Digital Commons Network^™

Synthesis Of Bipyridine Carbohydrate Receptors, Maxwell Addo

Theses and Dissertations

Macrocyclic molecules consisting of aromatic groups with amino side chains are known to bind selectively to carbohydrates, mainly monosaccharides and oligosaccharides. Some of these macrocyclic molecules, for example, Pyridine-based and Naphthyridine-based macrocyclic structures, behave like carbohydrate receptors and bind selectively to carbohydrates in aqueous solutions through hydrogen bonding, hydrophobic and electrostatic interactions. Bipyridine receptors mimic natural lectins. A bipyridine receptor was designed and synthesized from Tris(2-aminoethyl)amine and 2,2-bipyridine-4,4-dicarboxyaldehyde. The receptor was purified and characterized using extraction, HPLC (High Performance Liquid Chromatography), NMR (Nuclear Magnetic Resonance) spectroscopy and ESI-MS (Electrospray Ionization Mass Spectrometry). Masses and peaks obtained matched the expected structure …

Religion, Acculturarive Stress And Immigration Generations Among Hispanics In The Texas-Mexico Border: Predictors Of Attitudes Toward Substance Use, Diana Karen Vaquera Santos

Theses and Dissertations

Understanding Hispanic cultural aspects and their influence on mental health will be crucial to better serve Hispanics (Kouyoumdjian, et al., 2003). Alcohol and drug use disorders have been identified as a major health problem in the U.S. Hispanic population (Vega, Sribney, & Achara-Abrahams, 2003). Regarding substance use, religiosity tends to be a protective factor among Hispanics. Acculturation and acculturative stress have been found as additional factors associated with substance use. Moreover, an individual’s intentions to engage in certain behavior can be defined by their attitudes toward this behavior and their perceived subjective norms regarding such behavior (Lorenzo-Blanco, et al., 2016). …

Evolution Of Endurance Running Genes Across Primates, Natalia T. Grube

Theses and Dissertations

The endurance running hypothesis has emerged as a key idea to explain several unique anatomical, physiological, and genetic features of modern humans—among these features is the evolution of ACTN3 (Bramble & Lieberman 2004, Nature), a gene linked to human athletic performance. An additional gene linked to human endurance performance is ACE. Because endurance running is a uniquely human trait, I predicted that ACE and ACTN3 genes would be evolving adaptively in the human lineage when examined in a wider primatological framework. To test this I compiled ACE and ACTN3 genes from 14 primate species and phylogenetically tested if these genes …

The Impact Of Community-Based Training Outreach In Improving Water Quality, Health, And Sanitation In Kenya, Lavender Matuyia Ntaoti

Theses and Dissertations

Water is an important component of the human body. A greater percentage of the body comprises of water. Digestion, brain function, movement, and sweating among others are the basic functions of the human body that require water. Often, water quality is neglected in developing countries such as Kenya, Uganda, and Tanzania. Many individuals in these countries understand the importance of having accessible water but do not prioritize the quality and the sources of the water available to them. Public health scholars endorse education, training, and sanitary infrastructure to promote awareness and importance of water quality. To address an existing waterborne …

The Effects Of Dixie Harrow Treatments On Greater Sage-Grouse Resource Selection And The Nutritional Value Of Sagebrush During Winter, Jason Alan Wood

Theses and Dissertations

Sagebrush (Artemisia spp.) is an important source of food and cover for many animals, especially during winter months. Understanding how wildlife species respond to sagebrush management actions can help improve conservation planning. Dixie harrow is a method of improving spring/summer habitat for many herbivores by reducing sagebrush cover to stimulate the growth of grasses and forbs. These treatments, however, may influence the quantity and quality of sagebrush available to greater sage-grouse (Centrocercus urophasianus; hereafter, sage-grouse) during winter. We evaluated the effects of Dixie harrow on sage-grouse resource selection during winter (Chapter 1) and on the nutritional value of sagebrush (Chapter …

Exposure To Suicidal Behavior Predicts A Suicide Attempt, Depending On Past Psychiatric Diagnosis, Emily A. Kline

Theses and Dissertations

We hypothesized that adolescents with a psychiatric diagnosis that were exposed to a suicide attempt and/or suicide death are at risk for future suicide attempts. Exposure to suicidal behavior did not predict future suicide attempts, however the interaction between having a psychiatric diagnosis and exposure significantly predicted future suicide attempts.

Identification Of Factors Contributing To Musculoskeletal Injuries In Military Basic Trainees, Amy Fraley Hand

Theses and Dissertations

Due to the physical activity requirements of the United States (U.S.) Armed Forces, there is a concerning incidence rate of musculoskeletal injuries in military personnel. In the basic trainee population specifically, multiple studies have reported a range of exercise- related injury incidence from 14% to 42% in males and 27% to 61.7% in females. Depending on the severity, these injuries can exclude basic trainees from participation, ultimately altering career trajectory and creating the possibility of long-term disability. The studies of this dissertation examine variations in muscle strength, flexibility, and dynamic postural control as a means to identify those basic trainees …

An Observational Study Of Physicochemical Changes In Cheddar Enzyme-Modified Cheese During Incubation, David Gary Doxey

Theses and Dissertations

This study is an observation of the various physicochemical changes that occur in enzyme-modified cheese (EMC) during the incubation step of production. The purpose of this study was an attempt to gain a better understanding of the changes that occur due to enzymatic reactions during EMC production. A standard EMC batch was prepared with the addition of two exogenous enzymes, a lipase and a protease (LP). Two additional treatment batches had either only a lipase (L) or a protease (P) added individually. Batches were prepared in duplicate with each replicate performed on different days. Each batch was incubated at 42±0.5°C …

Multispecies Character Displacement In Mexican Poeciliopsis Fishes, Andrea J. Roth

Theses and Dissertations

Competition has long been recognized as a central force in shaping evolution, particularly through character displacement. Yet research on character displacement is biased as it has focused almost exclusively on pairs of interacting species while ignoring multispecies interactions. Unfortunately, communities are seldom so simple that only pairs of species interact, and it is not clear if inferences from pairwise interactions are sufficient to explain patterns in nature. A more realistic approach is to ask how traits evolve when multiple species interact. Here I explore the importance of multispecies competitive interactions on trait evolution in four congeneric species of livebearing fishes …

Skill Acquisition And Behavior Change Following An Exercise Bout In Children With Autism Spectrum Disorder, Erika Jaci Richards

Theses and Dissertations

The purpose of the study was to determine if antecedent bouts of exercise, through the means of a basketball practice, are beneficial to 5 children aged 8 to 11 with autism spectrum disorder (ASD) in decreasing competing behaviors (e.g., stereotypy, disruptive behaviors). Additionally, basketball skill mastery was measured. Antecedent exercise was corroborated by measuring heart rate. The results of the study indicate that antecedent exercise decreased disruptive behaviors and had no effect on stereotypic behaviors. Of the 5 participants, 4 of them had heart rate levels that indicated they were engaged in moderate to vigorous physical activity. All 5 participants …

Impacts Of Novel Fire And Herbivory Regimes On Snow-Waterresources And Resilience Of Aspen Forests, Jordan Daniel Maxwell

Theses and Dissertations

Human activities and expansion have created novel disturbance patterns across Earth’s landscapes. Disturbance is an ecological interruption after which ecosystem recovery or transition into a new state can occur, affecting biodiversity, ecosystem functioning, and theavailability of ecosystem services. Fire and herbivory are two of the most widespread forces of disturbance which shape ecosystems globally. In temperate forest ecosystems, fire affects forest composition, which influences the diversity and resilience of ecosystems (chapters 1 and 2) and forest canopy structure, which is important to snowpack accumulation and the availability of water resources (chapters 3 and 4). In chapter one, the effects of …

Expanding Immediate Postpartum Contraceptive Options: South Carolina’S Medicaid Policy, Amy Mattison-Faye

Theses and Dissertations

Offering contraceptives is essential to allow women the opportunity to plan for pregnancy and help prevent mistimed or unintended pregnancy. Intrauterine devices and implants, also known as long-acting reversible contraceptives (LARC), are the most effective methods of contraception. South Carolina Medicaid in 2012 launched an innovative policy expanding contraceptive access and coverage for women delivering in hospitals to have the option to receive a LARC immediately postpartum. However, in order for this policy to be successful, it relies on the capacity of hospitals and providers to adopt and implement without assistance. Identifying the provisions necessary in order for successful policy …

Vietnamese Family Caregivers’ Adjustment Process To Their Caregiving Roles For Family Members With Dementia, Trang Nguyen

Theses and Dissertations

This study explores the psychological process that Vietnamese family members go through to adjust to the caregiving role for their relatives with dementia. Adopting constructivist grounded theory, 30 face-to-face, semi-structured interviews, including 10 follow-up interviews, were conducted with 20 Vietnamese primary family caregivers of relatives with dementia from the National Geriatric Hospital in Vietnam. The study results reveal that Vietnamese family caregivers held limited understanding of dementia. They used a mixed explanatory model, combining both folk (e.g., dementia as normal aging) and biomedical approaches (e.g., dementia as a brain-related disease) to explain causes of dementia. Family cohesion and responsibility are …

Examining Perceptions And Sensemaking Of Wellness Among African American Women Who Manifest The Archetype Of The Strong Black Woman, Donya D. Wallace

Theses and Dissertations

Furthering a strengths-based approach to mental health and wellness requires researchers to explore the role of cultural systems, sociohistorical factors and the intersectionality of race and gender as factors impacting wellness. To fill the existing gap in the literature describing perceptions of wellness through a cultural lens, I examined experiences of wellness among African American women who manifest the archetype of the Strong Black Woman. Working within the client’s perspective, Interpretative Phenomenological Analysis was employed to analyze data collected during semi-structured in-depth interviews and focus groups. I conducted the interviews to explored participant personal and social experiences with wellness. Super-ordinate …

Skeletal Muscle Recovery And Vibration, Garrett Collier Jones

Theses and Dissertations

In the past decade there has been a significant increase in focus on the effect upper body vibration (UBV) has on the recovery of skeletal muscle after exercise-induced muscle damage. Recovery can be defined and investigated using a wide variety of methods. This study used three different measurements to track muscle recovery over 7 days following an exercise muscle damage protocol and applied vibration to a mathematical model. A visual analog scale (VAS) was used to measure muscle pain, a strain gauge was used to obtain maximum voluntary isometric contraction (MVIC) strength measurements, and shear wave elastography (SWE) represented muscle …

Sensory Acceptability And Nutrient Stability In Micronutrient-Fortified Soymilk Prepared In Small-Scale Batch Processes, Dallin Max Hardy

Theses and Dissertations

Fortified and unfortified soymilk were produced from the same production batches for comparative evaluation. Fortification included a comprehensive array of micronutrients of interest to community and humanitarian nutrition programs. The effects of time after fortification prior to cooling, cooling method, and light or dark refrigerated storage on the stability of 5 vitamins (vitamin A, vitamin C, thiamine, riboflavin, and folate) were investigated for both fortified and unfortified soymilk. Significant vitamin C loss (6%) and mild vitamin A isomerization occurred while soymilk was hot immediately following fortification. Cooling bottled soymilk in an ambient water bath or ice water bath made no …

Effect Of Severe Economic Recession On The Psychological Distress: Evidence Of Modifying Effect Of Risky Behaviors And Insurance Status, Lumi Bakos

Theses and Dissertations

The investigation identified the effect of the 2007-2009 economic recession on the level of psychological distress (PD) as modified by engaging in risky behaviors and insurance status. The objective was to determine if engaging in risky behaviors and insurance status had an impact upon the level of psychological distress experienced during a recession; the timeframe for the study is 2007 representing pre-recession to beginning of recession year, to 2009 representing the recession year, to 2012-2013 representing post-recession years. The study involved the use of a nationwide non- institutionalized adult population, the Mental Health and Stigma optional module found in the …

Factors Associated With Advance Care Plans And End-Of-Life Care Choices Among Elderly Americans: An Analysis Of Health And Retirement Study Data, Agha Ajmal

Theses and Dissertations

Introduction

Advance care plans (ACP) allow people to plan for their end-of-life care before they become incompetent to make their treatment decisions. The umbrella term Advance Care Plans (ACP) includes the three most commonly used end-of-life care plans: Advance Care Planning Discussions (ACP discussions) and two advanced directives: living will and Durable Power of Attorney for Health Care (DPAHC). The ACP discussions are the verbal discussions about end-of-life plans, whereas the advance directives are written documents.

ACPs are distinct nuances of end-of-life care planning. ACP discussions address a wide array of end-of-life care issues, including terminal care, funeral, burial and …

The Intersections Of Health And Wealth: Socioeconomic Status, Frailty, And Mortality In Industrial England, Samantha Lee Yaussy

Theses and Dissertations

Socioeconomic status (SES) is considered one of the most powerful predictors of mortality today. However, studies of health in living populations and bioarchaeological studies of health in the past often oversimplify the connection between SES and mortality and overlook heterogeneity in frailty within a population and the potential for multiple types of marginalization to be layered within a single individual. This dissertation project uses skeletal samples to examine the interactions of SES, demographic characteristics (e.g., age and sex), exposure to physiological stressors, and mortality in the context of industrialization in 18th- and 19th-century England. Skeletal data from four industrial-era cemeteries …

Tenth-Grade Student–Participants’ Perceptions Of A Growth Mindset Curriculum: An Action Research Study, Jennifer Jo L. Dufort

Theses and Dissertations

The purpose of this action research study was to describe nine tenth-grade student-participants’ perceptions of a growth mindset curriculum based on the educational theory developed by Dweck (2006). The curriculum focused on the core aspects of Dweck’s (2006) theory: (a).understanding brain growth and neuroplasticity, (b) having a productive attitude about making mistakes and experiencing failure, and (c) expending effort and developing perseverance (Dweck, 2006). The teacher-researcher implemented the Growth Mindset Unit in a small high school in a coastal town in southern Maine during the teacher- researcher’s advisory class. The school has a proficiency-based grading system in which students benefit …

The Impact Of Intelligent Tutoring Software On Geometry Students, Simela Oueini

Theses and Dissertations

This purpose of this paper is to deepen the understanding for a problem of practice in the mathematics educators’ classroom of low retention of information thus leading to poor mathematics achievement. The identification of the problem of practice led to a development of a research focus examining the effects of using intelligent tutoring software in the mathematics classroom and the impact it has on mathematics achievement, student motivation as it relates to self-efficacy, student engagement and attitudes towards mathematics. Using a convergent mixed methods approach (Creswell, 2012), this paper elaborates on the research questions addressing “What effects does the integration …

Role Of Resources For Care In Improving Care Behaviors, Children’S Nutritional Status And Early Childhood Development In Low- And Middle-Income Countries, Sulochana Basnet

Theses and Dissertations

Poor child growth and suboptimal early childhood development are global health problems. Provision of appropriate care may help to achieve optimum child growth and development. Maternal resources for care such as education, knowledge, health, autonomy, reasonable workload, and social support may be needed to provide appropriate care behaviors, and improve children’s nutritional status, and early childhood development. The overall goal of this research was to understand the role of resources for care in improving care behaviors, child nutritional status, and early childhood development. The baseline Alive & Thrive household surveys from Bangladesh, Vietnam, and Ethiopia were used. We examined the …

Parenting And Child Self-Regulation As Mechanisms For The Relationship Of Household Food Insecurity With Child Dietary Behavior, Hoa Thi Mai Nguyen

Theses and Dissertations

Background: Food insecurity is both a nutritional problem and a stressful life experience of adults and children in households dealing with food shortage. Potential mechanisms of the associations between food insecurity and adverse outcomes in children’s health and development are through parenting and child self-regulation.

Objectives: We investigated parenting and child self-regulation as potential mechanisms for the relationship of food insecurity with child dietary behaviors with two specific aims. Specific aim 1 was to understand how food insecurity and its change over time relate to parenting in early childhood. Specific aim 2 was to understand the relationship of parenting in …

The Perspectives Of Emerging Adults With Hereditary Diffuse Gastric Cancer, Carrie Anderson

Theses and Dissertations

Individuals with hereditary diffuse gastric cancer (HDGC) caused by a CDH1 mutation have a high lifetime risk of developing gastric cancer. National guidelines recommend CDH1 carriers undergo a prophylactic total gastrectomy (PTG)— a surgery that greatly reduces the risk of developing gastric cancer but has significant comorbidities. This study explores the impact of a diagnosis of HDGC in the transitional life stage between the ages of 18-29 deemed “emerging adulthood.” We surveyed 21 CDH1 carriers and conducted semi-structured phone interviews with 6 CDH1 carriers between the ages of 18-29 to learn about their life experiences regarding education, career, relationships, and …

Nutrient Limitation Of Phytoplankton In Lake Wateree, South Carolina: Implications For Future Water Quality Management, Kara M. Clyburn

Theses and Dissertations

Cultural eutrophication is a primary contributor to phytoplankton production in freshwater lakes from excess anthropogenic nutrient inputs, and resulting impacts on water quality, aquatic ecosystems, human and animal health are increasing worldwide. Understanding the factors that limit phytoplankton growth is an important strategy for identifying and managing nutrient sources and successfully controlling the over- enrichment of nitrogen (N) and/or phosphorus (P) in freshwater lakes. The Redfield molecular ratio of carbon (C), N and P maintains that the C:N:P molar ratio is 106:16:1 when nutrients are not limiting, and the ecosystem is balanced. A N:P molar ratio > 20:1 tends to be …

Examining The Relationships Between Stress, Depressive Symptoms, And The Neighborhood Food Environment On Diet Quality Among Racially-Diverse Pregnant Women In South Carolina, Alycia K. Boutté

Theses and Dissertations

Background

Women’s diet quality during pregnancy often falls short of U.S. Dietary Guidelines and poor mental health and poor access to healthy food may be important barriers to improving diet quality during pregnancy. The purpose of this study was to 1) synthesize existing literature on the relationship between mental health and diet quality during pregnancy, 2) examine the relationship between mental health and diet quality in pregnancy, and 3) examine the relationship between healthy food density and diet quality in pregnancy.

Methods

For Aim 1 (systematic review), articles were obtained from five databases; study characteristics and findings were extracted and …

Amish Perspectives Of The Genetic Counseling Process, Brianna Teapole

Theses and Dissertations

The Amish are a population with a high concentration of genetic disorders who have informed our understanding of several genetic conditions. This culturally unique group has special need for genetic services. While clinics have been established to care for Amish individuals, such as the Community Health Clinic in Indiana, little research has been done on Amish perspectives of these services, specifically genetic counseling. Amish individuals who received genetic counseling from the Community Health Clinic were sent recruitment letters and a questionnaire via mail. The questionnaire consisted of demographic questions, a 7-item adapted Genetic Counseling Satisfaction Scale (GCSS), and open-response questions. …

Endolithic Microbial Carbon Cycling In East Antarctica, Natalie Tyler

Theses and Dissertations

Microbes adapt to inhospitable conditions by colonizing niches that protect them from severe environmental conditions, making them model organisms in the search for life on other planets. Endoliths are globally ubiquitous microbes that colonize structural cavities within rocks, which protect them from environmental stressors while maintaining access to nutrition and light sources. Despite harsh katabatic winds, extreme temperature fluctuations, harmful UV radiation and exposure to desiccation, endolithic communities have been observed in Antarctica. Previous studies have found viable and abundant microbial biomass through microscopy and the addition of isotopic labels. However, due to the slow metabolic activity of these microbes, …

Assessing Readiness For A Physical Activity Intervention In Positive Youth Development Afterschool Programs, Brittany Skiles Cook

Theses and Dissertations

Physical inactivity has been identified as a primary health threat to youth, and existing afterschool programs (ASP) are a promising context for implementing physical activity (PA) interventions. However, few PA interventions have been effective and generalizability of programs has been poor. Assessing organizational readiness during the testing of a PA intervention can help inform generalizability and sustainability. The R=MC2 heuristic separates readiness into motivation, innovation-specific capacity, and general capacity, each of which are further divided into subcomponents. The current multiple-case study pilot tests the feasibility and effectiveness/efficacy of a readiness assessment tool based on R=MC2 developed for the Connect through …

The Impact Of Student-Centered Coaching On The Implementation Of Project-Based Learning: An Action Research Study, Wanda Nicole Littlejohn

Theses and Dissertations

The present study describes a student-centered in-service that was implemented with four new teachers. The purpose of the study was to determine the level of confidence the four teachers felt after the coaching sessions. The study took place with teachers who teach in a high poverty school located in Greenville, South Carolina. The teacher-researcher is an Instructional Specialist at the school and she designed a project- based (PBL) learning unit with the teachers for ninth-grade students that was used in the coaching sessions in the fall of 2018. Data sources include: focus group interviews with the teachers; observations in the …