Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Articles 721 - 750 of 7869

Full-Text Articles in Entire DC Network

Incidence, Risk Factors, And Maternal Outcomes Of Major Degree Placenta Previa: A 10-Year Retrospective Analysis, Mehad H. Alqasem, Ayman H. Shaamash, Ahmed A. Mahfouz, Mamdoh A. Eskandar Sep 2023

Incidence, Risk Factors, And Maternal Outcomes Of Major Degree Placenta Previa: A 10-Year Retrospective Analysis, Mehad H. Alqasem, Ayman H. Shaamash, Ahmed A. Mahfouz, Mamdoh A. Eskandar

Saudi Medical Journal

Objectives: To determine the incidence, risk factors, and maternal outcomes of “major degree” placenta previa (PP)/placenta accreta spectrum (PAS) in Abha Maternity and Children’s Hospital, Abha, Saudi Arabia. Secondly, to compare our findings to those of previous studies on PP/PAS in Saudi Arabia. Methods: This is a retrospective study that included 299 patients diagnosed with major degree PP/PAS and admitted to Abha Maternity and Children’s Hospital, Abha, Saudi Arabia, within 10 years (January 2012-December 2021). Also, we compared our results to the outcomes of PP/PAS patients in 6 previous Saudi studies. Results: The total number of deliveries was 54,341; PP …


Factors Predicting Medication Adherence Among Coronary Artery Disease Patients In Saudi Arabia: A Descriptive Study, Abdulaziz M. Almarwani, Bayan M. Almarwani Sep 2023

Factors Predicting Medication Adherence Among Coronary Artery Disease Patients In Saudi Arabia: A Descriptive Study, Abdulaziz M. Almarwani, Bayan M. Almarwani

Saudi Medical Journal

Objectives: To measure medication adherence among coronary artery disease (CAD) patients and identify sociodemographic factors that are medication adherence predictors. Methods: A cross-sectional correlation design was carried out, following the STROBE guidelines. The study was carried out in a specialized cardiac center in the western region of Saudi Arabia between March 2019 and January 2020. A total of 278 patients completed the study survey. Results: The majority of participants (59.4%) reported moderate medication adherence, and the remainder reported poor (30.6%) and good (10%) medication adherence. It was found that women patients, patients with higher education levels, non-smokers, patients who regularly …


Comparison Of The Effects Of Alpha Lipoic Acid And Dexpanthenol In An Experimental Tracheal Reconstruction Animal Model, Murat Kuru, Tamer Altınok, Bayram Metin, Hacı Hasan Esen Sep 2023

Comparison Of The Effects Of Alpha Lipoic Acid And Dexpanthenol In An Experimental Tracheal Reconstruction Animal Model, Murat Kuru, Tamer Altınok, Bayram Metin, Hacı Hasan Esen

Saudi Medical Journal

Objectives: To investigate the positive effects of intraperitoneal administration of alpha-lipolic acid (ALA) and dexpanthenol (DXP) on wound healing after tracheal surgery in rats. Methods: The study was carried out at Necmettin Erbakan University, Konya, Turkey, from January 2014-2019. A total of 30 healthy and adult Sprague-Dawley type female rats were included in the study. For the experiment, rats were randomly divided into 3 groups: ALA group (n=10), DXP group (n=10), and control group (n=10). After trachea surgery, 100 mg/kg/day ALA was given to group ALA and 100 mg/kg/day intraperitoneal DXP to group DXP for 15 days, and the rats …


Predictive Value Of Ferritin, Glucose, Urea, And Creatinine For Covid-19 Severity And Mortality In Patients From Asir, Saudi Arabia, Ahmad A. Shaikh, Turki A. Mubasher, Mohammed H. Makkawi, Sultan Z. Alasmari Aug 2023

Predictive Value Of Ferritin, Glucose, Urea, And Creatinine For Covid-19 Severity And Mortality In Patients From Asir, Saudi Arabia, Ahmad A. Shaikh, Turki A. Mubasher, Mohammed H. Makkawi, Sultan Z. Alasmari

Saudi Medical Journal

Objectives: To correlate demographics, blood groupings, and laboratory characteristics of hospitalized COVID-19 patients with disease severity and outcomes. Methods: This study included 294 COVID-19 patients. Data on patient age, gender, laboratory results, clinical severity, mortality, comorbidities, and blood group were obtained from medical records retrospectively. Results: High levels of ferritin ( p <0.01), urea ( p <0.0001), and creatinine ( p <0.05) were detected in intensive care unit (ICU)-admitted patients. Ferritin ( p <0.05), glucose ( p <0.0001), urea ( p <0.0001), and creatinine ( p <0.0001) were significantly higher in non-survivor compared to survivor COVID-19 patients. Predictors for ICU admission among patients were ferritin (odd ratio [OR]=0.999, p =0.0055) and urea (OR=0.991, p =0.0001). Predictors for mortality were: age (OR=0.963, p =0.0001), ferritin (OR=0.999, p =0.0149), glucose (OR=0.993, p =0.0001), urea (OR=0.976, p =0.0001), and creatinine (OR=0.556, p =0.0001). The most reliable laboratory parameters in predicting mortality were: age (area under the curve [AUC]=0.685, p <0.0001), ferritin (AUC=0.610, p <0.05), glucose (AUC=0.681, p <0.0001), urea (AUC=0.856, p <0.0001), and creatinine (AUC=0.823, p <0.0001). Conclusion: High ferritin, glucose, urea, and creatinine levels may predict poor outcomes in COVID-19 patients. These findings could help predict admissions to the ICU and mortality among such patients.


The Effect Of Covid-19 Pandemic On Antibiotic Usage During Pregnancy, Eman Bahaa, Latifa A. Fakhroo, Nawal Dayoub Aug 2023

The Effect Of Covid-19 Pandemic On Antibiotic Usage During Pregnancy, Eman Bahaa, Latifa A. Fakhroo, Nawal Dayoub

Saudi Medical Journal

Objectives: To investigated the usage of antibiotic during pregnancy before and during COVID-19 pandemic in Kingdom of Bahrain. Methods: This was a retrospective study of antibiotic usage in 2 groups of patients. The first group was 280 patients who attended the in active labor room pre-COVID pandemic. The second group was 193 patients who attended the labor room after the COVID-19 pandemic. Most of the data discussed below explores the impact of COVID-19 infection before the development of full vaccinations against COVID-19 in Bahrain. Results: The analysis confirmed higher usage of antibiotics during pregnancy post-COVID-19 outbreak (27.9% vs [versus] 5%), …


Antenatal Steroid As An Independent Risk Factor For Vitamin K2 Deficiency In Newborns: A Chinese Single-Center, Retrospective Study, Ling Liu, Chao-Hong Chen, Shi-Wen Rong, Shao-Zhu Lin, Na-Li Cai, Dang Ao Aug 2023

Antenatal Steroid As An Independent Risk Factor For Vitamin K2 Deficiency In Newborns: A Chinese Single-Center, Retrospective Study, Ling Liu, Chao-Hong Chen, Shi-Wen Rong, Shao-Zhu Lin, Na-Li Cai, Dang Ao

Saudi Medical Journal

Objectives: To identified vitamin K2 deficiency rate and risk factors among newborns in China and assess the importance of high-risk maternal intakes of vitamin K2. Methods: This retrospective study was performed at the Neonatology Department, the Affiliated Hospital of Guangdong Medical University, China. Routinely collected mother-neonate hospitalization data from July 2020 to January 2021 were analyzed. In total, data from 200 neonates who had completed vitamin K2 tests were utilized to assess the prevalence of vitamin K2 deficiency and identify the potential risk factors. According to the vitamin K2 level, the neonates were divided into 2 groups: cases (vitamin K2 …


In This Issuereview Articleoriginal Articles Aug 2023

In This Issuereview Articleoriginal Articles

Saudi Medical Journal

No abstract provided.


Obesity Management In The Saudi Population, Aljohrah Aldubikhi Aug 2023

Obesity Management In The Saudi Population, Aljohrah Aldubikhi

Saudi Medical Journal

Obesity is an alarming public health concern and needs to be addressed promptly in the Kingdom of Saudi Arabia. Sedentary lifestyle, changes in dietary intake and choice, culture, gender, climatic conditions and, lately, COVID-19 have contributed to obesity as a near epidemic in the Kingdom of Saudi Arabia. Interventions targeting obesity includes lifestyle management, pharmacotherapy, and surgery. Lifestyle interventions qualify as first-line therapies. Diets include a low-fat diet, low-calorie diet, low-carbohydrate diet, high-protein diet, and low-glycemic-index diet. Diet and exercise interventions can have a huge impact on weight loss. Pharmacotherapy is considered a treatment option at a later stage. Surgery …


Acinetobacter Baumannii: A Multidrug-Resistant Pathogen, Has Emerged In Saudi Arabia, Jehad A. Aldali Aug 2023

Acinetobacter Baumannii: A Multidrug-Resistant Pathogen, Has Emerged In Saudi Arabia, Jehad A. Aldali

Saudi Medical Journal

A significant opportunistic pathogen, Acinetobacter baumannii ( A. baumannii ) has evolved mechanisms of resistance to a wide variety of antimicrobials, including carbapenems. In this article, we assessed the prevalence, risk factors, antimicrobial sensitivity, and resistance mechanisms among A. baumannii in several locations in Saudi Arabia. Hospital-acquired infections caused by A. baumannii were prevalent in the country due to a variety of reasons, such as the high number of critically ill patients, the frequency of gastrointestinal colonization, and the widespread use of antimicrobial medications. There has been an increase in the frequency of A. baumannii strains that are resistant to …


The Nlrp3 Inflammasome Rs35829419 C>A Polymorphism Is Associated With Type 2 Diabetes Mellitus In Saudi Arabia, Yahia A. Kaabi Aug 2023

The Nlrp3 Inflammasome Rs35829419 C>A Polymorphism Is Associated With Type 2 Diabetes Mellitus In Saudi Arabia, Yahia A. Kaabi

Saudi Medical Journal

Objectives: To investigate the frequency of NLRP3 gene rs35829419 C>A single-nucleotide polymorphism (SNP) in a Saudi Arabian population from Jazan (Southwest Saudi Arabia) and test its potential association with type 2 diabetes mellitus (T2DM). Methods: This case-control study included 546 volunteers (271 patients with T2DM and 275 healthy controls) recruited from outpatient clinics at Jazan University Hospital and King Fahad Central Hospital in Jazan, Saudi Arabia, between December 2021 and July 2022. Genomic DNA was extracted from all samples and genotyped for the NLRP3 rs35829419 C>A SNP using TaqMan technology. The association between the NLRP3 rs35829419 polymorphism and …


Autoimmune Diseases And Their Prevalence In Saudi Arabian Patients With Type 1 Diabetes Mellitus, Walaa M. Mohammedsaeed, Zain J. Alghamdi Aug 2023

Autoimmune Diseases And Their Prevalence In Saudi Arabian Patients With Type 1 Diabetes Mellitus, Walaa M. Mohammedsaeed, Zain J. Alghamdi

Saudi Medical Journal

Objectives: To evaluate the prevalence of autoimmune disorders among young and adult populations diagnosed with type 1 diabetes mellitus (T1DM) in Al-Madinah Al-Munawarah, Saudi Arabia, and assess the potential impact of these conditions on other comorbidities. Methods: A retrospective, descriptive study examined autoimmune disorders in T1DM youth and adults. A total of 2258 verified T1DMs were tested. Analyzed hospital and laboratory data. Autoimmune T1DM was investigated clinically and laboratory. Results: A total of 2258 T1DM adults, adolescents, and children were investigated; 500 (22.2%) were under 12, 540 (23.9%) were 13–17, and 1218 (53.9%) were 18 plus. Autoimmune with T1DM was …


Application Of Serum Gastric Function Markers And Digestive Tumor Indices To The Diagnosis Of Early Gastric Cancer And Precancerous Lesions, Zhu Yanan, Wang Juan, Wang Jun, Ma Xin, Wu Kejian, Wang Fangyu Aug 2023

Application Of Serum Gastric Function Markers And Digestive Tumor Indices To The Diagnosis Of Early Gastric Cancer And Precancerous Lesions, Zhu Yanan, Wang Juan, Wang Jun, Ma Xin, Wu Kejian, Wang Fangyu

Saudi Medical Journal

Objectives: To study the levels of carcinoembryonic antigen (CEA), carbohydrate antigen (CA) 199, CA724, CA242, pepsinogen (PG) I, PGII, gastrin-17 (G-17), the PGI/PGII ratio (PGR), as well as the expression of p27 and Ki67, in patients suffering from early gastric cancer and intraepithelial neoplasia and to provide new markers for the diagnosis of early gastric cancer and precancerous lesions. Methods: A retrospective study where the blood serum concentration of CEA, CA199, CA724, CA242, PGI, PGII, G-17 and PGR were tested and also the protein expression of p27 and Ki67 was detected in patients tissues by immunohistochemistry in the Gastrointestinal Endoscopy …


Establishing Local Diagnostic Reference Levels For Computed Tomography Examinations Using Size-Specific Dose Estimates, Faisal A. Alrehily, Khalid S. Alqahtani, Marwan H. Aljohani, Nawaf S. Alharbi, Reyan M. Alharbi, Osamah M. Abdulaal, Abdullah F. Alshamrani, Abdulrahman S. Alsaedi, Sadeq H. Al-Murshedi, Fahad H. Alhazmi Aug 2023

Establishing Local Diagnostic Reference Levels For Computed Tomography Examinations Using Size-Specific Dose Estimates, Faisal A. Alrehily, Khalid S. Alqahtani, Marwan H. Aljohani, Nawaf S. Alharbi, Reyan M. Alharbi, Osamah M. Abdulaal, Abdullah F. Alshamrani, Abdulrahman S. Alsaedi, Sadeq H. Al-Murshedi, Fahad H. Alhazmi

Saudi Medical Journal

Objectives: To establish local DRL (LDRL) for computed tomography (CT) examinations based on size-specific dose estimates (SSDEs), which consider patient size. The concept of diagnostic reference level (DRL) was introduced to limit patient exposure to unnecessary radiation. However, traditional DRL values do not consider patient size. Methods: Following institutional committee approval, data were collected from CT examinations of adult patients at Madinah General Hospital, Al Madinah Al Munawwarah, Saudi Arabia from January to March 2023. The SSDE was calculated for each patient using the effective diameter (D eff ). Results: The LDRLs of the brain, cervical spine, chest, thoracic spine …


The Usability Of Neopterin In Determining Disease Course In Covid-19, Duru Mıstanoglu Ozatag, Pınar Korkmaz, Havva Keskin, Havva Koçak Aug 2023

The Usability Of Neopterin In Determining Disease Course In Covid-19, Duru Mıstanoglu Ozatag, Pınar Korkmaz, Havva Keskin, Havva Koçak

Saudi Medical Journal

Objectives: To investigate the usability of neopterin in demonstrating the progression of COVID-19. As a result of uncontrolled activation of COVID-19 monocytes and macrophages, IFN gamma increases and the resulting inflammatory response causes organ damage. IFN released from T cells causes an increase in gamma neopterin levels. Therefore, measurement of neopterin levels can be used to indicate immune system activation and disease progression. Methods: The study was carried out prospectively in two different centers. The patients were divided into two groups (mild-moderate and severe) and clinical, laboratory, imaging findings and neopterin levels at hospitalization were compared. Results: 100 patients were …


What Are The Endometrial Cancer Risks And Trends Among Different African Descent Populations? Aug 2023

What Are The Endometrial Cancer Risks And Trends Among Different African Descent Populations?

Saudi Medical Journal

No abstract provided.


New Global Action Plan On Epilepsy And Other Neurological Disorders Published Aug 2023

New Global Action Plan On Epilepsy And Other Neurological Disorders Published

Saudi Medical Journal

No abstract provided.


Who Urges Countries To Invest In Drowning Prevention To Protect Children Aug 2023

Who Urges Countries To Invest In Drowning Prevention To Protect Children

Saudi Medical Journal

No abstract provided.


Which Women Should Receive More Than Mammograms To Screen For Breast Cancer? Aug 2023

Which Women Should Receive More Than Mammograms To Screen For Breast Cancer?

Saudi Medical Journal

No abstract provided.


Prevalence Of Extended-Spectrum Β-Lactamase And Carbapenem-Resistant Klebsiella Pneumoniae In Clinical Samples, Amela Dedeić Ljubović, Ðana Granov, Erna Husić, Džemilja Gačanović, Jasmina Halković, Azra Čamdžić Lab.Ing, Šejla Kotorić Keser, Svjetlana Loga Zec Aug 2023

Prevalence Of Extended-Spectrum Β-Lactamase And Carbapenem-Resistant Klebsiella Pneumoniae In Clinical Samples, Amela Dedeić Ljubović, Ðana Granov, Erna Husić, Džemilja Gačanović, Jasmina Halković, Azra Čamdžić Lab.Ing, Šejla Kotorić Keser, Svjetlana Loga Zec

Saudi Medical Journal

Objectives: To assess the prevalence of these resistant strains in the overall isolates of Klebsiella pneumoniae ( K. pneumoniae ) in hospital settings. Methods: This retrospective study was conducted from November 2020 to November 2021. The identification and antibiotic susceptibility testing were performed using standard laboratory methods according to the EUCAST standards. The detection of ESBL and carbapenemase production was performed using phenotypic methods such as E-test, combined-disk test with various inhibitors (ROSCO Diagnostica A/S), chromogenic medium for the detection of ESBL/carbapenemase-producing Enterobacteriaceae (CPE) isolates, and the VITEK 2 Compact system (BioMerieux). Results: 944 isolates of K. pneumoniae were detected …


Epidemiology Of Pediatric Trauma In Makkah, Kingdom Of Saudi Arabia: An Observational Cohort Study, Mansour M. Almalki, Mohammed E. Almalki, Nedaa Alsulaimani, Shahad Tariq, Taif Alqahtani, Fawaz Baalaraj, Mohammed Ageel Aug 2023

Epidemiology Of Pediatric Trauma In Makkah, Kingdom Of Saudi Arabia: An Observational Cohort Study, Mansour M. Almalki, Mohammed E. Almalki, Nedaa Alsulaimani, Shahad Tariq, Taif Alqahtani, Fawaz Baalaraj, Mohammed Ageel

Saudi Medical Journal

Objectives: To explore the epidemiology and patterns of pediatric trauma in addition to length of hospital stay and outcome. Methods: A single-center retrospective study of 605 patients aged 14 years and younger was carried out from January to December 2022. The study included all patients who experienced intentional or unintentional trauma aged 14 years or below in 2022 and excluded trauma that did not prompt an emergency room visit. Results: Most pediatric trauma cases involved boys (69.1%, n=418), and girls comprised only 30.9% (n=187). Trauma was most common in children one to 5 years old (41.5%, n=251). Falling from a …


Outcomes Of Emergency Colorectal Surgery In Elderly Population, Nahar A. Alselaim, Roaa Alsuhaibani, Sultanah Bin Gheshayan, Sara Albreakeit, Nada Alhassan, Rana Alharbi Jul 2023

Outcomes Of Emergency Colorectal Surgery In Elderly Population, Nahar A. Alselaim, Roaa Alsuhaibani, Sultanah Bin Gheshayan, Sara Albreakeit, Nada Alhassan, Rana Alharbi

Saudi Medical Journal

Objectives: To assess the outcomes of emergency colorectal surgeries in elderly patients over the age of 65 years. Methods: This is a retrospective chart review study. We studied 99 patients over the age of 65 years and 142 patients younger than 65 years who underwent emergency colorectal surgery at our institute. In this study, patient demographics, operative results, length of hospital stay, and survival were analyzed. Results: Emergency colorectal surgery was performed on a total of 145 men and 96 women. Patients over the age of 65 years were found to have a significantly greater proportion of pulmonary, cardiac, and …


The Remission Rate, Metabolic Changes, And Quality Of Life Assessment Among Patients With Type 2 Diabetes Post-Bariatric Surgery In Riyadh, Saudi Arabia: A Cross-Sectional Study, Lina I. Alnajjar, Mohammed A. Alzaben, Atheer A. Alghamdi, Munirah.O. Alomani, Maha S. Abbas, Rahaf F. Altammami, Sara A. Alabdullatif, Amira M. Youssef, Alaa A. Alhubaishi Jul 2023

The Remission Rate, Metabolic Changes, And Quality Of Life Assessment Among Patients With Type 2 Diabetes Post-Bariatric Surgery In Riyadh, Saudi Arabia: A Cross-Sectional Study, Lina I. Alnajjar, Mohammed A. Alzaben, Atheer A. Alghamdi, Munirah.O. Alomani, Maha S. Abbas, Rahaf F. Altammami, Sara A. Alabdullatif, Amira M. Youssef, Alaa A. Alhubaishi

Saudi Medical Journal

Objectives: To assess the remission rate, metabolic changes, and quality of life after bariatric surgery among Saudi patients with type 2 diabetes (T2DM). Methods: This cross-sectional study was conducted in 2 main centers in the Riyadh, Saudi Arabia. The study included patients with T2DM who underwent either laparoscopic sleeve gastrectomy (LSG) or Roux-en-Y gastric bypass (RYGB) surgery from 2014 to 2018. The remission rate was defined based on the American Diabetes Association (ADA) and the International Diabetes Federation (IDF) criteria. Quality of life was assessed using the World Health Organization Quality of Life (WHOQOL)-BREF. Results: A total of 232 patients …


Complications And Risk Factors Of Early-Onset Versus Late-Onset Gestational Diabetes Mellitus: A Cohort Study From Saudi Arabia, Salhah S. Alsulami, Kholoud A. Ghamri Jul 2023

Complications And Risk Factors Of Early-Onset Versus Late-Onset Gestational Diabetes Mellitus: A Cohort Study From Saudi Arabia, Salhah S. Alsulami, Kholoud A. Ghamri

Saudi Medical Journal

Objectives: To contribute to this discussion by comparing the complications associated with early-diagnosed versus (vs.) late-diagnosed gestational diabetes mellitus (GDM) for mothers and infants in order to provide baseline data that might guide future changes in the current recommendations for screening. Methods: The study compares the risk factors and complications for early- vs. late-diagnosed GDM in a cohort from Saudi Arabia. Prenatal, perinatal, postpartum, and neonatal variables were compared between the early vs. late-diagnosed GDM groups using information gathered from the patient’s hospital records. Results: Significant predictors of early-diagnosed GDM included pregestational BMI and GDM history. Additionally, early diagnosis of …


In This Issuereview Articleoriginal Articles Jul 2023

In This Issuereview Articleoriginal Articles

Saudi Medical Journal

No abstract provided.


Barriers And Facilitators To Physiotherapy Among Adult Orthopedic Patients At King Khalid University Hospital, Riyadh, Kingdom Of Saudi Arabia: A Cross-Sectional Study, Abdulmajeed A. Alzakri, Omar A. Alsultan, Mohammed N. Alhuqbani, Zyad A. Aldosari, Omar M. Alghadir, Omar A. Aldosari, Badr F. Alshehri, Khalid A. Alsaleh Jul 2023

Barriers And Facilitators To Physiotherapy Among Adult Orthopedic Patients At King Khalid University Hospital, Riyadh, Kingdom Of Saudi Arabia: A Cross-Sectional Study, Abdulmajeed A. Alzakri, Omar A. Alsultan, Mohammed N. Alhuqbani, Zyad A. Aldosari, Omar M. Alghadir, Omar A. Aldosari, Badr F. Alshehri, Khalid A. Alsaleh

Saudi Medical Journal

Objectives: To identify barriers and facilitators to physiotherapy adherence in adult patients who attended an orthopaedic clinic and underwent physical therapy at King Khalid University Hospital (KKUH), Riyadh, Saudi Arabia. Methods: This cross-sectional study was performed at KKUH between September 2022 and January 2023. After conducting a literature review, a survey questionnaire was created, and a pilot study was conducted to evaluate its validity and clarity. Patients were approached in the waiting areas of the outpatient clinics and provided with a consent form to participate in the study. Results: Ongoing pain, travel distance, and lack of transportation were common barriers …


Metabolic And Renal Outcomes Of Empagliflozin In Patients With Type 2 Diabetes Mellitus Attending Armed Forces Hospital In Saudi Arabia: Retrospective Cohort Study, Ali A. Alshahrani, Saeed M. Mashhour, Zayed S. Alkhtani, Yahya M. Alragea Jul 2023

Metabolic And Renal Outcomes Of Empagliflozin In Patients With Type 2 Diabetes Mellitus Attending Armed Forces Hospital In Saudi Arabia: Retrospective Cohort Study, Ali A. Alshahrani, Saeed M. Mashhour, Zayed S. Alkhtani, Yahya M. Alragea

Saudi Medical Journal

Objectives: To explore the effects of empagliflozin (25 mg) on metabolic and renal parameters in patients with type 2 diabetes mellitus (T2DM). Methods: This retrospective observational comparative study was conducted at a military hospital in southern Saudi Arabia. All adults (aged >18 years) with T2DM who attended diabetic clinics between October 2021 to March 2022 (6 months), with or without insulin treatment, were eligible for inclusion in the study. Results: Following the initiation of empagliflozin treatment, statistically significant reductions in patient weight (kg) were observed at 1, 3-5, and 6 months. In addition, low-density lipoprotein levels significantly decreased 3-5 months …


Does Fat Content Within Muscle Predict Risk Of Cognitive Decline? Jul 2023

Does Fat Content Within Muscle Predict Risk Of Cognitive Decline?

Saudi Medical Journal

No abstract provided.


Women And Girls Bear Brunt Of Water And Sanitation Crisis – New Unicef-Who Report Jul 2023

Women And Girls Bear Brunt Of Water And Sanitation Crisis – New Unicef-Who Report

Saudi Medical Journal

No abstract provided.


Current Controversies In The Management Of Patients With Indeterminate Thyroid Nodules, Saad M. Alqahtani Jul 2023

Current Controversies In The Management Of Patients With Indeterminate Thyroid Nodules, Saad M. Alqahtani

Saudi Medical Journal

The management of cytologically indeterminate thyroid nodules remains debatable as their malignancy is difficult to establish. Most nodules have benign postoperative histology, but an accurate assessment of their proclivity for malignant transformation is crucial. Numerous studies have investigated the effects of various tools, including clinical, radiological, and cytological features, as well as biochemical and molecular markers, on the management of these heterogeneous nodules. Collectively, strategies aim to treat malignant nodules and avoid unnecessary surgery for asymptomatic benign nodules. Currently, no clear guidelines for the optimal management of cytologically indeterminate thyroid nodules exist to determine whether a conservative approach with long-term …


Eosinophilic Esophagitis, Saad Alkhowaiter Jul 2023

Eosinophilic Esophagitis, Saad Alkhowaiter

Saudi Medical Journal

Eosinophilic esophagitis (EoE) is an atopic disease in which eosinophils infiltrate the esophageal mucosa and may result in a variety of upper gastrointestinal symptoms. Chief among these are dysphagia, heartburn, and food bolus obstruction in adults whereas children often present with abdominal pain or vomiting. Eosinophilic esophagitis is a chronic condition that if not detected and left untreated could lead to the development of subepithelial fibrosis and esophageal stenosis. The diagnosis of EoE is confirmed in a patient presenting with characteristic EoE symptoms, classic signs on endoscopy, and biopsy results showing >15 eosinophils/hpf. A number of useful treatments against EoE …