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The Relationship Between Religiosity And Health-Promoting Behaviors Of Pregnant Women At Pregnancy Resource Centers, Natalie Ann Cyphers

Theses and Dissertations

Introduction: While religiosity (e.g. prayer, attending church) has been reported to be related to health behaviors in pregnant women, whether religiosity was related to health-promoting behaviors in pregnant women at Pregnancy Resource Centers (PRC) had not been previously studied. The purpose of this research study was to explore the relationship between religiosity and health-promoting behaviors of pregnant women at PRC. PRC are Christian community-based centers with a focus on meeting needs of pregnant women.

Methods: Pender’s Health Promotion Model guided this descriptive correlational study. A consecutive sample included pregnant women who knew they were pregnant at least two months, could …

"A Picture Terrible In Its Significance": Jack Johnson, Interracial Relationships, And Methods Of White Social Control In Early Twentieth-Century America, Aimee M. Duchsherer

Theses and Dissertations

In early twentieth-century America, white society used white female purity, psychological and racial pressures, and intense physical violence as methods by which to control the sexual behavior of black men and white women. An exploration of the case study of African American boxer Jack Johnson reveals the use of these tools in the public response to his relationships with three white women: Belle Schreiber, Etta Duryea, and Lucille Cameron. As Johnson challenged white men in the boxing ring, he further challenged their supposed racial superiority through his blatant, public sexual relationships with and marriages to white women. Using legal documents …

The Effect Of 3d Collagen Scaffolds On Regulating Cellular Responses, Chad Simmons

Theses and Dissertations

Epithelial cells, as well as other differentiated cell types, remodel surrounding collagen in vitro, to self organize into 3D structures. When placed on-top or inside of a collagen hydrogel, cells organize into a toroid or spheroid form. It is not clearly understood how these cell types modulate surrounding collagen to form 3D shapes. The goal of this project was to determine if cell type, collagen type, or cell placement are factors that can alter how cells reorganize and remodel collagen hydrogels. We hypothesize that the positioning, cell type and the type of collagen they are in contact with affect the …

A Longitudinal Examination Of The Mediating Role Of Social Problem Solving Between Parental Attachment And Early Adolescents’ Life Satisfaction, Xu Jiang

Theses and Dissertations

Both attachment theory and empirical evidence indicate that the quality of parental attachment profoundly influences many different aspects of adolescent life. However, one area that has been somewhat neglected in the literature is the discovery of the psychosocial mechanisms that account for the link between parental attachment and important adolescent developmental outcomes, such as social problem solving (D’Zurilla & Goldfried, 1971) and life satisfaction (LS: Diener, 1994). Driven by the conceptual framework of development of LS proposed by Evans (1994), Attachment Theory and Social Problem Solving Theory, a mediation model was hypothesized to explore the link between parental attachment and …

Material Considerations For Development Of 3d Printed Bronchial And Tracheal Stents, Nidah M. Hussain

Theses and Dissertations

Tracheobronchial malacia is a commonly under-diagnosed condition that results in difficulty breathing. The use of a tracheobronchial stent is the best course of treatment for patients whose quality of life has deteriorated due to malacia; unfortunately stents need replacing after issues with inflammation, migration, or eventual stent-breakdown resulting in fistula formation.

The purpose of this thesis is to use three-dimensional (3D) printing technology to improve on existing stents through designing and printing a bioresorbable/biodegradable tracheobronchial stent that can treat tracheobronchial malacia. This was undertaken by testing three biologically favorable materials, type I collagen, polycaprolactone (PCL), and thermoplastic polyurethane (TPU), with …

Working Memory In Children With Neurocognitive Effects From Sickle Cell Disease: Contributions Of The Central Executive And Processing Efficiency, Kelsey Erin Smith

Theses and Dissertations

Children with sickle cell disease (SCD) are at risk for neurocognitive impairment due to disease effects including stroke, sleep disordered breathing, anemia-induced hypoxia, and small vessel occlusion. In particular, problems in working memory are an area of concern due to the importance of this construct in determining intelligence and academic functioning. According to Baddely’s model, working memory is composed of verbal and spatial working memory, but it is unclear whether one aspect of working memory is more impacted than another in children with SCD. In addition, little is known about the role of two key components in SCD-related working memory …

Figure And Flora, Caleigh Eveleth Goold

Theses and Dissertations

‘Figure and Flora’ is an exploration of the visual relationship between the human figure and various forms of plant life. It is an exercise in appreciation of the subtle nuances in color, shape and form of the human body which can bear a striking resemblance to vegetation that one would encounter in everyday life. Because we are such visual creatures, recognizing the aesthetic similarities can be an effective first step in realizing the inherent and biological similarities as well. This exhibit is meant to remind people that they are related to many more varied life forms than they may be …

Bottomfeeders, William Linn

Theses and Dissertations

Bottomfeeders is a collection of short fiction. It includes stories concerning life, death, hoboes, wrestling, videogames, and cropdusters, among other things. It is both very serious and impossibly dumb, as is the way of things.

The Evolutionary Biology Of Vision In Daphnia, Christopher S. Brandon

Theses and Dissertations

Eyes have attracted the attention of evolutionary biologist since the field’s infancy. In On the Origin of Species, in fact, Darwin famously remarked on the proposition that natural selection could engineer the eye, saying “[it is] absurd in the highest possible degree.” Though, he goes on to explain, beautifully and simply, how his theory of evolution by natural selection could produce such an organ. Indeed, eyes are remarkable examples of complex information acquisition systems that have evolved from simple beginnings. Eyes allow animals to extract environmental information from light, which informs physiological and behavioral responses to resources, predation, and mates. …

Antecedents Of Adolescents' Hope: Personality, Parental Attachment, And Stressful Life Events, Kristin L. Otis

Theses and Dissertations

In the past decade, psychology has concentrated on the importance of identifying psychological qualities in individuals that indicate positive mental health and flourishing. Hope has been proposed to be one of these qualities (Day, Hanson, Maltby, Proctor, & Wood, 2010; Marques, & Lopez, 2014). This study examined the relations among parental attachment, stressful life events, personality variables, and hope in a sample of 647 middle school students from one middle school in a Southeastern US state. The results showed statistically significant correlations between hope and all four predictor variables as well as students’ grade levels and socioeconomic status (SES). The …

Complexity In Overmarsh Circulation, Jessica Chassereau Sullivan

Theses and Dissertations

Overmarsh circulation is highly complex with variations in current direction over very short timescales and flowpaths that differ substantially between flood and ebb cycles. Understanding such flow complexities in salt marshes is important because they inherently impact the distribution of sediment, larvae and nutrients throughout the marsh, and hence, the ecogeomorphic feedbacks that control landscape evolution. The purpose this Ph.D. research is to quantitatively evaluate the effects of salt marsh topography on overmarsh circulation in a Georgia salt marsh. This dissertation is comprised of three parts. First, digital elevation models (DEMs) were compared to characterize how well airborne lidar (light …

Inquiry-Based Teaching In The College Classroom: The Nontraditional Student, Daniel A. Kiernan

Theses and Dissertations

Decline in the economic realm often bolsters an increase of nontraditional student enrollments in colleges and universities (Windolf, 1992). Many of these students, who do not desire to major in some scientific area, find themselves struggling in required science courses. Over the last decade, science departments of higher education have been adjusting their curriculum to include inquiry in the college science classroom. Although inquiry-based teaching has been shown to be very academically positive in science classrooms from K-12, “at the college level the data are mixed as to whether increasing inquiry instruction can significantly change students’ learning or attitudes toward …

Healthy Eating And Physical Activity Environmental And Policy Assessment – Measurement Issues And Implications, Rahma Jamea Yousef Ajja

Theses and Dissertations

Current research has suggested that supportive healthy eating and physical activity (HEPA) policy and practice environments play a significant role in shaping the physical activity levels and eating habits of youth. Subsequently, a wide array of audit tools assessing policy and practice environment characteristics across settings that care for youth were developed. However, the extent that available audit tools accurately reflect the policy environment characteristics of the settings that care for the youth population remains unknown. Therefore, this dissertation encompasses four studies. The purpose of the first study was to examine the measurement properties of audit tools currently in use …

Exploring Communication Patterns In The Discussion Of Maternal Pku Syndrome Between Parents And Daughters, Hannah Beth Andrews

Theses and Dissertations

Maternal PKU syndrome is the collection of features and birth defects that arise from uncontrolled phenylalanine levels in a pregnant woman with phenylalanine hydroxylase (PAH) deficiency, previously known as phenylketonuria (PKU). Currently, the literature is lacking in exploring what young women are being told about maternal PKU syndrome. In this study, communication patterns between parents and their daughters about maternal PKU syndrome were investigated through an online survey completed by parents. The survey assessed parents’ level of comfort with this topic, the information they discussed with their daughter and the resources they accessed. Followup interviews were conducted with participants to …

Evaluating Muscle Fiber Architecture, Morgan Ashley Flahive

Theses and Dissertations

Mastication is the first step in the preparation of food for digestion. The masticatory anatomy of several families of Carnivorans (i.e., Family Canidae, Family Mustelidae, Family Hyaenidae, and Family Ursidae of the order Carnivora) will be compared in this study. The goal is to better understand masticatory adaptations through an examination of bite force and muscle fiber architecture in the various groups of carnivores, and to provide a proper protocol in acid dissection of fiber architecture.

Fabrication And Characterization Of Graphene Based Biocompatible Ion-Sensitive Field Effect Transistor (Isfet), Rina Patel

Theses and Dissertations

Graphene, a two-dimensional material with a high surface to volume ratio, has drawn extensive research enthusiasm for applications in the field of electronic sensors. The special material properties that make graphene a highly promising material include its biocompatibility, very high mobility, low 1/f and thermal noise, modulation of carrier concentration and fermi level by electrical, optical, and chemical means. To exploit these properties for practical applications a large area high quality graphene, transferred on appropriate substrates, is required. In this work, high quality single monolayer graphene (determined from Raman spectroscopy) has been synthesized by chemical vapor deposition (CVD) technique for …

Addressing Disparity: One Unique School’S Efforts To Provide Holistic Education In A Low-Income, Black Community, Allison Anne Parsons

Theses and Dissertations

Schools are meant to provide an equal opportunity for achievement to all students. The reality is that school policies and practices, which govern not only child education but also child health, parenting practices, and other social issues, are based on ideologies of the dominant culture creating an environment the perpetuates current social hierarchies. By doing so, this not only limits minority populations’ access to the opportunities associated with education but also access to health, as education and health are strongly and positively linked.

This study used qualitative methods including ethnography to explore how racism was perpetuated through the dominant discourses …

Adiponectin And Selenium Rich Diet Can Act As A Complimentary Medicine In The Treatment Of Intestinal And Chronic Inflammation Induced Colon Cancer, Arpit Saxena

Theses and Dissertations

Colon cancer is the second largest cause of cancer death in United States. Chronic inflammation and obesity predispose patients to colon cancer. Adipose tissue is a source of bioactive substances called adipokines. Adiponectin (APN), an adipokine has anti-inflammatory property and found at lower levels in obese patients. Selenium (Se), a trace mineral and a dietary supplement, is inversely associated with cancer risk and possess anti-inflammatory and anti-carcinogenic properties. The overall purpose of this dissertation is to determine if chronic inflammation leading to colon and intestinal cancer are regulated by APN or Se rich diet or both. The working hypothesis is …

Knowing In America: The Enlightenment, Science, And The Early Republic, Timothy K. Minella

Theses and Dissertations

This dissertation analyzes practices of science and technology in the early United States as windows onto the American Enlightenment. Although scholars have emphasized the important impact of Enlightenment thought on the American founding, the historiography tends to argue for the decreasing influence of the Enlightenment on American culture as the nineteenth century progressed. In addition, scholars tend to see a decline in American science after Benjamin Franklin as nineteenth-century Americans began to focus primarily on the practical problems of everyday life. I question these interpretations by connecting scientific practice in the Early Republic with transatlantic Enlightenment thought and analyzing American …

Species Responses To Climate Change And Environmental Heterogeneity: A Multi-Focal Approach, Megan Riley

Theses and Dissertations

Changes in global climate trends have the potential to influence diverse ecosystems at multiple levels of organization, from the species to the community. Changes in other environmental variables, such as those resulting from pollution and habitat modification, also have the potential to impact species fitness and alter species interactions. This dissertation employs a multi-focal approach to investigate species responses to two main topics: climate change and environmental heterogeneity. To investigate the first topic, this work focuses on the climate change-induced range expansion of the mangrove tree crab Aratus pisonii into novel salt marsh habitats. It investigates latitudinal patterns of life …

The Recovery Of Gut Barrier Function With Selenium Rich Diet In Acute Dss-Induced Colitis, Sarah Depaepe

Theses and Dissertations

Background: Acute Dextran Sodium Sulfate (DSS)-induced colitis is an inflammatory ailment limited to the colon. It works to destroy the morphology and gut barrier goblet and epithelial cells that aid in providing homeostasis. Selenium (Se) is an essential micronutrient that has anti-inflammatory and antioxidant properties and is known to play a role in reducing inflammation in areas elsewhere in the body. The current study is focused on how Se alters gut barrier permeability and functionality related to the recovery of tight junction regulation and mucin secretion. Methods: C57BL/6 mice were randomly placed into control (normal water) and 2% DSS water …

Trees, Partitions, And Other Combinatorial Structures, Heather Christina Smith

Theses and Dissertations

This dissertation contains work on three main topics.

Chapters 1 through 4 provide complexity results for the single cut-or-join model for genome rearrangement. Genomes will be represented by binary strings. Let S be a finite collection of binary strings, each of the same length. Define M to be the collection of medians – binary strings μ which minimize Sigma v belongs to S H(μ,v) where H is the Hamming distance. For any non-negative function f(x), define Z(f(x), S) to be (Sigma μ belongs to M) (Pi v belongs to S)f(H(μ,v)). We study the complexity of calculating Z(f(x), S), with respect …

Iii-V Nitride Based Microcantilever Heaters For Unique Multimodal Detection Of Volatile Organic Compounds At Low Temperature, Ifat Jahangir

Theses and Dissertations

Detection of volatile organic compounds (VOCs), which are widely used in industrial processes and household products, is very important due to significant health hazards associated with them. VOCs are commonly detected using photo-ionization detectors (PIDs), suspended hot bead pellistors, or heated metal oxide semiconductor functionalization layers. However, these techniques used for detecting VOCs often suffer from one or more of the following issues - high power consumption, limited selectivity, complicated functionalization technique and expensive characterization tools. On the other hand, microcantilevers offer excellent avenues for molecular sensing that arises out of their high sensitivity to various physical parameter changes induced …

Tropes Of Blood, Body And The Ground Of The Law: Becoming, Being And Beyond Wife On The Early Modern Stage, Emily Faye Murray

Theses and Dissertations

This project focuses on the representation of women on the early modern stage in three exemplary texts: the anonymous domestic tragedy Arden of Faversham, and two city comedies, Thomas Dekker’s The Shoemaker’s Holiday and Dekker and Thomas Middleton’s The Roaring Girl. Whether playing the role of adulterous wife, performing the role socially striving wife, or resisting the role of laboring wife, these female characters were on stage not only for entertainment, but also for examination and scrutiny by an early modern audience. Playwrights used characterizations of women and wives and their relationships to the economy as vehicles through …

Soil Arsenic And Lead Concentrations And Preterm Birth: Investigating Racial Disparities, Sources, Neighborhood Effects, And Spatial Patterns, Pamela Harley Thornton Davis

Theses and Dissertations

Preterm birth, generally defined as birth at <37 weeks of gestation, is an important public health issue that has multiple risk factors related to characteristics of both the mother and her environment. The purpose of this dissertation was to examine potential sources of spatially interpolated (kriged) environmental concentrations of arsenic (As) and lead (Pb) in residential soils and preterm birth in a Medicaid population of mothers giving birth in South Carolina (SC) from 1996-2001. The first objective was to investigate if a racial disparity existed for estimated soil As and Pb concentrations, after adjusting for proximal and distal sources of these metals (including distance and direction to industrial facilities) in a subset of SC Medicaid mothers living in areas of SC where soil samples were collected and analyzed for these metals. The second objective was to test the hypothesis that estimated soil As and Pb concentrations were associated with increased odds of early (<34 weeks) and late (34-36 weeks) preterm births in the same subset of SC Medicaid mothers, after adjusting for individual and neighborhood level risk factors, and examine if measure of neighborhood deprivation and racial residential segregation modified these associations. The third objective was to examine if early and all preterm births, aggregated at the county level, varied spatially and/or temporally in SC for all Medicaid mothers giving birth from 1996-2001 in Bayesian models.

For the first objective, black mothers had significantly higher estimated As and Pb soil concentrations than white mothers in the study population (adjusted betas were 0.12 and 0.22 for As and Pb, respectively; all p<0.006), and proximal sources of metals (e.g., percent of Census block group are covered by roads) were more strongly associated with estimated soil As and Pb concentrations than composite As and Pb releases from industrial facilities categorized by distance from and direction to Census block groups in which maternal residences were located.

For the second objective, estimated soil concentration of neither As nor Pb were associated with increased odds of early or late preterm birth after adjusting for maternal and neighborhood level risk factors. Only individual level covariates were associated with these birth outcomes, and associations were stronger for early as compared to late preterm births. Neighborhood deprivation and racial …

Extensive Genome Rearrangements Of Caulobacter K31 And Genomic Diversity Of Type B3 Bacteriophages Of Caulobacter Crescentus, Kurt Taylor Ash

Theses and Dissertations

The genus Caulobacter is found in a variety of habitats and is known for its ability to thrive in low-nutrient conditions. K31 is a novel Caulobacter isolate that has the ability to tolerate copper and chlorophenols, and can grow at 48°C with a doubling time of 40 h. K31 contains a 5.5 Mb chromosome that codes for more than 5500 proteins and two large plasmids (234 and 178 kb) that code for 438 additional proteins. A comparison of the K31 genome and the Caulobacter crescentus NA1000 genome, the representative strain and most well studied isolate of the Caulobacter genus, revealed …

Fate And Behavior Of Silver Nanoparticles To The Estuarine Organisms, Prorocentrum Minimum And Crassostrea Virginica, Shelby Victoria Butz

Theses and Dissertations

Nanoparticles are known to be entering the environment and are shown to have adverse effects on aquatic organisms (Fabrega et.al. 2011, Lapresta-Fernandez et.al. 2012, Matranga and Corsi 2012, Moore 2006). The purpose of this study was to quantify the uptake of AgNPs by two estuarine organisms and determine the associated toxic effects of accumulation. There are multiple procedures for nanoparticle (NP) synthesis that involve various core and surface materials, which result in various characteristics such as size, shape, and surface coating. In this study silver nanoparticles (AgNPs) were synthesized by a chemical reduction of silver salts and characterized in stock …

An Applied Mathematics Approach To Modeling Inflammation: Hematopoietic Bone Marrow Stem Cells, Systemic Estrogen And Wound Healing And Gas Exchange In The Lungs And Body, Racheal L. Cooper

Theses and Dissertations

Mathematical models apply to a multitude physiological processes and are used to make predictions and analyze outcomes of these processes. Specifically, in the medical field, a mathematical model uses a set of initial conditions that represents a physiological state as input and a set of parameter values are used to describe the interaction between variables being modeled. These models are used to analyze possible outcomes, and assist physicians in choosing the most appropriate treatment options for a particular situation. We aim to use mathematical modeling to analyze the dynamics of processes involved in the inflammatory process.

First, we create a …

The Characterization Of A Putative Protease Expressed By Sneathia Amnii, Rana Mehr

Theses and Dissertations

Preterm birth, birth prior to 37 weeks gestation, is the leading cause of neonatal mortality and morbidity worldwide. While the uterine cavity and amniotic fluid largely remain sterile throughout gestation, bacterial infections can occur and are associated with preterm birth and/or preterm premature rupture of the fetal membranes (PPROM). Sneathia amnii can be detected as a component of the vaginal flora in healthy women; however, it’s also associated with bacterial vaginosis and preterm birth. Sn35, an isolate of S.amnii, was identified and sequenced through the Vaginal Human Microbiome Project at VCU. Our objective was to classify potential virulence determinants …

Immunotherapy Of Cancer: Reprogramming Tumor/Immune Cellular Crosstalk To Improve Anti-Tumor Efficacy, Kyle K. Payne

Theses and Dissertations

Immunotherapy of cancer has been shown to be promising in prolonging patient survival. However, complete elimination of cancer and life-long relapse-free survival remain to be major challenge for anti-cancer therapeutics. We have previously reported that ex vivo reprogramming of tumor-sensitized immune cells by bryostatin 1/ionomycin (B/I) and the gamma-chain (γ-c) cytokines IL-2, IL-7, and IL-15 resulted in the generation of memory T cells as well as CD25+ NKT cells and CD25+ NK cells. Adoptive cellular therapy (ACT) utilizing these reprogrammed immune cells protected FVBN202 mice from tumor challenge, and overcame the suppressive functions of myeloid-derived suppressor cells (MDSCs). We then …