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The Relationship Between Traumatic Brain Injury And Disruptions In Heart Rate Variability And Heart Rate Variability Biofeedback: A Systematic Review, Leah D. Talbert Apr 2022

The Relationship Between Traumatic Brain Injury And Disruptions In Heart Rate Variability And Heart Rate Variability Biofeedback: A Systematic Review, Leah D. Talbert

Theses and Dissertations

Background: Traumatic brain injury is a significant public health problem. Heart rate variability is a potential modality to measure physiological dysfunction following traumatic brain injury to assist in determining recovery time and the relationship between traumatic brain injury severity and recovery. To date, a summary of the evidence across injury severities and the possible role of heart rate variability biofeedback in traumatic brain injury treatment is lacking but needed to determine potential clinical utility. Participants and Methods: We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Systematic literature searches on CINAHL, Embase, PsycINFO, SPORTDiscus, and MEDLINE …


Using The Community Of Practice Framework To Examine Informal Science Educators' Epistemological And Pedagogical Beliefs In Informal Science, Monique Andrea Lester Apr 2022

Using The Community Of Practice Framework To Examine Informal Science Educators' Epistemological And Pedagogical Beliefs In Informal Science, Monique Andrea Lester

Theses and Dissertations

When ranked and compared to students in other countries, students in the United States of America consistently rank below their peers in science knowledge. Among the many recommendations for increasing the science knowledge of students is a merge of informal science education (ISE) and public and private science classrooms. There is limited research focused on (1) the historical trends of research conducted in informal science education including the methodologies employed and pedagogical practices revealed and (2) the epistemological and pedagogical beliefs of formal science educators, who hold dual positions in the classroom and in an informal science setting. This dissertation …


Conflicting Cultures, Compromising Care: A Heuristic Inquiry Of Women Directors Of College Counseling Centers, Lindsay Noele Johnson Apr 2022

Conflicting Cultures, Compromising Care: A Heuristic Inquiry Of Women Directors Of College Counseling Centers, Lindsay Noele Johnson

Theses and Dissertations

The role that women leaders of college counseling centers have is unique; they must contend with the inherent social norms that women face in gendered organizations, in addition to negotiating the dichotomous, and often conflicting, leadership expectations of a care work division and a care-less upper administration. The purpose of this qualitative, heuristic, phenomenological study was to understand the lived experiences of women directors of college counseling centers. Moreover, this study sought to understand the lived experiences, beliefs, and actions of these directors how these experiences influenced, and continue to influence, their leadership pathway in a care-oriented division within the …


Physical Aspects Of Sexuality, Attachment, And Sexual Satisfaction, Chelsea Zollinger Allen Apr 2022

Physical Aspects Of Sexuality, Attachment, And Sexual Satisfaction, Chelsea Zollinger Allen

Theses and Dissertations

Healthy sexuality includes relational, emotional, and physical elements (Busby et al., 2021). However, there are gaps in what is known about the physical aspects of sexual relationships. Genital acceptance and physical sexual knowledge are two areas of physical relationships that may have an effect on the satisfaction of sexual relationships. Attachment, namely levels of anxious and avoidant attachment, is another factor that has been related to sexual relationships (Allsop et al., 2021; Bennett et al., 2019; Busby et al., 2020). Results from a dyadic sample of 515 couples who had been in a relationship for at least two years were …


Understanding How African American And Latino Males Choose A Major, And Its Influence On Retention And Persistence, Yosayra F. Solano Apr 2022

Understanding How African American And Latino Males Choose A Major, And Its Influence On Retention And Persistence, Yosayra F. Solano

Theses and Dissertations

The purpose of this qualitative study was to explore the process of selecting a college major for African American and Latino male students and whether these decisions influenced their sense of belonging and development of self-efficacy, as it relates to persistence and retention at a four-year public institution in the northeast region of the United States. Utilizing Harper's (2012) Anti-deficit Achievement Framework, this study used a Narrative Inquiry design to highlight the stories of six African American and Latino male students and their experiences with selecting a major. I collected data/field texts from two individual virtual interviews for this narrative …


A Vaccine Education Module For University Students: Vaccine Concerns And Knowledge Gained, Joslyn D. Wilson Apr 2022

A Vaccine Education Module For University Students: Vaccine Concerns And Knowledge Gained, Joslyn D. Wilson

Theses and Dissertations

Purpose: The purposes of this research are to evaluate the effectiveness of a vaccine education module (VEM) in 1) contributing to new vaccine knowledge of university freshmen; and 2) identifying common vaccine concerns of university freshmen before and after completing the VEM. Methods: A VEM, including information about vaccine-preventable diseases, benefits of vaccines, principles of community or herd immunity, and where to go to get vaccinated, was created for freshman students. Student vaccine concerns were identified using a pretest/posttest quasi-experimental design using an online questionnaire before and after completing the VEM. After the VEM, participants were also asked to identify …


Cherry Red Greenwashing: The Rhetoric Behind Corporate Recycling Narratives, Jessica Wallace Haws Apr 2022

Cherry Red Greenwashing: The Rhetoric Behind Corporate Recycling Narratives, Jessica Wallace Haws

Theses and Dissertations

As the public becomes more aware of environmental issues, corporations are pressed to consider and address the sustainability of their practices. Unwilling to drastically change business models, many corporations turn to greenwashing in an attempt to construct an environmentally friendly image while doing little to nothing to address sustainability issues. Using Kenneth Burke's work on identification and terministic screens, I analyze The Coca-Cola Company's "2020 World Without Waste Report" to illuminate how consumers come to believe in and identify with corporate greenwashing tactics. In line with Burke's theories related to identification, I argue that Coca-Cola's greenwashing strategies can be categorized …


Atg9a And Atg13 Cooperate To Drive Basal Autophagy, Daniel Morgan Poole Apr 2022

Atg9a And Atg13 Cooperate To Drive Basal Autophagy, Daniel Morgan Poole

Theses and Dissertations

Autophagy, as the name suggests, is a cellular process of self-eating in which cytoplasmic debris is engulfed by a double membrane vesicle dubbed the autophagosome and is ultimately degraded and recycled by proteases in the lysosome. The process is initiated by a group of core ATG proteins, including a multi-pass transmembrane protein called ATG9A. Although ATG9A has been shown to be essential for both stress induced and basal autophagy, its mechanism and interaction network remain largely illusive. Our current study employs BioID proteomics to identify a network of interactors, including regulators of membrane fusion and vesicle trafficking, such as TRAPP, …


Technology Use In Schizotypy Utilizing The Domains Of Technology Use Survey (Dotus), Devin Massaro Apr 2022

Technology Use In Schizotypy Utilizing The Domains Of Technology Use Survey (Dotus), Devin Massaro

Theses and Dissertations

The diathesis stress model for schizophrenia posits that genetics and prenatal factors confer vulnerability (diathesis) for mental illness which then may be activated through exposure to environmental stressors during life. One component of our contemporary environment involves technology use which has demonstrated risk and beneficial capabilities in regards to the schizophrenia spectrum. Using an online and in-person survey, this study aimed to elucidate the manner in which time spent on technology related to schizotypy, problematic technology use (PTU), and health behaviors in 227 undergraduate students (aged 18-30). We hypothesized that levels of schizotypy, as well as time spent on social …


"Do Not Blame Me": James Baldwin On White Christian Guilt And Racial Repentance, Celeste Lafollette Apr 2022

"Do Not Blame Me": James Baldwin On White Christian Guilt And Racial Repentance, Celeste Lafollette

Theses and Dissertations

James Baldwin, a Black American writer, contends that the root cause of America’s racial problem is not necessarily prejudice or hatred but guilt. In his essay, “White Man’s Guilt,” Baldwin says that most of the arguments white people use today against the reality of America’s racial problem can be reduced to a plea: “Do not blame me. I was not there. I did not do it” (Price 411). In many of his essays, Baldwin explores white America’s long history of guilt, denial, and justification, and he explains that many white Christians—in an attempt to avoid blame and protect their power, …


Psychological Distress Of Spousal Caregivers Of Older Adults: The Moderating Role Of Marital Quality, Avalon White Apr 2022

Psychological Distress Of Spousal Caregivers Of Older Adults: The Moderating Role Of Marital Quality, Avalon White

Theses and Dissertations

Caregiving, specifically caregiver burden, is commonly related to decreased psychological well-being. Conversely, marital quality is positively related to psychological well-being, though existing literature presents mixed findings as to whether or not a gender difference exists in this relationship. The current study examined the relationship between objective and subjective spousal caregiver burden and psychological distress with marital quality as a moderator. Gender differences in this relationship were also explored. 1,066 spousal caregivers from the National Study of Caregiving (NSOC) were used to estimate cross-sectional moderation models and plot significant interactions in Mplus. Results indicated a significant positive relationship between subjective caregiver …


Hybrid Suspension Tissue Engineering Of A 3d Alveolar Model For Lung And Vascular Disease Modeling, Jonard Corpuz Valdoz Apr 2022

Hybrid Suspension Tissue Engineering Of A 3d Alveolar Model For Lung And Vascular Disease Modeling, Jonard Corpuz Valdoz

Theses and Dissertations

Tissue engineering is a dichotomy of scaffold-based and scaffold-free cultures. Scaffold-based cultures form highly organotypic structures but with low uniformity and throughput. Conversely, scaffold-free cultures create consistently sized and shaped cell aggregates with limited spheroid-like structure and function, thus restricting their use for accurate disease modeling. We hypothesized that combining aspects of each culturing format, we would produce highly organotypic structures of consistent size and shape for use in pulmonary modeling. First, to improve on culture consistency and output, we created a novel easily scalable, minimalistic design for a micropatterned hydrogel dish that increases reliability and efficiency in 3D cell …


Perspectives About Food Safety In Diverse Low- And Middle-Income Countries, Sejla Isanovic Apr 2022

Perspectives About Food Safety In Diverse Low- And Middle-Income Countries, Sejla Isanovic

Theses and Dissertations

Concerns about unsafe food influence food choice, and consumption of unsafe foods increases morbidity and mortality, particularly in low- and middle-income countries. Actions to ensure safety of food are dominated by mitigation of biological and chemical hazards through supply-side risk management, disregarding individuals’ experiences and perspectives of food safety. We aimed to identify and categorize perspectives about food safety in five countries. Five Drivers of Food Choice projects provided transcripts from 17 focus groups discussions and 303 interviews in Kenya, Ghana, India, Guinea, and Vietnam. We analyzed transcripts using a priori and emergent codes. Individuals constructed meaning about food safety …


The Impact Of Framing On Natural Gas Pipeline Siting In Virginia, Ritvik Shukla Apr 2022

The Impact Of Framing On Natural Gas Pipeline Siting In Virginia, Ritvik Shukla

Theses and Dissertations

Natural gas has become a major share of energy consumption in the U.S. over the past two decades. This rise has resulted in considerable investment in the natural gas pipeline network so that the supply can be maximized. However, pipeline infrastructures, much like other fossil fuel energy infrastructures and activities, have an uneven distribution of benefits and costs across different regions. In regions where natural gas activities and infrastructure are being developed, local communities can become increasingly dependent on natural gas systems for stable revenue and employment. Such communities risk becoming “locked in” to carbon energy at a time when …


Higher Calling: A Qualitative Study Of The Lived Experiences Of Black Women Presidents Of 4-Year Colleges And Universities, Rushondra Janeé James Apr 2022

Higher Calling: A Qualitative Study Of The Lived Experiences Of Black Women Presidents Of 4-Year Colleges And Universities, Rushondra Janeé James

Theses and Dissertations

According to the National Center for Education Statistics (NCES), women are out earning men in the numbers of associate’s, bachelor’s, and master’s degrees awarded. When separated by race, Black women are the largest proportionally, representing 64 percent of bachelor’s degrees among Black women and men. Moreover, Black women account for 15 percent of all master’s degrees and 10 percent of earned doctoral degrees among all women. Given the most recent NCES statistics, the student body of degree granting institutions includes a significant number of Black women students. Conversely, about 9 percent of all college presidents and 3 percent of full-time …


Classification Of Acoustic Emission Data Into Load Steps Using An Artificial Neural Network, Allen Ross Apr 2022

Classification Of Acoustic Emission Data Into Load Steps Using An Artificial Neural Network, Allen Ross

Theses and Dissertations

The average age of bridges in South Carolina is approaching 40 years, very close to the 50-year service life. Almost 11% of the bridges in South Carolina are rated as structurally deficient, greater than the national average of 7.5% (South 2021). Health monitoring is the concept that in-situ sensors can continuously monitor civil structures and send real time signals of damage. This process allows for automation and could save time and money on the inspection and load rating of bridges. Health monitoring requires sensors that provide uninterrupted data without sacrificing the functionality of the bridge. A prime candidate for this …


The Relation Between Adhd Symptoms And Alcohol And Marijuana Use Outcomes Among College Students: The Mediating Role Of Experiential Avoidance, William Joshua Bradley Apr 2022

The Relation Between Adhd Symptoms And Alcohol And Marijuana Use Outcomes Among College Students: The Mediating Role Of Experiential Avoidance, William Joshua Bradley

Theses and Dissertations

Individuals with attention-deficit/hyperactivity disorder (ADHD) are at significantly greater risk for alcohol and marijuana misuse and abuse compared to their peers. College students with ADHD may be particularly vulnerable to problematic alcohol and marijuana use, given the widespread use and abuse of these substances by college students generally and liability associated with ADHD specifically. Experiential avoidance, or avoidance of unwanted thoughts, feelings, and other internal experiences, is positively associated with ADHD symptoms and substance use problems. However, it is unclear what role experiential avoidance plays in the relation between ADHD and alcohol and marijuana use. This study examined whether experiential …


“Zoom Degrees”: A Reflection On Education And Experience During The Covid-19 Pandemic Of The 2020s, Campbell Childers Apr 2022

“Zoom Degrees”: A Reflection On Education And Experience During The Covid-19 Pandemic Of The 2020s, Campbell Childers

Theses and Dissertations

This thesis is a self-reflection on time in the three-year Master of Fine Arts in Theater program at the University of South Carolina, during the 2020 rise of the Covid-19 Pandemic and the years after. It is a chronologically structured examination of two years of academic experiences, both prior to and during the pandemic, and one year of professionally application experience post-pandemic. The academics cover course experiences to production assignments and design opportunities, going into detail on the student’s process and thoughts at the time. The reflections on professional experience discuss the student’s future goals and how they have evolved …


Supervisory Allyship For University Custodial Staff, Daniel Colascione Apr 2022

Supervisory Allyship For University Custodial Staff, Daniel Colascione

Theses and Dissertations

This study will examine the lived experiences of campus custodians in search of creating an anti-racist workplace. Custodians will have the opportunity to share about their experiences involving racism and will be asked to explain their expectations of leadership in creating an anti-racist workplace. This study seeks to understand the expectations Black staff members have of their departmental and university level leadership to identify ways to narrow the gap between their expectations and the support they receive from those in positions capable of doing so.


“Whoz Ya People?”: Defining Lumbee Citizenship And Belonging In The 21St Century, Timothy Blake Hite Apr 2022

“Whoz Ya People?”: Defining Lumbee Citizenship And Belonging In The 21St Century, Timothy Blake Hite

Theses and Dissertations

The Lumbee Tribe of North Carolina is a state-recognized tribe with an estimated 60,000 citizens. From 2018-2020, the tribe closed their enrollment office so that the tribe could reexamine enrollment policies, particularly the criterion for appropriate contact with the tribal homeland. During this closure, the tribe was continuing its long journey for federal recognition, with a bill passing the U.S. House of Representatives and receiving support from then President Donald Trump and current President Joseph Biden. During the summer of 2021, I conducted ethnographic fieldwork with the tribe’s enrollment department, located in Pembroke, NC, to answer the question of how …


Epitaxial 4h-Sic Radiation Detectors For Harsh Environment Applications, Joshua W. Kleppinger Apr 2022

Epitaxial 4h-Sic Radiation Detectors For Harsh Environment Applications, Joshua W. Kleppinger

Theses and Dissertations

Epitaxial 4H-silicon carbide (4H-SiC) is an essential semiconductor material for the development of harsh environment radiation detectors due to its excellent electrical and thermal properties and resistance to radiation damage, opening the door for a wide variety of applications in NASA space missions, nuclear safeguards, and nuclear energy. However, the low atomic numbers of its constituent atoms Si (Z = 14) and C (Z = 6) make 4H-SiC nearly transparent to most neutrally charged radiation which can only be compensated using thicker active volumes.

In this dissertation, Ni/n-4H-SiC Schottky barrier diode (SBD) radiation detectors are fabricated for the first time …


Exploration Of The Role Of Neighborhood Residential Segregation By Race And Ethnicity In Obesity Risk Among School-Aged, Melissa L. Fair Apr 2022

Exploration Of The Role Of Neighborhood Residential Segregation By Race And Ethnicity In Obesity Risk Among School-Aged, Melissa L. Fair

Theses and Dissertations

Youth obesity prevalence remains high, despite decades of intervention. Grounded in the social ecological model, neighborhoods and schools are important settings in addressing the complex systems that influence obesity. Contributing to disparities, by race/ethnicity, Black and Hispanic youth are more likely to live in segregated neighborhoods and attend segregated schools, which are also more likely to have high rates of poverty and are less likely to have high quality nutrition and built environments. Leveraging data from local school district (district and state department of education) and national datasets (ACS, Childhood Opportunity Index 2.0), this study examined the associations between school …


Sex (Work) And The City: Sex Work In Columbia, South Carolina, 1860-1880, Presley Mckalyn Ramey Apr 2022

Sex (Work) And The City: Sex Work In Columbia, South Carolina, 1860-1880, Presley Mckalyn Ramey

Theses and Dissertations

Nineteenth-century sex work in the American south has long been neglected in sex work historiography. Formerly Confederate states have red-light districts rich in history, and stories of the South waiting to be told. The city of Columbia has great significance as the capital of the first southern state to secede from the Union, and this thesis acts as a local history of the city’s red-light district. Utilizing city ordinances, court cases, census records, city directories, probate records, and wills, the lives of Columbia’s sex workers and how they interacted with the growing city around them are brought to the forefront. …


S-Equol: A Novel Therapeutic For Hiv-1 Induced Gut Dysbiosis, Mason T. Rodriguez Apr 2022

S-Equol: A Novel Therapeutic For Hiv-1 Induced Gut Dysbiosis, Mason T. Rodriguez

Theses and Dissertations

HIV-1 infection affects approximately 38 million people around the world. The advent of cART has greatly improved the quality of life of infected individuals; however, roughly 50% of these individuals will still experience HIV-1 associated neurocognitive disorders (HAND). Additionally, the gut microbiome has been reported to be dysbiotic in HIV-1 infected individuals, regardless of adherence to cART. Current research has pointed to the gut-brain-microbiota axis as a potential target to treat both cognitive deficits and microbial changes. The present study investigated S-equol (SE) as a potential therapeutic for HAND by modulating the gut microbiome. The study included 21 HIV-1 Tg …


Engineering And Optimization Of An Aav Based Viral Vector To Limit The In-Vitro Expression Of Sars-Cov-2 Spike-Protein, Ronald Anderson Smithwick Apr 2022

Engineering And Optimization Of An Aav Based Viral Vector To Limit The In-Vitro Expression Of Sars-Cov-2 Spike-Protein, Ronald Anderson Smithwick

Theses and Dissertations

Severe Acute Respiratory Syndrome Corona Virus-2, also known as SARS-CoV-2, is a newly emerged respiratory viral pathogen. The outbreak of SARS-CoV-2 started in Wuhan, China, in late 2019 and rapidly transformed into a pandemic. Several vaccines have been developed and are available to the public on an unprecedented timeline, protecting individuals from a severe infection and saving precious lives. However, none of the vaccines can provide a sterile immunity, and the SARS-CoV-2 transmission cycle continues. Additionally, because of the mutation-prone RNA genome and immunological selection pressure, SARS-CoV-2 is rapidly mutating, especially the Spike(S) protein, and new viral strains are arising …


Three Essays In Behavioral Economics, Foteini Tzachrista Apr 2022

Three Essays In Behavioral Economics, Foteini Tzachrista

Theses and Dissertations

This dissertation includes three essays on behavioral economics with applications in health, strategic thinking, and labor.In the first essay titled ``The Effect of Nudging on the Utilization of Counseling Services and the Implications on College Student Involvement'', I examine the effect of nudging on the utilization of mental health services and the impact on college student involvement. To improve the utilization of mental health services for college students I designed and implemented an intervention promoting a pro-counseling social norm on campus. More specifically I sent campus-wide emails to inform students of the mental health services offered on campus. Randomly selected …


Female Reproductive Toxicity Of Harmful Algal Blooms-Produced Toxin Microcystin, Yingzheng Wang Apr 2022

Female Reproductive Toxicity Of Harmful Algal Blooms-Produced Toxin Microcystin, Yingzheng Wang

Theses and Dissertations

Harmful algal blooms (HABs) have become a global emerging environmental concern; however, its impact on women’s reproductive health is poorly understood. Microcystin-LR (MC-LR) is the most common and hazardous type of HAB toxin. Using both a chronic oral exposure mouse model and an acute exposure mouse model, I found that human-relevant exposure to MC-LR could compromise follicle ovulation via affecting follicle maturation. Both in vivo mouse exposure model and encapsulated in vitro follicle growth (eIVFG) model revealed that exposure to MC-LR did not affect follicle development, but significantly reduced the expression of some follicle maturation-related genes, such as Lhcgr and …


“That Was Denied Thee On Earth”: An Intersectional Bioarchaeology Of Institutionalized Euro-American Women Throughout 19Th And 20Th-Century America, Madeline Maria Atwell Apr 2022

“That Was Denied Thee On Earth”: An Intersectional Bioarchaeology Of Institutionalized Euro-American Women Throughout 19Th And 20Th-Century America, Madeline Maria Atwell

Theses and Dissertations

In the mid 19th-century, American state-supported insane asylums, later renamed state mental hospitals in the 20th-century, were constructed to house and humanely treat individuals perceived to be socially deviant or mentally and physically ill. Women were particularly vulnerable to undue institutionalization because of the prevailing patriarchal gender ideology within medical and colloquial spheres that contributed to the perception that they were biologically pathological. This dissertation interprets the findings of combined archival, historical, and osteological analysis from two U.S. skeletal collections: The Colorado State Insane Asylum (CSIA) Collection and the Hamann-Todd Human Osteological Collection (HT), to examine the embodied, physiological impact …


Molecular Architecture Of Cardiometabolic Responses To Regular Exercise, Jacob L. Barber Apr 2022

Molecular Architecture Of Cardiometabolic Responses To Regular Exercise, Jacob L. Barber

Theses and Dissertations

Background: To investigate the molecular mechanisms, determinants, and predictors of cardiometabolic responses to regular exercise, this dissertation had two primary aims: 1) Examine the molecular architecture of cardiometabolic responses to exercise training (unsupervised approach) and 2) Identify molecular signatures of responsiveness to regular exercise within clinically relevant lipoprotein traits (supervised approach).

Methodology: Multi-omics data (17,945 muscle transcripts, 4,979 proteins, 411 metabolites) from participants (n=647) who completed 20 weeks of endurance training as part of the HERITAGE Family Study was collected before and after training. We employed an unsupervised machine learning approach (Aim 1) to identify patterns of molecular responses to …


Longitudinal Relation Of Dietary Quality And Hemoglobin A1c In Youth And Young Adults With Diabetes, Hope Bercaw Apr 2022

Longitudinal Relation Of Dietary Quality And Hemoglobin A1c In Youth And Young Adults With Diabetes, Hope Bercaw

Theses and Dissertations

Background Hemoglobin A1c (HbA1c) is a clinical measure of glycemic control among people with diabetes and is associated with health outcomes such as cardiovascular disease. It is possible to decrease HbA1c by improving diet, but it is largely unknown which dietary components are most important in targeting glycemic control.

Objective This study aims to examine whether changes in diet quality across diabetes duration, assessed with the 2015-Healthy Eating Index (HEI), are associated with HbA1c in youth and young adults (YYA) with type 1 (T1D) and type 2 diabetes (T2D). Additionally, we aim to assess whether these relationships differ when dietary …