Digital Commons Network^™

The Newgeneratortm Decentralized Wastewater Treatment System For Non-Sewered Sanitation: Technology Advancement Through Field Evaluation And Modeling, Hsiang-Yang Shyu

USF Tampa Graduate Theses and Dissertations

Non-sewered sanitation systems (NSSS) offer innovative solutions to sanitation challenges in areas lacking basic facilities, utilizing advanced treatment technologies for on-site water reuse. The NEWgenerator (NG), an advanced NSSS developed at the University of South Florida under the Bill & Melinda Gates Foundation’s Reinventing the Toilet Challenge, integrates an anaerobic membrane bioreactor (AnMBR), an ion exchange-based nutrient capture system (NCS), and an electrochlorinator for final disinfection. This study builds on previous field trials of the NG system, focusing on developing, evaluating, and optimizing its water reuse capabilities through field trials, system dynamics modeling, and advanced monitoring techniques.

In the first …

Assessing Users’ Attention Classification Accuracy From Eeg Data, Gil Olenscki Neto

USF Tampa Graduate Theses and Dissertations

Determining whether a person is attentive while performing a task is a key factor for understanding why they are achieving specific results. In addition, tracking these results is an important aspect to improving them. Quantified self is a field that consists of self-monitoring to gain a better understanding of your habits, health, and overall well-being. Examples of this method include tracking sleep patterns, daily steps, mood swings, and food intake.

This thesis aims to explore the potential of using an innovative self-quantification method that utilizes a mobile application that leverages alpha, beta, and theta waves to assess college students' attention …

Migrant Advocates' Perceptions Of School-Based Collaboration, Michael Young

USF Tampa Graduate Theses and Dissertations

Migrant farmworker students are a marginalized group with unique needs. Federal law provides funding for Migrant Farmworker Advocates who support the educational and material needs of migrant farmworker students and their families in public schools. This exploratory study examines the question, how do migrant advocates collaborate with other professionals to support their students with graduation and transitioning to post-secondary opportunities? The study analyzes this unexplored professional relationship between migrant advocates and high school personnel and how they work together to serve migrant students. Data were collected through semi-structured single subject interviews from seven current or former Title I funded Migrant …

Artificial Intelligence Modeling Of Alzheimer's Disease And Environmental Science, Mohamed Abu Sheha

USF Tampa Graduate Theses and Dissertations

A data-driven statistical model operates as a mathematical illustration of a tangible issuefaced in reality, enabling the creation of predictions or decisions based on data. The process of utilizing probability and statistical principles in statistical models is essential for deriving meaningful conclusions from the data. The research conducted in this dissertation utilizes artificial intelligence (AI) models to integrate findings across health and environmental sci- ence.

The first research study in this dissertation, Alzheimer’s disease is a mental health issue and a brain aging dilemma that makes it difficult for older people to complete daily tasks without assistance. The physician uses …

Identification And Characterization Of Intrinsically Disordered Protein Regions, Guy Wayne Dayhoff Ii

USF Tampa Graduate Theses and Dissertations

This dissertation investigates protein intrinsic disorder and intrinsically disordered protein regions (IDPRs) through the development and application of advanced computational and experimental techniques. Chapter 1 provides an introduction to protein intrinsic disorder, outlining the historical context and fundamental concepts that highlight the importance of intrinsically disordered proteins (IDPs) and IDPRs in various biological processes. Chapter 2 focuses on the rapid prediction and analysis of protein intrinsic disorder. We introduce RIDAO (Rapid Intrinsic Disorder Analysis Online), a high-efficiency web-based tool that integrates multiple disorder predictors. RIDAO significantly outperforms existing predictors in computational efficiency, making it suitable for large-scale proteomic studies. We …

An Investigation Into Loneliness And Solitary Drinking In A University Sample, Daniel C. Faraci

USF Tampa Graduate Theses and Dissertations

Alcohol consumption tends to occur in social contexts and has been shown to increase prosocial behaviors and facilitate social connection. Simultaneously, socially excluded drinkers tend to increase or continue problematic levels of alcohol consumption when alone, possibly consuming alcohol as a replacement for desired but unavailable social connection. This investigation attempted to examine the relationship between loneliness (i.e., lack of perceived social connection) and subsequent alcohol consumption in solitary versus social contexts using ecological momentary assessment (EMA) techniques. University students recruited through a research subject pool who drank at least once per week were asked to respond to 28 short …

Design Of A Satellite Tracking Mobile App Using Flutter And Android Studio Ide, Audrey Tahwa

USF Tampa Graduate Theses and Dissertations

A pop-up free mobile application was developed utilizing one-minute intervals for positiontracking. Predictions are conducted off-line after the user has connected at least once. In In order to enhance data accuracy, the application includes a feature to download satellite data and update raw data to be used in prediction calculations. Additionally, users receive a notification when the application is ready for offline use.

Managing The Relationship Between Hispanic Voters And The State Of Florida: A Quantitative Survey Analysis, Selena M. Gonzalez

USF Tampa Graduate Theses and Dissertations

In recent years, the relationship between registered voters of minority groups and the government of the states they reside in has become increasingly complex due to controversial legislation proposed and often passed in these states. Specifically, some states have passed laws that make it more difficult for Hispanic/Latinx residents to live and work. In particular, Florida has enacted legislation that makes it more difficult for members of the minority groups to vote, drive, and gain access to healthcare. Much of this legislation impacts the Hispanic/Latinx community, which can influence perceptions of the relationship this racial minority has with Florida’s state …

Teachers' And School Directors' Perceptions Of The Benefits Of Arts-Integrated Instruction K-2: Before, During, And After Covid-19, Alison H. Mehler

USF Tampa Graduate Theses and Dissertations

The purpose of this study is to explore the experiences and perceptions of teachers who use arts-integrated instruction and their directors of K-2 students before, during, and after the unique period of online instruction during the COVID-19 pandemic, which began in March of 2020. Arts integration is a method of teaching in which students are taught comprehension of subject areas (i.e. – math, science, reading, social studies) through art forms. These art forms include music, theatre, dance, art, and writing. I collected he qualitative data for this research through virtual interviews with five female participants. I transcribed these interviews and …

Data-Driven Modeling Of Calcium Homeostasis And Bioenergetics In Alzheimer’S Disease, Down’S Syndrome And Leigh’S Syndrome., Abdul Rahim Umar

USF Tampa Graduate Theses and Dissertations

Disruption of Ca2+ homeostasis is implicated in the pathogenesis of several neurological conditions, including Alzheimer’s disease (AD), AD-like pathology in Down's Syndrome (DS) and Leigh’s Syndrome (LS). In astrocytes, disrupted intracellular Ca2+ signaling can compromise numerous brain functions, including synaptic transmission, neurovascular coupling, andbioenergetics. In our first project, we investigated the effects of brain extracts from AD patients on calcium signaling within cells and found that these extracts triggered a release of calcium within the cell, similar to synthetic components of amyloid beta plaques, a hallmark of AD. We developed a computational model to analyze how these changes in calcium …

An Evaluation Of The Premack Contingency To Increase Physical Activity In Teenagers With Autism Spectrum Disorder, Shreeya S. Deshmukh

USF Tampa Graduate Theses and Dissertations

The United States Department of Health and Human Services (2018) recommends that teenagers engage in physical activity to improve their cardiovascular health and muscle and bone strength. Yet, most teenagers with and without autism spectrum disorder do not meet the recommended guidelines for physical activity. Research related to promoting physical activity has evaluated group contingencies, reinforcement-based interventions, and antecedent interventions; however, these interventions are time-intensive, require many resources, or are ineffective. The purpose of this study was to extend Allen and Iwata (1980) by reinforcing completion of a low-probability exercise to a specified criterion with access to a high-probability exercise. …

The Influence Of Recycled Water On Microbial Source Tracking Techniques That Aim To Identify Untreated Sewage In Surface Waters, Aldo E. Lobos

USF Tampa Graduate Theses and Dissertations

Fecal pollution in recreational waters can introduce pathogens that cause increased human health risk, where exposure can occur during recreational activities such as swimming, diving, surfing, and fishing. Furthermore, human fecal pollution (i.e., sewage) can introduce nutrients and other harmful chemicals that may negatively affect the environment and aquatic species. Generally, sewage is considered the highest risk to human health compared to animal fecal pollution because it typically contains a high diversity of pathogens (including human specific viruses), antibiotic resistant bacteria and genes associated with antibiotic resistance. However, pathogens are difficult to detect due to their low concentrations in the …

The Discovery Of First Ret Protac With In Vivo Activity, Yafeng Wang

USF Tampa Graduate Theses and Dissertations

This report mainly discusses the development of RET Proteolysis targeting chimera PROTAC molecules based on Selpercatinib (LOXO-292) and Sulfono-γ-AApeptide PROTAC. A PROTAC molecule is a bifunctional molecule composed of two active domains and a linker. It works by inducing selective protein intracellular degradation. This technology was first discussed by Kathleen Sakamoto, Ray Deshaies and Craig Crews in 2001. Using various E3 Ligase, such as CRBN, pVHL, beta-TrCP1, Mdm2, DCAF15, DCAF16, RNF114, and c-IAP1, the PROTAC technology has been applied to several novel drug development,. Yale University licensed the PROTAC technology to Arvinas in 2013–14. For my research, Chapter one summarizes …

The Application Of Multi-Isotope Analysis To Assist In Geoprofiling Unidentified Decedents Within Florida, Liotta D. Noche-Dowdy

USF Tampa Graduate Theses and Dissertations

The biochemistry of human tissues can provide information for geoprofiling (geographic birthplace or migration patterns) of an unidentified decedent. Utilizing isotope analyses (both stable and radiogenic) from teeth, bone, nails, and/or hair reveals specific isotopic information that correlates to diverse geographic regions reflecting an individual’s birthplace and migration patterns. Isotope analysis of enamel and bone has been employed in bioarchaeology for decades to reconstruct the diet, health, and migration patterns of past populations. Isotope ratios measured from enamel can then be compared to isotope ratios measured from bone of the individual to track patterns of migration. The enamel from the …

Tuning Polymer Glass Formation Behavior And Understanding Time-Temperature Superposition Breakdown With Oligomeric Additives, Peijing Yue

USF Tampa Graduate Theses and Dissertations

The glass transition of polymer melts has been investigated for over a century. Even so, there are still many unanswered questions about the underlying physics. Countless theories were proposed to explain and define glass transition temperatures. More specifically, both the origins of the glass transition and underlying classification of glass as a state of matter remain unresolved. Time-temperature superposition (TTS) is one of the most widely used techniques to characterize the viscoelastic behavior of a material and the mechanical behavior and is employed to reduce the measuring time during characterization. Despite the widespread use of TTS, many authors have reported …

3d Organ-Scale Models Of Tumor Growth And Treatment, Rafael Ramon Bravo

USF Tampa Graduate Theses and Dissertations

To understand the dynamics of cancer, mathematical oncologists have developed models of tumor growth and treatment response. Some models are mechanistic and approach tumor growth at the cell-scale, focusing on the evolution of cancerous cells within the ecology of normal tissue, and are often simulated with agent-based modeling. Other models are more clinically motivated and model tumor growth operating at the organ-scale, using patient data to predict treatment response, and are often simulated with partial differential equations. We developed the Hybrid Automata Library which includes both agent-based modeling and partial differential equations for modeling at either of these scales. We …

Bayesian Analysis Of Hospital Service Quality: Pre- And Post-Covid, Ling Hu

USF Tampa Graduate Theses and Dissertations

The hospital sector is the largest revenue-generating industry in the United States, with a revenue of $1.4 trillion in 2022, accounting for 5.8% of the U.S. GDP. Its service quality profoundly impacts societal welfare, especially given the aging population reached 55.8 million in 2020 and is expected to reach 82 million by 2050. Therefore, multiple policies aim to incentivize sustained healthcare service quality improvements. As an integral component of the Hospital Value-Based Purchasing (HVBP) Program, the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey, administrated by the Centers for Medicare and Medicaid Services (CMS), serves as a cornerstone …

Development Of Decision-Support Tools For Water Resources Management In Coupled Human-Natural Systems, Edgar J. Guerrón Orejuela

USF Tampa Graduate Theses and Dissertations

Water is an indispensable resource for all forms of life. Water is a cornerstone for economic development, public health, and social well-being. However, increasing water demand and challenges posed by climate change, pollution, population growth, and land use change underscore the urgent need for effective water management strategies. To address these complexities and ensure the sustainable use of water resources, it is imperative to adopt science-based decision-support tools. These tools leverage data, models, and analytical techniques to provide valuable insights and recommendations that guide decision-makers in formulating evidence-based policies and practices.

Effective water management requires a comprehensive understanding of the …

Local Seismic Investigations In Arizona: Analysis Of A Low-To-Moderate-Magnitude Aftershock Sequence And A Pilot Study Of Monsoon-Driven Flash Floods, Kathryn Margo Dorn

USF Tampa Graduate Theses and Dissertations

Arizona encompasses a strikingly diverse array of geological terranes and physiographic terrain and consequently experiences a wide range of tectonic and meteorological phenomena, many of which generate distinctive seismic signals. For much of the past century, however, the state has largely lacked the style of dense seismic networks now prevalent in some regions of neighboring California, allowing myriad low-magnitude earthquakes and other subtle seismic sources to elude detection and characterization. In this dissertation, I utilize the high-resolution data of two temporary local seismic networks to investigate two such sources – the primarily low-magnitude but prolific aftershock sequence of the 29 …

Exploring Online Language Learning Activities And Intercultural Communicative Competence: Perspectives Of International Students, Moneera Abdulaziz Alsubaihi

USF Tampa Graduate Theses and Dissertations

Societies are increasingly aware of the need to connect and communicate globally. Thus, navigating diverse cultural contexts becomes critical, which necessitates intercultural competence—the skill of effective communication and understanding across cultures. As the digital age reshapes our interactions, online learning platforms have emerged as dynamic spaces that foster intercultural engagement and competency development. The purpose of this study was to explore this engagement and development through online English language activities that enhance international students' intercultural communicative competence (ICC) and language learning experience. This qualitative study aimed to provide a comprehensive understanding of international students' experiences in online English language courses, …

An Inference-Centric Approach To Natural Language Processing And Cognitive Modeling, Animesh Nighojkar

USF Tampa Graduate Theses and Dissertations

Reasoning over natural text is highly nuanced, and interpretations can vary widely depending on cultural background, financial status, age, gender, or even mood. This doctoral dissertation seeks to not only mimic human reasoning behaviors but also improve the task used in natural language processing (NLP) to capture naturalistic reasoning, known as the Natural Language Inference (NLI) task. NLI involves determining whether a hypothesis is true (entailment), false (contradiction), or indeterminate (neutral) based on a given premise. Initially, we will investigate the extent to which NLP systems designed to capture semantic equivalence actually measure meaning equivalence. After establishing that they do …

Gone Smishing: An Integration Of Decision-Making And Protection Motivation In The Context Of Identity Theft Victimization, Taylor S. Fisher

USF Tampa Graduate Theses and Dissertations

Methods of obtaining sensitive information from Internet users have evolved consistently as technology has advanced and millions of mobile device users communicate through text (SMS) messaging daily, making them a target for smishing attacks. Smishing (short for SMS phishing) is a form of cybercrime where an offender will send fraudulent text messages attempting to gather sensitive information or convince the user to click on a malicious link. These messages often appear legitimate and rely on tactics like convincing users that immediate action needs to be taken. Smishing has become so widespread that in 2020, the Texas Attorney General issued a …

The Asymmetric Total Synthesis Of Membranolide And Efforts Towards The Oxeatamides, Sean Bradley

USF Tampa Graduate Theses and Dissertations

Total synthesis is a discipline within organic chemistry that is a constant force that propels the field forward. In our lab, we have immersed ourselves within the field of total synthesis to gain access to complex natural products, perform SAR studies, as well as highlight interesting methodology. Within these endeavors, we have completed the first asymmetric synthesis of membranolide. This has allowed us to explore potential biofilm eradication in our efforts to develop novel therapeutics to combat the ESKAPE pathogens and multi-drug resistance. We have also begun to pursue the first asymmetric total synthesis of the oxeatamides. By utilizing our …

The Influence Of Childhood Trauma On Dna Methylation Patterns And Sex-Specific Cortisol Stress Reactivity: A Secondary Analysis, Isabella F. Correia

USF Tampa Graduate Theses and Dissertations

Childhood trauma has been shown to significantly impact physical and mental health outcomes, leading to conditions such as heart disease, diabetes, depression, and difficulties in decision-making and maintaining relationships. Exposure to such trauma has the potential to dysregulate an individual’s stress response system, resulting in abnormal cortisol levels. Many studies suggest a lasting impact of early-life stress on DNA methylation patterns and, separately, cortisol stress reactivity. In addition, there are known sex differences in exposure to childhood trauma and cortisol reactivity; yet studies to date have not investigated whether there is an association to DNA methylation. This study utilized a …

Media Regulatory Dynamics: A Case Study Of Taiwan’S National Communications Commission And Its Implications For Media Independence., Chih-Jeng (George) Huang

USF Tampa Graduate Theses and Dissertations

In alignment with the US-led regime that champions free speech, the Republic of China (Taiwan) has assumed a prominent role in upholding the freedom of expression stance in East Asia. Rooted in historical origins and institutional conflicts between Taipei and Beijing, Taiwan has established a democratic system, presenting a distinct contrast with the Beijing system, and showcasing an alternative Chinese economy that embraces liberalism. Nevertheless, as Beijing’s influence grows stronger globally, Taiwan’s democratic politics have become increasingly delicate and sensitive. In the winter of 2020, Taiwan faced a critical moment in its control over media freedom, highlighting the ongoing tensions …

Reimagining Web Design: Empowering Agency Of Specialized Audiences Through User-Centered Heuristics, Haley Jones

USF Tampa Graduate Theses and Dissertations

This research seeks to create an alternative model for website design that interrogates standardized, linear ways of knowing and being by placing the audience at the center of the web design process. This research contributed a reimagined approach to traditional and standardized web design heuristics by considering an audience-centric methodology that was practical and applicable for web design praxis to create equitable user experiences which can empower audiences to recall their own knowledge and experience to make meaning for themselves through a reimagining of knowledge-making processes in a network of digitized information. In perceiving the rhetorical choice in design of …

A Critical Analysis Of Latine School Psychology Graduate Students’ Socialization Experiences, Chelsea Salvatore

USF Tampa Graduate Theses and Dissertations

This study aimed to uplift and critically analyze the experiences and perspectives of Latine school psychology graduate students regarding their programs' socialization process. I sought to call out oppressive structures and to identify anti-racist practices described by participants. I intended for this to inform school psychology programs on oppressive structures they must dismantle and anti-racist practices that disrupt the status quo to support the well-being and success of Latine graduate students. Seven Latine school psychology graduate students participated in one or two semi-structured interviews. I employed thematic analysis to discover themes from participant interviews. Once themes were identified, I utilized …

Roles Of Mitochondrial Chchd2 And Gpcr-Associated Β-Arrestin2 In The Pathogenesis Of Lewy Body Disorders, Teresa R. Kee

USF Tampa Graduate Theses and Dissertations

Coiled-coil-helix-coiled-coil-helix domain containing 2 (CHCHD2) is a mitochondrial protein that plays important roles in cristae structure, oxidative phosphorylation, and apoptosis. Multiple mutations in CHCHD2 have been associated with Lewy body disorders (LBDs), such as Parkinson’s disease (PD) and dementia with Lewy bodies (DLB), with the CHCHD2T61I mutation being the most widely studied. We generated the first transgenic mouse models expressing human CHCHD2WT and the PD-linked CHCHD2T61I mutation driven by the mPrP promoter. CHCHD2T61I Tg, but not CHCHD2WT Tg mice exhibit perinuclear mitochondrial aggregates, neuroinflammation, and have impaired long-term synaptic plasticity associated with synaptic dysfunction. Dopaminergic neurodegeneration, a hallmark of PD, …

Resolving Antarctic Margin Paleoceanography For Two Different Timescales And Archives, Theresa M. King

USF Tampa Graduate Theses and Dissertations

Recent decades have seen increased rates of ice mass loss from Antarctic ice sheets, through thinning of many ice shelves around the periphery of the continent. The most vulnerable are the glacial systems that are marine-terminating and grounded below sea level, a characteristic that exposes these systems to sea level rise and warming oceans. Enhanced basal melting under the influence of warm ocean water masses can lead to thinning and retreat of glaciers, and ultimately to the acceleration of grounded ice loss. To contextualize current ice mass loss and contribute to accurate model projections for future retreat scenarios, it is …

Enhancing The Performance Of Interdependent Stormwater Drainage And Roadway Systems Under Future Conditions, Chao Ye

USF Tampa Graduate Theses and Dissertations

Flooding can cause extensive and devastating damage to human properties, including damage to homes, businesses, infrastructure systems, and personal belongings and it has become a threatening challenge during the past decades due to the massive damage brought to communities, infrastructures, and ecosystems. As climate change intensifies, the frequency and severity of flooding issues are expected to increase, exacerbating the existing flooding risks for vulnerable communities. Various approaches of modeling, optimizing, and designing for multiple levels of flooding problems have been adopted to deal with flooding control studies and research to alleviate the flooding risks on multiple levels of communities. This …