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Articles 16051 - 16080 of 19641
Full-Text Articles in Entire DC Network
Social Anxiety And The Recognition Of Auditory And Visual Emotional Cues, Ryan D. Hartmann
Social Anxiety And The Recognition Of Auditory And Visual Emotional Cues, Ryan D. Hartmann
Theses and Dissertations
Cognitive theory attributes social anxiety to a host of perceptual biases that transform harmless interpersonal stimuli into threats. Socially anxious college students were expected to misinterpret visual and auditory cues of emotion in others more readily than their more confident counterparts. This group of socially anxious men and women were also expected to perceive negative emotion from visual and auditory cues that were determined to be neutral or positive through an external validation process. A total of 16 participants were assigned into each of the four cells of this 2 (gender) by 2 (Liebowitz Social Anxiety Scale-Self Report median split) …
Bacterial Persistence In Escherichia Coli: Examination Of The Role Of Hipba, Shaleen B. Korch
Bacterial Persistence In Escherichia Coli: Examination Of The Role Of Hipba, Shaleen B. Korch
Theses and Dissertations
Persistence is the ability of a small fraction of bacteria (one-in-a-million) to survive antibiotic exposure, yet the survivors are as susceptible to antibiotic as the parental cells. "High persistence" in Escherichia coli is linked to mutations in hipA, the toxin entity of the toxin-antitoxin module hipBA. The wild type hipA gene encodes a "toxin" while hipB encodes a DNA-binding protein that autoregulates hip operon expression and binds to HipA to nullify its effects. The hipA7 allele confers persistence to 1:100 cells and serves as a model system to study persistence. Wild-type HipA, when in excess of HipB, causes culture growth …
Regulation Of Vascular Smooth Muscle Actin Polymerization: Pathophysiological Implications And Relations To Portal Hypertensive Conditions, Xuesong Chen
Theses and Dissertations
Chronic portal hypertension is an end-state clinical condition associated with cirrhosis and other diseases that elevate portal vascular resistance. An intriguing vascular consequence of chronic portal hypertension is impaired vasoconstrictor function which favors a chronically vasodilated condition. This vasoconstrictor dysfunction has been linked to prolonged activation of protein kinase A (PKA). However the cellular mechanism(s) responsible for the altered vasoconstrictor function is still not clear. The present studies tested my hypothesis that PKA mediates impaired vasoconstrictor function by affecting the actin filament dynamics via two small heat shock proteins, HSP20 and HSP27. Studies were conducted in isolated small mesenteric arteries …
Capillary Electrophoresis Of Proteins With Selective On-Line Affinity Monoliths, Jenny Marcela Armenta Blanco
Capillary Electrophoresis Of Proteins With Selective On-Line Affinity Monoliths, Jenny Marcela Armenta Blanco
Theses and Dissertations
The analysis of proteins in biological fluids by capillary electrophoresis (CE) is of interest in clinical chemistry. However, due to low analyte concentrations and poor concentration limits of detection (CLOD), protein analysis by this technique is frequently challenging. Coupling preconcentration techniques with CE greatly improves the CLOD. An on-line preconcentration-CE method that can selectively preconcentrate any protein for which an antibody is available would be very useful for the analysis of low abundance proteins and would establish CE as a major tool in biomarker discovery. To accomplish this, an on-line protein G monolithic preconcentrator CE system for enrichment and separation …
Learning In Short-Time Horizons With Measurable Costs, Patrick Bowen Mullen
Learning In Short-Time Horizons With Measurable Costs, Patrick Bowen Mullen
Theses and Dissertations
Dynamic pricing is a difficult problem for machine learning. The environment is noisy, dynamic and has a measurable cost associated with exploration that necessitates that learning be done in short-time horizons. These short-time horizons force the learning algorithms to make pricing decisions based on scarce data. In this work, various machine learning algorithms are compared in the context of dynamic pricing. These algorithms include the Kalman filter, artificial neural networks, particle swarm optimization and genetic algorithms. The majority of these algorithms have been modified to handle the pricing problem. The results show that these adaptations allow the learning algorithms to …
Biochemical Investigations Of Macular Degeneration: The Significance Of Protein Oxidation Including Novel Methods For Its Study, Sarah Warburton
Biochemical Investigations Of Macular Degeneration: The Significance Of Protein Oxidation Including Novel Methods For Its Study, Sarah Warburton
Theses and Dissertations
The retinal pigment epithelium (RPE) is a monolayer of cells located directly behind the photoreceptor cells in the retina. These cells are involved in a variety of functions that support the visual process in the eye, namely 1) they form a blood-retina barrier which separates the neural retina from the choroid's blood supply, 2) the apical processes of RPE cells diurnally phagocytose the outer segments of photoreceptor cells, and 3) they participate in the renewal of the photopigment 11-cis retinal. Age-related macular degneration (AMD) is the leading cause of blindness in people over the age of 50 years in North …
Characterization Of Cucurbituril Complex Ions In The Gas Phase Using Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry, Haizhen Zhang
Theses and Dissertations
Host-guest interactions have been well studied in the new century to obtain fundamental insights into supramolecular chemistry. Most of the pioneering works have been done using techniques such as NMR, X-ray crystallography, IR spectroscopy and so on. However, none of these techniques is universal for the investigation of all types of supramolecules, and usually they have one or more limiting factors such as relatively large sample consumption, matrix effects from solvents, etc. Electrospray mass spectrometry has been widely used to investigate host-guest interactions in the gas phase. A particular advantage of gas phase host-guest research is that the experimental results …
Fabrication Of Hollow Optical Waveguides On Planar Substrates, John P. Barber
Fabrication Of Hollow Optical Waveguides On Planar Substrates, John P. Barber
Theses and Dissertations
This dissertation presents the fabrication of hollow optical waveguides integrated on planar substrates. Similar in principle to Bragg waveguides and other photonic crystal waveguides, the antiresonant reflecting optical waveguide (ARROW) is used to guide light in hollow cores filled with liquids or gases. Waveguides with liquid or gas cores are an important new building block for integrated optical sensors. The fabrication method developed for hollow ARROW waveguides makes use of standard microfabrication processes and materials. Dielectric layers are deposited on a silicon wafer using plasma-enhanced chemical vapor deposition (PECVD) to form the bottom layers of the ARROW waveguide. A sacrificial …
Microfabrication And Evaluation Of Planar Thin-Film Microfluidic Devices, Bridget Ann Peeni
Microfabrication And Evaluation Of Planar Thin-Film Microfluidic Devices, Bridget Ann Peeni
Theses and Dissertations
Over the past 15 years, research in the field of microfluidics has rapidly gained popularity. By seeking to miniaturize and automate separation-based analysis, microfluidic research seeks to improve current methods through decreased cost, analysis time, and sources of contamination. My work has focused on developing a novel fabrication method, based on standard microfabrication techniques, to create thin-film microfluidic devices. This microfabrication format makes it possible to generate devices that provide high efficiencies, enable mass fabrication, and provide a platform capable of integrating the microfluidic and electronic components necessary for a micro-total analysis system (μ-TAS). Device fabrication combines the processes of …
Determining Multiple Intelligences In The Preschool Aged Child, Jill Elizabeth Capie
Determining Multiple Intelligences In The Preschool Aged Child, Jill Elizabeth Capie
Theses and Dissertations
The objective of this research study was to explore whether valid Multiple Intelligence profiles could be created for preschool children. This study was conducted over a three month period and included 16 preschool-aged participants. Research strategies included surveys (teacher, paraprofessional, and parent), naturalistic observations, and participant interviews. There were four key findings in this study. First, the teacher, the paraprofessional, and the parents had differing perceptions about which intelligences were dominant for each participant. Second, participants appear to have multiple, equally dominant intelligences. Third, participant's views related to their own dominant intelligences frequently differed from those reported by the teacher, …
Studies On Cyclooxygenase-1, Its Structure And Splice Variants, And Modulation Of Cyclooxygenase-2 By Inducible Nitric Oxide Synthase And Novel Phytochemicals., Yibing Xu
Theses and Dissertations
Cyclooxygenases (COXs) are of important therapeutic value as they are the target site of aspirin-like drugs. Here I report nine new COX-1 splice variants in chapter 1, which I characterized with regard to heme-binding and other properties. Inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2) are co-inducible in many tissues following mitogenic and proinflammatory stimulation. In chapter 2, I investigate the physical and enzymatic properties of human COX-2 and iNOS and demonstrate that, despite reports to the contrary by another laboratory, they do not interact. The only reported COX-1 splice variant to exhibit cyclooxygenase activity has been isolated from …
Design Of Piezoresistive Mems Force And Displacement Sensors, Tyler Lane Waterfall
Design Of Piezoresistive Mems Force And Displacement Sensors, Tyler Lane Waterfall
Theses and Dissertations
MEMS (MicroElectroMechanical Systems) sensors are used in acceleration, flow, pressure and force sensing applications on the micro and macro levels. Much research has focused on improving sensor precision, range, reliability, and ease of manufacture and operation. One exciting possibility for improving the capability of micro sensors lies in exploiting the piezoresistive properties of silicon, the material of choice in many MEMS fabrication processes. Piezoresistivity—the change of electrical resistance due to an applied strain—is a valuable material property of silicon due to its potential for high signal output and on-chip and feedback-control possibilities. However, successful design of piezoresistive micro sensors requires …
Detection Of Proteins By Two-Photon Excitation Of Native Fluorescence, Li Li
Detection Of Proteins By Two-Photon Excitation Of Native Fluorescence, Li Li
Theses and Dissertations
Proteins are of primary importance to the structure and function of all living cells. Study of proteins relies on the ability to separate a complex mixture so that individual proteins can be more easily processed by other techniques. Since protein samples often exist at low concentration in a small volume, the trend in chemical analysis is toward micro total analysis systems (µTAS) or lab-on-a-chip devices. Among µTAS separation methods, the relatively new electric field gradient focusing (EFGF) technique has shown potential. It focuses and separates analytes based on their electrophoretic migration in an opposing hydrodynamic flow. The detection principles that …
Experimental And Modeling Investigations Of Biomass Particle Combustion, Hong Lu
Experimental And Modeling Investigations Of Biomass Particle Combustion, Hong Lu
Theses and Dissertations
This investigation provides a comprehensive analysis of entrained-flow biomass combustion processes. Experimental and theoretical investigations indicate how particle shape and size influence biomass combustion rates. Experimental samples include flake-like, cylinder-like, and equant (nearly spherical) shapes with similar particle masses and volumes but different surface areas. Samples of small (less than 500 µm) particles were passed through a laboratory entrained-flow reactor in a nitrogen/air atmosphere and a maximum reactor wall temperature of 1600 K, while large samples were reacted in suspension in a single particle furnace operated at similar conditions as the entrained-flow reactor. A separately developed computer and image analysis …
Construction Of A Col11a1 Transgene Vector, Cameron Mckell Beck
Construction Of A Col11a1 Transgene Vector, Cameron Mckell Beck
Theses and Dissertations
Background: Cartilage disorders affect millions of people in the United States alone, with effects ranging from poor skeletal development and joint pain to shortened lifespan and perinatal lethality. Many of these disorders have their root in defects of collagen, type XI collagen being among the most important. A mouse model of such a type XI collagen defect is the chondrodysplasia (cho) mutant. Mice homozygous for this null mutation in the Col11a1 gene do not express the α1 chain of type XI collagen. This results in a functional knockout of type XI collagen, leading to insufficient skeletal development and perinatal lethality. …
Sources Of Variability In A Proteomic Experiment, Scott Daniel Crawford
Sources Of Variability In A Proteomic Experiment, Scott Daniel Crawford
Theses and Dissertations
The study of proteomics holds the hope for detecting serious diseases earlier than is currently possible by analyzing blood samples in a mass spectrometer. Unfortunately, the statistics involved in comparing a control group to a diseased group are not trivial, and these difficulties have led others to incorrect decisions in the past. This paper considers a nested design that was used to quantify and identify the sources of variation in the mass spectrometer at BYU, so that correct conclusions can be drawn from blood samples analyzed in proteomics. Algorithms were developed which detect, align, correct, and cluster the peaks in …
Ferritin: Mechanistic Studies And Electron Transfer Properties, Bo Zhang
Ferritin: Mechanistic Studies And Electron Transfer Properties, Bo Zhang
Theses and Dissertations
Ferritins are ubiquitous iron storage proteins in living systems. Although much is known about the iron deposition process in ferritin and a mechanism has been developed, several important issues still remain unknown. One lingering question is the less than stoichiometric quantities of hydrogen peroxide detected in previous studies on animal ferritins. Extensive experimental data on identifying the species in competition for peroxide equivalents point to a surprising conclusion that H2O2 generated in the ferroxidase reaction is consumed by amine buffers that are commonly employed in in vitro ferritin studies, while non-nitrogen containing buffers, such as acetate, phosphate, and carbonate, do …
The Phylogeography Of Prosopium In Western North America, Becky Akiko Miller
The Phylogeography Of Prosopium In Western North America, Becky Akiko Miller
Theses and Dissertations
The mountain whitefish (Prosopium williamsoni) has been largely overlooked in population genetic analyses despite its wide distribution in discrete drainage basins in western North America for over four million years. Its closest sister taxa the Bear Lake whitefish (P. abyssicola), Bonneville cisco (P. gemmifer), and Bonneville whitefish (P. spilonotus) are found only in Bear Lake Idaho-Utah and were also included in the analyses. A total of 1,334 cytochrome b and 1,371 NADH dehydrogenase subunit 2 sequences from the Bonneville Basin, the Columbia River Sub-basin, the lower Snake River Sub-basin, the upper Snake River Sub-basin, the Green River Basin, the Lahontan …
Computational Simulation Of Dynamics Of Nematic Liquid Crystals In The Presence Of Nanoparticles And Biological Macromolecules, Huangli Wu
Theses and Dissertations
Recent research shows that liquid crystals can be used to report the presence of different types of substances through optical amplication of ligand-receptor binding. In this work, simulations based on a coarse-grained method have been performed to study a class of liquid-crystal-based sensors. A tensor order parameter was used to model the liquid crystalline system and the Beris-Edwards formulation was employed to obtain the time evolution of a liquid crystal medium containing particles. The simulation cases are built using three-dimensional unstructured meshes and the simulation geometries studied include simple models involving spheres as well as detailed modeling for a protein. …
Conservation And Management Of Paddlefish In Mississippi With Emphasis On The Tennessee-Tombigbee Waterway, Daniel Mark O'Keefe
Conservation And Management Of Paddlefish In Mississippi With Emphasis On The Tennessee-Tombigbee Waterway, Daniel Mark O'Keefe
Theses and Dissertations
Paddlefish are long-lived large river fish which are declining in many areas of their range due to habitat modifications and overfishing. A framework for management of paddlefish in Mississippi is proposed and a case study of its application to the paddlefish population of the Tennessee-Tombigbee Waterway (TTW) is presented. The framework includes four phases: (I) distribution and stock assessment; (II) determination of limiting factors; (III) design and implementation of management actions; and (IV) review and monitoring. Phase I of management in the TTW consisted of gill-net surveys in four impoundments. Paddlefish abundance was estimated at 1,581 to 8,851 in Demopolis …
Development Of A Proof-Of-Concept Backpackable Unmanned Aerial Vehicle, Calvin Russell Walker
Development Of A Proof-Of-Concept Backpackable Unmanned Aerial Vehicle, Calvin Russell Walker
Theses and Dissertations
This thesis documents the design and development of a robust backpackable proof-of-concept unmanned aerial vehicle. The unmanned aerial vehicle?s design departs from existing configurations in utilizing a keel beam fuselage which replaces the enclosed fuselage by a flat keel beam on which the sensors, the autopilot, their related power sources, and flight control systems are mounted. The keel beam fuselage is provides enhanced mounting capability for multiple sensors and quick reconfiguration in the field. The keel beam fuselage can also be manufactured quicker than a traditional enclosed fuselage. The objective of this study is to demonstrate that the keel beam …
Can Holistic Wellness Predict Teacher Effectiveness?, Dana Rolison Harwell
Can Holistic Wellness Predict Teacher Effectiveness?, Dana Rolison Harwell
Theses and Dissertations
Wellness literature reported that the current focus on academic achievement and high-stakes testing has sacrificed wellness in students, and ?there is a strong need and a public outcry to promote wellness in public schools? (Myers & Sweeney, 2005a, p. 228). Also, ?the promotion of schoolwide well-being will enrich the academic experience of students and families. In addition, school staff members who are aware and knowledgeable of wellness concepts may be more likely to apply healthy strategies in the curriculum and throughout the school? (Myers & Sweeney, p. 232). Effective teacher research supported the Student Teacher Assessment Instrument as a viable …
An Archaeological Investigation Of Four Woodland-Period Sites In The North Central Hills Physiographic Region Of Mississippi, Jason Lee Parrish
An Archaeological Investigation Of Four Woodland-Period Sites In The North Central Hills Physiographic Region Of Mississippi, Jason Lee Parrish
Theses and Dissertations
Woodland-period archaeological sites in the North Central Hills physiographic region of Mississippi appear to be highly variable in occupation size, site function, duration, and occupational intensity. To better understand the occupational history and settlement patterns of such sites, several characteristics of four Woodland-period sites located within the Tombigbee National Forest, Ackerman Unit, Mississippi, are evaluated and compared to a larger, previously investigated site, 22WI516. From the data obtained in the field and laboratory, a determination of the causes of the variability among Woodland-period sites in the study area is attempted. Physiographic constraints appear to underlie much of the variability presented …
Mechanobiology Of Soft Tissue Differentiation: Effect Of Hydrostatic Pressure, Joon Wan Shim
Mechanobiology Of Soft Tissue Differentiation: Effect Of Hydrostatic Pressure, Joon Wan Shim
Theses and Dissertations
This study was motivated by a theoretical formulation on mechanobiology of soft and hard skeletal tissue differentiation. To prove this formulation experimentally, I hypothesized that cartilaginous phenotype can be induced in vitro in a seemingly non-cartilaginous cell source from fibrous tissue. In testing this hypothesis, I have focused on cartilage as a target and fibrous tissue as an origin or the source of cell. Four different trials were pursued with one supposition in common, i.e. hydrostatic pressure is one of the main driving forces for chondroinduction in vitro. The first and second trials pertained to the influence of a relatively …
Finite Element-Boundary Integral Method And Its Application To Implantable Antenna Design For Wireless Data Telemetry, Jose S. Pvillalta
Finite Element-Boundary Integral Method And Its Application To Implantable Antenna Design For Wireless Data Telemetry, Jose S. Pvillalta
Theses and Dissertations
A non-stationary Krylov subspace based iterative solver for the three dimensional finite element-boundary integral (FE-BI) method for implantable antennas is presented. The present method numerically solves the frequency domain Maxwell?s equations in the variational form to formulate the finite element solution using hexahedral discretization elements in conjunction with the appropriate boundary integral equations. Four different solvers are used to investigate the convergence behavior of the FE-BI technique on the design of the antennas. The scheme is then applied to two miniaturized planar inverted-F antennas (PIFA): a serpentine and a spiral. The antennas are designed for the Medical Implant Communication Service …
Statistical Analysis Of The Effects Of Atropine And Propranolol On The Inter-Beat Interval Of Rats, Abdud Dahian
Statistical Analysis Of The Effects Of Atropine And Propranolol On The Inter-Beat Interval Of Rats, Abdud Dahian
Theses and Dissertations
Heart rate variability (HRV) analysis has proved to be an important tool for assessing autonomic nervous system. For instance, it has been used during dipyridamole echocardiographic test to differentiate ischemic from nonischemic responses [6]. RR Interval analysis can provide additional information that can lead to early detection of a possible change in the activity of the autonomic nervous system. HRV analysis can be done using Wavelet Transform. This thesis presents a modification of an existing algorithm for extracting the R-R interval from EKG data sets and the use of wavelet transform (WT) technique to compute the timerequency domain energy quantities. …
Nlcviz: Tensor Visualization And Defect Detection In Nematic Liquid Crystals, Ketan Mehta
Nlcviz: Tensor Visualization And Defect Detection In Nematic Liquid Crystals, Ketan Mehta
Theses and Dissertations
Visualization and exploration of nematic liquid crystal (NLC) data is a challenging task due to the multidimensional and multivariate nature of the data. Simulation study of an NLC consists of multiple timesteps, where each timestep computes scalar, vector, and tensor parameters on a geometrical mesh. Scientists developing an understanding of liquid crystal interaction and physics require tools and techniques for effective exploration, visualization, and analysis of these data sets. Traditionally, scientists have used a combination of different tools and techniques like 2D plots, histograms, cut views, etc. for data visualization and analysis. However, such an environment does not provide the …
Adsorption Of Water Contaminants Onto Kenaf Fibers, Stephen Douglas Tolar
Adsorption Of Water Contaminants Onto Kenaf Fibers, Stephen Douglas Tolar
Theses and Dissertations
In this research, the adsorptive capacities of kenaf in the forms of chopped whole stalk, chopped core, and bast materials were evaluated for the removal of lead, zinc, and toluene from contaminated synthetic waste streams using traditional adsorption isotherm techniques. The effect of surface oxidation using ozone was observed with respect to the adsorption of metals. Hydraulic conductivity experiments were conducted to evaluate the head loss associated with packing a column with kenaf fibers and to determine the suitability of its use in dynamic packed column systems. B.E.T. surface areas were determined as well. Under increasingly stringent regulatory requirements, even …
Applying Goodness-Of-Fit Techniques In Testing Time Series Gaussianity And Linearity, Nusrat Jahan
Applying Goodness-Of-Fit Techniques In Testing Time Series Gaussianity And Linearity, Nusrat Jahan
Theses and Dissertations
In this study, we present two new frequency domain tests for testing the Gaussianity and linearity of a sixth-order stationary univariate time series. Both are two-stage tests. The first stage is a test for the Gaussianity of the series. Under Gaussianity, the estimated normalized bispectrum has an asymptotic chi-square distribution with two degrees of freedom. If Gaussianity is rejected, the test proceeds to the second stage, which tests for linearity. Under linearity, with non-Gaussian errors, the estimated normalized bispectrum has an asymptotic non-central chi-square distribution with two degrees of freedom and constant noncentrality parameter. If the process is nonlinear, the …
Utilization Of Deionized Water And Non-Meat Adjuncts To Combat Quality Issues In Boneless Cured Ham Associated With Using Pale Raw Material, Jonathan Wilbourn
Utilization Of Deionized Water And Non-Meat Adjuncts To Combat Quality Issues In Boneless Cured Ham Associated With Using Pale Raw Material, Jonathan Wilbourn
Theses and Dissertations
The effects of deionized water and PSE pork percentage on the quality of smoked deli ham and retorted pouched ham with and without non-meat adjuncts were evaluated. Product quality was determined through evaluation of water holding capacity, cooked color, protein-protein bind, and sensory quality. A randomized complete block design with either three or four replications was utilized to test treatment effects in three separate experiments. The retorting process showed the potential to reduce the effect of PSE meat on color that is present in raw material and smoked deli ham. In retorted ham, modified food starch and soy protein concentrate …