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The Superior Gluteal Artery Perforator Flap For Reconstruction Of Sacral Sores, Weijian Chen, Bo Jiang, Jiaju Zhao, Peiji Wang Oct 2016

The Superior Gluteal Artery Perforator Flap For Reconstruction Of Sacral Sores, Weijian Chen, Bo Jiang, Jiaju Zhao, Peiji Wang

Saudi Medical Journal

This report describes our experiences using the superior gluteal artery perforator (SGAP) flaps for reconstruction of 2 sacral sore cases. A 47-year-old female patient and a 38-year-old man with sacral sores were treated in our unit. The size of the defects were approximately 5×6 cm 2 and 8×9 cm 2 , the defects were repaired by SGAP flaps. The size of designed was SGAP flaps varied from 7×20 to 9×16 cm 2 . All flaps survived and healed primary, the texture, functions, and appearance of flaps were satisfactory, and also without region dysfunction of donor and recipient sites. The SGAP …


The Saudi Clinical Practice Guideline For The Management Of Overweight And Obesity In Adults, Assim A. Alfadda, Madhawi M. Al-Dhwayan, Abdulhameed A. Alharbi, Nawal M. Al-Qahtani, Saad H. Alzahrani, Wedad M. Bardisi, Reem M. Sallam, John J. Riva, Jan L. Brożek, Holger J. Schünemann, Ainsley Moore Oct 2016

The Saudi Clinical Practice Guideline For The Management Of Overweight And Obesity In Adults, Assim A. Alfadda, Madhawi M. Al-Dhwayan, Abdulhameed A. Alharbi, Nawal M. Al-Qahtani, Saad H. Alzahrani, Wedad M. Bardisi, Reem M. Sallam, John J. Riva, Jan L. Brożek, Holger J. Schünemann, Ainsley Moore

Saudi Medical Journal

Objective: To assist healthcare providers in evidence-based clinical decision-making for the management of overweight and obese adults in Saudi Arabia. Methods: The Ministry of Health, Riyadh, Kingdom of Saudi Arabia assembled an expert Saudi panel to produce this clinical practice guideline in 2015. In collaboration with the methodological working group from McMaster University, Hamilton, Canada, using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach, which describes both the strength of recommendation and the quality of evidence Results: After identifying 11 questions, corresponding recommendations were agreed upon as guidance for the management of overweight and obese adults. These included …


Genetic Influence On Circulating Vitamin D Among Saudi Arabians, Mir Sadat-Ali, Haifa A. Al-Turki, Mohammed Q. Azam, Abdulmohsen H. Al-Elq Sep 2016

Genetic Influence On Circulating Vitamin D Among Saudi Arabians, Mir Sadat-Ali, Haifa A. Al-Turki, Mohammed Q. Azam, Abdulmohsen H. Al-Elq

Saudi Medical Journal

Objectives To examine the effect of most common studied single nucleotide polymorphisms (SNP) on serum 25-hydroxyvitamin D (25OHD) levels in Saudi Arabian population. Method A cross-sectional observational study was carried out between July 2014 and October 2015, at King Fahd Hospital of the University (KFHU), Al-Khobar, Kingdom of Saudi Arabia. After informed consent, blood samples from 283 subjects living in the Eastern province were collected for 25-OHD measurement and genetic analysis of SNPs in vitamin D receptor (VDR) [rs2228570 and rs1544410], Cytochrome, P450 family 2 (CYP2R1) [rs10741657 and rs1993116], and Group-specific components (GC) [rs2282679 and rs4588]. Results Vitamin D deficiency …


Vitamin D Deficiency And Biochemical Variations Among Urban Saudi Adolescent Girls According To Season, Riad A. Sulimani, Ashry G. Mohammed, Assim A. Alfadda, Suliman N. Alshehri, Abdulaziz M. Al-Othman, Nasser M. Al-Daghri, David A. Hanley, Aliya A. Khan Sep 2016

Vitamin D Deficiency And Biochemical Variations Among Urban Saudi Adolescent Girls According To Season, Riad A. Sulimani, Ashry G. Mohammed, Assim A. Alfadda, Suliman N. Alshehri, Abdulaziz M. Al-Othman, Nasser M. Al-Daghri, David A. Hanley, Aliya A. Khan

Saudi Medical Journal

Objectives: To determine seasonal variations in the vitamin D status of Saudi adolescent girls in Riyadh, Kingdom of Saudi Arabia (KSA) and its effect in biochemical and clinical characteristics. Methods: In this prospective study, a total of 2000 Saudi females aged 12-18 years from different schools in Riyadh, KSA participated and submitted a generalized questionnaire with clinical information. Fasting blood samples were obtained in 1618 subjects for the winter season (December to February) and only 499 subjects returned to submit fasting blood samples for the summer season (June-August). Circulating serum 25(OH)D, parathyroid hormone (PTH), and other biomarkers of bone remodeling …


Do Healthier Foods Cost More In Saudi Arabia Than Less Healthier Options?, Ibrahim M. Gosadi, Muner A. Alshehri, Saud H. Alawad Sep 2016

Do Healthier Foods Cost More In Saudi Arabia Than Less Healthier Options?, Ibrahim M. Gosadi, Muner A. Alshehri, Saud H. Alawad

Saudi Medical Journal

Objectives: To investigate whether healthy foods in Saudi Arabia cost more compared with less healthy options. Method: This is a cross-sectional study conducted in Riyadh, Saudi Arabia during June and July 2015. The study targeted well-known market chains in the city of Riyadh. The selection of food items was purposive to include healthy and less healthy food items in each category. Price, caloric value, salt, fat, sugar, and fiber contents for each food item were collected. To test for the correlation between nutritional contents and average price, Spearman’s correlation coefficients were calculated. The Mann-Whitney U test was used to test …


A Review Of Glycemic Efficacy Of Liraglutide Once Daily In Achieving Glycated Hemoglobin Targets Compared With Exenatide Twice Daily, Or Sitagliptin Once Daily In The Treatment Of Type 2 Diabetes, Khalid Z. Alshali, Abdullah M. Karawagh Aug 2016

A Review Of Glycemic Efficacy Of Liraglutide Once Daily In Achieving Glycated Hemoglobin Targets Compared With Exenatide Twice Daily, Or Sitagliptin Once Daily In The Treatment Of Type 2 Diabetes, Khalid Z. Alshali, Abdullah M. Karawagh

Saudi Medical Journal

Incretin-based therapies such as glucagon-like peptide-1 (GLP-1) receptor agonists (RA) and dipeptidyl peptidase-4 (DPP-4) inhibitors have gained prominence in recent years for the treatment of type 2 diabetes (T2D). Such therapies offer the potential to stimulate endogenous insulin activity in proportion to circulating glucose levels; thereby, lowering the risk of hypoglycemic episodes. The synthetic GLP-1 RA exenatide, the human GLP-1 RA liraglutide, and the DPP-4 inhibitor sitagliptin are the first agents in their respective classes to be approved for the treatment of T2D and their efficacy and safety has been studied extensively in clinical trials. This article reviewed the efficacy …


Chronic Periodontitis And Smoking Prevalence And Dose-Response Relationship, Shahrukh Khan, Taimur Khalid, Kamran H. Awan Aug 2016

Chronic Periodontitis And Smoking Prevalence And Dose-Response Relationship, Shahrukh Khan, Taimur Khalid, Kamran H. Awan

Saudi Medical Journal

Objectives: To determine the prevalence and dose-response relationship of chronic periodontitis among smokers in Pakistan. Methods: This is a cross-sectional study among participants seeking dental care in Karachi Medical and Dental College, Karachi, Pakistan. A total of 443 participants with a mean age of 44.3 (±6.5) participated in the study from April 2011 to December 2011. Males comprised 64.7%, and females comprised 35.2%. Participants were interviewed on social demographics and oral habits. Participants with shallow pockets (3.5-5.5 mm) and deep pockets (>5.5 mm) were considered suffering from chronic periodontitis. The characteristics of participants were assessed using frequency distribution for …


Identification Of Candida Species And Susceptibility Testing With Sensititre Yeastone Microdilution Panel To 9 Antifungal Agents, Emine Kucukates, Nuh N. Gultekin, Zeynep Alisan, Nur Hondur, Recep Ozturk Jul 2016

Identification Of Candida Species And Susceptibility Testing With Sensititre Yeastone Microdilution Panel To 9 Antifungal Agents, Emine Kucukates, Nuh N. Gultekin, Zeynep Alisan, Nur Hondur, Recep Ozturk

Saudi Medical Journal

Objectives: To determine the species incidence and susceptibility pattern to 9 antifungal agents of yeasts isolated from various clinical specimens of colonized or infected patients treated in the coronary and surgical intensive care units (ICU). Methods: A total of 421 ICU patients were treated at the Cardiology Institute, Istanbul University, Istanbul, Turkey between June 2013 and May 2014, and 44 Candida species were isolated from blood, urine, endotracheal aspiration fluid, sputum, and wounds of 16 ICU patients. Identification of Candida was performed using CHROMagar. Antifungal susceptibility was determined by a Sensititre YeastOne colorimetric microdilution panel. Results: Candida albicans ( C. …


Outpatient Admissions And Hospital Costs Of Syrian Refugees In A Turkish University Hospital, Bernard Tahirbegolli, Sabanur Çavdar, Esin Çetinkaya Sümer, Sıdıka I. Akdeniz, Suphi Vehid Jul 2016

Outpatient Admissions And Hospital Costs Of Syrian Refugees In A Turkish University Hospital, Bernard Tahirbegolli, Sabanur Çavdar, Esin Çetinkaya Sümer, Sıdıka I. Akdeniz, Suphi Vehid

Saudi Medical Journal

Objectives: To examine the most frequent admitted polyclinics, diagnoses, and the costs of Syrian refugee patient in a Turkish university hospital in the metropolitan city of Istanbul, Western part of Turkey. Methods: Research methodology consist of analyzing outpatient admissions to the Hospital Polyclinics of Faculty of Medicine, Istanbul University, Cerrahpasa, Istanbul, Turkey from January-June 2014. We carried out diagnosis groups as classified in the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision, Australian Modification, and analyzed the hospital cost of first admission through records based in the hospital information system. Results: Median age of 251 Syrian refugee …


Severe Subtype Of Alopecia Areata Is Highly Associated With Thyroid Autoimmunity Jun 2016

Severe Subtype Of Alopecia Areata Is Highly Associated With Thyroid Autoimmunity

Saudi Medical Journal

Objectives: To assess the significance of thyroid autoimmune screening in alopecia areata (AA) patients in Saudi population, and to determine whether there is a difference in thyroid autoimmune susceptibility between mild and severe AA. Methods: In a prospective case-control study, we included 50 alopecia totalis (AT) and alopecia universalis (AU) patients, 50 age- and gender-matched patients with localized AA, and 50 age- and gender- matched healthy subjects between March 2015 and August 2015. Patients with AA were consecutively recruited from the hair disorders out-patient clinic of King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia. Results: Thyroid autoantibodies (TAAs) were …


Spontaneous Ileostomy Closure, Mohammad S. Alyami, Peter W. Lundberg, Eddy G. Cotte, Olivier J. Glehen Jun 2016

Spontaneous Ileostomy Closure, Mohammad S. Alyami, Peter W. Lundberg, Eddy G. Cotte, Olivier J. Glehen

Saudi Medical Journal

Iatrogenic ileostomies are routinely placed during colorectal surgery for the diversion of intestinal contents to permit healing of the distal anastomosis prior to elective reversal. We present an interesting case of spontaneous closure of a diverting ileostomy without any adverse effects to the patient. A 65-year-old woman, positive for hereditary non-polyposis colorectal cancer type-I, with locally invasive cancer of the distal colon underwent en-bloc total colectomy, hysterectomy, and bilateral salpingoophorectomy with creation of a proximal loop ileostomy. The ostomy temporarily closed without reoperation at 10 weeks, after spontaneously reopening, it definitively closed, again without surgical intervention at 18 weeks following …


Vitamin D Status And Insulin Resistance Among Young Obese Saudi Females, Hala M. Abdelkarem, Mervat A. El-Sherif, Sahar B. Gomaa May 2016

Vitamin D Status And Insulin Resistance Among Young Obese Saudi Females, Hala M. Abdelkarem, Mervat A. El-Sherif, Sahar B. Gomaa

Saudi Medical Journal

Objectives: To evaluate the association of vitamin D level with insulin resistance, among healthy student’s obese women, and to identify factors that may elucidate this association. Methods: One hundred and forty-seven female students between the age group of 18 and 25 years were included in this cross-sectional study, and the related socio-demographic and anthropometric data were obtained. They were selected randomly from Aljouf University, Sakaka, Saudi Arabia between November 2013 and June 2014. Serum 25-hydroxy vitamin D (25[OH]D), glucose, insulin was measured and insulin resistance was calculated using the insulin resistance index (HOMA-IR). Results: The results showed the percentage of …


Knowledge, Awareness, Attitudes And Sources Of Vitamin D Deficiency And Sufficiency In Saudi Children, Fatimah M. Alshamsan, Bassam S. Bin-Abbas May 2016

Knowledge, Awareness, Attitudes And Sources Of Vitamin D Deficiency And Sufficiency In Saudi Children, Fatimah M. Alshamsan, Bassam S. Bin-Abbas

Saudi Medical Journal

Objectives: To examine the awareness, knowledge, and attitudes regarding vitamin D and its sources among Saudi Arabian children. Methods: One hundred patients (vitamin D-deficient children) and 100 healthy children participated in the study. Participants were interviewed separately on topics including their awareness, knowledge, and attitudes regarding vitamin D using multiple-choice, and short-answer questions. This prospective, cross-sectional study was performed on children and adolescents between January 2011 and December 2011 at the Security Forces Hospital, Riyadh, Saudi Arabia. Results: Only 28% were aware of the sources of vitamin D, while 64% of healthy subjects were aware. Similarly, only 50% of patients …


Epidemiological Aspects Of Prematurity In The Eastern Region Of Saudi Arabia, Faisal O. Al-Qurashi, Abdullah A. Yousef, Bassam H. Awary Apr 2016

Epidemiological Aspects Of Prematurity In The Eastern Region Of Saudi Arabia, Faisal O. Al-Qurashi, Abdullah A. Yousef, Bassam H. Awary

Saudi Medical Journal

Objectives: To assess the epidemiological characteristics of prematurity and survival rate in preterm infants diagnosed at a university hospital in the Eastern province of Saudi Arabia. Methods: A retrospective study was carried out of 476 preterm infants who were admitted with the diagnosis of prematurity to King Fahd Hospital of the University, Al-Khobar, Saudi Arabia, between June 2008 and 2013. Demographics, birth weight, and neonatal survival rate were analyzed. Results: Four hundred and seventy-six preterm infants were admitted with a total prevalence of 7.5%. Descriptive analysis revealed 55% were males. Extremely preterm infants (<28 weeks’ gestation) comprised 9% and very preterm infants (28 to <32 weeks’ gestation) comprised 20%. Extremely low-birth-weight (ELBW) infants (<1000 g) comprised 11%. One hundred and fifty-seven (32%) infants were small for gestational age. Out of the total number of ELBW infants, 58% of them were discharged. The overall mortality was 7.6%. The mortality rate of male infants was 53%. The survival to discharge according to gestational age ranged from 30-97.6%. Conclusion: The estimated prevalence of preterm births in a university hospital in eastern province of Saudi Arabia, is consistent with various studies from different parts of the world.


The Association Between Body Mass Index And Duration Spent On Electronic Devices In Children And Adolescents In Western Saudi Arabia, Abdulmoein E. Al-Agha, F. Sarah Nizar, Anwar M. Nahhas Apr 2016

The Association Between Body Mass Index And Duration Spent On Electronic Devices In Children And Adolescents In Western Saudi Arabia, Abdulmoein E. Al-Agha, F. Sarah Nizar, Anwar M. Nahhas

Saudi Medical Journal

Objectives: To evaluate the relationship between body mass index (BMI) and the duration spent on electronic devices, and to assess the factors that can cause obesity among children. Methods: A cross-sectional study including 541 participants. Data was collected from March to June 2015 via ambulatory pediatric clinics in Jeddah, Kingdom of Saudi Arabia. The BMI standard deviation was calculated based on Center of Disease Control and Prevention (CDC) standards. Results: The mean age of the participants was 10.1 years. Children who spent ≥2 hours daily on electronic devices showed an increased BMI, and made up 68.4% of the sample. Conclusion: …


Pattern Of Thyroid, Celiac, And Anti-Cyclic Citrullinated Peptide Autoantibodies Coexistence With Type 1 Diabetes Mellitus In Patients From Southwestern Saudi Arabia, Ahmed M. Al-Hakami Apr 2016

Pattern Of Thyroid, Celiac, And Anti-Cyclic Citrullinated Peptide Autoantibodies Coexistence With Type 1 Diabetes Mellitus In Patients From Southwestern Saudi Arabia, Ahmed M. Al-Hakami

Saudi Medical Journal

Objectives: To investigate the seroprevalence of coexisting autoantibodies among type 1 diabetes mellitus (T1DM) patients, and to look for possible correlations with age at diagnosis, diabetes duration, and glycemic control. Methods: This is a cross-sectional study conducted at Aseer Central Hospital, Abha, Kingdom of Saudi Arabia from March 2013 to June 2014. A total of 202 T1DM patients were screened for serum anti-thyroglobulin (TG), anti-thyroid peroxidase (TPO), anti-tissue transglutaminase (aTTG), anti-endomysial (EMA), and anti-cyclic citrullinated peptide (anti-CCP) antibodies along with glycated hemoglobin, and biometric data. Results: From the 202 T1DM patients (96 males, and 106 females) (mean age: 11.3 years), …


Prevalence And Risk Factors Of Early Fecal Carriage Of Enterococcus Faecalis And Staphylococcus Spp And Their Antimicrobial Resistant Patterns Among Healthy Neonates Born In A Hospital Setting In Central Saudi Arabia, Talat A. El-Kersh, Mohammed A. Marie, Yazeed A. Al-Sheikh, Mohamed H. Al-Agamy, Ahmad A. Al-Bloushy Mar 2016

Prevalence And Risk Factors Of Early Fecal Carriage Of Enterococcus Faecalis And Staphylococcus Spp And Their Antimicrobial Resistant Patterns Among Healthy Neonates Born In A Hospital Setting In Central Saudi Arabia, Talat A. El-Kersh, Mohammed A. Marie, Yazeed A. Al-Sheikh, Mohamed H. Al-Agamy, Ahmad A. Al-Bloushy

Saudi Medical Journal

Objectives: To investigate the prevalence, antibiotic resistant profiles, and risk factors of early fecal carriage of Enterococcus faecalis (E. faecalis) and staphylococci among 150 healthy Saudi neonates born in a hospital setting in central Saudi Arabia. Methods: This prospective study was conducted in Al-Bukayriyah General Hospital, Qassim, Saudi Arabia, between June 2012 and January 2013. The E. faecalis and Staphylococcus spp. isolates were identified manually, and Vitek2 system was used for identity confirmation at the species level and minimum inhibitory concentration-susceptibility testing. Results: Enterococcus faecalis (n=73) and Staphylococcus spp. (n=18) were recovered. Unlike staphylococci, E. faecalis colonization did not significantly …


Nigella Sativa And Its Active Constituent Thymoquinone In Oral Health, Safia A. Alattas, Fat’Heya M. Zahran, Shereen A. Turkistany Mar 2016

Nigella Sativa And Its Active Constituent Thymoquinone In Oral Health, Safia A. Alattas, Fat’Heya M. Zahran, Shereen A. Turkistany

Saudi Medical Journal

In this review, we summarized published reports that investigated the role of Nigella sativa (NS) and its active constituent, thymoquinone (TQ) in oral health and disease management. The literature studies were preliminary and scanty, but the results revealed that black seed plants have a potential therapeutic effect for oral and dental diseases. Such results are encouraging for the incorporation of these plants in dental therapeutics and hygiene products. However, further detailed preclinical and clinical studies at the cellular and molecular levels are required to investigate the mechanisms of action of NS and its constituents, particularly TQ.


Diagnostic Efficacy Of Random Albumin Creatinine Ratio For Detection Of Micro And Macro-Albuminuria In Type 2 Diabetes Mellitus, Rana M. Hasanato Mar 2016

Diagnostic Efficacy Of Random Albumin Creatinine Ratio For Detection Of Micro And Macro-Albuminuria In Type 2 Diabetes Mellitus, Rana M. Hasanato

Saudi Medical Journal

Objectives: To compare a less cumbersome random albumin creatinine ratio (RACR) with 24-hour urinary albumin excretion (UAE) for detection of renal damage in patients with type 2 diabetes mellitus (T2DM). Methods: This retrospective study performed between March 2013 and June 2014 at the Department of Pathology, King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia included 122 patients (mean age 54±15, 104 females and 18 males) with T2DM. Urine albumin levels of <30 mg/g was considered normal, from 30-300 mg/g considered as micro-albuminuria, and over 300 mg/g considered as macro-albuminuria. Results: Concordance between the 2 assays was observed in 114 (93.4%) samples. The sensitivity of RACR assay was 100%, specificity was 91.3% with a positive predictive value (PPV) of 95%, and a negative predictive value (NPV) of 100% in micro-albuminuria range. For macro-albuminuria, RACR had a sensitivity of 100%, specificity of 94.1% with PPV of 94% and NPV of 100%. Receiver operating characteristic (ROC) curves analysis cut-off values of 40 mg/g-300 mg/g for micro- and >300 mg/g for macro-albuminuria revealed 100% sensitivity, 97.5% specificity, 95% PPV, and 100% NPV for micro-albuminuria, and 100% sensitivity, 94% specificity, 76% PPV, and 100% NPP for macro-albuminuria. …


Growth Assessment And Risk Factors Of Malnutrition In Children With Cystic Fibrosis, Hasan M. Isa, Lina F. Al-Ali, Afaf M. Mohamed Mar 2016

Growth Assessment And Risk Factors Of Malnutrition In Children With Cystic Fibrosis, Hasan M. Isa, Lina F. Al-Ali, Afaf M. Mohamed

Saudi Medical Journal

Objectives: To evaluate the nutritional status, to screen for the presence of malnutrition, and to study the possible risk factors associated with malnutrition in patients with cystic fibrosis (CF). Methods: A retrospective cross-sectional review of medical records of all diagnosed CF patients in the Pediatric Department, Salmaniya Medical Complex, Manama, Kingdom of Bahrain, between January 1984 and May 2015 was conducted. Demographic and anthropometric data were collected from records of last visit to CF clinic. Nutritional status and risk factors of malnutrition were assessed. Results: All records of 109 CF patients were reviewed. Forty-seven pediatric patients were included in the …


Stress, Shift Duty, And Eating Behavior Among Nurses In Central Saudi Arabia, Ali M. Almajwal Feb 2016

Stress, Shift Duty, And Eating Behavior Among Nurses In Central Saudi Arabia, Ali M. Almajwal

Saudi Medical Journal

Objectives: To investigate the association between stress, shift work, and eating behavior among non-Saudi female nurses working in Central Saudi Arabia. Methods: A sample of 395 non-Saudi female nurses from 2 major hospitals in Riyadh, Kingdom of Saudi Arabia participated in this cross-sectional study. The nurses completed a questionnaire from November 2013 to January 2014 that included items relating to stress and eating behavior using the Dutch Eating Behavior Questionnaire (DEBQ). The questionnaire also contained items pertaining to socio-demographic data, body mass index, shift work, and hours worked per week. Results: For all eating styles, stress, and shift duty influenced …


Correlation Between Obesity And Emotional, Social, And Behavioral Problems Associated With Physical Limitation Among Children And Adolescents In Western Saudi Arabia, Abdulmoein E. Al-Agha, Rahma A. Al-Ghamdi, Shaimaa A. Halabi Feb 2016

Correlation Between Obesity And Emotional, Social, And Behavioral Problems Associated With Physical Limitation Among Children And Adolescents In Western Saudi Arabia, Abdulmoein E. Al-Agha, Rahma A. Al-Ghamdi, Shaimaa A. Halabi

Saudi Medical Journal

Objectives: To evaluate the impact of body mass index (BMI) on limitation of physical activity and the associated effect on behavioral, school, and social problems among obese children in Western Saudi Arabia. Methods: A cross-sectional obesity survey was conducted in Jeddah, Saudi Arabia. Data were collected between August 2014 and February 2015 from 281 obese children aged between 2-18 (girls: 130, boys: 151). Participants were selected randomly to represent different economic status, level of education, and family structure. Results: The mean age of participants was 10.5 years for girls and 10.6 years for boys. Higher BMI was associated with physical …


Intestinal Lymphangiectasia In Children: A Favorable Response To Dietary Modifications, Hasan M. Isa, Ghadeer G. Al-Arayedh, Afaf M. Mohamed Feb 2016

Intestinal Lymphangiectasia In Children: A Favorable Response To Dietary Modifications, Hasan M. Isa, Ghadeer G. Al-Arayedh, Afaf M. Mohamed

Saudi Medical Journal

Intestinal lymphangiectasia (IL) is a rare disease characterized by dilatation of intestinal lymphatics. It can be classified as primary or secondary according to the underlying etiology. The clinical presentations of IL are pitting edema, chylous ascites, pleural effusion, acute appendicitis, diarrhea, lymphocytopenia, malabsorption, and intestinal obstruction. The diagnosis is made by intestinal endoscopy and biopsies. Dietary modification is the mainstay in the management of IL with a variable response. Here we report 2 patients with IL in Bahrain who showed positive response to dietary modification.


Comparison Of The Effect Of Rocuronium Dosing Based On Corrected Or Lean Body Weight On Rapid Sequence Induction And Neuromuscular Blockade Duration In Obese Female Patients, Bahar Sakızcı-Uyar, Şeref Çelik, Aysun Postacı, Yeşim Bayraktar, Bayazit Dikmen, Işıl Özkoçak-Turan, Özlem Saçan Jan 2016

Comparison Of The Effect Of Rocuronium Dosing Based On Corrected Or Lean Body Weight On Rapid Sequence Induction And Neuromuscular Blockade Duration In Obese Female Patients, Bahar Sakızcı-Uyar, Şeref Çelik, Aysun Postacı, Yeşim Bayraktar, Bayazit Dikmen, Işıl Özkoçak-Turan, Özlem Saçan

Saudi Medical Journal

Objectives: To compare onset time, duration of action, and tracheal intubation conditions in obese patients when the intubation dose of rocuronium was based on corrected body weight (CBW) versus lean body weight (LBW) for rapid sequence induction. Methods: This prospective study was carried out at Numune Education and Research Hospital, Ankara, Turkey between August 2013 and May 2014. Forty female obese patients scheduled for laparoscopic surgery under general anesthesia were randomized into 2 groups. Group CBW (n=20) received 1.2 mg/kg rocuronium based on CBW, and group LBW (n=20) received 1.2 mg/kg rocuronium based on LBW. Endotracheal intubation was performed 60 …


Will The Eastern Mediterranean Region Be The First To Prevent All Of Folic Acid-Preventable Spina Bifida And Anencephaly?, Godfrey P. Oakley, Vijaya Kancherla Jan 2016

Will The Eastern Mediterranean Region Be The First To Prevent All Of Folic Acid-Preventable Spina Bifida And Anencephaly?, Godfrey P. Oakley, Vijaya Kancherla

Saudi Medical Journal

No abstract provided.


Assessment Of The Environmental And Genetic Factors Influencing Prevalence Of Metabolic Syndrome In Saudi Arabia, Ibrahim M. Gosadi Jan 2016

Assessment Of The Environmental And Genetic Factors Influencing Prevalence Of Metabolic Syndrome In Saudi Arabia, Ibrahim M. Gosadi

Saudi Medical Journal

Metabolic syndrome (MS) is a combination of factors that increases the risk of cardiovascular atherosclerotic diseases including diabetes, obesity, dyslipidemia, and high blood pressure. Cardiovascular diseases are one of the leading causes of death in the adult Saudi population where the increase in cardiovascular-related mortality is augmented by the rise in the prevalence of MS. Metabolic syndrome is a multi-factorial disorder influenced by interactions between genetic and environmental components. This review aims to provide a comprehensive assessment of studied environmental and genetic factors explaining the prevalence of MS in the Kingdom of Saudi Arabia. Additionally, this review aims to illustrate …


Low Oxytocin And Melatonin Levels And Their Possible Role In The Diagnosis And Prognosis In Iraqi Autistic Children, Haidar A. Abdulamir, Omar F. Abdul-Rasheed, Emad A. Abdulghani Jan 2016

Low Oxytocin And Melatonin Levels And Their Possible Role In The Diagnosis And Prognosis In Iraqi Autistic Children, Haidar A. Abdulamir, Omar F. Abdul-Rasheed, Emad A. Abdulghani

Saudi Medical Journal

Objectives: To test the possible association between oxytocin and melatonin levels with the severity of social and cognitive dysfunctions, and to study the correlation between these parameters in children with autism. Methods: A case-control study was carried out in the Department of Chemistry and Biochemistry, College of Medicine, Al-Nahrain University, Baghdad, Iraq. The study was performed on 60 male autistic patients recruited from the Pediatric Department of Al-Sader General Hospital, Baghdad, Iraq between November 2014 and April 2015. The levels of oxytocin and melatonin were measured in the serum of these autistic male patients, and categorized as mild, moderate, and …


Evaluation Of Health Care Services Provided For Older Adults In Primary Health Care Centers And Its Internal Environments, Hakan Yaman Jan 2016

Evaluation Of Health Care Services Provided For Older Adults In Primary Health Care Centers And Its Internal Environments, Hakan Yaman

Saudi Medical Journal

No abstract provided.


Effects Of 12-Month, 2000iu/Day Vitamin D Supplementation On Treatment Naïve And Vitamin D Deficient Saudi Type 2 Diabetic Patients, Abdulaziz M. Al-Othman, Nasser M. Al-Daghri, Shaun B. Sabico Dec 2015

Effects Of 12-Month, 2000iu/Day Vitamin D Supplementation On Treatment Naïve And Vitamin D Deficient Saudi Type 2 Diabetic Patients, Abdulaziz M. Al-Othman, Nasser M. Al-Daghri, Shaun B. Sabico

Saudi Medical Journal

Objectives: To determine whether 12-month, 2000IU/day vitamin D supplementation cardiometabolically improves treatment naïve type 2 diabetes mellitus (T2DM) Saudi patients with vitamin D deficiency. Methods: This 12-month interventional study was conducted at primary health centers in 5 different residential areas in Riyadh, Saudi Arabia between January 2013 and January 2014. Forty-five Saudi T2DM patients were enrolled. Baseline anthropometrics, glycemic, and lipid profiles were measured and repeated after 6 and 12 months. All subjects were provided with 2000IU vitamin D supplements for one year. Results: Vitamin D deficiency at baseline was 46.7%, 31.8% after 6 months, and 35.6% after 12 months, …


Lack Of Association Between The Insulin Receptor Substrates-1 Gly972arg Polymorphism And Type-2 Diabetes Mellitus Among Saudis From Eastern Saudi Arabia, Hawra A. Alsalman, Yahia A. Kaabi Dec 2015

Lack Of Association Between The Insulin Receptor Substrates-1 Gly972arg Polymorphism And Type-2 Diabetes Mellitus Among Saudis From Eastern Saudi Arabia, Hawra A. Alsalman, Yahia A. Kaabi

Saudi Medical Journal

Objectives: To investigate the association between the insulin receptor substrate-1 ( IRS1 ) Gly972Arg polymorphism and type-2 diabetes mellitus (T2DM) among Saudis from Eastern Saudi Arabia. Methods: This study was conducted between May and December 2014 at King Fahad Hospital of the University, Al-Khobar, Kingdom of Saudi Arabia. In a case-control study design, a total of 143 subjects (age range: 35-73 years) comprising 74 healthy controls and 69 patients with T2DM were examined. Blood samples were collected from subjects and subjected to genomic DNA extraction and chemical analysis. The IRS1 Gly972Arg polymorphism was then genotyped using the standard polymerase chain …