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The Inescapable Effects Of Discourse As Knowledge And Power: Refugee Youth’S Resistance To “The System” In Pursuit Of Higher Education, Fallon Puckett

Theses and Dissertations

Employing a Foucauldian inflected analytic framework, I examine how youth resettled in and around Unity, NC, ambivalently managed racializing discourses associated with being ‘refugee’ as they pursued access to higher education (HE). Like many scholars who are drawn to post-structuralist concepts, I understand ‘discourse’ to be a form of knowledge and power, which operates through institutions implicated in advancing forms of self-government. In my video-conferenced interviews with youth they revealed cogent interpretations of the many ways these different U.S. governmental (and some non-governmental) institutions operated in their lives as “the System.” In the particular case of refugee youth, they used …

Transgressive Migrations: Gender Roles, Space, And Place In American Novels, 1900-1999, Selena Gail Larkin

Theses and Dissertations

In this dissertation, I examine how gender roles combine with changes in space and place to affect women protagonists in twentieth-century American literature. I argue that as these characters migrate, the (self-)perception of their identities shift. Particularly, their outward performances as well as their internal awareness change. My analysis concentrates on the novel genre because of specific characteristics—plot, characterization, and narration. The chosen literary works on which I focus are The Grapes of Wrath (1939), Quicksand (1928), Their Eyes Were Watching God (1937), The Dollmaker (1954), and Under the Feet of Jesus (1996).

Concepts that I …

Previvor And High-Risk Breast Cancer Patients’ Opinions On A Specialized Management Clinic, Madeleine Nicole Tjoelker

Theses and Dissertations

Approximately 5-10% of cancers are thought to be hereditary, caused by pathogenic variants in genes associated with inherited cancer syndromes. Previvors, individuals who have a higher predisposition to cancer due to genetic or other risk factors, have specific healthcare and psychological needs that may be better served by a specialized management clinic. This study compared the experiences of previvors who had access to a specialized management clinic with those who did not, in order to better understand the unique needs of previvors. This study utilized a mixed methods design including an online survey (N=26) and semi-structured phone interview …

Sanctuary Poetics And Contemporary Us Culture, Alex Howerton

Theses and Dissertations

Sanctuary Poetics and Contemporary US Culture argues that contemporary poets of color create spaces of safety, relation, and justice through the act of writing as resistance itself. Sanctuary Poetics discusses poetry responding to the myriad crises of our contemporary moment, and considers how poets, through formal techniques such as ekphrasis or synecdoche, envision moments of shelter and connection that provide necessary relief to imperiled populations. I introduce the idea of a sanctuary poetics through Amanda Gorman’s recent poem “The Hill We Climb,” performed at Joseph Biden’s inauguration. The first chapter covers citizenship and the work of the Undocupoets, a multiracial …

Fortnightly Effects Of Urea Additions On Cyanobacteria In A Stormwater Detention Pond, Halley Carruthers

Theses and Dissertations

Increased urban and suburban population growth along the South Carolina (SC) coast has led to a rise in impervious surfaces, altering the course of stormwater runoff events. The construction of stormwater detention ponds (SDPs) is one of the many ways to best mitigate the flow of this water. In their function as natural pollutant traps, SDPs often contain increased levels of nutrients (nitrogen, N and phosphorus, P), which can lead to eutrophication. Under these high eutrophic conditions, primary production is overstimulated, and the formation of phytoplankton blooms, including harmful algal blooms (HABs) can occur. In recent decades, the forms of …

Cult Of The Day Moon, Markham Sigler

Theses and Dissertations

This book is a collection of short stories and miniatures. A variety of themes and styles are employed. Themes include environmentalism, the family, late capitalism, and alienation. Styles include surrealism, neorealism, hysterical fiction, and science fiction, as well as speculative fiction.

Exploring Effects Of Sample Storage, Preparation, And Tissue Type On Fourier Transform-Near Infrared Spectroscopy (Ft-Nirs) Ageing Across Fish Taxa, Keith Fuller

Theses and Dissertations

The accurate determination of age for fish is a vital part of both populationmanagement and ichthyological research. However, the methods which are primarily employed to age fish can be difficult, time consuming, inaccurate, or some combination thereof. Most ageing is currently done via hard parts (such as otoliths, vertebrae, or scales) which are read in a manner similar to tree rings with markings corresponding to known or presumed periods of time. Recently, Fourier transform-near infrared spectroscopy (FT-NIRS) has been investigated as a novel tool to age fish more quickly and objectively. This method works by recording the vibrational frequencies of …

Treatment Of Hiv-1 Associated Neurocognitive Disorders Through Mechanisms Of Neurogenesis With 11-Hour Voluntary Running Wheel Exposure, Alex Steiner

Theses and Dissertations

Individuals with HIV-1 taking combined antiretroviral therapy (cART) live longer with less morbidity associated with the infection. The increase in lifespan has created a critical need for the deterrence of HIV-1 associated neurocognitive disorders (HAND) reported in the aging population. Previous reports indicate that the HIV-1 infection may cause impairment in neurogenesis, leading to many of the cognitive deficits seen. The current paper proposes that exercise, as defined by voluntary wheel running, would be a potent inducer of neurogenesis that results in the neuro-restoration of CNS properties and cognitive functioning. Each animal had free access to 11-hour nocturnal wheel-running seven …

Resrouce Allocation And Visual Communication In Lepidoptera, Linda Nicole Fipps

Theses and Dissertations

Visual signals in the form of wing color, size, shape, pattern, and UV reflectance play an important role in the mating and reproductive strategies of diurnal butterflies. Wing-based visual signals are linked to different functions and can be acted on by a variety of selective pressures. In a comprehensive look at the literature on the visual communication strategies of lepidopteran species, I look at how visual signals, most notably color, are used, generated, and perceived. I discuss the costs and benefits of those strategies for the fitness of butterflies and moths and look at lepidopteran visual communication through the lens …

Role Of Ahr Ligands In Immune Modulation To Suppress Inflammation Through The Regulation Of Microrna And Gut Microbiome, Osama Azeldeen Abdulla

Theses and Dissertations

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor and an environmental sensor that is highly conserved evolutionarily. It was first discovered in the early 1970s for its ability to bind with high affinity to 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), an environmental pollutant and induce a xenobiotic-metabolizing enzyme known as aryl hydrocarbon hydroxylase (AHH). AhR was shown to regulate TCDD-mediated toxicity against a variety of tissues including the immune system. More recently, AhR has been characterized as key regulator of the immune system, specifically the differentiation of T cells. Also, several AhR ligands have been characterized in addition to TCDD such as …

Automating And Implementing Complex, Multistep Sample Preparation Processes To Generate Reproducible Proteomic And Phosphoproteomic Data, Brian Todd Mullis

Theses and Dissertations

Phosphorylation is the most common post-translational modification that occurs within the cell and is intricately involved in many biological processes. It is important to understand the roles that protein kinases and phosphatases play by mapping protein phosphorylation as many disease states stem from aberrant signaling events. With the advent of modern mass spectrometry (MS), researchers are now provided with more complex phosphorylation patterns from thousands of proteins in each mass spectrometric analysis. Further developments in quantification techniques, such as stable isotope labeling with amino acids in cell culture (SILAC) and label-free quantitation, have allowed researchers to reliably quantify changes to …

Effect Of Oxidative Stress On Lifespan And Cellular Survival, Benedicth Onyeka Ukhueduan

Theses and Dissertations

When cells experience oxidative stress, the integrated stress response (ISR) signaling pathway is activated. One of the first outcomes of such ISR-activated response is to temporarily halt protein synthesis, which aids in cellular recovery. However, if cells cannot recover from the stress, they activate the cell death pathways which kills the affected cells, usually by apoptosis, which can then lead to either acquisition or prevention of diseases depending on the situation. In physiological aging, a compromised stress response is observed as an organism ages, which leads to disrupted homeostasis and elevated risk of disease. Thus, longevity of an organism is …

The Impact Of Collective Efficacy And Collective Inquiry On Closing The Achievement Gap, Anne Marie Yarborough

Theses and Dissertations

The purpose of this two-phased, mixed-method action research study was to investigate the impact of a professional learning community’s collective teacher efficacy and their practice of collective inquiry in closing the achievement gap of eighth-grade social studies English language learners. The research questions guiding this research: 1. How and to what extent will collective inquiry impact collective efficacy among teachers? 2. How and to what extent will a professional learning community's collective efficacy impact student achievement on the 8th-grade social studies state assessment for English language learners?

Social cognitive theory and adult learning theory provided the theoretical foundation for this …

The Impact Of Plcs On Teacher Self-Efficacy, Paula Lynn Taylor

Theses and Dissertations

This study examined the impact of a professional learning community on teacher self-efficacy at Elm Primary School in rural South Carolina. The literature suggests that PLCs are an amenable approach to improving individual teacher efficacy beliefs and classroom practices (Corcoran, 2007; Guskey, 2003). For this study, self-and collective efficacy were measured using Likert-scale surveys, semi-open ended interviews, participant journals, observation and field notes, and artifacts. Both qualitative and quantitative data were collected, making this a mixed-methods study.

The results confirmed and expanded understandings about PLCs' impact on efficacy. Participants recognized goal setting, actions, and results as important qualities of collaboration …

Formation Of A Professional Learning Community To Promote Metacognitive Teaching: An Action Research Study, Margaret Gregg Long

Theses and Dissertations

This mixed-methods action research study examined how implementing a Professional Learning Community (PLC) supports the development of metacognitive teaching. Participants were ten technical college science instructors. While PLCs are common in K-12 education, they are less employed at the postsecondary level. There is a gap in the literature regarding PLCs in the context of postsecondary education, and the metacognition of postsecondary level educators. A PLC was used as an intervention over a 15-week semester to aid in the development of metacognitive teaching. Instructor use of metacognition was assessed using pre- and post-surveys, questionnaires, and interviews. The study's results supported literature …

A Multilevel And Spatial Analysis Of Oral And Pharyngeal Cancer In South Carolina, Deborah M. Hurley

Theses and Dissertations

Objective: Disparities in the distribution of oral and pharyngeal cancer exist worldwide. This is also true in the United States and in South Carolina. Differences exist in oral and pharyngeal cancer stage and survival by race and sex, with higher incidence rates for Whites but higher proportions of late-stage cancer and lower survival for Blacks. This study was conducted to evaluate whether any differences exist in the spatial distribution of oral and pharyngeal cancer stage at diagnosis and survival, and to evaluate the association of income inequality, material deprivation and other measures of social determinants of health (contextual risk factors) …

Evaluation Of A Clinic-Based Peer Navigation Program (Pnp) For African Americans Living With Hiv In South Carolina, Kimberly Butler Willis

Theses and Dissertations

Peer navigation programs have been identified as a potential motivator in care engagement and retention for patients living with HIV, although the data is inconsistent. HIV management requires important disease management considerations and innovative approaches for patient care. Medication advancements and technology have drastically improved care for most patients living with this chronic disease; yet African Americans contract, live with, and die because of HIV-related complications at disproportionately higher rates compared to their White peers.The purpose of this exploratory mixed-methods outcome evaluation is to: (1) determine if peer navigation is a viable intervention to improve three key HIV care metrics: …

Plasmids Bring Novel Functions To Caulobacter Genomes, Taylor Howell Carter

Theses and Dissertations

Caulobacter is a well-studied bacterial genus, but little is known about the plasmids that are found in some wild Caulobacter isolates. I identified nine plasmids from seven different Caulobacter strains and grouped them based on their size and the similarity of their repABC, parAB, and mobAB genes. Protein pathway analysis of the genes on the K31p1, and K31p2 plasmids showed many metabolic pathways that would enhance the metabolic versatility of the host strain. In contrast, the CB4 plasmid contained 21 heavy metal resistance genes organized into 9 operons. The majority of the CB4 heavy metal resistance genes code for …

Design And Synthesis Of Macrocyclic Peptide Braf-Wt Dimerization Inhibitors For The Treatment Of Metastatic Melanoma, Chad Mulloy Beneker

Theses and Dissertations

In cases of metastatic melanoma, BRAF is frequently mutated to the V600E oncoprotein causing uncontrolled cell proliferation driven by the MAPK-ERK pathway. There are several BRAF inhibitors, such as vemurafenib, which are FDA approved, but patients treated with these Type-I kinase inhibitors frequently observe relapse under mutant RAS and BRAF-wt conditions due to paradoxical activation. The mechanism of this resistance occurs through binding of the inhibitor to BRAF-wt initiating conformational changes which leads to BRAF dimerization. Once in the dimerized state, the inhibited monomer induces allosteric transactivation of the second monomer. This drug-induced activation of BRAF in cells with mutant …

Mechanism Of Therapeutic Efficacy Of New Drugs In Glioblastoma, Firas Hameed Khathayer

Theses and Dissertations

Glioblastoma is the most malignant and prevalent brain tumor in adults. It can grow and spread quickly causing harm to brain health. The deregulation of epigenetic mechanisms is considered the main agent in the developing of GBM. One of the enzymes involved in epigenetic alternation and cancer development are histone deacetylases enzyme (HDAC) by removal acetyl group from histone and create condensed chromatin that suppresses transcription gene to histone and non-histone proteins involved in tumorigenesis. Histone deacetylase inhibitors (HADCi) are the most common therapeutic methods for many types of cancer treatments. In the present study, we used relative HDAC inhibitor …

Health Communication Blindspot: A Case Study Of Harmful Algal Blooms In The South (Habits), Jaron Hoani King

Theses and Dissertations

A Harmful Algal Bloom (HAB) is a complex natural event that occurs when algae is in its growth stage and creates a harmful toxin as waste. HABs create both ecologic and public health challenges. The hypothesis of this thesis is that state and federal governments have different readability scores when compared side-by-side as measured by Simple Measures of Gobbledygook (SMOG). Because governments are the entity that most often claims responsibility for shared resources, this case study represents a snapshot of current governmental messaging about HABs in the South Atlantic states. These states have a long history of HAB events in …

The Impact Of Prioritization Of Independent Reading On Male, Struggling Adolescent Readers’ Engagement, Motivation, And Achievement, Meagan Wagner

Theses and Dissertations

To become better readers, students must read more and more, increasing the volume, complexity, and variety of books chosen. While independent reading is the best avenue by which to do this, many teachers still struggle to devote their limited instructional time to independent reading. Specifically addressing the context of my school, there was a clear distinction in gender and reading: boys were falling behind, less engaged, less motivated to read than girls. This research aimed to address the gender gap in reading by making independent reading a priority in the classroom. As a case study, five male eighth graders were …

Sleep Quality And Prevalence Of Anxiety And Depression In Young Adults With Concussion History, Jessica Barrack

Theses and Dissertations

Background: Concussions are a growing public health concern, and emerging long-term health risks may negatively impact an individual’s quality of life. With concussions, there can be a multitude of signs and symptoms, but frequent long-term sequelae of concussions including mood disturbances (e.g. trait anxiety and depression) and sleep disturbances (e.g. difficulties initiating and maintaining sleep) are given less attention. Few clinicians address mood and sleep disturbances in their concussion assessment and management plan, potentially placing individuals at risk for prolonged disturbances beyond recovery. Purpose: To examine the relationship between sleep disturbances (sleep quality) and mood disturbances (trait anxiety and depression) …

Use Of Flash Flaming Technology To Improve Seed Handling And Delivery Of Winterfat (Krascheninnikovia Lanata), Mitchell Grant Thacker

Theses and Dissertations

Ecological restoration of rangelands using wild-collected seeds can be challenging due to low seed quality, inconvenient seed anatomy, and poor plant establishment. In North America, the half-shrub winterfat (Krascheninnikovia lanata) is a valuable protein-rich forage for wildlife and livestock. Seeds of this species are contained in one-seeded fruits enclosed in four fluffy, silky bracts. While the seeds can be removed from the bracts, it is not recommended as the bracts are thought to help protect the seed and aid in germination and seedling growth. However, bracts of winterfat make it difficult to incorporate this species within a seed mix because …

Weekly One-Day Water-Only Fasting Interventional Trial For Low-Density Lipoprotein Cholesterol Reduction (Wonderful), Ciera Lynn Bartholomew

Theses and Dissertations

Purpose: Fasting has been promoted as a method of preventing disease and aging for thousands of years. With heart disease being a leading cause of death in the U.S., researchers have explored the effects of fasting on variables that influence cardiovascular disease (CVD), like LDL cholesterol. Therefore, the purpose of this study was to assess the effects of weekly water-only fasting on LDL cholesterol (LDL-C) in men and women with metabolic risk factors for CVD. Methods: This study was a randomized control trial in adult men and women. Participants were randomized to fasting (treatment) or normal diet (control). The fasting …

"I Thought That We Could Nurture The Nature Out Of Our Son": Making Meaning Of Parenting In The Narratives Of Parents Of Children In Residential Treatment, Jared V. Worwood

Theses and Dissertations

This study implements relational dialectics theory to explore the meaning of parenting from the perspective of parents who had enrolled a child in a residential treatment program. Contrapuntal analysis of six interviews revealed two discourses competing to make meaning of parenting. The Discourse of Demanding Parenting Ideals (DDPI) consisted of two themes: relentless sacrifice and complete responsibility, whereas themes of boundary-setting and acceptance compose the Discourse of Realistic Best Effort (DRBE). Discursive interplay between these discourses occurred in the forms of diachronic separation, synchronic interplay, and discursive transformation to make meaning of parenting and hold theoretical and practical implications.

Balancing Identities: A Thematic Analysis Of The Ideology Of Professionalism And Its Effect On Stigmatized Cultural Groups, Amber Allen

Theses and Dissertations

With the recent political climate, race has been an important topic of discussion and how the systems of our society influence your movement through life based on said race. The system of interest of this thesis of that of employment and the themes of what it means to be and act professional. Traditionally, these themes are centered around whiteness and the employees’ ability to adapt to these standards placed on the organization in which they work. Using critical race theory as the theoretical lens, this thesis uses a dialogic approach to convey the stories and testimonies of members of the …

"I Understand, Honey": Perceived Spousal Empathy's Moderating Influence On The Links Between Depression And Marital Satisfaction And Marital Satisfaction And Physical Health, F. Javier Celestino

Theses and Dissertations

An adapted version of the Vulnerability-Stress-Adaptation model was used as a theoretical guide for this study, which proposes that adaptive processes exist and can moderate relationships between enduring vulnerabilities and different outcomes. Relationships of interest include the negative link between depression and marital satisfaction and the positive link between marital satisfaction and physical health. An adaptive process of interest is empathy, due to its well-researched positive impact on mental, relational, and physical health. This study examined whether perceived spousal empathy (i.e., the empathy perceived by one spouse coming from their spouse) had any moderating effects on the previously mentioned links. …

Improving Perennial Bunchgrass Seeding Success In Annual Grass Invaded Areas Using Pre-Emergent Herbicide And Furrowing Techniques, Spencer Chad Camp

Theses and Dissertations

Exotic annual weeds have transformed western North America, particularly in sagebrush-steppe systems. Restoration of these invaded sites has been met with low levels of success. Pre-emergent herbicide provides a means to control annual weeds, but typically, this treatment does not allow for the concurrent seeding of desired species. Seeding within a deep, U-shaped furrow following herbicide application may be a method to reduce pre-emergent herbicide effects by transferring the herbicide away from the seed at the time of planting. We tested this potential planting technique by spraying plots with or without the pre-emergent herbicide imazapic, and planting bunchgrass seeds either …

Blood Glucose As A Predictor Of Resting Lactate, Hrpr, And Hra As Measured By Method Cra, Sean Pavlick

Theses and Dissertations

Objective: The purpose of this study was to examine fasted blood glucose as a predictor of lactate levels measured by Method CRA. Method: Participants and data for the present study were collected by employees of an orthopedic rehabilitation center in Bloomington, Illinois. Participants recruited for the study followed the Method CRA upright cycle testing protocol. Fasted blood glucose, resting lactate, and heart rate measurements at Prime (2 mmol/L) and Anaerobic (4 mmol/L) were recorded. Blood was sampled every three minutes during exercise testing. The total sample size of 35 was examined as well as two subgroups, BMI > 30 group and …