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Articles 10171 - 10200 of 15019
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In Vitro Evaluation Of Mechanical Heart Valve Performance Using A Novel Test Chamber In An Automated Mock Circulatory Loop, Antonio Walker
In Vitro Evaluation Of Mechanical Heart Valve Performance Using A Novel Test Chamber In An Automated Mock Circulatory Loop, Antonio Walker
Theses and Dissertations
Valvular heart disease (VHD) continues to have significant effects on many people’s lives, with numbers expected to grow tremendously over the next few years. Individuals suffering from severe valvular heart disease usually require a heart valve transplant in order to restore the native valve’s vital unidirectional flow regulation. Therefore, artificial heart valve (AHV) research is of very high importance. Previous research studies have provided substantial input in the realm of AHV design relative to durability, thrombotic and hemolytic potential, and overall functionality. However, modifications continue to be warranted due to limitations in the accuracy and time efficiency of the in …
Effects Of Teaching Emotions To Students With High Functioning Autism Spectrum Disorders Through Picture Books, Jennifer M. Fletcher
Effects Of Teaching Emotions To Students With High Functioning Autism Spectrum Disorders Through Picture Books, Jennifer M. Fletcher
Theses and Dissertations
Individuals with autism spectrum disorders (ASD) struggle with identifying others' emotions, which impacts their ability to successfully interact in social situations. Because of the increasing number of children identified with ASD, effective techniques are needed to help children identify emotions in others. The use of technology is being researched as a way to help children with emotion identification. However, technology is not always available for teachers to use in classrooms, whereas picture books are much easier to access and have been successfully used to improve students' social skills. Picture books are naturally used in classroom, home, and therapy settings. This …
Samoan Speech Audiometry: Developing Word Recognition Materials For Native Speakers Of Samoan, Emma Lilian Kruger
Samoan Speech Audiometry: Developing Word Recognition Materials For Native Speakers Of Samoan, Emma Lilian Kruger
Theses and Dissertations
Hearing can be evaluated through the presentation of tones or speech. Speech audiometry determines an individual's speech recognition threshold and word recognition score. Traditionally these materials were developed using familiar, frequently used, monosyllabic words. Currently, there are various types of word recognition materials including those which use word lists, short half-lists, and materials which use sentences level stimuli with competing noise. Word recognition materials were first developed in Standard American English; today, materials are now readily available in many other languages. When possible, word recognition materials are developed digitally to standardize their presentation. Currently, no recorded word recognition materials are …
Adam10 Is A Critical Regulator Of B Cell Development, Antibody Production, And Myeloid-Derived Suppressor Cell Expansion: Effects Of B Cell-Specific Adam10 Deletion And Overexpression In Vivo., David Gibb
Theses and Dissertations
Proteolytic processing of transmembrane receptors and ligands can have dramatic effects on cell signaling and subsequent cellular responses. Previous studies demonstrated that a disintegrin and metalloproteinase 10 (ADAM10) may cleave numerous B cell-expressed receptors, including the low affinity IgE receptor (CD23). However, lethality of ADAM10-deficient embryos has limited examination of these cleavage events in lymphocytes. To investigate their role in B cell development and function, we generated B cell-specific ADAM10 knockout mice. Intriguingly, deletion prevented development of the entire marginal zone B cell (MZB) lineage. Further analysis revealed that ADAM10 is required for S2 cleavage of the Notch2 receptor and …
Aesthetic Self-Reliance: Emersonian Influence On American Art, Adrienne Lynn Rumsey
Aesthetic Self-Reliance: Emersonian Influence On American Art, Adrienne Lynn Rumsey
Theses and Dissertations
This essay is an examination of the influence of Ralph Waldo Emerson on the development of American art through his essays, specifically his writings on nature and self-reliance. Through emphasizing individual potential, Emerson also influenced the visual arts. Instead of following the required formula in Europe of attending certain ateliers and seeking prestigious patronage, American artists, namely the Luminists and the Ashcan School, sought to address the issues of their day and portray life as it existed around them. Each of these groups formed during periods of time when American society was shifting and the American identity was evolving. Through …
[Aura], Stephanie Benassi
[Aura], Stephanie Benassi
Theses and Dissertations
[AURA] is a collection of photographs of landscapes and objects that have been implicated in fringe beliefs, alternative narratives and the strange events that reside beyond the scope of our everyday experiences. These photographs represent the symbols used to describe phenomena and also concentrate on the areas surrounding the events. My investigation also examines how the affect of the landscape has contributed to the interpretations by those that witnessed it. As a photographic collection, [AURA] investigates issues related to truth, as well as the role of subjectivity versus objectivity in my photographic practice. By concentrating this discussion on issues of …
Role Of Ampk In The Upregulation Of Steroidogenic Acute Regulatory Protein In The Zona Fasciculata Of The Adrenal Cortex, Adam Wesley Dayton
Role Of Ampk In The Upregulation Of Steroidogenic Acute Regulatory Protein In The Zona Fasciculata Of The Adrenal Cortex, Adam Wesley Dayton
Theses and Dissertations
Cortisol is a glucocorticoid produced by the zona fasciculata (ZF) of the adrenal cortex. Traditionally, cortisol production and release was seen as being regulated strictly by adrenocorticotropic hormone (ACTH). While this is true of baseline cortisol levels and in response to acute mental stress, the picture is somewhat more complicated in other situations.Interleukin-6 (IL-6) contributes to the maintenance of cortisol levels in situations of prolonged immune or inflammatory stress. AMP activated protein kinase (AMPK) was investigated as a possible mediator of the action of IL-6 or as an independent actor in raising cortisol levels in response to hypoxemic or hypoglycemic …
Image Processing Algorithms For Diagnostic Analysis Of Microcirculation, Sumeyra Ummuhan Demir
Image Processing Algorithms For Diagnostic Analysis Of Microcirculation, Sumeyra Ummuhan Demir
Theses and Dissertations
Microcirculation has become a key factor for the study and assessment of tissue perfusion and oxygenation. Detection and assessment of the microvasculature using videomicroscopy from the oral mucosa provides a metric on the density of blood vessels in each single frame. Information pertaining to the density of these microvessels within a field of view can be used to quantitatively monitor and assess the changes occurring in tissue oxygenation and perfusion over time. Automated analysis of this information can be used for real-time diagnostic and therapeutic planning of a number of clinical applications including resuscitation. The objective of this study is …
Variable Palatability Of Quaking Aspen For Large Ungulate Herbivores, Patrice Alexa Nielson
Variable Palatability Of Quaking Aspen For Large Ungulate Herbivores, Patrice Alexa Nielson
Theses and Dissertations
Aspen is a key resource in the Rocky Mountain Region for wildlife forage and habitat, lumber products, scenery, and plays important roles in fire ecology and hydrological processes. There is evidence of aspen decline over much of the Intermountain West for approximately 100 years. In Dixie and Fishlake National Forests, UT, aspen distribution has decreased by nearly half. Causes of this decline are not well understood, although wildlife browsing by ungulates has been implicated as playing a major role. The objective of this research was to examine what soil or plant factors might be involved in wildlife browse choice in …
In Vivo Measurement Of Rat Skeletal Muscle Oxygen Consumption Following Brief Periods Of Ischemia With Reperfusion As Assessed By Phosphorescence Quenching Microscopy, William Nugent
Theses and Dissertations
Brief periods of skeletal muscle ischemia (ischemic pre-conditioning) alter cellular metabolism in a way that confers protection over subsequent ischemic episodes. The mechanisms behind this effect have been studied indirectly through assays for the byproducts of ATP synthesis and in vitro studies of cellular signaling cascades and ROS generation. There have been no direct, in vivo assessments of the changes in respiration during reperfusion. We employed phosphorescence quenching microscopy in conjunction with a flow-arrest technique to assess the influences of external, pressure-induced 1- to 10-min focal ischemia on interstitial oxygenation (PISFO2) and the consumption of oxygen (VO2) in spinotrapezius muscles …
Beta Galactosidose Activity Of Commercial Lactase Samples In Raw And Pasteurized Milk At Refrigerated Temperatures, Trenton W. Horner
Beta Galactosidose Activity Of Commercial Lactase Samples In Raw And Pasteurized Milk At Refrigerated Temperatures, Trenton W. Horner
Theses and Dissertations
Many consumers are unable to enjoy the benefits of milk, due to lactose-intolerance. Lactose-free milk is available, but at about 2 times the cost of regular milk or greater, it may be difficult for consumers to afford. The high cost of lactose-free milk is in part due to the added cost of the lactose hydrolysis process. Hydrolysis at refrigerated temperatures, possibly in the bulk tank or package, could increase the flexibility of the process, and potentially reduce the cost. A rapid β-galactosidase assay was used to determine the relative activity of commercially available lactase samples at different temperatures. Four enzymes …
Canopy Disturbance And Reproduction In Cornus Florida L., Daniel Carr
Canopy Disturbance And Reproduction In Cornus Florida L., Daniel Carr
Theses and Dissertations
This study examined aspects of local reproductive variation in the flowering dogwood (Cornus florida L.) coincident with recent differences in primary canopy architecture. The dogwood trees in this study were impacted by a hurricane that created numerous treefall gaps, which created fine scale heterogeneity in the primary canopy. Fine scale disturbances in a forest can result in changes for multiple members of the forest community, including the reproductive responses of the trees and interspecific pollination mutualisms. Previously determined differences in offspring genetic structure suggested that pollen movement among genetically unstructured maternal individuals was significantly impacted between open, or disturbed, canopy …
A Mechanistic Study Of Strain Rate Sensitivity And High Rate Property Of Tendon, John Steeneck Clemmer
A Mechanistic Study Of Strain Rate Sensitivity And High Rate Property Of Tendon, John Steeneck Clemmer
Theses and Dissertations
The ultrastructural mechanism for strain rate sensitivity of collagenous tissue has not been well studied at the collagen fibril level. The objective is to reveal the mechanistic contribution of the collagen fibril to strain rate sensitivity. Collagen fibrils underwent significantly greater fibril strain relative to global tissue strain at higher strain rates. A better understanding of tendon mechanisms at lower hierarchical levels would help establish a basis for future development of constitutive models and assist in tissue replacement design. High rate mechanical property of tendon was also studied. Tendon was compressed under high strain rate (550 /s) using a polycarbonate …
Accuracy Of Estimating Age And Antler Size Of Photographed Deer, Jeremy J. Flinn
Accuracy Of Estimating Age And Antler Size Of Photographed Deer, Jeremy J. Flinn
Theses and Dissertations
Objective and accurate techniques are needed to estimate age and antler size of live white-tailed deer (Odocoileus virginianus), because these parameters are essential to many white-tailed deer management strategies. I developed and evaluated accuracy of methods for estimating age and antler size from photographs of live, male white-tailed deer using Geographic Information Systems (GIS). I estimated size of photographed, known-score mounted antlers accurately using a fixed-scale object and photographed, live deer using anatomical features. I determined if a series of morphometric ratios could be used to predict age of deer from photographs using a dichotomous key procedure. Mean percentage error …
An Applied Investigation Of Kenaf-Based Fiber/Polymer Composites As Potential Lightweight Materials For Automotive Components, Yicheng Du
Theses and Dissertations
Natural fibers have the potential to replace glass fibers in fiber-reinforced composite applications. However, the natural fibers’ intrinsic properties cause these issues: 1) the mechanical property variation; 2) moisture uptake by natural fibers and their composites; 3) lack of sound, cost-effective, environmentriendly fiber-matrix compounding processes; 4) incompatibility between natural fibers and polymer matrices; and 5) low heat-resistance of natural fibers and their composites. This dissertation systematically studied the use of kenaf bast fiber bundles, obtained via a mechanical retting method, as a light-weight reinforcement material for fiber-reinforced thermoset polymer composites for automotive applications. Kenaf bast fiber bundle tensile properties were …
Characterization Of Arabidopsis Thaliana Mutants Lacking A Jumonji Domain Containing Histone Demethylase And A Set Domain Containing Histone Methyl Transferase, Swetha Mamidi Reddy
Characterization Of Arabidopsis Thaliana Mutants Lacking A Jumonji Domain Containing Histone Demethylase And A Set Domain Containing Histone Methyl Transferase, Swetha Mamidi Reddy
Theses and Dissertations
Condensation of chromatin and alteration of chemical groups in the proteins around which the DNA is wrapped play major role in regulation of transcription. Histones are basic proteins rich in arginine and lysine residues which form the nucleosomal core. Histone modifications like acetylation, methylation, phosphorylation, etc. have broadened the horizon for researchers to study epigenetics more in detail. Histone methyl transferases and histone demethyl transferases are enzymes which add or remove methyl groups on histone lysine and arginine residues respectively. In this study a jumonji domain containing putative histone demethyltransferase has been shown to be responsible in controlling flowering phenotype …
Characterization Of The Occ Gene Cluster Required For The Production Of Antifungal Compound Occidiofungion In Burkholderia Contaminans Strain Ms14, Ganyu Gu
Theses and Dissertations
Strain MS14, exhibiting antifungal activity, was classified to belong to Burkholderia contaminans. Occidiofungin produced by strain MS14 is an octapeptide dedicated to a broad range of antifungal activities of the bacterium. The 58.2-kb genomic fragment containing 18 open reading frames (ORFs), named occidiofungin (occ) gene cluster, is required for occidiofungin production. Putative proteins encoded by five nonribosomal peptide synthetase genes (occA – occE) of the gene cluster were predicted to contain the catalytic modules responsible for the biosynthesis of occidiofungin. Transcription of all the ORFs identified in the region except ORF1 and ORF16 was regulated by both ambR1 and ambR2, …
Design And Analysis Of Static Windrow Piles For In-House Broiler Litter Composting, Amy M. Schmidt
Design And Analysis Of Static Windrow Piles For In-House Broiler Litter Composting, Amy M. Schmidt
Theses and Dissertations
In-house windrow composting of broiler litter has been studied to reduce microbial populations between flocks. Published time-temperature goals are used to determine the success of the composting process for microbial reductions. Spatial and temporal density of temperature measurement can influence the ability to determine what portion of a windrow pile has achieved specified time-temperature goals. Based on this motivation, an investigation of the heating profile in windrowed litter and the identification of the effects of spatial and temporal sampling densities on the prediction of the heating profile in windrowed broiler litter were executed. Likewise, an investigation of the effects of …
Effects Of Aspirin, Meloxicam, Deracoxib, And Carprofen On Platelet Function In Dogs, Kathleen Brannon Mullins
Effects Of Aspirin, Meloxicam, Deracoxib, And Carprofen On Platelet Function In Dogs, Kathleen Brannon Mullins
Theses and Dissertations
Little research has been published evaluating the effect of non-steroidal antiinflammatory drugs (NSAIDs) on platelet function in dogs. The effects of aspirin and cyclooxygenase-2 (COX-2) selective NSAIDS on platelet function were evaluated. Eight dogs received aspirin 10 mg/kg PO every 12 hours for 10 days, and then were randomly assigned to 4 groups, with each group receiving one of the following PO for 7 days in a crossover study design: carprofen 2.2 mg/kg every 12 hours, carprofen 4.4 mg/kg every 24 hours, meloxicam 0.2 mg/kg every 24 hours first day then 0.1 mg/kg every 24 hours for 6 days, or …
Investigation Of High Rate Mechanical Properties And Damage Evolution In Porcine Liver Tissue, Joseph Chen
Investigation Of High Rate Mechanical Properties And Damage Evolution In Porcine Liver Tissue, Joseph Chen
Theses and Dissertations
Each year, 6.4 million automobile accidents account for approximately 40,000 deaths in the United States. With increasing requirements for automobile safety, computational models capable of simulating organ deformation/ injury during high impact scenarios would be extremely valuable for optimizing safety measures. Accurate experimental data is essential for the accuracy of the models; however, there has been a sparse investigation into high-strain biomechanics which is necessary to address organ/tissue response in high impact scenarios. Damage threshold criterion and damage evolution are other areas that have not been well studied. In vehicular accidents, damage to the liver is the most common cause …
Damage And Failure In The Carotid Artery: A Mechanistic Approach, Lauren Beatty Priddy
Damage And Failure In The Carotid Artery: A Mechanistic Approach, Lauren Beatty Priddy
Theses and Dissertations
Blunt carotid artery injury (BCAI), resulting primarily from automobile accidents, is a major contributor to the high mortality and morbidity rates associated with carotid artery dissection. More work is needed to characterize carotid artery injury mechanisms, quantify stages of damage, and elucidate failure modalities as a result of this type of injury. The present study examines the structure and mechanics of the carotid artery in the circumferential and axial directions by employing uniaxial tensile testing, high speed videography, interruption testing, scanning electron microscopy (SEM), histological analysis, real-time environmental SEM assessment, and atomic force microscopy (AFM). Results are as follows: (i) …
Depuration As A Method To Reduce Vibrio Vulnificus Populations In Live Crassostrea Virginica Oysters, Oleksandr S. Tokarskyy
Depuration As A Method To Reduce Vibrio Vulnificus Populations In Live Crassostrea Virginica Oysters, Oleksandr S. Tokarskyy
Theses and Dissertations
Vibrio vulnificus is a foodborne bacterial pathogen associated with raw oyster consumption. Shellfish depuration for 48 hours is a dynamic process where coliform bacteria are purged; however, this process is ineffective against V. vulnificus. The current study investigated the use of prolonged two-week depuration on V. vulnificus populations in Gulf Coast oysters. The study evaluated the impact of prolonged depuration on V. vulnificus fatty acid profile change and the ability to survive in simulated gastric fluid. Oyster depuration in seawater (10 or 22oC, 14 days) reduced V. vulnificus counts, but not to non-detectable level, indicating close ecological relationship between the …
The Effects Of Dietary Amino Acid Density In Broiler Feed On Carcass Characteristics And Meat Quality, Reid Alexander Lilly
The Effects Of Dietary Amino Acid Density In Broiler Feed On Carcass Characteristics And Meat Quality, Reid Alexander Lilly
Theses and Dissertations
Research was conducted to evaluate the effect of dietary amino acid (AA) density (Deficient (D), Low (L), High (H), and Excessive (E)) on broiler breast and thigh meat quality. As expected, the feed conversion improved (P<0.05) as AA density increased. No differences (P>0.05) existed among treatments with regard to final pH, cooking loss, shear force, brine absorption proximate analysis, and average consumer acceptability of breast meat. The D AA diet yielded meat with less (P<0.05) moisture, less protein (P<0.05) and more fat (P<0.05) than all other treatments. Increasing AA density in the diet led to increased (P<0.05) concentrations of linoleic and linolenic acid in the thigh meat from the H and E treatments, thus making it more susceptible to oxidation (P<0.05) in comparison to the D and L treatments. Overall, data revealed that all four AA diets yielded high-quality breast and thigh meat with minimal product differences.
The Relationship Between Conduct Problems And Attention Deficit Hyperactivity Disorder In Adolescent Psychopathy, Cary Stacy Smith
The Relationship Between Conduct Problems And Attention Deficit Hyperactivity Disorder In Adolescent Psychopathy, Cary Stacy Smith
Theses and Dissertations
The study of adolescent psychopathy has grown from being a fringe element in psychology to a mainstream topic for research. One issue that divides scholars centers on the relationship between conduct problems and attention-deficit hyperactivity disorder (ADHD) and their relationship to adolescent psychopathy. Some state the former factor has the most crucial relationship while other scholars categorically disagree, claiming that ADHD is the strongest. The majority of adolescents assessed for adolescent psychopathy are residents at state training schools; however, many of the behaviors associated with psychopathy are seen in students assigned to their district’s alternative educational setting. In order to …
Protein Markers In Angus Bull Spermatozoa For Fertility, Xiaojun Wang
Protein Markers In Angus Bull Spermatozoa For Fertility, Xiaojun Wang
Theses and Dissertations
In the field of mammalian reproduction, the success rate of fertilization largely relies on spermatozoa fertility potential. Total proteins change to a large degree during gametogenesis to activate gametes. There are some techniques that are most popular for proteomic studies of fertilization, including SDS-PAGE, 2D-DIGE, Western Blotting and Immunocytochemistry, as well as Mass Spectrometry. Proteins and their cofactors play important roles at different stages of gametogenesis, fertilization and embryo development. However, insufficiencies in the construction mode of fertility hinder the techniques in determination the sperm fertility. This study focused on identifying and tracking crucial proteins for fertility based on comparison …
Seasonal Variation In The Number Of Dogs And Cats Entering Four Animal Shelters In Mississippi And The Characterisitics [I.E. Characteristics] Influencing Their Adoption, Sarah Elizabeth Lefebvre
Seasonal Variation In The Number Of Dogs And Cats Entering Four Animal Shelters In Mississippi And The Characterisitics [I.E. Characteristics] Influencing Their Adoption, Sarah Elizabeth Lefebvre
Theses and Dissertations
The pet overpopulation problem is a multiactorial problem that many organizations such as animal shelters attempt to manage. Many studies have focused on the reasons animals are relinquished by their owners but few have also looked at the characteristics that may influence adoption. Identifying which characteristics that influence adoption may help shelters provide more detailed adoption programs based on their dog and cat profile. Increases in the number of dogs and cats entering animal shelters during the spring and summer month is a perception among shelter staff. Investigating the seasonal trends in the number of animals entering a shelter may …
Skin From Horses With Hereditary Equine Regional Dermal Asthenia (Herda) Contains Collagen Crosslinking Patterns That Are Associated With Reduced Tensile Strength, Ashley Arwen Hill
Skin From Horses With Hereditary Equine Regional Dermal Asthenia (Herda) Contains Collagen Crosslinking Patterns That Are Associated With Reduced Tensile Strength, Ashley Arwen Hill
Theses and Dissertations
Hereditary equine regional dermal asthenia (HERDA) is a recessive connective tissue disorder of Quarter Horse lineages. This study correlates previously identified decreases in skin tensile strength in HERDA with abnormal dermal collagen cross linking patterns that are also identified in urine from HERDA horses. Dermal collagen from HERDA horses has significantly less pyridinoline and significantly more deoxypyridinoline than control or carriers. Concentrations of hydroxylysine, the rate limiting substrate for these crosslinks were significantly lower in HERDA versus control and carriers. These characteristics of HERDA skin parallel humans with a similar syndrome of skin fragility, Ehlers Danlos Syndrome TypeVIA. This is …
Novel Type Engineered Structural Beams From Pine Lumber, Maisaa Kakeh
Novel Type Engineered Structural Beams From Pine Lumber, Maisaa Kakeh
Theses and Dissertations
The intersection of decreasing resource size and increasing population and its associated demand creates a pressing need to develop products that act as alternatives to solid sawn lumber. Engineered composite lumber is one such alternative. The product described herein utilizes a modified form of sawn lumber as the raw material. The objective of this research was to manufacture, mechanically test, and evaluate a novel type of engineered lumber. Non destructive evaluation of raw materials and finished beams, and final mechanical testing to determine mean strength and stiffness values as per ASTM 5456 were used. The mechanical property data was converted …
Nutrient Utilization By And Diet Preference Of American White Pelicans When Offered Diets Of Channel Catfish And (Or) Grass Carp, Treena Lee Ferguson
Nutrient Utilization By And Diet Preference Of American White Pelicans When Offered Diets Of Channel Catfish And (Or) Grass Carp, Treena Lee Ferguson
Theses and Dissertations
Twelve pelicans captured in northeast Mississippi were used for a 7 day metabolism trial followed by a 2 day preference trial and a trial to evaluate the effect of consuming plastic tags. In the metabolism trial, pelicans were allotted to one of three treatment diets (4 birds/diet): catfish only, carp only or both (50 % catfish and 50% carp). Pelicans consuming the catfish only diet metabolized less dry matter, organic matter and energy than those consuming only carp or both. Four pelicans were used to determine preference for carp or catfish. Pelicans ate more (P = 0.001) carp (89 % …
On The Design-Build Of Small Pavilions, Agrippa Spence Kellum
On The Design-Build Of Small Pavilions, Agrippa Spence Kellum
Theses and Dissertations
Design-build is the process whereby a project is constructed by the same entity that designed it. Detailed narratives are provided for the collaborative, integrated designbuild of two small, relatively contemporary pavilions. The first was constructed as part of a design-build workshop taught by Steve Badanes, director of the Neighborhood Design/Build Studio at the University of Washington Department of Architecture and founder of the international architecture firm The Jersey Devil. The second, a multi-use pavilion on the site of a former junkyard, was implemented as a local volunteer community service project using Badanes' method. A third proposal is also described; an …