Digital Commons Network^™

Material Engagement Theory And Extensive Enactivism Within The 4e Cognitive Debate: A Phenomenological Approach To Material Agency And Application To Current Technology, Israel Quirit

Theses

4E Cognition is a fairly new field of study within cognitive science, cognitive psychology, and cognitive philosophy. The various approaches to cognition namely embodied, embedded, extended and enacted cognition; provide multi-faceted approaches to cognition. A common claim of these approaches is that cognition may have various contributing factors such as the role of the brain, body and its environments. Thus challenges the traditional idea that cognition exists purely mentally within the confines of the brain and skull. However, even within the 4E Cognition family, some nuanced arguments are hotly debated, particularly among the proponents of Embedded Theories (EmT) and Extended …

Role Of Mkp-2 In Glucose Metabolism And Stress-Induced Insulin Resistance, Yanthrawaduge Savanie Sulakshana Devsirini Fernando

Theses

The function of MKP-2 in metabolism and metabolic diseases remains largely unknown. In obese conditions mitogen-activated protein kinase (MAPK) pathway get dysfunctional and MAP kinase phosphatases (MKPs) play major roles in regulating the activities of MAPKs. We examined the regulation of MKP-2 expression in vivo, under physiological and pathological conditions, in the liver and other insulin responsive tissues using diet-induced obesity models using novel MKP-2 knockout mice. Also, we examined MKP-2 expression in vitro using insulin sensitive cell lines. We found that MKP-2 is expressed in insulin-sensitive tissues/cells and overexpression may delay muscle cell differentiation. Our novel data demonstrate that …

Experimental Measurements Of The Wing Deformation And Force Production Of Real Monarch Butterfly Wings, Timothy Daniel Robert Morris

Theses

Monarch Butterflies are capable of flying over 4000 kilometers as they migrate from North America to Mexico. In regard to the aerodynamic mechanisms that drive this extensive flight, little is known. This thesis is motivated by the hypothesis that their flapping wing flight is enhanced by fluid-structure interactions. The objective was to quantify the aeroelastic performance of a real monarch butterfly wing at flapping amplitudes near monarch free-flight amplitudes. The performance of the real monarch butterfly wing was tested by measuring the wing motion and lift at a flapping amplitude of 55° and frequencies between 7.0 and 14.4 Hz. The …

Elucidation Of Multi-Origin Inula Helenium L. For Antimicrobial Activity And Heavy Metal Profiling As An Exemplar For The Use And Regulation Of Plants As Antibiotics., Ciara Ruth Kenny

Theses

An impending post-antibiotic era looms, thus new sources of therapeutic chemical entities are crucial to sustain effective antimicrobial chemotherapy worldwide. Plant natural products are a source of accessible, structurally diverse compounds that provide therapeutic potential. The pharmacological applications of plants in medicine can be guided by the attestation of traditional use or the application of this knowledge to uncover new leads in the drug discovery process. The range of modified in vitro methods commonly used to investigate preclinical antimicrobial efficacy of plant-derived natural products, and the associated limitations and challenges in the provision of new antimicrobial drugs from plants is …

Evaluation Of A ‘Well-Elderly’ Physical Activity Programme, Robert Purcell

Theses

Both in Ireland and internationally people are living longer and there is an increasing proportion of older adults in the population (Clark 2020). As such, the maintenance of health and physical function for older adults is of critical importance. Physical activity is widely acknowledged as being crucial for the maintenance of positive health, particularly for older adults (Spartano et al., 2019). Research has suggested that physical activity programmes are an effective means of engaging older adults in physical activity for the promotion of positive health (Sherrington et al., 2017). The central aim of this research project was to explore the …

Cold Storage Work And Cold Protective Gloves – A Review, Daena Charles

Theses

The rise of e-commerce and the increasing demand for online grocery shopping and delivery has prompted the growth of warehouse workers subjected to cold temperature working conditions. To ensure food safety and the preservation of inventory, majority of these e-grocery warehouses are cold storage with temperatures from 10°C to -23°C. Exposure to such cold working environments can have effects on the workers comfort, performance and health. As the demand for workers in cold temperature environments increases, it is important to understand how this environment affects the workers and the challenges it may present.

This review evaluates how working in cold …

Accelerating Transitive Closure Of Large-Scale Sparse Graphs, Sanyamee Milindkumar Patel

Theses

Finding the transitive closure of a graph is a fundamental graph problem where another graph is obtained in which an edge exists between two nodes if and only if there is a path in our graph from one node to the other. The reachability matrix of a graph is its transitive closure. This thesis describes a novel approach that uses anti-sections to obtain the transitive closure of a graph. It also examines its advantages when implemented in parallel on a CPU using the Hornet graph data structure.

Graph representations of real-world systems are typically sparse in nature due to lesser …

Human Activity Recognition Using Wearable Sensors: A Deep Learning Approach, Jialun Xue

Theses

In the past decades, Human Activity Recognition (HAR) grabbed considerable research attentions from a wide range of pattern recognition and human–computer interaction researchers due to its prominent applications such as smart home health care. The wealth of information requires efficient classification and analysis methods. Deep learning represents a promising technique for large-scale data analytics. There are various ways of using different sensors for human activity recognition in a smartly controlled environment. Among them, physical human activity recognition through wearable sensors provides valuable information about an individual’s degree of functional ability and lifestyle. There is abundant research that works upon real …

Impact Of The Emergency Use Authorization On Ventilator Innovation, Krista Stanislow

Theses

Innovation in the medical device industry is crucial to continuously improve the health and wellbeing of society. The U.S. Food and Drug Administration (FDA) is responsible for ensuring the safety and effectiveness of medical devices on the market while balancing the need for continuous innovation. One way the FDA has tried to support innovation is through the development of the 510(k) pathway, which does not require clinical testing as the safety of the device is determined based on a predicate device. Many companies choose to develop products that can obtain approval through the 510(k) pathway. While the 510(k) pathway is …

The Role And Mechanism Of Cytochrome P450 1b1 On The Development Of Atherosclerosis; Producing The Animation For Visual Communication And Education., Joon Yeol Ryu

Theses

A large number of people are suffering from cardiovascular disease and losing their lives because of it. Atherosclerosis, a classic example of cardiovascular disease, is related to cytochrome p450 1B1 and other molecules in the development of the disease. Educational materials for patients and students on this topic are expected.

Advantage, role and effectiveness of three-dimensional (3D) animation as a communication tool in biomedical science research and education have been proved. Therefore, 3D animation is a suitable medium to create visual material for atherosclerosis and related subject.

Autodesk Maya 3D computer graphics software used for animation from modeling to animating …

Combating Human Trafficking: Assessing Justice Systems Response, Carly Stephens

Theses

The purpose of this thesis was to examine and assess justice system efforts in combating human trafficking; more specifically sex trafficking. The goal was to understand how efforts of combating human trafficking started, how they progressed, and to explore where efforts remain at this time. Additionally, the goal was to identify and understand what is working in law enforcement, human trafficking courts, and policy. This included identifying issues such as disparity in law enforcement reporting, lack of recognition of sex trafficking, and outdated policies. To assess these issues, this project utilized human trafficking data available through the FBI Uniform Crime …

Fda Regulation Impact On Early Stage Medical Device Innovation In Academia, Keyana Fariello

Theses

The commercialization of medical products at the university level is a multilayered and challenging process. One barrier to commercialization is the difficulty of meeting Food and Drug Administration (FDA) regulatory requirements. Regulations and standards are undoubtedly necessary to maintain the highest product safety levels, but it creates many obstacles. This paper will analyze how researchers involved with early-stage medical device innovation in a university setting deal with FDA compliance issues and the implications of this engagement for innovation. I conducted an exploratory case study of ten medical product development projects at the Rochester Institute of Technology (RIT). Overall, I found …

Exposure To Pesticides And Hepatocellular Carcinoma (Hcc) Risk In And Around Monroe County, Ny, Theodros Woldeyohannes

Theses

The impact of long-term exposure and persistence of pesticides in the environment on human biology is not completely understood. With the proliferation of pesticide application technologies, there have been documented associations between exposure to every major functional group of pesticide and adverse health effects in humans such as cancer and neurological disease. Of observed pesticide-induced cancer health-risks, hepatocellular carcinoma (HCC) has shown some of the most significant associations. Epidemiological study is complex, especially when examining pesticide health risks. It is difficult to understand the significance behind interactions between the large list of pesticide compounds, external environmental factors, and biological variables. …

Functional Investigations Of Proteins And Enzymatic Toxins From Full-Length-Enriched Cdna Of Timber Rattlesnake (Crotalus Horridus), Joshua Osula

Theses

Snake Venom is a highly modified form of saliva, contains hundreds of zootoxins, necrotoxins, cytotoxins, neurotoxins, and mytotoxins, all of which are primarily made up of mostly proteins, polypeptides, and other components such as enzymes, lipids, and carbohydrates. Although snake venom is known for its harmful effects, it has also had a positive impact in scientific discovery and medicine. Some toxins from snakes function to inhibit pain, and this means they can be very effective analgesics. For instance, crotalphine is considered a 14-amino-acid-peptide that has a disulfide bond and shows analgesic properties through TRPA1 desensitization. This …

Effects Of Eye Imagery On Criminal Justice And Forensic Students Cheating In Online Testing, Kortni Larue

Theses

Crime Prevention Through Environmental Design (CPTED) is a well-established subsection of environmental criminology in which aspects of the environment are altered in order to prevent crimes before they happen. This is primarily accomplished in two ways: physical and psychological. CPTED strategies often utilize both in order to prevent crime, but there is a lack of primarily psychologically based research in circulation. This includes the manipulation of the biopsychological response to gaze detection in order to increase prosocial behavior. Additionally, there is a lack of studies indicating if CPTED strategies are effective in a classroom setting and even less concerning online …

Algal Wrack Community Composition And Succession On A Sandy Beach In San Diego, Ca, Marisol Palomares

Theses

Sandy beaches are high-energy impact zones that produce little to no organic material. Much of the organic matter on beaches is washed up on shore in the form of algal wrack, providing a vital source of nutrients, food, and habitat for a variety of organisms on the sandy beach. Over time wrack will decay and decompose, releasing nutrients including nitrogen and phosphorus, which are consumed by benthic microalgae and bacteria. The type of wrack and geomorphology of the beach environments affect decomposition, which in turn supports a variety of different wrack associated macrofaunal communities. Different species of algal wrack will …

Electrical Identification Of Innate Immune Cells, Rasha Ayman Nasser

Theses

This thesis is concerned with the electrical characterization of the key players of the innate immune cells. Innate immunity is basically the nonspecific immune response that is triggered by any foreign body that attacks the human system. The key players of the innate immune system are mainly dendritic cells and macrophages. Accurately classifying these cell types helps us understand the mechanism of the immune system thereby enabling the development of models to improve new prospects for therapeutics and diagnostics. The characterization described in this thesis is based on extracting the capacitance for each biological cell using I-V curves. The main …

Nature-Inspired Topology Optimization Of Recurrent Neural Networks, Abdelrahman A. Elsaid

Theses

Hand-crafting effective and efficient structures for recurrent neural networks (RNNs) is a difficult, expensive, and time-consuming process. To address this challenge, this work presents three nature-inspired (NI) algorithms for neural architecture search (NAS), introducing the subfield of nature-inspired neural architecture search (NI-NAS). These algorithms, based on ant colony optimization (ACO), progress from memory cell structure optimization, to bounded discrete-space architecture optimization, and finally to unbounded continuous-space architecture optimization. These methods were applied to real-world data sets representing challenging engineering problems, such as data from a coal-fired power plant, wind-turbine power generators, and aircraft flight data recorder (FDR) data.

Initial work …

Exploring The Visual Arts With Rog: A Four-Part Series, Roger Heuberger

Theses

This project report addresses the research which led to the choice of content, formatting of curriculum, delivery system, and video conference management. The combined art appreciation and art history classes are innovative as they are built around high-interest key art events or movements instead of linear chronologies or systematic reviews of art elements. The research for this Thesis II project extended beyond art historical materials. The literature review and analysis additionally explored educational theories which could be adapted for use with the target audiences of 65+ aged seniors and lifelong learners. The original project submitted in mid-2019 was for in-class …

Evaluating Appearance Differences Of Color 3d Printed Objects, Matt Ronnenberg

Theses

Color 3D printing is a relatively young technology with several exciting applications and challenges yet to be explored. One of those challenges is the effect that three dimensional surface geometries have on appearance. The appearance of 3D objects is complex and can be affected by the interaction between several visual appearance parameters such as color, gloss and surface texture. Since traditional printing is only 2D, several of these challenges have either been solved or never needed to be addressed. Complicating matters further, different color 3D printing technologies and materials come with their own inherent material appearance properties, necessitating the study …

Application Of Machine Learning Models: Stock Price Forecasting Of The Philippines' Top Six Conglomerates, Anthony Rey Llanos

Theses

The advent of digital age dramatically changed the way all aspects of commerce is conducted. From the largest multi-national conglomerates to the least small-and-medium enterprises and to the unassuming business-savvy individuals have adapted to take advantage of the benefits afforded by the resulting digital technology. Investing in, and profiting from, shares of stocks of companies listed in an organized stock exchange is one such instance. Gone are the days wherein stock investors and brokers are inseparable from their telephones to handle trades. Online platforms, powered by machine learning algorithms, have made investing in stocks not only accessible and convenient but …

Fine-Tuning Sign Language Translation Systems Through Deep Reinforcement Learning, Joseph Panaro

Theses

Sign language is an important communication tool for a vast majority of deaf and hard-of-hearing (DHH) people. Data collected by the World Health organization states that there are 466 million people currently with hearing loss and that number could rise to 630 million by 2030 and over 930 million by 2050 \cite{DHH1}. Currently there are millions of sign language speakers around the world who utilize this skill on a daily basis. Bridging the gap between those who communicate solely with a spoken language and the DHH community is an ever-growing and omnipresent need. Unfortunately, in the field of natural language …

The Effect Of Deer Browse On Achyranthes Japonica, Nicholas R. Seaton

Theses

AN ABSTRACT OF THE THESIS OFNicholas Seaton, for the Master of Science degree in Plant Biology, presented on December 4, 2019 at Southern Illinois University Carbondale. TITLE: THE EFFECT OF DEER BROWSE ON ACHYRANTHES JAPONICAMAJOR PROFESSOR: Dr. David GibsonPlants respond in many ways to damage. These responses vary between sites depending on the severity and duration of the incident. One common form of damage in the forest understory is herbivory or browse. White tailed deer (Odocoileus virginianus) have been observed to change the dominant species of forests by selectively browsing palatable species in the understory. These changes in species dominance …

Differentiating Between Invasive And Native Populations Of Bighead And Silver Carp Using Ms-Aflp, Erika Renee Sarvela

Theses

When a species is introduced outside their native range, the genetic diversity of the introduced population is generally decreased due to the founder effect, and the fitness of individuals in the introduced population may decrease due to inbreeding depression. Invasive species are a paradox to this paradigm because while the initial population size of an invasive species may be small in their non-native range, the individuals are able to survive, eat, and reproduce so successfully, that they have deleterious effects on native species. One mechanism that invasive species use to overcome a lack of genetic diversity and adapt to their …

Identification Of Micrornas Related To Type 2 Diabetic Osteopath, Mouza Mohammed Saeed Alfashti Alaleeli

Theses

T2DM is linked to an increase in the fracture rate as compared to the non-diabetic population even with normal or raised Bone Mineral Density (BMD). Previous studies have addressed the question of how T2DM induces osteoporosis; the exact underlying mechanism is still elusive. Bones undergo continuous remodelling throughout life. Bone remodelling implicates the coupling of osteoclastic bone resorption and osteoblastic bone formation. This process is controlled by numerous genetic, hormonal, and neurogenic mechanisms. Osteoporosis is a result of bone loss that occurs by uncoupled remodelling. The existing evidence indicates that short non-coding RNAs known as microRNAs (miRNAs), are the key …

Trilepisium (Moraceae): Four New Species From Madagascar, Shawn Kelley

Theses

Trilepisium is a genus of tree with two member species: T. madagascariense and T. gymnandrum. This genus shows diversity in habit and morphology greatly exceeding that expected of a genus with two member species. Concerted collection efforts since the last revision have suggested there are several unrecognized species within Trilepisium and a revision is needed. Chapter one of this thesis details the history of this taxanomically challenging genus and presents the results of our study of 600 Malagasy herbarium specimens. Trilepisium is more adequately circumscribed as containing 17 species, 11 of which are new to science. Chapter two contains …

New Methods For Deep Learning Based Real-Valued Inter-Residue Distance Prediction, Jacob Barger

Theses

Background: Much of the recent success in protein structure prediction has been a result of accurate protein contact prediction--a binary classification problem. Dozens of methods, built from various types of machine learning and deep learning algorithms, have been published over the last two decades for predicting contacts. Recently, many groups, including Google DeepMind, have demonstrated that reformulating the problem as a multi-class classification problem is a more promising direction to pursue. As an alternative approach, we recently proposed real-valued distance predictions, formulating the problem as a regression problem. The nuances of protein 3D structures make this formulation appropriate, allowing predictions …

Design Of A Comprehensive Modeling, Characterization, Rupture Risk Assessment And Visualization Pipeline For Abdominal Aortic Aneurysms, Golnaz Jalalahmadi

Theses

Abdominal aortic aneurysms (AAA) is a dilation of the abdominal aorta, typically within the infra-renal segment of the vessel that cause an expansion of at least 1.5 times the normal vessel diameter. It is becoming a leading cause of death in the United States and around the world, and consequentially, in 2009, the Society for Vascular Surgery (SVS) practice guidelines expressed the critical need to further investigate the factors associated with the risk of AAA rupture, along with potential treatment methods. For decades, the maximum diameter (Dmax) was introduced as the main parameter used to assess AAA behavior and its …

Hyperspectral Properties Of Date Palm Trees (Phoenix Dactylifera L.), Mohamed Ali Saeed Ahmed Al Abdouli

Theses

The goal of this study is to classify the Date Palm varieties based on hyperspectral signature technology since it is difficult to identify the Date Palm cultivars without fruits. It will also help to obtain the hyperspectral signature for different types of date palm trees. Moreover, it also assists to determine the wavelength fingerprint of each cultivar and to recommend the best classification protocol differentiating among different cultivars based on spectral signature. Utilizing the Hyperspectral imaging technology precisely on the leaves of different Date Palm cultivars, thus facilitating identification of date palm cultivars without the fruits and make the spatial …

One-Pot O-Alkylation And C-C Cross-Coupling Reactions Involving Stabilized Phosphoranes, Areej Hashim Mohamed

Theses

This thesis is concerned with the one-pot reactions that are considered to be beneficial to preserve resources, save time, and are deemed a green chemistry strategy. To plan such one-pot reactions, it is important to combine two or more reactions that are compatible with each other and can be run under the same reaction conditions. In this work, possibilities of a combination of Wittig-olefination and Suzuki C-C-cross coupling reactions are explored further. Reaction sequences involve the combination of a Suzuki-reaction / Wittig olefination, a Suzuki reaction / Wittig olefination/hydrolysis, and a Suzuki-reaction / double Wittig olefination. In all cases, stabilized …