Digital Commons Network^™

Characterization Of Monoclonal Antibodies Against Digoxin, Susan K. Alexandrovich

Theses

Five antibodies directed against digoxin were grown and characterized. Two separation techniques were tested to find the better method of separating bound the free fractions of ligand after competitive reactions with the antibodies. Charcoal separation was chosen. The antibodies were analyzed for affinity constant by the Scatchard Analysis. Cross reactivity data for two of the antibodies were collected. Four of the antibodies have satisfactory affinity constants for use in a digoxin assay. Cross reactivity studies showed varying amounts of cross reactivity with digoxin metabolites, but none with the steroids and lipid tested.

Software Estimating: A Description And Analysis Of Current Methodologies With Recommendations On Appropriate Techniques For Estimating Rit Research Corporation Software Projects, Norma Armstrong

Theses

This thesis investigated, described, and analyzed six current software estimation methodologies. Included were Boehm's COCOMO, Esterling's Work Productivity Model, Putnam's Life Cycle Model and Albrecht's Function Point Determination. An implementation strategy for software estimation within RIT Research Corporation, a consulting firm, has been developed, based on this analysis. This strategy attempts to satisfy key needs and problems encountered by RIT Research estimators, while providing cost effective, accurate estimates.

Signature File Access Methodologies For Text Retrieval: A Literature Review With Additional Test Cases, Karen Caviglia

Theses

Signature files are extremely compressed versions of text files which can be used as access or index files to facilitate searching documents for text strings. These access files, or signatures, are generated by storing "hashed" codes for individual words. Given the possible generation of similar codes in the hashing or storing process, the primary concern in researching signature files is to determine the accuracy of retrieving information. Inaccuracy is always represented by the false signaling of the presence of a text string. Two suggested ways to alter false drop rates are: 1) to determine if either of the two methologies …

Investigation Of Steady Incompressible Flows In The Vicinity Of An Airfoil, Sivaraj Kailasapathy

Theses

O-type body-fitted coordinate systems are numerically generated about NACA0012 and NACA4412 airfoils. These coordinate systems are used to effect a coordinate transformation from the physical plane to a rectangular transformed plane. The software developed also has a coordinate contraction capability. Plots of uncontracted and contracted coordinate systems are presented.

The nonconservative, velocity-pressure formulation of the two-dimensional, steady-state Euler equations are transformed to the rectangular plane. The boundary conditions at the airfoil are determined by the source-panel method, following which, the explicit finite difference form of the transformed Euler equations are solved using a space-marching scheme. Non-lifting potential flow solutions are …

A Multipurpose Test Mask For Exposure Tool Characterization, Brian Benamati

Theses

Of the many facets of integrated circuit fabrication, photolithography may very well be the most important due to the number of levels required for the fabrication of sophisticated devices. Therefore it is imperative to understand the performance capabilities of an exposure tool and identify its inherent limitations. Many methods have been developed which concentrate specifically on evaluating resolution, critical dimensions or registration. Often test patterns exist which vary widely for applications with respect to steppers, IX scanning projection aligners and other IX exposure equipment. The following work is focused on the requirements of evaluating and optimizing all aspects of performance …

High Temperature Reactions Of 1,2-Dichloroethane With Water Vapor In A Tubular Reactor, Charles E. Anderson

Theses

This study examines the reaction of l,2-dichloroethane with water vapor. The linear-flow method is utilized, assuming plug flow without axial diffusion. Normal operation is at atmospheric pressure and the reactor is a quartz tube in a thermal region 45 cm in length. Two reactor diameters of 0.4 cm and l.05 cm are used. Water and l,2-dichloroethane enter the system in liquid phase via syringe pumps. After vaporizing in heated tubing, they are combined with argon, the reactor carrier gas. The molar ratio of water to l,2-dichloroethane is 55:l and varied residence times are achieved by changing the argon flowrate. Reactor …

A Cost And Performance Analysis Of The Three Electronic Communication Systems Currently In Use In The Printing And Publishing Industry, Susan Richards

Theses

This study describes and evaluates the three electronic graphic communication systems presently used by the printing and publishing industry. The author has selected generic system names for each of the systems. These are: System 1: Page Facsimile System 2: Character-Encoding System 3: Pixel Density-Map Page Facsimile systems are primarily used by newspaper publishers. The Character-Encoding and Pixel Density-Map systems are alternate methods primarily used by newsweekly magazine publishers. All three communication systems offer the user a means of transmitting editorial, and in some cases advertising pages, to remote printing facilities for manufacturing and distribution. Each electronic graphic communication system is …

An Exploration Of Triarylmethane Leucohydroxides, Mahin Sadrai

Theses

To explore the possibilities of the potential use of photochromism of triarylmethane leucohydroxides and leucobisulfites , five leucohydroxides (see Table [5]) and five leucobisulfites were synthesized and two leucohydroxides and one leucobisulfite were investigated in a variety of solvents with different Brownstein Coefficients. Malachite green leucohydroxide and crystal violet leucohydroxide showed opposite behavior in the same basic solutions, while both of them were dramati cally affected by the change in solutions basicity. Photodegradation induced by repeated exposure (fatigue) manifested itself in the form of lower photo -induced optical density, with a constant halflife in malachite green leucohydroxide and in the …

The Computer As A Fine Art Tool, Edward Kinney

Theses

Not Included

Jmsl - A Language Derived From Apl, John Mark Smeenk

Theses

A new AFL-derived language called JMSL is presented which rnodifies seven aspects of APL so that many current and potential APL users could benefit from a language which is easier to learn, read, write, and maintain. JMSL uses ASCII tokens instead of APL symbols to remedy interfacing, extensibility, and readability problems with APL. JMSL revises and extends APL built-in capabilities to provide greater expression and improved symbol-meaning correspondence. JMSL includes a new notation for nested arrays (a powerful data structure which combines the array processing of APL with the tree processing of LISP). JMSL provides hierarchical directories (similar to PASCAL …

Experimental Study Of Rectangular Reinforced Concrete Members Under Combined Biaxial Bending And Tension, Naresh B. Patel

Theses

In practice it is a very common case to have a column subjected to combined effects of axial tension and biaxial bending moments and very few efforts are done to get good design approach for such special members.

So for this purpose, experiments were carried out on rectangular shapecolumns. Rectangular shaped columns were casted in homogeneous with brackets - one on each end and at connections haunches were provided to avoid the possible end failure. The overall shape of this configuration was "H" shape. Two hydraulic jacks were used; one on either side of the columns and thus column section …

Biorhythms And Industrial Injuries, James Vincent Detitta

Theses

The purpose of this study is to determine whether or not a relationship exists between the time of an industrial injury and a specific position on the biorhythm scale known as a critical day.

Ninety-six employees who worked at the E. I. du Pont de Nemours Plant in Parlin, New Jersey served as a test group during 1980. In order to determine if a relationship did exist, the subjects' biorhythmic cycles for 1980 were charted and then their injury performance was monitored during that year to see if the injury date corresponded with a critical day. An additional test was …

Gas-Phase Reaction Of 1,2-Dichloroethane With Hydrogen In A Tubular Flow Reactor, Wei-Lian Lee

Theses

We have studied the reaction of 1,2-dichloroethane with H₂ in three tubular flow reactors of different diameters at atmospheric pressure in the temperature range of 550° C to 1000°C. The kinetic parameters and product distribution were experimentally determined for each size reactor. The wall and bulk reaction rate constants were decoupled via analysis of three different surface to volume reaction data.

The experimental reactor was an isothermal tubular flow reactor that operated within the domain of plug flow region. The reaction was found to follow first-order kinetics with respect to 1,2-dichloroethane when in the presence of excess hydrogen. The …

A New Density-Dependent Mixing Rule For Equations Of State, Theodore John Shatynski

Theses

A general procedure for the development of density-dependent mixing rules is demonstrated. This method is used to obtain a density-dependent local-composition mixing rule based on an extention of the work of Knox et al (1984). The resulting expression is tested with the Soave-Redlich-Kwong equation of state. Results for normal and cryogenic vapor-liquid systems for both one-parameter and three-parameter versions of the mixing rule are compared with results using the classical mixing rules.

Effect Of Center Of Gravity Location On Optimum Performance Of Random Vibratory Vehicle Suspension, Daniel Mahar

Theses

This study provides the analysis for the optimal design of a conventional vehicle suspension system, consisting of a sprung mass (vehicle body) and two unsprung masses (wheel frame), accentuated by the implementation of a damped absorber to the unsprung masses. Further, the effect of the c.g. (center of gravity) location of the vehicle body is investigated. A two dimensional, four degrees of freedom linear model is chosen. Randomly profiled terrain is assumed to impart hyperbolically distributed stationary vertical random displacements to the front and rear wheels. For generalization, nondimensional design parameters are selected. Criteria for optimization include the tire-terrain normal …

Tests On Square Reinforced Concrete Members Under Combined Biaxial Bending And Tension, Bhadresh Shah

Theses

The research reported herein studies the ultimate strength behavior for square-shaped reinforced concrete short columns under combined biaxial bending and tension that is a common design problem. The present ACI building code (ACI 318-83) (1) and design hand book (2) do not offer an insight into the determination of strength and ductility behavior of biaxially loaded reinforced concrete columns. A design equation developed by Hsu (3,4,5 ) to study the ultimate strength behavior and failure surfaces for members under these combined action was used and the computed results were compared with the present analytical results and experimental results for square-shaped …

Analyze3d, A Structural Analysis Program Employing Membrane And Solid Finite Elements, James Mendham Gathercole

Theses

The purpose of this thesis is to describe the addition of an 8 and 20-node isoparametric brick element to the finite element program ANALYZE, permitting three-dimensional analysis. The reason for the addition is that even though Analyze is a relatively simple program, its simplicity makes it a good educational tool for finite element courses. The added brick element expands the use of the program for educational purposes.

In its original form, Analyze is a finite element package for static structural analysis developed at Wright Patterson Air Force Base. The program consists of four finite elements: (1) bar, (2) membrane triangle, …

An Agreeable Truth: Facts And Faith In Nineteenth Century Photography, David Wooters

Theses

Not Included

Muscle In Motion: Four Of The Most Common Overuse Injuries Of The Bicyclist, Carol France Kalafatic

Theses

Not Included

A Party To All Secrets, Jacqueline Gentile

Theses

None provided.

Graphic Design Archive On Videodisc Marketing And Communication Programs, John Benton Malinoski

Theses

None provided.

Structuralism, Charles N. Smith

Theses

Structuralism is an interdisciplinary form of modern painting that suggests the illusion of movement and growth through the conscious manipulation of flat colors and abstract geometric forms. The practice of Structuralism involves more than a grasp of the craft of painting. The artist is required to understand and practice the laws of proportion as founded by the early Egyptians and Greeks. He must have an understanding of modern color theory and he must master and practice the laws of visual perception as stated by the Gestalt psychologist, David Katz.

I have tried to recreate the chronological development of Structuralism by …

A Music Program Assessment Instrument Based On Widely Held Music Education Goals, Jerry Arana

Theses

The students, parents and teachers of Christian Brothers College High School were surveyed to determine their degree of satisfaction with the music program there. The survey was compiled from literature regarding music education.

Data were gathered by devising and administering an assessment instrument utilizing a set of 15 goals as advocated by leaders in music education. The sample consisted of 69 music students, 66 of their parents, and 32 faculty members from Christian Brothers College High School .

It was hypothesized that :

1. There would be no difference between the mean scores of parents, students and faculty .

2. There would …

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Steady State Stress Distribution And Force Transmissibility Of A Rotating Disk Of Variable Thickness, John Ole Hansen

Theses

The governing equations of the transverse vibration of a spinning disk of varying thickness are derived and solved using numerical integration techniques. A clamped-free rotating annular disk driven at the outer edge with sinusoidally varying force is considered for analysis. Representative graphs showing the stress distribution and the frequency dependence of the force transmissibility of the disk are presented. Results obtained in this paper are compared as applicable to results of previous investigations.

Proper Spaces, Karen Wollins

Theses

Not Included

Cmos Analog Transmission Gate Design, Cynthia S. Bell

Theses

CMOS technology has provided an integrated circuit equivalent for the conventional electromechanical switch: the transmission gate. CMOS analog transmission gates degrade signals passed through them with noise due to gate clock feedthrough transients. A SPICE parameter model for the Eastman Kodak CMOS process has been developed and timing requirements for feedthrough cancellation in typically structured transmission gate devices have been studied. An alternate device structure for improved performance is proposed.

A Semiotic Approach To The Study Of Symbols, Susan Dosick

Theses

None provided.

An Inventory Model For The Specialty Chemical Industry, Paul Murchison

Theses

The specialty chemical industry is a unique segment of the chemical industry. This industry produces chemical intermediate products for the pharmaceutical, agricultural, cosmetics, and other chemically related industries. Most of the products that are produced are covered by patents or involve proprietary know—how. The specialty chemical products are a minor part of a total formulation but contribute unique properties to the end product. This feature of specialty chemicals gives the manufacturer unusual pricing power compared to producers of commodity chemicals. This industry has proven to be very competitive, profitable and in the forefront of the present automation revolution over the …

Technology Transfer Between Developed And Developing Countries, Tenny Oghogho Ogbomo

Theses

The problems arising from technology transfer, in general, are not new. The problems of the East-West technology transfer, for example, are based on the risk that such transfers will enhance the military capability, or at least the military potential, of the trading partner. In the case of United States trade with the Soviet Union, it can be said that any accretion in the Soviet military capacity weighs against the United States in an overall world-wide balance of power. The restrictions and/or prohibition of such transfer of technology are problems themselves.

The North-South technology transfer, in other words, the technology transfer …

On-Line Analysis Of Highly Coherent Brain Activity During Transcendental Meditation And Automated Biofeedback, Deepak Dinkerrai Rawal

Theses

Occurance of highly coherent brain activity (EEG) specific to the meditation has been reported in the literature. The present thesis is an effort to look into the mechanics of meditation using the recent technique of analysis of high coherence in the EEG. Based on previous work, reporting increased EEG coherence during practice of Transcendental Meditation, a closed loop model and hypothesis is proposed using biofeedback to close the loop. The hypothesis proposes that very high coherence in the EEG is a very significant neurophysiological parameter, reflecting instantaneous quality of meditation in the form of an average high coherence above threshold. …