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Mindfulness, Moral Outrage, And The Climate Crisis: A Novel Approach Toward Motivating Pro-Environmental Behaviors, Erika Blair Jan 2024

Mindfulness, Moral Outrage, And The Climate Crisis: A Novel Approach Toward Motivating Pro-Environmental Behaviors, Erika Blair

Theses and Dissertations

The consequences of anthropogenic climate change are severe, continuously accelerating, and pose serious threats to the human and natural world. It is imperative to address the climate crisis from a psychosocial perspective and incite lasting, individual-level behavioral change. Various theoretical models have been adapted or developed to explain pro-environmental behaviors. However, the predictive powers of the most commonly used models have proven to be limited, and the underlying psychological processes of pro-environmental behavior constitute a significant gap in the literature. The present study identifies two psychological processes that show significant promise in motivating pro-environmental behaviors: moral outrage and mindfulness. Moral …


Mathematical Modeling Of Phage-Bacteria Population Dynamics, John Lawrence D. Palacios Jan 2024

Mathematical Modeling Of Phage-Bacteria Population Dynamics, John Lawrence D. Palacios

Theses and Dissertations

Bacteriophages are viruses that infect and replicate within bacteria. Lytic phages cause the bacterial cell to burst, killing the bacteria. These types of phages can be used to treat patients with antibiotic-resistant bacterial infections. As a step in developing successful treatment protocols, we aim to understand the population dynamics of phages and bacteria using an in vitro model. We model the dynamics using the Campbell model, which consists of a delay differential equation (DDE), as a base model. We extended the model by including the emergence of phage resistance. We then compared the DDE model with a parallel ordinary differential …


Black Teachers, Black Students, And Cultural Brokering: Leveraging Positionality To Strengthen Academic Identity, Shakasha L. Stevenson Jan 2024

Black Teachers, Black Students, And Cultural Brokering: Leveraging Positionality To Strengthen Academic Identity, Shakasha L. Stevenson

Theses and Dissertations

This study utilized a phenomenological photovoice approach to understand the lived experiences of veteran Black high school teachers. Black teachers are positioned to serve as cultural brokers to support the academic identity of Black students. The prevalence of symbolic violence in the Eurocentric curriculum and other curricular practices continues to hinder successful outcomes for Black students. The study leverages the experiences of Black teachers to understand how their positionalities influence their decision-making and pedagogical practices.

The literature review explored research on the social and political implications of Black education, Black identity development, cultural brokering, and academic identity. More specifically, the …


A Qualitative Descriptive Study Of The Perspectives Of Health Care Leaders Concerning The Implementation Of Telehealth, Gary Gerard Camille Jan 2024

A Qualitative Descriptive Study Of The Perspectives Of Health Care Leaders Concerning The Implementation Of Telehealth, Gary Gerard Camille

Theses and Dissertations

The purpose of this qualitative descriptive study was to explore how healthcare leaders on the east coast United States described the role of implementing, the outer setting, inner setting, individual characteristics, and the process when implementing telehealth in a patient-centered care environment in hospitals and healthcare facilities.

The study used a qualitative method with a descriptive design to capture the descriptions of the participant’s experience during the implementation of telehealth in a patient centered care environment in different health care facilities in east coast of the United States. Due to the onset of the Covid-19 pandemic, the interview sessions and …


Advanced Separations And Mass Spectrometry Data Acquisition Strategies To Improve Sensitivity And Throughput In Single-Cell Proteomics, Thy Truong Dec 2023

Advanced Separations And Mass Spectrometry Data Acquisition Strategies To Improve Sensitivity And Throughput In Single-Cell Proteomics, Thy Truong

Theses and Dissertations

Single Cell Proteomics (SCP) is an emerging discipline that contributes to a deeper understanding of individual cells' essential components. In biological systems, individual cells exhibit remarkable diversity, showcasing distinct proteomic profiles and functions. Mass Spectrometry (MS)-based techniques have become essential tools for exploring the proteomes of single cells with remarkable precision. While traditional bulk proteomics methods have been invaluable in revealing the overall protein composition of biological samples, they fall short in capturing the subtle nuances and heterogeneity among individual cells in a population. This limitation emphasizes the need for more targeted and detailed analyses to uncover the protein makeup …


Isolation And Characterization Of Nut Shell Proteins From Arachis Hypogea Linn. And Cocos Nucifera Linn. And Its Effect On Macrophage Activation To Treat Visceral Leishmaniasis, Suhatha S Dec 2023

Isolation And Characterization Of Nut Shell Proteins From Arachis Hypogea Linn. And Cocos Nucifera Linn. And Its Effect On Macrophage Activation To Treat Visceral Leishmaniasis, Suhatha S

Theses and Dissertations

Glycoproteins are among several immunomodulatory agents known to activate the innate immune system. Plant derived glycoproteins are a generous source of glycoproteins that could be utilized as cost effective preparations for therapeutics. Isolating glycoproteins from agricultural by- products with the intention to use them against Visceral Leishmaniasis (VL) was the focus in this doctoral study. The two nut shells, Arachis hypogea L. (Groundnut) and Cocos nucifera L. (Coconut), were used for the isolation of glycoprotein used in the study. Crude glycoproteins from the A. hypogea L. (AHP-C) were isolated and fractioned. AHP-F2 was identified as 28.37 kDa Mannose/Glucose binding lectin …


Development Of An Automated Delivery System To Apply Copper Sulfate Crystals Using Precision Dry Fertilizer Application Technology, Kevin Charles Wise Dec 2023

Development Of An Automated Delivery System To Apply Copper Sulfate Crystals Using Precision Dry Fertilizer Application Technology, Kevin Charles Wise

Theses and Dissertations

The digenetic trematode, Bolbophorus damnificus, poses a substantial threat to catfish aquaculture, causing significant economic losses. Infestations lead to suppressed feed consumption, secondary bacterial infections and poor production performance. Survey data reveals widespread infestation in the in the southeastern United States. Current control strategies involve the application of a concentrated copper sulfate solution to reduce snail populations which serve as the first intermediate host of the trematode life cycle. This study aimed to improve treatment efficacy by developing a granular copper sulfate application system. A modified Gandy fertilizer applicator, equipped with a programmable control system, demonstrated accurate distribution of copper …


The Impact Of Prior Pandemic Planning On Health Outcomes During The Covid-19 Pandemic: A Study Of Local Government Pandemic Planning In The United States, Karissa D. Bergene Dec 2023

The Impact Of Prior Pandemic Planning On Health Outcomes During The Covid-19 Pandemic: A Study Of Local Government Pandemic Planning In The United States, Karissa D. Bergene

Theses and Dissertations

In late 2019, scientists discovered a novel strain of coronavirus originating out of Wuhan, China. By January 2020, the United States (U.S.) saw its first positive case of coronavirus and the public was still unsure how serious of an epidemic this would be. By the time the World Health Organization declared the novel coronavirus disease (COVID-19) epidemic a “global pandemic” on March 11, 2020, world leaders, public health experts, scientists, and public administrators kicked into high gear to start serious pandemic response efforts. The public sector is typically the responsible authority for the preparedness, response, mitigation, and recovery of such …


The Migration Ecology Of North American Turkey Vultures Wintering In The Neotropics: Spatial And Population Dynamics, Adrián José Naveda-Rodríguez Dec 2023

The Migration Ecology Of North American Turkey Vultures Wintering In The Neotropics: Spatial And Population Dynamics, Adrián José Naveda-Rodríguez

Theses and Dissertations

The spatial and population dynamics of avian scavengers are poorly understood. This information is key for management and conservation interventions that guarantee long-term species conservation. My goal in this dissertation is to fill information gaps on the movement ecology of New World vultures using the Turkey Vulture (Cathartes aura) as a model species. I used a continental-wide satellite telemetry dataset to study the migration ecology, space-use, and demography of the three North American breeding populations of Turkey Vultures wintering in the Neotropics during a 17-year period. I found that primary productivity, but not weather, triggered Turkey Vulture migratory …


Opportunities For Mental Health Interventions In Rural Mississippi Communities During The Covid-19 Pandemic: A Quantitative Analysis, Brice Fortinberry Dec 2023

Opportunities For Mental Health Interventions In Rural Mississippi Communities During The Covid-19 Pandemic: A Quantitative Analysis, Brice Fortinberry

Theses and Dissertations

COVID-19 presented unique challenges for rural Mississippi communities including impacts on the mental health of rural individuals. This research study aimed to identify opportunities for mental health interventions to provide health promotion professionals with quantitative data on the accessibility and the likelihood of engagement with mental health-fostering behaviors. A secondary objective of this research was to categorize these behaviors within the constructs of the Social Ecological Model. Demographics for rural Mississippi communities were collected and displayed, and using multivariate analyses including Spearman’s correlation and a Mann-Whitney U test the correlation between mental health fostering behaviors and demographic factors was obtained. …


Increased Coding Potential Of Bovine Herpesvirus 1, Victoria Jefferson Dec 2023

Increased Coding Potential Of Bovine Herpesvirus 1, Victoria Jefferson

Theses and Dissertations

Bovine respiratory disease (BRD) costs the cattle industry millions of dollars in costs in treatment and loss every year in the United States. A significant pathogen often contributes to BRD is Bovine Herpesvirus 1 (BoHV-1), a double stranded DNA virus with the ability to establish latency in the trigeminal ganglia and neurons. Primary infection with BoHV-1 results in immunosuppression that increases the risk of secondary bacterial infection and pneumonia. Because herpesviruses infect their hosts for life and can be reactivated in times of stress, BoHV-1 can present a recurring risk of BRD. The following research aims to expand the knowledge …


Characterization Of Human Mobility From Cellular Data, Zaid Matloub Dec 2023

Characterization Of Human Mobility From Cellular Data, Zaid Matloub

Theses and Dissertations

This dissertation investigates human mobility patterns using crowd-sourced cellular network data from different Metropolitan Statistical Areas (MSAs) in the United States, spanning the Houston, New York-Newark, NJ City, and 13 other significant MSAs. By focusing on prominent spatial mobility parameters highlighted in existing literature, the study unveils consistent findings regarding the predictability of human mobility across diverse time scales and geographic regions. The research underscores the significance of selecting appropriate sampling thresholds based on the mobility parameters being examined, the size of the dataset, and available computational resources. Through a meticulous analysis, it emerges that while values such as mean …


Aedes Aegypti Host Preference On Canines Versus Human Volatile Skin Compounds, Melissa Bernadette Rosalez Dec 2023

Aedes Aegypti Host Preference On Canines Versus Human Volatile Skin Compounds, Melissa Bernadette Rosalez

Theses and Dissertations

It is critical to understand how Aedes aegypti mosquitoes detect hosts through cues such as volatile skin compounds. In South Texas, evidence suggests that this mosquito is showing a feeding preference for canines over humans. This shift may impact the transmission of Dirofilaria immitis, canine heart worms, in local dog populations. Our study is set to explore Ae. Aegypti attraction to hosts using canine and human volatile compounds. Volatile skin compounds will be collected using a volatile collection system. Compounds will be analyzed using gas chromatography/mass spectrometry. It is anticipated that the main volatile skin compounds amongst humans are nonanal, …


Growth Rates, Morphology, And Potential For Mariculture Of The Southern Population Of Crassostrea Virginica In The Lower Laguna Madre, Texas, Jerad Lee Fuelling Dec 2023

Growth Rates, Morphology, And Potential For Mariculture Of The Southern Population Of Crassostrea Virginica In The Lower Laguna Madre, Texas, Jerad Lee Fuelling

Theses and Dissertations

The Eastern Oyster also known as Crassostrea virginica, is an important resource here in the United States. Historically, this species has been overfished, poorly managed, and plagued by disease. Oyster mariculture is a growing industry here in the United States and is a sustainable solution to producing oysters. Texas has become the last coastal state to legalize oyster mariculture which means there is now a vast coastline with many unique bay systems that are open to this industry. One bay system that is particularly unique is the Lower Laguna Madre which is a hypersaline lagoon. Little is known about …


An Automatic Solver For Optimal Control Problems, Marcel Efren Benitez Dec 2023

An Automatic Solver For Optimal Control Problems, Marcel Efren Benitez

Theses and Dissertations

Optimal control theory is a study that is used to find a control for a dynamical system over a period of time such that a objection function is optimized. In this study we will be looking at optimal control problems for ordinary differential equations or ODEs and see that we can use an automatic solver using the forward-backward sweep using Matlab to solve for them from an 1 dimension to bounded cases and to nth dimension cases.


The Impacts Of Caregiving And Social Support On Stress For Multiple Sclerosis: A Study On Informal Caregivers, Jacqueline Mercado Dec 2023

The Impacts Of Caregiving And Social Support On Stress For Multiple Sclerosis: A Study On Informal Caregivers, Jacqueline Mercado

Theses and Dissertations

The purpose of the present quantitative study was to gain an increased understanding of the impacts of caregiving and social support on stress for unpaid informal caregivers of persons with Multiple Sclerosis. Caregiving for MS can be rewarding yet stressful. Informal caregivers are the primary source of ongoing home care for family members or friends with MS. Due to the complexity of care, caregivers are especially vulnerable to higher strain as they often feel unprepared for this role. This study examined perceived social support and demographic variables on caregivers' stress to gain insight into mediating caregiver psychosocial challenges. …


Monitoring Brain Region-Specific Control Of Protein Turnover And Concentration Using Proteomics, Rebecca Suzanne Burlett Nov 2023

Monitoring Brain Region-Specific Control Of Protein Turnover And Concentration Using Proteomics, Rebecca Suzanne Burlett

Theses and Dissertations

Regulation of metabolism is vital to health and lies at the core of many different diseases. The breakdown of metabolisms' regulation within the brain can lead to neurological disease like Alzheimer's Disease (AD). AD is known to affect brain regions responsible for memory and memory processing like the hippocampus and entorhinal cortex. The regulation of these regions' protein quality, synthesis, and degradation deviate from 'normal' or 'healthy' levels when AD is happening. It is known there is a breakdown of regulation in those regions; however, little is known about the specifics of regulation in healthy brains regions or how it …


The Relationship Between Parental Trauma History And Perceptions Regarding Their Child’S Healthcare And Utilization Of Healthcare Services, Krishna Patel Nov 2023

The Relationship Between Parental Trauma History And Perceptions Regarding Their Child’S Healthcare And Utilization Of Healthcare Services, Krishna Patel

Theses and Dissertations

Abstract

TITLE: The Relationship Between Parental Trauma History and Perceptions Regarding Their Child’s Healthcare and Utilization of Healthcare Services

Adverse child events (ACEs) have been associated with a number of physical and mental health problems and have also been linked to increased health care utilization. While parents who have an ACE history may tend to seek healthcare services for themselves, limited studies have examined the impact of their trauma history on seeking healthcare services for their child. Healthcare utilization may also depend on the parents’ level of health anxiety, as well as their anxiety about their child’s health status. This …


The Moderating Influence Of Individual Differences Between Perceived Organizational Support And Effort, Michael Schneider Oct 2023

The Moderating Influence Of Individual Differences Between Perceived Organizational Support And Effort, Michael Schneider

Theses and Dissertations

Perceive organizational support has many benefits for employees. The purpose of the present study was to determine if any of the Big Five personality traits moderate the relationship between perceived organizational support and work effort. One hundred and forty-four employees were surveyed on Prolific to identify their levels of perceived organizational support, work effort, and each of the Big Five traits. Perceived organizational support significantly predicted work effort. None of the Big Five traits significantly moderated the relationship in this primarily remote-working sample. These findings suggest that employees of all personality profiles respond similarly to support from their organizations.


Application Of Computational Tools To Identify Variations Associated With Peromyscus Dominant Spot, Zhenhua Shang Oct 2023

Application Of Computational Tools To Identify Variations Associated With Peromyscus Dominant Spot, Zhenhua Shang

Theses and Dissertations

Peromyscus are the most prevalent mammalian species in North America, and they're employed extensively in both laboratory and field studies. P. maniculatus and P. polionotus, the deer mouse and the old-field mouse, are closely related and can produce viable and fertile hybrid offspring. However, a comprehensive database of polymorphisms, particularly in those kept as living stocks and supplied to university researchers, is lacking. In chapter 2, we performed comparative genomic study on P. maniculatus and P. polionotus and used the polymorphic data to identify the range of genetic complexity that underlies physiological and behavioral differences between two species. We also …


The Intersectionality Of Rurality And Race On Covid-19 Vaccination Among Adults In The United States, Shiba Simon Bailey Oct 2023

The Intersectionality Of Rurality And Race On Covid-19 Vaccination Among Adults In The United States, Shiba Simon Bailey

Theses and Dissertations

Background Vaccination remains a cornerstone of public health, significantly contributing to the prevention and control of infectious diseases. During the COVID-19 pandemic, vaccine development was critical to prevent new SARS-Cov-2 infections. However, COVID-19 vaccination uptake among racial and ethnic minority populations and rural residents in the United States (US) lags behind their urban non-Hispanic White counterparts. Underlying causes of these disparities are unclear, but vaccine hesitancy, access to care barriers, and structural racism may be to blame. Such barriers may vary by residential urbanicity, leading to different racial/ethnic disparities in rural and urban America. Understanding the variations in vaccine uptake …


Antimicrobial Polymers And Small Molecules From Multicyclic Compounds And Engineering Of Sustainable Polymers, Leman Buzoglu Kurnaz Oct 2023

Antimicrobial Polymers And Small Molecules From Multicyclic Compounds And Engineering Of Sustainable Polymers, Leman Buzoglu Kurnaz

Theses and Dissertations

In this dissertation, the synthesis of polymers and small molecules from multicyclic compounds and the development of sustainable polymers from renewable feedstock were investigated. The antimicrobial biomaterials and sustainable polymers were characterized and their properties were discussed. In Chapter 1, the overall background and recent developments of antimicrobial biomaterials and their application were discussed. Later, sustainable polymers from renewable biomass and their synthesis methods were given. Afterward, the main research objectives of this doctoral research study were described. In Chapter 2, the synthesis of multiple charged small molecules from multicyclic compounds was discussed. These compounds were obtained by using various …


From Oceans To Public Health: Impact Of Climate Change And Socioecological Factors On Non-Cholera Vibrio Spp., Karlen Enid Correa Vélez Oct 2023

From Oceans To Public Health: Impact Of Climate Change And Socioecological Factors On Non-Cholera Vibrio Spp., Karlen Enid Correa Vélez

Theses and Dissertations

Climate change-induced stressors, such as temperature, salinity, pH, and wildfire, are contributing factors to the increase in frequency of Vibrio infections, altering Vibrio geographical constraints. At the same time, the expansion of the coastal population is resulting in increased input of treated municipal wastewater into areas that are also experiencing Vibrio proliferation. Given that increases in ocean temperature and sea level coupled with increases in human activity in coastal waters support greater Vibrio-human interactions, it is important to examine factors and mechanisms within this socio-ecological coupled system that may further strengthen this interaction. This study aimed to better understand the …


Replenishment Of Essential Natural Resources: An Assessment Of The Ability Of Freshwater Algae To Enhance Crop Quality And Soil Health, Lala Christina Ek Oct 2023

Replenishment Of Essential Natural Resources: An Assessment Of The Ability Of Freshwater Algae To Enhance Crop Quality And Soil Health, Lala Christina Ek

Theses and Dissertations

Disregard for soil, an essential natural resource, hinders global food production. Food insecurity is a major concern for both public health officials and environmental scientists due to soil quality decline, pollution, and climate change. Alternatives or targeted additions to chemical fertilizers can bolster soil quality, improve crop yields, lengthen crop shelf life, and mitigate environmental pollution. One potential alternative to chemical fertilizers is replacement of them with biological soil amendments, including algae, to enhance crop growth and improve soil health. Research was conducted at the University of South Carolina-Columbia campus garden to determine impacts of non-toxic freshwater algae on crop …


Correlates Of Immunization Timeliness In Three South Asian Countries: Secondary Analysis Of Demographic And Health Surveys, Tanzir Ahmed Shuvo Oct 2023

Correlates Of Immunization Timeliness In Three South Asian Countries: Secondary Analysis Of Demographic And Health Surveys, Tanzir Ahmed Shuvo

Theses and Dissertations

Despite the availability of effective vaccines, 1.5 million children under the age of 5 years die every year because of vaccine preventable diseases. Improvements in vaccine delivery infrastructure have resulted in relatively high coverage of vaccines, but many children are not receiving their vaccines on a timely basis. Timely administration of routine vaccines recommended by the Expanded Programme on Immunization (EPI) ensures maximum efficacy. It is vital to explore rates of vaccination timeliness and the correlates of timely vaccination among children to design targeted interventions for improving both coverage and timeliness. We conducted a secondary data analysis of the Demographic …


The Effect Of Antibiotics On Immune Cell Infiltration Of Colon In A Mouse Model Of Early Onset Colorectal Cancer, Valerie Hinsch Oct 2023

The Effect Of Antibiotics On Immune Cell Infiltration Of Colon In A Mouse Model Of Early Onset Colorectal Cancer, Valerie Hinsch

Theses and Dissertations

Early onset colorectal cancer (EOCRC) is an aggressive form of colorectal cancer diagnosed before the age of 50. While colorectal cancer cases in patients 50 years and older have been declining, EOCRC cases have been steadily increasing globally in the last few decades, and the cause is unknown. Many agents, called exposomes, have been associated with EOCRC based on their emergence and prevalence prior to and in parallel with the rise in EOCRC cases. Among these are antibiotics (Abx). Abx are indispensable in our fight against infectious diseases, however their overuse is becoming a global epidemic. They are prescribed globally, …


Weathering The Covid-19 Pandemic: A Study Examining How The Lived Experience Affected English Learners, Mary Kathryn Maxwell Oct 2023

Weathering The Covid-19 Pandemic: A Study Examining How The Lived Experience Affected English Learners, Mary Kathryn Maxwell

Theses and Dissertations

The COVID-19 pandemic profoundly impacted many students, especially the English learners who require specialized instruction and additional support to develop English language proficiency. This study examines how the pandemic created barriers that caused a decline in the academic achievement and engagement in the learning process of sixth-eighth grade English learners in an urban district in Ohio. In this mixed-methods study, using an explanatory sequential research design, quantitative data were collected through an online Likert survey while qualitative data were gathered from semi-structured interviews, artifacts, and researcher field notes. A total of 21 participants completed the survey and interviews. The merged …


The Utility Of Bayesian Predictive Models To Forecast Arboviruses In The United States Of America And Territories, Maggie Suzanne Jennave Mccarter Oct 2023

The Utility Of Bayesian Predictive Models To Forecast Arboviruses In The United States Of America And Territories, Maggie Suzanne Jennave Mccarter

Theses and Dissertations

Statistical models have been utilized to understand and forecast infectious diseases across the globe. However, these models have historically been difficult to access and interpret for non-specialist audiences. This dissertation focuses on one computationally efficient model fitting method, the integrated nested LaPlace approximation approach, to forecast three arboviruses in hopes of encouraging accessibility to statistical modelling. Such accessibility could provide areas who simultaneously are most susceptible to infection, and have the least resources, an invaluable tool for informing policy and prevention decisions. The resulting models included biological, land cover, and environmental factors and produced accurate forecasts of neuroinvasive West Nile …


Development Of An Antibiotic Resistance Breaker To Combat Staphylococcus Aureus Pathogenesis Skin Infections Ssis A Multidisciplinary, Gopalakrishnan T Mr Sep 2023

Development Of An Antibiotic Resistance Breaker To Combat Staphylococcus Aureus Pathogenesis Skin Infections Ssis A Multidisciplinary, Gopalakrishnan T Mr

Theses and Dissertations

Problem Statement: Staphylococcus aureus is a highly adaptable and tenacious pathogen known to cause a wide range of infections. The survival characteristics of the pathogen in different host niches are due to their ability to produce various pathogenic determinants. Although there lies the first line of treatment regimens with antibiotics, the pathogen defends at various levels to cause the waves of resistance - a silent pandemic “AMR”.

Notable strategies are through the protective layer, biofilm that enables the inter-/intra species communication (Quorum Sensing; QS) and emerges as a battleground to withstand host-immune response and antibiotic pressure. In parallel, several research …


“Já Muito Estropeadas”: Bodies And Landscapes Of Oppression In Rodolfo Teófilo’S A Fome, Mikaela Wood Aug 2023

“Já Muito Estropeadas”: Bodies And Landscapes Of Oppression In Rodolfo Teófilo’S A Fome, Mikaela Wood

Theses and Dissertations

This thesis article analyzes Rodolfo Teófilo's novel "A fome" through the lens of ecofeminism, exploring the representations of gender and nature in Brazilian literature. The novel, set during a devastating drought in the Northeast, follows Manuel de Freitas and his family as they seek relief in Ceará. While existing criticism has focused on the novel's use of nature and masculinity, the portrayal of female characters and the connection between gender and nature representations have been overlooked. Ecofeminist theory offers a critical perspective to understand these dynamics, revealing the devaluation of women and nature in favor of men and human beings …