Digital Commons Network^™

Metal Organic Frameworks (Mofs) And Porous Organic Polymers (Pops) For Heterogeneous Asymmetric Catalysis, Youngran Ji

USF Tampa Graduate Theses and Dissertations

The administration of enantiopure drugs brings advantages such as improved efficacy, more predictable pharmacokinetics and reduced toxicity from the point of view of the pharmaceutical area.[1] For this reason, a tremendous amount of supply and demand for enantiomeric pure compounds has been shown not only in market, but industry and academia.[^2-4] According to the industry publication Genetic Engineering and Biotechnology News (GEN) in 2014, 22 billion dollars were accounted for enantiopure form of drugs such as Sovaldi® (Sofosbuvir), Crestor® (Rosuvastatin), and Advair® (fluticasone/salmeterol).

The fact that one enantiomer can be pharmacologically effective whereas the other enantiomer can be …

Quantifying The Interaction Of Wildlife And Roads: A Habitat And Movement Approach, Rebecca Whitehead Loraamm

USF Tampa Graduate Theses and Dissertations

There is a growing need to address the effects of roadway presence on wildlife. Not only do roads directly impact gene dispersal from a movement perspective, but they limit movement of the individual animal from a habitat perspective by presenting an artificial barrier between one area of viable habitat and another. For this reason it is becoming increasingly important to quantify contact between humans and wildlife and to develop better methods for mitigating these types of conflicts. Studying habitat connectivity and animal mobility in the context of roads can provide actionable information on how, where, and when these encounters might …

Altered Intraerythrocytic Development Phenotypes Of Artemisinin-Resistant Plasmodium Falciparum Confer A Fitness Advantage, Amanda Hott

USF Tampa Graduate Theses and Dissertations

Resistance to artemisinin combination therapies (ACTs) has emerged in southeast Asia threatening the most widely used treatment against antimalarial-resistant Plasmodium falciparum worldwide. Artemisinin resistance has been associated with a reduced rate of parasite clearance following treatment with an ACT and is attributed to increased survival of ring-stage parasites. Single nucleotide polymorphisms (SNPs) in kelch gene (K13) has been associated with delayed in vivo clearance half-life of artemisinin-resistant P. falciparum and is the only known molecular marker of resistance. The absence of reliable in vitro phenotypes for artemisinin resistance has limited our understanding of the resistance mechanism(s) and fitness costs, therefore …

Development Of Orally Bioavailable 4(1H)-Quinolones And 1,2,3,4-Tetrahydroacridin-9(10H)-Ones With Potent Anti-Malarial Activity, Jordany Richarlson Maignan

USF Tampa Graduate Theses and Dissertations

Although Malaria rates are on the decline due to the efforts of the World Health Organization and other organizations dedicated to the eradication of this disease, a relaxed attitude towards the development of new antimalarial entities would be flawed. Due to the emergence of resistance in the parasite, the almost 50% world-wide reduction in malarial death rates that have been produced over the past 15 years are threatening to be lost

New drugs are urgently needed and our approach focuses on the re-evaluation and optimization of the historic antimalarial ICI 56,780. Due to its causal prophylactic activity, along with its …

Relational Agency, Networked Technology, And The Social Media Aftermath Of The Boston Marathon Bombing, Megan M. Mcintyre

USF Tampa Graduate Theses and Dissertations

Agency is a foundational and ongoing concern for the field of Rhetoric and Composition. Long thought to be a product and possession of human action, rhetorical agency represents the most obvious connection between the educational and theoretical work of the field and the civic project of liberal arts and humanities education. Existing theories of anthropocentric rhetorical agency are insufficient, however, to account for the complex technological work of digitally enmeshed networks of humans and nonhumans. To better account for these complex networks, this project argues for the introduction of new materialist theories of distributed agency into conversations about agency within …

Theoretical Investigations Of Gas Sorption And Separation In Metal-Organic Materials, Tony Pham

USF Tampa Graduate Theses and Dissertations

Metal--organic frameworks (MOFs) are porous crystalline materials that are synthesized from rigid organic ligands and metal-containing clusters. They are highly tunable as a number of different structures can be made by simply changing the organic ligand and/or metal ion. MOFs are a promising class of materials for many energy-related applications, including H₂ storage and CO₂ capture and sequestration. Computational studies can provide insights into MOFs and the mechanism of gas sorption and separation. Theoretical studies on existing MOFs are performed to determine what structural characteristics leads to favorable gas sorption mechanisms. The results from these studies can provide …

Surface Science Studies Of Graphene Interfaces, Arjun Dahal

USF Tampa Graduate Theses and Dissertations

Interfaces between graphene and dissimilar materials are needed for making devices, but those interfaces also modify the graphene properties due to charge transfer and/or symmetry breaking. In this dissertation we investigate the technology of preparing graphene on different substrates and how the substrate influences the electronic properties of graphene.

Synthesizing large area graphene on late transition metals by chemical vapor deposition is a promising approach for many applications of graphene. Among the transition metals, nickel has advantages because the good lattice match and strong interaction between graphene/Ni(111) enables the synthesis of a single domain of graphene on Ni(111). However, the …

A Study Of Fe3O4 Magnetic Nanoparticle Rf Heating In Gellan Gum Polymer Under Various Experimental Conditions For Potential Application In Drug Delivery, Gabriel Marcus

USF Tampa Graduate Theses and Dissertations

Magnetic nanoparticles (MNPs) have found use in a wide variety of biomedical applications including hyperthermia, imaging and drug delivery. Certain physical properties, such as the ability to generate heat in response to an alternating magnetic field, make these structures ideal for such purposes. This study's objective was to elucidate the mechanisms primarily responsible for RF MNP heating and determine how such processes affect polymer solutions that might be useful in drug delivery. 15-20 nm magnetite (Fe₃O₄) nanoparticles at 0.2% and 0.5% concentrations were heated with RF fields of different strengths (200 Oe, 400 Oe and 600 …

Chemistry Graduate Teaching Assistants' Experiences In Academic Laboratories And Development Of A Teaching Self-Image, Todd Adam Gatlin

USF Tampa Graduate Theses and Dissertations

Graduate teaching assistants (GTAs) play a prominent role in chemistry laboratory instruction at research based universities. They teach almost all undergraduate chemistry laboratory courses. However, their role in laboratory instruction has often been overlooked in educational research. Interest in chemistry GTAs has been placed on training and their perceived expectations, but less attention has been paid to their experiences or their potential benefits from teaching.

This work was designed to investigate GTAs' experiences in and benefits from laboratory instructional environments. This dissertation includes three related studies on GTAs' experiences teaching in general chemistry laboratories. Qualitative methods were used for each …

The Interaction Of Feedback And Reward Contingency On Cardiovascular Reactivity During A Stressful Cognitive Task, Alvin B. Jin

USF Tampa Graduate Theses and Dissertations

Excessive sympathetic cardiovascular reactivity to stressful tasks is a risk factor for the development of cardiovascular disease (CVD). Many populations with a greater risk for CVD instead demonstrate blunted cardiovascular reactivity to stressful tasks. The motivational intensity theory identifies how motivation and effort influence sympathetic reactivity. Blunted reactivity may be a potential index of motivational dysregulation, which leads to poor behavioral decisions such as excess smoking or alcohol use, in turn increasing the risk for CVD. The current study sought to demonstrate how inhibited effort due to poor ability feedback with a low-contingency reward could directly increase the risk for …

Evaluation And Application Of Instruments Measuring Spatial Ability And Attitude For College Chemistry Students, Xiaoying Xu

USF Tampa Graduate Theses and Dissertations

Student performance in college chemistry courses remains a concern for educators seeking to help improve the future STEM workforce. Besides math ability and prior chemistry knowledge, spatial ability and attitude toward chemistry have been considered as important factors influencing college chemistry performance. This work includes five studies and uses data collected from instruments to examine the relationships of these two factors - spatial ability and attitude - with student chemistry performance, and provides psychometric evidence for using the Purdue Visualization of Rotations test (ROT) and Attitude toward the Subject of Chemistry Inventory (ASCIv2) to measure these two factors, respectively, in …

High Dimensional Non-Linear Optimization Of Molecular Models, Joseph C. Fogarty

USF Tampa Graduate Theses and Dissertations

Molecular models allow computer simulations to predict the microscopic properties of macroscopic systems. Molecular modeling can also provide a fully understood test system for the application of theoretical methods. The power of a model lies in the accuracy of the parameter values which govern its mathematical behavior. In this work, a new software, called ParOpt, for general high dimensional non-linear optimization will be presented. The software provides a very general framework for the optimization of a wide variety of parameter sets. The software is especially powerful when applied to the difficult task of molecular model parameter optimization. Three applications of …

Exploring Variability In Population Dynamics And The Influence Of Environmental Factors On Recruitment Of An Estuarine Fish, Elizabeth Herdter Smith

USF Tampa Graduate Theses and Dissertations

The focus of this dissertation was to explore variability in population dynamics and environmental factors influential to recruitment of spotted seatrout in Florida with the end goal of testing the incorporation of select environmental variables into the current regional stock assessment models for spotted seatrout. In Chapter 2, I compared the age and size structure of six estuary populations of this species and determined whether there was significant spatial covariation in recruitment. The results of this chapter indicated that the dynamics of each local estuary population are governed more likely by environmental factors than genetic similarities. Further, they suggest that …

Metallopeptides From Design To Catalysis: Structure, Oxidative Activities, And Inhibition Studies Of Designed And Naturally Occurring Metallopeptides, Alaa Hassan Hashim

USF Tampa Graduate Theses and Dissertations

Structural and mechanistic complexities of copper-dioxygen systems have attracted much attention in the field of bioinorganic chemistry, both in model systems and trapped protein intermediates. The research presented herein is focused on model and naturally occurring metallopeptide systems, from its design to catalysis. Copper is used as the coordinating metal ion, with cobalt and zinc as probes for metal binding. The bioinorganic chemistry of copper proteins and its coordination and spectroscopic properties are briefly discussed in chapter 1. The next two chapters are centered on the de novo design of a minimalistic metallopeptide system with an amino acid sequence of …

Mantle-Crust Interaction In Granite Petrogenesis In Post-Collisional Settings: Insights From The Danubian Variscan Plutons Of The Romanian Southern Carpathians, Ciprian Cosmin Stremtan

USF Tampa Graduate Theses and Dissertations

The issue of granite petrogenesis plays a key role in our overall understanding of the growth and differentiation of continents, as well as in our ability to unravel the tectonic histories of orogenic belts. Granites are ubiquitous magmatic products found in almost all tectonic settings: oceanic and continental rifts (i.e., plagiogranites - extreme basalt differentiates), active continental margins (e.g,. the granitic batholiths of central and southern Andes), continent-continent collision zones (e.g., the orogenic batholiths of the Himalayas, Western Anatolia), post-collisional settings (e.g., the Variscan provinces of Europe), complex within-plates settings (e.g., Limmo massif, Afar, Ethiopia). Furthermore, granitoids are characterized by …

Co(Ii) Based Metalloradical Catalysis: Carbene And Nitrene Transfer Reactions, Joseph B. Gill

USF Tampa Graduate Theses and Dissertations

Radical chemistry has attracted a large amount of research interest over the last few decades and radical reactions have recently been recognized as powerful tools for organic synthesis. The synthetic applications of radicals have been demonstrated in many fields, including in the synthesis of complex natural products. Radical reactions have a number of inherent synthetic advantages over their ionic counterparts. For example, they typically proceed at fast reaction rates under mild and neutral conditions in a broad spectrum of solvents and show significantly greater functional group tolerance. Furthermore, radical processes have the capability of performing in a cascade fashion, allowing …

Magneto-Optical Kerr Eect Study Of Magnetic Anisotropy In Soft Ferromagnets, Tatiana Marie Eggers

USF Tampa Graduate Theses and Dissertations

The continued progress of modern information technology relies on understanding the influence of magnetic anisotropy on magnetic thin films. In this work, two sources of magnetic anisotropy are examined in two different soft ferromagnets: a uniaxial anisotropy induced during the fabrication of Ni₈₀Fe₂₀ and exchange anisotropy, or exchange bias, which occurs at the interface of Ni₇₇Fe₁₄Cu₅Mo₄/Fe₅₀Mn₅₀ bilayer. A home-built Magneto-optical Kerr effect magnetometer is used to measure the magnetic response of the soft ferromagnetic films and details of its construction are also discussed. A simple model …

Performance Evaluation And Integrated Management Of Airport Surface Operations, Qing Wang

USF Tampa Graduate Theses and Dissertations

The demand for aviation has been steadily growing over the past few decades and will keep increasing in the future. The anticipated growth of traffic demand will cause the current airspace system, one that is already burdened by heavy operations and inefficient usage, to become even more congested than its current state. Because busy airports in the United States (U.S.) are becoming "bottlenecks" of the National Airspace System (NAS), it is of great importance to discover the most efficient means of using existing facilities to improve airport operations.

This dissertation aims at designing an efficient airport surface operations management system …

Task-Based Robotic Grasp Planning, Yun Lin

USF Tampa Graduate Theses and Dissertations

Grasp should be selected intelligently to fulfill different stability properties and manipulative requirements. Currently, most grasping approaches consider only pick-and-place tasks without any physical interaction with other objects or the environment, which are common in an industry setting with limited uncertainty. When robots move to our daily-living environment and perform a broad range of tasks in an unstructured environment, all sorts of physical interactions will occur, which will result in random physical interactive wrenches: forces and torques on the tool.

In addition, for a tool to perform a required task, certain motions need to occur. We call it "functional tool …

Top-Down Processes In Simulated Combined Electric-Acoustic Hearing: The Effect Of Context And The Role Of Low-Frequency Cues In The Perception Of Temporally Interrupted Speech, Soo Hee Oh

USF Tampa Graduate Theses and Dissertations

In recent years, the number of unilateral cochlear implant (CI) users with functional residual-hearing has increased and bimodal hearing has become more prevalent. According to the multi-source speech perception model, both bottom-up and top-down processes are important components of speech perception in bimodal hearing. Additionally, these two components are thought to interact with each other to different degrees depending on the nature of the speech materials and the quality of the bottom-up cues. Previous studies have documented the benefits of bimodal hearing as compared with a CI alone, but most of them have focused on the importance of bottom-up, low-frequency …

Channel Analysis And Estimation And Compensation Of Doppler Shift In Underwater Acoustic Communication And Mitigation Of Ifi, Isi In Ultra-Wideband Radio, Sadia Ahmed

USF Tampa Graduate Theses and Dissertations

Water occupies three fourth of earth's surface. The remaining one fourth is land. Although human habitats reside on land, there is no denying of the vital connection between land and water. The future sustainability of human species on this planet depends on wise utilization of all available resources, including that provided by the vast water world. Therefore, it is imperative to explore, understand, and define this massive, varying, and in many areas, unexplored water domain.

The water domain exploration and data collection can be conducted using manned or unmanned vehicles, as allowed by the water environment. This dissertation addresses three …

Short- And Long-Term Trends In Ecological Interactions: From Predator-Prey Interactions To Phanerozoic Diversification, Subhronil Mondal

USF Tampa Graduate Theses and Dissertations

During the last two decades, a broad spectrum of short- and long-term studies on different taxonomic groups has enriched our understanding about how dynamics of taxonomic and ecological diversification have changed through geologic time. There are two major issues that have impacted these studies: the quality and quantity of data used are often insufficient in various ways and the methods used may produce results that are more equivocal than supposed. To investigate these issues more fully, this dissertation focuses on studies on two major aspects: 1) short-term studies examining the nature of successful and unsuccessful predatory attacks on Plio-Pleistocene bivalves; …

Predicting Adolescents' Academic Achievement: The Contribution Of Attention And Working Memory, Diane Elizabeth Napier

USF Tampa Graduate Theses and Dissertations

The present study examined the direction and strength of the relation between three different areas academic achievement and working memory with adolescent students. The data analyzed included ratings for inattention, a diagnosis of ADHD (or not), and demographic information for race/ethnicity. Fifty children aged 11 to16 years of age participated in the study. Participants were recruited from several middle schools, homeschooling networks, and churches from a southeastern state of the United States. Each participant completed a standardized achievement test, a behavioral rating scale, and visual and verbal working memory tests. The research questions investigated: 1) the relation between visual and …

"Choosing My Words Carefully": Observing, Debriefing, And Coaching Four Literacy Teachers' Through Their Lessons, Iveta Maska

USF Tampa Graduate Theses and Dissertations

A safe environment, conducive to productive and transparent conversations, makes possible the improvement of literacy practices and strengthens teacher/administrator relationships for more honest and vulnerable conversations. In this autoethnographic intrinsic case study I conducted a self-study of my use of language and communication with four literacy teachers during debrief, after classroom walkthroughs, when coaching each on literacy practice. Furthermore, the component under investigation was the debrief meeting where dialogue is the key ingredient for discussing teacher classroom practice. The study was approached through identifying characteristics from my personal and professional background, to my interactions with the four literacy teachers and …

Thermal Assessment Of A Latent-Heat Energy Storage Module During Melting And Freezing For Solar Energy Applications, Antonio Miguel Ramos Archibold

USF Tampa Graduate Theses and Dissertations

Capital investment reduction, exergetic efficiency improvement and material compatibility issues have been identified as the primary techno-economic challenges associated, with the near-term development and deployment of thermal energy storage (TES) in commercial-scale concentrating solar power plants. Three TES techniques have gained attention in the solar energy research community as possible candidates to reduce the cost of solar-generated electricity, namely (1) sensible heat storage, (2) latent heat (tank filled with phase change materials (PCMs) or encapsulated PCMs packed in a vessel) and (3) thermochemical storage. Among these the PCM macro-encapsulation approach seems to be one of the most-promising methods because of …

Social-Emotional Strengths And Academic Outcomes In Kindergarten Students, Bryan B. Bander

USF Tampa Graduate Theses and Dissertations

Social-emotional competence has received increased attention as being critical to a student's success in the classroom. Social-emotional strengths are multidimensional and include assets such as social competence, self-regulation, empathy, and responsibility; however, previous research has not investigated which of these strengths contribute most to a student's academic success. Additionally, limited research has investigated the use of multiple informants (e.g., parents and teachers) to determine whose perceptions are more predictive of academic achievement in kindergarten students. This study examined the relationship between social-emotional strengths, as rated by parents and teachers on the SEARS (Merrell, 2011), and academic outcomes, using the AIMSweb …

Verification And Comparison Of Two Commonly Used Numerical Modeling Systems In Hydrodynamic Simulation At A Dual-Inlet System, West-Central Florida, Ming Xie

USF Tampa Graduate Theses and Dissertations

Numerical modeling systems are very important tools to study tidal inlets. In order to test its capability and accuracy of solving multi-inlet system problems, this study selected two widely used numerical modeling systems: Coastal Modeling System (CMS) and Delft3D Modeling Package. The hydrodynamics modules of the two modeling systems were tested at John's Pass and Blind Pass, Florida, a dual-inlets system, based on a similar modeling scheme. Detailed bathymetric surveys and hydraulic measurements were conducted to collect water depths, tide conditions, wave and current velocities as the input data as well as verification data for the models.

A comparison study …

Growth Rates In Gulf Of Mexico Red Snapper, Lutjanus Campechanus, Before And After The Deepwater Horizon Blowout, Elizabeth Shea Herdter

USF Tampa Graduate Theses and Dissertations

The Deepwater Horizon blowout occurred on April 20^th, 2010 and released nearly 5 million barrels of crude oil into the northern Gulf of Mexico causing pollution of the water and sediment inhabited by many fishes for at least 87 days while the wellhead went uncapped. Populations of the Gulf of Mexico Red snapper, Lutjanus campechanus, an important fish to the ecology and economy in the region, exhibit affinity to shallow water oil infrastructure such as the Deepwater Horizon making them especially vulnerable to crude oil contamination. The objective of this study is to determine growth of Red …

Polycyclic Aromatic Hydrocarbon Metabolites As A Biomarker Of Exposure To Oil In Demersal Fishes Following The Deepwater Horizon Blowout, Susan Susan Snyder

USF Tampa Graduate Theses and Dissertations

The Deepwater Horizon blowout occurred on April 20th, 2010, releasing 4.9 million barrels of Louisiana crude oil into the Gulf of Mexico (GoM). Subsequent to the Deepwater Horizon blowout, sediment cores revealed oil on the northern GoM seafloor and abnormal skin lesions were seen in GoM fishes. Exposure to polycyclic aromatic hydrocarbons (PAHs), a component of crude oil, in fish has been associated with many sublethal effects, including cancer and population-level effects. Using a biomarker of exposure to PAHs, this thesis evaluates inter-species, temporal and spatial differences in exposure to hydrocarbon contamination between three species of fish with varying levels …

Use Of A Towed Camera System For Estimating Reef Fish Populations Densities On The West Florida Shelf, Sarah Elizabeth Grasty

USF Tampa Graduate Theses and Dissertations

Reef fish species tend to reside over high relief habitat which makes them difficult to sample with traditional gears such as nets and trawls. Therefore, implementing and understanding the strengths and weaknesses of new approaches which incorporate acoustic and optical methods has become a priority for reef fish stock assessment. Beginning in June of 2013, a towed camera system known as the Camera-Based Assessment Survey System (C-BASS) has been used to visualize over 500 kilometers of transect and record more than 80 hours of video over several habitats in the Gulf of Mexico. Surveys have been completed on the West …