Digital Commons Network^™

Tc-Ptp-Mediated Regulation Of P38 Mapk Pathway Promotes Uvb-Induced Apoptosis In Skin, Lindsey Susie Shim

Theses and Dissertations

T-cell protein tyrosine phosphatase (TC-PTP) is a non-receptor PTP that has been shown to have various roles in signaling pathways. Our previous studies have demonstrated that the TC-PTP deficiency in the epidermis can exacerbate hyperplastic response by inducing epidermal cell proliferation in response to tumor promoter TPA or UVB exposure. This implies that TC-PTP plays a tumor-suppressive role in the epidermis and provides protection against UVB radiation, which is well known to contribute to skin cancer development. The p38 mitogen-activated protein kinase (MAPK) is one of serine/threonine kinases that are activated through environmental stress including UVB. It has been demonstrated …

Effect Of An Anti-Hiv Polymer Based Nanoformulation On Immune Mediating Cells Within The Gut Associated Lymphoid Tissue And Its Behavioural Impacts, Blessed Ofori

Theses and Dissertations

This thesis investigates the therapeutic potential of nanoformulated antiretroviral therapy (NF cART) and its implications for HIV-associated chronic inflammation and neurobehavioral outcomes. In the first study, NF cART demonstrated enhanced efficacy in modulating inflammasome activation and reducing viral reservoirs in gut-associated lymphoid tissue (GALT) and the small intestine of HIV-infected humanized mice. Key markers of inflammation (NLRP3, Caspase-1, and IL-1β) and viral replication (LTR and p24 levels) were significantly suppressed with NF cART compared to conventional therapy, though residual LTR expression persisted in the small intestine. In the second study, nanoformulated Emtricitabine uniquely enhanced locomotor activity and reduced anxiety-like behaviors …

Implementing Organic Fertilization Practices To Improve Aloe Vera Growth And Soil Health In The Lower Rio Grande Valley, Isaiah Edward Jaramillo

Theses and Dissertations

Aloe vera (L.) (Aloe) Burm. f., is valued for its applications across the cosmetic, medicinal, and food industries due to its leaf gel. In the aloe industry, the extraction of gel from leaves generates significant quantities of organic waste, which presents an opportunity to repurpose this material as an amendment in aloe cultivation. While Aloe is renowned for its resilience, understanding the feasibility of using these organic shavings as a soil fertility amendment in aloe production is critical. This research aims to identify sustainable fertilization methods for Aloe that can maintain and/or improve crop yield while enhancing soil health. This …

The Heroine Among Us: An Analysis Of The Feminine Principle Of The Heroine Archetype In Motion Pictures And Its Implication For Social Discourse, Neldie Gonzales

Theses and Dissertations

This thesis explores an emerging myth perceived by the rise of the feminine principle in modern society that challenges traditional gender roles. It forms a connection between the heroines seen in film and those in the real-world. It explains how the characteristics of unity, equality and love align to the feminine principle, the acquisition of which defines the archetypal hero along the hero’s journey as described by Joseph Campbell. This work proposes that stories containing this kind of archetypal hero are seeded by the discourse occurring in real-world society. Conversely, it suggests that when viewed by billions of people, blockbuster …

A Nursery Study Of The Interplay Between Soil Texture, Rooting Space, And Nurse Plants On Seedling Growth And Root Development In Woody Species Of Tamaulipan Thornscrub, Lance I. Santos

Theses and Dissertations

Reforestation attempts in semi-arid regions are plagued with seedling mortality. Blanket greenhouse practices may not be optimal, in addition, commensalism interactions between nurse plants are considered. To better understand the effects of soil texture and nurse plant interactions on growth and drought tolerance, two experiments were developed. For soil texture, Border palo verde seedlings were grown in different-sized plant bands with three soil types. To observe the effects of nurse plants, an experiment using guayacan, was developed using Texas Ebony, as a leguminous nurse plant. Plants were also exposed to a drought experiment. The results suggest that some soil textures …

Differential Effects Of Workplace Readiness Training And Job Placement Services Provided By Vocational Rehabilitation Vs School Transition Programs: A Retrospective Study Of Young Hispanic Adults, Ashley Laura Wheeler

Theses and Dissertations

This ex-post facto study, “Differential Effects of Workplace Readiness Training and Job Placement Services Provided by Vocational Rehabilitation vs. School Transition Programs: A Retrospective Study of Young Hispanic Adults” investigates differential effects of workplace readiness training and job placement services provided by vocational rehabilitation versus local education agency on employment outcomes for young, Hispanic, transition-aged youth with Autism or Intellectual Disabilities. The study examines sustained employment and differences in employment rates for individuals aged 18-23 who participated in work-based learning experiences with job coaches through VR or an LEA. Participants include 30 TAY with Autism and Intellectual Disabilities who exited …

Thank You For Your Service, Dwayne Vega

Theses and Dissertations

This thesis offers an intimate exploration of my experiences as a soldier during two deployments to Iraq, describing everyday realities of military life. Rather than glorifying the battlefield with warrior myths, I focus on the emotional toll, survival, and the complex relationships among soldiers. My narrative traces the gradual development of PTSD and my eventual reliance on drugs and alcohol as a coping mechanism. Through this personal lens, the thesis seeks to challenge common misconceptions about the soldier's life, offering a raw and authentic portrayal of service, trauma, and the lasting effects it had on my life.

Investigating The Role Of The Estrous Cycle On Memory In Syrian Hamsters, Laura Emma Garcia

Theses and Dissertations

The female reproductive system plays a significant role in cognitive function in humans and animals. For this reason, it is important to study the estrous cycle and memory in the female Syrian hamster as a model to better understand its role on cognition. Like the human female menstrual cycle, the female hamster has inconsistencies and changes in their cycles as they age. Irregular menstrual cycles and the absence of estrogen, the sex hormone necessary for supporting the sexual and reproductive health of a woman, also affect a woman’s brain, including memory (John Hopkins Medicine, 2022). In the present study, we …

Examining The Impact Of Body Esteem And Cyberbullying Victimization On Mental Health Outcomes In College-Aged Women, Lorena Victoria Houghton

Theses and Dissertations

This study investigated the role of cyberbullying victimization, body image constructs, and social anxiety on depression and suicidal ideation among 396 college-aged women. The researcher hypothesized there would be an indirect relationship between various body image-related constructs and depression/ suicidality through cyberbullying victimization and that the relationship between cyberbullying victimization and depression/ suicidal ideation would be moderated by social anxiety. Moderated mediation analyses via bootstrapping revealed cyberbullying victimization significantly mediated the relationship between various body image-related constructs (appearance-related social media consciousness, body esteem, and internalization of body ideals) and suicidal ideation while social anxiety served as a moderator between cyberbullying …

Study Of Temperature Effects Of Glucose And Microwave Dielectric Dispersion Model, Ethan Grant Boone

Theses and Dissertations

In this study, the temperature effect of dielectric properties in various aqueous solutions containing glucose are examined. A design for a new testing chamber is introduced to provide improved conditions for testing to ensure accurate and precise measurements. A N-SMA Adaptor is used when obtaining dielectric characteristics of glucose solutions ranging 100-300mg/dl. Dielectric parameters are obtained adopting a modified Debye dispersion model. MATLAB is used to confirm coaxial dimensions are suitable fabrication designs using fixed dielectric parameters of air and water. Simulations and design models were implemented utilizing ANSYS High Frequency Structure Simulator and 3-D Modeler software to develop the …

3d Bioprinted Coaxial Tubule Optimization For Human Aortic Endothelial Cell Growth, Ilse Gabriela Perez Garcia

Theses and Dissertations

This paper introduces a research study of printing parameter optimization of extruded, cell-laden, 3D bioprinted coaxial tubules, as well as cell interaction observations. Optimization of printing parameters seeks to reduce variability of the tubules’ inner and outer diameters. The tubules were manufactured from a 0.4% Collagen I - 1.6% NaC6H7O6 (Sodium Alginate) bioink, that reaches gelation through interaction with a 3.2% CaCl2 (Calcium Chloride) solution. The bioinks were extruded through a dual syringe pump mechanism connected to a coaxial nozzle, which is mounted on an adapted 3D FDM (Fused Deposition …

The Shift: Web 2.0 Tools And Learner Engagement From The Teacher Perspective, Deig Aaron Sandoval

Theses and Dissertations

The COVID-19 epidemic has altered the educational technology landscape and made Web 2.0 tools' potential for online instruction more apparent. This study uses the Decomposed Theory of Planned Behavior (DTPB) paradigm to examine teachers’ perceptions of Web 2.0 tools and online learning. The study aims to investigate and advance the expanding body of research on teachers' perceptions of Web 2.0 tools' potential to increase student participation in the classroom. The research questions examine how ready instructors are to utilize Web 2.0 tools, how they feel about using them, how perceived behavioral control variables affect their intents, and how subjective norms …

Student Loan Debt Disparity Among White, African American And Hispanic Women: A National View, Arnoldo Trejo

Theses and Dissertations

Published research into the student loan debt problem reveals a disproportionate impact on underrepresented groups within higher education, notably Hispanics, African Americans, and women students. Research on student loan debt underscores that lower-income and first-generation college students are significantly more affected when compared to their higher-income counterparts. The escalating trends in student loan debt are forcing college-going students in the United States to postpone major life events such as homeownership, marriage, and starting a family. The burden of high student debt negatively influences the accumulation of family wealth, including critical aspects such as home ownership, retirement savings, investments, and other …

Understanding Social Media As A Communicative Tool To Facilitate Critical Discourse: Using #Blackgirlmagic To Explore How Black Women In Higher Education “Talk Back", Crystal Spruill Carter

Theses and Dissertations

Black women have engaged through social media platforms, as a mechanism to uplift their embodiment, despite being relegated to the margins. The hashtag #BlackGirlMagic (BGM) is linked to narratives of Black women in higher education that are empowering and problematic. The development of the popular social media movement during a time when Black women were being portrayed negatively made engaging in the discourse "talking back" possible. This study explores the lived experiences of Black women college students and recent graduates, using currere as an analytical tool for my own communication journals entries as a data source to structure my reflections …

Examining Hispanic Beginning Farmers And Ranchers In The Rio Grande Valley Through A Community Capitals Framework, Perla Kimberly Schrock

Theses and Dissertations

While existing literature addresses the experiences of beginning farmers and ranchers (BFR), there is a notable gap in research focused on Hispanic beginning farmers and ranchers (HBFR). This study aimed at exploring the unique experiences of HBFR in a predominantly Hispanic region, the Rio Grande Valley (RGV), employed the Community Capitals Framework (Flora et al., 2016). I conducted 16 semi-structured interviews with HBFR and local nonprofit organizations and federal employees, complemented by participant observations. Through thematic and content analysis of the interview transcripts, findings revealed valuable insights into the livelihoods of HBFR. Despite HBFR facing significant challenges, this study demonstrated …

Leveraging A Community Of Practice To Advance Stem Education Reform And Promote Teacher And Student Self-Efficacy, Ruth Renee Colyer

Theses and Dissertations

This dissertation examined the impact of the CREST-MECIS community of practice on K-12 STEM teachers and undergraduate and graduate students, addressing the urgent need for innovative approaches in science education to meet the challenges of the 21st century. The study was grounded in response to three primary problem statements: 1) the significant learning losses and socio-emotional challenges stemming from the COVID-19 pandemic, 2) the inadequacy of traditional instructional methods in post-pandemic classrooms, and 3) the need for culturally relevant and inclusive teaching practices that acknowledge students’ lived experiences. Data were collected through pre- and post-interviews, survey analyses, and qualitative feedback …

Community Reintegration Of Previously Incarcerated Individuals From A Virtue Perspective, Cindy Noemi Hernandez

Theses and Dissertations

Community reintegration is one of the most important indicators that determine the success of previously incarcerated individuals’ rehabilitation. It is influenced by several factors such as support, attitudes, strengths, and virtues. One emerging area of study that can be related to community reintegration is virtue. The concept of virtue has received increasing attention in rehabilitation research, focused on how one’s virtuous pursuit of excellence improves well-being and adaptation (Kim et al., 2016). In that community reintegration is a type of life adjustment, virtue can be related to community reintegration. The present study examined community reintegration and perceived support of previously …

Challenges And Strategies In Science Learning: A Thematic Review And Meta-Analysis, Angelica A. Guanzon

Theses and Dissertations

This study thoroughly explores the relationships between the challenges faced by students and the alternative problem-solving strategies employed. By analyzing these connections, the research aims to offer a comprehensive understanding of how students address difficulties in science learning and the adaptive strategies they apply. Through this research, teachers can gain valuable understanding in adapting learning resources that successfully address diverse needs of students. By identifying specific challenges and correlating effective strategies, targeted interventions are designed to enhance the overall science learning experience. The study emphasizes the importance of a dynamic and adaptable teaching approach that caters to the evolving landscape …

The Role Of Hope In Recovery From Sexual Assault For Hispanic Women, Esmeralda Rivera

Theses and Dissertations

Despite a growing amount of academic literature, there is a lack of research examining the levels of hope in Hispanic women recovering from sexual assault trauma. This quantitative survey investigates hope in Hispanic women healing from sexual assault trauma. The Miller Hope Scale (MHS) examines the variations and correlations between degrees of hope and demographic, personal, and self-advocacy factors. The research employs the Trauma Symptom Checklist—40 to investigate the correlation between levels of hope and trauma among women who have undergone sexual assault. Ninety-one Hispanic women from a crisis center in the U.S. were recruited for the study. Descriptive statistics, …

Assessing Cover Crop Adoption Factors In The Rio Grande Valley Through A Social-Ecological Perspective, Mackenzie Feldman

Theses and Dissertations

Reducing agriculture’s negative environmental impacts is crucial for mitigating climate change (White, 2021). Cover crops– non-cash crops grown to benefit subsequent cash crops– can slow erosion, improve soil health, enhance water availability, control pests, and increase biodiversity. Despite these benefits, adoption rates remain low, prompting the USDA and other organizations to fund research on increasing their use. Most studies focus on the Midwest and Northeast, and emphasize individual factors over the relationship between structural factors and individual factors that impact farmers’ decisions to adopt cover crops. This USDA-funded study begins to fill this gap by exploring social-ecological factors and how …

Emotion Regulation From A Virtue Perspective: Applications For Individuals With Adverse Childhood Experiences, Maria Eugenia Palomo

Theses and Dissertations

The purpose of this study is to explore the contributory effect of Virtues in differentiating one’s ability to regulate emotion. Convenience sampling will be utilized to obtain a total of 102 participants who had adverse childhood experiences. Participants will be recruited via collaboration with local behavioral counseling agencies. Two behavioral health counseling agencies located in Hidalgo County, including Corazon Consulting, Inc. and A Better Tomorrow, LLC, have agreed to be part of the present study. The research packets used in this study consisted of two parts: 1) a demographic information form, and 2) a research questionnaire that includes three instruments …

Sustainability Of Military Values Post Military Service: A Quantitative Study, Jennifer Ann Jazinski

Theses and Dissertations

Military-to-civilian transitioning represents a multidimensional process of adjustment, encompassing mental and physical health, basic physiological needs, practical (e.g., employment), and cultural domains. The intent of this study is to examine the sustainability of military values (e.g., duty, integrity, ethics, honor, courage, and loyalty) post-military service and to identify whether reported levels of sustained military values impact veterans’ reported level of Quality of Life (QoL). This study will assess the impacts demographic variables (e.g., gender, ethnicity, relationship status, age, number of children, highest level of education, student status, employment status, comfort with finances, living status, county of residence). and military service …

The Association Between Childhood Trauma And Adulthood Depression And Posttraumatic Symptoms. Mediated Through Emotion Regulation And Perceived Social Support., Josue David Luna Jr.

Theses and Dissertations

Depression and posttraumatic stress are two psychological consequences commonly reported by adults exposed to adverse childhood experiences. High prevalence of childhood adversities in the United States is a significant concern. Despite this, the specific causal mechanisms connecting childhood adversity to adult psychopathology remain undiscovered and require further research. This research aimed to determine whether perceived social support, cognitive reappraisal, and expressive suppression, two alternate forms of emotion regulation, would independently mediate the link between adverse childhood experiences and psychopathology in adulthood among a sample of U.S. Hispanic students. A total of 814 undergraduate students completed an anonymous online battery of …

Using Nano-Ities For Detection Of Metal Ions In Complex Aqueous Solutions, Mohammed Muzammil Nishar Ahmed

Theses and Dissertations

Recent urbanization has induced a rapid increase in heavy metal exposure to humans. The exploitation of heavy metals for economic gains coupled with poor and economically infeasible recycling methods have led to poor management of heavy metal wastes, which has opened up several pathways for heavy metals to enter the human body. Such heavy metals target many vital organs, but the early symptoms are common and difficult to diagnose. Severe symptoms appear in later stages and are very expensive to treat and the damage caused to the health are not typically reversable in such later stages. To counter this issue, …

Impact Of State-Level Family Policies On Female Labor Force Participation And Entrepreneurship, Kathryn Staczek Rudloff

Theses and Dissertations

This dissertation aims to investigate the impact of state-level family policies on women's participation in the labor force in the United States, focusing specifically on the rise of self-employment and solopreneurship among women. The research seeks to answer the following question: "How do family policies at the state level impact participation of American women in the labor force?"

The study utilized a convergent parallel mixed-methods design. A composite index of state level family policies was created to conduct cross-sectional exploratory data analysis of female labor force participation. Additionally, a qualitative phenomenological study of solopreneurs provided a deeper understanding of the …

Ecological And Pathological Applications Of The Heat Shock Response, Taylor Rae Stanley

Theses and Dissertations

The heat shock response (HSR) is a cytoprotective stress response pathway that regulates cellular proteostasis. The HSR is an evolutionarily conserved pathway that is essential for normal cellular functioning. Here, we explore the broad ecological and pathological impacts of the HSR. In an ecological context, we perform gene level analysis of the transcriptomes of two closely related sunfish. We found that the more invasive bluegill sunfish has gene expansions in two HSR gene families, the HSP70 family and the HSP90 family compared to the redear sunfish. These gene expansions were also observed in several other teleost fish species and were …

Adsorption Of Harmful Algal Bloom Toxins Using Biochar, Cadianne Chambers

Theses and Dissertations

Harmful Algal Bloom (HAB) events involve the proliferation of microalgae which discharge lethal toxins into fresh and brackish water bodies due to anthropogenic and climatic activities. Common examples of HABs include causative organisms such as Cyanobacteria, Pyrodinium bahamense and more. These genera are known to release potent toxins including Microcystins, and Saxitoxins, respectively, which can seriously endanger human and marine health. Ingestion of these toxins can result in several health problems, such as nausea, vomiting, gastroenteritis, skin irritation, liver damage, paralysis, and respiratory arrest. The Great Lakes, Gulf of Maine, Florida’s coasts, Lake Erie, and Lake Okeechobee have all been …

Tac-It An Affective Computing User Interface Design, Andrew Biron

Theses and Dissertations

TAC-IT affective computing user-interface design is an independent computer peripheral that is a tool to be utilized to obtain a user’s self-reported emotional state in real-time. Doctor Rosalind Picard first coined and used the term affective computing in her paper Affective Computing [Picard, R. (1995)]. Affective Computing is defined as the study and development of systems and devices that can recognize, interpret, process, and simulate human affects. It is an interdisciplinary field spanning computer science, psychology, and cognitive science. Since that time, areas of research have expanded exponentially, and areas of interest include how to trigger emotions in a test …

Investigation Of Reproductive Inhibition During Chronic Heat Stress In C. Elegans, Macy Makenna Nielander

Theses and Dissertations

Nearly all organisms experience heterogeneity in environmental conditions that can negatively impact fitness. A common adaptive strategy to reduce the impact of this stress is called facultative diapause, where development and reproduction are temporarily arrested to promote survival. Facultative diapause is characterized by three major criteria, the arrest must be (i) induced by an unfavorable environmental condition, (ii) reversible, and (iii) driven by genetically regulated mechanisms. The aim of this thesis was to determine whether chronic heat-induced inhibition of egg laying in Caenorhabditis elegans represents a novel form of facultative diapause. It was found that the inhibition of egg-laying is …

Theoretical Advancements In Hawkes Processes And Their Practical Applications, Xi Zhang

Theses and Dissertations

Hawkes self-exciting point processes have been widely used in fields such as seismology, finance and social media analysis. Despite decades of research focusing on these processes, several key aspects remain under-explored. These include broadly applicable methods for model evaluation and selection, intuitive nonparametric inference approaches akin to kernel density estimation for probability density functions, and strategies to enhance the performance of generative point process models in predictive tasks. In this dissertation, first, we extend the time-rescaling theorem, which is traditionally limited to non-terminating processes with complete observations, to accommodate terminating processes and incomplete observations as well. This extension allows for …