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Rate Of Glucose-6-Phosphate Dehydrogenase Deficiency In Neonatal Indirect Hyperbilirubinemia At A Private Tertiary Centre, Hussain M. Alhiwaishil, Mohammed A. Alghareeb, Ammar S. Alkhars, Taha H. Abdalla, Abdulhadi A. Almohsen, Abbas Al Mutair Oct 2024

Rate Of Glucose-6-Phosphate Dehydrogenase Deficiency In Neonatal Indirect Hyperbilirubinemia At A Private Tertiary Centre, Hussain M. Alhiwaishil, Mohammed A. Alghareeb, Ammar S. Alkhars, Taha H. Abdalla, Abdulhadi A. Almohsen, Abbas Al Mutair

Saudi Medical Journal

Objectives: To investigate the rate of hospitalized neonates with glucose-6-phosphate dehydrogenase (G6PD) deficiency presented with indirect hyperbilirubinemia at a private tertiary center in Al-Ahsa, Saudi Arabia, over 4 years and to compare the characteristics of G6PD-deficient and normal neonates admitted for indirect hyperbilirubinemia. Methods: The retrospective case control study was carried out at Almoosa Specialist Hospital, Al-Ahsa, Saudi Arabia. Data were collected from Yassasi Medical System from 2018-2021 and finalized in 2024. The study included 2 groups: G6PD-normal and G6PD-deficient neonates with indirect hyperbilirubinemia not having recognizable triggers of hemolysis. The analysis focused on serum bilirubin levels, direct bilirubin levels, …


Global Study Predicts Increases In Cancer Cases And Deaths Among Men, With Widening Disparities Based On Age And Countries’ Economic Status Oct 2024

Global Study Predicts Increases In Cancer Cases And Deaths Among Men, With Widening Disparities Based On Age And Countries’ Economic Status

Saudi Medical Journal

No abstract provided.


Fourteen African Countries, Key Partners Unite To Provide Critical Resources For Health In Who’S First-Ever Investment Round Oct 2024

Fourteen African Countries, Key Partners Unite To Provide Critical Resources For Health In Who’S First-Ever Investment Round

Saudi Medical Journal

No abstract provided.


The Association Of Liver Fibrosis And Chronic Kidney Disease In Patients With Metabolic Associated Fatty Liver Disease: A Cross-Sectional Study, Rehab Badawi, Sara Essam Hasby, Walaa Elkhalawany, Waleed Elrefaey, Nahla Ahmed Khalf, Hanaa Ibrahim Okda Oct 2024

The Association Of Liver Fibrosis And Chronic Kidney Disease In Patients With Metabolic Associated Fatty Liver Disease: A Cross-Sectional Study, Rehab Badawi, Sara Essam Hasby, Walaa Elkhalawany, Waleed Elrefaey, Nahla Ahmed Khalf, Hanaa Ibrahim Okda

Saudi Medical Journal

Objectives: To examine the relation between liver fibrosis and chronic kidney disease (CKD) in metabolic-associated fatty liver disease (MAFLD) patients and its risk factors. Methods: The current study was carried out at Tanta University Hospital, Tanta, Egypt, from May 2021 to January 2023 and included 84 MAFLD patients with CKD and 80 MAFLD patients without CKD. All participants had been examined by abdominal ultrasonography and transient elastography with controlled attenuation parameter. Results: Chronic kidney disease patients exhibited a greater incidence of fibrosis compared to patients without CKD (75.6% vs. 24.4%). Logistic analysis demonstrated that the presence of multiple health conditions, …


Characteristics And One-Year Outcomes Of Patients With Advanced Atrioventricular Block In Saudi Arabia: A Single-Center Retrospective Cohort Study, Wael A. Alqarawi, Abdulrahman S. Alarifi Oct 2024

Characteristics And One-Year Outcomes Of Patients With Advanced Atrioventricular Block In Saudi Arabia: A Single-Center Retrospective Cohort Study, Wael A. Alqarawi, Abdulrahman S. Alarifi

Saudi Medical Journal

Objectives: To report and describe the characteristics and outcomes of patients with advanced atrioventricular block (AVB) in Saudi Arabia. Methods: We included consecutive patients who underwent pacemaker implantation at King Khaled University Hospital, Riyadh, Saudi Arabia, for advanced AVB, which was defined as second degree type 2 AVB, third degree AVB, and symptomatic atrial fibrillation with slow ventricular response. The variable “young patient” was defined as age of 60 or less, based on guidelines recommending cardiac sarcoidosis (CS) evaluation at this age or younger. Results: Among 100 patients (median age: 71 males, 51%), 29 (29%) were young patients. Most patients …


A Parasite That Should Not Be Neglected In Geriatric Individuals: Entamoeba Histolytica, Selahattin Aydemir, Nuriz Ateş, Abdurrahman Ekici, Hasan Yilmaz Oct 2024

A Parasite That Should Not Be Neglected In Geriatric Individuals: Entamoeba Histolytica, Selahattin Aydemir, Nuriz Ateş, Abdurrahman Ekici, Hasan Yilmaz

Saudi Medical Journal

Objectives: To highlight the importance of neglected Entamoeba histolytica ( E. histolytica ) infections in the geriatric age group, which is an increasing proportion of the world’s population. Methods: This study was carried out between January 2022 and December 2023 at Van Yüzüncü Yıl University, Faculty of Medicine, Parasitology Laboratory, Van, Turkey. The study included 96 geriatric patients with diarrhea (geriatric group). Two different control groups (CGs) were also included in the study, comprising 92 patients aged 18-64 years with diarrhea as CG1 and 50 geriatric individuals without diarrhea and other gastrointestinal complaints as CG2. Samples were analysed macroscopically and …


Erratum Oct 2024

Erratum

Saudi Medical Journal

No abstract provided.


Exploring The Quality Of Life And Comorbidity Impact Among Patients With Systemic Lupus Erythematosus In Saudi Arabia, Roaa A. Aljohani, Ghada A. Aljanobi, Khaled Alderaan, Mohammed A. Omair Oct 2024

Exploring The Quality Of Life And Comorbidity Impact Among Patients With Systemic Lupus Erythematosus In Saudi Arabia, Roaa A. Aljohani, Ghada A. Aljanobi, Khaled Alderaan, Mohammed A. Omair

Saudi Medical Journal

Objectives: To explore the quality of life (QoL) of patients with systemic lupus erythematosus (SLE) and the factors affecting it. Methods: In this cross-sectional study, 269 patients diagnosed with SLE from multiple centers across different regions of Saudi Arabia were included. We used the LupusPRO1.8 QoL assessment tool. Additionally, comprehensive data regarding patient demographics, disease features, and associated comorbidities were collected for analysis. Results: The overall mean QoL score was 57.71±11.97, with the median value (interquartile range [IQR]) of 56.82 (48.62-66.65). The mean health-related QoL (HRQoL) score was 57.09±18.81, with the median (IQR) of 55.63 (44.04-70.19). Among HRQoL domains, the …


In This Issuesystematic Revieworiginal Articles Oct 2024

In This Issuesystematic Revieworiginal Articles

Saudi Medical Journal

No abstract provided.


Deaths From Advanced Lung Cancer Have Dropped Significantly Since Immunotherapy Became Standard-Of-Care Oct 2024

Deaths From Advanced Lung Cancer Have Dropped Significantly Since Immunotherapy Became Standard-Of-Care

Saudi Medical Journal

No abstract provided.


Global Strategic Preparedness And Response Plan Launched By Who To Contain Mpox Outbreak Oct 2024

Global Strategic Preparedness And Response Plan Launched By Who To Contain Mpox Outbreak

Saudi Medical Journal

No abstract provided.


Could Botox Make Walking Easier In Children With Cerebral Palsy? Sep 2024

Could Botox Make Walking Easier In Children With Cerebral Palsy?

Saudi Medical Journal

No abstract provided.


Right Lung Hypoplasia Associated With Polysplenia: A Case Report And Literature Review, Rayyan M. Almusally Sep 2024

Right Lung Hypoplasia Associated With Polysplenia: A Case Report And Literature Review, Rayyan M. Almusally

Saudi Medical Journal

Abstract Pulmonary agenesis is a very rare congenital abnormality that can be missed in a routine radiographic examination, which delays diagnosis until adulthood. It can be associated with other congenital malformations, such as valvular heart disease and gastrointestinal organ abnormalities. Computed tomography (CT) is a useful modality for its better delineation of pulmonary and vascular structures. The reported case here is for an adult male who presented with dextroposition of the heart and was found to have a unilobed right lung associated with polysplenia. This has not been previously reported in the literature.


Psychological Resilience And Well-Being Among A Sample Of Saudi, Bashayr A. Almutlaq, Lulu A. Almohaimeed, Soumaya A. Kahin, Modi S. Alsubaie Sep 2024

Psychological Resilience And Well-Being Among A Sample Of Saudi, Bashayr A. Almutlaq, Lulu A. Almohaimeed, Soumaya A. Kahin, Modi S. Alsubaie

Saudi Medical Journal

Abstract Objectives: To investigate the correlation between psychological resilience and well-being, considering various demographic factors within a Saudi society. Methods: This study was carried out in King Saud University, Riyadh, Saudi Arabia from January to March 2023. A total of 746 male and female participants aged 18 and above were surveyed. We used a comparative, descriptive, correlational research method to achieve the study objectives, utilizing Conner and Davidson’s resilience measure and Ryff’s well-being scale for data collection. The statistical methods employed included Spearman’s correlation coefficient, t-test, one-way analysis of variance (ANOVA), Mann-Whitney U, and Kruskal-Wallis tests. Results: The study revealed …


In This Issuesystematic Revieworiginal Articlescase Report Sep 2024

In This Issuesystematic Revieworiginal Articlescase Report

Saudi Medical Journal

No abstract provided.


Biological Studies Of The Activity Of Manuka Honey Against Carbapenem-Resistant Enterobacterales (Cre) Bacteria, Mamdouh A. Bukhari, Razaz A. Qamash, Rasha A. Bulkhi, Jehad A. Bifari, Omar S. Bakhsh, Khalid O. Hawsawi, Ehab Y. Matuure, Kamil A. Sulaimani, Ashwaq T. Hakim, Maher S. Mujahid Sep 2024

Biological Studies Of The Activity Of Manuka Honey Against Carbapenem-Resistant Enterobacterales (Cre) Bacteria, Mamdouh A. Bukhari, Razaz A. Qamash, Rasha A. Bulkhi, Jehad A. Bifari, Omar S. Bakhsh, Khalid O. Hawsawi, Ehab Y. Matuure, Kamil A. Sulaimani, Ashwaq T. Hakim, Maher S. Mujahid

Saudi Medical Journal

Objectives: To evaluate the potency of Manuka honey UMF +15 against Carbapenem-resistant Enterobacterales (CRE). Bacterial resistance is a worldwide problem that is increasing year by year, especially Carbapenem resistance. Alternatives to antibiotics are needed to both reduce costs, and to reduce the spread of antibiotic resistance, with the ultimate goal of saving lives. Methods: The efficacy of Manuka honey UMF +15 was tested by 2 methods; Well diffusion assay and minimum bactericidal concentration (MBC) against twenty Carbapenem-resistant isolates which collected from Makkah city hospitals during three months of study from 1st of September 2023 up to 1st of December 2023. …


Determination Of The Effectiveness Of The Three-Minute Nutrition Screening (3-Minns) Tool In Adult Patients Hospitalized In A Cardiology Clinic, Asli Onur Canaydin, Habibe Sahin Sep 2024

Determination Of The Effectiveness Of The Three-Minute Nutrition Screening (3-Minns) Tool In Adult Patients Hospitalized In A Cardiology Clinic, Asli Onur Canaydin, Habibe Sahin

Saudi Medical Journal

Objectives: To determine the efficacy of the 3-Minute Nutrition Screening (3-MinNS) tool in adults hospitalized for cardiovascular diseases. Methods: In this descriptive cross-sectional study of 759 cardiovascular disease patients in Erciyes University Cardiology Clinic, anthropometric measurements and some routine biochemical parameters were recorded, and nutrition screening tools were used to determine malnutrition status. The power of 3-MinNS to detect malnutrition in cardiovascular diseases patients was calculated. Results: There was a strong positive correlation between 3-MinNS and Nutrition Risk Screening-2002 (NRS-2002) (r=0.719, p <0.001). A moderate agreement was found between 3-MinNS and NRS-2002 (κ=0.496, p <0.001). The sensitivity, specificity, and AUC of 3-MinNS were 79.1%, 75.0%, and 0.851, respectively, and it was determined to be a moderately effective nutrition screening tool that can be used to identify malnutrition in patients with cardiovascular diseases. Conclusion: The 3-MinNS is a moderately effective nutrition screening tool that can be administered within the first 24 hours of hospitalization in patients with cardiovascular diseases.


Monoexponential And Advanced Diffusion-Weighted Imaging For Hepatic Fibrosis Staging Based On High Inter-Examiner Reliability, Lesheng Huang, Qian Wei, Hui Peng, Wanchun Zhang, Jiahui Tang, Tianzhu Liu Sep 2024

Monoexponential And Advanced Diffusion-Weighted Imaging For Hepatic Fibrosis Staging Based On High Inter-Examiner Reliability, Lesheng Huang, Qian Wei, Hui Peng, Wanchun Zhang, Jiahui Tang, Tianzhu Liu

Saudi Medical Journal

Abstract Objectives: To determine the diagnostic efficiencies of multiple diffusion-weighted imaging (DWI) techniques for hepatic fibrosis (HF) staging under the premise of high inter-examiner reliability. Methods: Participants with biopsy-confirmed HF were recruited and divided into the early HF (EHF) and advanced HF (AHF) groups; healthy volunteers (HVs) served as controls. Two examiners analyzed intravoxel incoherent motion (IVIM) using the IVIM-DWI and diffusion kurtosis imaging (DKI) models. Intravoxel incoherent motion-DWI, DKI, and diffusion tensor imaging parameters with intraclass correlation coefficients (ICCs) of ≥0.6 were used to create regression models: HVs vs. EHF and EHF vs. AHF. Results: We enrolled 48 HVs, …


Physician Practices In Referring Rheumatoid Hand And Thumb Carpometacarpal Arthritis Cases To Hand Surgeons, Zahir T. Fadel, Zainalabden E. Jefri, Hussain A. Alkhalifah, Raghad A. Alzahrani, Mohammed B. Ashi, Osama A. Samargandi Sep 2024

Physician Practices In Referring Rheumatoid Hand And Thumb Carpometacarpal Arthritis Cases To Hand Surgeons, Zahir T. Fadel, Zainalabden E. Jefri, Hussain A. Alkhalifah, Raghad A. Alzahrani, Mohammed B. Ashi, Osama A. Samargandi

Saudi Medical Journal

Abstract Objectives: To investigate the referral practices across different medical specialties and identify possible barriers to hand surgery referral. Rheumatoid hand deformities (RHDs) and thumb carpometacarpal (CMC) arthritis may require surgery once deformities occur. However, in Saudi Arabia, the rate of referrals to hand surgeons remains low. Methods: This was a cross-sectional study that included 102 consultants of family medicine, rheumatology, and orthopedics across various regions of Saudi Arabia. A total of 30 institutions were contacted and requested to distribute a survey questionnaire to their physicians; these institutions included 8 private hospitals, 16 government hospitals, and 6 primary healthcare centers. …


What Do You Do With A Normal Appearing Appendix?: A National Study Of Pediatric Surgeons, Yasser S. Alfraih, Renad Almutawa Sep 2024

What Do You Do With A Normal Appearing Appendix?: A National Study Of Pediatric Surgeons, Yasser S. Alfraih, Renad Almutawa

Saudi Medical Journal

Abstract Objectives: Surgeons may encounter a grossly normal appearing appendix in a patient with clinically suspected appendicitis. The purpose of this study is to determine the practice of pediatric surgeons in Saudi Arabia when this is encountered, and determine the reasons behind their decision making. Methods: An electronic survey was sent to all pediatric surgeons in Saudi Arabia. Data points collected included demographics, peri-operative imaging preference, and personal practice when managing an intra-operative grossly normal appendix in symptomatic children. Results: A total of 105 responses were obtained yielding a response rate of 33.8% The majority of respondents, 88 (87.1%) would …


The Influence Of Social, Demographic And Economic Factors On Fertility Trends In Gulf Cooperation Council Countries: A Longitudinal Time Trend Analysis-1980-2021, Sultan A. Meo, Narmeen Shaikh, Anusha S. Meo Sep 2024

The Influence Of Social, Demographic And Economic Factors On Fertility Trends In Gulf Cooperation Council Countries: A Longitudinal Time Trend Analysis-1980-2021, Sultan A. Meo, Narmeen Shaikh, Anusha S. Meo

Saudi Medical Journal

Abstract Objectives: To analyze the fertility rate trends in the GCC countries and their association with socioeconomic factors so that policymakers may use the study findings for future healthcare plans. Methods: Total population, crude death rate, life expectancy, literacy rate, human development index (HDI), female employment, unemployment rate, urbanisation, gross domestic product (GDP) per capita and inflation were chosen as possible predictors of TFR trends. The data were collected for the Global Burden of Disease 2021 study and other official databases such as the World Bank, the United Nations Development Program and Our World in Data for the 6 Gulf …


Middle East Immunology Summit Of The Gulf Cooperation Council Association Of Immunology And Rheumatology (Gcc Air), 2023 Dubai, United Arab Emirate. Scientific Abstracts And Case Reports, Ahmed S. Zayat, Saadeya Naji, Omar Syed, Adeeba Al-Herz, Ahmed Elasareeri, Mira Merashli, Mahdi Abusalameh, Waleed Hafiz, Elsadeg Sharif, Martin Lee, Fahdah Alokaily, Suad Hannawi Sep 2024

Middle East Immunology Summit Of The Gulf Cooperation Council Association Of Immunology And Rheumatology (Gcc Air), 2023 Dubai, United Arab Emirate. Scientific Abstracts And Case Reports, Ahmed S. Zayat, Saadeya Naji, Omar Syed, Adeeba Al-Herz, Ahmed Elasareeri, Mira Merashli, Mahdi Abusalameh, Waleed Hafiz, Elsadeg Sharif, Martin Lee, Fahdah Alokaily, Suad Hannawi

Saudi Medical Journal

No abstract provided.


Do Dieticians Have Weight Biases Towards Themselves And Others? Sep 2024

Do Dieticians Have Weight Biases Towards Themselves And Others?

Saudi Medical Journal

No abstract provided.


Who Director-General Declares Mpox Outbreak A Public Health Emergency Of International Concern Sep 2024

Who Director-General Declares Mpox Outbreak A Public Health Emergency Of International Concern

Saudi Medical Journal

No abstract provided.


Who Prequalifies The First Self-Test For Hepatitis C Virus Sep 2024

Who Prequalifies The First Self-Test For Hepatitis C Virus

Saudi Medical Journal

No abstract provided.


Geriatric Nutritional Risk Index Predicts Postoperative Delirium In Elderly: A Meta-Analysis, Siye Xie, Qi Wu Sep 2024

Geriatric Nutritional Risk Index Predicts Postoperative Delirium In Elderly: A Meta-Analysis, Siye Xie, Qi Wu

Saudi Medical Journal

Objectives: To review current evidence on using the geriatric nutritional risk index (GNRI) in predicting postoperative delirium (POD) in elderly patients. Methods: The literature search was performed in core databases to include all the cohort studies on the association between GNRI and risk of POD for further meta-analysis. Results: A total of 6 studies with 4242 patients underwent this meta-analysis, which showed that the risk of POD was higher in patients with moderate and high GNRI than the ones with low GNRI (odds ratio [OR]=2.04, 95% confidence interval [CI] [1.58, 2.64], p <0.001), and moderate and high GNRI significantly increased the risk of POD in patients of 60 to 75 years or above [OR=1.98, 95%CI (1.49, 2.62), p <0.001; OR=2.79, 95%CI (1.38, 5.64), p =0.004, respectively]. Conclusion: Therefore, moderate and high GNRI increased the risk of POD in elderly patients.


Comparative Analysis Of Nutritional Quality And Microbial Contamination In Camel Milk: Evaluating Safety And Public Health Risks Between Camel Milk Obtained From Street Vendors And Farms In Saudi Arabia, Nisreen M. Abdulsalam, Ebtehal M. Alghamdi Sep 2024

Comparative Analysis Of Nutritional Quality And Microbial Contamination In Camel Milk: Evaluating Safety And Public Health Risks Between Camel Milk Obtained From Street Vendors And Farms In Saudi Arabia, Nisreen M. Abdulsalam, Ebtehal M. Alghamdi

Saudi Medical Journal

Objectives: To evaluate the nutritional quality and microbial contamination of raw camel milk sourced from street vendors and compare it with milk obtained from farms, with a particular emphasis on pathogenic organisms. Methods: Twenty samples were systematically collected from street vendors and farms between July 2022 and February 2023 and analyzed at King Fahad Medical Research Centre and the Pharmacy College, King Abdulaziz University, Jeddah, Saudi Arabia. The microbial analysis employed culture-dependent techniques for colony-forming unit analysis and isolation of microbial colonies from milk samples. Microbial identification utilized advanced methods, including VITEK-MS equipment and the MALDI-TOF technique. The chemical composition …


Is Postoperative Adjuvant Radiotherapy Necessary For Patients With Esophageal Cancer After Neoadjuvant Chemoradiotherapy?: An Analysis Based On The Seer Database, Yuhao Su, Yajing Wang, Chanjun Zhen, Wenwen Bai, Liyuan Fu, Yibing Liu, Ping Zhang, Zhiguo Zhou Sep 2024

Is Postoperative Adjuvant Radiotherapy Necessary For Patients With Esophageal Cancer After Neoadjuvant Chemoradiotherapy?: An Analysis Based On The Seer Database, Yuhao Su, Yajing Wang, Chanjun Zhen, Wenwen Bai, Liyuan Fu, Yibing Liu, Ping Zhang, Zhiguo Zhou

Saudi Medical Journal

Objectives: To evaluate the outcomes of adjuvant radiotherapy in patients with esophageal cancer (EC) who underwent esophagectomy following neoadjuvant chemoradiotherapy (NCRT). Methods: The data of EC patients who received adjuvant therapy after NCRT between 2004 to 2019 was retrieved from the SEER database. The patients were split into the adjuvant radiotherapy with or without chemotherapy (RT±CT) and the adjuvant chemotherapy (CT) groups. The process of propensity score matching (PSM) was employed. Results: Following PSM, 157 patients in total were recruited in each treatment group. There were no significant variations in either overall survival (OS) or cancer-specific survival (CSS) between the …


Electronic Device Usage Among Preschool Children And Its Association With Mental Health Status In Saudi Arabian Kindergartens, Siham O. Al-Mehmadi, Abdulrahman T. Halawani, Mrnan T. Sulaimani, Tamim O. Al-Mehmadi Sep 2024

Electronic Device Usage Among Preschool Children And Its Association With Mental Health Status In Saudi Arabian Kindergartens, Siham O. Al-Mehmadi, Abdulrahman T. Halawani, Mrnan T. Sulaimani, Tamim O. Al-Mehmadi

Saudi Medical Journal

Abstract Objectives: To estimate the prevalence of electronic device usage and its association with mental health status among preschool children aged 3-6 years. Methods: A cross-sectional study was conducted among preschool children aged 3-6 years in kindergartens in Makkah city in 2023-2024, using an electronic questionnaire. An Arabic version of the Strengths and Difficulties Questionnaire was used to assess mental health. Results: We recruited a total of 399 children. The prevalence of electronic device usage was 91.5%. The number of hours spent using electronic devices ranged from 0 to 12 hour (h)/day, with a mean of 3.1 h/day. We found …


Newborn Hearing Screening In Eastern Saudi Arabia: A Tertiary Hospital Experience Sep 2024

Newborn Hearing Screening In Eastern Saudi Arabia: A Tertiary Hospital Experience

Saudi Medical Journal

Abstract Objectives: To analyze the performance of a leading institution in implementing newborn hearing screening and address two key areas: the knowledge gap in screening practice and the prevalence of permanent sensorineural hearing loss in Saudi Arabia. Methods: We analyzed the prevalence of hearing impairment in all live births at King Fahad Hospital of the University, Al Khobar, Saudi Arabia, from September 2018 to June 2022. Automated auditory brainstem response was used for both initial screening and rescreening. Newborns who failed the rescreening underwent a diagnostic evaluation. We assessed the coverage of initial screening, the rate of lost follow-up, referrals …