Digital Commons Network^™

Effects Of The In Ovo Injection Of Vitamin D3 Sources On The Hatchability, Performance, Breast Meat Yield, Small Intestine Morphology, And Immunity Of Ross 708 Broilers Subjected To Dietary Insufficiency And Pathogenic Agents, Seyed Abolghasem Fatemi

Theses and Dissertations

Effects of varying dosages (0.6 to 4.8 μg/egg) of vitamin D3 (D3) and 25-hydroxycholecalciferol (25OHD3), administrated by in ovo (amniotic) injection, on various embryonic and post-hatch physiological variables in Ross 708 broilers were investigated. The in ovo injection of 1.2 to 4.8 μg of both D3 and 25OHD3 increased serum 25OHD3 concentrations in broiler embryos in comparison to non-injected and diluent-injected control groups. Furthermore, the effects of 2.4 μg of D3 and 25OHD3 alone and in combination on the performance, meat yield and quality, small intestine morphology, and immunity of the broilers fed a diet restricted in calcium and phosphorous …

Evaluation Of Health, Production Parameters, Time To First Detected Estrus, And Behavior In Dairy Cows Treated With Pegbovigrastim, Mauricio Xavier Da Silva Oliveira

Theses and Dissertations

Pegbovigrastim injection (IMR) represents a new approach in overcoming mastitis. The objective of this study was to evaluate production parameters, overall health, time to first detected heat, and behavior of cows treated with IMR or a saline control. Study cows (n = 270) were blocked by parity group (multiparous or primiparous) and randomly assigned to control (CON, n = 144) or treatment (IMR, n = 126). Milk yield, fat, protein, lactose, solids nonfat percent, somatic cell count, and body condition, hygiene, and lameness were evaluated weekly. Animals were evaluated for metritis twice weekly via evaluation of rectal temperature, per rectum …

Kujdesi Infermieror Te Pacientët Me Infeksione Të Organeve Urinare, Blerinë Zeqiri

Theses and Dissertations

Qëllimi i këtij hulumtimi është që të konstatohet se sa janë të përhapura infeksionet e traktit urinar në rajonin e Ferizajit, shkaktarët, mosha dhe gjinia më e prekur .

Nga protokollet e repartit të urologjisë të Spitalit rajonal në Ferizaj rezultonë të jenë të regjistruar 172 pacientë të prekur në periudhën shtator 2018 – shtator 2019 ku gjinia më e prekur është gjinia femërore me 120 raste si dhe mosha më e prekur 45-74 vjeç.

Disa nga këshillat infermierore për ti evituar infeksionet urinare janë: të pihet shumë ujë, të shmangen pijet që mund të irritojnë fshikëzën, të mbahet higjena …

The Relationship Between Biofilm Production And Human Respiratory Cell Attachment And Invasion By Acinetobacter Baumannii, Rachel A. Pearson

Theses and Dissertations

Acinetobacter baumannii is an opportunistic gram-negative bacterial pathogen that causes many nosocomial infections in immunocompromised individuals. Common infections include catheter-associated urinary tract infections, ventilator-associated pneumonia, skin and soft tissue infections, and bloodstream infections that often lead to septicemia. Increasing multidrug resistance (MDR) in A. baumannii warrants new approaches to understanding its virulence mechanisms and pathogenicity. As a first step in infection, A. baumannii can attach to host cells, providing a surface for the bacteria to grow and perhaps facilitating biofilm formation and subsequent tissue invasion. In this study, we evaluated antibiotic resistance and characterized biofilm formation, attachment, invasion, and surface …

A Comparison Of Mmpi-2-Rf Profiles Of Outpatients With Reported Chronic Medical Conditions, Reported Disability, Or Psychological Ailments, Natalie Hicks

Theses and Dissertations

Past personality assessment research using MMPI instruments has examined their use in a variety of contexts, including in healthcare settings. The utility of the more recently developed Minnesota Multiphasic Personality Inventory-2 Restructured Form (MMPI-2- RF), however, has not been examined in these contexts to the same degree. The present study evaluated differences between MMPI-2-RF scores in a sample of 154 adult outpatient community mental health clients who (a) reported a preexisting physical condition in conjunction with psychological symptoms (n = 66), (b) were either in the process of applying for or were already receiving Social Security disability compensation (n = …

An Evidence Based Rationale For Making Tick - Borne Relapsing Fever A Nationally Notifiable Disease, Kyle M. Hatcher

Theses and Dissertations

Tick – borne relapsing fever (TBRF) is globally dispersed, and within the United States is found primarily in the mid – west, south - west, and north – west portions of the country. TBRF is a disease which causes patients to experience flu – like symptoms and is distinguished by multiple relapses of high fever which can cause individuals to be hospitalized multiple times over months. TBRF is caused by Borrelia spp. spirochetes and spread by Onthidoros spp. soft – shelled ticks. First diagnosed in the early 20th century, the disease has gone underdiagnosed and has attracted little attention for …

The Intergenerational Effects Of Adverse Childhood Experiences On Children’S Emergency Department Utilization And Depression And Anxiety In South Carolina, Eboni E. Haynes

Theses and Dissertations

Adult exposure to adverse childhood experiences (ACEs) is common in the U.S., with over half of adults reporting exposure to at least one ACE. Childhood trauma is associated with risk factors for premature death, disability, poor physical and mental health, and lower quality of life in adults. Traumatic experiences also influence parenting behaviors later in life, placing offspring at an increased risk of ACE exposure. Few studies have explored the intergenerational effects of ACEs on the health and well-being of offspring. This study sought to identify whether associations existed between caregiver ACE exposures and emergency department (ED) utilization for sick …

Study Of The Inflammatory And Fibrotic Pathology In The Gut Following Microcystin Exposure Under Conditions Of Non-Alcoholic Fatty Liver Disease., Sutapa Sarkar

Theses and Dissertations

Non-alcoholic fatty liver disease (NAFLD) has become a global pandemic with increased risks of chronic inflammation in obese and elderly population. It has become a major public health concern due to the unavailability of proper therapeutic approaches. NAFLD is a condition of the liver involving wide spectrum of events including accumulation of fat in the liver and inflammation, which can progress to a fibrotic and cirrhotic phenotype, often termed as non-alcoholic steatohepatitis (NASH). In this backdrop, exposure to environmental toxins from harmful algal blooms could prove detrimental to the overweight, obese or elderly population. NAFLD not only affects the liver …

Did Medicaid Expansion Under The Affordable Care Act Reduce The Likelihood That People Report Employment Status Changes Due To Health, U.S., 2009-2017, Songyuan Deng

Theses and Dissertations

Medicaid expansion of Affordable Care Act (ACA) extended coverage to low-income working adults. While Medicaid expansion led to increased healthcare use and national healthcare expenditures, current studies do not examine the effects of Medicaid expansion on health status from the perspective of social roles, for example, changes in employment status. This study use data from the Current Population Survey to examine the association between Medicaid expansion and the probability to attribute part-time work or not-in-labor- force to health issues among people with family annual income no more than 138 of Federal Poverty Level, with a difference-in-differences study design. We found …

Women’S Socio-Economic Empowerment And Uptake Of Hiv Testing In Ethiopia, Dawit Alemu

Theses and Dissertations

Introduction: Sub-Sahran Africa constitute two-thirds of all people living with HIV in the world. HIV infection rate is high in the continent with women comprising 56% of new HIV infections among adults 15 and older. Women 15 to 24 are the most affected constituting 66 % of new infections occurring among this age group. The purpose of this study was to examine how gender power relations between men and women affect health seeking behavior, particularly HIV testing, among Ethiopian women age15 to 49.

Methods: The Ethiopian Demographic and Health Survey (EDHS) from 2016 served as the data source for …

The Relationship Between The Electronic Health Record Patient Portal And Shared Decision Making, Gloria Esoimeme

Theses and Dissertations

Shared decision making (SDM) is a collaborative decision-making style where the patient and the physician are involved in the clinical decision-making process. The goal of this dissertation project was to examine the relationship between the patient portal of an electronic health record (EHR) and SDM.

The SDM process has three main components: information sharing, deliberation and decision making. Patients participate in SDM at varying levels: some patients may prefer to share information and deliberate but leave the final decision making to the provider while others prefer to participate in all the three components of SDM. The patient portal of an …

Resolving The Privacy Paradox: Bridging The Behavioral Intention Gap With Risk Communication Theory, Justin Chun Wah Wu

Theses and Dissertations

The advent of the Internet has led to vastly increased levels of data accessibility to both users and would-be attackers. The privacy paradox is an established phenomenon wherein users express concern about resultant security and privacy threats to their data, but nevertheless fail to enact the host of protective measures that have steadily become available. The precise nature of this phenomenon, however, is not a settled matter. Fortunately, risk communication theory, a discipline devoted to understanding the factors involved in risk-oriented decision-making and founded in years of empirical research in public health and disaster awareness domains, presents an opportunity to …

Age At Menarche, Measures Of The Midlife Gut Microbiome, And Cardiovascular Risk Factors, Yan Wang

Theses and Dissertations

Introduction Early menarche has been associated with greater risks of cardiovascular disease (CVD) and CVD-related mortality but the mechanisms remain unclear. We hypothesized that early menarche and CVD may share as a common cause, changes in the natural history of the gut microbiome. Methods We obtained data on 2,400 adult female twins from the TwinsUK registry. Participants reported their age at menarche retrospectively and underwent anthropometric and clinical laboratory measures in 1992-2014. They provided fecal samples in 2007-2012. Microbial DNA sequences represent the V4 region of the 16S rRNA gene. OTU-picking was done using open-reference strategy in QIIME and the …

Synthesizing Galactose Modified Polymeric Nanoparticles For Biofilm Inhibition Of Pseudomonas Aeruginosa, Tyler R. Flockton

Theses and Dissertations

Treating patients with antibiotics is becoming harder with the increase in antibiotic resistance. This is due to the widespread antibiotic use in clinical and agricultural settings. With antibiotic resistance outpacing new drugs making it to the market, developing new options to treat bacterial infections is and will be important. We created sugar modified nanoparticles to inhibit the biofilm formation of Pseudomonas aeruginosa.

P. aeruginosa is a gram-negative opportunistic pathogen that infects its host that has a compromised immune system. This makes it one of the most significant bacterial infection in hospitals. P. aeruginosa uses biofilms as an attack mechanism …

Characterization Of The Fungicidal Activity And Biochemical Impact Of Occidiofungin, A Novel Antifungal Compound Derived From Burkholderia Contaminans, Dayna Emrick

Theses and Dissertations

Fungal infections have a significant impact on the world population, with estimates of over 1.6 million deaths a year. One contributing factor is the increasing number of fungi resistant to the current clinical treatments, including the last approved family of antifungal compounds introduced into the market over a decade ago. This is driving the search for new antifungals with different biological targets. A new potential antifungal occidiofungin, is a cyclic glycolipopeptide isolated from the soil bacterium Burkholderia contaminans MS14 with a broad spectrum of activity against both human and plant pathogens. Kill kinetics demonstrated that this compound is fungicidal and …

Improvement Of Lead Abatement Programs Effectiveness In Peoria City/County Health Department Using Lean Six Sigma Methodologies, Songo Dede

Theses and Dissertations

The Focus of this mixed method research was the implementation of lean six sigma principles to improve productivity of outpatients’ programs where each case requires multiple scheduling, multiple visits to patients’ homes and multiple visits to the health department. The site is the Peoria City/County Health Department (PCCHD). The PCCHD is the delegate agency for Illinois Department of Public Health Childhood Lead Poisoning Prevention Program (EH). They are also a recipient of the Federal Lead-Based Paint Hazard Control (LHC) program from the Department of Housing and Urban Development (HUD). In line with their mission, they sought opportunities to review and …

The Silent Epidemic: Disparities And Obstacles In Obtaining Oral Care, Heather Hicks

Theses and Dissertations

American’s agree that dental health is important and vital to our overall wellbeing. However, not every American is achieving the same degree of oral health. Obstacles that American’s face include dental health disparities, limited access to affordable dental care, and limited access to dental insurance. This study examined how disease risk is shaped within the culture of oral health in Florida. This study examined those who provide dental care, those who cannot afford dental health insurance but earn too much money to qualify for Medicaid, and those with dental insurance. Hypotheses two and three were proven to be true, while …

Purification And Preliminary Characterization Of Zinc(Ii) Dependent Transcription Factor Adcr, Asm Saem

Theses and Dissertations

Transition metals are essential micronutrients for organisms. Excess zinc can be lethal to bacterial survival. Zinc homeostasis is crucial and is regulated by zinc uptake and efflux system. Streptococcus pneumoniae AdcR (Adhesin competence regulator) transcription factor is the member of MarR (multiple antibiotic resistance regulator) family proteins that suppress the zinc upregulation transporter. In the absence of zinc, AdcR has less affinity to bind DNA and uptake genes are expressed in order to transport zinc inside the cell. Streptococcus pneumoniae is a gram-positive human pathogen that is capable of colonizing in the human nasopharynx, especially in young children and leads …

Discovery Of Antifungal Metabolites In Maize Cob Via Liquid Chromatography-Mass Spectrometry, Jeremy Ray Winders

Theses and Dissertations

Maize (Zea mays L.) is a global food staple and is at risk from infection by the pathogenic fungus Aspergillus flavus L. The ubiquitous, soil-borne fungus causes ear rot of maize and produces the carcinogenic secondary metabolite known as aflatoxin. Aflatoxin B1 is the most potent carcinogenic mycotoxin known, causing hepatocellular carcinoma, along with many other serious health problems such as immunosuppression. Previous studies have shown that maize cob tissue plays an essential role in both facilitating and limiting the spread of the fungal pathogen A. flavus, however, little attention in the literature has been given to the cob. To …

Identification Of Protein Biomarkers For Differentiating Listeria Monocytogenes Genetic Lineage Iii, Basant Gomaa

Theses and Dissertations

Listeriamonocytogenes causes listeriosis and is one of the most virulent foodborne pathogens. Different subtyping techniques classified L. monocytogenes into four genetic lineages(I, II,III and IV)and seventeen serotypes. Most outbreaks of listeriosis are caused by lineage I. Lineage II is mostly associated with sporadic listeriosis, while Lineage III strains are typically lower risk for causing listeriosis. Listeriosis mainly affectselderly, immunosuppressed, children,andpregnant women causing fetal death, miscarriage, meningitis, encephalitis, and septicemia. Therefore, it is important to differentiate high-risk strains from low-risk strains, which will permit early and appropriate interventions. Our main goal in this current work is to detect candidate biomarkers unique …

Salem Belles, Succubi, And The Scarlet Letter: Transatlantic Witchcraft And Gothic Erotic Affect, Sylvia Cutler

Theses and Dissertations

In order to reconcile the absence of sexually deviant witch figures (succubae, demonic women, etc.) within the formation of American national literature in the nineteenth century with the fantastic elements found in European variations on the gothic, my thesis aims to demonstrate transatlantic variants of erotic signifiers attached to witch figures in nineteenth-century gothic fiction and mediums across national traditions. I will begin by tracing the transatlantic and historical impact of Heinrich Kramer and Jacob Sprenger’s Malleus Maleficarum—an early modern handbook of sorts used widely in witchcraft inquisitions—on Early American witch trials, specifically where its influence deviates from a sexualized …

Preparation, Functionalization, And/Or Characterization By X-Ray Photoelectron Spectroscopy Of Carbon Surfaces For Biosensors And Other Materials, Varun Jain

Theses and Dissertations

My dissertation is primarily divided into two parts. The first deals with the preparation, functionalization, and characterization of carbon surfaces prepared by direct current magnetron sputtering (DCMS) and high power impulse magnetron sputtering (HiPIMS) as substrates for bioarrays. Part two discusses applications of XPS peak fitting in surface chemical analysis. Chapter 1, the introduction, includes (i) a discussion of the construction of bioarrays and the preparation of sputtered surfaces, e.g., by DCMS and HiPIMS, and also functionalization (bioconjugate) chemistry with special emphasis on the importance of covalent functionalization of surfaces, and (ii) a discussion of the surface characterization techniques and …

Temperature Influence On Insecticide Resistance In Aedes Aegypti And Aedes Albopictus Mosquitoes From South Texas, Wendy Soledad Salinas

Theses and Dissertations

Aedes aegypti and Aedes albopictus are vectors for several emerging arboviruses including Zika, chikungunya and dengue. Both mosquitoes are found along the Rio Grande River in South Texas, along the border between Mexico and the United States of America. These mosquito species typically reside near human settlements. A preventative measure public health official use to help halt the spread of diseases is by controlling vector population with the use of insecticides, but as temperature vary, and with the constant exposure to commonly used insecticides, mosquitoes from South Texas may be developing a resistance to the insecticides. Resistance to insecticides may …

Bioaerosols Associated With Evaporative Cooler Use In Low-Income Homes In Semi-Arid Climates, Ashlin Elaine Cowger

Theses and Dissertations

Asthma is the leading chronic illness in children in the United States. Since children in the U.S. spend a majority of their time indoors there is an increased need to understand key sources of daily asthma triggers in the home. Bacterial endotoxin, dust mite allergens and β-D-glucan have been shown to be potent inducers of asthma attacks, and high levels of these allergens in homes can trigger attacks in those with asthma. We aim to better understand the risks to those with asthma that might be associated with evaporative cooler (EC) use in low-income homes. ECs are often promoted because …

Design And Synthesis Of Tlr2 And Tlr6 Heterodimer Ligands, A Triply Functionalized Α-Galcer Derivative For Identifying Proteins Involved In Glycolipid Trafficking, And The Disaccharide Of Staphylococcus Aureus Cp8 Towards A Self-Adjuvanting Vaccine, Sara Mayeth Mata

Theses and Dissertations

Toll like receptors (TLRs) are found on B cells, macrophages, monocytes, and dendritic cells, and these cells belong to the innate immune system that recognizes antigens and induces multiple cell responses through the release of cytokines. TLR1, TLR2 and TLR6 function as heterodimers, either as TLR1/TLR2 or TLR2/TLR6 to recognize lipopeptides. TLR1/2 dimer activation releases inflammatory cytokines, while TLR2/TLR6 dimer activation releases immunomodulatory cytokines. Based on the size of the binding pocket between TLR2 and TLR6, it was hypothesized that lipopeptides, such as FSL1, could be simplified while keeping overall activity. FSL1 is a lipopeptide first isolated from Mycoplasma salivarum …

Leveraging Geotagged Social Media To Monitor Spatial Behavior During Population Movements Triggered By Hurricanes, Yago Martín González

Theses and Dissertations

In a world of increased mobility and interconnectedness, the study of spatial behavior becomes more relevant than ever. However, multiple researchers have highlighted that the understanding of these dynamic processes has reached a bottleneck derived from the rigidity of traditional spatial behavior inquiry methods and the unavailability of trustworthy and relevant information. These difficulties are even more prominent during emergencies and disasters as these events often create scenarios where spatial behavior does not follow regular and logical patterns and where conventional mobility datasets are often skewed or not existent. Thus, many scholars working within the spatial behavior sub-discipline are pursuing …

United States Principals’ Involvement In Comprehensive School Physical Activity Programs: A Social-Ecological Perspective, Karie Lee Orendorff

Theses and Dissertations

Principal involvement is essential to the successful uptake of new school programs and initiatives. Recommendations and research underscore the key role of principals in supporting a comprehensive school physical activity program (CSPAP), which is a coordinated and synergistic approach to ensuring school-age accumulate the nationally recommended amounts of daily physical activity (PA), as well as develop the knowledge, skills and confidence for lifetime participation in PA. Little is known about the extent to which principals in the United States are involved in CSPAPs or about the factors that are associated with such involvement. The purpose of this dissertation was to …

Prevalence Trends Of Victimization Among High School Students By Race, Ethnicity, And Gender – Yrbss 2009-2017, Carlos Avalos

Theses and Dissertations

Introduction: Students who are victimized at school are more likely to report mental health, behavioral, and academic problems. Bullying and electronic bullying are types of victimization that are prevalent in US schools, with prevalence varying by race and ethnicity, gender, and age. Additionally, due to increases in bias-based harassment (such as being targeted due to race, ethnicity, or religious beliefs) in the country over the last few years, it is of interest to see how victimization behaviors in schools may have changed from 2015 to 2017.

Objective: To analyze trends of overall bullying, school bullying, electronic bullying, and other forms …

Medical, Anatomical, And Visual Transformations In The Japanese Woodblock Prints Of The Edo And Meiji Periods (1603 - 1912), Victoria Bennett

Theses and Dissertations

“Medical, Anatomical, and Visual Transformations in the Japanese Woodblock Prints of the Edo and Meiji Periods” first presents one of Japan’s lesser known genres of woodblock print. The history of the Edo and Meiji periods is overviewed, providing a contextual backdrop for the prints that are highlighted within the catalogue. Images from three sections: Anatomy, Disease, and Medical Practice are catalogued, supplying the viewer with new visual analysis and translation of prints. Each of these sections of print demonstrate the transformation of Japanese printmaking, from the Edo period to the Meiji, that accompanies the rapid transformation of Japanese culture during …

Social Networks, Social Support, And Contextual Factors That Affect Blood Glucose Control Among Individuals With Type 2 Diabetes Mellitus In Urban Ghana, Marian O. Botchway

Theses and Dissertations

This study used primary data from Kumasi, Ghana, to examine whether social networks, social support, diabetes-related stigma, religion, and traditional medicine affected blood glucose (HbA1c) control among adults with type 2 diabetes mellitus (T2DM). First, the study evaluated whether three social network characteristics (kin composition, household composition, and network density) were directly or indirectly (via social support) associated with HbA1c. Kin composition and household composition were significantly associated with social support. Neither network characteristics nor social support were associated with HbA1c, which suggests that social network characteristics may operate through mechanisms other than social support to affect HbA1c among study …