Digital Commons Network^™

Measuring Proteostasis Changes In Apolipoprotein E Mouse Models Using Quantitative And Kinetic Proteomic Methods, Ariel E.A. Denos

Theses and Dissertations

Alzheimer's Disease (AD) is a neurological disorder associated with brain mass loss and cognitive decline. It affects millions of elderly people and is currently uncurable. Since 1906, when the disease was first described, researchers have uncovered many components of AD pathology. However, it is now evident that curing Alzheimer's Disease will require intervention before the pathological onset of amyloid beta plaque deposition, tau neurofibrillary tangles, and associated neuronal loss. Studying AD from the perspective of early intervention requires special attention to small changes that may disrupt the normal processing of cells. Cells undergo a natural cycle of creation and destruction …

Family Religious Socialization Index: Development And Preliminary Validation, Kaelie Rene Crockett

Theses and Dissertations

A key area of interest for religious scholars is how religious beliefs are passed across generations, or religious socialization. To expand this field of study, a theoretically grounded, validated measure of this construct is needed. This article describes the development and validation of the Family Religious Socialization Index (FRSI), a multi-informant, multidimensional assessment of the processes through which parents socialize religion and faith in their children. Based on Social Cognitive Theory and through a rigorous development and validation process, three subscales were developed to represent the primary processes of religious socialization. The FRSI consists of two parallel scales, a parent …

Identifying The Brain Circuits Involved In Religious Obsessive-Compulsive Disorder, Kiana Bunnell

Theses and Dissertations

Obsessive-compulsive disorder (OCD) is an often-debilitating psychiatric disorder involving a pattern of obsessive thoughts and compensatory compulsions. Symptoms tend to be chronic, leading to substantial emotional burden and significant impairment across multiple domains of daily functioning. Previous research has identified some consistency in the brain regions implicated in OCD. In particular, cortico-striato-thalamo-cortical (CSTC) circuitry has been linked to behavioral features commonly observed in OCD. Moreover, some studies suggest that distinct patterns of brain activation and functional connectivity may be associated with different OCD symptom dimensions, though findings have not been consistent. One symptom dimension of OCD (scrupulosity) is characterized by …

Is “No Change” Really No Change?: A Qualitative Analysis Of Clients With “No Change” On Routine Outcome Monitoring Who Report Improving In Therapy, Audrey Louise Stewart Parker

Theses and Dissertations

Routine outcome monitoring (ROM), the practice of tracking client progress in therapy by administering regular questionnaires to assess functioning, has demonstrated a significant positive effect on psychotherapy outcomes, especially for clients are who not improving as expected. However, some researchers argue the symptom-based measures and outcome classification criteria commonly used in ROM may not represent a complete picture of client change. A recent body of mixed-methods research has investigated these ROM-determined outcome categories to gain insight into client experiences and whether the category and client perception of therapy outcome align. In this investigation, researchers have found significant variety within outcome …

Modifying Lta Zeolites For Reversible Hydrogen Sulfide Capture And Elucidating The Structure Of The Incorporated Metal And Sulfur Ions, Adeyemi D. Ojaide

Theses and Dissertations

Hydrogen sulfide (H2S) is a highly toxic and corrosive gas that poses significant environmental and industrial challenges, particularly within the wastewater treatment and oil and gas sectors. H2S leakage is among the deadliest industrial hazards, highlighting the urgent need for the development of highly efficient, non-corrosive adsorbents. This dissertation provides an in-depth examination of the use of metal-zeolites for H2S capture. We carefully investigate the impact of multiple divalent and one monovalent transition metals on LTA zeolites to optimize H2S removal. While Linde Type A (LTA) zeolites offer a robust structural framework for gas separation, a comprehensive understanding of how …

Behavioral Effects Of Novel Treatments For Pain Management Using Combinatorial Methods, Rohit Rajeev Nambiar

Theses and Dissertations

Pain, despite being an uncomfortable feeling to experience, is a necessary protective mechanism for the body1. Understanding that pain results from several different mechanisms within the body is important to discovering the optimal way to treat and manage a person’s pain. Modern medicine has seen numerous advancements in treating or managing acute and chronic pain, particularly with opioid drugs. However, these treatments come with potential side effects, including opioid use disorder (OUD) and fatal overdose. Finding new treatment methods, or improving existing methods, is crucial for patients with pain. This thesis explores two projects looking to develop safer analgesia using …

Surface-Modified Zinc Oxide Nanostructures For Ammonia Detection, Gowri Shonali N Ms

Theses and Dissertations

The escalating demand for sustainable gas sensors with low-ppm detection has driven research on surface-engineered nanomaterials for portable air-quality and health screening. This thesis focuses on the fabrication of nanostructured ZnO films as chemiresistive sensors for NH3 detection at RT. This study investigates surface modification using GO, rGO, g-C3N4, Ti3C2Tx; (Se, and Te) ink using a drop casting technique over DC-sputtered ZnO films. Surface modification plays a vital role by providing plenty of active sites, enhancing defective oxygen vacancy, facilitating charge transfer, and synergistic interaction between adsorbed oxygen species to enhance the sensing performance at RT. Among them trGO/ZnO hybrid …

Online Parent Group Intervention For Executive Function Skills For Autistic Children And Adolescents, Kathleen Clark

Theses and Dissertations

Executive functioning (EF) skills deficits are prevalent among children and adolescents with autism spectrum disorder (autism) that impacts their academic functioning, social relationships, and families' quality of life. This study aimed to explore an online parent group intervention, to test effectiveness of a 6-week parenting intervention on parenting stress and child's executive functioning (EF) among autism families in rural Utah with limited access to traditional intervention resources. The participants were eight parents from six families of children and adolescents (8-15 years) with clinical diagnosis of autism spectrum disorder and appropriate language abilities for their age. The parents participated in weekly …

A Coupled Reaction-Diffusion Model Of Promoting And Suppressing Interactions Among Cancer Hallmarks In Endometrial Cancer, Jeddy Bennett

Theses and Dissertations

Spatial transcriptomics enables the scoring of Cancer Hallmarks at a high resolution across a tissue biopsy, yet current analyses of these data remain largely descriptive, treating each spot as a static, independent observation. This thesis develops a coupled system of advection-diffusion-reaction partial differential equations to model the hallmark landscape as the steady-state solution of an underlying spatial process, and casts the recovery of its physical parameters as a PDE-constrained inverse problem. The framework is implemented in FEniCSx on tissue-specific finite element meshes derived from two endometrial cancer biopsies provided by the Huntsman Cancer Institute, with subdomains, boundary interfaces, and an …

Media Emotion Regulation And Executive Function In Childhood: Associations With Respiratory Sinus Arrhythmia, Lara M. Almeida

Theses and Dissertations

Media emotion regulation (MER), or the use of media to help children manage emotions, may influence children's development by shaping opportunities for practicing self-regulatory skills. Guided by the Dynamic, Relational, Ecological Approach to Media Effects Research (DREAMER) model, this study examined longitudinal associations between MER and executive functioning (EF) in early childhood and explored whether respiratory sinus arrhythmia (RSA), a physiological index of regulation, predicted developmental changes. Participants included 175 parent-child dyads assessed across two annual waves when children were approximately 4 and 5 years old. Structural equation modeling was used to test bidirectional associations between MER and EF while …

Physical Activity, Trauma, And Posttraumatic Stress: The Indirect Role Of Exercise Addiction, Anastasiia Rozumna

Theses and Dissertations

Exercise is often conceptualized as a protective factor for mental health, including for individuals exposed to trauma. However, less is known about whether exercise may relate to posttraumatic stress symptoms differently when it is accompanied by compulsive or addictive features. The present study examined whether volume and intensity of physical activity were associated with posttraumatic stress symptom severity indirectly through exercise addiction symptoms. This secondary cross-sectional analysis included 557 adults living in the United States who reported regular participation in sport or physical activity. Participants completed self-report measures of physical activity behavior, exercise addiction symptoms, trauma exposure, and posttraumatic stress …

A Systematic Review Of Posttraumatic Stress Disorder Among Hispanic Immigrants In The United States, Rashel Acireale

Theses and Dissertations

This study systematically reviews the literature on posttraumatic stress disorder (PTSD) among Hispanic immigrants in the United States, a population exposed to cumulative trauma across the migration process. Stressors may occur before, during, and after migration and include violence, family separation, dangerous travel conditions, discrimination, and fear of deportation. Despite these risks, findings on PTSD prevalence remain mixed, and Hispanic immigrants are underrepresented in clinical research and culturally informed interventions. This review examines sample representation, types and timing of trauma, PTSD measurement approaches, and the inclusion of cultural and contextual factors such as acculturation and immigration-related stress. It also evaluates …

College Sports Clubs: Engines Of Emotional And Social Development, Robert Robinson

Theses and Dissertations

This thesis examines the relationship between structured campus involvement and the development of campus connectedness among students at Rowan University. While the transition to university life is a critical period marked by social, emotional, and academic adjustments, this study highlights how sport clubs serve as a primary social anchor to facilitate successful integration. Utilizing a qualitative thematic analysis of focus group data across diverse campus organizations, this research clarifies how these spaces foster identity formation and resilience. Findings reveal that participation in sport clubs significantly enhances student wellbeing by providing support networks that mitigate early feelings of isolation. A key …

Depictions Of Girls With Adhd In Contemporary Picturebooks: A Critical Content Analysis, Madison Briann Smith

Theses and Dissertations

This study examines how girls with ADHD are depicted in contemporary picturebooks through the theoretical framework of critical disability studies (CDS). While research has increasingly explored disability representation in children's literature, depictions of girls with ADHD remain underexamined despite the ways in which ADHD manifests in female populations and the historical underdiagnosis of females with the condition. Using critical content analysis (CCA), six contemporary picturebooks featuring female protagonists with ADHD were analyzed for their visual and textual representations of neurodiversity. Findings were organized into two overarching themes: strength-based and deficit-based depictions. Strength-based portrayals emphasized creativity, identity formation through adult mentors, …

Recognition Of Autism Characteristics In Females: An Examination Of Stakeholders, Laurel Lyn Bishop

Theses and Dissertations

Autism is a neurodevelopmental communication disorder, characterized by differences in social communication, attention, interests, and sensory perception. Diagnostic criteria have historically applied to males, but clinical diagnostic criteria beginning in 2022 now include slight differences in traits comprising the female phenotype. Until recently, autistic females may be missed by the professional and education community or diagnosed later than males. Like their autistic male counterparts, they face an increased risk of suicidal ideation, but they also face more difficulties in peer relationships, academic problems, and increased anxiety and depressive symptoms, but may not get supports. School-age girls spend their days with …

Behavioral Indicators Of Stress In Wild Savanna-Dwelling Chimpanzees (Pan Troglodytes) In Fongoli, Senegal, Leah T. Williams

Theses and Dissertations

Stress influences health, reproduction, social relationships, and survival in primates. I identified behavioral indicators of stress in wild chimpanzees (Pan troglodytes) and determined whether coping strategies varied between behavioral contexts. Coping behavior differed significantly across contexts and behaviors, indicating that coping behaviors are strategically utilized in different contexts and provide insight into the emotional regulation of chimpanzees.

Extreme Heat And Its Impact On Public Transit Ridership In Nyc, Craig Denton

Theses and Dissertations

This thesis explores the connection between extreme heat events and public transit ridership patterns in New York City, with a particular emphasis on low-income communities. It investigates the intersection of socioeconomic factors and heat-related challenges, analyzing how extreme temperature periods influence overall transit use and why certain routes or neighborhoods experience greater declines in ridership during these events.

Utilizing existing literature, NYC-specific transit and climate datasets, and the broader context of transit equity, this research aims to inform strategies that strengthen climate resilience within urban transportation systems. The study’s findings are intended to support policy development and planning initiatives that …

Green Extractivism And The Discursive Legitimization Of Deep-Sea Mining In The Clarion-Clipperton Zone, Kaitlyn Maritan

Theses and Dissertations

This thesis critically examines deep-sea mining as an example of green extractivism, constructed through narratives of responsible mining practices. A content analysis assesses the discursive tactics of four actors in the emerging industry; how they collectively legitimize deep-sea mining and manage the contradictions of sustainability and extractivism.

The Introduction Of High-Speed Rail And Its Impact On Mode Choice The Case Of Morocco’S Al Boraq, Michael Stewart

Theses and Dissertations

Morocco's Al Boraq, Africa's first high-speed rail line, reshaped mode choice along the Casablanca-Tangier corridor. Drawing on ONCF ridership data, 234 rider surveys, and nine months of fieldwork, this ex-post assessment finds accelerated passenger growth, substantial induced demand, and mode shift from automobiles, informing Global South HSR development.

The Rpm-1/Phr Signaling Hub Modulates Tau-Induced Neurodegeneration Through Regulation Of Microtubule Stability And Mapk Pathways In C. Elegans, Xinxing Ding

Theses and Dissertations

Neurodegenerative diseases, including Alzheimer's disease and frontotemporal dementia, are characterized by the accumulation of pathological tau proteins and progressive neuronal loss. Although research regarding tau-mediated toxicity is extensive, the specific pathology that determine whether neurons maintain homeostasis or succumb to collapse under tau-induced stress remain incompletely elucidated. A central, yet still insufficiently understood, feature of these diseases is the disruption of the microtubule (MT) cytoskeleton . The PHR protein family is evolutionarily highly conserved; within this family, RPM-1 in C. elegans functions as an intracellular signaling hub that regulates axon development, synapse formation, axon termination, and various microtubule-associated processes. This …

The Influence Of Rainfall And Land Cover Change On Streamflow Variability In Eastern Florida Watersheds, Brynn Romberger

Theses and Dissertations

Streamflow in Florida watersheds is influenced by both land cover change and rainfall variability, but separating their contributions is difficult because both have changed over recent decades. This study evaluated rainfall trends and land cover change to determine which better explains flood and drought threshold exceedance across 27 USGS streamflow gauges within the St. Johns River Water Management District (SJRWMD) from 1985 to 2025. Streamflow was characterized using change-point, trend, and variability analyses with a six-threshold exceedance framework. Land cover was quantified using the National Land Cover Database (NLCD), rainfall characteristics were derived from the Analysis of Records for Calibration …

Helicopter Pilots’ Safety Behaviors: Identifying Factors That Affect Risk Perception Among Helicopter Pilots, Khaled J. Alzaabi

Theses and Dissertations

Helicopter operations frequently take place in complex, high-risk environments, where pilots continuously assess hazards and make critical decisions under pressure. Despite standardized procedures, regulations, and training designed to enhance safe operations, helicopter pilots may perceive risk differently when encountering similar flight situations. Understanding the factors that influence helicopter pilots’ perception of risk is essential for improving helicopter operation safety.

The purpose of this study was to investigate the effect of various factors on risk perception among helicopter pilots. Using an explanatory correlational design, the study assessed whether helicopter pilots’ demographics, flight experience, and affective domain factors explain differences in their …

Color-Coding: An Aid Or Hindrance In A Multi-Unmanned Aerial Vehicle Supervisory Control Task, Austin Daniel Wood

Theses and Dissertations

The purpose of the current study was to investigate the effect of coding types (i.e., alphanumeric coding, color-coding, and redundant color + alphanumeric coding) for vehicle identification and status information on pilots’ recognition performance, situational awareness (SA), and workload for a multi-vehicle operations ground control station (GCS) supervisory control task. With the aviation industry's push towards operators supervising and controlling multiple vehicles, it is pertinent to identify design features that support the capabilities and limitations of human operators. The current study employed a within-subjects, repeated-measures experimental design, in which a sample of 33 students with aviation experience performed three trials, …

Understanding The Correlation Between Prediction Performance And Trust In Ai Through Scenario-Based Tasks, Likhitha Kammara

Theses and Dissertations

Trust in artificial intelligence is commonly assessed through self-reported scales or behavioral reliance, yet behavioral reliance is retrospective and can only be observed after a decision has already been made. This thesis examines whether prediction accuracy — a user's ability to predict what an AI system will recommend before its output is revealed — can serve as a prospective correlate of trust in the same empirical sense as behavioral reliance. The study was conducted in two phases using scenario-based AI decision tasks across disaster response, healthcare, and infrastructure restoration contexts, employing a between-group design in which participants either predicted AI …

An Evaluation Of Staff Training To Teach Implementation Of Functional Analysis Of Inappropriate Mealtime Behavior, Lauren Marie Lightner

Theses and Dissertations

Avoidant/Restrictive Food Intake Disorder (ARFID) along with other feeding disorders are prevalent in both neurotypical children along with children diagnosed with autism spectrum disorder (ASD) and other developmental disabilities. Children with feeding challenges often exhibit inappropriate mealtime behavior (IMB) to avoid consuming non-preferred foods. It is pertinent to determine the function of IMB in order to create an efficacious treatment; one such assessment is the functional analysis (Iwata et al. 1982/1994). Iwata et al. (2000) taught students how to implement a functional analysis of self-injurious behavior using behavioral skills training. Since the assessment’s development, it has been extended to various …

Educator Perspectives Of Available Special Education Transition Programming Through High School Career And Technical Education Organizations For Female Students In Self-Contained Classrooms, Cassandra L. Aungst

Theses and Dissertations

The problem addressed in this study was that there is a lack of research regarding alignment between special education student transition assessments, transition goals, and transition programming and specifically those who identify as female students. While career readiness programs are accessible to all students, regardless of gender, female students in special education remain underrepresented in career and technical education programs. The purpose of this research was to review educational practices that influence female students with disabilities in relation to their individualized education plan transition goals and programming by addressing (a) educators’ perceptions, (b) systemic challenges, and (c) policy gaps influencing …

Online Mindfulness Training And Work-Related Outcomes: A Randomized Waitlist Controlled Trial, Conner Lee Deichman

Theses and Dissertations

Mindfulness-based interventions improve employee well-being, yet few studies have examined their impact on work-specific outcomes in private-sector samples. Online mindfulness programs offer a promising, accessible alternative to in-person training. This randomized waitlist-controlled trial evaluated the efficacy of Mindfulness for Humans (MfH), a fully online, self-directed 15-session program, on job satisfaction, burnout, work engagement, subjective well-being, and mindfulness skills among private-sector employees. Participants were randomly assigned to a training-first group or a waitlist-first group and completed measures at baseline, 30 days, and 60 days. Results showed significant improvements in job satisfaction, burnout, subjective well-being, and mindfulness following course participation. The training-first …

Discursive Consciousness And Pedagogical Reasoning Within Teacher Collaborative Inquiry In Rural Mexico, Nelly Yllen Charles Martinez

Theses and Dissertations

This study examines teacher collaborative learning within Matemáticas Equitativas (MATEQ), a school-based professional learning model designed to support equitable mathematics instruction through collaborative inquiry and peer observation. Drawing on Anthony Giddens' structure-agency theory, this research adopts an interpretive qualitative case study with discourse-oriented analysis to examine teachers' pedagogical reasoning by looking at manifestations of discursive consciousness--defined as the capacity to articulate and rationalize one's actions in discourse--during collaborative meetings. Findings show that both the interactional structures and collaborative resources embedded in MATEQ--in particular peer facilitated uses of observation rubrics--mediated teachers' discursive consciousness, strengthening the pedagogical reasoning shared within collaborative inquiry. …

Selective Factors Impacting Charter High School Enrollment, Nathan Marshall

Theses and Dissertations

This study examined factors influencing high school choice among Utah families, comparing parent priorities between charter and traditional public high schools. Using one-way ANOVA with Tukey honestly significant difference (HSD) post hoc comparisons, parental priorities were analyzed across personal, school community, and academic factors. Parents choosing traditional public high schools rated personal and school community factors significantly higher, emphasizing relationships and school climate, while charter high school parents rated academic factors significantly higher, favoring rigor and instructional quality. Charter parents' priorities were not uniform, however, but varied significantly by school model, suggesting that the charter-versus-traditional divide masks meaningful differences within …

From Anaerobic Digesters To The Human Gut: Ecological Responses Of Microbiomes To Environmental And Biological Perturbations, Maliea Annholden Nipko

Theses and Dissertations

Microbial communities regulate essential ecological and metabolic processes across both engineered and host-associated ecosystems. Although these systems differ substantially in composition and function, they are governed by common ecological principles including community succession, resilience, species interactions, and responses to environmental and biological perturbations. This dissertation investigates how perturbations influence microbiome structure, function, and stability through three complementary studies spanning anaerobic digestion and the human gut microbiome. First, the effects of an extremophilic biological pretreatment using Caldicellulosiruptor bescii were evaluated in industrial-scale anaerobic digesters treating dairy manure. High- temperature pretreatment substantially altered microbial community composition, with bacterial populations remaining metabolically active …