neglected tropical diseases (NTDs) result in many deaths worldwide. Malaria and leishmaniasis are two common (NTDs) which affect low income countries around the globe. Low cost drugs with novel mechanism of action are required to tackle the growing resistances of parasites against current drugs used in the developing world, where most of the cases occur. …

Identification Of Novel Hits Against, Ala A. Azhari

USF Tampa Graduate Theses and Dissertations

Leishmaniasis is a disease caused by obligate intracellular parasites of the genus Leishmania, including 20 species that are pathogenic to humans. Female sand fly is the known vector that can transmit the disease. Visceral leishmaniasis is the severe form of the disease that affects internal organs and can be fatal with inappropriate diagnosis or treatment. Leishmania donovani is the causative agent of visceral leishmaniasis. Approximately 350 million in 89 countries are at risk of infection. Around 2 million new cases are reported annually with 500,000 of these are visceral leishmaniasis. Current drug therapies are inadequate due to their toxicity, high …

Spatial Dynamics And Productivity Of A Gulf Of Mexico Commercial Reef Fish Fishery Following Large Scale Disturbance And Management Change, Marcy Lynn Cockrell

USF Tampa Graduate Theses and Dissertations

The Gulf of Mexico commercial reef fish fishery has experienced significant management changes and disturbance in recent years, including transitioning two major fisheries from a traditional open access system into a limited entry individual fishing quota (IFQ) system in 2007 and 2010. Also in 2010, the Deepwater Horizon oil spill (DWH) released an estimated 4.9 million barrels of oil into the Gulf (~206 million U.S. gallons), and is still the largest U.S. environmental disaster to date. Emergency fishing closures initiated shortly after the oil spill began were successful in keeping tainted seafood from reaching markets. However, effects of DWH closures …

The Association Of Size Variation In The Dental Arch To Third Molar Agenesis For A Modern Population, Devin N. Williams

USF Tampa Graduate Theses and Dissertations

The frequency with which individuals do not develop their third molars, or wisdom teeth, is increasing worldwide. This current topic of human evolution is relevant to the research of anthropologists, geneticists, dentists, and other researchers involved in the study of human dentition. Many explanations have been offered to account for the prevalence of molar agenesis including, evolutionary, environmental, and genetic theories. The purpose of this research project is to determine the frequency of third molar agenesis and investigate the relationship between third molar agenesis and maxillomandibular jaw dimensions in a sample of orthodontic patients. This research tests the hypotheses that: …

Tgf-Β2 In Human Milk Research: Exploration Of A New Field Methodology And New Findings Of Biosimilar Tgf-Β2 In Non-Human Milk, Chlöe A. Sweetman

USF Tampa Graduate Theses and Dissertations

Objectives: There are three aims for this thesis: the first is to develop a field and laboratory protocol for the storage and analysis of transforming growth factor–beta 2 (TGF-β2) in human breastmilk; second, to validate this protocol and the immunoassay used to assess this new method; and lastly, to explore the ramifications of biosimilar TGF-β2 across multiple milks on human health, growth, and immunity through the review of laboratory findings and previous literature.

Rational: Little anthropological research has been done on TGF-β2 in human milk. Anthropology as a discipline is well positioned to provide insight into TGF-β2, combining biocultural, evolutionary, …

Extending Spectrophotometric Pht Measurements In Coastal And Estuarine Environments, Nora Katherine Douglas

USF Tampa Graduate Theses and Dissertations

Nearshore and estuarine environments play a vital role in the cycling of carbon, but the effects of ocean acidification in estuarine waters have not been studied as extensively as in the open ocean. One reason for this is the limitation of pH measurement capabilities in low-salinity waters. Typically, pH in these environments has been measured using potentiometric methods that are subject to uncertainties on the order of 0.01. Spectrophotometric methods for measuring pHT offer precision and accuracy superior to those of potentiometric methods. However, previous characterizations for purified sulfonephthalein indicators, used for marine spectrophotometric measurements, are not applicable to estuarine …

Conformational Fluctuations Of Biomolecules Studied Using Molecular Dynamics And Enhanced Sampling, Geoffrey M. Gray

USF Tampa Graduate Theses and Dissertations

Biomolecule structural fluctuations determine function, regulating numerous biological processes My research has shed light on several interesting cases in which structural fluctuations have been identified to assess functional differences. Chapter 2 discusses the effects of structural rearrangement of the β2-β3 loop on the DNA binding affinity of the type 6 human papillomavirus E2 protein. Chapter 3 investigates the effects of phosphorylation on the C-terminal domain of Cdc37, a protein important in the Hsp90 chaperone cycle. Chapter 4 studies the effects on cyclycization on the conformational fluctuations of a γ-AApeptide used for high-throughput libraries. Chapter 5 is a structural study on …

From Florida To Antarctica: Dereplication Strategies And Chemical Investigations Of Marine Organisms, Matthew A. Knestrick

USF Tampa Graduate Theses and Dissertations

In the fight against disease and illness, nature has provided mankind some of our best therapeutics in the form of secondary metabolites. The plant, fungi and animal phyla inhabiting the Earth produce diverse and unique chemistry that can be used in our fight against disease. In the growing threat of drug resistance and pathogen evolution, the field of natural products chemistry strives to explore new biological and chemical diversity sources, and develop innovative methodology to identify and isolate new chemistry faster than ever.

The dissertation herein presented is one such effort to find new, bioactive chemistry from the marine environments. …

“Neither East Nor West”: Shia Women Negotiating Gender Norms In America, Raheleh Dayerizadeh

USF Tampa Graduate Theses and Dissertations

With growing hostilities towards the Ummah (Muslim global community and Diaspora) in Western countries and the fear of Sharia laws, the socialization of international human rights norms within religious institutions, makes for a timely case study. Specifically, this dissertation project aims to capture the process of norm transformation at the grassroots level by investigating the religious, cultural, and social encounter between Islam and the West by interviewing Shia women at a local mosque in Florida. Critical constructivism, post-colonial feminism, and qualitative interpretive methods, are used to address the following: how practicing Shia women are navigating between competing liberal gender equality …

Characterization Of Scanning Mobility Particle Sizers For Use With Nanoaerosols, Michael R. Henderson

USF Tampa Graduate Theses and Dissertations

The purpose of this study was to evaluate the performance of scanning mobility particle sizers in the characterization of nanoaerosols. A sampling chamber was constructed from aluminum and tempered glass, had a volume of 4.6 cubic feet, and was designed for the introduction of aerosols and dilution air, maintenance of aerosol concentration, and continuous exhaust of chamber air. Penetration and aerosol distribution tests were conducted within the chamber. An aerosol generation and measurement system comprised of nitrogen gas, BGI 3 jet Collison Nebulizer, diffusion dryer, aerosol charge neutralizer, mixing chamber, critical orifice, hygrometer, condensation particle counter, scanning mobility particle sizer, …

Investigation Of Alcohol-Induced Changes In Hepatic Histone Modifications Using Mass Spectrometry Based Proteomics, Crystina Leah Kriss

USF Tampa Graduate Theses and Dissertations

Alcohol liver disease (ALD) is a major health concern throughout the world. Currently, in the United States, 17 million people suffer from alcoholism, of which 1.4 million people are receiving treatment [1, 2]. The link between ethanol metabolism, reactive oxygen species (ROS) and liver injury in ALD has been well characterized over the last couple decades [3-10]. Ethanol metabolism relies on the availability of the cofactor NAD+ for the oxidation of ethanol into acetate, consequently causing alterations in redox potential. Redox dysfunction within the mitochondria can affect multiple pathways important in maintaining cellular homeostasis. Chapter 1 provides an introduction to …