Digital Commons Network^™

Molecular Mechanisims Underlying The Anti-Cancer Activity Of Gum Arabic From Acacia Sp. In Triple-Negative Breast Cancer Cells, Sawsan Yaslam Hussein Alyafii

Theses

Metastatic breast cancer is the leading cause of cancer-related deaths among women worldwide. Triple-negative breast cancer (TNBC) is the most aggressive, accounting for 15-20% of all breast cancer cases. As TNBC cells lack the expression of hormone receptors estrogen receptors (ER) and progesterone receptors (PR) and human epidermal growth factor receptor 2 (HER2), TNBCs are unresponsive to hormonal therapy and often become highly resistant when exposed to standard chemotherapy, which has been identified as a major obstacle in TNBC treatment. Gum Arabic, a natural exudate produced from plants, is widely used traditionally for religious, cosmetics as well as medicinal purposes …

Molecular Mechanisims Underlying The Anti-Cancer Activity Of Gum Arabic From Acacia Sp. In Triple-Negative Breast Cancer Cells., Sawsan Yaslam Alyafii

Theses

Metastatic breast cancer is the leading cause of cancer-related deaths among women worldwide. Triple-negative breast cancer (TNBC) is the most aggressive, accounting for 15-20% of all breast cancer cases. As TNBC cells lack the expression of hormone receptors estrogen receptors (ER) and progesterone receptors (PR) and human epidermal growth factor receptor 2 (HER2), TNBCs are unresponsive to hormonal therapy and often become highly resistant when exposed to standard chemotherapy, which has been identifies as a major obstacle in TNBC treatment. Gum Arabic, a natural exudate produced from plants, is widely used traditionally for religious, cosmetics as well as medical purposes …

A Reinforcement Learning Approach To Vehicle Path Optimization In Urban Environments, Shamsa Abdulla Al Hassani

Theses

Road traffic management in metropolitan cities and urban areas, in general, is an important component of Intelligent Transportation Systems (ITS). With the increasing number of world population and vehicles, a dramatic increase in road traffic is expected to put pressure on the transportation infrastructure. Therefore, there is a pressing need to devise new ways to optimize the traffic flow in order to accommodate the growing needs of transportation systems. This work proposes to use an Artificial Intelligent (AI) method based on reinforcement learning techniques for computing near-optimal vehicle itineraries applied to Vehicular Ad-hoc Networks (VANETs). These itineraries are optimized based …

The Role Of School Principals In Fostering The Teamwork Success In Al Ain Schools From Teachers’ Percpective, Afra Mohammed Al Shamsi

Theses

The aim of the present study is to investigate the role of principals in fostering teamwork success. This study explained the leadership practices in fostering teamwork as perceived by teachers. Notably, the teamwork and its importance are neglected most of the time. Additionally, very little work was found in context of UAE. A sample of 334 public school teachers from Al Ain completed the online survey about their satisfaction about teamwork rates, their views regarding principals fostering teamwork, as well as recommendations and suggestions that could promote teamwork among school teachers. Descriptive statistics is adopted to analyze the quantitative items …

Assimilating Requirements Specification For Space Manned Missions: A Novel Approach, Khalfan Mohamed Al Remeithi

Theses

Aligned with the UAE Space Strategy 2117, which aims to establish the first inhabitable human on the Martian Surface by 2117, and with the current enthuse toward space tourism, the thesis proposes a novel framework to assimilate the process of requirement specification for a Manned Mission to Mars surface. Deep Space manned missions are unique and characterized by a set of specific requirements that should be elicited from different sources and stakeholders to ensure the missions’ success. In addition, these missions are highly dependent on the software components in the Command and Data Handling System (CDHS), which is used to …

The Effects Of Design Parameters On The Neural Recordings With Micro-Ecog Arrays, Manan Amish Sethia

Theses

In the field of neural prosthetics, electro-cortico-graph (ECoG) arrays are commonly used to record neural activity of the brain cortex both in animal and human subjects. A finite element model (FEM) was developed to simulate the electric field generated by a single neuron in the rat brain cortex and a micro ECoG array (µECoG) placed on the pia surface for recording the neural signal. The neuron was simulated as a dipole current source with a magnitude of 1µA and placed at three different depths in the motor cortex corresponding to different layers under the µECoG array. The array design was …

Short Term Temperature Forecasting Using Lstms, And Cnn, Darshan Shah

Theses

Weather forecasting is a vital application in present times. We can use the predictions to minimize the weather related loss. Use of machine learning and deep learning algorithms for forecasting, can eliminate or reduce the necessity of big data and high computation dependent process of parameterization. Long Short-Term Memory (LSTM) is a widely used deep learning architecture for time series forecasting. In this paper, we aim to predict one day ahead average temperature using a 2-layer neural network consisting of one layer of LSTM and one layer of 1D convolution. The input is pre-processed using a smoothing technique and output …

Finite Element Modeling Of Underwater Acoustic Environments And Domain Decomposition Methods, General Ozochiawaeze

Theses

Underwater acoustic scattering problems have several important applications ranging from sonar imaging in target detection to providing information for sediment classification and geoacoustic inversion. This work presents numerical methods for time-harmonic acoustic scattering problems, specifically, finite element methods for the Helmholtz equation. Furthermore, an iterative domain decomposition formulation is introduced for acoustic scattering problems where the physical domain consists of multiple layers of different materials.

The Role Of Irak-1 Transcripts In Sepsis, Adithya Subramanian Sahasranamam

Theses

Sepsis is a complex, life-threatening syndrome that can lead to systemic organ failure and dysfunction. Its high morbidity and mortality rates makes it a critical global health issue. The primary factors at play during sepsis are abnormal inflammation and a lack of oxygen supply to the tissues and muscles. The toll-like receptors play a crucial role in eliciting innate immune in response to infection, primarily through the interleukin-1 receptor-associated kinase (IRAK) pathways. Disturbances in the homeostasis of IRAK signaling cascades can lead to immune dysfunction. n this paper, we review the molecular mechanisms of IRAK-1, an important mediator of TLR-induced …

Assembly And Detection Of 3-D Qr Codes Through Additive Manufacturing And Terahertz Imaging, Patrick Dunn

Theses

Automatic identification and data capture, or AIDC, plays a substantial role in contemporary business, advertising, and military needs. The purpose of this study is to generate a potential alternative to current AIDC approaches by constructing three-dimensional plastic tags (or ‘3D QR codes’) using additive manufacturing techniques and interrogate them using Terahertz radiation. 3D Quick Response (QR) codes are designed in 3D computer-aided design software. The QR codes are 3D structures embedded in the printed plastic in which an air gap in the plastic (or an air gap filled in with another type of plastic) indicates a bit of information. Information …

Land Cover Image Segmentation Based On Individual Class Binary Segmentation, Sathyanarayanan Somasunder

Theses

Remote sensing techniques have been developed over the past decades to acquire data without being in contact of the target object or data source. Their application on land-cover image segmentation has attracted significant attention in recent years. With the help of satellites, scientists and researchers can collect and store high resolution image data that can be further processed, segmented, and classified. However, these research results have not yet been synthesized to provide coherent guidance on the effect of variant land-cover segmentation processes. In this paper, we present a novel model that augments segmentation using smaller networks to segment individual classes. …

Optimization Of Standard Buildings, Ahmed Alkaabi, Saleh Albreiki, Sultan Alawadhi, Yahya Alzarooni

Theses

Different utility sectors in the GCC prefer to adhere to a strict structural structure in order to make their offerings more efficient and satisfy specific customer needs. These layouts often include at least a few facilities, including the facility's security office, fire pump system and operation specifications, and the main facility support house. The challenges in designing these facility structural layouts appear to result in enormous expense requirements, which will be discussed in this article. Multiple buildings on a single plot result in multiple distinct "rafts," each with its own set of access conditions. Getting multiple foundations/buildings, on the other …

Limitations Of Artificial Intelligence, Sahar Sultan

Theses

Artificial Intelligence is a groundbreaking technology that is now an established field. It is being used to mimic human capabilities such as speaking, listening, learning, and planning by using different algorithms to process data and produce results depending on the information provided by the user. Artificial Intelligence has been used in several industries when it comes to data processing and decision making. Artificial Intelligence has been invented to help decision and solutionmaking processes using a problem-solving approach. The development of Artificial Intelligence software provides efficiency and acceleration on different kinds of workflows, which will help organizations increase their profit and …

Centering Black Trans Lives: Social Network Exploration Of #Blacktranslivesmatter Content On Twitter, Jordan Brooks

Theses

May 27, 2020 saw the fatal shooting of Tony McDade, a Black transgender man. McDade is one of many lives underlying the Black Lives Matter movement which, in 2020, became the largest movement in United States’ history. Although the Black Lives Matter movement has successfully brought the reality of systemic racism in the United States to the forefront of media, there remains a lack of visibility for and conversation surrounding the most vulnerable members: the Black transgender community. Through an intersectional lens, this thesis broadly examines the sentiment surrounding tweets utilizing the #blacktranslivesmatter hashtag, and how the intersection of race …

Leading A Horse To Water: Investigating The Semiotic Motif Of Water And Drowning In Bojack Horseman, Zachery A. Sherman

Theses

This semiotic analysis examines the affect that trauma, in the form of metaphor or semiotic motif involving water, has on the titular character of BoJack Horseman in Netflix’s BoJack Horseman (2014-2020) as well as how the use of water mirrors generational trauma passed down via historical associations. The impact that this trauma has upon these characters is frequently paired with water imagery and symbolism. The show’s use of water draws particular attention to how its characters perpetuate aspects of their traumatic pasts in their day-to-day life and reveals the nuanced psychological impact inherent to trauma while simultaneously hinting at its …

Social Media Influencer Motivation: Exploring What Drives Micro-Celebrities To Produce Content Using Social Exchange Theory, Jennie Giardino

Theses

Social media influencers are online celebrities who have the power to shape the opinions of audience members due to their relatable qualities. Influencer sponsorships have changed the nature of social media platforms and the strategy by which the content is posted. But besides the potential to be sponsored, why do influencers post content? The purpose of this study was to understand what motivates influencers to post content through the lens of social exchange theory by identifying resources exchanged between the social media influencer and the audience and explain how this affects their motivation to post content. I interviewed 15 lifestyle …

Cost Saving Proposal For Dubai Main Wastewater Pumping Stations, Mohammad Mansoor, Khaled Alhosani

Theses

A city that is free of hazardous chemical and pollution is a city with safe and healthy population. Keeping a city such as Dubai safe and healthy is a never ending task with too many stakeholders and too many variables. Examples are reducing carbon footprint, timely trash disposal, wastewater management, and the list goes on. Wastewater management is one of the most important and essential requirement for keeping the city and its people safe and healthy. There is an existing sewerage system that the emirate of Dubai continues to heavily rely on. The network includes the pipelines, the wastewater pump …

Unforeseen Connections, Miranda Mattson

Theses

Using floriography within my own work, I captured the essence of human emotion and used its familiarity to bring mental health issues to the foreground of conversation. The parallels of hidden emotion and social discordance between the Victorian era and the 21st Century inspired my introspective research into "invisible" illnesses: health issues that affect both the mind and the body, respectively. Utilizing knowledge in mixed media, as well as traditional metalsmithing techniques, these ideas manifested into a series of wearable art and sculpture with the intention of prompting in-depth discussions on mental health stigmas. Without compromising the ambiguity of floriography, …

Intelligent Statcom Voltage Regulation Using Fuzzy Logic Control, Saleh Hussein

Theses

Reactive power compensation is a very important and challenging task in electrical power systems today. Future trends foreseen in power systems such as high interconnectivity and the integration of renewable energy resources produce even more issues related to power system control and stability. Flexible AC transmission systems are vastly used in power systems in order to mitigate several performance aspects found in typical power systems. One shunt connected device in particular, STATCOM, is very powerful and commonly used in voltage regulation at the power transmission level. STATCOM uses voltage sourced converters to inject or absorb reactive power from the power …

If It Ain’T Here When I Get Back, Clara Riedlinger

Theses

If It Ain’t Here When I Get Back is a short film which explores themes of sibling rivalry, time and memory, our relationship to place, and the porous line between childhood and adulthood. It was produced between March 2020-April 2021 including pre-production to post-production. This paper describes and analyzes the filmmaking process for Clara Riedlinger, director. In this paper I will also attempt to put to words the intangibles of that process, including the social dynamics of filmmaking, and larger cultural happenings at the time of production.

Exploring The Impact Of Legalization Of Recreational Marijuana On Adolescent Drug Use, Camila Camps

Theses

This paper provides an overview of the history of America’s war against drugs and the impact that this figurative war has had on American society. It is clear that the war on drugs has disproportionately harmed racial/ethnic minorities. Punitive policies currently in place have diverted resources away from the social and economic growth of these communities. This is why there is a movement towards working to reform drug laws in order to address the country's drug crisis. The final section includes recommendations that can improve our current response against marijuana.

Beneath The Bandage: The Impact Of Violence On Individuals And Communities, Jessica Burt

Theses

Violence is an issue nationally and locally within the City of Rochester. It is one of the most complex issues that society faces and attempts to resolve. However, despite many efforts to combat violence, it persists. Research shows that since the early 2000’s, there have been fluctuations in the number of homicides and shootings in Rochester, but long-term analyses on the level of violence show that it has remained relatively stable over time (Altheimer et al., 2017). Although stable, there is a concentration of violence and many individuals, communities, and institutions are affected by it. This paper will discuss violence …

A Mobile App That Helps Asthmatic Patients Monitor Air Quality In Real Time, Jiani Su

Theses

Asthma is a chronic disease that cannot be cured. Every attack of asthma is a physical and mental destruction to patients, bringing pain and economic burden to patients, and seriously affecting the quality of life and happiness index of patients. But the vast majority of asthma cases can be completely controlled with appropriate treatment and intervention. Investigations at home and abroad have found that the self-health management level of asthma patients is still at a relatively low level, and more than half of asthma patients are in a state of out-of-control.

Currently, there is no online software that can effectively …

Basic Police Officer Training In The U.S., Bryan Cammerino

Theses

Policing in America has grown to become a topic of paramount interest within society today. This interest has included increased attention to the role that the police play within local communities. Gaining a greater understanding of where policing started, how it has evolved, and where it is today can help us better understand the importance of police officer training. Focusing on Americas policing eras and various policing models will establish a precedent to explain why policing is the way it is today. This paper will then be able to pinpoint various current events that make the history of policing come …

Assembly And Annotation Of The Genome Of An Invasive Bush Honeysuckle, Amur Honeysuckle (Lonicera Maackii), Erin R. Kesel

Theses

Invasive species are a global problem that cause significant environmental and economic damage. It has been estimated that the cost of invasive species in the United States is at least 120 billion dollars annually. Lonicera maackii, commonly known as Amur honeysuckle, is an invasive shrub found in New York State. In invaded regions, L. maackii has caused decreased species richness of native plant and animal species. It has also negatively affected the native migratory bird populations that eat the plant’s berries. Currently, there is no available genomic sequence for any Lonicera species. With next generation sequencing, new information can be …

Facilitating Serendipitous Communication, Interaction And Collaborative Flow In Mixed Realities While Working Remote., George Deacon Theodore Harvey

Theses

Working remotely can often lead to fatigue and stress which in turn reduces productivity. The author will explore the concept that with proper communication, environments that promote serendipitous meeting and effective collaboration, can result in happier workers. The author will also explore how speculative design can improve remote work and provide vision for future work scenarios. This concept will focus on the development of interaction design for use with mixed realities, 3D capture systems and mid-air haptic technology to create a seamless and engaging remote working environment.

This paper will show how work culture and communication can affect mental health …

Port-All: Reproduction Of The Sense Of Companionship In A Long-Distance Relationship, Xincan Yang

Theses

The long-distance relationship is a common phenomenon in contemporary society. Nowadays with the development of the Internet, we have various instant messaging software which gives us an effective way to keep communication with distant others. But it also brings a series of new problems.

Due to the lack of physical contact, time difference, and high dependence on the Internet, people often experience negative emotions in long-distance relationships from delayed communication, suspicion, and misunderstanding of messages. Research shows that most couples feel tired and anxious for a long time in a long-distance relationship, and one of the core reasons is the …

Esports Game Skill Analysis & Prediction: League Of Legends, Abedalaziz Zandaki

Theses

Esports has been an explosive business especially with the current pandemic situation, it is rising to unparalleled levels of popularity as everything is going digital, Riot Games’ League of legends, which is considered one the most played video games right now with 27+ Million players per day and 115 Million over a month, checks many boxes where value can be obtained.[12] The general idea is that the game has a ranked ladder system, where players are evaluated by their win to lose ratio which is influenced by their skills in-game, each individual game performance counts towards the win or lose …

A Comprehensive Feasibility Study For A Wooden Plastic Composite Project, Rami Kamal Ibrahim Elgharouri

Theses

Millions of tons of wastage are produced every year ending up in landfills or burn and causing an environmental problem as they threaten the health of creatures and cause resources depletion. 44% of wastage is organic waste, which is biodegradable. However, 17% and 12% of wastage are paper and plastic respectively, and both are non-degradable. Thus, the comprehensive solution is to recycle them. A suggested solution is to recycle them into wood plastic composite. Up to 90% of WPC raw material is a recycled material, and the final product is 100% recyclable. WPC is comparatively less energy-consuming than other substitute …

The Racked System: A Historically Based Interactive Roleplaying Experience, Will Truran

Theses

“History repeats itself” is a saying we are all too familiar with, but why is that true? As we look at our modern society we can see that pain persists and hate crimes are on the rise, particularly those of antisemitism and those holding anti-Asian ideologies. The Racked System aims to address this by introducing a new method of learning about our past so that we can apply its lessons to our future. Classroom settings require students to memorize dates and data that often capture hard to comprehend facts, like that six million Jews were murdered in the Holocaust. It …