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Scalp Roof Tiles.: A New Diagnostic Sign In Neonates With Netherton Syndrome, Sultan Al-Khenaizan, Luluah Al-Mubarak Apr 2021

Scalp Roof Tiles.: A New Diagnostic Sign In Neonates With Netherton Syndrome, Sultan Al-Khenaizan, Luluah Al-Mubarak

Saudi Medical Journal

Clinical Presentation A 2-month-old baby boy, of full-term spontaneous vaginal delivery, presented to the dermatology outpatient clinic with generalized erythroderma, which had been noted since birth. Family history was positive for similar disease in his eldest sister, who died at 6 months of age without a diagnosis. On examination, the patient looked ill with generalized erythroderma, yet there were no signs of ectropion, eclabium, or deformed ears. Diffuse scalp scaling was observed with interlocking tessellation scales over the scalp (Figure 1). Hair microscopy showed in Figure 2. All laboratory results were normal.


Comment On: Safety And Cost-Effectiveness Of Outpatient Thyroidectomy: A Retrospective Observational Study, Sandro Contini, Samiah S. Alangari Apr 2021

Comment On: Safety And Cost-Effectiveness Of Outpatient Thyroidectomy: A Retrospective Observational Study, Sandro Contini, Samiah S. Alangari

Saudi Medical Journal

No abstract provided.


Cochrane Review Finds Stopping Smoking Is Linked To Improved Mental Health Apr 2021

Cochrane Review Finds Stopping Smoking Is Linked To Improved Mental Health

Saudi Medical Journal

No abstract provided.


New Research Highlights Risks Of Separating Newborns From Mothers During Covid-19 Pandemic. Keeping Mothers And Babies Together Could Save More Than 125 000 Lives: Who Apr 2021

New Research Highlights Risks Of Separating Newborns From Mothers During Covid-19 Pandemic. Keeping Mothers And Babies Together Could Save More Than 125 000 Lives: Who

Saudi Medical Journal

No abstract provided.


Instructions To Authors Apr 2021

Instructions To Authors

Saudi Medical Journal

No abstract provided.


Effects Of Chronic Pain On Sleep Quality And Depression: A Cross-Sectional Study, Eman A. Alhalal, Ibrahim A. Alhalal, Amani M. Alaida, Sabreen M. Alhweity, Asma Y. Alshojaa, Amani T. Alfaori Mar 2021

Effects Of Chronic Pain On Sleep Quality And Depression: A Cross-Sectional Study, Eman A. Alhalal, Ibrahim A. Alhalal, Amani M. Alaida, Sabreen M. Alhweity, Asma Y. Alshojaa, Amani T. Alfaori

Saudi Medical Journal

Objectives: To examined the impacts of chronic pain on depression and poor sleep quality dimensions as well as the mediating function of poor sleep quality in the pathway between chronic pain and depression. Methods: Between March 2019 and February 2020, we conducted a cross-sectional study on 233 chronic pain patients in 2 tertiary hospitals in Riyadh, Saudi Arabia. Results: Of the 233 patients, 36% had depression, while 66.1% had poor sleep quality. Chronic pain intensity and pain disability significantly explained 10.9% of depressed affect variance, 4.9% of anhedonia variance, 17.3% of somatic complaint variance, 4.5% of interpersonal difficulty variance, 7.4% …


Prediction Of Squamous Cell Carcinoma Cases From Squamous Cell Hyperplasia In Throat Lesions Using Ct Radiomics Model, Osama A. Khodrog, Fengzhi Cui, Nannan Xu, Qinghe Han, Jianhua Liu, Tingting Gong, Qinghai Yuan Mar 2021

Prediction Of Squamous Cell Carcinoma Cases From Squamous Cell Hyperplasia In Throat Lesions Using Ct Radiomics Model, Osama A. Khodrog, Fengzhi Cui, Nannan Xu, Qinghe Han, Jianhua Liu, Tingting Gong, Qinghai Yuan

Saudi Medical Journal

Objectives: To differentiate squamous cell hyperplasia (SCH) (benign) from squamous cell carcinoma (SCC) malignant) using textural features extracted from CT images and thereby, facilitate the preoperative medical diagnosis and treatment of throat cancers without the need for sample biopsies. Methods: In total, 100 throat cancer patients were selected for this retrospective study. The cases were collected from the Second Hospital of Jilin University, Changchun, China, from June 2017 to January 2019. The patients were separated into a training and validation cohort consisting of 70 and 30 cases, respectively. The Artificial Intelligence Kit software (A.K. software) was used to extract the …


Insulinoma In Tuberous Sclerosis: An Entity Not To Be Missed, Shoukat A. Bojal, Abdullah A. Alqarzaie, Abdulaziz A. Alqahtani Mar 2021

Insulinoma In Tuberous Sclerosis: An Entity Not To Be Missed, Shoukat A. Bojal, Abdullah A. Alqarzaie, Abdulaziz A. Alqahtani

Saudi Medical Journal

Pancreatic neuroendocrine tumors are rare with an incident rate of 5 cases per million individuals. Tuberous sclerosis complex is an autosomal dominant disease. This disease involves multisystem and occurs in one out of every 6,000-10,000 individuals. In this study, we describe a 47-year-old male known tuberous sclerosis patient with an insulinoma. The tumor was incidentally detected in follow-up imaging for a previous ampulla of Vater tubular adenoma. However, the patient reported symptoms of hypoglycemia. The insulinoma was enucleated successfully. Histopathology revealed a well-differentiated, grade one neuroendocrine tumor measuring around 2 cm in diameter. Seven cases were reported in the literature …


Physical Conditions Linked To Psychological Distress In Patients With Cancer Mar 2021

Physical Conditions Linked To Psychological Distress In Patients With Cancer

Saudi Medical Journal

No abstract provided.


In This Issuereview Articleoriginal Articlescase Report Mar 2021

In This Issuereview Articleoriginal Articlescase Report

Saudi Medical Journal

No abstract provided.


The Effect Of Low Flow Anesthesia On Hemodynamic And Peripheral Oxygenation Parameters In Obesity Surgery, Mesut Öterkuş, İlksen Dönmez, Aysu H. Nadir, İbrahim Rencüzoğulları, Yavuz Karabağ, Kenan Binnetoğlu Mar 2021

The Effect Of Low Flow Anesthesia On Hemodynamic And Peripheral Oxygenation Parameters In Obesity Surgery, Mesut Öterkuş, İlksen Dönmez, Aysu H. Nadir, İbrahim Rencüzoğulları, Yavuz Karabağ, Kenan Binnetoğlu

Saudi Medical Journal

Objectives: To investigate the effects of low-flow anesthesia on hemodynamic parameters and recovery from anesthesia in obese individuals undergoing laparoscopic surgery. Methods: This randomized-controlled and prospective study included 44 obese patients who underwent laparoscopic sleeve gastrectomy operation. The patients were randomly allocated into 2 groups as low-flow and high-flow anesthesia. Further, the groups compared in terms of hemodynamic parameters, anesthesia recovery times, operation times, and arterial blood gas parameters. Results: The groups were similar with respect to demographic data. Heart rate, peripheral oxygen saturation, arterial blood pressure measurements, end-tidal, and CO 2 , lactate levels measurements were similar in both …


Pathological Spectrum Of Endometrial Biopsies In Saudi Women With Abnormal Uterine Bleeding: A Retrospective Study Of 13-Years, Sufia Husain, Aljawhara K. Alduhaysh, Mada M. Albatly, Ammar Alrikabi Mar 2021

Pathological Spectrum Of Endometrial Biopsies In Saudi Women With Abnormal Uterine Bleeding: A Retrospective Study Of 13-Years, Sufia Husain, Aljawhara K. Alduhaysh, Mada M. Albatly, Ammar Alrikabi

Saudi Medical Journal

Objectives: To assess and age stratify the types and frequencies of endometrial pathologies in Saudi women with abnormal uterine bleeding (AUB) that underwent endometrial biopsies, at our hospital over a 13-year period. Methods: In a retrospective study, from 2006 to 2018, all endometrial biopsies from Saudi women with AUB, reported at the laboratory of King Saud University-Medical City, Riyadh, Saudi Arabia, were revisited and analyzed. The women were categorized into <40, between 40-55 and >55 years of age. Results: We analyzed 6458 biopsies. In <40 and 40-55 years’ groups cyclical endometrium was most common followed by endometrial polyps and disordered proliferative endometrium. In the >55 years’ group, atrophic endometrium was most common followed by endometrial polyps. The hyperplasias and malignancies together accounted for 7.2% …


Patterns Of Pediatric Thoracic Penetrating Injuries: A Single-Trauma-Center Experience In Riyadh, Saudi Arabia, Suliaman M. Alaqeel, Abdulaziz A. Howsawi Mar 2021

Patterns Of Pediatric Thoracic Penetrating Injuries: A Single-Trauma-Center Experience In Riyadh, Saudi Arabia, Suliaman M. Alaqeel, Abdulaziz A. Howsawi

Saudi Medical Journal

Objectives: To review the patterns and outcomes of pediatric thoracic penetrating injuries in a level one trauma center. Methods: Retrospective chart review of pediatric patients who presented to the King Abdulaziz Medical City Emergency Department (KAMC-ED), Riyadh, Saudi Arabia with thoracic penetrating injury from 2001 to 2016. Results: Eighty-nine patients had a penetrating injury to the thorax were identified. The mean age was 15.5 ± 3.6 years. The mean length of hospital stay was 3.87 ± 5 days. The most common cause was stabbing followed by gunshot. Isolated injury to the thorax was seen in 58 patients. The most common …


Correlation Of Prognostic And Predictive Indicators In Breast Cancer Patients From The Eastern Province Of Saudi Arabia, Haitham A. Kussaibi Mar 2021

Correlation Of Prognostic And Predictive Indicators In Breast Cancer Patients From The Eastern Province Of Saudi Arabia, Haitham A. Kussaibi

Saudi Medical Journal

Objectives: To highlight and correlate demographic and histopathological features of breast cancer along with prognostic and predictive biomarkers, in Saudi patients from the Eastern Province and compare it to a cohort of non-Saudi patients. Methods: In a retrospective study between January 1998 and December 2017, data were collected from the medical records of breast cancer patients who were admitted at King Fahd University Hospital (KFHU), Dammam, Saudi Arabia. The information included demographic, histopathological, and immunohistochemical findings. Results: Out of 482 breast cancer patients, 60% (n=286) were Saudis, and 40% (n=196) were non-Saudis. Data showed a wide age distribution; however, most …


Covid-19 In Children Ranging From Asymptomatic To A Multi-System Inflammatory Disease: A Single-Center Study, Walaa Shahin, Walaa Rabie, Osama Alyossof, Mohammed Alasiri, Mohamed Alfaki, Elamin Mahmoud, Muwaffak Hijazi, Huda El Faraidi, Hassan Alahmari Mar 2021

Covid-19 In Children Ranging From Asymptomatic To A Multi-System Inflammatory Disease: A Single-Center Study, Walaa Shahin, Walaa Rabie, Osama Alyossof, Mohammed Alasiri, Mohamed Alfaki, Elamin Mahmoud, Muwaffak Hijazi, Huda El Faraidi, Hassan Alahmari

Saudi Medical Journal

Objectives: To identify clinical and laboratory characteristics of the Saudi children with confirmed COVID-19. Methods: Eighty-eight children (0-14 years) with COVID-19 who were admitted to Prince Sultan Military Medical City (PSMMC), Riyadh, Saudi Arabia from April to June 2020 were recruited. Results: Mean age was 5.74 ± 4.7 years with 41 (49.4%) males and 42 (50.6%) females. The length of hospital stay (LOS) ranged from 1 to 17 days. The main source of infection was infected family members. Mean values of C-reactive protein (CRP), serum ferritin, and lactate dehydrogenase (LDH) were noticeably above normal. Degree of severity and length of …


Health Care Worker Burnout During The Covid-19 Pandemic: A Cross-Sectional Survey Study In Saudi Arabia, Loui K. Alsulimani, Abdulrahman M. Farhat, Renad A. Borah, Jumanah A. Alkhalifah, Salman M. Alyaseen, Sumaeah M. Alghamdi, Malak J. Bajnaid Mar 2021

Health Care Worker Burnout During The Covid-19 Pandemic: A Cross-Sectional Survey Study In Saudi Arabia, Loui K. Alsulimani, Abdulrahman M. Farhat, Renad A. Borah, Jumanah A. Alkhalifah, Salman M. Alyaseen, Sumaeah M. Alghamdi, Malak J. Bajnaid

Saudi Medical Journal

Objectives: To estimate the prevalence of burnout among health care workers (HCWs) who are working in Saudi Arabia during the Coronavirus disease 2019 (COVID-19) pandemic, and explore individual and work-related factors associated with burnout in this population. Methods: In this cross-sectional study conducted between June to August of 2020, we invited HCWs through social channels to complete a questionnaire. The questionnaire inquired about demographics, factors related to burnout, and used the Copenhagen Burnout Inventory scale to indicate burnout. A total of 646 HCWs participated. Results: The mean (SD) age of participants was 34.1 (9.5) years. Sixty-one percent were female. The …


A Comparative Study Of Online Learning In Response To The Coronavirus Disease 2019 Pandemic Versus Conventional Learning, Safaa M. Hanafy, Mohammad I. Jumaa, Mostafa A. Arafa Mar 2021

A Comparative Study Of Online Learning In Response To The Coronavirus Disease 2019 Pandemic Versus Conventional Learning, Safaa M. Hanafy, Mohammad I. Jumaa, Mostafa A. Arafa

Saudi Medical Journal

Objectives: To explore the attitude and perception of undergraduate medical students and their staff towards the educational methods (conventional versus online) and to assess their performance accordingly. Methods: It was a comparative cross sectional study, conducted at the Faculty of Medicine, Al- Imam University, Riyadh, Saudi Arabia on May 30, 2020. A structured questionnaire was designed to collect the data from students and staff about conventional teaching, online teaching, conventional examination and online examination. It was in the form of 5-point Likert-type scale ranging from 5-strongly agree, to 1-strongly disagree, in addition to age and gender. The results of conventional …


Epidemiological Characteristics Of Cervical Cancer In A Tertiary Care Hospital, Western Saudi Arabia: A Retrospective Record-Based Analysis From 2002-2018, Fayssal M. Farahat, Norah T. Faqih, Razan S. Alharbi, Raheed I. Mudarris, Sahl A. Alshaikh, Hatim M. Al-Jifree Mar 2021

Epidemiological Characteristics Of Cervical Cancer In A Tertiary Care Hospital, Western Saudi Arabia: A Retrospective Record-Based Analysis From 2002-2018, Fayssal M. Farahat, Norah T. Faqih, Razan S. Alharbi, Raheed I. Mudarris, Sahl A. Alshaikh, Hatim M. Al-Jifree

Saudi Medical Journal

Objectives: To investigate the epidemiological characteristics of cervical cancer cases reported at a tertiary care teaching hospital in western Saudi Arabia. Methods: A retrospective chart review was conducted on medical records of patients diagnosed with cervical cancer at King Abdulaziz Medical City, Jeddah, Saudi Arabia. Data were collected on demographic characteristics, histological types and stage, treatment modalities, and disease outcomes. Results: Cervical cancer was diagnosed among 89 patients from 2002 to 2018. History of pap smear was reported among 31 cases (34.8%). Squamous cell carcinoma was the most common reported histopathological subtype. Almost one third (29.2%) of the patients were …


Is Chloroquine Or Hydroxychloroquine Useful In Treating People With Covid-19, Or In Preventing Infection In People Who Have Been Exposed To The Virus? Mar 2021

Is Chloroquine Or Hydroxychloroquine Useful In Treating People With Covid-19, Or In Preventing Infection In People Who Have Been Exposed To The Virus?

Saudi Medical Journal

No abstract provided.


Covax Statement On Who Emergency Use Listing For Astrazeneca/Oxford Covid-19 Vaccine Mar 2021

Covax Statement On Who Emergency Use Listing For Astrazeneca/Oxford Covid-19 Vaccine

Saudi Medical Journal

No abstract provided.


Who Launches New Tools To Help Countries Build Effective Childhood Cancer Programmes Mar 2021

Who Launches New Tools To Help Countries Build Effective Childhood Cancer Programmes

Saudi Medical Journal

No abstract provided.


In This Issueclinical Guidelinesoriginal Articlescase Report Feb 2021

In This Issueclinical Guidelinesoriginal Articlescase Report

Saudi Medical Journal

No abstract provided.


Comment On: Patterns Of Cervical Spine Injuries In Adults At A Major Trauma Center In Saudi Arabia, Abdulrahman Albahkley, Rouaa Mandurah, Ahoud Alharbi Feb 2021

Comment On: Patterns Of Cervical Spine Injuries In Adults At A Major Trauma Center In Saudi Arabia, Abdulrahman Albahkley, Rouaa Mandurah, Ahoud Alharbi

Saudi Medical Journal

No abstract provided.


Caffeine Modulates Pharmacokinetic And Pharmacodynamic Profiles Of Pioglitazone In Diabetic Rats: Impact On Therapeutics, Ali M. Alshabi, Saad A. Alkahtani, Ibrahim A. Shaikh, Mohammed S. Habeeb Feb 2021

Caffeine Modulates Pharmacokinetic And Pharmacodynamic Profiles Of Pioglitazone In Diabetic Rats: Impact On Therapeutics, Ali M. Alshabi, Saad A. Alkahtani, Ibrahim A. Shaikh, Mohammed S. Habeeb

Saudi Medical Journal

Objectives: To determine the influence of caffeine on pharmacokinetics and pharmacodynamics of pioglitazone (PIO) in diabetic rats. Methods: This was a preclinical study conducted in the College of Pharmacy, Najran University, Saudi Arabia, using 5 groups of Wistar rats: normal rats, untreated diabetic rats, diabetic rats + caffeine (20 mg/kg), diabetic rats + PIO (10 mg/kg), and diabetic rats + PIO (10 mg/kg) + caffeine (20 mg/kg). The drugs were administered for 14 days, and fasting plasma glucose concentrations were determined on the first day, and thereafter at weekly intervals. On day 14, rat sacrifice was followed with assay of …


Diabetes Mellitus As A Comorbidity In Covid-19 Infection In The United Arab Emirates, Noha M. Elemam, Haifa Hannawi, Issa Al Salmi, Kashif Bin Naeem, Fahdah Alokaily, Suad Hannawi Feb 2021

Diabetes Mellitus As A Comorbidity In Covid-19 Infection In The United Arab Emirates, Noha M. Elemam, Haifa Hannawi, Issa Al Salmi, Kashif Bin Naeem, Fahdah Alokaily, Suad Hannawi

Saudi Medical Journal

Objectives: To compare risk factors and clinical outcomes among COVID-19 patients with or without diabetes in the United Arab Emirates (UAE). Methods: Data of 350 COVID-19 positive patients, admitted to Al Kuwait Hospital in Dubai, UAE, from February to May 2020 was collected retrospectively, including demographic data, clinical symptoms, blood tests, as well as radiographical assessments, and clinical outcomes of COVID-19. The design of the study is a retrospective cohort study. Results: COVID-19 patients with diabetes belong to an older age group, had a higher percentage of male patients, exhibited more lymphopenia and neutrophilia, and higher ferritin levels. Additionally, patients …


Saudi Arabia Guidelines For Diabetic Macular Edema: A Consensus Of The Saudi Retina Group, Abdullah S. Alqahtani, Mohammad A. Hazzazi, Saad A. Waheeb, Valmore A. Semidey, Valmore A. Semidey, Hussein K. Elgendy, Wajeeha I. Alkhars, Marwan A. Abouammoh, Hassan Al-Dhibi Feb 2021

Saudi Arabia Guidelines For Diabetic Macular Edema: A Consensus Of The Saudi Retina Group, Abdullah S. Alqahtani, Mohammad A. Hazzazi, Saad A. Waheeb, Valmore A. Semidey, Valmore A. Semidey, Hussein K. Elgendy, Wajeeha I. Alkhars, Marwan A. Abouammoh, Hassan Al-Dhibi

Saudi Medical Journal

ABSTRACT Diabetes mellitus (DM) and its complications are major public health burdens in Saudi Arabia. The prevalence of diabetic retinopathy (DR) is 19.7% and the prevalence of diabetic macular edema (DME) is 5.7% in Saudi Arabia. Diabetic macular edema is a vision-threatening complication of DR and a major cause of vision loss worldwide. Ocular treatments include retinal laser photocoagulation, anti-vascular endothelial growth factor (anti-VEGF) agents, intravitreal corticosteroids, and vitreoretinal surgery when necessary. The present consensus was developed as a part of the Saudi Retina Group’s efforts to generate Saudi guidelines and consensus for the management of DME, including recommendations for …


Microbiome: Role And Functionality In Human Nutrition Cycle, Fahad Alhusain Feb 2021

Microbiome: Role And Functionality In Human Nutrition Cycle, Fahad Alhusain

Saudi Medical Journal

ABSTRACT Microbes are present almost everywhere on this Earth. Humans harbor microbes in various organs, including skin, gut, mouth, and nose. Among these, the gut region has the highest population of microbes. Gut microbiota is directly linked with homeostasis, and a minor change in their numbers predisposes humans to ailments. Notably, the role of the microbial population in the digestive tract directly contributes to body weight. Sometimes, lifestyle changes or antibiotics intake to manage certain infections are associated with disturbance in the gut microflora. Several scientific studies allude to the obesity linkage with disturbed intestinal microflora. This review mainly focuses …


Vitamin B12 Deficiency In Patients With Type 2 Diabetes Mellitus Using Metformin And The Associated Factors In Saudi Arabia, Muneera A. Baraja Feb 2021

Vitamin B12 Deficiency In Patients With Type 2 Diabetes Mellitus Using Metformin And The Associated Factors In Saudi Arabia, Muneera A. Baraja

Saudi Medical Journal

Objectives: To assess the presence of vitamin B12 deficiency among metformin users and associated factors in patients with type 2 diabetes mellitus. Methods: An observational cross-sectional study was conducted with 307 diabetic patients in the primary health care centers at King Abdulaziz Medical City (KAMC), Riyadh, Saudi Arabia between October 2017 and January 2018. Face-to-face interviews were conducted with the participants, using a designed checklist. Results: The prevalence of vitamin B12 deficiency was (3.6%) and the majority of the sample had borderline B12 levels (66.1%). The vitamin B12 deficiency and borderline levels were strongly associated with the dose of metformin. …


Challenges In Diabetic Foot Treatment During Pandemic Of Covid-19, Haris Vukas, Dragan Piljic, Samra Kadić-Vukas, Dilista Piljic Feb 2021

Challenges In Diabetic Foot Treatment During Pandemic Of Covid-19, Haris Vukas, Dragan Piljic, Samra Kadić-Vukas, Dilista Piljic

Saudi Medical Journal

Objectives: To avoid hospital spread of Coronavirus-2019 (COVID-19) and to analyze out of hospital outcomes after amputation. Methods: Prospective analysis of data obtained from 60 diabetic patients in 2020 was performed at Cantonal Hospital Zenica, Zenica, Bosnia and Herzegovina. Personal protection equipment included double surgical mask, glasses, disposable surgical coats, and surgical masks for patients. Swabs were used to take samples from wounds. We randomly divided patients in 2 groups of 30 patients each. In pre-operative treatment, we used local anesthesia lidocaine hydrochloride 2% (Belupo, Koprivnica, Croatia) in group A and systemic analgesia intravenous tramadol chloride 100 mg intravenous (Krka, …


Sociodemographic And Clinical Predictors Of Refractory Type 2 Diabetes Patients: Findings From A Case-Control Study, Turki J. Alharbi, Ayla M. Tourkmani, Abdulaziz Bin Rsheed, Yasser K. Alotaibi Feb 2021

Sociodemographic And Clinical Predictors Of Refractory Type 2 Diabetes Patients: Findings From A Case-Control Study, Turki J. Alharbi, Ayla M. Tourkmani, Abdulaziz Bin Rsheed, Yasser K. Alotaibi

Saudi Medical Journal

Objectives: To identify the sociodemographic and clinical predictors of uncontrolled diabetic patients, to identify high-risk and people with impaired glycemic control, to establish more effective strategies for reducing morbidity and mortality. Methods: This case-control study of 8209 enrolled patients were included from the diabetes registry by Chronic Illness Center (CIC), Family and Community Medicin, Prince Sultan Military Medical City, Riyadh Saudi Arabia between February 2019 and February 2020. Cases are defined as patients with type II refractory diabetes having persistent HbA1c >9, not reach adequate glycemic control despite intensified therapy under specialist care (CIC) for at least 6 months. Controls …