Digital Commons Network^™

Performance Evaluation Of A Novel Dual-Bed Gasification Reactor For The Production Of Green Energy, Ogooluwa Philip Ojo

Theses and Dissertations

The need to maximize current energy sources and create new ones has increased due to the world's growing energy demand and the depletion of major energy sources. Biomass and solid waste, such as wood, sawdust, plant wastes, paper, cardboard, and plastics, present promising carbon-neutral alternatives, collectively accounting for over 10% of global energy generation. The concept of integrating fixed and fluidized bed reactors in industrial applications needs additional research to ascertain the optimal configuration and interplay between these reactor types. Hence this research focuses on the utilization of a unique hybrid modular gasification system that combines fixed and fluidized bed …

Investigation Of Collision Cross Sections & Time-Resolved Structural Modification Of Biomolecules, Host-Guest Systems, & Small Molecules Using Ion Mobility & Fourier Transform Ion Cyclotron Resonance Mass Spectrometry, Noah Mismash

Theses and Dissertations

This thesis explores the structures and structural changes of supramolecular host-guest systems, proteins, and other small molecules in the gas phase, utilizing a combination of computational modeling and experimental data. The primary instruments employed were a Fourier transform ion cyclotron resonance mass spectrometer (FTICR-MS) and an ion mobility mass spectrometer (IM-MS). In the IM-MS experiments, the focus was on investigating the binding behavior of cyclodextrin macrocycles—specifically α, β, and γ-cyclodextrin—with per-fluoroalkane substances (PFAS), which are pervasive environmental contaminants. This investigation involved measuring ion-neutral collision cross sections and using computational modeling to determine whether PFAS compounds bind inside or outside the …

Discovery Of Oligomeric States And Small Molecules That Affect Deacylase Activities Of Human Sirtuin-2 (Sirt2), Jie Yang

Theses and Dissertations

Human sirtuin isoform 2 (SIRT2) is an NAD+-dependent enzyme that removes various acyl modifications from lysine residues. SIRT2 is involved in many biological processes, such as transcription, DNA repair, cell proliferation, and metabolism. Due to its diverse functions, SIRT2 is implicated in various disease states, including cancers and neurodegenerative disorders. This dissertation aimed to understand the regulation of SIRT2’s deacylase activities and to discover small molecule modulators of SIRT2. In this work, we found that SIRT2 dimerized in solution, and the dimerization decreased the deacetylase activities without affecting the defatty-acylase activity of this protein. Dimerized SIRT2 dissociates into monomers upon …

Mathematical Modeling And Understanding The Physiological Mechanisms Of Vibration On Wound Healing And Scar Remodeling, Devin Rion Needs

Theses and Dissertations

Chronic wounds and pathological scars reduce the quality of life for millions of people worldwide. Through mathematical modeling and clinical testing, understanding of how these conditions occur continues to increase. These tools have also been employed to investigate the efficacy of treatments that could impact wound healing and scar remodeling. The purpose of this work is to investigate the physiological effects of vibration treatment on wound healing, blood flow, and scar remodeling through mathematical modeling and experimental testing. This work presents and validates a mathematical murine model for whole body vibration enhanced wound healing (VEWH). This VEWH model builds on …

Using Rna Sequencing Methodologies To Uncover Common Pathways In Neural Tube Defects: A Comparative Study Of Three Oxidative Neurotoxicants, Aubrey Coleen Johansen

Theses and Dissertations

Neural tube defects (NTDs) are the second most common type of congenital birth defect that affect infants worldwide. There are several proposed mechanisms for NTDs, but no definitive mechanism has yet been described. One possible mechanism is oxidative disruption of normal developmental signaling. The purpose of this study is to culture whole mouse embryos with three common developmental toxicants, mono-2-ethylhexyl phthalate (MEHP, a plastic pollutant), Fumonisin B1 (FB1, a corn mold), and valproic acid (VPA, an anticonvulsant drug), all of which are known to cause NTDs, and compare their shifts in redox potential and changes to important signaling pathways through …

Black Stereotypes In Basketball Films, Carsen Jackson Williams

Theses and Dissertations

This study conducts a frequency analysis on the Black stereotypes portrayed in popular basketball films through the lens of media framing. Academic literature has made a frequent topic of racial bias and its role in professional sports, particularly through sports media. However, there is a gap in the literature when looking specifically at basketball films as a whole and the prevalence therein of racial stereotypes, specifically Black stereotypes. Using framing theory as the backbone of the study, a frequency analysis was completed of main characters in the ten most popular basketball films to identify what Black Stereotypes arise. Most common …

Back To The Future: A Case For The Resurgence Of Approximation Theory For Enabling Data Driven “Intelligence”, Michael Dominic Ciocco

Theses and Dissertations

Artificial Intelligence (AI) has exploded into mainstream consciousness with commercial investments exceeding $90 billion in the last year alone. Inasmuch as consumer-facing applications such ChatGPT offer astounding access to algorithms that were hitherto restricted to academic research labs, public focus of attention on AI has created an avalanche of misinformation. The nexus of investor-driven hype, “surprising” inaccuracies in the answers provided by AI models – now anthropomorphically labeled as “hallucinations”, and impending legislation by well-meaning and concerned governments has resulted in a crisis of confidence in the science of AI. The primary driver for AI’s recent growth is the convergence …

An Examination Of Adverse Childhood Experiences As A Predictor Of Physical Activity In Emerging Adults, Christian Alvarado

Theses and Dissertations

Previous research highlights the impact of adverse childhood experiences (ACEs) on health, yet their association with physical activity (PA) remains underexplored. This study investigated this relationship in a predominantly Hispanic sample of emerging adults, examining whether perceived barriers and benefits to exercise mediate the ACEs-PA relationship. A total of 442 college students aged 18-29 completed all measures. ACEs were assessed using the Adverse Childhood Experiences Questionnaire, PA levels through the International Physical Activity Questionnaire-Short Form (IPAQ-SF), and perceived exercise barriers/benefits via the Exercise Benefits/Barriers Scale. Bootstrapped Pearson correlations indicated a significant negative association between perceived barriers to exercise and PA …

Supporting Latinx Preservice Teachers For Implementing Phenomenon-Based Science To Promote Their Understanding Of The Three Dimensions Of Science Learning With An Emphasis On The Nature Of Science (Nos), Leslie Y. Garrido

Theses and Dissertations

As the adoption rate of the Next Generation Science Standards (NGSS) continues to rise in the United States, there is an increasing need for the development of high-quality instructional materials that reflect NGSS and effectively prepare teachers for its implementation. The NGSS aim to foster an understanding of three interconnected dimensions in students: science and engineering practices (SEP), crosscutting concepts (CCC), and disciplinary core ideas (DCI), along with an understanding of the nature of science (NOS). These standards envision students continuously revising their knowledge through the investigation of real-world phenomena using these dimensions. The State of Texas recently adopted and …

Identifying Barriers To Sustainability Of Dual Language Immersion Programs In Utah Schools, Jennifer Leigh Rowley

Theses and Dissertations

Dual Language Immersion (DLI) educational programming began in Utah in 2008. Within three short years, DLI programs in Utah schools had grown from 5 to 58 programs statewide. Presently, Utah now has over 301 DLI programs, including instruction in Spanish, Chinese, French, Portuguese, Russian, and German. DLI programs have many benefits and have attracted many student families. However, not much research has been done on program planning, implementation, and the sustainability of DLI programs within individual school cultures and climates. This study will examine the satisfaction level of faculty, staff, administrators, and parents at DLI schools (including how supported/understood each …

Exploring The Gap Between Self-Assessed And Actual Language Proficiency: A Comparative Analysis Of Japanese And Romance Language Learners, Megan Scarlet Keys

Theses and Dissertations

This study explores self-assessment accuracy among Japanese second language (L2) learners compared to learners of Romance languages. This research aims to investigate the extent of accuracy in self-assessment among Japanese learners and compare it with their counterparts studying Romance languages. Additionally, the study explores the variables influencing the accuracy of self-assessment in this context. The participants in this study comprised 144 undergraduate students enrolled in Japanese, French, Spanish, or Portuguese courses at Brigham Young University. Most participants possessed practical experience using their L2 in the target cultural context, complementing their academic coursework. The Language Ability Self-Evaluation Resource (LASER) was utilized …

Effect Of Cystic Fibrosis Transmembrane Conductance Regulator (Cftr) Loss In Lung Adenocarcinoma (Luad), Marilyn G. Vallejo Alvarez

Theses and Dissertations

Lung adenocarcinoma (LUAD) is the most common form of non-small cell lung cancer in the United States and is a major cause of cancer-related mortality. Patients with LUAD experience severe pulmonary symptoms and often progress to metastatic disease. Our previous work has shown that LUAD cells downregulate lung cell identity programs across cancer progression such as genes involved in the maintenance of epithelial barrier integrity. For example, CFTR (Cystic Fibrosis Transmembrane Conductance Regulator), a water and bicarbonate channel, is expressed in normal alveolar type 2 (AT2) cells and is downregulated in cells that give rise to LUAD. Although the loss …

Using Rapid Protein Degradation To Determine The Effect Of Runx1 Loss-Of- Function On Dna Damage Accumulation And Repair., Jackriel Pina Morales

Theses and Dissertations

Germline mutations in RUNX1 are associated with familial platelet disorder with a predisposition to myeloid malignancy (RUNX1-FPDMM), in which patients present with low platelet counts,excessive bleeding and bruising, and an increased risk of Acute Myeloid Leukemia (AML)/Myelodysplastic Syndrome (MDS) development throughout their lifetime. To understand how these loss-of-function mutations in RUNX1 drive predispose to malignancy, it is important to develop a detailed understanding of the molecular basis of RUNX1 function. While RUNX1 is a transcription factor, preliminary data from our group and work from others suggests that RUNX1 also interacts with proteins that are critical for DNA damage …

Minimal Specialization: The Coevolution Of Network Structure And Dynamics, Annika King

Theses and Dissertations

The changing topology of a network is driven by the need to maintain or optimize network function. As this function is often related to moving quantities such as traffic, information, etc., efficiently through the network, the structure of the network and the dynamics on the network directly depend on the other. To model this interplay of network structure and dynamics we use the dynamics on the network, or the dynamical processes the network models, to influence the dynamics of the network structure, i.e., to determine where and when to modify the network structure. We model the dynamics on the network …

Design Of Multi-Objective Optimization Algorithms For Vlsi Floor Planning, Srinivasan B

Theses and Dissertations

VLSI floorplanning is a key design step that determines the optimal placement of circuit modules to minimize chip area, wire length, and heat generation. Existing swarm intelligence–based metaheuristics improve area and wire length but often ignore thermal effects.

To address this, the Multi-Objective Firefly Optimization–based Floorplanning (MOFO-FP) technique is introduced, using a Heat-Aware Firefly Optimization (HAFO) algorithm that minimizes heat, space, and wire length under fixed outline constraints. Each firefly represents a floorplan, with brightness indicating solution quality; dimmer fireflies move toward brighter ones to find optimal placements.

A second method, the Hybridized Multicriteria Ant Colony and …

The Impact Of Divided Attention Tasks On Stress: Insights From Heart Rate Variability And Galvanic Skin Response, Kira Stefanie Uluave

Theses and Dissertations

This study examined the impact of divided attention tasks on stress using physiologic measures. The divided attention conditions included speech tasks (conversation or procedural discourse) and non-speech computer-based tasks (visuospatial, mathematical, language, data entry, or text editing). Participants included 60 adults divided into two groups of 30 by age. The young adult group ranged in age from 18-30 years and the older adults ranged from 55-82 years. Participants were required to perform the speech task and the non-speech task in isolation as well as a speech task performed concurrently with each of the non-speech tasks. The order of the tasks …

Dna-Templated Nanofabrication Of Metal-Semiconductor Heterojunctions And Their Electrical Characterization, Chao Pang

Theses and Dissertations

Bottom-up nanofabrication, although still in its early stages with formidable challenges, is considered a potential alternative method to address the limitations of traditional top-down techniques by offering benefits including process simplification, cost reduction, and environmental friendliness. DNA-templated nanofabrication, one of the most powerful bottom-up methods, presents an innovative way to create advanced nanoelectronics. In this approach, nanomaterials with specific electronic, photonic, or other functions are precisely and programmably positioned on DNA nanostructures from a disordered collection of smaller parts. These self-assembled structures offer significant potential for improving many fields such as biosensing, drug delivery and electronic device manufacturing. This dissertation …

The Use Of Music Therapy To Improve Relationships And Increase Bonding And Connectedness Between Adopted Children And Their Adoptive Parents, Hannah Appleyard

Theses and Dissertations

Background: Children who are adopted may face greater difficulty in developing secure attachment with their adoptive parents. Music therapy is one treatment method that could be used to improve relationships between adopted children and their adoptive parents.Purpose: The purpose of this study was to examine the use of music therapy to improve relationships and increase bonding and connectedness between adopted children and their adoptive parents. Four research questions were addressed in this study: (1) How can music therapy improve the relationship between adopted children and their adoptive parents? (2) What is the frequency of behavioral indicators of bonding and connectedness …

Combinatorial Studies Of Noble Metal Catalysts For Carbon Utilization, Natalie Leong Page

Theses and Dissertations

Electrocatalysts demonstrate significant promise for sustainable processes like carbon capture and generating recycled carbon fuels which are needed to achieve net zero carbon emissions. However, the commercialization of these processes is limited by several factors, one of which is the high cost of catalysts. The discovery and development of cheaper alternatives has been difficult due to constraints in experimental methodologies, scalability limitations, and a lack of understanding of reaction mechanisms. Within this dissertation is the development of a novel scanning electrochemical system and its implementation for high-throughput data generation from combinatorially sputtered material libraries. Combinatorial Pd-Au alloys were investigated for …

Design And Development Of Contactless Capacitive Coupled Electrodes For Cardiovascular Signal Acquisition, Ramya Lakshmi Vs

Theses and Dissertations

In biosignal acquisition and physiological monitoring, developing advanced electrode technologies is crucial in enhancing signal quality, minimizing interference, and improving overall reliability. One such innovative approach is the utilization of capacitive-coupled electrodes, a cutting-edge solution that addresses some of the challenges associated with traditional electrodes in biosignal recording.

Capacitive-based sensors have become prominent in physiological signal measurement over the past decade. The electric field from the external affects both the human body and the electrode. The primary aim while designing the capacitive electrode is to maximize the signal-to-noise ratio. Hence, we introduce shielding and guarding techniques to improve the signal-to-noise …

An Exploration Of Power Relations In Select Plays Of Girish Karnad A Foucauldian Perspective, Srinivasa Yogananda Rao Netrakanti

Theses and Dissertations

The present study, ‘An Exploration of Power Relations in Select Plays of Girish Karnad: A Foucauldian Perspective‘ aims to study power relations among the different characters in the three plays of Girish Karnad viz., Tughlaq, Naga-Mandala and Tale- Danda through Foucault's three modalities of power viz., bio-power, disciplinary power and sovereign power.

Chapter 1, Introduction gives a bird-eye view of Foucauldian concepts of power followed by the three modes of objectification and dividing practices, subjects and power relations, inter-connectedness between power and knowledge, panopticism, bio-power and discourses, the application of Foucauldian theories of the three major powers. Next, a Girish …

Design Of An Integrated System For The Protection Of Patient Health Information In Medical Images, Manikandan V

Theses and Dissertations

Electronic clinical data such as Patient Health Information (PHI) is stored by adapting the Digital Imaging and Communications in Medicine (DICOM) standard to build an integrated healthcare system where medical images from various sources can be interlinked. The healthcare industry poses a threat from hackers, and the information fetched by hackers provides more money than the other information stolen. This thesis deals with designing and analysing encryption algorithms, key generation mechanisms, and information-hiding schemes for protecting PHI.

Sensitive multimedia information of all forms is encrypted, with a key, before storage and transmission to protect it from illegal use and manipulation …

Intervening For A Better Social Life? A Comparative Analysis Of Psychological Egoism And Aristotle As Alternate Foundations For Applied Social Psychology's Aims, Samuel D. Major

Theses and Dissertations

The scientific aim which distinguishes applied social psychological research from basic social psychological research is that of using social psychological theory to develop interventions meant to rectify social and practical problems in hopes of fostering a flourishing or thriving social sphere. In developing their interventions, however, many applied social psychologists have failed to consider their pre-investigatory philosophical commitments, commitments which imply the kind of flourishing social life that may come as a result of interventions rooted in them. The aim of this dissertation is to invite applied social psychologists to consider if their frequently noted, yet often unexamined, commitment to …

The "Essence" From Within: A Phenomenological Study Examining The Lived Experiences Of Racial And Ethnic Minoritized Women (Raemw) Senior Level Administrators At 4-Year Predominately White Institutions (Pwis) In The United States (U.S.), Felicia Crockett

Theses and Dissertations

The purpose of this study was to explore the experiences of senior level RAEMW administrators who work at 4-year PWIs in the U.S. and analyze the impact of institutional environments on their success. The theories that guided this study were: Crenshaw’s (1994; 1989; 2015) intersectionality framework and four tenets of CRT which include counter-storytelling, the permanence of racism, interest convergence, and intersectionality (Hiraldo, 2010, 2019). This study was guided by the three research questions: 1) How do RAEMW senior level administrators describe their experiences navigating higher education, 2) How do senior level RAEMW administrators describe the impact of institutional environments …

Intergenerational Transmissions Of Body Image And Eating Issues: An Analysis Of Maternal And Interpersonal Socialization From College-Age Women, Elena Kae Cotter

Theses and Dissertations

Negative body image affects countless young American women and can lead to serious eating concerns if overlooked. A young girl may develop negative body image if she is pressured to fit into dominant social appearance standards perpetuated by the media and social groups such as her friends, peers, and family, especially her mother. One relationship that remains underexplored is that between mothers and daughters, specifically regarding young adult women and their retrospective thoughts on their mothers’ influence on their self-presentation at a young age. This study uses qualitative interviews and content analysis of transcribed interview texts, focusing on maternal influence …

Conservation At The Speed Of Light: Applications Of Non-Invasive Technologies For Assessing Physiological Phenomena In Amphibians, Li-Dunn Chen

Theses and Dissertations

The Anthropocene epoch in which we are currently living, also known as the Holocene, has brought about unprecedented losses in planet Earth’s biodiversity. Numerous extirpations of floral and faunal species have been influenced by human encroachment and more specifically, the exploitation of such species and the respective habitats in which they reside. It is this notion that has propelled many scientists to take up intellectual arms in an effort to protect these invaluable resources. The purpose of this research was to develop technologies to measure and evaluate various variables that influence animal physiology, specifically in amphibians who represent the most …

Physiology And Gut Microbiome Diversity In Honey Bee Colonies Along An Agricultural Intensification Gradient, Urita Mma Agana

Theses and Dissertations

Honeybees (Apis mellifera L.) are the major insect pollinators of many different crops. A drastic decline in the honey bee populations has been reported over the past decade. While many factors have contributed to this decline, pesticides, poor nutrition, and Varroa mites are the most common concerns noted by scientists and beekeepers. Aside from direct toxicity from pesticides, it has been observed that sublethal pesticide doses have effects on honey bee physiology and behavior such as oxidative stress, disruption of foraging and homing, and changes to honey bee neurophysiology. The primary objectives of this project were to examine honey bee …

Abundance And Control Of Nuisance Watershield (Brasenia Schreberi) Populations In Mississippi, Mackenzie M. Lee

Theses and Dissertations

Aquatic nuisance plants (ANS), like watershield (Brasenia schreberi), negatively affect water chemistry, ecosystem ecology, and human uses of waterbodies if not properly managed. Understanding ecological predictors as well as efficient control strategies is needed for successful control of ANS. This research assessed 1) potential environmental and ecological predictors of watershield prevalence along with 2) submersed injections of flumioxazin herbicide for watershield control. Twenty-one lakes in the state of Mississippi were surveyed for watershield presence. Watershield prevalence was not correlated to water clarity or plant diversity suggesting these are not drivers of watershield prevalence. A series of mesocosm and field trials …

“A Hiker Who Is Strong” Is Stronger Than “A Strong Hiker”: Modifier Position Affects Noun Perception, Peter John Weber Ii

Theses and Dissertations

Simple shifts within the syntactic structure of a sentence can have significant effects on the cognitive processes involved in language comprehension (Deckert, 2015; Ellis, 2002; Ferreira, 2003). Modifier position is one such syntactic element that has shown the importance of structure as demonstrated by Karimi et al. (2019). Post-modified words (e.g., a “peasant who was highly educated”) are encoded more robustly and are retrieved more easily than pre-modified words (e.g., a “highly educated peasant”). We explored the potential influence of modifier position on statement believability, namely, how much people believe a statement they have not heard before in Experiment 1. …

Functional Complementation And Occidiofungin Susceptibility Of Fungal Actin Orthologs In S. Cerevisiae, Moshood Fagbolade

Theses and Dissertations

Occidiofungin is an antifungal compound that targets the conserved cytoskeletal protein, actin. Despite >90% amino acid conservation between fungal actin proteins, sensitivity to occidiofungin has been shown to vary with C. albicans, F. oxysporum, and P. digitatum exhibiting a resistant profile relative to S. cerevisiae. To determine whether differences in the amino acid sequences of actin contribute to differences in occidiofungin susceptibility, we expressed the actin gene from these fungal organisms in the ACT1 S. cerevisiae shuffle strain. Functionality of actin gene products was determined by measuring growth kinetics, actin protein levels, nuclear position, and actin cable formation. Results demonstrated …