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Immature Reticulocyte Fraction Is An Early Predictor Of Bone Marrow Recovery Post Chemotherapy In Patients With Acute Leukemia, Rajazahratul A. Raja-Sabudin, Ainoon Othman, Khalidawad E. Ahmed-Mohamed, Azlin Ithnin, Hafiza Alauddin, Hamidah Alias, Zarina Abdul-Latif, Srijit Das, Fadilah S. Abdul-Wahid, Noor H. Hussin Apr 2014

Immature Reticulocyte Fraction Is An Early Predictor Of Bone Marrow Recovery Post Chemotherapy In Patients With Acute Leukemia, Rajazahratul A. Raja-Sabudin, Ainoon Othman, Khalidawad E. Ahmed-Mohamed, Azlin Ithnin, Hafiza Alauddin, Hamidah Alias, Zarina Abdul-Latif, Srijit Das, Fadilah S. Abdul-Wahid, Noor H. Hussin

Saudi Medical Journal

OBJECTIVE: To establish the benefits of immature reticulocyte fraction (IRF) measurement using an automated hematology cells analyzer over absolute neutrophil count (ANC) in predicting bone marrow recovery post induction chemotherapy. METHODS: A prospective observational study was carried out in the Departments of Pathology, Medicine, and Pediatrics, Universiti Kebangsaan Malaysia, Medical Center (UKMMC), Kuala Lumpur, Malaysia during a period of 19 months from April 2009 to December 2010 to assess the bone marrow recovery in patients with acute leukemia. A total of 22 patients in remission induction phases were enrolled in this study. The blood specimens were collected from day zero …


Seroprevalence, Transmission, And Associated Factors Of Specific Antibodies Against Cytomegalovirus Among Pregnant Women And Their Infants In A Regional Study, Mahmood Erfanianahmadpoor, Roya Nasiri, Rosita Vakili, Tahereh Hassannia Apr 2014

Seroprevalence, Transmission, And Associated Factors Of Specific Antibodies Against Cytomegalovirus Among Pregnant Women And Their Infants In A Regional Study, Mahmood Erfanianahmadpoor, Roya Nasiri, Rosita Vakili, Tahereh Hassannia

Saudi Medical Journal

OBJECTIVE: To assess specific anti-cytomegalovirus (CMV) antibodies, clinical status, and demographic data in pregnant women and their infants in northeast Iran. METHODS: This cross-sectional study was conducted on 225 systematic randomly selected-pregnant women and their newborns attending public hospitals in Mashhad, Iran between December 2007 and January 2008. Two specialists performed clinical assessment and obtained the demographic data. The sera from mothers and the umbilical cord of infants were then collected at the time of delivery and anti-CMV antibodies, IgG, and IgM, were measured. RESULTS: Although, all mothers and their neonates were positive for anti-CMV IgG (100%), only 6 were …


Assessment Of Trace Elements In Sera Of Patients Undergoing Renal Dialysis, Rana M. Hasanato Apr 2014

Assessment Of Trace Elements In Sera Of Patients Undergoing Renal Dialysis, Rana M. Hasanato

Saudi Medical Journal

OBJECTIVE: To assess the serum levels of copper, zinc, iron, and lead in patients on maintenance dialysis. METHODS: This cross-sectional study performed at King Khalid University Hospital, Riyadh, Saudi Arabia between September 2011 and October 2012 included 42 patients with end stage renal disease on hemodialysis (HD), 18 patients on peritoneal dialysis (PD), and 18 normal controls. Serum copper, zinc, and lead levels were determined by atomic absorption spectrophotometry, and serum iron was determined by spectrophotometric determination. RESULTS: The median serum copper level in HD patients (20.5 nmol/L; 95% confidence interval [CI]: 17.52-22.39; interquartile range [IQR]: 16.40-24.20) was higher (p=0.001) …


Ocular Malignant Tumors. Review Of The Tumor Registry At A Tertiary Eye Hospital In Central Saudi Arabia, Rajiv B. Khandekar, Abdulelah A. Al-Towerki, Hind Al-Katan, Saleh S. Al-Mesfer, Emad B. Abboud, Hailah M. Al-Hussain, Osama H. Sheikh, Imtiaz A. Chaudhry, Wafa A. Ahmed, Babar M. Zaman, Nasira Asghar, Deepak P. Edward Apr 2014

Ocular Malignant Tumors. Review Of The Tumor Registry At A Tertiary Eye Hospital In Central Saudi Arabia, Rajiv B. Khandekar, Abdulelah A. Al-Towerki, Hind Al-Katan, Saleh S. Al-Mesfer, Emad B. Abboud, Hailah M. Al-Hussain, Osama H. Sheikh, Imtiaz A. Chaudhry, Wafa A. Ahmed, Babar M. Zaman, Nasira Asghar, Deepak P. Edward

Saudi Medical Journal

OBJECTIVE: To present the epidemiologic profile and magnitude of ocular malignant tumors (MT) representative of the Saudi population from the Tumor Registry (TR) at King Khaled Eye Specialist Hospital (KKESH). METHODS: This study evaluated the demographic information, clinical features including tumor laterality, ocular tissue of origin, and diagnosis of patients from the TR registry between 1983 and 2012 at KKESH, Riyadh, Kingdom of Saudi Arabia. The incidence of MT among Saudi adults (>/= 15 years old), and children (<15 years old) was estimated. RESULTS: The TR recorded 4,146 neoplasms (2,509 [60.5%] benign tumors, and 1,637 [39.5%] MT). The incidence of MT in children was 3.6 per million/year (M/Y), and 2.4/M/Y for adults. Retinoblastoma (Rb) (n=763, 91%) was the most common ocular malignancy in children. In adults, the most common MT was squamous cell carcinoma (SCC) (n=363, 45.8%), basal cell carcinoma (BCC) (n=186, 23%), uvealmelanoma (n=94, 11.9%), sebaceous gland carcinoma (n=54, 6.8%), lymphomas (orbital, adnexal) (n=46, 5.8%), and others (n=53, 6.8%). The Rb (7.7/M/Y in <5 years old Saudi children) was less frequent than that reported in some Gulf countries, but higher than that reported from the West. The SCC was less frequent in countries with comparable sun exposure than in other continents, but the incidence remained unchanged over 3 decades. There was a significant increase in BCC between 1983-1992 and 2003-2012. CONCLUSION: The rates of all cancers remained stable over 3 decades except BCC, which showed a significant rise.


Early Results Of The Proximal Femoral Nail Antirotation-Asia For Intertrochanteric Fractures In Elderly Chinese Patients, Jun Li, Xin-Zhong Xu, Tao You, Hu Li, Jue-Hua Jing Apr 2014

Early Results Of The Proximal Femoral Nail Antirotation-Asia For Intertrochanteric Fractures In Elderly Chinese Patients, Jun Li, Xin-Zhong Xu, Tao You, Hu Li, Jue-Hua Jing

Saudi Medical Journal

OBJECTIVE: To report early efficacy and safety of the proximal femoral nail antirotation-Asia for intertrochanteric fractures in elderly Chinese patients. METHODS: This retrospective study was carried out in the Second Hospital of Anhui Medical University, Anhui, China between June 2009 and December 2012. A total of 108 patients with intertrochanteric fractures were available for the outcome analysis in the study. There were 62 female and 46 male patients with a mean age of 75 +/= 10 years. The stable group included 18 cases of 31 A1 fractures, the unstable group included 68 cases of 31 A2 fractures, and 22 cases …


Impact Of Atopic Dermatitis On The Quality Of Life Of Saudi Children, Abdullateef A. Alzolibani Apr 2014

Impact Of Atopic Dermatitis On The Quality Of Life Of Saudi Children, Abdullateef A. Alzolibani

Saudi Medical Journal

OBJECTIVE: To assess the impact of atopic dermatitis (AD) on the quality of life (QoL) of Saudi infants and children using a validated/culturally adapted Arabic version of the infants’ dermatitis quality of life (IDQoL) index, and to investigate the correlation between IDQoL and disease severity. METHODS: This study was performed in the Dermatology Clinics and Hospitals affiliated to Qassim University, Buraidah, Saudi Arabia between September 2012 and August 2013. The study was designed to investigate the role of IDQoL in AD patients with different severities. The AD patients (n=630) were evaluated for IDQoL and disease severity using the SCORing of …


Idiopathic Hemihypertrophy, Mabrook A. Mohanna, Abdulkhalig Sallam Apr 2014

Idiopathic Hemihypertrophy, Mabrook A. Mohanna, Abdulkhalig Sallam

Saudi Medical Journal

Idiopathic hemihypertrophy is a congenital overgrowth disorder associated with an augmented risk for embryonal tumors. We present 4 cases of hemihypertrophy in Yemeni children living in Sana’a city. They presented to the outpatient clinics in a private hospital in Sana’a city, Yemen, over a period of 3 years from January 2009 to December 2011. The first 2 cases had no complaints apart from asymmetrical size of one side of their bodies (left side hemihypertrophy). The third case presented with left side hemihypertrophy and an abdominal mass, which upon referral to a cancer center was confirmed to be Wilms’ tumor. The …


Timing Of Dental Development In Saudi Cleft Lip And Palate Patients, Naif A. Bindayel, Maan A. Alsultan, Samar O. Elhayek Mar 2014

Timing Of Dental Development In Saudi Cleft Lip And Palate Patients, Naif A. Bindayel, Maan A. Alsultan, Samar O. Elhayek

Saudi Medical Journal

OBJECTIVE: To assess the timing of dental development in Saudi patients affected with non-syndromic cleft lip and palate (CLP), and further investigate patients9 demographics. METHODS: The panoramic radiographs of 51 Saudi subjects (5-14 years) with CLP were assessed cross-sectionally in January 2012. The data were collected at King Abdulaziz Medical City, Riyadh, Saudi Arabia, and the study was completed in February 2013. Demirjian9s method was used to evaluate the crown and root developmental stages of mandibular permanent teeth to quantify the dental age. Patients9 medical records were used to specify the chronological age, and utilized to divide all participating subjects …


Surgical Education On Youtube, Talal A. Al-Khatib Mar 2014

Surgical Education On Youtube, Talal A. Al-Khatib

Saudi Medical Journal

No abstract provided.


Comparison Of Stroke Volume Variation With Pulse Pressure Variation As A Diagnostic Indicator Of Fluid Responsiveness In Mechanically Ventilated Critically Ill Patients, Jin-Quan Hong, He-Fan He, Zhi-Yuan Chen, Zhen-Shuang Du, Wei-Feng Liu, Pei-Qing Weng, Hao-Bo Huang Mar 2014

Comparison Of Stroke Volume Variation With Pulse Pressure Variation As A Diagnostic Indicator Of Fluid Responsiveness In Mechanically Ventilated Critically Ill Patients, Jin-Quan Hong, He-Fan He, Zhi-Yuan Chen, Zhen-Shuang Du, Wei-Feng Liu, Pei-Qing Weng, Hao-Bo Huang

Saudi Medical Journal

OBJECTIVE: To compare the diagnostic accuracy of stroke volume variation (SVV) and pulse pressure variation (PPV) in studies that examined both parameters in the same patient population. METHODS: Literature search was conducted in PubMed, EMBASE, CINAHL, and Google Scholar. Receiver operator characteristic (ROC) curves were examined, and summary ROC curves were plotted. RESULTS: The study was conducted from January to July 2013 in The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China. The meta-analysis of 19 studies published during the years 2005 and 2013 revealed a high degree of diagnostic accuracy of both SVV and PPV in predicting …


Priorities For Primary Health Care Research In Qassim, Central Saudi Arabia, Saulat Jahan, Abdullah M. Al-Saigul, Suad E. Nimir, Amani S. Mustafa Mar 2014

Priorities For Primary Health Care Research In Qassim, Central Saudi Arabia, Saulat Jahan, Abdullah M. Al-Saigul, Suad E. Nimir, Amani S. Mustafa

Saudi Medical Journal

OBJECTIVE: To determine the major research priorities in the field of Primary Health Care (PHC) in Qassim, Saudi Arabia. METHODS: The study was a cross-sectional survey including academicians, researchers, and PHC program managers in Qassim. A self-administered questionnaire was used as the survey instrument. A scale of 1-5 was given for prioritizing the health issues (5=highest priority; 1=lowest priority). A list of PHC research topics including prevalent health issues addressed by PHC programs was provided to the respondents. Responses were collected from April 2012 to June 2012, and the data was analyzed. RESULTS: A total of 101 eligible participants were …


Bone Loss In Osteoporosis And Arthritis. Pathogenesis And Therapeutic Strategies, Mohammed M. Albogami, Ali S. Jawad, Rizgar A. Mageed Mar 2014

Bone Loss In Osteoporosis And Arthritis. Pathogenesis And Therapeutic Strategies, Mohammed M. Albogami, Ali S. Jawad, Rizgar A. Mageed

Saudi Medical Journal

Bone makes up a framework that provides protection for internal body organs. The homeostasis of bone is maintained by balanced old bone resorption and new bone formation. However, this balance can be altered such as in postmenopausal women, patients with some cancers, and patients with chronic inflammatory conditions such as rheumatoid arthritis. In recent years, the management of chronic inflammatory conditions was revolutionized by the use of biologic therapies that target key pro-inflammatory proteins and/or pathways. However, whilst the anti-inflammatory effect of these biologic agents is well-established, their effect on bone loss is just emerging. The use of these agents …


The Role Of Rapid Testing And Clinical Decision In The Diagnosis Of Human Influenza A H1n1 Infection, Abdulaziz A. Binsaeed, Amna R. Siddiqui, Ahmed M. Mandil, Armen A. Torchyan, Salwa A. Tayel, Shaffi A. Shaikh, Hanan A. Habib, Abdulaziz S. Al-Khattaf Mar 2014

The Role Of Rapid Testing And Clinical Decision In The Diagnosis Of Human Influenza A H1n1 Infection, Abdulaziz A. Binsaeed, Amna R. Siddiqui, Ahmed M. Mandil, Armen A. Torchyan, Salwa A. Tayel, Shaffi A. Shaikh, Hanan A. Habib, Abdulaziz S. Al-Khattaf

Saudi Medical Journal

OBJECTIVE: To evaluate the role of the rapid influenza diagnostic test (RIDT) and clinical decision in the diagnosis of H1N1. METHODS: In November 2009, 290 suspected influenza patients were examined for H1N1 during an outbreak in Riyadh, Saudi Arabia. Nasopharyngeal swabs were analyzed using Directigen EZ Flu A+B kit. Monoclonal anti-human influenza A/B and reverse transcription- polymerase chain reaction (RT-PCR) were used. Positive and negative controls were used in each run of specimens. Validity indices were calculated for RIDT and clinical diagnostic criteria. RESULTS: The sensitivity and specificity of RIDT were 40.5% (95% confidence interval [CI]: 33.0-48.5), and 94.5% (95% …


Hiv-Tat Mediated Protein Transduction Of Heme Oxygenase-1 Protects Hacat Cells From Ionizing Radiation, Pengfei Liu, Jiao Xue, Qing Gu, Jinyong Wu, Han Cao, Wei Zhu, Jundong Zhou, Jianping Cao, Shuyu Zhang Mar 2014

Hiv-Tat Mediated Protein Transduction Of Heme Oxygenase-1 Protects Hacat Cells From Ionizing Radiation, Pengfei Liu, Jiao Xue, Qing Gu, Jinyong Wu, Han Cao, Wei Zhu, Jundong Zhou, Jianping Cao, Shuyu Zhang

Saudi Medical Journal

OBJECTIVE: To elucidate the effects of human keratinocyte-derived HaCaT cells (HIV-TAT) protein transduction domains (PTD) coupled heme oxygenase-1 (HO-1) fusion protein (TAT-HO-1) on radiation-induced human keratinocyte-derived HaCaT cells. METHODS: This study was conducted between May 2010 and February 2013 in the School of Radiation Medicine and Protection, Soochow University, Suzhou, China. This experimental study was designed to explore the protective role of TAT-HO-1 in skin cells. The human HO-1 gene was fused with a gene fragment encoding TAT PTD to produce in-frame TAT-HO-1. The distribution of TAT-HO-1 was measured by immunostaining and Western blot. The radioprotection for TAT-HO-1 was determined …


Estrogen Deficiency Reduces The Expression Of Estrogen Receptor-Beta In Wistar Rats’ Periodontal Tissues, Mossad M. Al-Sherbini, Mohammad S. Al-Zahrani, Zienab A. Alrefaie, Hanan A. Amin, Khalid H. Zawawi Mar 2014

Estrogen Deficiency Reduces The Expression Of Estrogen Receptor-Beta In Wistar Rats’ Periodontal Tissues, Mossad M. Al-Sherbini, Mohammad S. Al-Zahrani, Zienab A. Alrefaie, Hanan A. Amin, Khalid H. Zawawi

Saudi Medical Journal

OBJECTIVE: To assess the effect of ovariectomy on the expression of estrogen receptor-beta (ER-beta) in periodontal ligament and alveolar bone. METHODS: This animal study was conducted at King Fahad Research Center, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia from March to October 2012. Thirty 12-week-old female Wistar rats were divided into 2 groups (15 each): ovariectomized (OVX) and sham-operated. Levels of estrogen and progesterone in the sera were measured using the enzyme linked immunosorbent assay (ELISA). To detect the expression of ER-beta, immunostaining was performed on the tibia, alveolar bone, and periodontal ligament specimens followed by quantitative histomorphometric analysis. …


The Role Of Genetic Polymorphisms In Endothelial Nitric Oxide Synthase And Beta2-Adrenergic Receptors With Risk Of Hypertension In A Sample Of Lebanese People, Nadia Y. Soudani, Rajaa M. Fakhoury, Samira S. Kaissi, Nathalie K. Zgheib Mar 2014

The Role Of Genetic Polymorphisms In Endothelial Nitric Oxide Synthase And Beta2-Adrenergic Receptors With Risk Of Hypertension In A Sample Of Lebanese People, Nadia Y. Soudani, Rajaa M. Fakhoury, Samira S. Kaissi, Nathalie K. Zgheib

Saudi Medical Journal

OBJECTIVE: To determine the allelic frequencies of endothelial nitric oxide synthase (eNOS) and beta2-adrenergic receptor (ADRB2) genetic polymorphisms in a sample of Lebanese participants, and to test their association with an increase in the risk of hypertension. METHODS: Endothelial nitric oxide synthase and ADRB2 genetic polymorphisms were studied in a case-control study that involved a sample of Lebanese participants (58.8% hypertensive and 41.2% controls), recruited at the American University of Beirut Medical Center, Beirut, Lebanon between March 2008 and August 2009. RESULTS: The results did not show any significant difference in the minor allele frequencies of aspartic acid (Asp) allele …


Prevention Of Ventilator-Associated Pneumonia. A Knowledge Survey Among Intensive Care Nurses In Yemen, Khaled M. Al-Sayaghi Mar 2014

Prevention Of Ventilator-Associated Pneumonia. A Knowledge Survey Among Intensive Care Nurses In Yemen, Khaled M. Al-Sayaghi

Saudi Medical Journal

OBJECTIVE: To evaluate knowledge of nurses working in Yemen intensive care units (ICUs) on evidence-based strategies for preventing ventilator-associated pneumonia (VAP), and to determine if there is any association between certain nurses’ as well as workplaces’ characteristics and the knowledge scores of nurses. METHODS: A descriptive cross-sectional survey was carried out in 37 ICUs of 23 hospitals in Sana’a city, Yemen. A self-administered multiple-choice questionnaire listing 15 evidence-based preventive strategies was distributed to all nurses and collected between December 2012 and February 2013. The results were analyzed and tabulated using the Statistical Package for Social Sciences Version 17. RESULTS: Three …


Catamenial Pneumothorax. Is It Time To Approach Differently?, Yasser Aljehani Feb 2014

Catamenial Pneumothorax. Is It Time To Approach Differently?, Yasser Aljehani

Saudi Medical Journal

Catamenial pneumothorax CP was considered a rare clinical entity that has gained tremendous interest recently. It is commonly overlooked, misdiagnosed, or under diagnosed. It is part of the thoracic endometriosis syndrome, which includes catamenial hemothorax, catamenial hemoptysis, and pulmonary endometriosis. These represent the spectrum of ectopic pelvic endometriosis. The presentation is variable leading to difficulty in developing a standardized approach to diagnosis and management. This review discusses the pathogenesis of these entities and the novel methods of investigation, management, and clinical protocols.


Chloral Hydrate Versus Midazolam As Sedative Agents For Diagnostic Procedures In Children, Omar M. Hijazi, Anwar E. Ahmed, Jaber A. Anazi, Hashim E. Al-Hashemi, Majed I. Al-Jeraisy Feb 2014

Chloral Hydrate Versus Midazolam As Sedative Agents For Diagnostic Procedures In Children, Omar M. Hijazi, Anwar E. Ahmed, Jaber A. Anazi, Hashim E. Al-Hashemi, Majed I. Al-Jeraisy

Saudi Medical Journal

OBJECTIVE: To compare sedation outcomes for chloral hydrate (CH) and midazolam (MD) as sedative agents for diagnostic procedures in children. METHODS: A prospective, randomized, double-blinded study conducted between July 2005 and October 2006, at the Pediatric Day Care Unit (DCU), King Abdulaziz Medical City, Riyadh, Saudi Arabia. After meeting the inclusion criteria and getting informed consent, patients were randomized, given the study drug, and monitored for sedation outcomes. RESULTS: Two hundred and seventy-five patients who had 292 sedation sessions for diagnostic procedures were included in the study. Due to missing data, 286 sedations were included in the final analysis; 144 …


Augmentation Index Is A Better Marker For Cardiovascular Risk In Young Malaysian Males. A Comparison Of Involvement Of Pulse Wave Velocity, Augmentation Index, And C-Reactive Protein, Amilia Aminuddin, Kalaivani Chellappan, Oteh Maskon, Zaiton Zakaria, Aminuddin A. Karim, Wan Z. Ngah, Noranita M. Nordin Feb 2014

Augmentation Index Is A Better Marker For Cardiovascular Risk In Young Malaysian Males. A Comparison Of Involvement Of Pulse Wave Velocity, Augmentation Index, And C-Reactive Protein, Amilia Aminuddin, Kalaivani Chellappan, Oteh Maskon, Zaiton Zakaria, Aminuddin A. Karim, Wan Z. Ngah, Noranita M. Nordin

Saudi Medical Journal

OBJECTIVE: To determine the association between carotid femoral pulse wave velocity (PWVCF) and augmentation index (AI) with future cardiovascular disease (CVD) risk, and to assess whether high sensitivity C-reactive protein (hs-CRP) is an important mediator towards these vascular changes, among young men. METHODS: This cross-sectional study was conducted at Universiti Kebangsaan Malaysia Medical Center, Kuala Lumpur, Malaysia from July 2011 to December 2012. Two hundred and eleven young men were recruited. The PWVCF and AI were measured using Vicorder. High sensitivity C-reactive protein was measured by using immunological methods. The future CVD risk was assessed by Framingham risk score (FRS) …


Determinants Of Hand Hygiene Non-Compliance In A Cardiac Center In Saudi Arabia, Daifallah J. Alnakhli, Kamran Baig, Aipeng Goh, Hassan Sandokji, Shaikh S. Din Feb 2014

Determinants Of Hand Hygiene Non-Compliance In A Cardiac Center In Saudi Arabia, Daifallah J. Alnakhli, Kamran Baig, Aipeng Goh, Hassan Sandokji, Shaikh S. Din

Saudi Medical Journal

OBJECTIVE: To evaluate the baseline hand hygiene non-compliance rate, and identify the factors associated with non-compliance in a cardiac center in Saudi Arabia. METHODS: This observational study was conducted in Prince Sultan Cardiac Center, Riyadh, Saudi Arabia, a 176 beds specialized cardiac center. In total, 6,022 observations were recorded by using the Infection Control Link Nurse program from all the high and non-high risk areas from October to December 2012. The data was collected from different healthcare workers (HCW) for World Health Organization 5 indications of hand hygiene. Non-compliance rate was calculated, and univariate and multivariate analysis was performed using …


Antibiotics Exposure, Risk Factors, And Outcomes With Candida Albicans And Non-Candida Albicans Candidemia. Results From A Multi-Center Study, Hao Wang, Da-Wei Wu, Hui Han, Jin-Feng Yue, Fan Zhang, Ti-Chao Shan, Hai-Peng Guo, Mei Yin Feb 2014

Antibiotics Exposure, Risk Factors, And Outcomes With Candida Albicans And Non-Candida Albicans Candidemia. Results From A Multi-Center Study, Hao Wang, Da-Wei Wu, Hui Han, Jin-Feng Yue, Fan Zhang, Ti-Chao Shan, Hai-Peng Guo, Mei Yin

Saudi Medical Journal

OBJECTIVE: To define the differences in antibiotics exposure, risk factors, and outcome in hospitalized patients with Candida albicans (C. albicans) and non-C. albicans candidemia. METHODS: This is a multi-center retrospective study of 132 patients with candidemia from 5 tertiary-care educational hospitals in Shandong, China conducted between January 2009 and June 2010. Fifty-six of 132 (42.4%) patients had candidemia due to C. albicans and 76/132 (57.6%) had non-C. albanians candidemia. RESULTS: Patients with non-C. albicans candidemia received anti-anaerobic agents more often (23.7% versus 8.9%; p=0.027) and beta-lactam/beta-lactamase inhibitors less often (34.2% versus 51.8%; p=0.043) than those with C. albicans candidemia. Independent …


Potential Risk Factors For Patient Mortality During Admission To The Intensive Care Units, Sevim Celik, Derya Sahin, Cigdem Korkmaz, Berna Kuzulu, Serap Cabar, Fatih Bahadir, Yildiz Yildiz Feb 2014

Potential Risk Factors For Patient Mortality During Admission To The Intensive Care Units, Sevim Celik, Derya Sahin, Cigdem Korkmaz, Berna Kuzulu, Serap Cabar, Fatih Bahadir, Yildiz Yildiz

Saudi Medical Journal

OBJECTIVE: To determine the prognostic importance of admission time, admission day, admission source, and route of admission, attached devices before admission, diagnosis of patients, and total Simplified Acute Physiology Score (SAPS) II score during admission on intensive care unit mortality rates. METHODS: This retrospective study was carried out with 545 patients admitted to adult intensive care units between January 2006 and January 2011 at Zonguldak, Turkey. Computerised database and patient records were used for data collection. Data from the patient records was collected by a constructed survey form and SAPS II scale. The data was evaluated by numeric values and …


Administered Antipsychotic Pro Re Nata Medications In Psychiatric Inpatients. Pre- And Post-Accreditation Comparison, Mohammed A. Al-Sughayir Feb 2014

Administered Antipsychotic Pro Re Nata Medications In Psychiatric Inpatients. Pre- And Post-Accreditation Comparison, Mohammed A. Al-Sughayir

Saudi Medical Journal

OBJECTIVE: To investigate whether the mental health accreditation program drives improvements in the clinical practice of giving pro re nata (PRN) antipsychotic medications for psychiatric inpatients. METHODS: This study was conducted in October 2012, a record-based pre-post assessment design in psychiatric inpatient wards at King Khalid University Hospital, Riyadh, Saudi Arabia. Data collected from a 12-month pre-accreditation period (July 2009 to June 2010) was compared with those from a 12-month post-accreditation period (July 2011 to June 2012). The collected data identified demographics, diagnosis, number of PRN antipsychotic medications administered per patient, and indications for use. RESULTS: There were 177 patients …


Prevalence Of Vitamin D Deficiency In Saudi Newborns At A Tertiary Care Center, Khalid M. Alfaleh, Abdulaziz M. Al-Manie, Hashem F. Al-Mahmoud, Hussam M. Al-Razqan, Ahmed B. Al-Mutlaq, Saud A. Al-Rumaih, Rana M. Hasanato, Hazem M. Al-Mandeel Feb 2014

Prevalence Of Vitamin D Deficiency In Saudi Newborns At A Tertiary Care Center, Khalid M. Alfaleh, Abdulaziz M. Al-Manie, Hashem F. Al-Mahmoud, Hussam M. Al-Razqan, Ahmed B. Al-Mutlaq, Saud A. Al-Rumaih, Rana M. Hasanato, Hazem M. Al-Mandeel

Saudi Medical Journal

OBJECTIVE: To evaluate vitamin D levels in Saudi newborns utilizing umbilical cord samples, and to benchmark the results with international figures. METHODS: This cross-sectional study was carried out at King Khalid University Hospital, Riyadh, Saudi Arabia between November 2013 and March 2013. Vitamin D levels were assessed in the umbilical cord of healthy term neonates born above 2.5 kg from healthy pregnant mothers. Gestational age (GA), birth weight, gender, levels of sun exposure, and consumption of vitamin D rich food data were collected. Our primary outcome was the percentage of newborns with vitamin D deficiency (vitamin D level below 25 …


Perceptions Of Saudi Medical Students On The Qualities Of Effective Teachers. A Cross Sectional Study, Abdulrahman A. Al-Mohaimeed, Nauman Z. Khan Feb 2014

Perceptions Of Saudi Medical Students On The Qualities Of Effective Teachers. A Cross Sectional Study, Abdulrahman A. Al-Mohaimeed, Nauman Z. Khan

Saudi Medical Journal

OBJECTIVE: To identify the attributes of an effective medical teacher that students value the most. METHODS: A quantitative survey was performed in the College of Medicine, Qassim University, Buraidah, Kingdom of Saudi Arabia, between April and May 2012, using a pretested self-administered questionnaire distributed to all students. It captured their opinions on the qualities and attributes of good teachers. Each item was measured on a 5-point Likert scale. Data were entered and analyzed using the Statistical Package for Social Sciences Version 17. RESULTS: Three hundred and fifty-six students from all years responded. The most important attributes from the students9 perspectives …


An Unusual Case Of Bezoar From Sudan, Nada H. Abdel-Rahman, Awad M. Ahmed Feb 2014

An Unusual Case Of Bezoar From Sudan, Nada H. Abdel-Rahman, Awad M. Ahmed

Saudi Medical Journal

Pica is an abnormal eating behavior in which patients persistently eat non-food materials, which can lead to health consequences. A man presented complaining of several months of back pain and constipation without vomiting, abdominal pain, or distension. He experienced increasing social isolation and emotional lability over 5 years. Radiological findings confirmed the diagnosis, noting multiple radiopaque foreign bodies. Several types of pica are described based on the substance consumed. Bezoars may develop in the gastrointestinal tract as a result of these ingestions. Lithobezoars are rare types of bezoars, more common in males and psychiatric patients. An important clue to the …


Pycnogenol Supplementation And Its Beneficial Effects In Healthy Rats, Pelin Aribal-Ayral, Guzin Ozelci-Kavas, Atilla H. Elhan Feb 2014

Pycnogenol Supplementation And Its Beneficial Effects In Healthy Rats, Pelin Aribal-Ayral, Guzin Ozelci-Kavas, Atilla H. Elhan

Saudi Medical Journal

No abstract provided.


Spectrum And Antimicrobial Resistance Of Uropathogens From Patients With Urinary Tract Infection In Urology And Non-Urology Departments, Qingmei Wang, Xiaobing Zhang, Peiyuan Xia, Yongchuan Chen, Qian Wang, Wei Feng, Fengjun Sun Feb 2014

Spectrum And Antimicrobial Resistance Of Uropathogens From Patients With Urinary Tract Infection In Urology And Non-Urology Departments, Qingmei Wang, Xiaobing Zhang, Peiyuan Xia, Yongchuan Chen, Qian Wang, Wei Feng, Fengjun Sun

Saudi Medical Journal

No abstract provided.


Effectiveness And Complication Rates Of Tension-Free Vaginal Tape, Transobturator Tape, And Tension-Free Vaginal Tape-Obturator In The Treatment Of Female Stress Urinary Incontinence In A Medium- To Long-Term Follow Up. Meta-Analysis Of Randomized Controlled Trials, Pan-Feng Tan, Lu-Lu Yang, Ru-Biao Ou, Ping Tang, Wen-Jun Yang, Jie-Bin Huang, Wei Wei, Xing-Hua Wei, Bin Wang, Ke-Ji Xie Jan 2014

Effectiveness And Complication Rates Of Tension-Free Vaginal Tape, Transobturator Tape, And Tension-Free Vaginal Tape-Obturator In The Treatment Of Female Stress Urinary Incontinence In A Medium- To Long-Term Follow Up. Meta-Analysis Of Randomized Controlled Trials, Pan-Feng Tan, Lu-Lu Yang, Ru-Biao Ou, Ping Tang, Wen-Jun Yang, Jie-Bin Huang, Wei Wei, Xing-Hua Wei, Bin Wang, Ke-Ji Xie

Saudi Medical Journal

OBJECTIVE: To evaluate the effectiveness and complications of tension-free vaginal tape (TVT), transobturator tape (TOT), and tension-free vaginal tape-obturator (TVT-O) in a medium- to long-term follow up. METHODS: We searched PubMed, EMBASE, Cochrane database, ClinicalTrials.gov, Google Scholar, and the International Continence Society (ICS) website from August to December 2012 in Guangzhou First People9s Hospital, Guangzhou, China. Randomized controlled trials (RCTs) comparing the effectiveness and complications of TVT, TOT, and TVT-O were selected. RESULTS: Forty RCTs were included. The TVT and TOT had similar subjective (risk ratio [RR]: 0.99; 95% confidence interval [CI]: 0.93-1.04), and objective cure rates (RR: 0.96; 95% …