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The Effect Of Virtual Reality On Anxiety, Stress, And Hemodynamic Parameters During Cesarean Section: A Randomized Controlled Clinical Trial, Sultan A. Almedhesh, Wafaa T. Elgzar, Heba A. Ibrahim, Hiba A. Osman Apr 2022

The Effect Of Virtual Reality On Anxiety, Stress, And Hemodynamic Parameters During Cesarean Section: A Randomized Controlled Clinical Trial, Sultan A. Almedhesh, Wafaa T. Elgzar, Heba A. Ibrahim, Hiba A. Osman

Saudi Medical Journal

Objectives: To investigate the effect of virtual reality (VR) on anxiety, stress, and hemodynamic parameters during cesarean section (CS). Methods: This is a randomized controlled clinical trial conducted at the operating theatre / Maternal and Children Hospital, Najran, Saudi Arabia from February to October 2021. The study comprised a random sample of 351(176 study and 175 control) low-risk pregnant women undergoing elective CS with regional anesthesia. Data collection was carried out using 5 instruments. Basic and clinical data sheet, maternal hemodynamic parameters assessment sheet, brief measure of preoperative emotional stress, a novel visual facial anxiety scale, and maternal satisfaction scale. …


Evaluation Of The Effects Of Berberine In The Prevention Of Epidural Fibrosis In Rats: An Experimental Research, Emrah Keskin, Çağhan Tönge, Mustafa Kaya, Emre Işık Apr 2022

Evaluation Of The Effects Of Berberine In The Prevention Of Epidural Fibrosis In Rats: An Experimental Research, Emrah Keskin, Çağhan Tönge, Mustafa Kaya, Emre Işık

Saudi Medical Journal

Objectives: To evaluate the effect of berberine (BBR) in preventing the development of epidural fibrosis (EF) after lumbar surgery in rats. Methods: This experimental study was carried out at the animal laboratory of Zonguldak Bülent Ecevit University, Zonguldak, Trurkey, between April 2020 and June 2020. A total of 32 Wistar albino female rats underwent laminectomy and were divided into 4 equal groups. Group 1 did not receive any treatment (control group). In group 2, absorbable gelatin sponge was placed at the surgical site. Groups 3 was administered BBR 10 mg/kg and group 4 was administered BBR 60 mg/kg per oral …


Covid-19 In Pregnant Women: An Evaluation Of Clinical Symptoms And Laboratory Parameters Based On The 3 Trimesters, Şeyhmus Tunç, Mehmet Rifat Göklü, Süleyman Cemil Oğlak Apr 2022

Covid-19 In Pregnant Women: An Evaluation Of Clinical Symptoms And Laboratory Parameters Based On The 3 Trimesters, Şeyhmus Tunç, Mehmet Rifat Göklü, Süleyman Cemil Oğlak

Saudi Medical Journal

Objectives: To investigate the association between the hospitalization rates, symptoms, and laboratory parameters of pregnant women diagnosed with coronavirus disease 2019 (COVID-19) and the gestational week, and determine their symptoms or laboratory parameters predictive of the need for possible admission in the intensive care unit (ICU). Methods: We retrospectively analyzed the symptoms, laboratory parameters, and treatment modalities of 175 pregnant women with COVID-19 who were admitted to a tertiary referral hospital between March 2020 and March 2021 and investigated their association with pregnancy trimesters. Results: The COVID-19-related hospitalization rates in the first trimester was 24.1%, second trimesters was 36%, and …


The Relationship Between Sleep Quality And Menopausal Symptoms Among Postmenopausal Women In Saudi Arabia, Enas M. Abdelaziz, Nadia B. Elsharkawy, Sayeda M. Mohamed Apr 2022

The Relationship Between Sleep Quality And Menopausal Symptoms Among Postmenopausal Women In Saudi Arabia, Enas M. Abdelaziz, Nadia B. Elsharkawy, Sayeda M. Mohamed

Saudi Medical Journal

Objectives: To assess sleep quality and examine its relationship with menopausal symptoms among Saudi postmenopausal women. Methods: We carried out a cross-sectional study of 410 postmenopausal women, aged 50-60 years, visiting Prince Mutaib bin Abdulaziz Hospital, Maternity and Children Hospital, and primary health care clinics, Sakaka, Jouf, Saudi Arabia. The menopause rating scale (MRS) was used to assess menopause symptoms and severity, while the Pittsburgh sleep quality index (PSQI) was used to assess sleep quality. Results: The participants’ age was 53.04±4.15 years, their mean age at natural menopause was 49.14±3.07, and the meantime since their menopause was 6.50±3.84 years. The …


Disease-Specific Quality Of Life In Patients With Diabetic Neuropathy, Mushabab Alghamdi, Lukman F. Owolabi, Bappa Adamu, Magaji G. Taura, Abubakar Jibo, Mohammed Almansour, Saeed N. Alaklabi, Mohammed A. Alghamdi, Isa A. Imam, Reda Abdelrazak, Ahmad Rafaat, Muktar H. Aliyu Apr 2022

Disease-Specific Quality Of Life In Patients With Diabetic Neuropathy, Mushabab Alghamdi, Lukman F. Owolabi, Bappa Adamu, Magaji G. Taura, Abubakar Jibo, Mohammed Almansour, Saeed N. Alaklabi, Mohammed A. Alghamdi, Isa A. Imam, Reda Abdelrazak, Ahmad Rafaat, Muktar H. Aliyu

Saudi Medical Journal

Objectives: To compare health-related quality of life (HRQoL) among patients with diabetes mellitus (DM) and diabetic neuropathy (DN) (D+N) with patients with DM without DN (D-DN) and healthy participants. To evaluate factors associated with poor HRQoL in patients with DN. Methods: This study included 306 participants residing in Bisha, Saudi Arabia. Patients with DM were screened for DN using the Michigan Neuropathy Screening Instrument. Neuropathy severity, disability and HRQoL were determined using the Neuropathy Severity Scale (NSS), the Neuropathy Disability Score (NDS), and the Norfolk Quality of Life-Diabetic Neuropathy (QOL-DN) tool, respectively. Nerve conduction studies (NCSs) were also performed. Results: …


Efficacy Of Breast Cancer Screening Program In Kingdom Of Saudi Arabia, Khalid A. Alsaleh Apr 2022

Efficacy Of Breast Cancer Screening Program In Kingdom Of Saudi Arabia, Khalid A. Alsaleh

Saudi Medical Journal

No abstract provided.


Comments On: Lack Of Association Between Fat Mass And Obesity-Associated Genetic Variant (Rs8050136) And Type 2 Diabetes Mellitus, Abdulghani Alsaeed, Amjad M. Yousuf Apr 2022

Comments On: Lack Of Association Between Fat Mass And Obesity-Associated Genetic Variant (Rs8050136) And Type 2 Diabetes Mellitus, Abdulghani Alsaeed, Amjad M. Yousuf

Saudi Medical Journal

No abstract provided.


Erratum Apr 2022

Erratum

Saudi Medical Journal

No abstract provided.


World Neglected Tropical Diseases Day: Who Calls For Equitable Health Services For All Mar 2022

World Neglected Tropical Diseases Day: Who Calls For Equitable Health Services For All

Saudi Medical Journal

No abstract provided.


Clinical Otorhinolaryngological Presentation Of Covid-19 Patients In Saudi Arabia: A Multicenter Study, Laila M. Telmesani, Danah H. Althomaly, Lamia A. Buohliqah, Roa T. Halawani, Mona M. Ashoor, Marwan J. Alwazzeh, Maha A. Alharbi, Rana F. Almuslem, Sahal S. Arabi, Waleed E. Saleh, Amal Y. Alyosif, Lena S. Telmesani, Abdulaziz S. Alenazi Mar 2022

Clinical Otorhinolaryngological Presentation Of Covid-19 Patients In Saudi Arabia: A Multicenter Study, Laila M. Telmesani, Danah H. Althomaly, Lamia A. Buohliqah, Roa T. Halawani, Mona M. Ashoor, Marwan J. Alwazzeh, Maha A. Alharbi, Rana F. Almuslem, Sahal S. Arabi, Waleed E. Saleh, Amal Y. Alyosif, Lena S. Telmesani, Abdulaziz S. Alenazi

Saudi Medical Journal

Objectives: To assess the otorhinolaryngological (ORL) symptoms, including their prevalence, severity, and early presentations among coronavirus disease-19 (COVID-19) patients in the Saudi population. Methods: This was a multicentric, cross-sectional study carried out on severe acute respiratory syndrome coronavirus-2 positive patients at 3 COVID-19 centres; Imam Abdulrahman Bin Faisal University, King Fahd Hospital of the University, ALKhobar, Qatif Central Hospital, AlQatif, and Ohud Hospital, Al Madinah Al Munawarah, Saudi Arabia. The validated survey consisted of sociodemographic data, general symptoms of COVID-19, and ORL manifestations. Results: A total of 1734 COVID-19 positive patients were included in the study (mean age: 37.7±11.6 years). …


Genotyping Of Dombrock Blood Group System In Blood Donors From Saudi Arabia: A Single-Center Study, Waleed M. Bawazir Mar 2022

Genotyping Of Dombrock Blood Group System In Blood Donors From Saudi Arabia: A Single-Center Study, Waleed M. Bawazir

Saudi Medical Journal

Objectives: To establish the frequency of Dombrock (DO) blood group genotypes in Western Saudi Arabians and to compare the findings with other populations in the 1000 genomes database. Methods: This cross-sectional study was carried out between December 2018 and February 2019. A total of 440 blood samples in ethylenediaminetetraacetic acid tubes were collected from unrelated Saudi Arabian blood donors from Jeddah, Saudi Arabia. Deoxyribonucleic acid was extracted, followed by an allele-specific polymerase chain reaction for DO*01 and DO*02 alleles ( c.793A>G , rs11276 ). The allele and genotype frequencies were counted and compared to those in other populations using …


The Pattern Of Gynecological Malignancies In Al-Madinah Al-Munawarah Region, Saudi Arabia: An Overview Of 6 Years, Nawal H. Almohammadi Mar 2022

The Pattern Of Gynecological Malignancies In Al-Madinah Al-Munawarah Region, Saudi Arabia: An Overview Of 6 Years, Nawal H. Almohammadi

Saudi Medical Journal

Objectives: To describe the frequency and spectrum of different types of gynecological malignancies (malignant tumors of the female genital tract) and to characterize the pattern of gynecological neoplasms in different age groups in Al-Madinah Al-Munawarah, Saudi Arabia. Methods: This 6-year retrospective-design research was carried out on different age groups in Al-Madinah Al-Munawarah region, from June 2015 until June 2021. The patients’ information of all 200 specimens, including age, nationality, tumor site, and pathological disorders was obtained from the Maternity and Children Hospital, Al-Madinah Al-Munawarah. Results: Endometrial cancer was the most common malignancy for women of 31 years and above (69.0%). …


Self-Awareness Of Hba1c And Its Association With Glycemic Control Among Patients With Type 2 Diabetes: A Multicenter Study, Joud S. Almutairi, Turky H. Almigbal, Hiba Y. Alruhaim, Muhammad H. Mujammami, Turki A. Almogbel, Abdullah M. Alshahrani, Mohammed A. Batais, Shaffi A. Shaik Mar 2022

Self-Awareness Of Hba1c And Its Association With Glycemic Control Among Patients With Type 2 Diabetes: A Multicenter Study, Joud S. Almutairi, Turky H. Almigbal, Hiba Y. Alruhaim, Muhammad H. Mujammami, Turki A. Almogbel, Abdullah M. Alshahrani, Mohammed A. Batais, Shaffi A. Shaik

Saudi Medical Journal

Objectives: To measure the self-awareness of hemoglobin A1c (HbA1c) prevalence among type 2 diabetic Saudi patients and its association with glycemic control, thereby identifying those factors that might affect their glycemic control. Methods: This multicenter study was carried out in outpatients’ diabetes clinics in tertiary hospitals in Riyadh, Qassim, and Jeddah, Saudi Arabia. The data was collected using questionnaires. The subject’s self-awareness on the HbA1c test was assessed based on the combined score of 4 questions. The latest HbA1c result before the time of data collection was obtained from medical records. Data was analyzed using bivariate and multivariate statistical methods. …


In This Issueoriginal Articlescase Report Mar 2022

In This Issueoriginal Articlescase Report

Saudi Medical Journal

No abstract provided.


The Effect Of Low Flow Anesthesia With Sevoflurane On Oxidative Status: A Prospective, Randomized Study, Hülya Kaşıkara, Cemile K. Biçer, Almila Şenat, Abdüssamet Yalçın, Cemile Altın, Şemsi Mustafa Aksoy Mar 2022

The Effect Of Low Flow Anesthesia With Sevoflurane On Oxidative Status: A Prospective, Randomized Study, Hülya Kaşıkara, Cemile K. Biçer, Almila Şenat, Abdüssamet Yalçın, Cemile Altın, Şemsi Mustafa Aksoy

Saudi Medical Journal

Objectives: To assess the impact of low-flow, mid-flow, and high-flow sevoflurane anesthesia on the oxidative state by measuring thiol/disulfide levels in patients undergoing surgery. Methods: The study included 99 patients randomly assigned to 3 groups. In the low-flow anesthesia group, the fresh gas flow was diminished to 1 L.min -1 for anesthesia maintenance after 6 L.min -1 was administered for the first 10 minutes. In the mid-flow anesthesia group, fresh gas flow was applied as 2 L.min -1 . In the high-flow anesthesia group, the fresh gas flow was administered as 4 L.min -1 throughout the operation. Blood samples were …


Phenotypic And Genotypic Detection Of Carbapenemase Production Among Gram Negative Bacteria Isolated From Hospital Acquired Infections, Sreeja K. Vamsi, Rama S. Moorthy, Mary N. Hemiliamma, Deepak J. Chanderakant, Shravani Sirikonda Mar 2022

Phenotypic And Genotypic Detection Of Carbapenemase Production Among Gram Negative Bacteria Isolated From Hospital Acquired Infections, Sreeja K. Vamsi, Rama S. Moorthy, Mary N. Hemiliamma, Deepak J. Chanderakant, Shravani Sirikonda

Saudi Medical Journal

Objectives: To identify the carbapenemase producing Gram-negative bacteria (GNB) by phenotypic methods and to confirm the presence of resistant genes using real-time polymerase chain reaction (PCR). Methods: This was a prospective study carried out at the Department of Microbiology, Sri Venkata Sai Medical College and Hospital, Mahabubnagar, India, from March 2018-2021. All samples were screened for carbapenem resistance by disc diffusion method and the VITEK ® 2 compact system (bioMérieux, France). Detection of carbapenemase was carried out using RAPIDEC ® CARBA NP test (Biomeriux Private Limited, South Delhi, India), screening for metallo-β-lactamases (MBL) was carried out by double disk synergy …


Apgar Values Lower Than 7 Associated With Mortality In Premature Newborns: A Retrospective Study, Nayeri Reyes-Saavedra, Patricia C. Castelán-Villagrana, Ivette Mata-Maqueda, Juan C. Solís-Sáinz Mar 2022

Apgar Values Lower Than 7 Associated With Mortality In Premature Newborns: A Retrospective Study, Nayeri Reyes-Saavedra, Patricia C. Castelán-Villagrana, Ivette Mata-Maqueda, Juan C. Solís-Sáinz

Saudi Medical Journal

Objectives: To determine the risk factors associated with mortality in premature newborns (PNB). Methods: An observational, descriptive, and retrospective study, carried out at the General Hospital of San Juan del Rio, Queretaro, Mexico. The medical records of PNB admitted to the Neonatal Intensive Care Unit from January until December 2018 were studied. Results: A total of 136 PNB were included (74 males and 62 females) of whom 16 (11.7%) died (9 males and 7 females). A correlation was observed between gestational age and birth weight with Apgar values at 1 and 5 minutes (r=0.37, p <0.001). A lower birth weight was found in premature infants with infectious diseases, as well as a lower gestational age in relation to respiratory diseases ( p <0.0001). The PNB with Apgar values lower than 7 points at 1 and 5 minutes were more likely to die ( p <0.0001). The PNB with very low birth weight (1-1.49 kg), with less than 28 weeks of gestation, and with infectious pathology showed more probabilities of dying ( p <0.05). Conclusion: Apgar values lower than 7 points in the PNB are associated with the presence of infectious diseases and mortality. Likewise, a lower gestational age represents a lower birth weight, with a higher risk for respiratory and infectious diseases, and consequently an elevated mortality.


Does Sars-Cov-2 Affect Cochlear Functions In Children?, Cigdem F. Koca, Turgut Celik, Agit Simsek, Sukru Aydin, Mehmet Kelles, Seyma Yasar, Omer Erdur Mar 2022

Does Sars-Cov-2 Affect Cochlear Functions In Children?, Cigdem F. Koca, Turgut Celik, Agit Simsek, Sukru Aydin, Mehmet Kelles, Seyma Yasar, Omer Erdur

Saudi Medical Journal

Objectives: To determine the influence of coronavirus disease-19 (COVID-19) on cochlear tasks of children who had COVID-19 previously, and the relevance among disease seriousness and cochlear involvement by otoacoustic emissions (OAEs). Methods: The study included 24 hospitalized children after COVID-19 diagnosis, 23 pediatrics that received outpatient treatment, and 21 children who were without COVID-19 diagnosis as the control group between June 2021 and July 2021. Transient evoked otoacoustic emission (TEOAE), distortion product otoacoustic emission, and contrlateral suppression of otoacoustic emission measurements were carried out for each child. Symptoms of patients, the treatments they received, and the duration of hospitalization of …


The Effect Of Passive Smoking On The Laryngospasm Rate In Children Sedated During The Esophagogastroduodenoscopy, Sibel Seckin Pehlıvan, Ozlem Oz Gergın, Adnan Bayram, Derya Altay, Duran Arslan, Cihangir Biçer, Recep Aksu Mar 2022

The Effect Of Passive Smoking On The Laryngospasm Rate In Children Sedated During The Esophagogastroduodenoscopy, Sibel Seckin Pehlıvan, Ozlem Oz Gergın, Adnan Bayram, Derya Altay, Duran Arslan, Cihangir Biçer, Recep Aksu

Saudi Medical Journal

Objectives: To investigate the rate of laryngospasm with sedation during the esophagogastroduodenoscopy (EGD) procedure in children exposed to passive smoking and to examine the frequency of complications due to laryngospasm. Methods: A single-blind, prospective, observational study with a total of 518 patients evaluated according to the American Society of Anesthesiologists (ASA) physical status as classification I-II, aged between 1-18 years, and planned to undergo an EGD procedure, were included. Age, gender, weight, ASA assessment, exposure to smoking (the mother, the father, both parents were smokers, or not exposed to smoking), drug doses used in sedation, and anesthesia-related complications, such as …


Reliability And Validity Study Of The Translated Arabic Version Of Moorehead-Ardelt Quality Of Life Questionnaire Ii, Saud Aldeghaither, Mohammed Alnaami, Abdullah Aldohayan, Fahad Bamehriz, Sarah Alhaizan, Mohammed Aldeghaither, Abdullah Almunifi Mar 2022

Reliability And Validity Study Of The Translated Arabic Version Of Moorehead-Ardelt Quality Of Life Questionnaire Ii, Saud Aldeghaither, Mohammed Alnaami, Abdullah Aldohayan, Fahad Bamehriz, Sarah Alhaizan, Mohammed Aldeghaither, Abdullah Almunifi

Saudi Medical Journal

ABSTRACT Objectives: To generate a translated Arabic adaptation of the revised Moorehead-Ardelt Quality of Life Questionnaire II (MA-II), then to assess its reliability and validity. Methods: The MA-II was translated to Arabic by 3 independent translators. Next, a concise translation, developed from the 3 translations, was re-translated to English and was compared with the original questionnaire. Both the reliability and the validity of the Arabic MA-II were assessed in 144 patients struggling with obesity before and after bariatric procedures at Khalid University Hospital, Riyadh, Saudi Arabia. Apart from the demographic data, both the MA-II and the 36-item short-form health survey …


Don’T Overlook Flank Pain In Apparently Asymptomatic Covid-19 Cases: A Case Report And Literature Review, Ammar Ashraf, Ahmed M. Abdelrahman Mar 2022

Don’T Overlook Flank Pain In Apparently Asymptomatic Covid-19 Cases: A Case Report And Literature Review, Ammar Ashraf, Ahmed M. Abdelrahman

Saudi Medical Journal

ABSTRACT An outbreak of novel coronavirus disease-2019 (COVID-19) was reported in Wuhan, China, in December 2019, which was later declared a global pandemic by the World Health Organization (WHO) in March 2020. It is a life-threatening contagious infection with infected patients usually presenting with respiratory tract symptoms, although the disease can affect other multiple organs. Coronavirus disease-2019 infection is a hypercoagulable state associated with serious thrombotic complications, particularly in critically ill patients. However, these thrombotic complications are also being reported as a presenting symptom in asymptomatic and mildly symptomatic cases of COVID-19 infection in the absence of any other predisposing …


Improving Coordination Of Lung Cancer Care At A Tertiary Healthcare Center In Saudi Arabia, Abeer Alkhathlan, Razan Alfaiz, Ghaida Almusallam, Esraa Arabi, Mohammad Alkaiyat, Abdulrahman Jazieh Mar 2022

Improving Coordination Of Lung Cancer Care At A Tertiary Healthcare Center In Saudi Arabia, Abeer Alkhathlan, Razan Alfaiz, Ghaida Almusallam, Esraa Arabi, Mohammad Alkaiyat, Abdulrahman Jazieh

Saudi Medical Journal

ABSTRACT Objectives: To evaluate the impact of coordination of care of lung cancer in a tertiary care center. Methods: A retrospective study was carried out on all patients diagnosed with lung cancer between 2016-2017 at King Abdulaziz Medical City, Riyadh, Saudi Arabia. Data were collected from medical records, which included demographic data, the interval between cancer suspicion and definitive therapy, multidisciplinary tumor board (MTB) data, and palliative care. Results: A total of 60 (41 males and 19 females) cases of lung cancer were analyzed. The majority of patients had adenocarcinoma (63.3%) and stage IV (70%) lung cancer. A total of …


Clinical Outcomes Of Simultaneous Bilateral Total Knee Arthroplasty.: A Tertiary-Center Experience, Abdullah O. Bawazir, Hossein A. Filimban, Nawaf Halabi, Salman W. Bafageeh, Rayan Halabi, Saeed Albukhari, Eyad A. Alakkas, Habib Al Etani, Abdullah Basalaim, Ahmed Alturkistan, Bander Hetaimish Mar 2022

Clinical Outcomes Of Simultaneous Bilateral Total Knee Arthroplasty.: A Tertiary-Center Experience, Abdullah O. Bawazir, Hossein A. Filimban, Nawaf Halabi, Salman W. Bafageeh, Rayan Halabi, Saeed Albukhari, Eyad A. Alakkas, Habib Al Etani, Abdullah Basalaim, Ahmed Alturkistan, Bander Hetaimish

Saudi Medical Journal

ABSTRACT Objectives: To characterize patients who underwent simultaneous bilateral total knee arthroplasty (simBTKA) and study the outcomes of surgery along with complication rates. Methods: This is a retrospective study carried out at King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia. The study included patients who had undergone simultaneous bilateral total knee replacement from January 2010 until June 2021. Results: The median age of our patients was 64 (Q1-Q3: 59-70) years, 76 (13.2%) males and 393 (83.8%) were females. Hypertension was the most common associated comorbidity (56.29%) and primary osteoarthritis was the most common indication of surgery (96.8%). The …


Who Publishes New Global Data On The Use Of Clean And Polluting Fuels For Cooking By Fuel Type Mar 2022

Who Publishes New Global Data On The Use Of Clean And Polluting Fuels For Cooking By Fuel Type

Saudi Medical Journal

No abstract provided.


An Evaluation Of Public Recognition And Attitude Towards Depression, Muneera Al Hussaini, Ahmed H. Aljadani Feb 2022

An Evaluation Of Public Recognition And Attitude Towards Depression, Muneera Al Hussaini, Ahmed H. Aljadani

Saudi Medical Journal

No abstract provided.


Lack Of Association Between Fat Mass And Obesity-Associated Genetic Variant (Rs8050136) And Type 2 Diabetes Mellitus, Amjad M. Yousuf, Firoz A. Kannu, Talha M. Youssouf, Fatimah N. Alsuhaimi, Abdulaziz M. Aljohani, Fayez H. Alsehli, Omar F. Khabour, Yahya A. Almutawif, Mustafa A. Najim, Hatem A. Mahmood Feb 2022

Lack Of Association Between Fat Mass And Obesity-Associated Genetic Variant (Rs8050136) And Type 2 Diabetes Mellitus, Amjad M. Yousuf, Firoz A. Kannu, Talha M. Youssouf, Fatimah N. Alsuhaimi, Abdulaziz M. Aljohani, Fayez H. Alsehli, Omar F. Khabour, Yahya A. Almutawif, Mustafa A. Najim, Hatem A. Mahmood

Saudi Medical Journal

Objectives: To study the genotype and allele frequency of the fat mass and obesity-associated (FTO) rs8050136 A>C genetic variant and investigate its association with type 2 diabetes mekkitus (T2DM) parameters. Methods: This study was carried out on 118 diabetic patients and 106 healthy individuals (control) from Prince Mohammed bin Abdulaziz Hospital, Al Madinah Al Munawarah, Saudi Arabia. The TaqMan single-nucleotide polymorphism (SNP)genotyping assay was used for rs8050136 genotyping. Results: The frequency of the genotype AA was the same among T2DM and healthy control groups (21%). However, the frequency of genotype CC was 19.5% in T2DM patients and 24.5% in …


Indices Of Insulin Resistance And Adiposity Can Detect Obesity-Related Morbidity In Pediatrics, Marwa H. Abdelhamed, Shaimaa Salah, Khloud K. Alqudsi, Majd M. Jan, Duaa K. Alahdal, Saher A. Alfaifi, Nuha M. Jafar, Naseem Y. Alyahyawi, Abdulmoein A. Al-Agha Feb 2022

Indices Of Insulin Resistance And Adiposity Can Detect Obesity-Related Morbidity In Pediatrics, Marwa H. Abdelhamed, Shaimaa Salah, Khloud K. Alqudsi, Majd M. Jan, Duaa K. Alahdal, Saher A. Alfaifi, Nuha M. Jafar, Naseem Y. Alyahyawi, Abdulmoein A. Al-Agha

Saudi Medical Journal

Objectives: To evaluated obesity-related morbidity prevalence among overweight/obese children and adolescents in Saudi Arabia, adiposity indicators and insulin resistance as obesity-related morbidity predictors. Methods: We enrolled 318 overweight/obese children attending a Pediatric Endocrinology Clinic at King Abdulaziz University Hospital, Saudi Arabia, aged 2–20 years in this retrospective cross-sectional study from September 2019 to March 2021. All children had nutritional obesity, and their body mass index (BMI) standard deviation score was higher than one standard deviation score above the mean for their age and gender. Clinical adiposity indices including BMI, waist circumference (WC), waist-hip ratio (WHR), and bioimpedance analysis (BIA) of …


Occupational And Environmental Exposures, The Association With Chronic Sinusitis, Feras M. Alkholaiwi, Rahaf R. Almutairi, Danah M. Alrajhi, Basma A. Alturki, Atheer G. Almutairi, Faris H. Binyousef Feb 2022

Occupational And Environmental Exposures, The Association With Chronic Sinusitis, Feras M. Alkholaiwi, Rahaf R. Almutairi, Danah M. Alrajhi, Basma A. Alturki, Atheer G. Almutairi, Faris H. Binyousef

Saudi Medical Journal

Objectives: To find the association between environmental and occupational exposures and chronic rhinosinusitis (CRS) development. Methods: The Preferred Reporting Items Of Systematic Reviews Guidelines were used when a systematic literature review was conducted to find all published cases of CRS by searching PubMed database and Google Scholar. Published articles between 1989 and 2021 that reported chronic and occupational rhinosinusitis were included. However, articles that reported allergic rhinitis or upper airway diseases and non-English articles were excluded from this study. Results: A total of 97 articles were extracted initially, and 15 articles were reviewed after excluding 82 articles that did not …


Survival And Prognostic Factors In Women Treated For Epithelial Ovarian Cancer In Western Region Of Saudi Arabia, Khalid H. Sait, Mohammad Z. Alam, Absarul Haque, Hesham K. Sait, Maram K. Sait, Nisreen M. Anfinan Feb 2022

Survival And Prognostic Factors In Women Treated For Epithelial Ovarian Cancer In Western Region Of Saudi Arabia, Khalid H. Sait, Mohammad Z. Alam, Absarul Haque, Hesham K. Sait, Maram K. Sait, Nisreen M. Anfinan

Saudi Medical Journal

Objectives: To assess survival and prognostic factors among women with epithelial ovarian cancer in Western Saudi Arabia. Methods: A retrospective cohort study was carried out between October 2000 and May 2018, reviewing clinical and pathology data of all women who underwent staging or debulking surgery for epithelial ovarian cancer. Analysis of disease-free survival (DFS), overall survivals (OS) and the associated factors used Kaplan-Meier method in addition to cox multivariate regression. Results: A total of 144 patients were included (median age=49.5 years), with a median follow-up time was 3.4 years. Majority (59.7%) of the patients were diagnosed at an advanced stage …


The Relationship Between The Visceral Adiposity Index And Carotid Atherosclerosis In Different Genders And Age Groups, Jing Cao, Shengpeng Liu, Hebin Xie, Yu Zhang, Yalin Zeng Feb 2022

The Relationship Between The Visceral Adiposity Index And Carotid Atherosclerosis In Different Genders And Age Groups, Jing Cao, Shengpeng Liu, Hebin Xie, Yu Zhang, Yalin Zeng

Saudi Medical Journal

Objectives: To investigate the possible relationship between visceral adiposity index (VAI) and carotid atherosclerosis(CAS) in different genders and age groups in China. Methods: This study was an observational cross-sectional study and included 1996 participants who were health examination . From January 2018 to June 2019, people over 18 years old who had physical examinations were included in the study. Each participant completed a standard questionnaire, anthropometric measurements, ultrasonic examination, and provided blood samples for biochemical measurements. Regression models were utilized to evaluate the relationship between VAI and the CAS risk. An receiver operating characteristic (ROC) was utilized to predict VAI …