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Point Prevalence Of Type B Tympanogram In Children, Siraj M. Zakzouk, Khariya A. Abduljawad Jun 2002

Point Prevalence Of Type B Tympanogram In Children, Siraj M. Zakzouk, Khariya A. Abduljawad

Saudi Medical Journal

OBJECTIVE: Otitis media with effusion is a common disease; it is primarily a disease of children. Otitis media with effusion was found as the most common cause of hearing impairment among children. The prevalence varied in different populations. Using otoscopy and tympanometry usually gives a valuable indication of the presence of otitis media with effusion. The aim of this study is to determine the point prevalence of type B tympanogram as a diagnostic and indication of the presence of otitis media with effusion. METHODS: This study was carried out during the period September 1997 through to May 2000. The study …


An Audit Of Oxygen Therapy On The Medical Ward In 2 Different Hospitals In Central Saudi Arabia, Abdullah F. Al-Mobeireek, Abdullah A. Abba Jun 2002

An Audit Of Oxygen Therapy On The Medical Ward In 2 Different Hospitals In Central Saudi Arabia, Abdullah F. Al-Mobeireek, Abdullah A. Abba

Saudi Medical Journal

OBJECTIVE: To study the use of oxygen therapy on the medical wards in 2 hospitals in Riyadh, Kingdom of Saudi Arabia. One was academic, King Khalid University Hospital and the other a community hospital, Riyadh Medical Complex. METHODS: This study was carried out over a one year period, 6 April 2000 through to 6 April 2001. Oxygen saturation was measured randomly by pulse oximetry in patients receiving oxygen therapy. Charts of the patients were inspected for relevant information related to oxygen therapy, including indications, dose, monitoring and documentation of the order. If oxygen saturation was >97% oxygen flow was reduced …


Prevalence Of Mental Illness Among Saudi Adult Primary-Care Patients In Central Saudi Arabia, Abdallah D. Al-Khathami, Danny O. Ogbeide Jun 2002

Prevalence Of Mental Illness Among Saudi Adult Primary-Care Patients In Central Saudi Arabia, Abdallah D. Al-Khathami, Danny O. Ogbeide

Saudi Medical Journal

OBJECTIVE: To determine the prevalence of mental illness morbidity among Saudi adult primary care patients from Al-Kharj, Kingdom of Saudi Arabia. METHODS: This is a cross-sectional epidemiological study of the prevalence of mental illness morbidity in a randomly selected sample of 609 Saudi adult patients, aged from 15 years to 65 years who attended Family and Community Medicine Clinic, Armed Forces Hospital, Al-Kharj, Kingdom of Saudi Arabia, from July 2000 to November 2000. The Rahim Anxiety-Depression Scale was used in the evaluation. RESULTS: In this study, 609 Saudi patients were screened. Their mean age ± standard deviation was 33.72 ± …


Acute Pancreatitis Complicated By Spontaneous Unilateral Adrenal Hemorrhage, Abdulsalam S. Ibrahim, Ali H. Latif Jun 2002

Acute Pancreatitis Complicated By Spontaneous Unilateral Adrenal Hemorrhage, Abdulsalam S. Ibrahim, Ali H. Latif

Saudi Medical Journal

A 52-year-old lady with a history of hypertension, dilated cardiomyopathy and diabetes mellitus type 2, presented with severe upper abdominal pain and vomiting of 4 hours duration. Acute pancreatitis was diagnosed based on high serum amylase and an abdominal computerized tomography scan. On the 3rd day she developed fever, increasing abdominal pain and shortness of breath. A repeated computerized tomography scan showed severe pancreatic necrosis and right adrenal hemorrhage.


Malignant Familial Long Qt Syndrome, Raghavan Subramanyan, Poothirikovil Venugopalan Jun 2002

Malignant Familial Long Qt Syndrome, Raghavan Subramanyan, Poothirikovil Venugopalan

Saudi Medical Journal

We report a family with congenital long QT syndrome, an inherited disorder of myocardial repolarization in which affected individuals have prolongation of corrected QT interval on the electrocardiogram and a tendency to develop ventricular arrhythmia, leading to syncope, convulsion or sudden death. Our family is characterized by several affected members (11/16), early onset of symptoms, malignant course prior to diagnosis and good response to beta-blocker therapy. The genetic basis of long QT syndrome has been traced to defective proteins encoding cardiac ion channels. Diagnosis is based on an unexplained prolongation of QT interval >0.45 second in the presence of suggestive …


Membranoproliferative Glomerulonephritis Due To Hepatitis C In Renal Allograft, Ahmed S. Al-Arrayed, Sara M. George, Kamaraju S. Ratnakar Jun 2002

Membranoproliferative Glomerulonephritis Due To Hepatitis C In Renal Allograft, Ahmed S. Al-Arrayed, Sara M. George, Kamaraju S. Ratnakar

Saudi Medical Journal

Membranoproliferative glomerulonephritis type 1 is an etiologically divergent disorder. Hepatitis C with or without cryoglobulinemia is considered one of the principal causes of de novo and post transplant membranoproliferative glomerulonephritis type 1. A 49-year-old male who underwent renal allograft for end stage renal disease developed proteinuria and positive hepatitis C serology during the post-transplant period. This was associated with moderate hepatic dysfunction, which necessitated both liver and renal biopsies. Features of both chronic active hepatitis and membranoproliferative glomerulonephritis type 1 were seen as a result of histological examination of both liver and renal biopsies. Ultra structural studies showing mesangial and …


Presacral Fibroma In A Young Laborer Presenting With Chronic Lumbago, Ahmed O. El-Nazeer, Mohamed E. Ahmed Jun 2002

Presacral Fibroma In A Young Laborer Presenting With Chronic Lumbago, Ahmed O. El-Nazeer, Mohamed E. Ahmed

Saudi Medical Journal

A 24-year-old patient had a long history of low backache. After examination he was found to have a presacral mass grossly displacing the rectum anteriorly. Surgical exploration revealed a large rounded mass (20x17x10cm) occupying the presacral space and adherent to the sacral promontory. The mass was totally excised. The histology was a benign fibroma. The patient persued an excellent post-operative course and has remained symptom free for one year now.


Researcher's Guide To Health Statistics, Ibrahim Mansoor Jun 2002

Researcher's Guide To Health Statistics, Ibrahim Mansoor

Saudi Medical Journal

No abstract provided.


Cecal Vascule. An Overlooked Mechanism Of Cecal Volvulus, Abdulmajeed Al-Abdulkareem, Alaa Abdul Jabbar Jun 2002

Cecal Vascule. An Overlooked Mechanism Of Cecal Volvulus, Abdulmajeed Al-Abdulkareem, Alaa Abdul Jabbar

Saudi Medical Journal

No abstract provided.


Ethical Considerations In The Prevention And Management Of Genetic Disorders With Special Emphasis On Religious Considerations, Mohammed A. Albar Jun 2002

Ethical Considerations In The Prevention And Management Of Genetic Disorders With Special Emphasis On Religious Considerations, Mohammed A. Albar

Saudi Medical Journal

Genetic diseases include not only single gene disoders, but multifactorial, somatic cell genetic disorders, mitochondrial and even chromosomal. One in 4 adults will suffer from a multifactorial or a somatic cell genetic disease. The common diseases in the community have a hereditary component namely diabetes mellitus, hypertension, ischemic heart diseases and many types of cancer. Even monogenic diseases which affect a small number of the newborns (2%-3%), have a greater impact on childhood diseases up to age 15 years. Therefore, it is imperative to scrutinize the available methods of prevention and management of genetic disorders, their ethical implications, and since …


Pediatric Living-Related Liver Transplantation In Saudi Arabia, Afef F. Bassas, Mona S. Al-Shahed, Hans G. Djurberg, Haider A. Al-Shurafa, Muaffak T. Jawdat, Hussa F. Al-Hussaini, Mehrun A. Zuleika, Hamoud A. Al-Hebby, Sami H. Wali Jun 2002

Pediatric Living-Related Liver Transplantation In Saudi Arabia, Afef F. Bassas, Mona S. Al-Shahed, Hans G. Djurberg, Haider A. Al-Shurafa, Muaffak T. Jawdat, Hussa F. Al-Hussaini, Mehrun A. Zuleika, Hamoud A. Al-Hebby, Sami H. Wali

Saudi Medical Journal

OBJECTIVE: The purpose of this paper is to report our experience of the first 29 consecutive living-related liver transplants in pediatric recipients and to demonstrate the feasibility of living-related liver transplantation in the Arab World. The first living-related liver transplantation in the Kingdom of Saudi Arabia was performed in November 1998 by Bassas et al following an appropriate period of multi-disciplinary preparation. METHODS: This study was carried out at the Armed Forces Hospital, Riyadh, Kingdom of Saudi Arabia, during the period November 1998 through to October 2001. A review of the data of the transplanted children and adult donors was …


The Effect Of Metformin Plus Clomiphene Citrate On Ovulation And Pregnancy Rates In Clomiphene-Resistant Women With Polycystic Ovary Syndrome, Hasan Y. Malkawi, Hussein S. Qublan Jun 2002

The Effect Of Metformin Plus Clomiphene Citrate On Ovulation And Pregnancy Rates In Clomiphene-Resistant Women With Polycystic Ovary Syndrome, Hasan Y. Malkawi, Hussein S. Qublan

Saudi Medical Journal

OBJECTIVE: To study the effect of metformin in combination with clomiphene citrate, as compared with placebo plus clomiphene citrate, on the ovulation and pregnancy rates in clomiphene citrate-resistant women with polycystic ovary syndrome. METHODS: This study was carried out at King Hussein Medical Center, Amman, Jordan, during the period January 2001 through to July 2001. Twenty-eight clomiphene citrate-resistant polycystic ovary syndrome women were evaluated prospectively for 6 treatment cycles by receiving metformin, 850mg twice daily throughout the cycle along with 50 mg clomiphene citrate, starting on day 5-9 of the same cycle (N=16), or by taking placebo with clomiphene citrate …


Etiology Of Chronic Diarrhea, Sabeha M. Al-Bayatti Jun 2002

Etiology Of Chronic Diarrhea, Sabeha M. Al-Bayatti

Saudi Medical Journal

OBJECTIVE: The aim is to find the common causes of chronic diarrhea in our hospital, and to find out the most useful methods for diagnosis. METHODS: This study was carried out in the medical ward at Al-Yarmouk Teaching Hospital, Baghdad, Iraq, during the period January 1999 through to August 2000. Fifty inpatients with diarrhea for 4 weeks or more were evaluated by history, physical examination and investigations which included endoscopy with biopsy. RESULTS: The first cause of chronic diarrhea was ulcerative colitis (28%), the next was celiac disease (20%), followed equally by microscopical colitis (12%) and functional diarrhea (12%), amebiasis …


Sero-Response To Measles-Mumps-Rubella Vaccine Campaign In Saudi Arabia, Yagob Y. Al-Mazrou, Mohamed K. Khalil, Salah Tumsah, Yasser S. Al-Ghamdi, Mohamed H. Al-Jeffri, Andore B. Tischer, Ameen A. Mishkhas, Mostafa Eissa Jun 2002

Sero-Response To Measles-Mumps-Rubella Vaccine Campaign In Saudi Arabia, Yagob Y. Al-Mazrou, Mohamed K. Khalil, Salah Tumsah, Yasser S. Al-Ghamdi, Mohamed H. Al-Jeffri, Andore B. Tischer, Ameen A. Mishkhas, Mostafa Eissa

Saudi Medical Journal

OBJECTIVE: To evaluate the measles-mumps-rubella vaccine campaign targeting primary school children in the Kingdom of Saudi Arabia during the months of January and February 2000. METHODS: Pre and post measles-mumps-rubella vaccine blood samples were collected from 54 children from the first grade and 96 children from the 6th grade. Antibodies against measles, mumps and rubella were assayed using enzyme immunoassay and a backup test of plaque neutralization test. This assay was carried out at the Reference Center, Koch Institute, Berlin, Germany. RESULTS: When the backup test results were added, 96%-98% of children had protection level against measles before the campaign. …


Malaria Parasitemia During Delivery, Sayed M. Ahmed, Ahmed A. Mohamedani, Ali B. Habour, Ali A. Sadek Jun 2002

Malaria Parasitemia During Delivery, Sayed M. Ahmed, Ahmed A. Mohamedani, Ali B. Habour, Ali A. Sadek

Saudi Medical Journal

OBJECTIVE: The aim of this study is to investigate the impact of plasmodium falciparum infection in parturient women in Central Sudan where malaria transmission is mesoendemic. The purpose of this paper is to find out the prevalence of malaria parasitemia and the risk of anemia among parturient women and to suggest appropriate strategies to lower their prevalence rates. METHODS: This prospective study was conducted at Medani Teaching Hospital, Sudan, a tertiary regional referral center, during the period January 1997 through to December 1997. All cases were admitted during labor to the delivery room and were clinically suspected to have malaria. …


Surgically Treated Transitional Cell Carcinomas Of The Bladder. The Role Of Radical Surgery, Muneer A. Al-Ali, Dawoud M. Kashmoula, Loay F. Haddad Jun 2002

Surgically Treated Transitional Cell Carcinomas Of The Bladder. The Role Of Radical Surgery, Muneer A. Al-Ali, Dawoud M. Kashmoula, Loay F. Haddad

Saudi Medical Journal

OBJECTIVE: To assess the treatment outcome and differentiate between the individual behavior of the tumor stages that were studied (Ta, T1, and T2a) with special reference to T2a tumors. METHODS: This study was carried out at Al-Rasheed Military Hospital, Baghdad, Iraq, during a 12 year period. Fifty-six patients with Ta, T1, and T2a (superficial invasion of muscularis propria) transitional cell carcinomas of the bladder, have been retrospectively analyzed. They were treated surgically with either transurethral of the bladder tumor (N=45) or radical surgery (N=11). Tumors with frequent recurrences or mulifocal or extending to the ureter or vesical outlet were treated …


Brca1 And Brca2 Mutations In Breast Cancer Patients From Saudi Arabia, El-Harith A. El-Harith, Maha S. Abdel-Hadi, Diana Steinmann, Thilo Dork Jun 2002

Brca1 And Brca2 Mutations In Breast Cancer Patients From Saudi Arabia, El-Harith A. El-Harith, Maha S. Abdel-Hadi, Diana Steinmann, Thilo Dork

Saudi Medical Journal

OBJECTIVE: The aim of this pilot study was to screen the major segments of the BRCA1 and BRCA2 genes for disease-associated mutations in Arab and Asian women with breast cancer from the Kingdom of Saudi Arabia. METHODS: Deoxyribonucleic acid samples from 29 Arab women and 11 Asian women, with unilateral breast cancer were investigated for BRCA1 and BRCA2 mutations. For this purpose single strand conformation polymorphism and direct nucleotide sequencing techniques were employed. This study was carried out at King Fahad Hospital of the University, Al-Khobar, Kingdom of Saudi Arabia, during the time frame March 2000 through to August 2001. …


Do Antibiotics Decrease Post-Tonsillectomy Morbidity?, Sami A. Al-Kindy Jun 2002

Do Antibiotics Decrease Post-Tonsillectomy Morbidity?, Sami A. Al-Kindy

Saudi Medical Journal

OBJECTIVE: A tonsillectomy audit was carried out and compared with other studies, to emphasize the role of antibiotics. METHODS: This study was carried out at North West Armed Forces Hospital, Tabuk, Kingdom of Saudi Arabia, during the year January 1999 through to December 1999. This is a retrospective study of patients who had tonsillectomy with or with adenoidectomy, the topics audited included indication for surgery, grade of surgeon, method of surgery, length of hospital stay, complications and the use of postoperative antibiotics. RESULTS: A total of 185 patients underwent tonsillectomy with or without adenoidectomy. The patients age ranged between 2 …


Retroperitoneal Fibrosis. Demographic, Clinical And Pathological Findings, Kamal E. Bani-Hani, Ibrahim H. Bani-Hani, Hussein A. Al-Heiss, Hamza Z. Omari Jun 2002

Retroperitoneal Fibrosis. Demographic, Clinical And Pathological Findings, Kamal E. Bani-Hani, Ibrahim H. Bani-Hani, Hussein A. Al-Heiss, Hamza Z. Omari

Saudi Medical Journal

OBJECTIVE: To describe the clinical characteristics of patients with retroperitoneal fibrosis including the etiopathogenesis, clinical features, diagnostic criteria and effective treatment of the disease. METHODS: This study was carried out at Princess Basma Teaching Hospital, Irbid, Jordan, during the year 2001. Records of 15 patients with retroperitoneal fibrosis were retrospectively reviewed. Demographic, clinical and pathological criteria was evaluated and analyzed. RESULTS: From 1990 to 2000, there were 15 patients seen with retroperitoneal fibrosis (10 men and 5 women; the mean age was 55.8 years, ranging between 39 years to 75 years). Nine cases were idiopathic and 6 were secondary. Risk …


Iatrogenic Perforation Of The Esophagus, Husain A. Al-Khawahur, Ahmed H. Al-Salem Jun 2002

Iatrogenic Perforation Of The Esophagus, Husain A. Al-Khawahur, Ahmed H. Al-Salem

Saudi Medical Journal

Iatrogenic perforation of the esophagus occurs rarely, and is most frequently seen in preterm and low birth weight infants. This is a report of 2 cases of iatrogenic perforation of the esophagus, outlining aspects of diagnosis and management.


Controversial Aspects In The Management Of Perforated Appendicitis In Children, Tarik F. Siddiquie, Sayed Qaiseruddin, Praphakar Rao, Ahmed H. Al-Salem Jun 2002

Controversial Aspects In The Management Of Perforated Appendicitis In Children, Tarik F. Siddiquie, Sayed Qaiseruddin, Praphakar Rao, Ahmed H. Al-Salem

Saudi Medical Journal

No abstract provided.


A Survey Of The Reasons For Vasectomy Refusal In Couples Who Have Chosen Tubectomy As Their Contraceptive Method, Zahra Kamyabi Jun 2002

A Survey Of The Reasons For Vasectomy Refusal In Couples Who Have Chosen Tubectomy As Their Contraceptive Method, Zahra Kamyabi

Saudi Medical Journal

No abstract provided.


Use Of Antiplatelets And Lipid Lowering Therapy In Patients With Peripheral Vascular Disease, Abdulaziz S. Aldawood, Roman Jaeschke May 2002

Use Of Antiplatelets And Lipid Lowering Therapy In Patients With Peripheral Vascular Disease, Abdulaziz S. Aldawood, Roman Jaeschke

Saudi Medical Journal

OBJECTIVE: To investigate the use of antiplatelet and lipid lowering therapy among patients undergoing peripheral vascular surgery, and to compare their use with that reported among a similar population of patients in Canada. METHODS: Chart review of a cohort of 52 patients undergoing peripheral vascular surgery. The study was carried out at King Fahad National Guard Hospital, Kingdom of Saudi Arabia in May 2000. RESULTS: On discharge, less than 50% of the patients received any antiplatelet or antithrombotic medication. Only 13% of the patients received lipid-lowering therapy. Those findings parallel those of Canadian publications. CONCLUSION: Current literature supports the use …


Adult Lead Poisoning From A Herbal Medicine, Abdulsalam S. Ibrahim, Ali H. Latif May 2002

Adult Lead Poisoning From A Herbal Medicine, Abdulsalam S. Ibrahim, Ali H. Latif

Saudi Medical Journal

A 56-year-old Indian lady presented with one week history of abdominal pain, jaundice and chronic polyarthralgia. She had evidence of hemolytic anemia and hepatitis. Her blood lead level was high and a peripheral blood film showed dense basophilic stippling. It is believed that the lead toxicity was due to the use of Indian herbal medicine.


The Middle-East Connection Of Wolman Disease, Durjoy K. Shome, Emtethal Al-Jishi, John F. Greally, Neelam Malik, Hassan A. Zainaldeen, Nagalla S. Das May 2002

The Middle-East Connection Of Wolman Disease, Durjoy K. Shome, Emtethal Al-Jishi, John F. Greally, Neelam Malik, Hassan A. Zainaldeen, Nagalla S. Das

Saudi Medical Journal

The clinical, laboratory and cytological features of 2 Bahraini infants with Wolman9s disease are described. While one of the cases showed the classical diagnostic features, the other case exhibited a few atypical features such as lack of adrenal calcification and unusual morphology of vacuolated marrow macrophages. Literature review shows that this disorder may not be rare in this region.


The Effect Of Magneto-Treated Blood Autotransfusion On Central Hemodynamic Values And Cerebral Circulation In Patients With Essential Hypertension, Ilgar G. Alizade, Nigar T. Karayeva May 2002

The Effect Of Magneto-Treated Blood Autotransfusion On Central Hemodynamic Values And Cerebral Circulation In Patients With Essential Hypertension, Ilgar G. Alizade, Nigar T. Karayeva

Saudi Medical Journal

OBJECTIVE: The work was carried out to study the effect of magneto-treated blood autotransfusion on the values of central and cerebral hemodynamics in patients with essential hypertension. METHODS: Sixty-six patients with stage II essential hypertension aged 31-60 years who underwent magneto-treated blood autotransfusion were evaluated and treated, at the Cardiology Department, Hospital of Ministry of Internal Affairs of the Azerbaijan Republic, over a period of 8 years. The diagnosis was based on clinical examination and generally accepted criteria of essential hypertension stages proposed in 1978 by the World Health Organization. RESULTS: Sixty-six patients with stage II essential hypertension with stable …


Extrapulmonary Tuberculosis, Epidemiology And Patterns In Saudi Arabia, Abdulrahman A. Alrajhi, Ali M. Al-Barrak May 2002

Extrapulmonary Tuberculosis, Epidemiology And Patterns In Saudi Arabia, Abdulrahman A. Alrajhi, Ali M. Al-Barrak

Saudi Medical Journal

Annual incidence rates of extrapulmonary tuberculosis have been increasing over the last few years in the Kingdom of Saudi Arabia. True rates may even be higher due to incomplete reporting. Diagnosis of this condition requires high clinical suspicion, special diagnostic procedures, special staining, and culture media for acid fast bacilli. Delayed diagnosis results in increasing morbidity, mortality, and cost to the health care system. Particularly in areas of high endemicity of Mycobacterium tuberculosis, clinicians should be aware of the various forms of extrapulmonary tuberculosis. The available epidemiology and patterns of various forms of extrapulmonary tuberculosis in the Kingdom of Saudi …


The Status Of Cadaveric Organ Donation For Liver Transplantation In Saudi Arabia, Mohammed I. Al-Sebayel May 2002

The Status Of Cadaveric Organ Donation For Liver Transplantation In Saudi Arabia, Mohammed I. Al-Sebayel

Saudi Medical Journal

OBJECTIVE: Over the past 2 decades, liver transplantation has became the standard treatment of end stage liver disease. Organ shortage has been the main hindrance against the progress of liver transplantation in the Kingdom of Saudi Arabia. This paper reports the status of organ donation for liver transplantation in the Kingdom of Saudi Arabia and highlights the problems and the suggested solutions in relation to organ shortage. METHODS: All donors reported to the liver transplant program at the King Fahad National Guard Hospital, Riyadh, Kingdom of Saudi Arabia, from the Saudi Center of Organ Transplantation from January 1994 through to …


Trends In The Management Of Blunt Liver Trauma, Mohammed A. Al-Gari, Sherif R. Hussein May 2002

Trends In The Management Of Blunt Liver Trauma, Mohammed A. Al-Gari, Sherif R. Hussein

Saudi Medical Journal

OBJECTIVE: Blunt liver trauma management has changed over the last 2 decades to include non-operative management as one of the standard approaches, particularly to those with minor liver injury. We reviewed the experience at a non-trauma hospital to identify trends in methods of evaluation and management of blunt liver trauma and discuss its outcome. METHODS: Medical records of 21 patients who sustained blunt liver trauma between June 1992 and July 1999 were retrospectively reviewed at King Fahad Military Medical Complex, Dhahran, Kingdom of Saudi Arabia. RESULTS: Thirty-three percent received non-operative management and recovered without complications. The rest received an operative …


A Pilot Study Of Cardiac Troponin I In Patients With Acute Myocardial Infarction And Unstable Angina, Najlaa A. Selim, Houssem T. Hmouda May 2002

A Pilot Study Of Cardiac Troponin I In Patients With Acute Myocardial Infarction And Unstable Angina, Najlaa A. Selim, Houssem T. Hmouda

Saudi Medical Journal

OBJECTIVE: To assess the value of cardiac troponin I in the initial management of acute myocardial infarction and unstable angina, as well as the concordance between creatine phosphokinase-cardiac isoenzyme and cardiac troponin I. METHODS: We reviewed retrospectively the charts of 32 patients with acute myocardial infarction or unstable angina admitted to the Intensive Care Unit from the Emergency Room of King Khalid Military City Hospital, Hafar-Al-Batin, Kingdom of Saudi Arabia from April 1998 to September 2000. The time of admission to the intensive care unit, which corresponds to the beginning of thrombolytic therapy, the time when cardiac enzymes (creatine phosphokinase-cardiac …