Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Life Sciences (2633)
- Arts and Humanities (2256)
- Social and Behavioral Sciences (1516)
- Medicine and Health Sciences (1253)
- Engineering (1173)
-
- Physical Sciences and Mathematics (1136)
- Education (831)
- Psychology (598)
- Biology (506)
- Animal Sciences (497)
- Art and Design (418)
- Fine Arts (328)
- Computer Sciences (297)
- English Language and Literature (294)
- History (286)
- Biochemistry, Biophysics, and Structural Biology (284)
- Chemistry (277)
- Religion (264)
- Medical Sciences (251)
- Biomedical Engineering and Bioengineering (237)
- Mormon Studies (218)
- Environmental Sciences (208)
- Plant Sciences (198)
- Physiology (197)
- Art Practice (195)
- Communication (191)
- Pharmacy and Pharmaceutical Sciences (187)
- Electrical and Computer Engineering (186)
- History of Art, Architecture, and Archaeology (176)
- Sociology (175)
- Institution
-
- University of North Dakota (2742)
- Brigham Young University (2458)
- Virginia Commonwealth University (2343)
- Mississippi State University (1936)
- University of South Carolina (1162)
-
- City University of New York (CUNY) (654)
- Air Force Institute of Technology (597)
- Rowan University (489)
- American University in Cairo (472)
- University of Texas Rio Grande Valley (459)
- Illinois State University (419)
- University of Arkansas Little Rock (268)
- Florida Institute of Technology (259)
- Pepperdine University (201)
- St. John's University (167)
- Columbus State University (128)
- SASTRA Deemed to be University (76)
- Nova Southeastern University (69)
- Texas A&M International University (69)
- University for Business and Technology in Kosovo (60)
- UAlaska System (3)
- Seattle Pacific University (2)
- Keyword
-
- Utah (170)
- History (120)
- Painting (118)
- Art (102)
- Education (89)
-
- North Dakota (89)
- Sculpture (87)
- Gender (82)
- Inflammation (78)
- Memory (76)
- United States (72)
- Cancer (69)
- Machine learning (63)
- Women (58)
- Biochemistry (56)
- Installation (56)
- Mormons (55)
- Technology (55)
- Performance (52)
- Poetry (52)
- Identity (51)
- Autism (50)
- Agriculture (49)
- Behavior (49)
- Ecology (49)
- Feminism (49)
- Mitochondria (49)
- Mormon Church (48)
- Biological sciences (47)
- Depression (47)
- Publication Year
- File Type
Articles 9481 - 9510 of 15033
Full-Text Articles in Entire DC Network
Life, The Multiverse, And Everything: How Crisis On Infinite Earths Changed Dc Comics, Kate Simonsen
Life, The Multiverse, And Everything: How Crisis On Infinite Earths Changed Dc Comics, Kate Simonsen
Theses and Dissertations
Published from 1985 to 1986, DC Comics’ Crisis on Infinite Earths created the expectation that each crossover will result in numerous deaths and alter the structure or history of the DC Universe. Since many of these changes, such as the death of a popular or iconic character, cannot be sustained long term, the success and influence of Crisis on Infinite Earths led to the erosion of the very elements that made it shocking. Entire worlds can be destroyed, but superreaders eventually suspect that no change is ever permanent and, as more iconic characters are revived or rebooted, death is no …
Mandibular Symphyseal Distraction Osteogenesis (Msdo): Association With Temporomandibular Dysfunction (Tmd) Symptoms, Sheldon Bates
Mandibular Symphyseal Distraction Osteogenesis (Msdo): Association With Temporomandibular Dysfunction (Tmd) Symptoms, Sheldon Bates
Theses and Dissertations
Background: Transverse mandibular discrepancies are often overlooked during orthodontic treatment. MSDO is a treatment to address this issue, but much debate exists over the long-term implications on the temporomandibular joint (TMJ). Few studies have sample sizes sufficient to draw clear conclusions about the impact of MSDO on TMJ health. Materials and Methods: This study evaluated private practice records including 49 MSDO patients and 57 traditionally-treated controls. The subjects were assessed by TMD exams that evaluated jaw pain and discomfort using visual analog scales, range of motion for opening, right and left lateral, and protrusive movements, and the presence of clenching, …
Dismemory: On History, The Southern Imaginary, And Abusing The Visual Record, Matthew Pendleton Shelton
Dismemory: On History, The Southern Imaginary, And Abusing The Visual Record, Matthew Pendleton Shelton
Theses and Dissertations
Using the literary device of a fictional interview between the artist and a sympathetic intellectual, I explore concepts relating to subjectivity, pedagogy, memory, “Southernness,” whiteness, the deceptive nature of images, social justice, and 20th century art as they relate to a contemporary artistic practice.
Assessing The Genotoxicity Of Triclosan In Tadpoles Of The American Bullfrog, Lithobates Catesbeianus., David Emery
Assessing The Genotoxicity Of Triclosan In Tadpoles Of The American Bullfrog, Lithobates Catesbeianus., David Emery
Theses and Dissertations
Amphibians are particularly sensitive to environmental degradation and, therefore, serve as effective environmental quality indicators. Research has suggested that amphibian declines are exacerbated by manmade environmental toxicants, especially those found in high concentrations in urban areas. The NIH has pinpointed genotoxicity as a major route of cancer causation, and has since developed stringent testing procedures for potentially hazardous chemicals. One such method, recognized for its simplicity and economy, is the micronucleus assay. A study was conducted assessing the genotoxicity of the widely used antimicrobial agent Triclosan to American Bullfrog tadpoles. Lithobates catesbeianus tadpoles were reared in glass aquaria containing ultra-high …
Thin Time, Jonathan Benjamin
Thin Time, Jonathan Benjamin
Theses and Dissertations
THIN TIME by Jonathan Benjamin, MFA in Sculpture + Extended Media A thesis submitted in partial fulfillment of the requirements for the degree of Master of Fine Arts in Sculpture + Extended Media at Virginia Commonwealth University. Virginia Commonwealth University, 2012. Major Director: Corin Hewitt, Assistant Professor, Department of Sculpture + Extended Media This thesis is an honest attempt to put language to a non-lingual practice. It describes my studio process, my thoughts on materials and surface, and outlines some of the images and things out in the world that inform my work.
Examining Racial Differences In Sympathetic Activity Assessed During Recovery From Exercise In Obese Adolescent Females, Stacey Hall
Theses and Dissertations
Sympathetic overactivity (SO) is associated with obesity and cardiovascular disease (CVD) mortality. Black adolescents have an increased risk of obesity and CVD later in life, particularly females. PURPOSE: To evaluate differences in SO between black (BOA) and white obese female adolescents (WOA). METHODS: Sixty-one BOA (n=49, 13.7±1.6 yrs, 38.1±6.1 kg/m2) and WOA (n=12, 13.3±2.2 yrs, 34.3±4.9 kg/m2) completed a maximal graded treadmill test after which an exercise recovery index (ERI; heart rate/VO2 plateau) was calculated. RESULTS: The ERI was significantly greater in BOA compared to WOA (29.8 ± 6.4 vs. 24.1 ± 3.1, P = 0.004). Multiple linear regression modeling …
Tgf-Beta Receptors And Alcohol Sensitivity In Drosophila, Kristyn Sennett
Tgf-Beta Receptors And Alcohol Sensitivity In Drosophila, Kristyn Sennett
Theses and Dissertations
Clic proteins influence ethanol-related behavior in flies and other species and also mediate TGF-β signaling. These findings suggest that Clics and the TGF-β signaling pathway might work together to modulate behavioral responses to ethanol. I used the Drosophila model to address the hypothesis that TGF-β signaling is important for ethanol sensitivity. Ethanol sensitivity was blunted by multiple transposon insertions in the TGF-β receptor gene thickveins. Collectively, however, I found no consistent correlation between expression of thickveins and altered ethanol sensitivity in flies harboring transposons. I therefore also assessed ethanol sensitivity in flies with loss of function point mutations in thickveins. …
The Role Of Sulfatide In The Development And Maintenance Of The Nodal And Paranodal Domains In The Peripheral Nervous System, Heather Herman
The Role Of Sulfatide In The Development And Maintenance Of The Nodal And Paranodal Domains In The Peripheral Nervous System, Heather Herman
Theses and Dissertations
Sulfatide is a galactolipid and a major lipid component of the myelin sheath. Its production is catalyzed by the enzyme cerebroside sulfotransferase (CST). To determine the functions of sulfatide, the gene encoding CST was genetically disrupted resulting in mice incapable of sulfatide synthesis. Using these mice, it has been shown in the central nervous system (CNS) that sulfatide is essential for normal myelin synthesis and stability even though the onset of myelination is not impaired. Additionally, proper initial clustering of paranodal proteins and cluster maintenance of nodal proteins is impaired suggesting that paranodal domains are important for long-term node stability. …
Blues Trope As A Cultural Intersection In Alice Walker's The Temple Of My Familiar And Sherman Alexie's Reservation Blues, Julia Leuthardt
Blues Trope As A Cultural Intersection In Alice Walker's The Temple Of My Familiar And Sherman Alexie's Reservation Blues, Julia Leuthardt
Theses and Dissertations
Though bound historically through hundreds of years, the African-Native American relation has not received much attention by scholars of literature; hence, the emphasis of this thesis is to investigate the literary portrayal of the interethnic relation between African Americans and Native Americans through the blues trope. The blues trope provides an intriguing literary platform for the psychological and physical struggles in finding an identity within such a diverse multiethnic society like the United States. For African American writer Alice Walker and Native American author Sherman Alexie the blues trope is a successful literary device in expressing long lost and rediscovered …
Fullerene C70 Derivatives Dampen Anaphylaxis And Allergic Asthma Pathogenesis In Mice, Sarah Norton
Fullerene C70 Derivatives Dampen Anaphylaxis And Allergic Asthma Pathogenesis In Mice, Sarah Norton
Theses and Dissertations
Fullerenes are carbon nanospheres that can be solublized by the addition of polar chemical groups to the carbon cage, forming fullerene derivatives. One specifically derivatized fullerene compound, termed C70-Tetragylocolate (C70-TGA), has been shown to stabilize mast cell responses in vitro thus we hypothesized it may have an effect on mast cell-driven diseases such as asthma and systemic anaphylaxis. To observe the effects of C70-TGA on systemic anaphylaxis, mice were subjected to a model of passive systemic anaphylaxis. In this model, mice were injected with DNP-specific IgE 16 hours prior to challenge, then treated with C70-TGA. Immediately prior to DNP challenge, …
Method In Motion: Grounding A Movement Pedagogy In The Lessons Of Stanislavski, Kevin Inouye
Method In Motion: Grounding A Movement Pedagogy In The Lessons Of Stanislavski, Kevin Inouye
Theses and Dissertations
This thesis is an exploration of movement pedagogy as a continuation of basic acting lessons from Stanislavski. Using the example of an introductory semester of movement instruction, physical acting and movement concepts are explained in terms of their connection to and derivation from universally accepted acting terminology and ideas. This is put forth as a way to facilitate the synthesis of movement instruction with other acting curriculum, as well as providing a new way to view some familiar acting concepts. Several specific examples are explored in more depth as case studies in physical equivalents to the intellectual, visual, or emotional …
The Portrayal Of Older People In Marketing Materials For Senior Centers, Jason Robert Gillespie
The Portrayal Of Older People In Marketing Materials For Senior Centers, Jason Robert Gillespie
Theses and Dissertations
This content analysis examined 128 senior center brochures and newsletters to determine how older people (those 65 years and older) were portrayed. Findings indicated that portrayals of older people in this medium that targets older people and their caretakers exclusively were overwhelmingly positive. Older people were portrayed favorably in terms of health status, personality descriptors related to level of happiness, interaction with others, mental state, as well as body image and overall evaluation. In several other categories such as energy level and activity level they were portrayed neutrally, and not a single category was dominated by negative portrayals. In fact, …
Three Dimensional In Vitro Model Of Head And Neck Squamous Cell Carcinoma, Anna Bulysheva
Three Dimensional In Vitro Model Of Head And Neck Squamous Cell Carcinoma, Anna Bulysheva
Theses and Dissertations
Head and neck squamous cell carcinomas (HNSCC) are among the leading causes of cancer related deaths throughout the world. The survival rate for this type of cancer is extremely low and has not changed significantly in recent decades. There is an imperative need to study tumor progression in a representative model in order to generate more knowledge about this disease as well as develop more effective treatment options. Multiple methods already exist for studying HNSCC and other types of cancers, including in vitro and in vivo models. Although in vivo models are more representative of the human carcinomas in terms …
Iron Deficiency Causes A Shift In Amp-Activated Protein Kinase (Ampk) Catalytic Subunit Composition In Rat Skeletal Muscle, John Merrill
Iron Deficiency Causes A Shift In Amp-Activated Protein Kinase (Ampk) Catalytic Subunit Composition In Rat Skeletal Muscle, John Merrill
Theses and Dissertations
To determine effects of iron deficiency on AMPK activation and signaling, as well as the AMPKα subunit composition in skeletal muscle, rats were fed a control (C=50-58 mg/kg Fe) or iron deficient (ID=2-6 mg/kg Fe) diet for 6-8 wks. Their respective hematocrits were 47.5% ± 1.0 and 16.5% ± 0.6. Iron deficiency resulted in 28.3% greater muscle fatigue (p<0.01) in response to 10 min of stimulation (1 twitch/sec) and was associated with a greater reduction in phosphocreatine (C: Resting 24.1 ± 0.9 micromol/g, Stim 13.1 ± 1.5 micromol/g; ID: Resting 22.7 ± 1.0 micromol/g, Stim 3.2 ± 0.7 micromol/g; p<0.01) and ATP levels (C: Resting 5.89 ± 0.48 micromol/g, Stim 6.03 ± 0.35 micromol/g; ID: Resting 5.51 ± 0.20 micromol/g, Stim 4.19 ± 0.47 micromol/g; p<0.05). AMPK activation increased with stimulation in muscles of C and ID animals. A reduction in Cytochrome c and other iron-dependent mitochondrial proteins was observed in ID animals (p<0.01). The AMPK catalytic subunit (alpha) was also examined because both isoforms are known to play different roles in responding to energy challenges. In ID animals, AMPK alpha2 subunit protein content was reduced to 71.6% of C (p<0.05), however this did not result in a significant difference in resting AMPK alpha2 activity. AMPK alpha1 protein was unchanged, however an overall increase in AMPK alpha1 activity was observed (C: 0.91 pmol/mg/min; ID: 1.63 pmol/mg/min; p<0.05). Resting phospho Acetyl CoA Carboxylase (pACC) was unchanged. This study indicates that chronic iron deficiency causes a shift in the expression of AMPK alpha subunit composition and potentially altered sensitivity to cellular energy challenges.
Hydrogen Sulfide As An Allosteric Modulator Of Atp Sensitive Potassium Channels In Colonic Inflammation., Aravind Gade
Hydrogen Sulfide As An Allosteric Modulator Of Atp Sensitive Potassium Channels In Colonic Inflammation., Aravind Gade
Theses and Dissertations
The ATP sensitive potassium channel (KATP) in mouse colonic smooth muscle cell is a complex containing a pore forming subunit (Kir6.1) and a sulfonyl urea receptor subunit (SUR2B). These channels are responsible for maintaining the cellular excitability of the smooth muscle cell which in turn regulates the motility patterns in the colon. We used whole-cell voltage-clamp techniques to study the alterations in these channels in smooth muscle cells in experimental model of colitis (colonic inflammation). Colitis was induced in BALB/C mice following an intracolonic administration of trinitrobenzene sulfonic acid (TNBS). KATP currents were measured at Vh -60 mV in high …
Joseph As Father In Guido Reni's St. Joseph Images, Alec Teresa Gardner
Joseph As Father In Guido Reni's St. Joseph Images, Alec Teresa Gardner
Theses and Dissertations
This study presents a psychoanalytic examination of Guido Reni's motivations for creating an innovative painting series of St. Joseph and the Christ Child. The seventeenth-century artist developed a new depiction of Joseph as the tender and loving surrogate father of Christ. This new artistic emphasis on the intimate relationship between father and son reveals Reni's own psychological need to create a replacement father. Indeed, contemporary biographers report that Reni suffered from anxiety and an aversion to women throughout his life. These odd behavioral traits appear to have stemmed from Reni's lack of a supportive father figure. Thus, the artist created …
A Content Analysis Of Inquiry In Third Grade Science Textbooks, Rebecca Adams Lewis
A Content Analysis Of Inquiry In Third Grade Science Textbooks, Rebecca Adams Lewis
Theses and Dissertations
Since the publication of the National Science Education Standards in 1996 efforts have been made to include inquiry into school science programs. An addendum on inquiry to these standards was published in 2000 presenting five essential features of classroom inquiry as indicators of the active use of inquiry in a science lesson. The purpose of this content analysis was to examine and identify the presence of these five essential features of classroom inquiry within publisher-identified inquiry activities found in the 2000 and 2010 teacher's editions of the third grade science textbooks published by Scott Foresman. The textbooks were read and …
Extending The Quikscat Data Record With The Oceansat-2 Scatterometer, Joshua P. Bradley
Extending The Quikscat Data Record With The Oceansat-2 Scatterometer, Joshua P. Bradley
Theses and Dissertations
Originally designed for wind velocity estimation over the ocean, scatterometers have since been applied to climate studies of the Earth's cryosphere and bioshere. As an integral part of climatological studies of the planet, the NASA Scatterometer Climate Record Pathfinder (SCP) supplies scatterometer-based products designed to aid researchers in climatological studies of the planet. In this thesis, necessary steps are taken to facilitate data from the Oceansat-2 Ku-band scatterometer (OSCAT) to be used in extending the Ku-band SCP dataset of conically scanning pencil-beam scatterometers begun by the Seawinds scatterometer flown on the QuikSCAT mission 1999-2009. As a standard SCP product, a …
Poppies And Ptsd: Opioid Influence On A Preclincal Model Of Posttraumatic Stress Disorder., Sarah Vunck
Poppies And Ptsd: Opioid Influence On A Preclincal Model Of Posttraumatic Stress Disorder., Sarah Vunck
Theses and Dissertations
Posttraumatic Stress Disorder (PTSD) is an anxiety disorder that affects over 7.7 million adults and carries an estimated societal cost of $3.1 billion every year. People develop PTSD after exposure to a traumatic event. Alone or combined, approved pharmacotherapies or psychotherapy are somewhat effective, but symptoms for many remain refractory. Emerging evidence suggests that opiate systems may modulate the development and expression of PTSD, and their role can be investigated preclinically. Pavlovian fear conditioning is a preclinical model which elicits behaviors mirroring those that occur in humans during and after exposure to trauma. This presents an experimental tool that can …
Overexpression Of Serum Response Factor In Astrocytes Improves Neuronal Plasticity In A Model Of Fetal Alcohol Spectrum Disorders, Arco P. Paul
Theses and Dissertations
Neuronal plasticity deficits underlie many of the neurobehavioral problems seen in Fetal Alcohol Spectrum Disorders (FASD). Recently, we showed that third trimester alcohol exposure lead to a persistent disruption in ocular dominance (OD) plasticity. For instance, few days of monocular deprivation results in a robust reduction of cortical regions responsive to the deprived eye in normal animals, but not in ferrets exposed early to alcohol. This plasticity deficit can be reversed if alcohol-exposed animals are treated with a phosphodiesterase type 1 (PDE1) inhibitor during the period of monocular deprivation. PDE1 inhibition can increase cAMP and cGMP levels, activating transcription factors …
The Relationship Between Physical Fitness And Executive Control Functioning In Young Adults, Margaret L. Cowles
The Relationship Between Physical Fitness And Executive Control Functioning In Young Adults, Margaret L. Cowles
Theses and Dissertations
Physical fitness is associated with overall health and well-being. Increasing evidence, primarily among older adults, supports the link between physical health and cognitive health, particularly with subset of cognitive processes known as executive control functioning. Executive control functioning is needed to complete complex, goal-directed activities and involves the capacity to initiate and discontinue behaviors appropriately, to monitor and modify actions as needed, to plan future behavior when faced with novel tasks and situations, and to anticipate future outcomes. To date, researchers studying the link between physical fitness and executive control functioning have largely focused on older adults and have defined …
Comparative Analysis Of Yersinia Pestis Infection In Resistant And Susceptible Mice, Nathaniel D. Lambert
Comparative Analysis Of Yersinia Pestis Infection In Resistant And Susceptible Mice, Nathaniel D. Lambert
Theses and Dissertations
This study demonstrates that 2 month old, female B10.T(6R) are highly resistant to systemic infection with the KIM5 strain of Yersinia pestis , and that B10.T(6R) mice become susceptible to Y. pestis infection by 5 months of age. In this study we infected both young (2 month) and middle-aged (5-12 month) B10.T(6R) with equal CFUs of Y. pestis. LD50 of young B10.T(6R) was ∼1.4 X 10 4 CFU, while middle-aged B10. T(6R) mice exhibited an LD50 of ∼60 CFU. An elevated bacterial burden was found in the spleens of middle-aged mice at 24 and 60 h and the livers at …
Executive Functioning And Childhood Abuse Predictors On Laboratory Induced Aggression, Jessica R. Mugge
Executive Functioning And Childhood Abuse Predictors On Laboratory Induced Aggression, Jessica R. Mugge
Theses and Dissertations
Previous research has indicated that neuropsychological dysfunction and the experience of violence during childhood are linked to the acquisition and expression of aggressive behavior. How these variables interact to influence aggression has not been effectively established in the literature, however. This study provided a prospective examination of the relationships between EF, the experience of childhood abuse, and aggression. Based on responses on a pre-screening questionnaire that assessed EF (BRIEF-A), 101 participants at a Midwestern university were selected for inclusion in this study. Fifty participants were classified as at risk for EF deficits (24 males, 26 females) while 51 participants were …
Production Of A Transgenic Mouse That Specifically Overexpresses The Antioxidant Metallothionein In Endothelial Cells, Jennifer M. Teiken
Production Of A Transgenic Mouse That Specifically Overexpresses The Antioxidant Metallothionein In Endothelial Cells, Jennifer M. Teiken
Theses and Dissertations
Diabetes mellitus increases the risk for cardiovascular disease due, in part, to hyperglycemia-induced oxidative stress. To investigate the potential for antioxidant protection of the vasculature, a transgenic mouse (Jtmt) that overexpresses the antioxidant metallothionein (MT) specifically in endothelial cells (EC) was produced. A 16kb transgene consisting of the murine Tie2 promoter and enhancer ligated to the human MTII gene was microinjected into FVB mouse embryos. Two founder mice, Jtmt1 and Jtmt4, produced transgenic progeny identified by PCR using human MTII primers. At 60 days of age, there were no distinguishable differences in phenotype, behavior, body and organ weights, and glucose …
Characterization Of Truncated Yscf: Innate Immune And Proinflammatory Responsiveness, Melody N. Toosky
Characterization Of Truncated Yscf: Innate Immune And Proinflammatory Responsiveness, Melody N. Toosky
Theses and Dissertations
Yersinia pestis, the causative agent of plague, is a highly pathogenic gram negative bacterium that attenuates the host immune response by translocating effector proteins, known as Yops, directly from the bacterial cytoplasm into the eukaryotic cell cytoplasm using a Type III secretion system. The Type III secretion system uses a polymerized needle to translocate Yops into the eukaryotic cell. This self-polymerizing needle is composed of YscF. YscF has been tested as a possible vaccine alternative to other subunit vaccines. Wild type YscF has been previously shown to provide a low amount of protection against challenge with Y. pestis. The focus …
Lipid Emulsion Therapy For Local Anesthetic Systemic Toxicity, Jenna Klabunde
Lipid Emulsion Therapy For Local Anesthetic Systemic Toxicity, Jenna Klabunde
Theses and Dissertations
This paper explores Local Anesthetic Systemic Toxicity (LAST) and the effectiveness of lipid emulsion (LE) therapy as a potential treatment modality. Regional anesthesia is a common method of anesthesia due to the significant benefits in both the perioperative and postoperative periods. LAST is a potential complication of regional anesthesia due to local anesthetic inadvertently entering the bloodstream and causing central nervous system and cardiac toxicities. Extensive research was performed through highly respected, evidence-based search engines to gather evidence of LE therapy for LAST. Through numerous animal studies, literature reviews, systematic reviews, and case reports that were reviewed to complete this …
Demand For Sanitation And Hygiene In Rural Households In Cameroon: Case Of And Njinikom Village, Irin A. Njuakom
Demand For Sanitation And Hygiene In Rural Households In Cameroon: Case Of And Njinikom Village, Irin A. Njuakom
Theses and Dissertations
Inadequate sanitation and hygiene remain a major health concern in the world today with ill effects that are particularly debilitating in developing nations. Preventable diseases related to poor sanitation (inadequate human waste disposal) and lack of hygiene are estimated to kill some 3900 children daily and are the leading causes of increasing morbidity and mo1iality among the poor in the world. The issue of inadequate sanitation and hygiene has been construed as a problem of the poor. ln the impoverished village of Njinikom in Cameroon, the lack of access to basic sanitation and hygiene is apparent in the practice of …
Myelin Gene Expression: Implications For Alcohol Abuse And Dependence, Sean Farris
Myelin Gene Expression: Implications For Alcohol Abuse And Dependence, Sean Farris
Theses and Dissertations
Acute behavioral responses to ethanol have predictive value for determining an individual's risk of long-term drinking behavior. Although the neurobiology of alcohol abuse is complex, prior studies from our laboratory demonstrated differential myelin-associated gene expression (MAGE) in medial prefrontal cortex (PFC) as one potential mechanism influencing acute ethanol behaviors between C57BL/6J (B6) and DBA/2J (D2) mice. Our laboratory and others have also shown MAGE is reduced in PFC of alcoholics. Herein, I have extended these findings through expression profiling of PFC into chronic models of ethanol self-administration from non-human primates and mice. Together, these results suggest that regulation of MAGE …
Antinociceptive Effects Of Monoamine Reuptake Inhibitors In Assays Of Pain-Stimulated And Pain-Depressed Behaviors, Marisa Rosenberg
Antinociceptive Effects Of Monoamine Reuptake Inhibitors In Assays Of Pain-Stimulated And Pain-Depressed Behaviors, Marisa Rosenberg
Theses and Dissertations
ANTINOCICEPTIVE EFFECTS OF MONOAMINE REUPTAKE INHIBITORS IN ASSAYS OF PAIN-STIMULATED AND PAIN-DEPRESSED BEHAVIOR By Marisa B. Rosenberg A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science at Virginia Commonwealth University. Virginia Commonwealth University, 2012 Advisor: Sidney Stevens Negus, Ph.D. Professor, Department of Pharmacology/Toxicology Noxious stimuli can produce pain-related stimulation of some behaviors (e.g. withdrawal responses) and depression of other behaviors (e.g. feeding, locomotion, responding maintained by many types of positive reinforcement). Monoamine reuptake inhibitors are used clinically to treat depression and to manage some types of pain. This study examined the antinociceptive properties …
Assessing Deployment Risk And Resiliency Factors And The Adjustment Outcomes Of Police Officers Serving In Operation Iraqi Freedom And Operation Enduring Freedom, Paula Barrows
Theses and Dissertations
ASSESSING DEPLOYMENT RISK AND RESILIENCY FACTORS AND THE ADJUSTMENT OUTCOMES OF POLICE OFFICERS SERVING IN OPERATION IRAQI FREEDOM AND OPERATION ENDURING FREEDOM By Paula Barrows Davenport, MS A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia Commonwealth University. Virginia Commonwealth University, 2012 Director: Dr. Janet R. Hutchinson Professor and Chair of the Department of Gender, Sexuality and Women’s Studies The goal of this exploratory study was to evaluate risk and resiliency factors from the Deployment Risk and Resiliency Inventory (DRRI) in predicting post-deployment adjustment outcomes among police officers who served in …