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Linking Photosynthesis Physiology Of Upland Hardwood Reproduction To Ecology And Silviculture In The Arkansas Ozarks, Kutcher K. Cunningham Dec 2014

Linking Photosynthesis Physiology Of Upland Hardwood Reproduction To Ecology And Silviculture In The Arkansas Ozarks, Kutcher K. Cunningham

Theses and Dissertations

Oak (Quercus) forests in the Arkansas Ozarks have been important culturally, ecologically and environmentally for centuries. Historically these forests were fire dependent and dominated by oak species. In the past century, fire suppression and land management have caused these forests to densify. As a result, oaks are increasingly less abundant following disturbance in natural hardwood stands. Many applied ecological studies have explored methods and practices to maintain oak species in newly developing stands. This study attempted to link the mechanistic physiology of oak and non-oak reproduction to the applied ecological work. Varying stand conditions were generated in an undisturbed mature …

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Biological Processing Rhythms In Beginning Readers: A Spectrographic Examination Of Oral Reading Behavior On Texts Of Increasing Difficulty, Laura Juhl Dec 2014

Biological Processing Rhythms In Beginning Readers: A Spectrographic Examination Of Oral Reading Behavior On Texts Of Increasing Difficulty, Laura Juhl

Theses and Dissertations

A qualitative comparative research design grounded in the theory of biological processing rhythms (Holdaway, 1979, Miner, 1903) described oral reading behaviors in different levels of beginning early readers during oral reading of texts of increasing difficulty. Spectrographic analysis with waveform data triangulated with running record data, Slosson Oral Reading Tests (SORT-R3) (Slosson & Nicholson, 1990) and transcriptions allowed an in-depth analysis into the behaviors. Three research questions guided the analysis: (1) How do biological processing rhythms operate with different levels of beginning readers? (2) How do biological processing rhythms, as examined through waveforms of oral reading behavior, operate as beginning …

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Characterization Of Salmonella Enterica Isolates From Food And Clinical Samples: Functionality Of Cytolethal Distending Toxin (Cdt) From Non-Typhi Salmonella Enterica, Ezat Hussain Mezal Dec 2014

Characterization Of Salmonella Enterica Isolates From Food And Clinical Samples: Functionality Of Cytolethal Distending Toxin (Cdt) From Non-Typhi Salmonella Enterica, Ezat Hussain Mezal

Theses and Dissertations

Salmonella enterica is recognized worldwide as a significant cause of both human and animal disease. Recently, many random outbreaks of infections associated with the pathogens have been documented. Thus, state of the art molecular tools are necessary to conduct effective surveillance that would aid monitoring and prevention of disease. In this study, 110 Salmonella enterica serovars (Enteritidis & Javiana) strains isolated from food, environmental and clinical samples were analyzed for genetic diversity, antibiotic resistance, presence of virulence genes, plasmids, and plasmid replicon types. To assess the genetic diversity, pulsed-field gel electrophoresis (PFGE) fingerprinting, multiple-locus variable-number tandem repeat analysis (MLVA) and …

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Myoelectric Prostheses: Novel Methodologies For Enhancing Usability And Control, Ghulam Rasool Dec 2014

Myoelectric Prostheses: Novel Methodologies For Enhancing Usability And Control, Ghulam Rasool

Theses and Dissertations

Control of powered prostheses using the information from leftover muscles in amputees is a challenging problem. I investigated the problem with a view to find clinically reliable and robust schemes that can interpret human intent and control a powered prosthesis in real-time. Recently, pattern classification systems have been suggested to map muscle activation patterns to the human intent (or the movement). However, due to the underlying generic structure, system-specific information cannot be exclusively incorporated into pattern classification algorithms. I have proposed two new methodologies in my research. The first one extended the pattern classification with a new feature set comprised …

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Characterizing Fetal Sleep States Of Iugr And Low-Risk Fetuses Using Fetal Magnetocardiography, Bhargavi Sriram Dec 2014

Characterizing Fetal Sleep States Of Iugr And Low-Risk Fetuses Using Fetal Magnetocardiography, Bhargavi Sriram

Theses and Dissertations

Intrauterine growth restriction (IUGR) is a fetal condition characterized by growth-rate reduction. Afflicted fetuses tend to display abnormalities in heart rate. Hence, studying its heart rate variability (HRV) along with comparisons against normal fetal HRV might give some insight into the heart rate dynamics between the two groups. Heart rate variability (HRV) is one of the prominent markers that could help in identifying fetal distress. Four fetal heart rate patterns were previously defined based on HRV, which can provide clinicians with valuable information regarding fetus health during pregnancy. Past studies that differentiate the HRV with or without considering patterns, have …

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The Roles Of Gsk-3ss And Apc In Cytoplasmic Dynein Regulation, Feng Gao Dec 2014

The Roles Of Gsk-3ss And Apc In Cytoplasmic Dynein Regulation, Feng Gao

Theses and Dissertations

Dynein is a microtubule minus-end directed molecular motor, participating in a broad range of cellular functions, such as organelle transport, cell migration and mitosis. Dynein dysfunction is linked to many diseases including ALS, schizophrenia, Alzheimer’s disease, Parkinson’s disease and cancer. The mechanism of dynein regulation is largely unknown. We have provided evidence that glycogen synthase kinase 3β (GSK-3β) directly regulates dynein in both neurons and non-neuronal cells. GSK-3β interacts with and phosphorylates dynein in vitro. Dynein phosphorylation by GSK-3β reduces its interaction with Ndel1, a regulator contributing to dynein force generation. Dynein motility is stimulated both by pharmacological GSK-3β inhibitors …

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Compositional Traits In Sorghum Bicolor Characterized By Transcriptome, Ionome And Genome-Wide Association Analysis, Nadia Shakoor Dec 2014

Compositional Traits In Sorghum Bicolor Characterized By Transcriptome, Ionome And Genome-Wide Association Analysis, Nadia Shakoor

Theses and Dissertations

To address the challenge of global mineral malnutrition, current biofortification research in crop plants aims to improve mineral concentration and micronutrient bioavailablity via genetic and traditional breeding methods. Many staple food crops are also used as biofuels, and the chemical and mineral composition of these energy crops directly affect biomass quality and subsequent energy output. Identification of genes and QTL that impact mineral and compositional traits in the grain and biomass of major cereals, including sorghum, is fundamental to developing breeding and selection methods aimed at increasing bioavailable minerals and improving biofuel suitability and seed nutritional quality. A combinatorial strategy …

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The African American Male Achievement Dilemma Through The Eyes Of The African American Male Superintendent, J.R. Falor Green Dec 2014

The African American Male Achievement Dilemma Through The Eyes Of The African American Male Superintendent, J.R. Falor Green

Theses and Dissertations

This research study explores the perspective of African American male superintendents on the African American male achievement dilemma. How do African American male superintendents theorize and respond to the underachievement of African American male students? Do their experiences give them greater insight, and how has this potential insight contributed to the implementation of initiatives that have improved the performance of this subgroup? Three major theoretical perspectives were explored during my review of the literature. Critical Race, Social Reproduction, and Oppositional Culture Theory encompassed the most consistent themes during my research, and helped to situate the study within the broader education …

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School-Based Sexuality Education, Gender, And Relationship Self-Efficacy: A Moderated-Mediation Analysis Of Sexual Behavior In First-Year College Students, Sara C. Schmidt Dec 2014

School-Based Sexuality Education, Gender, And Relationship Self-Efficacy: A Moderated-Mediation Analysis Of Sexual Behavior In First-Year College Students, Sara C. Schmidt

Theses and Dissertations

While the effectiveness at abstinence-only versus comprehensive sexuality education in preventing adolescent risky sexual behavior is widely researched, little is known about whether material learned in secondary school sexuality education classes impacts emerging adult sexual behavior in the college environment. Furthermore, research suggests that self-efficacy – or beliefs in one’s abilities to organize and execute actions – may be more critical than knowledge or skills in terms of how individuals enact behavior. We hypothesized a moderated-mediation effect by which the causal impact of type of sexuality education on four different sexual behaviors during the first year in college is transmitted …

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Modeling Mussel Mortality: Investigating The Importance Of Swash And The Potential Implications Of Changing Wave Environments, Shadow Leigh Gulledge Dec 2014

Modeling Mussel Mortality: Investigating The Importance Of Swash And The Potential Implications Of Changing Wave Environments, Shadow Leigh Gulledge

Theses and Dissertations

Rising sea level and increases in temperature are causing biogeographic shifts in intertidal zones and can also lead to shifts in the local vertical zonation of organisms due to changes in body temperature during aerial exposure during low tide. Swash is an important determinant of aerial body temperatures, and vulnerability of intertidal zones to changes in climate could potentially depend on how much and how often animals are cooled by waves. While wave heights (and thus swash) are generally expected to increase with climate change, anthropogenic physical structures, such as breakwaters and wave energy converters, can decrease wave height and …

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Quantitative Comparison Of Time-Frequency Decomposed Gait Emg Signals, L. Patrick Mitchell Dec 2014

Quantitative Comparison Of Time-Frequency Decomposed Gait Emg Signals, L. Patrick Mitchell

Theses and Dissertations

Falls in the senior population represent an immediate threat to both current and future generations’ quality of life. The results of falls can be disastrous, create a long road to recovery, and in many cases result in death. Hypertension represents a difficult-to-quantify condition which is known to contribute to gait and balance dysfunction. Accurate assessment of conditions such as these represents an area of primary investigative need. In order to meet this need, a new experimental setup is developed which combines time-frequency analysis with surface electromyography (sEMG) signals obtained during ambulation. 3-bit pressure data is acquired using a pressure-sensitive mat, …

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Effect Of Primary Care Physician Density On Late Stage Cervical Cancer Diagnosis, Emily Haanschoten Dec 2014

Effect Of Primary Care Physician Density On Late Stage Cervical Cancer Diagnosis, Emily Haanschoten

Theses and Dissertations

INTRODUCTION: Late-stage cervical cancer diagnosis is an important contributing factor to the cervical cancer mortality rate. Screening for cervical cancer is a vital tool in reducing the number of late-stage cases, preventing incident cases and reducing mortality. Access to care is often a significant barrier to receiving these services. Women who have no usual source of care report significantly lower percentages of Pap tests than women who have a usual source. South Carolina ranks 13th in the US in cervical cancer incidence and 7th in cervical cancer mortality. South Carolina also struggles with a primary care physician shortage, ranking 39th …

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'Precious Objects': Strange 'Things' In James And Wharton, John Kinard Dec 2014

'Precious Objects': Strange 'Things' In James And Wharton, John Kinard

Theses and Dissertations

In this work, I attempt to examine the importance of things, the strange agency of objects, which emerges in the literature of the late nineteenth century. To this end, I examine the economy of things in both Henry James and Edith Wharton. I attempt to connect this object agency with the emergent discourses and technologies of the time, and to link these both with media and queer theory.

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Differentiating Self-Reported Imagery Abilities With Functional Magnetic Resonance Imaging, Brian D. Seiler Dec 2014

Differentiating Self-Reported Imagery Abilities With Functional Magnetic Resonance Imaging, Brian D. Seiler

Theses and Dissertations

Motor imagery (MI), a top-down knowledge-driven process involving the deliberate cognitive simulation or rehearsal of an action without engaging in overt physical movements, shares the same neural networks as movement execution improving motor learning and enhancing performance of motor tasks. The capacity to form images is not universal, and is a variable, moderating factor of neural activity impacting intervention effectiveness and distinguishing between individual imagery abilities. Measuring imagery abilities through self-report measures (i.e., MIQ-3 and VMIQ-2) is common, but the importance of behavioral and neuroimaging techniques have also been highlighted. Despite the robustness of these questionnaires, few studies have investigated …

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Examining The Influence Of Healthy Eating Identity On Shopping Behaviors, Jordan Brittingham Dec 2014

Examining The Influence Of Healthy Eating Identity On Shopping Behaviors, Jordan Brittingham

Theses and Dissertations

Eating identity is shown to be a promising measure capable of enhancing our understanding of nutrition behavior. Persons with healthy eating identities are less likely to consume the typical American diet and report healthier diets in general. While there are several studies linking healthy eating identity and diet, there is currently no research examining healthy eating identity in relation to food shopping behavior, an important aspect of nutritional intake. The purpose of this study was to examine the influence of healthy eating identity on shopping behaviors including supermarket utilization, supercenter utilization, likelihood of shopping at the nearest store, distance to …

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Marine Population Connectivity: Range Boundaries And Climate Change, Rhiannon Leigh Rognstad Dec 2014

Marine Population Connectivity: Range Boundaries And Climate Change, Rhiannon Leigh Rognstad

Theses and Dissertations

Population connectivity, particularly in open systems, is an important metric for understanding population-level processes on both ecological and evolutionary timescales. In coastal marine systems, adults are typically sedentary and dispersal occurs primarily during a larval stage when individuals are transported in ocean currents. Because coastal marine populations exist as networks of interconnected subpopulations, variation in the magnitude and extent of population connectivity can have profound effects on population dynamics and species distribution limits. Connectivity is a complex process, affected by a multitude of factors, including adult inputs and physical dispersal, which operate at multiple scales and may interact. This dissertation …

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Periodontal Microorganisms, Obesity, Chronic Inflammation, And Type 1 Diabetes, Georges Joseph Nahhas Dec 2014

Periodontal Microorganisms, Obesity, Chronic Inflammation, And Type 1 Diabetes, Georges Joseph Nahhas

Theses and Dissertations

Periodontal disease is a low-grade chronic inflammation in the tissues surrounding the teeth caused by multiple, mostly gram-negative pathogens. It is associated with diabetes, obesity, and chronic inflammation. The specific roles that periodontal microorganism play in these conditions are not well-studied. Hereby, we explored how periodontal bacteria from sub gingival plaque clustered in youth with and without type 1 diabetes, and how such patterns related to body-mass-index percentile (BMI percentile), C-reactive protein (CRP) and adiponectin. Cross-sectional data were collected from 105 youth with type 1 diabetes and 71 without diabetes. Participants were between 12 and 19 years of age receiving …

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Climatic Controls On Organic Matter Decomposition In Boreal Peatlands, Michael J. Philben Dec 2014

Climatic Controls On Organic Matter Decomposition In Boreal Peatlands, Michael J. Philben

Theses and Dissertations

Boreal peatlands currently contain 550 Pg C and are located at high latitudes where mean annual temperatures are expected to increase by as much as 7°C by the end of the century. There is growing concern that warming will stimulate decomposition, transforming peatlands from a sink to a source of atmospheric carbon dioxide and accelerating climate change. A primary goal of this dissertation was to evaluate the effect of climate change on organic matter decomposition in peatlands. This was achieved by developing and employing biochemical tracers to indicate the extent of peat decomposition across a range of naturally occurring climatic …

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Life Satisfaction And Academic Performance In Early Adolescents: Evidence For Reciprocal Relationships, Zi Jia Ng Dec 2014

Life Satisfaction And Academic Performance In Early Adolescents: Evidence For Reciprocal Relationships, Zi Jia Ng

Theses and Dissertations

Student well-being remains a relatively neglected topic despite its intimate link to positive school outcomes. As academic achievement is the yardstick of student success and school accountability, school-based mental health research and practice have focused primarily on the assessment and treatment of learning and behavioral problems. This shortterm longitudinal study sought to establish the role of student subjective well-being in academic achievement. Based on the engine model of well-being (Jayawickreme, Forgeard, & Seligman, 2012), the study focused on life satisfaction as a process variable and academic performance as an outcome variable. Using two waves (five months apart) of data, the …

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Application Of Various Adsorbents To Remove Micro-Pollutants In Aquatic System, Chanil Jung Dec 2014

Application Of Various Adsorbents To Remove Micro-Pollutants In Aquatic System, Chanil Jung

Theses and Dissertations

Untreated or insufficiently treated pharmaceuticals and endocrine disrupting compounds (EDCs) as well as heavy metals have influenced the ecosystem and their exposures in the water system have threatened human health; causing cancers and adverse health effect to immune system. While various water treatment techniques have been applied to solve this problem, adsorption has been considered as one of the most efficient and manageable water purification techniques. Advanced analysis methods for aqueous contaminants have improved comprehension, allowing proficiency about the fate of trace leveled emerging contaminants, thus allowed to reveal the adsorption mechanisms of each pollutant. This dissertation focuses on the …

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Young, Southern Women's Perceptions Of Stem Careers: Examining Science, Technology, Engineering And Mathematics As A Gendered Construct, Jessica Elizabeth Quinton Dec 2014

Young, Southern Women's Perceptions Of Stem Careers: Examining Science, Technology, Engineering And Mathematics As A Gendered Construct, Jessica Elizabeth Quinton

Theses and Dissertations

Career interests develop over a lifetime and tend to solidify during late adolescence and early adulthood (Lent, Brown, and Hackett, 2002). The primary purpose of the present qualitative study, which is framed in Feminist Standpoint Theory (Haraway, 1988; Harding, 2007; Naples, 2007; Richardson, 2007), is to understand how eighthgrade, young women in a suburban, public, southern, middle school the South Carolina County School District (CCSD) (pseudonym) perceive their accessibility to Science, Technology, Engineering, and Mathematics (STEM) courses and careers. The secondary purpose is to understand these young women’s “perceptions and unconscious beliefs about gender in science and mathematics” and how …

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Cationic Metallocene-Containing Polymers: From Synthesis To Applications, Jiuyang Zhang Dec 2014

Cationic Metallocene-Containing Polymers: From Synthesis To Applications, Jiuyang Zhang

Theses and Dissertations

Metallopolymers, with the combination of metals and polymeric framworks, have attracted a lot of attention during the past decades. The development of metallopolymers has been largely driven by the desire to combine the synthetic efficiency and versatility of an organic polymer framework with the unique redox, responsive and catalytic properties of inorganic metals. Among different kinds of metallopolymers, metallocene-containing polymers， have been widely utilized for applications ranging from electrochemical sensors to templates for advanced inorganic catalysts to battery materials, due to their unique physicochemical properties. In the first part of my thesis, we showed controlled/living polymerization strategies to prepare well-defined …

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Ferric Reductases And Transporters That Contribute To Mitochondrial Iron Homeostasis, Anshika Jain Dec 2014

Ferric Reductases And Transporters That Contribute To Mitochondrial Iron Homeostasis, Anshika Jain

Theses and Dissertations

Iron (Fe) is the fourth most abundant element in the Earth’s crust, yet the availability of Fe to plants is often limited. This is because in most soil types, Fe precipitates as ferric-oxyhydroxy complexes, making it unavailable for uptake by plants. While the mechanisms involved in Fe uptake from the soil are relatively well understood, the mechanisms involved in its further distribution to the aerial portion of the plant and to subcellular compartments are not fully understood. During Fe deprivation, plants up-regulate root Fe acquisition machinery. How plants sense Fe deprivation and tie the Fe status of the plant to …

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Toward The Combinatorial Development Of Hydrophobic-Tagged Antifolate-Directed Degradation Of Human Thymidylate Synthase, Daniel J. Menasco Dec 2014

Toward The Combinatorial Development Of Hydrophobic-Tagged Antifolate-Directed Degradation Of Human Thymidylate Synthase, Daniel J. Menasco

Theses and Dissertations

Direct post-translational control over a protein of interest (POI) can be exploited by manipulating the cells protein quality-control systems responsible for either intracellular turnover through ubiquitination (POI half-life) or repairing and degrading misfolded proteins.1 In an effort to target and degrade a high value POI we selected the enzyme human thymidylate synthase (TS) for post-translational degradation through ligand-directed ubiquitination and hydrophobic tagging. Thymidylate synthase catalyzes the reductive methylation of 2’-deoxyuridine monophosphate (dUMP) to 2’-deoxythymidine monophosphate (dTMP). As the de novo source of dTMP the regulation of intracellular TS is strictly controlled by ubiquitinindependent proteasomal degradation mediated by an internal TS-degron …

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Molecular Mechanisms Of Gap Junction Regulation By The E3 Ubiquitin Ligase Wwp1, Measho Hagos Abreha Dec 2014

Molecular Mechanisms Of Gap Junction Regulation By The E3 Ubiquitin Ligase Wwp1, Measho Hagos Abreha

Theses and Dissertations

Ubiquitylation is a post-translational modification that influences a wide variety of cellular processes including protein degradation, protein subcellular localization, cell cycle progression, transcription, and DNA damage repair. Covalent attachment of the small ubiquitin molecule to a target protein involves the sequential action of three enzymes (E1, E2, and E3). In this process, substrate specificity is conferred by the E3 ligase. Our work has focused on the function of one such E3 ubiquitin ligase, WWP1. Known targets of WWP1 include cell cycle proteins, tumor suppressors, and transcription factors that promote differentiation of mesenchymal stem cells to the osteoid lineage. Recently, we …

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High-Performance Meta-Genomic Gene Identification, Ibrahim Savran Dec 2014

High-Performance Meta-Genomic Gene Identification, Ibrahim Savran

Theses and Dissertations

Computational Genomics, or Computational Genetics, refers to the use of computational and statistical analysis for understanding the structure and the function of genetic material in organisms. The primary focus of research in computational genomics in the past three decades has been the understanding of genomes and their functional elements by analyzing biological sequence data. The high demand for low-cost sequencing has driven the development of highthroughput sequencing technologies, next-generation sequencing (NGS), that parallelize the sequencing process, producing thousands or millions of sequences concurrently. Moore’s Law is the observation that the number of transistors on integrated circuits doubles approximately every two …

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The Role Of Lis1 In Adult Mammalian System, Xu Gao Dec 2014

The Role Of Lis1 In Adult Mammalian System, Xu Gao

Theses and Dissertations

Lis1 haploinsufficiency in humans results in a “smooth brain” phenotype called lissencephaly, and also causes severe cognitive and motor impairments and epilepsy. Seizure severity and frequency typically worsens with time; patients often die within the first decade due to seizure-induced aspiration and pneumonia. Various mouse models have been used to examine the role of Lis1 during brain development, and it is clear that Lis1 regulates a microtubule motor, cytoplasmic dynein. Intriguingly, Lis1 expression remains high in adult brains indicating that it plays a role in mature systems. Indeed, our group found that Lis1 and several related proteins regulate dynein-dependent axon …

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Leadership Perspectives On International Education For Public School Students In South Carolina: Two Case Studies, Frederick Eugene Brown Dec 2014

Leadership Perspectives On International Education For Public School Students In South Carolina: Two Case Studies, Frederick Eugene Brown

Theses and Dissertations

This study explores how two rural public school districts in South Carolina conceptualize and implement an international education, according to the perspectives of administrators and teachers. This comparative case study of two public school districts spans the districts’ elementary, middle, high and career center schools and seeks to understand how the presence of a major multinational corporation influences school internationalization. The data on their perspectives on internationalization were drawn from interviews. I interviewed the school principal and teachers involved in internationalizing the curriculum, policy and practice in each of the ten schools. In addition to school level personnel, I interviewed …

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Novel Biofabrication Technologies To Recapitulate In Vivo Geometries In Collagen Hydrogels, Veronica Rodriguez-Rivera Dec 2014

Novel Biofabrication Technologies To Recapitulate In Vivo Geometries In Collagen Hydrogels, Veronica Rodriguez-Rivera

Theses and Dissertations

Tissue engineering and regenerative medicine aims to restore form and function to tissues that have been lost or damaged due to disease, congenital defect, or trauma. Biomaterials suitable to restore these complex tissues need to provide a balance between chemical and mechanical properties, providing accurate cell-matrix interaction and induce in vivo behaviors such as proliferation, differentiation and migration. It also requires that physical and chemical cues be presented to the body in the proper temporal and spatial pattern. The extracellular matrix exerts forces that are transmitted through focal adhesion causing changes in the cell behavior. The hypothesis for this dissertation …

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Diversity, Genetics, And Health Benefits Of Sorghum Grain, Davina Rhodes Dec 2014

Diversity, Genetics, And Health Benefits Of Sorghum Grain, Davina Rhodes

Theses and Dissertations

Staple cereal crops provide the majority of nutrients to the world's population, and thus, can significantly impact human nutrition and health. Phenotypic and genetic diversity within a crop can be useful for biofortification and crop improvement, but quantitative phenotyping is needed to identify varieties with high or low concentrations of a nutrient of interest, and to identify alleles responsible for quantitative trait variation of the nutrient. Sorghum [Sorghum bicolor (L.) Moench] is a diverse and widely adapted cereal crop that provides food for more than 500 million people in sub-Saharan Africa and Asia, and is becoming increasingly popular in specialty …

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