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Neuropsychological Profiles To Aid In Determining The Necessity For Neuroimaging Reviews: Providing Evidence For A Screener For Cerebrovascular Abnormalities, Kayla Blaire Miller
Neuropsychological Profiles To Aid In Determining The Necessity For Neuroimaging Reviews: Providing Evidence For A Screener For Cerebrovascular Abnormalities, Kayla Blaire Miller
Theses and Dissertations
This study aimed to provide evidence for a white matter abnormality (WMA) screener by investigating whether commonly used neuropsychological measures of executive functioning and processing speed have predictive power for identifying high WMA burden.
Participants were administered a brief neuropsychological evaluation by a doctoral student under the direct supervision of a board-certified clinical neuropsychologist and underwent an MRI scan. A neurologist rated each participant’s MRI results using the Fazekas scale. A total of 178 participants were included, divided into two groups based on their Fazekas rating: low WMA burden (46%) and high WMA burden (54%).
A confirmatory factor analysis indicated …
The Effect Of Resilience: Exploring The Link Between Depression And Cognitive Performance In A Memory Disorder Clinic Population, Amanda Capriglione
The Effect Of Resilience: Exploring The Link Between Depression And Cognitive Performance In A Memory Disorder Clinic Population, Amanda Capriglione
Theses and Dissertations
Introduction: Research has consistently shown that depressive symptoms are associated with cognitive impairments, namely in memory, attention, and executive functioning (for a review, see Rock et al., 2014), particularly in individuals with mild cognitive impairment (MCI). As MCI is often a precursor to dementia, understanding and addressing modifiable factors that influence this trajectory is essential for prevention and intervention efforts. Resilience, defined as the capacity to adapt positively to adversity, has been identified as a potential protective factor against age-related cognitive decline. Prior studies (e.g., Laird et al., 2019b; Miller et al., 2023) suggest that resilience buffers against the cognitive …
Occupational Exposure, Biomarker Profiles, And Safety Practices Among Egyptian Pesticide Factory Workers, Mireille M. Hanna
Occupational Exposure, Biomarker Profiles, And Safety Practices Among Egyptian Pesticide Factory Workers, Mireille M. Hanna
Theses and Dissertations
Background: Pesticide factory workers represent a critically understudied occupational population in Egypt, where existing literature has focused predominantly on agricultural field workers and spray teams, leaving the industrial manufacturing workforce virtually uncharacterized. Despite the potential for continuous, year-round, high-intensity mixed chemical exposure in factory settings, no contemporary comprehensive study has examined the multi-system health correlates of pesticide exposure among Egyptian factory workers.
Aim: This study aimed to assess the occupational health correlates of pesticide exposure among factory workers across neurological, hematological, hepatic, renal, endocrine, and reproductive outcomes, and to evaluate the role of exposure intensity, personal protective equipment use, safety …
How Does Foreign Direct Investment (Fdi) Impacts Egypt Economic Stability From The Specific Focus Of Exchange Rate And Economic Growth, Mohamed Medhat Merdan
How Does Foreign Direct Investment (Fdi) Impacts Egypt Economic Stability From The Specific Focus Of Exchange Rate And Economic Growth, Mohamed Medhat Merdan
Theses and Dissertations
This thesis examines the relationship between foreign direct investment (FDI) and economic dependency in Egypt, focusing on two channels through which such dependency may manifest: exchange rate volatility and economic growth. FDI has historically financed a disproportionately large share of Egypt's gross fixed capital formation relative to comparable regions, yet rigorous empirical research on its macroeconomic consequences within the Egyptian economy remains limited. Drawing on Dunning's eclectic (OLI) paradigm and Porter's diamond model, this study develops three hypotheses and tests them using an ARDL bounds testing approach applied to fifty-five years of annual data spanning 1970 to 2025.
The empirical …
Digital Maturity In The Administrative Prosecution In Egypt, Asmaa A. Hassan
Digital Maturity In The Administrative Prosecution In Egypt, Asmaa A. Hassan
Theses and Dissertations
The growing deployment of information and communication technologies in public service delivery, in general, and in the judiciary in particular, underscores the need for an assessment tool to evaluate digital maturity. Understanding digital maturity, a state in which an organization has completed digital development, helps diagnose the status quo, identify enablers, and address challenges, and consequently provide a roadmap for efficient improvements. This study aims to examine key factors affecting digital maturity within the Administrative Prosecution (AP) in Egypt, a pillar of the judicial authority and mandated to investigate financial and administrative violations committed by public servants. A mixed-methods approach …
Beyond The Legal Black Hole: Hyper-Legality, Deferral, And Detention In Northeast Syria, Grace T. Harmon
Beyond The Legal Black Hole: Hyper-Legality, Deferral, And Detention In Northeast Syria, Grace T. Harmon
Theses and Dissertations
This thesis examines the detention of suspected ISIS affiliates and their family members held in facilities administered by the Kurdish-led authorities in North-East Syria. Thousands of foreign nationals remain detained without trial, without repatriation, and in conditions widely criticized as inhumane. Existing scholarship and political discourse often describe these facilities as legal voids, limbo, or black holes where law has broken down or ceased to apply. This thesis challenges that characterization. Rather than existing outside the law, the facilities are governed through overlapping frameworks of international humanitarian law, international human rights law, counterterrorism security resolutions, and domestic laws. I argue …
Unearthing Potential: Impact Investors’ Perspectives On Egypt’S Social Enterprise Market, Yousef Hesham Shoukry
Unearthing Potential: Impact Investors’ Perspectives On Egypt’S Social Enterprise Market, Yousef Hesham Shoukry
Theses and Dissertations
This thesis examines impact investing in Egypt from the vantage point of the impact investors, revealing that Egypt's constraint is not the availability of capital but its direction, as the absence of legal recognition, coordinated intermediaries, and a shared impact-measurement standard keeps capital out of a market otherwise rich in social enterprise potential. The study employed a constructivist grounded theory approach, drawing on eleven semi-structured interviews with impact fund managers, ecosystem enablers, and public-sector policy advisors operating in or considering Egypt's social enterprise market. Data revealed that practitioners converge on the founding principles of impact investment (combined financial and social …
Enhancing User Engagement In Heritage Sites Through Interactive Digital Design: Development And Evaluation Of A Web-Based Application At The Qalawun Complex, Hend Bazeed
Theses and Dissertations
This study develops and evaluates a web-based interactive application for the Qalawun Complex in Cairo, a fourteenth-century Mamluk monument of significant tangible and intangible cultural heritage value, with the aim of enhancing visitor engagement beyond the passive observation that characterizes most heritage visits. The research is structured within an Asset-Design-Evaluate (ADE) framework and grounded in Radical Constructivism, Situated Learning theory, and the Design-Dynamics-Experience (DDE) framework, positioning the physical architecture of the site as the primary source of visitor knowledge through observation-based interaction tasks.
The application, titled "Qalawun's Treasure," comprises eight spatially anchored hotspots across the mausoleum, madrasa, and bimaristan of …
Nanoscale Water Confinement And Coordination-Driven Ion Transport In Eutectogel Electrolytes For Electrochemical Energy Storage Applications, Abdallah Akar
Theses and Dissertations
The rapid expansion of renewable energy systems, portable electronics, electric vehicles, and smart grid technologies has intensified the demand for advanced electrochemical energy storage devices capable of delivering high power density, long cycling life, operational safety, and environmental sustainability. Among these technologies, supercapacitors have attracted considerable attention because of their rapid charge-discharge capability, excellent cycling stability, and high-power performance. However, their relatively low energy density remains a critical limitation that restricts their broader practical application. Since the energy density of supercapacitors scales with the square of the operating voltage, expanding the electrochemical stability window of the electrolyte represents one of …
Egypt’S Accession To Brics: Hedging And Strategic Positioning In A Multipolar Order, Daria Konstantinova
Egypt’S Accession To Brics: Hedging And Strategic Positioning In A Multipolar Order, Daria Konstantinova
Theses and Dissertations
Amid Egypt’s longstanding, multifaceted cooperation with the U.S. and Western institutions, spanning political support, economic partnerships, and IMF/World Bank programs, 2024 BRICS expansion included Egypt as one of the new group’s members. This move might be explained by leadership strategic vision, domestic constraints, and geopolitical global and regional dynamics. This research explains the drivers behind Egypt’s accession to BRICS and the way this decision reflects Egypt’s strategic positioning in a changing global order, using agency-centered approach and the theoretical framework of strategic hedging.
While existing literature on BRICS expansion partially explains the reasons behind the new members’ accession and its …
Technology, Power, And Colonial Modernity: The Making Of The Egyptian Railways, Ahmed Mohamed Rahmy
Technology, Power, And Colonial Modernity: The Making Of The Egyptian Railways, Ahmed Mohamed Rahmy
Theses and Dissertations
This thesis examines Egyptian railways as a technology of power through which modern temporal order was gradually formed, reorganized, and contested. Focusing on the period from 1850 to 1920, it argues that railway infrastructure did more than facilitate mobility, economic exchange, and imperial administration: it reorganized the temporal relations through which social life was governed and experienced. Timetables, standardized schedules, fares, penalties, stations, and administrative procedures made punctuality, regularity, and measurable time appear as neutral requirements of life, while positioning existing ecological, agricultural, religious, and communal rhythms as signs of backwardness.
The thesis draws on British official correspondence, parliamentary debates, …
The Smuggled Body: Embodied Experiences Of Sudanese Displacement Along The Sudan–Egypt Corridor, Marielys Padua Soto
The Smuggled Body: Embodied Experiences Of Sudanese Displacement Along The Sudan–Egypt Corridor, Marielys Padua Soto
Theses and Dissertations
The outbreak of conflict in Sudan in April 2023 triggered one of the world's largest displacement crises, forcing millions of Sudanese civilians to flee toward neighboring countries, particularly Egypt. As legal pathways became increasingly restricted following Egypt's tightening of visa policies, many asylum seekers relied on migrant smuggling networks to reach safety. This thesis examines how restrictive mobility regimes are materially experienced through the body by introducing the concept of the smuggled body, defined as the body through which the physical, emotional, and social consequences of border control, irregular mobility, and forced displacement are lived. Drawing on embodiment theory, border …
How Can Egypt’S Technical And Vocational Education System Be Adapted To Improve The Employability Of Autistic Youth And Adults?, Miriam A. Menkarious
How Can Egypt’S Technical And Vocational Education System Be Adapted To Improve The Employability Of Autistic Youth And Adults?, Miriam A. Menkarious
Theses and Dissertations
This thesis provides original qualitative evidence on autism, employability, and TVET in an LMIC context, focusing on Egypt’s ongoing TVET reforms. The research investigated barriers and facilitators to employment for autistic youth and adults in Egypt, with a particular focus on technical and vocational education and training (TVET) as a potential pathway into work, and explored stakeholder perspectives on the potential, barriers, and conditions for adapting the Egyptian TVET system to improve their employability. Using the International Classification of Functioning, Disability, and Health (ICF) framework, this qualitative study relied on 20 semi-structured in-depth interviews with autistic youth and adults, parents …
Policy Coherence And Private Sector Development In Egypt: Aligning Governance Reforms With Development Finance, Shereef El Tanahi
Policy Coherence And Private Sector Development In Egypt: Aligning Governance Reforms With Development Finance, Shereef El Tanahi
Theses and Dissertations
Despite record volumes of development finance flowing into Egypt, the private sector, particularly its micro, small, and medium enterprises, has yet to experience the broad-based growth these investments were designed to catalyze. Between 2020 and 2025, international development partners committed more than 15.6 billion dollars to Egypt's private sector, yet private investment remains a modest share of the national economy, and most domestic firms continue to face severe barriers to credit.
This thesis argues that the answer lies not in the volume of capital mobilized, but in the coherence of the policies that govern how that capital reaches firms. The …
Simulation-Based Assessment Of Operational And Retrofit Solutions For Effluent Compliance Of A Capacity-Limited Oxidation Ditch Wwtp, Ahmed Sameh Harash
Simulation-Based Assessment Of Operational And Retrofit Solutions For Effluent Compliance Of A Capacity-Limited Oxidation Ditch Wwtp, Ahmed Sameh Harash
Theses and Dissertations
Oxidation-ditch wastewater treatment plants (WWTPs) across Egypt's Nile Delta are increasingly carrying hydraulic and organic loads beyond what they were designed for. This work can be considered pioneering as this work compared operational and structural retrofit alternatives for such a plant within a single verified simulation framework. The present study fills that gap by building a digital twin of the Qaha WWTP, a dual-train Carrousel oxidation ditch in Qalyubia Governorate, calibrated to a baseline flow of 7,420 m³/day in the SUMO24 platform (a third-generation, open-source wastewater treatment process simulation software) using the SUMO2c biokinetic model (a simplified variant of Activated …
Adjudicating Technology Facilitated Violence Against Women In Egypt: Between The Text And The Application, Eman E. Zidan
Adjudicating Technology Facilitated Violence Against Women In Egypt: Between The Text And The Application, Eman E. Zidan
Theses and Dissertations
Technology-facilitated violence against women (TFVAW) has surged on digital platforms, leading to a sharp rise in victimization rates among girls and women globally. Egypt’s pioneering cybercrime legislation, though comprehensive, remains gender-neutral and inadequate in judicial application. Community perceptions reveal systemic gaps that erode public trust and fuel demands for specialized protections. This study analyzes Egyptian judicial responses to TFVAW cases through comparative jurisprudence with jurisdictions that feature gender-specific norms. Findings demonstrate that textual provisions alone fail to arrest this escalating phenomenon, underscoring the need for integrated reforms: tailored legislation, heightened awareness campaigns, and collaborative education on rights, duties, and societal …
Grievability Of The Abject As Narrated By Exiles, Sylvia Azmy
Grievability Of The Abject As Narrated By Exiles, Sylvia Azmy
Theses and Dissertations
This thesis analyzes two novels: Inaam Kachachi’s Sawaqi al-Qulub (2005) and Shady Lewis’s ʿAla Khatt Grinitsh (2019), to understand the relationships between figures of migration, as the exile narrates his encounters with refugees. It uses Julia Kristeva’s Powers of Horror: An Essay on Abjection (1980) and Judith Butler’s Frames of War: When Is Life Grievable? (2009) as theoretical frameworks to examine the deaths of refugees and their corpses (utmost of abjection) in the two novels. Scholars have argued that the literature of forced migration is becoming more inclusive than migration narratives, a term that has focused on student travelers, exilic …
Sustainable – Low-Cost - Upgrade Of Activated Sludge Process For Nitrogen And Phosphorus (N&P) Removal From Wastewater, Abanoub N. Basta
Sustainable – Low-Cost - Upgrade Of Activated Sludge Process For Nitrogen And Phosphorus (N&P) Removal From Wastewater, Abanoub N. Basta
Theses and Dissertations
Many municipal wastewater treatment plants (WWTPs) in developing countries were designed primarily for organic matter and suspended solids removal and therefore face increasing difficulty in meeting modern nitrogen (N) and phosphorus (P) discharge requirements. Conventional biological nutrient removal upgrades commonly require additional reactor volume, recirculation systems, aeration energy, and capital investment. Accordingly, sustainable retrofit strategies that improve nutrient removal within existing treatment footprints are increasingly needed, particularly in water-scarce and land-constrained regions.
This study investigated the integration of water hyacinth (Eichhornia crassipes) into the aeration stage of an activated sludge process as a hybrid nature-based enhancement for nitrogen and phosphorus …
A Comparative Study: Force Majeure And The Theory Of Unforeseen Circumstances Across Different Jurisdictions In The Middle East, Omar Hamed Sawan
A Comparative Study: Force Majeure And The Theory Of Unforeseen Circumstances Across Different Jurisdictions In The Middle East, Omar Hamed Sawan
Theses and Dissertations
The motivation behind this study stems from recent global disruption events that impact construction projects worldwide. These events vary across a wide spectrum, whether they are political events such as the Russo-Ukraine war or the war in the Middle East, economic events such as inflation or currency devaluations; or environmental events such as climate change and the emergence of public health crises like the Covid-19 pandemic. These series of events underscore the growing importance of understanding how the different legal frameworks address unforeseeable events in the construction industry. In this context, force majeure and the theory of unforeseen circumstances (also …
Knowledge, Attitudes, And Practices (Kap) Of Parents Regarding The Prevention And Control Of Childhood Iron Deficiency Anemia In Egypt: A Cross-Sectional Study, Omnia Soliman
Theses and Dissertations
Childhood Iron Deficiency Anemia (IDA) remains a major public health challenge in Egypt, where its persistently high and rising prevalence carries substantial consequences for child growth, cognitive development, immunity, and long-term health outcomes. Globally, approximately 40% of children aged 6–59 months are affected by anemia (World Health Organization, 2025), and Egypt mirrors this burden, with national data showing a worsening trend in recent years. In Egypt, national strategies have traditionally focused on biomedical interventions such as iron supplementation and food fortification, while less attention has been directed toward behavioral and household-level determinants, particularly parental knowledge, attitudes, and practices (KAP) related …
Study Of Fast Switching Metastable-State Photoacids And Controlled Drug Release From Polycaprolactone (Pcl) Vascular Scaffold, Rana Salman Abbood Abbood
Study Of Fast Switching Metastable-State Photoacids And Controlled Drug Release From Polycaprolactone (Pcl) Vascular Scaffold, Rana Salman Abbood Abbood
Theses and Dissertations
Metastable-state photoacid (mPAH) has become a common tool for controlling and driving chemical processes with light. mPAHs with fast reverse reactions are desirable for precise temporal control or generating quick pulses of proton concentration. In this work, different approaches towards fast reversing mPAHs are studied. Experimental and computational results showed that stabilizing the charge–transfer intermediate is an effective way to increase the rate. A novel mPAH with a reverse reaction ≈500 times faster than the most widely used mPAH in methanol has been developed. Another water-soluble mPAH exhibited a reverse reaction with a rate constant of 7.8 s−1, the fastest …
Comparative Performance Of Physiological Vital-Sign Forecasting Under Random And Patient-Wise Splitting Using Deep Learning, Lavanya Vasavi Chittem Reddy
Comparative Performance Of Physiological Vital-Sign Forecasting Under Random And Patient-Wise Splitting Using Deep Learning, Lavanya Vasavi Chittem Reddy
Theses and Dissertations
Physiological vital-sign forecasting estimates future measurements based on recent temporal patterns and can support analysis of continuously recorded monitoring data. This study comparatively evaluated deep feedforward, recurrent, bidirectional recurrent, long short-term memory, and bidirectional long short-term memory architectures for one-step-ahead forecasting of peripheral oxygen saturation, heart rate, and pulse rate. Each model received consecutive observations of peripheral oxygen saturation, heart rate, pulse rate, respiratory rate, and age, while separate single-output models predicted the next value of the selected target.
Random and patient-wise data splitting were compared using identical input definitions, preprocessing procedures, model architectures, and training hyperparameters. The strongest architecture …
A Study On Some Distance Based Domination Parameters In Graphs And Their Applications, Shanmugavelan S Mr
A Study On Some Distance Based Domination Parameters In Graphs And Their Applications, Shanmugavelan S Mr
Theses and Dissertations
Distance-based domination has emerged as a significant development in graph theory, attributed to its applications in communication systems, interconnection networks, parallel architectures, and chemical graph models. This thesis focuses on two such graph invariants: hop domination number and 2-hop domination number of graphs. The hop domination number of some generalized graph structures like generalized thorn paths, generalized theta graphs, and snake graph families is studied along with a newly introduced family, namely generalized ciliates.
Moreover, a variant of hop domination number, namely, the 2-hop domination number, is studied for some grid families like ladder, hexagonal grid, and its variants. Furthermore, …
Effects Of Social Comparison Instructions On Affect, Motivation For Healthy Behavior, And Health Behavior Selections: Guidance To Identify Or Contrast, Raj Harsora
Theses and Dissertations
Engaging in healthy behaviors early in life is crucial for preventing noncommunicable diseases such as type 2 diabetes, cancer, and heart disease. College is an optimal period to establish these habits, yet students often engage in poor dietary and physical activity practices; thus, identifying effective health behavior change techniques for this population is essential. Social comparisons are known to influence health behaviors, yet no research has tested comparison instructions as a behavior change technique, particularly identification versus contrast with upward and downward targets. Using a preregistered protocol (https://osf.io/z29en), we tested whether guiding college students (N=664) to identify with or contrast …
Problematic Technology Use And Quality Of Life In College Students With Varying Levels Of Schizotypy, Joseph P. Skinner
Problematic Technology Use And Quality Of Life In College Students With Varying Levels Of Schizotypy, Joseph P. Skinner
Theses and Dissertations
Problematic Technology Use (PTU) has emerged as a growing concern with technology’s continual integration into daily living. Individuals higher in schizotypy may be particularly vulnerable to the negative consequences of digital environments. The present study cross-sectionally examined associations among schizotypy, PTU, and quality of life (QOL) in 533 college students using structural equation modeling. Consistent with hypotheses, greater total schizotypy was associated with higher PTU and lower QOL. Additionally, positive, negative, and disorganized schizotypy all uniquely predicted poor QOL with the negative domain demonstrating the strongest standardized association. Contrary to hypotheses, PTU did not significantly moderate the relation between total …
The Impact Of Stigma On The Mmpi-3 Scores Of An Indo-Caribbean Community Sample, Julia Persaud-Naipaul
The Impact Of Stigma On The Mmpi-3 Scores Of An Indo-Caribbean Community Sample, Julia Persaud-Naipaul
Theses and Dissertations
Evaluation of personality and psychological disorders is accomplished through the use of psychometric measures. However, tests require interpretation of test responses using a normative criterion based on a particular population that may not fully consider the effect of cultural influences on an individual’s level of willingness to report psychological difficulties. For example, individuals in collectivistic cultures may not be as willing to self-report problems because mental illness is often perceived as a source of embarrassment and shame. One culturally unique population that has been overlooked in psychological assessment is the Indo-Caribbean population. Their specific cultural values, beliefs, attitudes, and practices …
Development Of Quantum Cryptographic Algorithm For Next Generation Secure Systems, Gururaja Ts Mr
Development Of Quantum Cryptographic Algorithm For Next Generation Secure Systems, Gururaja Ts Mr
Theses and Dissertations
The rapid advancement of digital communication and quantum technologies are developing at an accelerated pace makes cybersecurity and data protection a big challenge. The traditional cryptographic methods are increasingly under attack by phishing, brute force, cryptanalytic attack and threats of quantum computing. This research presents a quantum-secure communication based on Quantum Random Number Generator (QRNG), Quantum Key Distribution (QKD), Quantum Image Encryption (QIE) and secure quantum key access using a dongle-based hardware.
QRNG models were designed in the quantum simulator and hardware. The sequences produce high entropy and they passed the statistical randomness tests with p-values higher than 0.01 indicates …
Dual-Polymer Concrete With Recycled Pet And Hdpe Aggregates: Mechanical And Durability Performance Assessment, Omar Abd El Mageed Hammouda
Dual-Polymer Concrete With Recycled Pet And Hdpe Aggregates: Mechanical And Durability Performance Assessment, Omar Abd El Mageed Hammouda
Theses and Dissertations
This study investigates the fresh, mechanical, durability, thermal, performance as well as preliminary financial aspects of dual-polymer concrete incorporating recycled polyethylene terephthalate (PET) as a partial replacement for fine aggregate and recycled high-density polyethylene (HDPE) as a partial replacement for coarse aggregate, with silica fume as a supplementary cementitious material held constant at 10% by weight of cement. The study responds to the convergence of two pressing challenges in the Egyptian context: the scale of plastic waste mismanagement, which results in widespread informal open burning and environmental contamination, and the high operational energy demand of residential buildings in Egypt's hot …
"Tithing Is An Insurance Premium": A Framing Analysis Of Speaker Innovation And Diachronic Trends In Latter-Day Saint Religious Discourse, Reid Empey
Theses and Dissertations
Religious language relies on shared metaphor and frames that contextualize religious experience and practice. Current approaches to frame semantics (Fillmore 1982) and cognitive metaphor (Lakoff & Johnson 1980) lend important insight into religious language, particularly in describing the role that figurative language serves in a religious speech community. However, a vital component of many religious speech communities is the presence of and engagement with a scriptural canon, which often contains metaphorical and framing language that religious speakers can directly reference. Yet, past conceptualizations of speech communities have not accounted for this engagement with a shared canon. To illustrate the role …
Synthetic Strategies For Bioactive Peptides: From Aggregation Inhibitors To The Total Synthesis Of Tunicyclin C, Stephanie Graciela Garcia Morin
Synthetic Strategies For Bioactive Peptides: From Aggregation Inhibitors To The Total Synthesis Of Tunicyclin C, Stephanie Graciela Garcia Morin
Theses and Dissertations
In Alzheimer's disease (AD), a brain protein called "tau" abnormally clumps and forms neurofibrillary tangles (NFTs), causing damage to brain cells. Ac-PHF6-NH2 is a hexapeptide segment of tau protein that plays a dominant role in tau aggregation and is used as a model to design tau protein aggregation inhibitors. In this research we synthesized four dehydroamino acid (□AA) containing PHF6 analogues with △Abu (derived from L-threonine) and △Val (derived from □-OH-Valine) at position 2 or 3 via dehydrations or azlactone ring-openings as key reactions. We evaluated their proteolytic resistance, ability to inhibit aggregation of PHF6, and impact on the morphology …