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​​​Creating A Resident And Fellow Scholarly Activity Tracking Tool In A Large Academic Health System: A Dissertation In Practice​, Elyse Anne Wieszczecinski

Theses and Dissertations

Documenting and reviewing resident and fellow scholarly activity within a sponsoring institution can be a laborious task. With multiple lines of information coming from a wide variety of sources, this problem of practice implemented the Information Systems Success Model to help develop a database by which this information can be collected in a way that is efficient while maintaining the need for a user-friendly product. While other healthcare entities have also incorporated this model into their scholarly activity collection, these are still individual needs of the sponsoring institution and its constituents to consider when adapting the strategy. Using an improvement …

Adipokines Mediate Fat-To-Ovary Communication To Regulate Oogenesis, Adipocyte Size, And Lipid Storage In Drosophila Melanogaster, Chad Herbert Simmons

Theses and Dissertations

Humans have complex signaling pathways that allow them to store and expend energy based on nutritional quality and availability. Inter-organ signaling is used to communicate nutrient availability between organs based on nutritional needs and the rate of cellular division. Our main overarching question is to investigate how fat-derived signals affect adipocyte morphology and the maintenance of stem cells in the ovary. While signaling pathways, like insulin and mTOR, and some adipokines that are involved in inter-organ nutrient sensing have been identified, the exact nutrient reliant mechanisms of stem cell maintenance are not completely understood. Using Drosophila melanogaster as a model, …

Hearing The Difference: Just Intonation Techniques Utilizing Distortion Product Otoacoustic Emissions In Viola Performance, Calj Green Umezono

Theses and Dissertations

Difference tones, also known as distortion product otoacoustic emissions, are the result of active phenomena in the human cochlea during the conversion of sound waves into bioelectrical signals. Difference tones make it possible to explore alternative musical tuning systems beyond the twelve-tone, equally tempered regime. Musicians have investigated difference tones since the 18th Century in Euro-American musical contexts, but their application has so far been limited in scope. Advances in science, technology, and music theory from the late 19th Century through the early 21st Century have given present-day violists the opportunity to more fully understand the virtues of difference tones …

The Church As An Ecological And Cultural Anchor: Examining Its Role In Gifted Education, Advanced Academic Access, And Educational Equity, Matrissa Bennett

Theses and Dissertations

This action research study examines the role of the Black church as an ecological and cultural anchor in addressing the inequities of gifted education and expanding access to advanced academic opportunities for Black students. The study is grounded in Bronfenbrenner’s ecological systems theory, critical race theory, and racial and ethnical socialization, and it explores how the Black church can support student development, empower parental advocacy, and partner with schools to promote educational equity. Conducted at Mountain Valley Baptist Church in South Carolina, the interventions included student mentoring, goal setting sessions, academic enrichment, emotional support initiatives, a parent workshop, and a …

Eeg And Media Multitasking: Adhd As A Moderating Factor, Xiaoying Guo

Theses and Dissertations

Media use has become an integral part of everyday life. It has risen dramatically over the past century with the advent of television, computers, and digital platforms, and more recently, it has been characterized by individuals using multiple devices simultaneously (Bushman & Anderson, 2001; Nielsen Media Research, 1998; Rideout & Robb, 2019, 2021). Media multitasking (MMT) has been linked to cognitive control challenges and attentional difficulties. This study examined EEG workload (Fz theta/Pz alpha ratio), survey accuracy, and ADHD traits (ASRS v1.1) in 33 adult participants across baseline and single-versus dual-media conditions. Results indicated that mental workload was significantly higher …

Predictors Of Outpatient Follow-Up Attendance And Subsequent Psychiatric Readmission, Sandra J. Beltran

Theses and Dissertations

Psychiatric readmissions remain a persistent challenge in mental health care, often reflecting gaps in continuity of treatment following discharge. The Agency for Healthcare Research and Quality (2019) indicated that a key component in preventing inpatient readmission is adequate outpatient care following discharge. Moreover, early attendance in outpatient follow-up visits is associated with improved patient outcomes (Boston Medical Center, 2022). Various predictors are associated with engagement in outpatient services, such as age, medication compliance, and socioeconomic variables (Carson et al., 2014; Li et al., 2005; Marino et al., 2016; Stubbs et al., 2024).

The present study sought to determine whether psychiatric …

Parent Perspectives On Contemporary Adolescent Concerns, Allyson Worthy

Theses and Dissertations

Adolescence is a critical developmental period that marks the transition between childhood and adulthood. Psychopathology is known to emerge during this time, in which many internalizing and externalizing disorders have their onset. The assessment of adolescent psychopathology involves use of questionnaire measures to obtain perspectives from the adolescent themselves, their parents, and their teachers. Parents have been found to be especially important informants of adolescent functioning. With new challenges that arise for present-day adolescents (e.g., social media use), parents can provide insight into the different areas that need to be evaluated when assessing domains of contemporary adolescents’ development and psychopathology. …

Multilateral Organizations And Health Emergency Management During Crisis: The Case Study Of The World Health Organization During Covid-19 Pandemic, Aya Helmy Hamada

Theses and Dissertations

Multilateral organizations, such as the World Health Organization (WHO), play a key role in managing health emergencies during crises. During the COVID-19 pandemic, WHO achieved significant progress by supporting countries with technical assistance, guidelines, and essential resources. As well as providing technical guidance, sharing information, and coordinating among member states. This experience highlighted the importance of WHO in tackling global public health problems and showed how multilateral collaboration can help address complex challenges. Moreover, risk and crisis communication proved to be a critical part of WHO’s response, ensuring that clear and timely information reached the public and stakeholders. Despite these …

Exploring The Diversity And Biology Of Unique Giant Broad Host Range Bacteriophages In Natural Environments, Tannaz Mohammadi

Theses and Dissertations

Microbial interactions within the rhizosphere play a crucial role in shaping bacterial community diversity and function. To explore these dynamics, we isolated 21 bacterial strains from soil and plant root samples collected near Rocky Branch Creek on the University of South Carolina campus. Our findings revealed that a significant proportion of these bacteria are lysogenic for CbK-like phages belonging to the Dolichocephalovirinae subfamily. Additionally, we isolated free bacteriophages directly from the same soil samples and found them to be closely related to those harbored within lysogenic bacteria. Surprisingly, despite predictions of a narrow host range, most of these phages, both …

The Role Of Prelimbic Projections To The Rostromedial Tegmnetal Nucleus In Cue Discrimination, Emma Lane Carlson

Theses and Dissertations

Maladaptive decision-making, such as persistent reward seeking despite negative consequences, is a hallmark of substance use disorder (SUD) and related psychiatric conditions. These behaviors are thought to arise from impairments in aversive learning and disrupted neural signaling that normally supports behavioral inhibition. The prelimbic cortex (PL) plays a critical role in encoding cue–outcome associations and exerting top-down control over behavior, while the rostromedial tegmental nucleus (RMTg) serves as a GABAergic inhibitor of midbrain dopamine neurons in response to aversive stimuli. Although both structures have been implicated in reward and avoidance processes, little is known about how direct PL-RMTg projections contribute …

Behind The Gens: A Bioarchaeological Study Of Kinship Structure And Social Change In Iron Age Latium, Italy, Andrea Noemí Acosta Caballero

Theses and Dissertations

The cemetery of Osteria dell’Osa is the only completely published Iron Age cemetery from Latium. Its research legacy continues as dietary, mobility, and biological affinity patterns were reconstructed through carbon, nitrogen, oxygen, and strontium isotope analyses and biodistance analysis using bone and dental samples for this dissertation project. The main hypotheses tested are:

a) The diet of people buried at Osteria dell’Osa during the Iron Age likely consisted of mostly grains like wheat and barley, which may yield low carbon isotope signatures;

b) The protein consumption of the diet of people at Osteria dell’Osa was mainly composed of terrestrial protein …

A Comparative Analysis Of Two Symphonies By Robert Volkmann: Symphony No. 1 In D Minor, Op. 44, And Symphony No. 2 In B-Flat Major, Op. 53, Baha Lee

Theses and Dissertations

The 19th-century music scene boasts countless names, but some, like Robert Volkmann (1815–1883), have faded from the spotlight despite his prolific output as a composer, conductor, and educator. Volkmann’s music remains largely unknown and unperformed, waiting to be rediscovered. This lack of recognition provides a compelling opportunity to appreciate a talented composer and rekindle interest in his music. While scholarly inquiries into Volkmann are rare, delving into his major orchestral works, particularly his two symphonies, offers not only an understanding of his artistry but also a chance to revive interest in his captivating music.

Robert Volkmann composed only two symphonies …

Food Insecurity And Social Connection Of Nicaraguan Refugees And Asylum Seekers In Costa Rica: A Qualitative Study, Keren Herran

Theses and Dissertations

Background

Given the physical and mental health consequences of food insecurity, solutions should be evidence-based and seek to prioritize vulnerable populations. This qualitative study adds to limited literature on how refugees and asylum seekers use their social connections to mitigate food insecurity by investigating how Nicaraguan refugees and asylum seekers in Costa Rica foster social connections and use these connections to acquire and manage food.

Methods

In fall 2024, 35 in-depth semi-structured interviews were conducted in San José, Costa Rica. Participants were recruited through six migrant-serving nonprofit organizations. For study inclusion, participants had to: 1) be 18 or older; 2) …

Application Of Machine Learning For Vascular System Analysis, Alireza Bagheri Rajeoni

Theses and Dissertations

The analysis of vascular structures is critical for diagnosing, monitoring, and treating vascular diseases such as aneurysms, stenosis, and vascular calcification. Traditional methods often rely on manual interpretation of imaging data, which is time-consuming, subjective, and not scalable. This work explores the application of advanced machine learning techniques to automate and enhance vascular system analysis. Our contributions include achieving state-of-the-art accuracy in vascular segmentation, developing a machine learning pipeline to automatically quantify vascular calcification in peripheral arterial disease, and designing a multi-stage machine learning system for abdominal aortic aneurysm analysis that identifies aneurysm boundaries and estimates aneurysm volume in a …

Identifying And Understanding The Barriers To Sexual Health Information Seeking Experienced By Young Adults (Ages 18-26) Using Social Media, Alexander Nicolas Vera

Theses and Dissertations

This dissertation uses a qualitative, constructionist approach to examine the sociotechnical and cultural dynamics that shape digital sexual health-seeking practices of young adults. Guided by information practices and affordance theory, the research draws on semi-structured interviews and digital walkthroughs with 20 young adults (ages 18–26) from a convenience sample of young adults residing in South Carolina. Participants described how they use platforms like TikTok, Instagram, and Reddit not only to locate information but to assess its trustworthiness, inclusivity, and personal relevance in real time. Through in-depth accounts and screen-based demonstrations via digital walkthroughs, the study examines how participants engage in …

Recognizing The Unexpected: Deep Learning Across Complex Environments, Ge Song

Theses and Dissertations

Ensuring the security, trustworthiness, and operational integrity of modern autonomous and cyber-physical systems presents a critical challenge. While widely utilized in various engineering applications, such as intelligent transportation and industrial manufacturing, these systems require robust monitoring frameworks to identify unexpected anomalies in real-time, thereby maintaining operational safety and efficiency. This dissertation develops advanced deep learning methodologies for anomaly detection and health monitoring, with a particular emphasis on semisupervised reconstruction-based approaches that identify anomalies in complex environments using models trained only with normal operational patterns.

Building on this theme, the first study focuses on analyzing pedestrian behavior and detecting anomalies at …

Development Of A Strategy To Neutralize Ccl8 Activity And Ablate Ccl8 Cellular Targets, Bernardo Chavez

Theses and Dissertations

The chemokine CCL8 (monocyte chemoattractant protein-2) is a versatile signaling molecule involved in tumor progression, immune cell recruitment, and therapeutic resistance. Through activation of receptors including CCR1, CCR2B, and CCR5, CCL8 promotes leukocyte trafficking, epithelial–mesenchymal transition, and the establishment of immunosuppressive tumor microenvironments. In breast cancer and inflammatory diseases, elevated CCL8 levels correlate with poor clinical outcomes, making it a promising therapeutic target.

A strategy was developed to block CCL8 activity and selectively ablate CCL8 receptor expressing cells. A neutralizing monoclonal antibody, 1G3E5, was identified from a panel of murine candidates based on high affinity CCL8 binding. Sequencing revealed two …

Multi-Layer Decision Making For Long-Term Autonomous Mission Based On Dual Process Theory, Shruti Jadhav

Theses and Dissertations

Unmanned aerial vehicles (UAVs) are increasingly used in precision agriculture, where extended autonomous operation is required for monitoring, intervention, and field management. However, achieving long-term autonomy remains challenging due to battery constraints, environmental uncertainty, and the need to balance exploration with event-driven tasks. To address these challenges, a multi-layer decision-making framework inspired by Dual Process Theory (DPT) is developed. The framework combines reactive return-tobase strategies, exploratory navigation, and directional bias from prior missions, with a conflict-monitoring mechanism that adapts system behavior based on real-time conditions. The approach is implemented in a simulated agricultural grid environment, demonstrating improved adaptability and coverage …

A Qualitative Study Of Middle School Teachers’ Experiences Integrating Computer Coding Into Mathematics Classrooms, George William Austin Iii

Theses and Dissertations

As computers become more accessible in schools nationwide, teachers are embracing them to impact achievement positively (Brudno, 2013; Cetin, 2016). As a result, computer coding instruction has gained attention as a strategy for providing students with skills that will serve them both pre and post-graduation (Burke & Kafai, 2013; Yadav et al., 2016; Ng, 2017). Computer coding is the process of providing instructions for a computer to follow. In 2017, the South Carolina State Board of Education approved Computer Science and Digital Literacy standards for all K-8 public schools in the state of South Carolina (South Carolina Department of Education, …

Using Improvement Science To Study The Influence Of A Self-Regulatory Skills Intervention Program Within The Pre-Referral/Student Study Team Process, Abbie Sian-Stirone

Theses and Dissertations

The Dissertation in Practice (DiP) details a continuous improvement study utilizing Improvement Science and Plan-Do-Study-Act (PDSA) cycles to refine a school site's pre-referral/Student Study Team (SST) process. The need for this systemic refinement was driven by reported district-level equity concerns regarding the overrepresentation of Latinx students in special education. The study investigated the influence of a targeted Self-Regulatory Learning (SRL) Intervention Program, which leveraged an SRL Reflection Tool to teach explicit metacognitive and self-management strategies to Latinx students identified as at-risk of special education referral. Conducted in an urban public intermediate school, the research employed qualitative and quantitative data to …

Examining Special Education Administrators' Response To Due Process Complaints And Litigation Specific To Least Restrictive Environent, Melissa Jane Chiplis

Theses and Dissertations

Special education administrators have a complex and comprehensive role that requires them to be knowledgeable about special education law and the development of special education programming within their districts. The complexity of the role includes the managing of federal and state funds, allocating resources for the delivery of special education services, designing professional learning opportunities to support services providers with developing appropriate individualized education plans, and monitoring the effectiveness of special education programs. The outcome of these responsibilities is to ensure students with disabilities receive services in the least restrictive environment and to provide local education agency representatives with the …

Writers Helping Writers: The Power Of Peer Feedback In Student Writing, Heather Palmer

Theses and Dissertations

The purpose of this action research study was to improve students’ engagement with the writing process by focusing more intently on peer feedback. The study occurred in my sixth-grade classroom in an affluent suburb of a large U.S. city. As an insider to the setting, I used mixed methods to address a problem of practice, having noticed that students were not engaging in revision between their first and final drafts. Through the lens of social constructivism, I examined data collected through surveys, semi-structured interviews, and writing samples. Being both reviewers and recipients of feedback had positive yet distinct impacts on …

The Case For Using Student-Generated Goals To Cultivate Strong Readers, Heather Anne Wyman

Theses and Dissertations

This mixed-methods action research study explored how to motivate seventh-grade students to become stronger readers. I empowered my students by giving them the autonomy to set their own Lexile goals and develop plans to reach them, offering goal-setting lessons along with feedback and support. Students were motivated to meet the goals they created. Lexile assessment data from two benchmark periods enabled me to determine students’ growth, and survey and interview data helped me to determine their perceptions of their increase in self-efficacy and motivation to achieve. While most students did not meet their self-identified Lexile goals, most made academic progress, …

Unlocking The Power Of Connection: Engagement And Communication With Limited/ Non English Language Families, Melinda Hope Burnette

Theses and Dissertations

Family engagement can positively impact a student’s academic performance, attendance, literacy, and behavior at school (Bachman et al., 2021; Garbacz et al., 2018; Houri et al., 2019; Karge & Lansky, 2011; Robinson et al., 2022). However, there are several barriers to school-family communication, including additional responsibilities outside the school setting and socioeconomic factors. Parents and families who have limited/no English literacy skills face additional barriers to participation because of the lack of language support from schools in communicating events, providing access to language support at events, and parent perceptions of school acceptance (Arellanes et al., 2023; Perrigo et al., 2022; …

The Role Of Language Ideologies In Saudi Elementary English Education: Efl Teacher’S Perspectives And Experiences, Ghanem Saad S Alghuwainem

Theses and Dissertations

This dissertation examines how Saudi elementary English teachers understand and enact language ideologies in a period of rapid educational change and national reform. Using a comparative case study of five teachers in Al-Ahsa, the study triangulates semi-structured interviews, classroom audio recordings, and teaching materials to compare stated beliefs with observable practice. The analysis is guided by the theories of English hegemony and language and gender ideology, which together illuminate how global linguistic hierarchies are localized through teachers’ beliefs and practices. Findings reveal that teachers occupy an ideologically complex position as they balance the national push for English proficiency under Vision …

A Case Study Of A University Induction Program: Coaching Early Career Teachers, William Roy Blakeney Jr.

Theses and Dissertations

Abstract This is collective case study focuses on coaches working in a university-based induction program that supports early career teachers during their first three years of teaching. Interviews were conducted over a fall semester to document coaches’ perspectives on the critical incidents encountered by their coachees and the strategies they used to support resolution. New teacher attrition rates have contributed to a shortage of qualified teachers in the targeted schools and districts. This study was designed to explore a program that has yielded three-year teacher retention rates of over 90 percent for the past seven years. Six university induction program …

Too Much Of A Good Thing? Can Students Be Too Behaviorally Engaged, Rosemary Louise Odem

Theses and Dissertations

Student engagement in school is a key determinant of students’ academic success. Student engagement is commonly conceptualized as a meta construct comprised of three dimensions: emotional, cognitive, and behavioral engagement (Fredricks, 2015). Behavioral engagement, the focus of this study, is defined by positive conduct, involvement in learning and academic tasks, and participation in school-related activities (Fredricks et al., 2004). Some researchers have suggested that psychological strengths, like engagement, can be overused and result in maladaptive consequences (Niemiec, 2019; Oishi et al., 2007). This study addressed this notion using archival data from a sample of 422 students from one Southeastern US …

Erosion Of Bermuda Grass Covered Soils, Oru-Ntui Johnwatters Nkiri

Theses and Dissertations

Earthen embankments are the most common type of embankment due to the relatively low cost, simplicity, and material availability. However, they are also the most prone to erosion related failure, typically due to overtopping and piping. Research has been conducted to identify ways to control soil erosion and protect earthen embankments with different approaches such as addition of chemicals and biopolymer to the soil, installation of protective layering (geotextiles, concrete), increased soil compaction, and use of vegetation. This thesis considers the use of Bermuda Grass to increase resistance to erosion and protect embankments from failure during overtopping. Grass coverage and …

Multiscale Geometric Analysis In Endovascular Therapies: Ex Vivo, In Silico Approaches, Dima Hussein Ali Bani Hani

Theses and Dissertations

In this work, we address a persistent global challenge of vascular disease, specifically peripheral artery disease (PAD), and arteriovenous fistula (AVF) complications in patients with end-stage kidney disease (ESKD). The important role of vascular geometry in disease intervention plans and the development of endovascular therapeutic strategies (e.g., Drug-coated balloon (DCBs)) is critical in addressing these challenges.

This study evaluates the feasibility of co-delivery of paclitaxel (PTX) and valsartan (VAL) using urea-based coatings in DCB, analyzes the coating morphology and microstructural changes to improve therapeutic results. A computational finite element model was developed to complement experimental work, simulate tissue-coating interactions, compute …

Gut Microbiome Dynamics In Heart Failure And The Therapeutic Potential Of Nmeg-Cgrp, Kamryn Michael Gleason

Theses and Dissertations

Heart failure (HF) is increasingly recognized as a multisystem disease often linked to gut dysbiosis; however, its specific effects on gut microbial composition remain poorly understood. This study examined long-term changes in the gut microbiome in a murine HF model induced by transverse aortic constriction (TAC) and evaluated the effects of NMEG-CGRP. TAC mimics pressure overload-induced cardiac dysfunction, replicating key features of HF. CGRP, a neuropeptide with vasodilatory and cardioprotective effects, shows potential as a therapy for HF but is limited by rapid degradation. A stabilized analog, NMEG-CGRP, was used to assess its impact on cardiac and gastrointestinal health. Mice …