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Identification Of Rpl5 Gene Variants And The Risk Of Hepatic Vein Thrombosis In Saudi Patients, Fathelrahman M. Hassan, Afnan A. Alsultan, Faisal Alzahrani, Waleed H. Albuali, Dalal K. Bubshait, Elfadil M. Abass, Mudathir A. Elbasheer, Abdulmohsen A. Alkhanbashi
Identification Of Rpl5 Gene Variants And The Risk Of Hepatic Vein Thrombosis In Saudi Patients, Fathelrahman M. Hassan, Afnan A. Alsultan, Faisal Alzahrani, Waleed H. Albuali, Dalal K. Bubshait, Elfadil M. Abass, Mudathir A. Elbasheer, Abdulmohsen A. Alkhanbashi
Saudi Medical Journal
Objectives: To identify ribosome protein L5 gene variants and the risk of hepatic vein thrombosis in Saudi patients. Methods: A case-control study was conducted during the period of May 2018 to September 2019. Sixty-five patient cases of hepatic vein thrombosis (HVT) were chosen, and 50 healthy individuals of the same ages and both gender were set as a control group. The genotype of the gene RPL5 was determined by PCR please provide abbreviation in full and capillary electrophoresis. Sanger sequencing for genetically screened variants was applied for the RPL5 gene. Results: Alleles A at variant rs182018447 and T allele at …
Factors Affecting Dimensions Of The Ethmoid Infundibulum And Maxillary Sinus Natural Ostium In A Normal Population, Mohammed A. Basurrah, Soo W. Kim
Factors Affecting Dimensions Of The Ethmoid Infundibulum And Maxillary Sinus Natural Ostium In A Normal Population, Mohammed A. Basurrah, Soo W. Kim
Saudi Medical Journal
Objectives: To investigate the ethmoid infundibulum (EI) and maxillary sinus natural ostium (MSNO) dimensions in normal sinuses of the Asian population; identified variation between sides, gender, and age groups; and to assess the effects of such variation on the measurements. Methods: We assessed EI dimension and MSNO diameter in computed tomography (CT) scans of the normal paranasal sinus of 100 patients who underwent trans-sphenoid endoscopic surgery. We compared demographic data and multiple anatomical variations. Results: The gap difference in EI length between the right and left sides significantly differed from 0 (0.47±1.38 mm). We found wider EI in people aged …
The Impact Of Emergency Antibiotic Administration Time On Patients With Sepsis, Saqer M. Althunayyan, Mohammed A. Aljanoubi, Sultan M. Alghadeer, Musab Z. Alharthi, Raied N. Alotaibi, Abdullah M. Mubarak, Abdulaziz M. Almutary
The Impact Of Emergency Antibiotic Administration Time On Patients With Sepsis, Saqer M. Althunayyan, Mohammed A. Aljanoubi, Sultan M. Alghadeer, Musab Z. Alharthi, Raied N. Alotaibi, Abdullah M. Mubarak, Abdulaziz M. Almutary
Saudi Medical Journal
Objectives: To assess the mortality benefits of timely antibiotic treatment of adults present at the emergency department with sepsis and compare one-hour administration and 3-hour administration starting from the time of triage. Methods: In this retrospective study, we used secondary data analysis to investigate the utility of the National Early Warning Score as a predictor of mortality in sepsis patients between July 2018 and June 2019, at the Emergency Department, King Saud Medical City, Riyadh, Saudi Arabia. The patients were grouped into 2 based on the time interval from triage to the first antibiotic administration: the immediate group received antibiotics …
The Outcome Of Prevention Of Mother-To-Child Transmission Of Hiv Infection At King Abdulaziz University Hospital, Western Region Of Saudi Arabia: A Descriptive Study, Elaf H. Ahmed, Mayar A. Shafei, Leena S. Alsubhi, Noora A. Zarban, Bashair A. Al-Zahrani, Mohammed Shaikhomer
The Outcome Of Prevention Of Mother-To-Child Transmission Of Hiv Infection At King Abdulaziz University Hospital, Western Region Of Saudi Arabia: A Descriptive Study, Elaf H. Ahmed, Mayar A. Shafei, Leena S. Alsubhi, Noora A. Zarban, Bashair A. Al-Zahrani, Mohammed Shaikhomer
Saudi Medical Journal
Objectives: To describe the effectiveness of HIV guidelines in prevention of mother-to-child transmission (PMTCT). Methods: A retrospective review from January 2009 to December 2018 at the King Abdulaziz University Hospital (KAUH), Jeddah, Kingdom of Saudi Arabia. The main outcome measures were characteristics of HIV-exposed patients and transmission rate. Results: A total of 18 HIV-positive mothers and their 26 infants were included. The mean age of mothers at delivery was 31.69 years, and 50% were under 30 years old. All mothers received lifelong ART, except one who was not diagnosed until the 27th week of gestation. Among the mothers, 83% complied …
Assessment Of Dermatologists’ Perception Of Utilizing Teledermatology During Covid-19 Pandemic In Saudi Arabia, Hatoun M. Almaziad, Abdulrahman I. Alfawzan, Norah K. Alkhayal, Rayan A. Alkhodair
Assessment Of Dermatologists’ Perception Of Utilizing Teledermatology During Covid-19 Pandemic In Saudi Arabia, Hatoun M. Almaziad, Abdulrahman I. Alfawzan, Norah K. Alkhayal, Rayan A. Alkhodair
Saudi Medical Journal
Objectives: To assess teledermatology (TD) perception among dermatologists in the Kingdom of Saudi Arabia during the COVID-19 pandemic and to identify the most common advantages and disadvantages of TD. Methods: We conducted a cross-sectional survey-based study to address Saudi dermatologist perceptions of TD from July 2020 to December 2020, during Covid-19 pandemic. Results: Out of 664 emails sent, 107 complete responses were returned. Approximately 40.2% used TD through phone calls, followed by those who used a virtual clinic (32.7%). Also, the best way to use TD, according to respondents, was for triage before inpatient and outpatient visits. When we compared …
How Has The Covid-19 Pandemic Affect The Rejection Rates And Repeat Reasoning Of Digital Radiography?, Duaa F. Jastaniyyah, Abdulkarim A. Jawhari, Abdullah T. Mugharbel, Mawya A. Khafaji, Sarah H. Albahiti
How Has The Covid-19 Pandemic Affect The Rejection Rates And Repeat Reasoning Of Digital Radiography?, Duaa F. Jastaniyyah, Abdulkarim A. Jawhari, Abdullah T. Mugharbel, Mawya A. Khafaji, Sarah H. Albahiti
Saudi Medical Journal
Objectives: To compare the digital radiology rejection rates and reasoning pre-COVID-19 (PC) and during COVID-19 (DC) from September 2019 to August 2020. Methods: This record-base retrospective study where data were extracted from the radiography equipment (Carestream Health, Rochester, New York, USA) at the Department of Radiology, King Abdulaziz University Hospital, Jeddah, Saudi Arabia over 12 months. The data were equally divided into PC and DC. Results: The DC rejection rate decreased from PC by 2.6% with a significant p =0.00001. During COVID-19 there were 15,376 images of different body parts, versus 23,861 images during PC. Position errors were the main …
Tobacco Smoking And Type 2 Diabetes Mellitus In Gulf Cooperation Council Countries, Abdulmohsen H. Al-Zalabani, Mohammed Z. Aljulifi
Tobacco Smoking And Type 2 Diabetes Mellitus In Gulf Cooperation Council Countries, Abdulmohsen H. Al-Zalabani, Mohammed Z. Aljulifi
Saudi Medical Journal
No abstract provided.
New Research Identifies Cancer Types With Little Survival Improvements In Adolescents And Young Adults
Saudi Medical Journal
No abstract provided.
Who Statement On Advancing The Next Series Of Studies To Find The Origins Of Sars-Cov-2
Who Statement On Advancing The Next Series Of Studies To Find The Origins Of Sars-Cov-2
Saudi Medical Journal
No abstract provided.
Voiding Dysfunction In Children Causes, Management, And Prognosis: A Single-Center Retrospective Study, Mai Banakhar, Khalid Khashoggi, Zaher F. Zaher, Jameela A. Kari
Voiding Dysfunction In Children Causes, Management, And Prognosis: A Single-Center Retrospective Study, Mai Banakhar, Khalid Khashoggi, Zaher F. Zaher, Jameela A. Kari
Saudi Medical Journal
Objectives: To review voiding dysfunction caused by 3 different etiologies; dysfunction voiding syndrome (DVS), neurogenic bladder secondary to spinal dysraphisim (NB), and valve bladder syndrome (VBS). Methods: A single-center retrospective study on children with voiding dysfunction followed up at King Abdulaziz University Hospital, Jeddah, Saudi Arabia from 2005 to 2017. Results: One hundred and ninety-nine children (67.3% boys) were included: Group 1 (n=75, DVS), Group 2 (n=64, NB), and Group 3 (n=60, VBS). Further classification according to the age at presentation; infants (46%), toddlers (27%) and school aged (28%). Management categories: 31% children needed observation only, 25% needed clean intermittent …
Who Recommends Life-Saving Interleukin-6 Receptor Blockers For Covid-19 And Urges Producers To Join Efforts To Rapidly Increase Access
Saudi Medical Journal
No abstract provided.
Early Infection In Post-Autologous Hematopoietic Stem Cell Transplant Patients: Princess Noorah Oncology Center Experience, Roaa S. Gassas, Ahmed N. Absi, Abdulrahman A. Alghamdi, Ahmed S. Alsaeed, Sameer M. Alamoudi, Ihab Y. Hemaidi, Majed D. Alahmadi, Walaa A. Rajkhan, Mannar M. Khalil, Saleem K. Dadah, Ahmed S. Higazi, Amani S. Ahmed
Early Infection In Post-Autologous Hematopoietic Stem Cell Transplant Patients: Princess Noorah Oncology Center Experience, Roaa S. Gassas, Ahmed N. Absi, Abdulrahman A. Alghamdi, Ahmed S. Alsaeed, Sameer M. Alamoudi, Ihab Y. Hemaidi, Majed D. Alahmadi, Walaa A. Rajkhan, Mannar M. Khalil, Saleem K. Dadah, Ahmed S. Higazi, Amani S. Ahmed
Saudi Medical Journal
Objectives: To assess local epidemiology and risk factors for bacterial, fungal, and viral infections among the autologous bone marrow transplant population. Methods: This study is a retrospective correlational cohort design comprising 150 adult patients who underwent autologous transplants at Princess Noorah Oncology Center, Jeddah, Saudi Arabia between 2014 and 2020. Results: The study findings indicate that bacterial infection prevalence differed significantly across the different disease status pre-salvage as patients with the relapsed disease were more likely to have bacterial infections. The median of engraftment days differed significantly between those who had a bacterial infection and those who did not. Interestingly, …
Serostatus Of Igg Antibody Against Mumps Virus In Adult Population Of Al Madinah Al Munawarah, Saudi Arabia, Waleed H. Mahallawi, Mohiadeen M. Kurdi, Nadir A. Ibrahim
Serostatus Of Igg Antibody Against Mumps Virus In Adult Population Of Al Madinah Al Munawarah, Saudi Arabia, Waleed H. Mahallawi, Mohiadeen M. Kurdi, Nadir A. Ibrahim
Saudi Medical Journal
Objectives: To determine the frequency and distribution of mumps-specific IgG antibodies among the healthy adult Saudi population in Al Madinah Al Munawarah, Saudi Arabia, where mandatory vaccination against measles-mumps-rubella (MMR) has been implemented for 30 years. Methods: Qualitative and quantitative indirect enzyme-linked immunosorbent assay was performed to determine the mumps IgG antibody levels in sera collected from 429 individuals, including 224 men and 205 women. Participants were stratified into 3 age groups according to vaccination history (<20, 21-30, and >31 years). Results: The overall seroprevalence of mumps antibodies in our population was 79.0%. The highest proportion of individuals with IgG antibody seropositivity, …
Radiologic Technologists In Saudi Arabia: Does Long-Term Exposure To Radiation Increase The Risk Of Hematological Disorders?, Mohammed Makkawi, Sultan Alasmari, Nasser A. Shubayr, Yazeed I. Alashban, Nashwa H. Eisa, Hussain A. Khairy
Radiologic Technologists In Saudi Arabia: Does Long-Term Exposure To Radiation Increase The Risk Of Hematological Disorders?, Mohammed Makkawi, Sultan Alasmari, Nasser A. Shubayr, Yazeed I. Alashban, Nashwa H. Eisa, Hussain A. Khairy
Saudi Medical Journal
Objectives: To determine the influence of prolonged exposure to radiation based on dosimeter readings on hematological parameters among radiologic technologists (RTs) in Saudi Arabia. Methods: The study was specifically conducted on selected RTs with experience of more than 10 years and the highest thermoluminescent dosimeter (TLD) readings among all RTs in the Radiological Department, Sabya General Hospital, Ministry of Health, Saudi Arabia from August to October 2020. The RTs group was compared with a control group of non-irradiated participants. Blood samples were collected for hematological and coagulation profile evaluation. Results: The acquired radiation dose analysis revealed that the average accumulated …
In This Issuesytematic Revieworiginal Articlescase Report
In This Issuesytematic Revieworiginal Articlescase Report
Saudi Medical Journal
No abstract provided.
Magnet And Receiver-Stimulator Displacement After Cochlear Implantation: Clinical Characters And Management Approaches, Asma Alahmadi, Saad Alenzi, Mohammed Alsheikh, Saeed Alghamdi, Mostafa E. Morra, Khalid M. Badr
Magnet And Receiver-Stimulator Displacement After Cochlear Implantation: Clinical Characters And Management Approaches, Asma Alahmadi, Saad Alenzi, Mohammed Alsheikh, Saeed Alghamdi, Mostafa E. Morra, Khalid M. Badr
Saudi Medical Journal
Objectives: To systematically review the occurrence of magnet or receiver/stimulator displacement following cochlear implant (CI) placement complication and evaluate the existing literature on this topic. Methods: A systematic literature search was conducted using PubMed, Scopus, Web of Science, Virtual Health Library (VHL), and Cochrane Library. Original studies reporting cases of magnet or receiver-stimulator migration occurring as a complication after CI placement were included. The quality of the included studies was evaluated using the National Institutes of Health Quality Assessment Tool for observational studies and CARE checklist for case studies. Results: A total of 36 studies, including 6469 patients, were included. …
Clinical And Functional Results Of Radiofrequency Ablation And Microwave Ablation In Patients With Benign Thyroid Nodules, Mirkhalig Javadov, Emrah Karatay, Mustafa U. Ugurlu
Clinical And Functional Results Of Radiofrequency Ablation And Microwave Ablation In Patients With Benign Thyroid Nodules, Mirkhalig Javadov, Emrah Karatay, Mustafa U. Ugurlu
Saudi Medical Journal
Objectives: To determine how well ultrasound-guidance percutaneous radiofrequency ablation (RFA) and microwave ablation (MWA) performed for benign symptomatic thyroid nodules in terms of clinical and functional outcomes. Methods: Patients who had a thyroid nodule-linked symptoms acting as dysphagia, cosmetic issues, pain, a foreign body sense, hyperthyroidism secondary to autonomous nodules, or concern of malignancy were involved in the study. The primary was the comparison in symptom scores obtained at 1, 3, and 6 months after RFA and MWA. The volume alterations in nodules and alterations in thyroid gland functions were secondary objectives. Results: This prospective study carried out from November …
Risk Factors And Predictors That Influence Sars-Cov-2 Igg Positivity: A Cross-Sectional Study Of Blood Donors In Riyadh, Saudi Arabia, Mohammed F. Alosaimi, Abdulkarim Alhetheel, Khalid A. Aleisa, Abdullah A. Altwerki, Njoud M. Alenezy, Ebtisam M. Almutairi, Leen O. Alothaim, Khalid M. Alayed, Mohammed A. Almazyad, Turki A. Binmoammar, Fahdah A. Alshobaili, Fatimah S. Al-Shahrani, Sarah Alsubaie, Rana M. Hasanato
Risk Factors And Predictors That Influence Sars-Cov-2 Igg Positivity: A Cross-Sectional Study Of Blood Donors In Riyadh, Saudi Arabia, Mohammed F. Alosaimi, Abdulkarim Alhetheel, Khalid A. Aleisa, Abdullah A. Altwerki, Njoud M. Alenezy, Ebtisam M. Almutairi, Leen O. Alothaim, Khalid M. Alayed, Mohammed A. Almazyad, Turki A. Binmoammar, Fahdah A. Alshobaili, Fatimah S. Al-Shahrani, Sarah Alsubaie, Rana M. Hasanato
Saudi Medical Journal
Objectives: To study the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) after pandemic’s peak and before the vaccine enrollment in Riyadh, Saudi Arabia and further explore predictors for SARS-CoV-2 positivity. Methods: A cross-sectional study of 515 blood donors from November 22 to December 17, 2020 was conducted at King Saud University Medical City, Riyadh, Saudi Arabia to look at SARS-CoV-2 immunoglobulin G (IgG) positivity. The participants were asked questions about their demographic characteristics, past SARS-CoV-2 infection, SARS-CoV-2-related symptoms and exposures. Results: The seroprevalence in our study was 12.2% (n=63/515). Being a non-citizen was associated with significantly higher seroprevalence …
Sociodemographic, Clinical Characteristics, And Service Utilization Of Young Children Diagnosed With Autism Spectrum Disorder At A Research Center In Saudi Arabia: The Road To Autism Spectrum Disorder Diagnosis, Abdullah M. Alotaibi, Katelyn A. Craig, Taghreed M. Alshareef, Elham S. Alqathmi, Sarah M. Aman, Hesham M. Aldhalaan, Cheryl L. Oandasan
Sociodemographic, Clinical Characteristics, And Service Utilization Of Young Children Diagnosed With Autism Spectrum Disorder At A Research Center In Saudi Arabia: The Road To Autism Spectrum Disorder Diagnosis, Abdullah M. Alotaibi, Katelyn A. Craig, Taghreed M. Alshareef, Elham S. Alqathmi, Sarah M. Aman, Hesham M. Aldhalaan, Cheryl L. Oandasan
Saudi Medical Journal
Objectives: To assess how clinical services are accessed and utilized by young children with suspected autism spectrum disorder (ASD) and identifying factors that prevent the early identification of developmental concerns and diagnosis. Methods: This retrospective study examined the sociodemographic and clinical characteristics of a convenience sample of children diagnosed with ASD at the Center for Autism Research, Riyadh, Saudi Arabia between 2016 and 2018. The characteristics of ASD assessment and intervention service use were examined. Additionally, we examined the association between sociodemographic, clinical, and service use variables with the child’s age at the time of the parent’s initial concern and …
Physical Inactivity And Its Predictors Among Adolescents In Saudi Arabia: A Cross-Sectional Comparison Between Cities With And Without A Healthy Cities Program, Ibrahim Alasqah, Ilias Mahmud, Leah East, Nada Alqarawi, Kim Usher
Physical Inactivity And Its Predictors Among Adolescents In Saudi Arabia: A Cross-Sectional Comparison Between Cities With And Without A Healthy Cities Program, Ibrahim Alasqah, Ilias Mahmud, Leah East, Nada Alqarawi, Kim Usher
Saudi Medical Journal
Objectives: To estimate the prevalence of insufficient physical activity and excessive screen time among adolescents living in cities participating in the Healthy Cities Program (HCP) and cities not running the program in the Qassim region of Saudi Arabia. Methods: We surveyed 1133 adolescents from the Qassim region using systematic random sampling between April and September 2017. Multivariable logistic regression analyses were conducted to investigate the predictors of insufficient levels of PA and excessive screen time. Results: The prevalence of <60 minutes of moderate- to vigorous-intensity physical activity/day was 82.4% and <3 days of vigorous intensity physical activity/week among adolescents was 59%. There was no significant association between living in healthy cities (HCPs) and insufficient levels of physical activity. The odds of excessive screen time were higher in HCPs than in cities not running the program (NHCPs) (OR: 1.49). The odds of insufficient daily PA (OR: 2.19) are higher among girls than boys. Increasing age is positively associated with insufficient weekly PA (OR: 1.19). The prevalence of excessive recreational screen time is 84.6% with higher odds in HCPs than in NHCPs (OR: 1.51). Conclusion: Our findings report a lack of evidence of any impact of the HCP on adolescents’ physical activity behaviors. This outcome warrants a further in-depth evaluation of the process and outcomes of the HCP in Saudi Arabia.
Patterns And Determinants Of Treatment For Coronary Artery Disease: A Cross-Sectional Study In The Kingdom Of Saudi Arabia, Sameer H. Al-Ghamdi, Khalid Hadi Aldosari, Mansour M. Alajmi
Patterns And Determinants Of Treatment For Coronary Artery Disease: A Cross-Sectional Study In The Kingdom Of Saudi Arabia, Sameer H. Al-Ghamdi, Khalid Hadi Aldosari, Mansour M. Alajmi
Saudi Medical Journal
Objectives: To determine the clinical and coronary angiographic characteristics of patients with coronary artery disease (CAD) and the patterns and determinants of CAD treatment in Kingdom of Saudi Arabia (KSA). Methods: We conducted a cross-sectional study including 242 patients at 3 hospitals in KSA between June 2018 and June 2019. We included all patients aged ≥18 years diagnosed with CAD on angiography. We carried out a multinomial logistic regression to ascertain the determinants of treatment patterns and treatment modalities. Covariates for this multivariate analysis were selected based on univariate regressions. Results: The study population had a mean ± standard deviation …
The Future Of Medical Thoracoscopy In The Kingdom Of Saudi Arabia, Enas M. Batubara, Ahmed S. Ibrahim, Suliman M. Alamro
The Future Of Medical Thoracoscopy In The Kingdom Of Saudi Arabia, Enas M. Batubara, Ahmed S. Ibrahim, Suliman M. Alamro
Saudi Medical Journal
Medical thoracoscopy (MT) has changed how we manage exudative pleural effusion. It is a minimally invasive procedure used as a diagnostic and therapeutic tool in pleural disease. Here, we report a case of a lymphocytic exudative pleural effusion that needed a pleural biopsy for diagnosis. Medical thoracoscopy was performed, a biopsy was taken, and adhesiolysis was performed. Medical thoracoscopy has been practiced for a while worldwide, but it has not been utilized in the Kingdom of Saudi Arabia and as we believe that it is useful in diagnosing exudative pleural effusions. It limits patients in hospital-stay and it may be …
Effectiveness Of Using Tranexamic Acid In Total Hip And Total Knee Arthroplasty: Single Tertiary Center Experience, Khalid Al Sheikh, Ali Alhandi, Abrar Bin Dohaim, Khawlah Ateeq, Khalid Alaqeely
Effectiveness Of Using Tranexamic Acid In Total Hip And Total Knee Arthroplasty: Single Tertiary Center Experience, Khalid Al Sheikh, Ali Alhandi, Abrar Bin Dohaim, Khawlah Ateeq, Khalid Alaqeely
Saudi Medical Journal
Objectives: To measure the effectiveness of tranexamic acid (TXA); in total joint arthroplastyin terms of reducing post-operative blood loss. Methods: A retrospective cohort study in which patients who had underwent total hip arthroplasty (THA) and TKA between 2010-2018 in a single tertiary center. Those had received TXA (group 1) and those who had received no-TXA (group 2) were evaluated. Unpaired student’s t-test was used to compare TXA and no-TXA groups for continuous variables and Chi-square test was used for categorical variables. A p- value<0.05 was considered significant. Results: A total of 385 patients were included, 180 patients received TXA, and 205 patients received no-TXA. Post-operative blood loss was significantly less in TXA group (13.41±9.51, p <0.001). Total drainage output was significantly lower in TXA group compared to no-TXA (373.98±246.12 vs. 487.11±307.13 mL, p <0.001). Blood transfusion units were significantly less in TXA group than in the control group (20 units; 11.1% vs. 50 units; 24.4%, p <0.001). Conclusion: Tranexamic acid use in TKA and THA is effective in reducing post-operative blood loss in terms of drop in Hg level, total drainage output and blood transfusion rate.
Osteoarthritis Linked To Higher Parkinson’S Disease Risk
Osteoarthritis Linked To Higher Parkinson’S Disease Risk
Saudi Medical Journal
No abstract provided.
Joint Covax Statement On The Equal Recognition Of Vaccines
Joint Covax Statement On The Equal Recognition Of Vaccines
Saudi Medical Journal
No abstract provided.
Prevalence Of Covid-19 Antibodies Among Operating Room And Critical Care Staff At A Tertiary Teaching Hospital: A Cross-Sectional Study, Sara H. Farsi, Thamir A. Alandijany, Mansoor Radwi, Ali Farsi, Wadeeah Bahaaziq, Ibrahim Abushoshah, Sherif A. El-Kafrawy, Salma Alsayed, Esam I. Azhar, Abdulaziz Boker
Prevalence Of Covid-19 Antibodies Among Operating Room And Critical Care Staff At A Tertiary Teaching Hospital: A Cross-Sectional Study, Sara H. Farsi, Thamir A. Alandijany, Mansoor Radwi, Ali Farsi, Wadeeah Bahaaziq, Ibrahim Abushoshah, Sherif A. El-Kafrawy, Salma Alsayed, Esam I. Azhar, Abdulaziz Boker
Saudi Medical Journal
Objectives: To identify the prevalence of COVID-19 antibodies among operating room and critical care staff. Methods: In this cross-sectional study, we recruited 319 Healthcare workers employed in the operation theater and intensive care unit of King Abdulaziz University Hospital (KAUH), a tertiary teaching hospital in Jeddah, Saudi Arabia between August 9, 2020 and November 2, 2020. All participants completed a 20-item questionnaire on demographic data and COVID-19 risk factors and provided blood samples. Antibody testing was performed using an in-house enzyme immunoassay and microneutralization test. Results: Of the 319 participants, 39 had detectable COVID-19 antibodies. Five of them had never …
Hspx-Mediated Survival Pathways Of Pathogenic Mycobacteria, Fahad Alhusain
Hspx-Mediated Survival Pathways Of Pathogenic Mycobacteria, Fahad Alhusain
Saudi Medical Journal
Objectives: To optimize an enzyme-linked immunosorbent assay (ELISA) for measuring the HspX protein (α-crystallin) levels and then evaluate its correlation with the accumulation of lipid bodies in Mycobacterium bovis ( M. bovis) during hypoxia and exposure to nitric oxide. Methods: This study was conducted at Prince Sultan Military Medical City, Riyadh, Saudi Arabia between 2016 and 2017. We first optimized ELISA conditions for the detection of HspX. The optimization protocol focused on minimizing concentrations of the capture antibody, detection antibody, and conjugated secondary antibody, and determining the minimum detection limit of the antigen, HspX. Bacteria were grown either in shaking …
Countries Reaffirm Commitment To Ending Polio At Launch Of New Eradication Strategy
Countries Reaffirm Commitment To Ending Polio At Launch Of New Eradication Strategy
Saudi Medical Journal
No abstract provided.
Prevalence And Determinants Of Distress Among Oncology Patients At A Tertiary Care Medical City In Riyadh, Saudi Arabia, Luluh Y. Alsughayer, Lamees A. Altamimi, Futoon S. Alsaleh, Lamya Alsaghan, Ibrahim Alfurayh, Nashwa M. Abdel-Aziz, Khalid A. Alsaleh, Fahad D. Alosaimi
Prevalence And Determinants Of Distress Among Oncology Patients At A Tertiary Care Medical City In Riyadh, Saudi Arabia, Luluh Y. Alsughayer, Lamees A. Altamimi, Futoon S. Alsaleh, Lamya Alsaghan, Ibrahim Alfurayh, Nashwa M. Abdel-Aziz, Khalid A. Alsaleh, Fahad D. Alosaimi
Saudi Medical Journal
Objectives: To estimate the prevalence of distress in patients with cancer in Saudi Arabia and to identify common psychosocial stressors in these patients. We also looked for associations between distress and psychological, sociodemographic, and medical factors. Methods: This cross-sectional study was performed in the oncology outpatient clinic at King Saud University Medical City, Riyadh, Saudi Arabia, from January 2018 to December 2019. It included 280 patients with breast cancer, colorectal cancer, or lymphoma. Sociodemographic information was collected using questionnaire, along with information on medical history and any psychiatric history. Distress was assessed using the Distress Thermometer and Problem List. Satisfaction …
Clinicopathological Characteristics Of Young Versus Older Patients With Breast Cancer: A Retrospective Comparative Study From The Madinah Region Of Saudi Arabia, Abdulkader M. Albasri
Clinicopathological Characteristics Of Young Versus Older Patients With Breast Cancer: A Retrospective Comparative Study From The Madinah Region Of Saudi Arabia, Abdulkader M. Albasri
Saudi Medical Journal
Objectives: To compare the clinicopathological, histological and immunohistochemical features of breast cancer (BC) in between young (≤40 years) and older (>40 years) patients. Methods: This retrospective study included histopathological reports of all patients with primary BC diagnose at the King Fahad Hospital, Madinah, Saudi Arabia between January 2006 and November 2020. Results: During the study period, a total of 708 patients with BC were identified; 173 cases (24.4%) were ≤40 years old and 535 (75.6%) were above 40 years. There were significant differences in tumor size ( p =0.046), tumor grade ( p <0.0001), tumor stage ( p =0.047), lymphovascular invasion ( p <0.0001), and distant metastasis ( p <0.0001) between the 2 groups. Comparing the status of the hormone receptors and molecular subtypes between the 2 age groups, BCs in the younger patients were triple–negative ( p =0.008) in majority of the cases and less likely to be estrogen receptor (ER) and progesterone receptor (PR) hormone receptors–positive ( p =0.0001, p <0.0001). Young patients exhibited the HER2/neu type with more frequent statistical significance ( p =0.016) and the tumor type luminal A ( p =0.002) with less frequent statistical significance compared to old patients. Conclusion: Although BC in young women is uncommon, it may be different with regards to poor prognostic outcomes, which are attributed to more aggressive histopathological features and less favorable receptor status when compared to the cases diagnosed in older women.