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Relaxation Therapy In The Background Of Standard Antihypertensive Drug Treatment Is Effective In Management Of Moderate To Severe Essential Hypertension, Fatemeh Ranjbar, Fariborz Akbarzadeh, Kazemi Kazemi, Abdolrasoul Safaeiyan
Relaxation Therapy In The Background Of Standard Antihypertensive Drug Treatment Is Effective In Management Of Moderate To Severe Essential Hypertension, Fatemeh Ranjbar, Fariborz Akbarzadeh, Kazemi Kazemi, Abdolrasoul Safaeiyan
Saudi Medical Journal
OBJECTIVE: To evaluate the efficacy of relaxation technique as an adjunctive therapy for control of hypertension. METHODS: From April 2004 to January 2005, with a single blinded randomized controlled design, 220 patients with newly diagnosed essential moderate to severe hypertension who needed drug therapy were included in the study. The study took place in the Hypertension Clinic, Sina Hospital, Tabriz, Iran. Patients were systematically randomized to receive standard plus relaxation therapy, 2 times per week, for 8 weeks, or standard therapy alone. We collected the demographic data, blood pressure measurements, and the data on prescribed drugs. RESULTS: The mean age …
Antibacterial Activity Of Eurycoma Longifolia Jack. A Malaysian Medicinal Plant, Abd-Elaziem Farouk, Asma Benafri
Antibacterial Activity Of Eurycoma Longifolia Jack. A Malaysian Medicinal Plant, Abd-Elaziem Farouk, Asma Benafri
Saudi Medical Journal
OBJECTIVE: To evaluate methanolic, ethanolic, acetone and aqueous extracts from different parts of Eurycoma longifolia (E. longifolia) (leave, stem, and root) for antibacterial activity against Gram-positive and Gram-negative bacteria and to utilize the leaves and stem parts rather than the root, which is already used for male sexual enhancement in Malaysia. METHODS: The study took place in the Laboratory of Molecular Biology of Biotechnology Engineering Department, Malaysia between January 2005 and June 2006. Methanolic, ethanolic, acetone and aqueous extracts of leaves, stems and roots of E. longifolia were investigated for their antibacterial properties using Agar-well diffusion method. RESULTS: The alcoholic …
Pre-Hospital Period In Patients With Myocardial Infarction In Turkey. Methodological And Statistical Pitfalls, Mustafa M. Afifi
Pre-Hospital Period In Patients With Myocardial Infarction In Turkey. Methodological And Statistical Pitfalls, Mustafa M. Afifi
Saudi Medical Journal
No abstract provided.
The Gulf Cooperation Countries Genetic Services. Understanding Individuals, Families, And Community Needs, Anna A. Rajab, Mohsen Af El-Hazmi
The Gulf Cooperation Countries Genetic Services. Understanding Individuals, Families, And Community Needs, Anna A. Rajab, Mohsen Af El-Hazmi
Saudi Medical Journal
No abstract provided.
Updated Overview Of Pediatric Headache And Migraine, Mohammed M. Jan
Updated Overview Of Pediatric Headache And Migraine, Mohammed M. Jan
Saudi Medical Journal
Headache is a common complaint, occurring in >90% of school age children. The frequency increases with increasing age and the etiologies range from tension to life-threatening infections and brain tumors. Migraine is the most frequent cause of acute and recurrent headaches in children. The overall prevalence of non-migraine headaches is 10-25%. A thorough history, physical and neurological examination, and appropriate diagnostic testing if indicated will enable the physician to distinguish migraine and tension headaches from those of a secondary etiology. In this review, we present an updated overview of childhood headaches. The recently developed International Classification of Headache Disorders, second …
Current Treatment Strategy For Hepatocellular Carcinoma, Kelvin K. Ng, Ronnie T. Poon
Current Treatment Strategy For Hepatocellular Carcinoma, Kelvin K. Ng, Ronnie T. Poon
Saudi Medical Journal
With the current practice of surveillance programs in high-risk patients, early stage hepatocellular carcinoma HCC is commonly diagnosed. This poses great challenge to clinicians, in terms of prognostic estimation, patient stratification to various treatment modalities and patient management during long-term follow-up. This review focuses on the current trends in the management of HCC, with special attention to tumor staging, treatment algorithm, and outcome of various treatment modalities. According to the American Association for the Study of Liver Diseases AASLD practice guideline, Barcelona Clinic Liver Cancer BCLC staging system has fulfilled the criteria that HCC patients can be stratified into different …
Intraventricular Hemorrhage In Very Low Birth Weight Infants. Associated Risk Factors In Isfahan, Iran, Zohreh Badiee
Intraventricular Hemorrhage In Very Low Birth Weight Infants. Associated Risk Factors In Isfahan, Iran, Zohreh Badiee
Saudi Medical Journal
OBJECTIVE: Prematurely born infants with intraventricular hemorrhage (IVH) suffer significant morbidity and mortality, particularly those infants with high-grade hemorrhage. Previous studies have proposed a number of risk factors for IVH; however, lack of adequate matching for gestational age and birth weight may have confounded the results. The purpose of this study was to identify variables that affect the risk of IVH. METHODS: We identified 31 preterm infants with gestational age <32 weeks and birth weight <1500 g, with IVH, from November 2003 to January 2005 at Alzahra University Hospital, Isfahan, Iran. A control group of 90 infants, matched for gestational age and birth weight was selected. Maternal factors, labor and delivery characteristics and neonatal parameters were colleted in both groups. Results of cranial ultrasound examinations were also collected. RESULTS: The significant risk factors for IVH were found to be: patent ductus arteriosus (PDA) [4 (13.3%) versus 3 (3.3%) (p=0.01)], longer duration of assisted ventilation [2.8 ± 5.8 days versus 0.5 ± 2.1 days (p=0.002)], higher number of endotracheal suctioning [9.7 ± 18.4 versus 3.06 ± 13.7 (p=0.004)], surfactant use, [7 (22.6%) versus 3 (3.4%) (p=0.003)], positive pressure ventilation at birth [(12 (38.7%) versus 12 (13.3%), (p=0.004)] and low Apgar score at 1 and 5 minutes. Whereas antenatal steroid treatments and cesarean section have a protective effect on the occurrence of IVH. CONCLUSION: Our data emphasize the importance of obstetric and perinatal care to improve outcomes of premature infants.
A Prospective Study Of Congenital Malformations Among Live Born Neonates At A University Hospital In Western Saudi Arabia, Nadia M. Fida, Jumana Al-Aama, Wafaa Nichols, Wafaa Nichols, Mohamed Alqahtani
A Prospective Study Of Congenital Malformations Among Live Born Neonates At A University Hospital In Western Saudi Arabia, Nadia M. Fida, Jumana Al-Aama, Wafaa Nichols, Wafaa Nichols, Mohamed Alqahtani
Saudi Medical Journal
OBJECTIVE: To estimate the incidence of major and minor congenital malformations among liveborn infants at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. Estimation of risk factors were also evaluated. METHODS: Between March 2004 and May 2005, a total of 5356 babies born at King Abdulaziz University Hospital, were enrolled in this study for malformations. Details of cases were recorded after parents9 interviews, clinical, radiological, and laboratory evaluations. RESULTS: One hundred and forty-seven (27.06/1000 livebirth) and 13 (2.39/1000 birth) stillbirth had congenital anomalies. In all livebirth, incidences of major anomalies were 93.9% and minor were 6.1%. Mothers of 95.9% with congenital …
Impact Of C-Erb2 Status On Survival After High Dose Chemotherapy In High-Risk Breast Cancer Patients, Okan Kuzhan, Ahmet Ozet, Cuneyt Ulutin, Bulent Kurt, Seref Komurcu, Bekir Ozturk, Selmin Ataergin, Omer Gunhan
Impact Of C-Erb2 Status On Survival After High Dose Chemotherapy In High-Risk Breast Cancer Patients, Okan Kuzhan, Ahmet Ozet, Cuneyt Ulutin, Bulent Kurt, Seref Komurcu, Bekir Ozturk, Selmin Ataergin, Omer Gunhan
Saudi Medical Journal
OBJECTIVE: To investigate the impact of c-erb2 status on survival after high-dose chemotherapy. METHODS: Between March 1997 and June 2004, a total of 54 women with breast cancer who has at least 8 metastatic lymph nodes underwent high-dose chemotherapy with hematopoietic stem cell transplantation in Gulhane Military Medical School, Ankara, Turkey. Archival specimens were analyzed by fluorescent in situ hybridization to determine the impact of c-erb2 status after peripheral blood stem cell transplantation on survival. The patients were divided into c-erb2 negative (n=20) and positive (n=11) groups. RESULTS: No statistically significant differences were detected between c-erb2 negative and positive groups …
Risk Factors Identification For Ocular Trauma In Patients Who Presented In A Suburban Tertiary Care Hospital In Nigeria, Malachi E. Enock, Afekhide E. Omoti, Anita A. Alikah
Risk Factors Identification For Ocular Trauma In Patients Who Presented In A Suburban Tertiary Care Hospital In Nigeria, Malachi E. Enock, Afekhide E. Omoti, Anita A. Alikah
Saudi Medical Journal
OBJECTIVE: To determine the risk factors, and the pattern of ocular trauma in Irrua, a sub-urban community in Edo State, Nigeria. METHODS: A prospective study of all cases of ocular trauma seen in the Irrua Specialist Teaching Hospital, Irrua, Nigeria from January to December 2005. The age, gender, occupation, activity at time of injury, use of protective eye wear, visual acuity, and findings on ocular examination were recorded. RESULTS: One hundred and eighty-two patients were seen during the period of study. There were 130 males (72.2%) and 52 females (28.8%), with a ratio of 2.5:1. Motorcycle-related road traffic accident was …
Assessment Of Quality Of Life In Saudi Patients With Vitiligo In A Medical School In Qassim Province, Saudi Arabia
Saudi Medical Journal
OBJECTIVE: To determine the quality of life in Saudi patients with vitiligo and to detect the variables that could influence it by using the Dermatology Life Quality Index (DLQI). METHODS: One hundred and nine Saudi vitiligo patients were recruited from Qassim Medical College clinics between November 2004 and September 2006. We included 61 males, 48 females with an age range of 18 to 47 years, and a mean of 26.94 (SD ± 9.73) years. Quality of life was evaluated using DLQI questionnaire and related to variables as age, gender, marital status, and extent of cutaneous involvement. RESULTS: Family history of …
Bone Metabolism And Mineral Density In Patients With Beta-Thalassemia Major, Umit Dundar, Alphan Kupesiz, Sebahat Ozdem, Erdal Gilgil, Tiraje Tuncer, Akif Yesilipek, Meral Gultekin
Bone Metabolism And Mineral Density In Patients With Beta-Thalassemia Major, Umit Dundar, Alphan Kupesiz, Sebahat Ozdem, Erdal Gilgil, Tiraje Tuncer, Akif Yesilipek, Meral Gultekin
Saudi Medical Journal
OBJECTIVE: To evaluate bone metabolism in patients with beta-thalassemia major and to determine the factors associated with the development of osteoporosis. METHODS: We studied 25 patients with thalassemia major with a mean age of 18.4 years (range 5-31) and aged and gender matched 24 healthy controls who were attending the outpatient physical medicine and rehabilitation clinic of Akdeniz University Hospital between January 2004 and March 2004 in Turkey. Bone mineral density (BMD) of lumbar spine (L1-L4) and proximal femur were determined using dual x-ray absorptiometry (DXA). Venous blood samples were obtained for determination of blood cell count and markers of …
The Knowledge And Attitudes Of The Primary Care Physicians On Developmental Dysplasia Of The Hip, Murat Uzel, Guney U. Ergun, Hasan C. Ekerbicer
The Knowledge And Attitudes Of The Primary Care Physicians On Developmental Dysplasia Of The Hip, Murat Uzel, Guney U. Ergun, Hasan C. Ekerbicer
Saudi Medical Journal
OBJECTIVE: For the prevention and early diagnosis of developmental dysplasia of the hip (DDH), a detailed clinical screening of the newborn performed by a primary care (PC) physician is recommended as a standard practice throughout the most western countries. We aimed to determine the knowledge and attitudes of the PC physicians towards DDH, and to develop further educational and training programs, according to the results obtained from the study. METHODS: The study was a pre- and post- test with a cross-sectional design. In winter of 2005, the participants included 102 PC physicians from 20 primary health care centers in Kahramanmaras, …
Dracunculiasis. An Incidental Diagnosis In A Saudi Female, Fayaz A. Hakim, Nadra N. Khan
Dracunculiasis. An Incidental Diagnosis In A Saudi Female, Fayaz A. Hakim, Nadra N. Khan
Saudi Medical Journal
Dracunculiasis is a disabling, and economically crippling parasitic infestation transmitted by drinking contaminated water. Although the disease has been eradicated from most parts of the world, it is still endemic in some tropical African countries. Here we report a 65-year-old female from the southern region of Saudi Arabia with radiological evidence of heavy load of guinea worms. This case could represent the local reemergence of the disease.
Isolated Nail Lichen Planus With Primary Sclerosing Cholangitis In A Child, Nejoud Al-Ajroush, Sultan Al-Khenaizan
Isolated Nail Lichen Planus With Primary Sclerosing Cholangitis In A Child, Nejoud Al-Ajroush, Sultan Al-Khenaizan
Saudi Medical Journal
Lichen planus LP is an uncommon, inflammatory dermatosis with characteristic lesions affecting the skin, the nails, and the mucous membranes. It is rare in childhood. Although nail abnormalities have been reported in 1 - 10% of patients with LP, the prevalence of nail involvement in affected children is unknown. Here we report a 2-year-old child with isolated nail LP, in association with primary sclerosing cholangitis.
Fucosidosis And Anesthesia, Alireza E. Soltani, Reza S. Moharari, Reza Ghaffari, Hamid Zahedi, Mojgan Hajmahmoodi
Fucosidosis And Anesthesia, Alireza E. Soltani, Reza S. Moharari, Reza Ghaffari, Hamid Zahedi, Mojgan Hajmahmoodi
Saudi Medical Journal
Fucosidosis is a rare, autosomal recessive lysosomal storage disorder caused by a severe deficiency of a-L-fucosidase. Patients usually have some problems with glycoprotein storage in the brain and other organs, and some structural abnormalities that need special consideration in anesthesia. It has 2 types, the early onset or infantile, and the juvenile. Here we present an 8-year old girl with deformities in the maxillofacial region, with big tongue, small and retracted chin, saddle nose, and short neck that could not be extended, causing difficult intubation, and congenital cardiac problems requiring a special anesthetic strategy.
Terminal Ileum Schistosomiasis With Perianal Fistula Mimicking Crohn's Disease, Mohammad A. Sheikh, Sohail A. Ashraf
Terminal Ileum Schistosomiasis With Perianal Fistula Mimicking Crohn's Disease, Mohammad A. Sheikh, Sohail A. Ashraf
Saudi Medical Journal
Schistosomiasis is a parasitic disease related to water contact in the agricultural fields, affecting millions of people in developing countries in tropical and subtropical parts of Africa, Asia, and South America. We report a case of a 27-year-old male, with intestinal schistosomiasis associated with perianal fistula mimicking Crohn9s disease, where the terminal ileum showed a cobblestone appearance, and histopathological biopsy showed schistosoma granuloma.
Effects Of Pharmacological Concentration Of Melatonin On Reperfusion Injury In Rats, Ayse S. Ilhan, Eser O. Oyar, Deniz Erbas, Ozlem Sivasli
Effects Of Pharmacological Concentration Of Melatonin On Reperfusion Injury In Rats, Ayse S. Ilhan, Eser O. Oyar, Deniz Erbas, Ozlem Sivasli
Saudi Medical Journal
No abstract provided.
A Comparison Of Sensitivities Of The Conventional And The Real-Time Polymerase Chain Reaction Methods For Detection Of Treponema Denticola In Periapical Abscesses, Ahmet Ozbek, Selcuk M. Ozbek, Elvan Ozbek
A Comparison Of Sensitivities Of The Conventional And The Real-Time Polymerase Chain Reaction Methods For Detection Of Treponema Denticola In Periapical Abscesses, Ahmet Ozbek, Selcuk M. Ozbek, Elvan Ozbek
Saudi Medical Journal
No abstract provided.
Motor Vehicle Accidents During Pregnancy. A Review Of Maternal And Fetal Outcomes In Saudi Arabian Population, Hayfaa A. Wahabi, Ahmed T. Saleh, Abdelmonim A. Abdelrahman
Motor Vehicle Accidents During Pregnancy. A Review Of Maternal And Fetal Outcomes In Saudi Arabian Population, Hayfaa A. Wahabi, Ahmed T. Saleh, Abdelmonim A. Abdelrahman
Saudi Medical Journal
No abstract provided.
Epidemiology Of Atrial Fibrillation Among Qatari Patients Admitted With Various Cardiovascular Disorder. A Population-Based Study, Wafer A. Dabdoob, Abdulbari Bener, Dhabia Al-Mohannadi, Mohammad T. Numan, Hajar A. Al-Binali, Jassim Al-Suwaidi
Epidemiology Of Atrial Fibrillation Among Qatari Patients Admitted With Various Cardiovascular Disorder. A Population-Based Study, Wafer A. Dabdoob, Abdulbari Bener, Dhabia Al-Mohannadi, Mohammad T. Numan, Hajar A. Al-Binali, Jassim Al-Suwaidi
Saudi Medical Journal
No abstract provided.
Reducing The Medical Costs Of Urinary Tract Infections Investigation In Infants, Christos N. Karakos, Konstantinos N. Stamatiou
Reducing The Medical Costs Of Urinary Tract Infections Investigation In Infants, Christos N. Karakos, Konstantinos N. Stamatiou
Saudi Medical Journal
No abstract provided.
Effect Of Androgens On Bone Mineral Density In Saudi Arabian Males Above The Age Of 50 Years, Mir Sadat-Ali, Abdulmohsen H. Alelq
Effect Of Androgens On Bone Mineral Density In Saudi Arabian Males Above The Age Of 50 Years, Mir Sadat-Ali, Abdulmohsen H. Alelq
Saudi Medical Journal
OBJECTIVE: To test the effect of sex steroids on the development of osteoporosis in male Saudi Arabs above the age of 50 years. METHODS: Male Saudi patients over the age of 50 years, attending the outpatient clinics between May 2005 and January 2006 of King Fahd Hospital of the University, Al-Khobar, Kingdom of Saudi Arabia, comprised the study subjects. Patient9s body mass index was calculated, and investigations were performed to rule out secondary osteoporosis. Blood was extracted for serum level of androgens, gonadotropins, and thyroid stimulating hormone, albumin, calcium, phosphorus, and alkaline phosphatase. Bone mineral density measurement of hip and …
Actual Antibiotic Resistance Pattern Of Brucella Melitensis In Central Anatolia. An Update From An Endemic Region, Esra Tanyel, Ahmet Y. Coban, Suda T. Koruk, Husniye Simsek, Serkan Hepsert, Osman S. Cirit, Necla Tulek
Actual Antibiotic Resistance Pattern Of Brucella Melitensis In Central Anatolia. An Update From An Endemic Region, Esra Tanyel, Ahmet Y. Coban, Suda T. Koruk, Husniye Simsek, Serkan Hepsert, Osman S. Cirit, Necla Tulek
Saudi Medical Journal
OBJECTIVE: To test in vitro susceptibilities of Brucella melitensis (B. melitensis) blood isolates obtained from an endemic region, by broth microdilution susceptibility test. METHODS: Fifty blood isolates were tested with anti-brucella antibiotics, namely, tetracycline, gentamicin, streptomycin, ceftriaxone, ciprofloxacin, levofloxacin, ofloxacin, and rifampin. All of the clinical isolates belonged to the group of B. melitensis biotype-3. This study was performed at the Clinical Microbiology Laboratory of the Medical School of Ondokuz Mayis University, Samsun, Turkey, in 2005. RESULTS: In terms of minimum inhibitory concentration-90 (MIC90) values, tetracycline (MIC90 0.25 microgram/mL) and rifampin (MIC90 0.5 microgram/mL) still continue to be the most …
Mobile Phone Induced Sensorineural Hearing Loss, Surayie H. Al-Dousary
Mobile Phone Induced Sensorineural Hearing Loss, Surayie H. Al-Dousary
Saudi Medical Journal
The increased use of mobile phones worldwide has focused interest on the biological effects and possible health outcomes of exposure to radiofrequency fields from mobile phones, and their base stations. Various reports suggest that mobile phone use can cause health problems like fatigue, headache, dizziness, tension, and sleep disturbances; however, only limited research data is available in medical literature regarding interaction between electromagnetic fields emitted by mobile phones and auditory function; and the possible impact on hearing. We report a case of sensorineural hearing loss due to Global System for Mobile Communications mobile phone use, in a 42-year-old male.
Assessment Of Nutritional Status And Lifestyle Pattern Among Saudi Arabian School Children, Fayssal M. Farahat, Kamlesh P. Joshi, Falah F. Al-Mazrou
Assessment Of Nutritional Status And Lifestyle Pattern Among Saudi Arabian School Children, Fayssal M. Farahat, Kamlesh P. Joshi, Falah F. Al-Mazrou
Saudi Medical Journal
No abstract provided.
Autologous Chondrocyte Implantation For The Treatment Of Large Full-Thickness Cartilage Lesions Of The Knee, Christian Ossendorf, Peter C. Kreuz, Matthias R. Steinwachs, Christoph Erggelet
Autologous Chondrocyte Implantation For The Treatment Of Large Full-Thickness Cartilage Lesions Of The Knee, Christian Ossendorf, Peter C. Kreuz, Matthias R. Steinwachs, Christoph Erggelet
Saudi Medical Journal
OBJECTIVE: To investigate the benefit, reliability, and complication rate of autologous chondrocyte implantation (ACI) in patients with large full-thickness cartilage defects of the knee. METHODS: Between March 1997 and December 2001, 71 consecutive patients (24 women, 47 men) were treated with ACI at the Freiburg University Hospital, Germany, and were included in this study. Average age was 35 years (13-61). Lesions were mainly situated on the medial femoral condyle (n=46); mean defects size was 6.61 cm2 (2-17.5), outerbridge grade III-IV. Number of previous surgical procedures was 2.13 (0-8). For outcome measurement, International Cartilage Repair Society (ICRS) knee examination form, Lysholm …
The Study Of Diabetes Mellitus In Gorgan, Iran, Gholamreza Veghari, Abdoljalal Marjani, Hamidreza Joshaghani
The Study Of Diabetes Mellitus In Gorgan, Iran, Gholamreza Veghari, Abdoljalal Marjani, Hamidreza Joshaghani
Saudi Medical Journal
No abstract provided.
Saudi Newborn Screening. A National Public Health Program: Needs, Costs, And Challenges, Ashraf M. Afifi, Mohammad A. Abdul-Jabbar
Saudi Newborn Screening. A National Public Health Program: Needs, Costs, And Challenges, Ashraf M. Afifi, Mohammad A. Abdul-Jabbar
Saudi Medical Journal
A Saudi newborn screening program is important to the half million Saudi children born each year in the Kingdom of Saudi Arabia. It is a coordinated and comprehensive system consisting of education, screening, diagnosis, treatment and management, follow-up, and program evaluation. The Saudi newborn population should benefit from this program and affected infants will be diagnosed early, and managed effectively. Both cost effectiveness, and cost benefit justifications are presented. Funding for the program can be a public health challenge. We offered recommendations to achieve this vital program.
The Potential Osteogenic Effects Of Systemic Leptin And Insulin Administration In Streptozotocin-Induced Diabetic Female Rats, Hayam I. Gad
The Potential Osteogenic Effects Of Systemic Leptin And Insulin Administration In Streptozotocin-Induced Diabetic Female Rats, Hayam I. Gad
Saudi Medical Journal
OBJECTIVE: To evaluate the effect of leptin administration on some biochemical parameters of bone turnover in diabetic rats using either leptin alone or a combination of leptin and insulin. METHODS: The study was carried out on 32 female Wistar rats supplied by the Medical College animal house at King Khalid Hospital, Riyadh, Kingdom of Saudi Arabia during the period from March to December 2006. Rats were divided into 4 groups (8 rats each), controls, non-treated diabetic, leptin-treated diabetic, and leptin plus insulin-treated diabetic rats. After induction of diabetes by 6 weeks, treatment with leptin either alone or combined with insulin …