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Salt Losing Nephropathy Simulating Congenital Adrenal Hyperplasia In An Infant, Jameela A. Kari, Hussain A. Bamashmous, Abdulmoein E. Al-Agha, Hisham A. Mosli Jul 2002

Salt Losing Nephropathy Simulating Congenital Adrenal Hyperplasia In An Infant, Jameela A. Kari, Hussain A. Bamashmous, Abdulmoein E. Al-Agha, Hisham A. Mosli

Saudi Medical Journal

Pseudo-hypoaldosteronism occurring predominately in male infants has been reported in association with a spectrum of urologic diseases including obstructive uropathy. This is thought to reflect tubule unresponsiveness to aldosterone. We report a case, which was misdiagnosed as a case of congenital adrenal hyperplasia and treated inappropriately with hydrocortisone and fludrocortisone for 12-months before he had a urinary tract infection and was discovered to have obstructive uropathy on ultrasound. He presented with vomiting, dehydration, hyperkalemia, hyponatremia and metabolic acidosis. His initial 17 hydroxyprogestrone was high. His electrolytes improved to normal after relieving the obstruction by vesicostomy and his treatment weaned slowly …


Spontaneous Rupture Of Hepatocellular Carcinoma, Faisal M. Al-Mashat, Abdulrahman M. Sibiany, Rashid H. Kashgari, Abdulraouf A. Maimani, Asim O. Al-Radi, Ibrahim A. Balawy Jul 2002

Spontaneous Rupture Of Hepatocellular Carcinoma, Faisal M. Al-Mashat, Abdulrahman M. Sibiany, Rashid H. Kashgari, Abdulraouf A. Maimani, Asim O. Al-Radi, Ibrahim A. Balawy

Saudi Medical Journal

Hepatocellular carcinoma is the most common malignancy among males and the 7th among female patients in the Kingdom of Saudi Arabia. This is due to the endemicity of hepatitis B and hepatitis C. Spontaneous rupture of hepatocellular carcinoma is rare. We report 4 cases of spontaneous rupture of hepatocellular carcinoma. Initial control of bleeding was achieved surgically in 3 patients and by embolization in the 4th patient. All patients had very good hepatic reserve as reflected by Child-Pough scoring (A & B). We found that the incidence of ruptured hepatocellular carcinoma among 85 patients was 4.7%. The prognosis of this …


A Comparison Between The Effects Of Diltiazem And Isosorbide Dinitrate On Digoxin Pharmacodynamics And Kinetics In The Treatment Of Patients With Chronic Ischemic Heart Failure, Afaf A. Mahgoub, Azza H. El-Medany, Ahmed S. Abdulatif Jun 2002

A Comparison Between The Effects Of Diltiazem And Isosorbide Dinitrate On Digoxin Pharmacodynamics And Kinetics In The Treatment Of Patients With Chronic Ischemic Heart Failure, Afaf A. Mahgoub, Azza H. El-Medany, Ahmed S. Abdulatif

Saudi Medical Journal

OBJECTIVE: To evaluate the effect of an arteriolar dilator (diltiazem hydrochloride) versus a venodilator (isosorbide dinitrate) on digoxin kinetics and to estimate the efficacy and tolerability of these vasodilators when combined with digoxin for 10 days therapy in patients with congestive heart failure secondary to ischemic heart disease. METHODS: A double blind randomized cross over study was carried out to investigate the effect of an arteriolar dilator (diltiazem hydrochloride 180 mg/day orally) versus a venodilator (isosorbide dinitrate 30 mg/day orally) on digoxin kinetics (0.25 mg/day orally), after 10 days therapy in patients with heart failure due to ischemic heart disease. …


Sero-Response To Measles-Mumps-Rubella Vaccine Campaign In Saudi Arabia, Yagob Y. Al-Mazrou, Mohamed K. Khalil, Salah Tumsah, Yasser S. Al-Ghamdi, Mohamed H. Al-Jeffri, Andore B. Tischer, Ameen A. Mishkhas, Mostafa Eissa Jun 2002

Sero-Response To Measles-Mumps-Rubella Vaccine Campaign In Saudi Arabia, Yagob Y. Al-Mazrou, Mohamed K. Khalil, Salah Tumsah, Yasser S. Al-Ghamdi, Mohamed H. Al-Jeffri, Andore B. Tischer, Ameen A. Mishkhas, Mostafa Eissa

Saudi Medical Journal

OBJECTIVE: To evaluate the measles-mumps-rubella vaccine campaign targeting primary school children in the Kingdom of Saudi Arabia during the months of January and February 2000. METHODS: Pre and post measles-mumps-rubella vaccine blood samples were collected from 54 children from the first grade and 96 children from the 6th grade. Antibodies against measles, mumps and rubella were assayed using enzyme immunoassay and a backup test of plaque neutralization test. This assay was carried out at the Reference Center, Koch Institute, Berlin, Germany. RESULTS: When the backup test results were added, 96%-98% of children had protection level against measles before the campaign. …


Ethical Considerations In The Prevention And Management Of Genetic Disorders With Special Emphasis On Religious Considerations, Mohammed A. Albar Jun 2002

Ethical Considerations In The Prevention And Management Of Genetic Disorders With Special Emphasis On Religious Considerations, Mohammed A. Albar

Saudi Medical Journal

Genetic diseases include not only single gene disoders, but multifactorial, somatic cell genetic disorders, mitochondrial and even chromosomal. One in 4 adults will suffer from a multifactorial or a somatic cell genetic disease. The common diseases in the community have a hereditary component namely diabetes mellitus, hypertension, ischemic heart diseases and many types of cancer. Even monogenic diseases which affect a small number of the newborns (2%-3%), have a greater impact on childhood diseases up to age 15 years. Therefore, it is imperative to scrutinize the available methods of prevention and management of genetic disorders, their ethical implications, and since …


Thyroid Disease And Pregnancy, Omar M. Malkawi Jun 2002

Thyroid Disease And Pregnancy, Omar M. Malkawi

Saudi Medical Journal

Several important issues must be considered when thyroid disorders occur during pregnancy. These include establishing the diagnosis (including an understanding of the effect of pregnancy and its hormonal changes on the immune system in general and the thyroid function in particular) treatment and uneventful maternal and neonatal outcome. The evaluation and treatment of women with thyroid disease during pregnancy parallels that of nonpregnant women and men, but presents unique problems. In addition some types of thyroid disorders occur only during pregnancy and the postpartum period. Pregnancy complicated by some thyroid disorders is associated with an increased rate of complications to …


Job Satisfaction Of Nurses In Ministry Of Health Hospitals In Riyadh, Saudi Arabia, Hanan A. Al-Ahmadi Jun 2002

Job Satisfaction Of Nurses In Ministry Of Health Hospitals In Riyadh, Saudi Arabia, Hanan A. Al-Ahmadi

Saudi Medical Journal

OBJECTIVE: To examine the magnitude and determinants of job satisfaction in nurses working in Ministry of Health hospitals Riyadh, Kingdom of Saudi Arabia. METHODS: A modified version of the Minnesota Job Satisfaction Questionnaire is used to survey 500 nurses in 9 Ministry of Health hospitals in Riyadh, Kingdom of Saudi Arabia. Three hundred and sixty six nurses from different nationalities responded to the questionnaire (response rate 73%). Data analysis consisted of descriptive statistics, t-tests, one way-analysis of variance, correlation analysis, and regression analysis. RESULTS: Overall job satisfaction was found to be moderate. The most important determinants of job satisfaction are: …


Disseminated Intravascular Coagulation And Massive Obstetric Hemorrhage. Management Dilemma, Lulu A. Al-Nuaim, Mohamed S. Mustafa Jun 2002

Disseminated Intravascular Coagulation And Massive Obstetric Hemorrhage. Management Dilemma, Lulu A. Al-Nuaim, Mohamed S. Mustafa

Saudi Medical Journal

OBJECTIVE: The objective of this retrospective study is to reflect on our experience on an optimal management for major postpartum hemorrhage, which would prevent the occurrence and complications of disseminated intravascular coagulation and minimize maternal mortality and morbidity. METHODS: Ten cases out of the 30,000 of total deliveries of severe obstetric hemorrhage associated with disseminated intravascular coagulation were studied. This study was carried out over a 7 year period, October 1988 through to September 1995, at the Obstetric Unit, King Khalid University Teaching Hospital, Riyadh, Kingdom of Saudi Arabia. RESULTS: All of the 10 women received packed red blood cells, …


The Effect Of Metformin Plus Clomiphene Citrate On Ovulation And Pregnancy Rates In Clomiphene-Resistant Women With Polycystic Ovary Syndrome, Hasan Y. Malkawi, Hussein S. Qublan Jun 2002

The Effect Of Metformin Plus Clomiphene Citrate On Ovulation And Pregnancy Rates In Clomiphene-Resistant Women With Polycystic Ovary Syndrome, Hasan Y. Malkawi, Hussein S. Qublan

Saudi Medical Journal

OBJECTIVE: To study the effect of metformin in combination with clomiphene citrate, as compared with placebo plus clomiphene citrate, on the ovulation and pregnancy rates in clomiphene citrate-resistant women with polycystic ovary syndrome. METHODS: This study was carried out at King Hussein Medical Center, Amman, Jordan, during the period January 2001 through to July 2001. Twenty-eight clomiphene citrate-resistant polycystic ovary syndrome women were evaluated prospectively for 6 treatment cycles by receiving metformin, 850mg twice daily throughout the cycle along with 50 mg clomiphene citrate, starting on day 5-9 of the same cycle (N=16), or by taking placebo with clomiphene citrate …


Rate And Risk Factors Of Surgical Site Infections With Antibiotic Prophylaxis, Yahia A. Raja'a, Aisha R. Salam, Yahia A. Salih, Mosleh S. Salman, Lyla S. Al-Baseer, Najib A. Al-Kirshi, Najib S. Al-Jalal Jun 2002

Rate And Risk Factors Of Surgical Site Infections With Antibiotic Prophylaxis, Yahia A. Raja'a, Aisha R. Salam, Yahia A. Salih, Mosleh S. Salman, Lyla S. Al-Baseer, Najib A. Al-Kirshi, Najib S. Al-Jalal

Saudi Medical Journal

OBJECTIVE: This study is aimed at determining the incidence of surgical site infections, with antibiotic use. Furthermore, to correlate infection with type of operations, length of intervention, number of stitches, pre-operative hospitalization, age and sex of the patient. METHODS: All Yemeni patients (N=601) who underwent surgical intervention, with preoperative antibiotic prophylaxis, at Al-Kuwait University Hospital, Sana9a, Republic of Yemen, during 1st August 2000 through to 30th November 2000 were followed up until stitch removal or discharge. Data was registered in a spreadsheet and processed statistically by statistical package for social sciences 10.0. RESULTS: Overall incidence of surgical site infections was …


Malaria Parasitemia During Delivery, Sayed M. Ahmed, Ahmed A. Mohamedani, Ali B. Habour, Ali A. Sadek Jun 2002

Malaria Parasitemia During Delivery, Sayed M. Ahmed, Ahmed A. Mohamedani, Ali B. Habour, Ali A. Sadek

Saudi Medical Journal

OBJECTIVE: The aim of this study is to investigate the impact of plasmodium falciparum infection in parturient women in Central Sudan where malaria transmission is mesoendemic. The purpose of this paper is to find out the prevalence of malaria parasitemia and the risk of anemia among parturient women and to suggest appropriate strategies to lower their prevalence rates. METHODS: This prospective study was conducted at Medani Teaching Hospital, Sudan, a tertiary regional referral center, during the period January 1997 through to December 1997. All cases were admitted during labor to the delivery room and were clinically suspected to have malaria. …


Surgically Treated Transitional Cell Carcinomas Of The Bladder. The Role Of Radical Surgery, Muneer A. Al-Ali, Dawoud M. Kashmoula, Loay F. Haddad Jun 2002

Surgically Treated Transitional Cell Carcinomas Of The Bladder. The Role Of Radical Surgery, Muneer A. Al-Ali, Dawoud M. Kashmoula, Loay F. Haddad

Saudi Medical Journal

OBJECTIVE: To assess the treatment outcome and differentiate between the individual behavior of the tumor stages that were studied (Ta, T1, and T2a) with special reference to T2a tumors. METHODS: This study was carried out at Al-Rasheed Military Hospital, Baghdad, Iraq, during a 12 year period. Fifty-six patients with Ta, T1, and T2a (superficial invasion of muscularis propria) transitional cell carcinomas of the bladder, have been retrospectively analyzed. They were treated surgically with either transurethral of the bladder tumor (N=45) or radical surgery (N=11). Tumors with frequent recurrences or mulifocal or extending to the ureter or vesical outlet were treated …


Brca1 And Brca2 Mutations In Breast Cancer Patients From Saudi Arabia, El-Harith A. El-Harith, Maha S. Abdel-Hadi, Diana Steinmann, Thilo Dork Jun 2002

Brca1 And Brca2 Mutations In Breast Cancer Patients From Saudi Arabia, El-Harith A. El-Harith, Maha S. Abdel-Hadi, Diana Steinmann, Thilo Dork

Saudi Medical Journal

OBJECTIVE: The aim of this pilot study was to screen the major segments of the BRCA1 and BRCA2 genes for disease-associated mutations in Arab and Asian women with breast cancer from the Kingdom of Saudi Arabia. METHODS: Deoxyribonucleic acid samples from 29 Arab women and 11 Asian women, with unilateral breast cancer were investigated for BRCA1 and BRCA2 mutations. For this purpose single strand conformation polymorphism and direct nucleotide sequencing techniques were employed. This study was carried out at King Fahad Hospital of the University, Al-Khobar, Kingdom of Saudi Arabia, during the time frame March 2000 through to August 2001. …


Point Prevalence Of Type B Tympanogram In Children, Siraj M. Zakzouk, Khariya A. Abduljawad Jun 2002

Point Prevalence Of Type B Tympanogram In Children, Siraj M. Zakzouk, Khariya A. Abduljawad

Saudi Medical Journal

OBJECTIVE: Otitis media with effusion is a common disease; it is primarily a disease of children. Otitis media with effusion was found as the most common cause of hearing impairment among children. The prevalence varied in different populations. Using otoscopy and tympanometry usually gives a valuable indication of the presence of otitis media with effusion. The aim of this study is to determine the point prevalence of type B tympanogram as a diagnostic and indication of the presence of otitis media with effusion. METHODS: This study was carried out during the period September 1997 through to May 2000. The study …


Prevalence Of Mental Illness Among Saudi Adult Primary-Care Patients In Central Saudi Arabia, Abdallah D. Al-Khathami, Danny O. Ogbeide Jun 2002

Prevalence Of Mental Illness Among Saudi Adult Primary-Care Patients In Central Saudi Arabia, Abdallah D. Al-Khathami, Danny O. Ogbeide

Saudi Medical Journal

OBJECTIVE: To determine the prevalence of mental illness morbidity among Saudi adult primary care patients from Al-Kharj, Kingdom of Saudi Arabia. METHODS: This is a cross-sectional epidemiological study of the prevalence of mental illness morbidity in a randomly selected sample of 609 Saudi adult patients, aged from 15 years to 65 years who attended Family and Community Medicine Clinic, Armed Forces Hospital, Al-Kharj, Kingdom of Saudi Arabia, from July 2000 to November 2000. The Rahim Anxiety-Depression Scale was used in the evaluation. RESULTS: In this study, 609 Saudi patients were screened. Their mean age ± standard deviation was 33.72 ± …


Malignant Familial Long Qt Syndrome, Raghavan Subramanyan, Poothirikovil Venugopalan Jun 2002

Malignant Familial Long Qt Syndrome, Raghavan Subramanyan, Poothirikovil Venugopalan

Saudi Medical Journal

We report a family with congenital long QT syndrome, an inherited disorder of myocardial repolarization in which affected individuals have prolongation of corrected QT interval on the electrocardiogram and a tendency to develop ventricular arrhythmia, leading to syncope, convulsion or sudden death. Our family is characterized by several affected members (11/16), early onset of symptoms, malignant course prior to diagnosis and good response to beta-blocker therapy. The genetic basis of long QT syndrome has been traced to defective proteins encoding cardiac ion channels. Diagnosis is based on an unexplained prolongation of QT interval >0.45 second in the presence of suggestive …


Membranoproliferative Glomerulonephritis Due To Hepatitis C In Renal Allograft, Ahmed S. Al-Arrayed, Sara M. George, Kamaraju S. Ratnakar Jun 2002

Membranoproliferative Glomerulonephritis Due To Hepatitis C In Renal Allograft, Ahmed S. Al-Arrayed, Sara M. George, Kamaraju S. Ratnakar

Saudi Medical Journal

Membranoproliferative glomerulonephritis type 1 is an etiologically divergent disorder. Hepatitis C with or without cryoglobulinemia is considered one of the principal causes of de novo and post transplant membranoproliferative glomerulonephritis type 1. A 49-year-old male who underwent renal allograft for end stage renal disease developed proteinuria and positive hepatitis C serology during the post-transplant period. This was associated with moderate hepatic dysfunction, which necessitated both liver and renal biopsies. Features of both chronic active hepatitis and membranoproliferative glomerulonephritis type 1 were seen as a result of histological examination of both liver and renal biopsies. Ultra structural studies showing mesangial and …


Researcher's Guide To Health Statistics, Ibrahim Mansoor Jun 2002

Researcher's Guide To Health Statistics, Ibrahim Mansoor

Saudi Medical Journal

No abstract provided.


A Survey Of The Reasons For Vasectomy Refusal In Couples Who Have Chosen Tubectomy As Their Contraceptive Method, Zahra Kamyabi Jun 2002

A Survey Of The Reasons For Vasectomy Refusal In Couples Who Have Chosen Tubectomy As Their Contraceptive Method, Zahra Kamyabi

Saudi Medical Journal

No abstract provided.


Cecal Vascule. An Overlooked Mechanism Of Cecal Volvulus, Abdulmajeed Al-Abdulkareem, Alaa Abdul Jabbar Jun 2002

Cecal Vascule. An Overlooked Mechanism Of Cecal Volvulus, Abdulmajeed Al-Abdulkareem, Alaa Abdul Jabbar

Saudi Medical Journal

No abstract provided.


Screening For Congenital Hypothyroidism, Gerard Henry, Samia H. Sobki, Johara M. Othman May 2002

Screening For Congenital Hypothyroidism, Gerard Henry, Samia H. Sobki, Johara M. Othman

Saudi Medical Journal

OBJECTIVE: To review the screening program for congenital hypothyroidism in the Riyadh Al-Kharj Hospital Programme, Riyadh, Kingdom of Saudi Arabia, and to investigate the clinical and biochemical characteristics of affected infants. METHODS: The study was carried out from 1985 to 2000 in the Clinical Chemistry Division, Department of Pathology, Riyadh Armed Forces Hospital, Kingdom of Saudi Arabia. Laboratory data and case notes of infants diagnosed with congenital hypothyroidism were used to supply the relevant data and information. RESULTS: One hundred and twenty-one thousand, four hundred and four infants were screened over a period of nearly 15 years. The overall incidence …


Use Of Antiplatelets And Lipid Lowering Therapy In Patients With Peripheral Vascular Disease, Abdulaziz S. Aldawood, Roman Jaeschke May 2002

Use Of Antiplatelets And Lipid Lowering Therapy In Patients With Peripheral Vascular Disease, Abdulaziz S. Aldawood, Roman Jaeschke

Saudi Medical Journal

OBJECTIVE: To investigate the use of antiplatelet and lipid lowering therapy among patients undergoing peripheral vascular surgery, and to compare their use with that reported among a similar population of patients in Canada. METHODS: Chart review of a cohort of 52 patients undergoing peripheral vascular surgery. The study was carried out at King Fahad National Guard Hospital, Kingdom of Saudi Arabia in May 2000. RESULTS: On discharge, less than 50% of the patients received any antiplatelet or antithrombotic medication. Only 13% of the patients received lipid-lowering therapy. Those findings parallel those of Canadian publications. CONCLUSION: Current literature supports the use …


Adult Lead Poisoning From A Herbal Medicine, Abdulsalam S. Ibrahim, Ali H. Latif May 2002

Adult Lead Poisoning From A Herbal Medicine, Abdulsalam S. Ibrahim, Ali H. Latif

Saudi Medical Journal

A 56-year-old Indian lady presented with one week history of abdominal pain, jaundice and chronic polyarthralgia. She had evidence of hemolytic anemia and hepatitis. Her blood lead level was high and a peripheral blood film showed dense basophilic stippling. It is believed that the lead toxicity was due to the use of Indian herbal medicine.


The Effect Of Magneto-Treated Blood Autotransfusion On Central Hemodynamic Values And Cerebral Circulation In Patients With Essential Hypertension, Ilgar G. Alizade, Nigar T. Karayeva May 2002

The Effect Of Magneto-Treated Blood Autotransfusion On Central Hemodynamic Values And Cerebral Circulation In Patients With Essential Hypertension, Ilgar G. Alizade, Nigar T. Karayeva

Saudi Medical Journal

OBJECTIVE: The work was carried out to study the effect of magneto-treated blood autotransfusion on the values of central and cerebral hemodynamics in patients with essential hypertension. METHODS: Sixty-six patients with stage II essential hypertension aged 31-60 years who underwent magneto-treated blood autotransfusion were evaluated and treated, at the Cardiology Department, Hospital of Ministry of Internal Affairs of the Azerbaijan Republic, over a period of 8 years. The diagnosis was based on clinical examination and generally accepted criteria of essential hypertension stages proposed in 1978 by the World Health Organization. RESULTS: Sixty-six patients with stage II essential hypertension with stable …


Efficacy And Tolerability Of Valsartan In Patients With Mild To Moderate Essential Hypertension, Mohamed S. Nouh, Samy A. Halim May 2002

Efficacy And Tolerability Of Valsartan In Patients With Mild To Moderate Essential Hypertension, Mohamed S. Nouh, Samy A. Halim

Saudi Medical Journal

OBJECTIVE: To assess the efficacy of valsartan in a different ethnic population than that studied in international trials. Also to compare the adverse experiences reported in this trial with those reported internationally. METHODS: A total of 2940 patients with newly diagnosed or established uncomplicated mild-to-moderate essential hypertension participated in this open-label study. Each participating investigator was asked to enrol 12 patients, 10 on valsartan and 2, serving as controls, on any other anti-hypertensive. The control group included patients of similar clinical setting, disease severity, and overall health profile using alternative anti-hypertensive treatments was enrolled for tracking of patients receiving any …


Copper, Zinc And Magnesium Levels In Type-1 Diabetes Mellitus, Abdul H. Zargar, Mir I. Bashir, Shariq R. Masoodi, Bashir A. Laway, Arshad I. Wani, Abdul R. Khan, Farooq A. Dar May 2002

Copper, Zinc And Magnesium Levels In Type-1 Diabetes Mellitus, Abdul H. Zargar, Mir I. Bashir, Shariq R. Masoodi, Bashir A. Laway, Arshad I. Wani, Abdul R. Khan, Farooq A. Dar

Saudi Medical Journal

OBJECTIVE: Alterations in plasma concentrations of several trace elements have been reported to occur in type-1 diabetes mellitus. These micronutrients are suspected to have a role in pathogenesis and progression of the disease. METHODS: In a comparative analysis, the plasma concentration of copper, zinc and magnesium was estimated in 37 patients with type-1 diabetes mellitus and 25 healthy non-diabetic subjects at Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Kashmir, India. Trace elements were estimated using a GBC 902 double beam atomic absorption spectrophotometer. RESULTS: Mean plasma concentrations of copper and magnesium were comparable between diabetic patients and control subjects. Plasma zinc …


Frequency Of Neutrophil Alloantigens By Polymerase Chain Reaction, Iman H. Al-Sheikh, Mohammed A. Al-Khalifa, Amjad S. Rahi May 2002

Frequency Of Neutrophil Alloantigens By Polymerase Chain Reaction, Iman H. Al-Sheikh, Mohammed A. Al-Khalifa, Amjad S. Rahi

Saudi Medical Journal

OBJECTIVE: Neutrophil alloantigens are responsible for a number of immune clinical disorders such as neonatal alloimmune neutropenia, febrile transfusion reaction and transfusion related acute lung injury. Recent progress enabled typing of neutrophil antigens by deoxyribose nucleic acid based techniques. In this study we report for the first time the frequency distribution of human neutrophil antigen system-one in Saudis. METHODS: Blood samples were collected from 100 successive healthy Saudi male blood donors presenting to Regional Laboratory and Blood Bank, Dammam, Kingdom of Saudi Arabia in 1997. Human neutrophil antigen typing was carried out using polymerase chain reaction-sequence specific primer method. RESULTS: …


Current Trends In Hormone Replacement Therapy, Tariq Y. Khashoggi May 2002

Current Trends In Hormone Replacement Therapy, Tariq Y. Khashoggi

Saudi Medical Journal

As life span increases, more and more women live longer after the menopause, and see its long-term consequences. The menopause and climacteric have major consequences for the well being of most women, resulting in a variety of symptoms including vasomotor, psychological, sexual symptoms and increased risk of osteoporosis and atherosclerosis. Prevention of osteoporosis and reduction in cardiovascular risks are the long-term goals of post-menopausal hormone replacement therapy. Post-menopausal women who receive hormone replacement therapy have approximately half of the rate of coronary artery disease compared to those who do not take it. Similarly, estrogen replacement alone for 5 years results …


Extrapulmonary Tuberculosis, Epidemiology And Patterns In Saudi Arabia, Abdulrahman A. Alrajhi, Ali M. Al-Barrak May 2002

Extrapulmonary Tuberculosis, Epidemiology And Patterns In Saudi Arabia, Abdulrahman A. Alrajhi, Ali M. Al-Barrak

Saudi Medical Journal

Annual incidence rates of extrapulmonary tuberculosis have been increasing over the last few years in the Kingdom of Saudi Arabia. True rates may even be higher due to incomplete reporting. Diagnosis of this condition requires high clinical suspicion, special diagnostic procedures, special staining, and culture media for acid fast bacilli. Delayed diagnosis results in increasing morbidity, mortality, and cost to the health care system. Particularly in areas of high endemicity of Mycobacterium tuberculosis, clinicians should be aware of the various forms of extrapulmonary tuberculosis. The available epidemiology and patterns of various forms of extrapulmonary tuberculosis in the Kingdom of Saudi …


The Status Of Cadaveric Organ Donation For Liver Transplantation In Saudi Arabia, Mohammed I. Al-Sebayel May 2002

The Status Of Cadaveric Organ Donation For Liver Transplantation In Saudi Arabia, Mohammed I. Al-Sebayel

Saudi Medical Journal

OBJECTIVE: Over the past 2 decades, liver transplantation has became the standard treatment of end stage liver disease. Organ shortage has been the main hindrance against the progress of liver transplantation in the Kingdom of Saudi Arabia. This paper reports the status of organ donation for liver transplantation in the Kingdom of Saudi Arabia and highlights the problems and the suggested solutions in relation to organ shortage. METHODS: All donors reported to the liver transplant program at the King Fahad National Guard Hospital, Riyadh, Kingdom of Saudi Arabia, from the Saudi Center of Organ Transplantation from January 1994 through to …