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Articles 14011 - 14040 of 19641
Full-Text Articles in Entire DC Network
The Effects Of Acute And Chronic Nicotine On Gaba And Dopamine Neurons In The Midbrain Ventral Tegmental Area, Devin Hardy Taylor
The Effects Of Acute And Chronic Nicotine On Gaba And Dopamine Neurons In The Midbrain Ventral Tegmental Area, Devin Hardy Taylor
Theses and Dissertations
Nicotine (NIC) abuse involves activation of midbrain dopamine (DA) neurons and NIC addiction involves neuroadaptive changes in the mesolimbic DA reward system. GABA neurons in the midbrain ventral tegmental area (VTA) express α4β2-containing nicotinic acetylcholine receptors (nAChRs), whose activation increases GABAergic input to DA neurons. However, this initial effect is decreased after chronic NIC treatment (as in the case of smokers) by inducing nAChR desensitization. Thus, GABA neuron inhibition results in increased DA release in limbic structures such as the nucleus accumbens. To support this hypothesis, we evaluated the effects of acute and chronic NIC on GAD-67 positive neurons in …
Super Collision Energy Transfer Studies In Single Collisions Between Vibrationally Hot Benzene Like Molecules And Ground State Bath Molecules: The Effect Of Physical Properties Of Donor And Bath Molecules On Super Collision Energy Transfer, Kilyoung Kim
Theses and Dissertations
This research is focused on single-collision energy transfer events between highly vibrationally excited benzene-like donor molecules and small bath molecules, CO2 and N2O in the vibrational ground level. Measuring how much energy is transferred from donors to bath molecules was accomplished by probing bath molecules scattered into specific-rotational states using a tunable Δv=0.0003 cm-1 solid state diode laser. The normalized energy transfer probability distribution function, P(E,E'), determined from energy gain information, is very useful in comparing collisional energy transfer efficiency between various collision systems. P(E,E') is also used to investigate the effects of donor and bath physical properties on collisional …
Characterization And In Vitro Toxicity Of Copper Nanoparticles (Cu-Nps) In Murine Neuroblastoma (N2a) Cells, Sitao Veronica Brownheim
Characterization And In Vitro Toxicity Of Copper Nanoparticles (Cu-Nps) In Murine Neuroblastoma (N2a) Cells, Sitao Veronica Brownheim
Theses and Dissertations
Nanomaterials, classified as materials within the 1 - 100 nanometer range, have seemingly endless applications. It is very important to the Air Force to increase the understanding of Cu-NPs and the possible health impacts from nanomaterial exposure prior to wide-spread industry and military use. Therefore, the purpose of this research is to thoroughly characterize the properties of three different copper samples upon suspension into aqueous solutions over time: Cu-NPs (Cu 25 nm), CuO-NPs (CuO 40 nm), and Cu-MSP (Cu 500nm). Additionally, this research seeks to observe in vitro effects upon murine neuroblastoma cells (N2A) by these three types of particles …
Multiple Integrated Navigation Sensors For Improving Occupancy Grid Fastslam, Christopher P. Weyers
Multiple Integrated Navigation Sensors For Improving Occupancy Grid Fastslam, Christopher P. Weyers
Theses and Dissertations
An autonomous vehicle must accurately observe its location within the environment to interact with objects and accomplish its mission. When its environment is unknown, the vehicle must construct a map detailing its surroundings while using it to maintain an accurate location. Such a vehicle is faced with the circularly defined Simultaneous Localization and Mapping (SLAM) problem. However difficult, SLAM is a critical component of autonomous vehicle exploration with applications to search and rescue. To current knowledge, this research presents the first SLAM solution to integrate stereo cameras, inertial measurements, and vehicle odometry into a Multiple Integrated Navigation Sensor (MINS) path. …
A Comparison In The Accuracy Of Mapping Nuclear Fallout Patterns Using Hpac, Hysplit, Delfic Fpt And An Afit Fortran95 Fallout Deposition Code, April D. Miller
A Comparison In The Accuracy Of Mapping Nuclear Fallout Patterns Using Hpac, Hysplit, Delfic Fpt And An Afit Fortran95 Fallout Deposition Code, April D. Miller
Theses and Dissertations
Four nuclear fallout mapping tools are studied to determine which tool predicts the most accurate fallout dose-rate contours with low computation time and resources. The four programs consist of the FORTRAN95 based Fallout Deposition Code (FDC), the Hazard Prediction and Assessment Capability's (HPAC) Nuclear Weapon (NWPN), the Defense Land Fallout Interpretative Code (DELFIC) Fallout Planning Tool (FPT) and the Hybrid Single-Particle Lagrangian Integrated Trajectory (HYSPLIT) Model. The models were compared to the Defense Nuclear Agency's (DNA) DNA 1251-1-EX, Compilation of Local Fallout Data from Test Detonations 1945-1962 Extracted from DASA 1251, using Warner and Platt's Measure of Effectiveness (MOE) method. …
An Analytical Model Of Nanometer Scale Viscoelastic Properties Of Polymer Surfaces Measured Using An Atomic Force Microscope, Jacob B. Goldberg
An Analytical Model Of Nanometer Scale Viscoelastic Properties Of Polymer Surfaces Measured Using An Atomic Force Microscope, Jacob B. Goldberg
Theses and Dissertations
The United States Air Force and the Department of Defense is increasingly interested in nanomaterials. To study these materials, one needs to measure the mechanics of materials on the nanoscale. Over the past few decades the atomic force microscope (AFM) has been used in various methods to establish local surface properties at the nanoscale. In particular, surface elasticity measurements are crucial to understanding nanoscale surface properties. Problems arise, however, when measuring soft surfaces such as polymers and biological specimens, because these materials have a more complex viscoelastic response. This research focuses on modeling an AFM dynamic nanoindentation experiment intended to …
Modeling Of Bacillus Spores: Inactivation And Outgrowth, Alexis X. Hurst
Modeling Of Bacillus Spores: Inactivation And Outgrowth, Alexis X. Hurst
Theses and Dissertations
This research models and analyzes the thermochemical damage produced in Bacillus spores by short, high-temperature exposures as well the repair process within damaged Bacillus spores. Thermochemical damage in spores is significantly due to reaction with water, hydrolysis reactions. Applying heat to the spore causes absorbed and chemically bound water molecules become mobile within the spore. These mobile water molecules react by hydrolysis reactions to degrade DNA and enzyme molecules in the spore. In order to survive the thermal inactivation, the spore must repair the damaged DNA during spore germination. The DNA repair process, as well as other germination functions, is …
Nuclear Enterprise Performance Measurement, Andrew S. Hackleman
Nuclear Enterprise Performance Measurement, Andrew S. Hackleman
Theses and Dissertations
The criticality of the United States Air Force nuclear enterprise demands that commanders have the best possible understanding of system performance, both in the aggregate and at the drill-down levels sufficient to make timely corrective actions when warranted. We model a strategy-linked measurement system for nuclear enterprise sustainment. We propose a new Aggregation "h" method for aggregating performance metrics using United States Air Force approved or adapted metrics that possess the capability to weight metrics, as well as compare performance between organizations and within the same organization over time. We demonstrate our method with generated performance data designed to test …
Migration Issues In The Democratic Republic Of Congo, Michael J. Thompson
Migration Issues In The Democratic Republic Of Congo, Michael J. Thompson
Theses and Dissertations
Since the end of the Cold War, the number of weak and failing states has increased significantly. The United States (US) military has been deployed in multiple nation states in an effort to prevent these weak states from collapsing into chaos. This thesis explores one of the driving factors of state collapse, net migration, to gauge how US foreign policy might be employed to reduce the flow of people out of a country. To demonstrate the foreign policies and their effects, a pilot model was constructed using a system dynamics methodology. The Democratic Republic of Congo (DRC) was selected as …
Evaluation Of Xmx/2l-Mil Virtual Impactor Performance And Capture And Retention Of Aerosol Particles In Two Different Collection Media, Jon E. Black
Theses and Dissertations
The United States Air Force uses the XMX/2L-MIL (XMX) high volume air sampler to collect samples for biological analysis. The XMX uses a virtual impactor to concentrate particles 1.0 to 10 μm in size into a secondary flow prior to sample collection using a liquid impinger in a collection tube. There are no known published studies regarding virtual impactor inter-instrument variability, effect of reducing the secondary flow on particle concentration, or capture and retention efficiency (CRE) of particles in the collection media performance characteristics when using the XMX. These performance characteristics were evaluated by lofting test aerosols of Arizona Road …
A Study Of Corporate Entrepreneurship In A Department Of Defense Organization, Wade W. Brower
A Study Of Corporate Entrepreneurship In A Department Of Defense Organization, Wade W. Brower
Theses and Dissertations
What determines if an organization has a corporate entrepreneurship (CE) environment? While being entrepreneurial in a private sector job usually means a greater market share or a higher profit margin; in a public research organization, CE must be measured in other ways. This thesis evaluates a Department of Defense (DoD) organization that performs basic research. Any organization that does government or nonprofit work must continually find new ways, methods, processes, or ideas to complete the mission. In this particular study, the mission is to continue to support the warfighter with limited and changing resources—to ensure the military can maintain dominance …
Development Of Optimized Guidelines For Therapeutic Strategies For Organophosphate Poisoning, Craig A. Holder
Development Of Optimized Guidelines For Therapeutic Strategies For Organophosphate Poisoning, Craig A. Holder
Theses and Dissertations
Organophosphates such as nerve agents have been used on several occasions in the past to inflict harm upon military and civilian populations in various parts of the world. The threat of these chemicals use against the military and civilians continues today, and the suggested treatment guidelines available may be ineffective or possibly cause harm. The guidelines investigated during the research presented here all included the use of two antidotes, atropine and oxime. The efficacy of oximes has been questioned and it has been suggested that they may cause harm to the patient. Both atropine and oxime are issued to military …
Composite Aircraft Life Cycle Cost Estimating Model, Daniel B. Lambert
Composite Aircraft Life Cycle Cost Estimating Model, Daniel B. Lambert
Theses and Dissertations
Composite materials are beginning to comprise a greater percentage of structural materials used throughout aircraft production. The increased usage of composites has led individuals within the Air Force community to revisit aircraft life cycle cost, LCC, models. A series of affordability initiatives has culminated in significant evidence over the last decade to better quantify the impact of primarily composite structures in aircraft. The Advanced Composite Cargo Aircraft, ACCA, a research effort sponsored by the Air Force Research Lab, attempted to determine the impact of part size and large scale composite components on LCC for cargo aircraft. This research evaluates the …
Modeling Enhanced Storage Of Groundwater Contaminants Due To The Presence Of Cracks In Low Permeability Zones Underlying Contaminant Source Areas, Jeremy M. Miniter
Modeling Enhanced Storage Of Groundwater Contaminants Due To The Presence Of Cracks In Low Permeability Zones Underlying Contaminant Source Areas, Jeremy M. Miniter
Theses and Dissertations
Throughout DoD, chlorinated aliphatic hydrocarbons (CAHs), a type of Dense Non-Aqueous Phase Liquid (DNAPL), have been frequently used. In the subsurface, spilled DNAPLs may pool atop low permeability clay layers. In this study a numerical model is constructed using the Groundwater Modeling System to assess how cracks in the clay, either pre-existing or the result of DNAPL-clay interactions, might impact a dissolved CAH plume generated by the DNAPL source. The conceptual model posits a DNAPL source in a high permeability sand aquifer sitting atop a low permeability clay layer. The model assumes dissolved CAH generated by the DNAPL is transported …
Modeling Vertical Flow Treatment Wetland Hydraulics To Optimize Treatment Efficiency, David T. Roen Ii
Modeling Vertical Flow Treatment Wetland Hydraulics To Optimize Treatment Efficiency, David T. Roen Ii
Theses and Dissertations
An upward Vertical Flow Treatment Wetland (uVFTW) at Wright Patterson AFB designed to bioremediate contaminated groundwater exhibits hydraulic short-circuiting. Prior studies estimated that groundwater flowed through less than 50% of the wetland’s volume, and that the mean residence time was significantly less than the nominal residence time, which was calculated assuming flow through the entire wetland volume. The objective of this research was to investigate how uVFTW hydraulics affects treatment efficiency, and to propose design strategies to maximize treatment efficiency. A groundwater flow and contaminant transport model of a uVFTW that couples hydraulics and degradation kinetics was built and applied …
Characterization Of Graphite Composite Material Particulates From Usaf Aircraft Maintenance Operations, Richard E. Yon
Characterization Of Graphite Composite Material Particulates From Usaf Aircraft Maintenance Operations, Richard E. Yon
Theses and Dissertations
Due to the benefits of their material properties, advanced composite materials (ACM) are increasingly being used as structural components on aircraft, especially within the United States Air Force. As a result, the potential exists for occupational exposures to structural maintenance employees while repairing and fabricating aircraft components. Two field studies were conducted for this thesis in order to characterize ACM aerosol size distribution, determine the feasibility of utilizing direct reading instruments (DRIs) in the field, and ensure workers are protected with adequate controls. In order to characterize exposure, traditional integrated air sampling and DRIs were positioned together near an ACM …
Repeatable Manufacture Of Wings For Flapping Wing Micro Air Vehicles Using Microelectromechanical System (Mems) Fabrication Techniques, David S. Dawson
Repeatable Manufacture Of Wings For Flapping Wing Micro Air Vehicles Using Microelectromechanical System (Mems) Fabrication Techniques, David S. Dawson
Theses and Dissertations
While there have been great advances in the area of Flapping Wing Micro Air Vehicles (FWMAV), prototype parts have been constructed with the objective of scientific discovery and basic research. There has been little effort to make parts that could be consistently and repeatedly manufactured. Until recently, there has been little, if any, focus on methods that could be used and verified by subsequent researchers. It is herein proposed that Microelectromechanical System fabrication methods will provide a fast, cheap, and highly repeatable manufacturing method for the FWMAV wings. The wings manufactured to demonstrate this process, bio-inspired by the Manduca Sexta, …
Manufacturing And Evaluation Of A Biologically Inspired Engineered Mav Wing Compared To The Manduca Sexta Wing Under Simulated Flapping Conditions, Nathanial E. Deleon
Manufacturing And Evaluation Of A Biologically Inspired Engineered Mav Wing Compared To The Manduca Sexta Wing Under Simulated Flapping Conditions, Nathanial E. Deleon
Theses and Dissertations
In recent years, researchers have expressed a vested interest in the concepts surrounding flapping wing micro air vehicles (FWMAVs) that are capable of both range and complex maneuvering. Most research in this arena has found itself concentrated on topics such as flapping dynamics and the associated fluid-structure interactions inherent in the motion, however there still remains myriad questions concerning the structural qualities intrinsic to the wings themselves. Using nature as the template for design, FWMAV wings were constructed using carbon fiber and Kapton and tested under simplified flapping conditions by analyzing frozen' digital images of the deformed wing by methods …
Small Internal Combustion Engine Testing For A Hybrid-Electric Remotely-Piloted Aircraft, Isseyas H. Mengistu
Small Internal Combustion Engine Testing For A Hybrid-Electric Remotely-Piloted Aircraft, Isseyas H. Mengistu
Theses and Dissertations
Efficient operation of a hybrid-electric propulsion system (HEPS) powering a small remotely-piloted aircraft (RPA) requires that a controller have accurate and detailed engine and electric motor performance data. Many small internal combustion engines (ICEs) currently used on various small RPA were designed for use by the recreational hobbyist radio-control (R/C) aircraft market. Often, the manufacturers of these engines do not make accurate and reliable detailed engine performance data available for their engines. A dynamometer testing stand was assembled to test various small ICEs. These engines were tested with automotive unleaded gasoline (the manufacturer's recommended fuel) using the dynamometer setup. Torque, …
Overcoming Pose Limitations Of A Skin-Cued Histograms Of Oriented Gradients Dismount Detector Through Contextual Use Of Skin Islands And Multiple Support Vector Machines, Jonathon R. Climer
Overcoming Pose Limitations Of A Skin-Cued Histograms Of Oriented Gradients Dismount Detector Through Contextual Use Of Skin Islands And Multiple Support Vector Machines, Jonathon R. Climer
Theses and Dissertations
This thesis provides a novel visualization method to analyze the impact that articulations in dismount pose and camera aspect angle have on histograms of oriented gradients (HOG) features and eventual detections. Insights from these relationships are used to identify limitations in a state of the art skin cued HOG dismount detector's ability to detect poses not in a standard upright stances. Improvements to detector performance are made by further leveraging available skin information, reducing false detections by an additional order of magnitude. In addition, a method is outlined for training supplemental support vector machines (SVMs) from computer generated data, for …
A Multi Agent System For Flow-Based Intrusion Detection Using Reputation And Evolutionary Computation, David Hancock
A Multi Agent System For Flow-Based Intrusion Detection Using Reputation And Evolutionary Computation, David Hancock
Theses and Dissertations
The rising sophistication of cyber threats as well as the improvement of physical computer network properties present increasing challenges to contemporary Intrusion Detection (ID) techniques. To respond to these challenges, a multi agent system (MAS) coupled with flow-based ID techniques may effectively complement traditional ID systems. This paper develops: 1) a scalable software architecture for a new, self-organized, multi agent, flow-based ID system; and 2) a network simulation environment suitable for evaluating implementations of this MAS architecture and for other research purposes. Self-organization is achieved via 1) a reputation system that influences agent mobility in the search for effective vantage …
Sawdust Pyrolysis And Petroleum Coke Co2 Gasification At High Heating Rates, Aaron D. Lewis
Sawdust Pyrolysis And Petroleum Coke Co2 Gasification At High Heating Rates, Aaron D. Lewis
Theses and Dissertations
Clean and efficient electricity can be generated using an Integrated Gasification Combined Cycle (IGCC). Although IGCC is typically used with coal, it can also be used to gasify other carbonaceous species like biomass and petroleum coke. It is important to understand the pyrolysis and gasification of these species in order to design commercial gasifiers and also to determine optimal conditions for operation. High heating-rate (100,000 K/s) pyrolysis experiments were performed with biomass (sawdust) in BYU's atmospheric flat-flame burner reactor at conditions ranging from 1163 to 1433 K with particle residence times ranging from 23 to 102 ms. Volatile yields and …
Role Of Wnt5a And Possible Pathway Of Action Through Ror2 In Proximodistal Outgrowth Of The Limb, Tiffanie M. Dahl
Role Of Wnt5a And Possible Pathway Of Action Through Ror2 In Proximodistal Outgrowth Of The Limb, Tiffanie M. Dahl
Theses and Dissertations
Despite over 60 years of study, the molecular pathways and mechanisms governing limb outgrowth and patterning remain poorly understood. Fgfs expressed in the AER are known to be necessary and sufficient for proximodistal limb outgrowth and have been proposed to have a chemoattractive role. Wnt5a is a secreted factor which is expressed in a gradient in the distal limb with the highest concentration next to the AER. The presence of the AER is necessary to establish this gradient. Expression of Wnt5a in a concentration dependant manner can be induced in the limb through the implantation of a bead soaked in …
Biological Investigation Of The Stimulated Flapping Motions Of The Moth, Manduca Sexta, Travis B. Tubbs
Biological Investigation Of The Stimulated Flapping Motions Of The Moth, Manduca Sexta, Travis B. Tubbs
Theses and Dissertations
No abstract provided.
Combating Biological Terrorism From Imported Food, Jeffrey S. Nelson
Combating Biological Terrorism From Imported Food, Jeffrey S. Nelson
Theses and Dissertations
There is a threat that a terrorist or terrorist organization will use access to the US food supply to kill or sicken Americans by contaminating imported food products from Mexico. The food that Americans eat is coming more and more often from foreign countries such as Mexico. Foodborne diseases infect nearly fifty million people in the US each year, resulting in over three thousand deaths. There are many terrorist organizations that would like to deliberately contaminate American food. Drug cartels and terrorist organizations currently operate in Mexico, one of the leading food importers into the US. The purpose of this …
A Novel Use Of Digoxin Immune Fab Fragment In Identification And Isolation Of An Endogenous Digitalis-Like Factor Found In Preeclampsia, Moana Lee Hopoate-Sitake
A Novel Use Of Digoxin Immune Fab Fragment In Identification And Isolation Of An Endogenous Digitalis-Like Factor Found In Preeclampsia, Moana Lee Hopoate-Sitake
Theses and Dissertations
The mechanisms mediating the hypertension of preeclampsia (PE) are unclear. Endogenous digitalis-like factors (EDLFs) are specific sodium pump (SP) inhibitors implicated in essential and experimental hypertension, but they have not been fully explored in the setting of PE. This study uses a digoxin antibody Fab fragment to address the question of whether such factors are present and increased in PE, to investigate a possible treatment of PE, and to isolate and characterize all EDLFs present in PE. Sera and placenta from women with PE did show a significant increase in SP inhibition in comparison to women with normal pregnancy and …
Somatoform Disorder: Treatment Utilization And Cost By Mental Health Professions, Lori Barker Morton
Somatoform Disorder: Treatment Utilization And Cost By Mental Health Professions, Lori Barker Morton
Theses and Dissertations
Somatoform disorder is a prevalent mental health disorder in the United States. This disorder costs the United States one billion dollars annually. Medical providers report somatoform disorder is difficult to treat. Previous studies have shown that Cognitive Behavioral Therapy (CBT) is effective at reducing symptoms of somatoform disorder. Unfortunately, little research has been done on treatment outcomes and cost of somatoform disorder, particularly by profession to reduce health care costs for somatoform patients and providers. Administrative data from CIGNA for 149 somatoform disorder cases were analyzed to determine the cost, number of sessions, dropout rates, and recidivism rates for somatoform …
The Effects Of Parental Support, Best Friend Support, And Parental Psychological Control On Loneliness In Latino Adolescents, Denhi Hortensia Chaney
The Effects Of Parental Support, Best Friend Support, And Parental Psychological Control On Loneliness In Latino Adolescents, Denhi Hortensia Chaney
Theses and Dissertations
The current study examined the relationship of parental support, parental psychological control, and best friend support among Latino adolescents and loneliness using self-esteem as a mediating variable. The sample included 839 Hispanic (primarily Mexican) 9th – 12th graders from west Texas area school districts who were given a self-reported survey to assess parental behaviors and adolescent depression. Using structural equation modeling (SEM), findings indicated that neither maternal nor paternal support was found to be significantly related to loneliness in girls. Only maternal support was found to be significantly related to loneliness in boys. On the other hand, neither maternal nor …
The Functions Of Guilt And Shame In Juan José Millás' El Mundo And My Olive-Green Fridge And I: The Posthuman Identity In El Púgil, Constantin Cristian Icleanu
The Functions Of Guilt And Shame In Juan José Millás' El Mundo And My Olive-Green Fridge And I: The Posthuman Identity In El Púgil, Constantin Cristian Icleanu
Theses and Dissertations
In his celebrated 2007 novel El mundo, Juan José Millás tells the story of the development of Juanjo, a simulacrum of himself, and describes a series of negative developments that the protagonist faces in his childhood. While much has been written about Millás and the “testimonial realism” of his literary generation, little has been written about the psychological factors that influence his characters. In this paper I analyze Juanjo's development as understood from the gradation of guilt to shame, depression, and later suicidal thoughts. Because Juanjo is not able to find an appropriate mechanism of release for his guilt, …
Surface Modification, Fabrication, And Characterization Of Silicon, Polymer, And Nanotube Composite Materials, Lei Pei
Theses and Dissertations
In my research, I have performed many characterization and fabrication experiments that are based on tools of analytical chemistry, materials chemistry, and surface science. My research projects are as follows. (1) Fabrication of transparent polymer templates for nanostructured amorphous silicon photovoltaics was done using low-cost nanoimprint lithography of polydimethylsiloxane. This approach provides a test bed for absorption studies in nanostructured film geometries and should result in improved light capturing designs in thin-film solar cells. Nanopatterned polymer films were characterized by scanning electron microscopy and optical measurements. (2) A straightforward method for fabricating freely suspended, thin, carbon nanotube (CNT) membranes infiltrated …