Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Articles 2011 - 2040 of 5073

Full-Text Articles in Entire DC Network

Health Care Services Provided To Type 1 And Type 2 Diabetic Patients In Saudi Arabia, Khalid A. Al-Rubeaan, Hamad A. Al-Manaa, Tawfik A. Khoja, Ahmad H. Al-Sharqawi, Khaled H. Aburisheh, Amira M. Youssef, Metib S. Alotaibi, Ali A. Al-Gamdi Oct 2015

Health Care Services Provided To Type 1 And Type 2 Diabetic Patients In Saudi Arabia, Khalid A. Al-Rubeaan, Hamad A. Al-Manaa, Tawfik A. Khoja, Ahmad H. Al-Sharqawi, Khaled H. Aburisheh, Amira M. Youssef, Metib S. Alotaibi, Ali A. Al-Gamdi

Saudi Medical Journal

Objectives: To assess health care services provided to type 1 and type 2 diabetic patients and diabetes health care expenditure in the Kingdom of Saudi Arabia (KSA). Methods: This study was part of a nationwide, household, population based cross-sectional survey conducted at the University Diabetes Center, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia between January 2007 and December 2009 covering 13 administrative regions of the Kingdom. Using patients’ interview questionnaires, health care services data were collected by trained staff. Results: A total of 5,983 diabetic patients were chosen to assess health care services and expenditure. Approximately …


Systematic Reviews: Minimizing Search Bias, Fikri M. Abu-Zidan Oct 2015

Systematic Reviews: Minimizing Search Bias, Fikri M. Abu-Zidan

Saudi Medical Journal

No abstract provided.


Can Mean Platelet Volume And Mean Platelet Volume/Platelet Count Ratio Be Used As A Diagnostic Marker For Sepsis And Systemic Inflammatory Response Syndrome?, Selma Ates, Hafıze Oksuz, Bırsen Dogu, Fulsen Bozkus, Hasan Ucmak, Fadime Yanıt Oct 2015

Can Mean Platelet Volume And Mean Platelet Volume/Platelet Count Ratio Be Used As A Diagnostic Marker For Sepsis And Systemic Inflammatory Response Syndrome?, Selma Ates, Hafıze Oksuz, Bırsen Dogu, Fulsen Bozkus, Hasan Ucmak, Fadime Yanıt

Saudi Medical Journal

Objectives: To determine whether the mean platelet volume (MPV) and MPV/platelet (PLT) values can be used in the study of sepsis and systemic inflammatory response syndrome (SIRS). Methods: In this retrospective case-controlled study, 69 sepsis, 69 SIRS patients, and 72 control group who were treated in the years 2012-2013 were reviewed, and both the MPV and MPV/PLT rates were evaluated in all groups at Kahramanmaras Sutcu Imam University Intensive Care Unit, Kahramanmaras, Turkey. Results: Statistically significant difference was found between sepsis, SIRS, and control groups when comparing the MPV and MPV/PLT ratio ( p <0.05), and no significant difference was found between sepsis and SIRS groups in terms of MPV and MPV/PLT ratio ( p >0.05). Mean platelet volume values for …


A Cross-Sectional Study Of Anxiety And Marital Quality Among Women With Breast Cancer At A University Clinic In Western Saudi Arabia, Faten N. Al-Zaben, Mohammad G. Sehlo, Harold G. Koenig Oct 2015

A Cross-Sectional Study Of Anxiety And Marital Quality Among Women With Breast Cancer At A University Clinic In Western Saudi Arabia, Faten N. Al-Zaben, Mohammad G. Sehlo, Harold G. Koenig

Saudi Medical Journal

Objectives: To examine relationship between the quality of marital relationship and anxiety among women with breast cancer (BC) in the Kingdom of Saudi Arabia (KSA). Methods: This cross-sectional study recruited a consecutive series of 49 married women with BC seen in the Al-Amoudi Breast Cancer Center of Excellence at King Abdulaziz University, Jeddah, KSA in early 2013. Participants completed the Hospital Anxiety and Depression Scale, Spouse Perception Scale, and Quality of Marriage Index forms, and answered questions on demographic and cancer characteristics. Results: Anxiety symptoms indicating “possible” anxiety disorder were present in 10.4% and “probable” anxiety disorder in 14.6% (25% …


The Role Of Renin-Angiotensin Aldosterone System Related Micro-Ribonucleic Acids In Hypertension, Hui-Bo Wang, Jun Yang Oct 2015

The Role Of Renin-Angiotensin Aldosterone System Related Micro-Ribonucleic Acids In Hypertension, Hui-Bo Wang, Jun Yang

Saudi Medical Journal

Micro-ribonucleic acids (miRNAs) are small (21-25 nucleotide) single-stranded, evolutionarily conserved non-protein-coding RNAs, which control diverse cellular functions by interacting with the 3’ untranslated region of specific target messenger RNAs at the post-transcriptional level. Research shows that an aberrant expression profile of miRNAs has been linked to a series of diseases, including hypertension. In the past few decades, it has been demonstrated that excessive activation of the renin-angiotensin aldosterone system (RAAS) involves in the pathogenesis of hypertension. This article reviews the latest insights in the identification of RAAS-correlative miRNAs and the potential mechanisms for their roles in hypertension.


In This Issuereview Articleoriginal Articles Oct 2015

In This Issuereview Articleoriginal Articles

Saudi Medical Journal

No abstract provided.


Osteoporosis In Saudi Arabia: Are We Doing Enough?, Basmah K. Alwahhabi Oct 2015

Osteoporosis In Saudi Arabia: Are We Doing Enough?, Basmah K. Alwahhabi

Saudi Medical Journal

No abstract provided.


Recent Incidence And Descriptive Epidemiological Survey Of Breast Cancer In Saudi Arabia, Shalini Saggu, Hasibur Rehman, Zahid K. Abbas, Abid A. Ansari Oct 2015

Recent Incidence And Descriptive Epidemiological Survey Of Breast Cancer In Saudi Arabia, Shalini Saggu, Hasibur Rehman, Zahid K. Abbas, Abid A. Ansari

Saudi Medical Journal

Objectives: To review and analyze the pattern of breast cancer (BC) in the Kingdom of Saudi Arabia (KSA). Methods: A retrospective descriptive epidemiological review of BC of all diagnosed Saudi female cases from January 1990 to December 2014 was conducted at the Faculty of Sciences, Department of Biology, University of Tabuk, Tabuk, KSA. This report contains information obtained from the Saudi Cancer Registry and from King Faisal Specialist Hospital and Research Center. Results: The number of women with BC increased steadily from 1990-2010. On the basis of the number of cases, the percentage distribution of BC appears to be increasing. …


Comparison Of Solifenacin And Fesoterodine In Treatment Of Overactive Bladder, Önder Ercan, Bülent Köstü, Murat Bakacak, Yusuf Aytaç-Tohma, Bora Çoşkun, Fazıl Avcı, Erkan Efe Oct 2015

Comparison Of Solifenacin And Fesoterodine In Treatment Of Overactive Bladder, Önder Ercan, Bülent Köstü, Murat Bakacak, Yusuf Aytaç-Tohma, Bora Çoşkun, Fazıl Avcı, Erkan Efe

Saudi Medical Journal

Objectives: To compare the use of solifenacin and fesoterodine in treatment of overactive bladder (OAB). Methods: This prospective study was conducted on patients diagnosed with OAB who presenting to the Department of Obstetrics and Gynecology and Urology, School of Medicine, Kahramanmaraş Sütçü İmam University, Kahramanmaraş, Turkey between October 2013 and August 2014. Patients were randomized into 2 groups. Group 1 (n=60) received 5 mg solifenacin per day, while Group 2 (n=59) received 4 mg fesoterodine per day. All the patients’ OAB symptom scores (OABSS) in weeks 0, 4, and 12 were recorded. In addition, treatment costs and side effects of …


Indications For Eye Removal Surgeries: A 15-Year Experience At A Tertiary Military Hospital, Mehmet T. Koylu, Gokcen Gokce, Yusuf Uysal, Osman M. Ceylan, Dorukcan Akıncıoglu, Armagan Gunal Oct 2015

Indications For Eye Removal Surgeries: A 15-Year Experience At A Tertiary Military Hospital, Mehmet T. Koylu, Gokcen Gokce, Yusuf Uysal, Osman M. Ceylan, Dorukcan Akıncıoglu, Armagan Gunal

Saudi Medical Journal

Objectives: To analyze the indications and types of eye removals at a military tertiary care hospital in Turkey. Methods: The medical records (age, gender, affected eye, type of surgical procedure, indications of surgery) of 123 patients who underwent evisceration and enucleation in the course of a 15-year period (January 2000 to December 2014) at Gulhane Military Medical Academy, Ankara, Turkey were reviewed retrospectively. Results: The mean age was 35.61±18.52 (range 3-80 years). The number of male in the patient group was 92 (74.8%) and female was 31 (25.2%). Patients who underwent evisceration were 95 (77.2%), whereas 28 (22.8%) of them …


The Association Between Diabetes And Depression, Essmat M. Gemeay, Salma A. Moawed, Essmat A. Mansour, Nagat E. Ebrahiem, Ihab M. Moussa, Wafaa O. Nadrah Oct 2015

The Association Between Diabetes And Depression, Essmat M. Gemeay, Salma A. Moawed, Essmat A. Mansour, Nagat E. Ebrahiem, Ihab M. Moussa, Wafaa O. Nadrah

Saudi Medical Journal

Objectives: To evaluate the frequency of depression among Saudi patients, and to correlate between the presence of depression and type of diabetes. Methods: The research approach was descriptive with a convenient subject of 100 male and female patients (27 subjects with Type 1 diabetes, 29 subjects with Type 2 diabetes, and 44 subjects with gestational diabetes) from March to June 2014 at Al-Solimania Primary Health Care Center, Al-Olaya, Riyadh, Kingdom of Saudi Arabia. Patients were interviewed individually using an interview questionnaire sheet formulated by researchers to assess lifestyle items, and Beck depression inventory was used to screen for depression. Results: …


Resident Physician’S Knowledge And Attitudes Toward Biostatistics And Research Methods Concepts, Sami H. Al-Zahrani Oct 2015

Resident Physician’S Knowledge And Attitudes Toward Biostatistics And Research Methods Concepts, Sami H. Al-Zahrani

Saudi Medical Journal

Objectives: To assess the knowledge and attitudes of resident physicians toward biostatistics and research methodology concepts. Methods: We conducted a cross-sectional study between November 2014 and October 2014 at King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia. A self-administered questionnaire was distributed to all participants. The response rate was 90%. Results: One hundred sixty-two resident completed the questionnaire. Most residents were well-informed in basic concepts, such as, “ P ” values, study power, and case control studies; more than half had confidence in interpreting the results of scientific papers. Conversely, more than 67% of the residents were not knowledgeable …


Ultrasound Imaging Accurately Identifies The Intercostobrachial Nerve, Ahmed K. Thallaj, Tariq A. Alzahrani, Salah N. El-Tallawy, Abdulaziz A. Alsaif, Mohannad Alnajjar Oct 2015

Ultrasound Imaging Accurately Identifies The Intercostobrachial Nerve, Ahmed K. Thallaj, Tariq A. Alzahrani, Salah N. El-Tallawy, Abdulaziz A. Alsaif, Mohannad Alnajjar

Saudi Medical Journal

Objectives: To test the hypothesis that identification and blockade of the intercostobrachial nerve (ICBN) can be achieved under ultrasound (US) guidance using a small volume of local anesthetic. Methods: Twenty-eight adult male volunteers were examined at King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia from November 2012 to September 2013. Intercostobrachial nerve blockade was performed using one ml of 2% lidocaine under US guidance. A sensory map of the blocked area was developed relative to the medial aspect of the humeral head. Results: The ICBN appears as a hyper-echoic structure. The nerve diameter was 2.3±0.28 mm, and the depth …


Fate Of Registered Clinical Trials Performed In Saudi Arabia, Abdulhakim B. Jamjoom, Ammer M. Jamjoom, Afnan M. Samman, Abdulhadi Y. Gahtani Oct 2015

Fate Of Registered Clinical Trials Performed In Saudi Arabia, Abdulhakim B. Jamjoom, Ammer M. Jamjoom, Afnan M. Samman, Abdulhadi Y. Gahtani

Saudi Medical Journal

No abstract provided.


Comparative Analysis Of Quantity And Quality Of Biomedical Publications In Gulf Cooperation Council Countries From 2011-2013, Reema B. Abu-Dawas, Muaz A. Mallick, Reem E. Hamadah, Razan H. Kharraz, Ranim A. Chamseddin, Tehreem A. Khan, Abdulhadi A. Alamodi, Dileep K. Rohra Sep 2015

Comparative Analysis Of Quantity And Quality Of Biomedical Publications In Gulf Cooperation Council Countries From 2011-2013, Reema B. Abu-Dawas, Muaz A. Mallick, Reem E. Hamadah, Razan H. Kharraz, Ranim A. Chamseddin, Tehreem A. Khan, Abdulhadi A. Alamodi, Dileep K. Rohra

Saudi Medical Journal

Objectives: To compare the research productivity of different Gulf Cooperation Council (GCC) countries in the field of biomedical sciences from 2011-2013. Methods: This is a retrospective study conducted in the College of Medicine, Alfaisal University, Riyadh, Saudi Arabia. Data on the biomedical publications originating from GCC countries published between January 2011 to December 2013 was searched via MEDLINE using PubMed. The total number of publications emanating from each country was normalized with the country’s population. The mean impact factor (IF) of all the publications in a year was calculated for comparative analysis. Results: A total of 11,000 publications were retrieved …


Pemphigus And Pregnancy: Analysis And Summary Of Case Reports Over 49 Years, Lin Lin, Xin Zeng, Qianming Chen Sep 2015

Pemphigus And Pregnancy: Analysis And Summary Of Case Reports Over 49 Years, Lin Lin, Xin Zeng, Qianming Chen

Saudi Medical Journal

Pemphigus is a group of immune-mediated bullous disorders, which often cause fragile blisters and extensive lesions of the skin or mucous membranes, such as in the mouth. This disease could be life-threatening in some cases. During pregnancy, its condition will become more complicated due to the change in the mother’s hormone level and the effect of drug therapy on both the mother and her fetus. Thus, it will be more difficult to identify the clinical manifestations and to establish the treatment plan. In this article, we present a comprehensive review of pemphigus and pregnancy by analyzing 47 cases of pemphigus …


Evaluation Of The Relationship Between T663a Polymorphism In The Alpha-Epithelial Sodium Channel Gene And Essential Hypertension, Wenchao Yang, Zhenmin Zhu, Jin Wang, Wei Ye, Yong Ding Sep 2015

Evaluation Of The Relationship Between T663a Polymorphism In The Alpha-Epithelial Sodium Channel Gene And Essential Hypertension, Wenchao Yang, Zhenmin Zhu, Jin Wang, Wei Ye, Yong Ding

Saudi Medical Journal

Objectives: To evaluate the relationship between alpha epithelial sodium channel (alpha-ENaC) T663A polymorphism and the risk of essential hypertension. Methods: This meta-analysis was conducted between November 2014 and February 2015 in Shanghai Medical Instrumentation College, Shanghai, China. We collected all published available case-control data (N=12) identified through PubMed, Web of Science, Scopus, and Chinese National Knowledge Infrastructure (CNKI) up to December 2014. The pooled odds ratio (OR) with 95% confidence interval (CI) was calculated using the fixed- or random-effect model. Results: Although subgroup analysis showed that alpha-ENaC T663A polymorphism was associated with essential hypertension in North American individuals (OR=1.55, 95% …


L-Carnitine Reduces Acute Lung Injury In Experimental Biliary Obstruction, Ozgur Kaya, Yavuz S. Koca, Ibrahim Barut, Sirin Baspinar, Mehmet Z. Sabuncuoglu Sep 2015

L-Carnitine Reduces Acute Lung Injury In Experimental Biliary Obstruction, Ozgur Kaya, Yavuz S. Koca, Ibrahim Barut, Sirin Baspinar, Mehmet Z. Sabuncuoglu

Saudi Medical Journal

Objectives: To investigate the protective effects of L-carnitine (LC) on lungs in an experimental obstructive jaundice (OJ) model. Methods: This was conducted for 2 months between May 2011 and July 2011 at Suleyman Demirel University School of Medicine Experimental and Clinical Research Center, Isparta, Turkey. Thirty-eight Wistar-Albino rats with an average weight of 250-300 g were divided into 3 groups of control, OJ, and OJ + L-carnitine treatment (LCT). L-carnitine was injected intravenously into the tail vein at a dose of 50 mg/kg/day for 10 days to the LCT group. Animals were sacrificed 10 days later. Enzyme levels were measured …


Sentinel Lymph Node Biopsy In Breast Cancer, Abdulaziz A. Alsaif Sep 2015

Sentinel Lymph Node Biopsy In Breast Cancer, Abdulaziz A. Alsaif

Saudi Medical Journal

Objectives: To report our experience in sentinel lymph node biopsy (SLNB) in early breast cancer. Methods: This is a retrospective study conducted at King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia between January 2005 and December 2014. There were 120 patients who underwent SLNB with frozen section examination. Data collected included the characteristics of patients, index tumor, and sentinel node (SN), SLNB results, axillary recurrence rate and SLNB morbidity. Results: There were 120 patients who had 123 cancers. Sentinel node was identified in 117 patients having 120 tumors (97.6% success rate). No SN was found intraoperatively in 3 patients. …


High Prevalence Of Iron Deficiency Anemia In Infants Attending A Well-Baby Clinic In Northwestern Saudi Arabia, Sami A. Al-Rehali, Amani M. Mahros, Ali M. Al-Sisi, Khalid D. Al-Harbi, Ahmed M. Yousef Sep 2015

High Prevalence Of Iron Deficiency Anemia In Infants Attending A Well-Baby Clinic In Northwestern Saudi Arabia, Sami A. Al-Rehali, Amani M. Mahros, Ali M. Al-Sisi, Khalid D. Al-Harbi, Ahmed M. Yousef

Saudi Medical Journal

Objectives: To determine the prevalence of iron deficiency anemia (IDA) in infants aged 6-24 months attending the well-baby clinic in primary health care centers (PHCCs). Methods: This cross-sectional epidemiological study was conducted in the Northwestern region of Saudi Arabia from April 2013 to January 2014 in 5 randomly selected PHCCs. The sample size comprised 500 infants, with 100 infants screened from each PHC. Blood samples were obtained for estimation of hemoglobin and serum ferritin levels. Results: Out of 500 infants, 246 (49%) cases had IDA with a mean age of 15.4 ± 6.5 months, with 130 (53%) males, and 116 …


Birth Prevalence Of Non-Syndromic Orofacial Clefts In Saudi Arabia And The Effects Of Parental Consanguinity, Heba J. Sabbagh, Nicola P. Innes, Bahauddin I. Sallout, Najlaa M. Alamoudi, Mustafa A. Hamdan, Nasir Alhamlan, Amaal I. Al-Khozami, Fatma D. Abdulhameed, Jumana Y. Al-Aama, Peter A. Mossey Sep 2015

Birth Prevalence Of Non-Syndromic Orofacial Clefts In Saudi Arabia And The Effects Of Parental Consanguinity, Heba J. Sabbagh, Nicola P. Innes, Bahauddin I. Sallout, Najlaa M. Alamoudi, Mustafa A. Hamdan, Nasir Alhamlan, Amaal I. Al-Khozami, Fatma D. Abdulhameed, Jumana Y. Al-Aama, Peter A. Mossey

Saudi Medical Journal

Objectives: To describe the characteristics and prevalence of non-syndromic orofacial clefting (NSOFC) and assess the effects of parental consanguinity on NSOFC phenotypes in the 3 main cities of Saudi Arabia. Methods: All infants (114,035) born at 3 referral centers in Riyadh, and 6 hospitals in Jeddah and Madinah between January 2010 and December 2011 were screened. The NSOFC cases (n=133) were identified and data was collected through clinical examination and records, and information on consanguinity through parent interviews. The diagnosis was confirmed by reviewing medical records and contacting the infants’ pediatricians. Control infants (n=233) matched for gender and born in …


Risk Factors Of Nasal Carriage Of Staphylococcus Aureus And Methicillin-Resistant Staphylococcus Aureus Among Health Care Staff In A Teaching Hospital In Central Saudi Arabia, Ohoud S. Al-Humaidan, Talat A. El-Kersh, Raid A. Al-Akeel Sep 2015

Risk Factors Of Nasal Carriage Of Staphylococcus Aureus And Methicillin-Resistant Staphylococcus Aureus Among Health Care Staff In A Teaching Hospital In Central Saudi Arabia, Ohoud S. Al-Humaidan, Talat A. El-Kersh, Raid A. Al-Akeel

Saudi Medical Journal

Objectives: To investigate possible risk factors of Staphylococcus aureus (S. aureus) and methicillin-resistant S. aureus (MRSA) nasal carriage associated with various health troubles among healthcare workers (HCWs) at King Khalid University Hospital (KKUH). Method: This prospective study was conducted between May 2012 and January 2013 in KKUH, Riyadh, Saudi Arabia. A total of 200 nasal swabs were collected from HCWs. Identification was carried out based on morphology, Gram stain, catalase and coagulase test, Staphaurex PlusH test, chromogenic medium, oxacillin, and cefoxitin test using disc diffusion method. Characterization was carried out using disk diffusion method and E-test. Polymerase chain reaction was …


Evaluation Of Health Care Services Provided For Older Adults In Primary Health Care Centers And Its Internal Environment: A Step Towards Age-Friendly Health Centers, Adel A. Alhamdan, Sulaiman A. Alshammari, Maysoon M. Al-Amoud, Tariq A. Hameed, Saad M. Bindawas, Saada M. Al-Orf, Ashry G. Mohamed, Essam A. Al-Ghamdi, Philip C. Calder Sep 2015

Evaluation Of Health Care Services Provided For Older Adults In Primary Health Care Centers And Its Internal Environment: A Step Towards Age-Friendly Health Centers, Adel A. Alhamdan, Sulaiman A. Alshammari, Maysoon M. Al-Amoud, Tariq A. Hameed, Saad M. Bindawas, Saada M. Al-Orf, Ashry G. Mohamed, Essam A. Al-Ghamdi, Philip C. Calder

Saudi Medical Journal

Objectives: To evaluate the health care services provided for older adults by primary health care centers (PHCCs) in Riyadh, Kingdom of Saudi Arabia (KSA), and the ease of use of these centers by older adults. Methods: Between October 2013 and January 2014, we conducted a descriptive cross-sectional study of 15 randomly selected PHCCs in Riyadh City, KSA. The evaluation focused on basic indicators of clinical services offered and factors indicative of the ease of use of the centers by older adults. Evaluations were based upon the age-friendly PHCCs toolkit of the World Health Organization. Results: Coverage of basic health assessments …


A Qualitative Exploration Of The Major Challenges Facing Pharmacovigilance In Saudi Arabia, Hisham Aljadhey, Mansour A. Mahmoud, Thamir M. Alshammari, Mohammed Al-Dhaeefi, Hervé Le Louet, Susana Perez-Gutthann, Peter J. Pitts Sep 2015

A Qualitative Exploration Of The Major Challenges Facing Pharmacovigilance In Saudi Arabia, Hisham Aljadhey, Mansour A. Mahmoud, Thamir M. Alshammari, Mohammed Al-Dhaeefi, Hervé Le Louet, Susana Perez-Gutthann, Peter J. Pitts

Saudi Medical Journal

Objectives: To explore the challenges facing pharmacovigilance in Saudi Arabia and formulate recommendations to improve it from the perspective of healthcare professionals in Saudi Arabia. Methods: This was a qualitative study of 4 focus group discussions with pharmacists, physicians, and academicians held under the auspices of the King Saud University School of Pharmacy and the Center for Medicine in the Public Interest, Riyadh, Saudi Arabia. A total of 29 eligible healthcare professionals were invited to participate in the discussion. The predefined themes of the study were the current practice and major challenges facing pharmacovigilance in regulatory bodies, hospitals, the community, …


Identification Of 2 Novel Homozygous Mutations In The Methylmalonyl-Coa Mutase Gene In Saudi Patients, Sarar Mohamed, Muddathir H. Hamad, Khaled K. Abu-Amero Sep 2015

Identification Of 2 Novel Homozygous Mutations In The Methylmalonyl-Coa Mutase Gene In Saudi Patients, Sarar Mohamed, Muddathir H. Hamad, Khaled K. Abu-Amero

Saudi Medical Journal

The aim of this report is to analyze the clinical features, and mutations of the methylmalonyl CoA mutase (MUT) gene in 2 patients with methylmalonic aciduria (MMA) attending King Saud University Medical City, Riyadh, Saudi Arabia in January 2014. The infants aged 6 days (patient 1) and 3 months (patient 2) with sepsis-like picture, metabolic acidosis, and hyperammonemia were presented. Investigations revealed high propionylcarnitine (C3), elevated urinary methylmalonic acids, 3-hydroxypropionic acids and methylcitrate, consistent with MMA. Sanger-sequencing detected a homozygous novel mutation (c.329A>G; p.Y110C) in the MUT gene in patient 1 and a heterozygous in parents. This mutation is …


Obstetric Outcomes In Reduced And Non-Reduced Twin Pregnancies: A Single Hospital Experience, Ummkulthoum E. Alshelaly, Noor H. Al-Mousa, Wesam I. Kurdi Sep 2015

Obstetric Outcomes In Reduced And Non-Reduced Twin Pregnancies: A Single Hospital Experience, Ummkulthoum E. Alshelaly, Noor H. Al-Mousa, Wesam I. Kurdi

Saudi Medical Journal

Objectives: To compare pregnancy outcomes between high-order multiple pregnancies resulting from assisted reproductive technology (ART) reduced to twins and non-reduced pregnancies, and to evaluate indications for using ART. Methods: This is a descriptive retrospective review of women with high-order multiple pregnancies reduced to twin carried out at the Department of Obstetrics & Gynecology, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia between December 2010 and December 2013. The control group consisted of subjects with twin pregnancies who received their fertility treatment at the same hospital during the same period. Results: One hundred and twelve women were included in …


Diseases Pattern Among Patients Attending Holy Mosque (Haram) Medical Centers During Hajj 1434 (2013), Abdulrahman R. Bakhsh, Abdulfattah I. Sindy, Mostafa J. Baljoon, Khalid O. Dhafar, Zohair J. Gazzaz, Mukhtiar Baig, Basma A. Deiab Aug 2015

Diseases Pattern Among Patients Attending Holy Mosque (Haram) Medical Centers During Hajj 1434 (2013), Abdulrahman R. Bakhsh, Abdulfattah I. Sindy, Mostafa J. Baljoon, Khalid O. Dhafar, Zohair J. Gazzaz, Mukhtiar Baig, Basma A. Deiab

Saudi Medical Journal

Objective: To evaluate the diseases pattern among pilgrims attending the 2 Holy Mosque (Haram) Health Care Centers during the Hajj season 2013 (Hijra 1434). Methods: In this cross-sectional study, data was collected from 2 medical centers located in the Holy Mosque in Makkah city, Saudi Arabia, from the first of Dhul-Hijjah to sixteenth Dhul-Hijjah 1434. The present study was completed in 16 days (6th October to 21st October 2013). Results: Over 16 days, 1008 patients attended the medical centers during Hajj 1434, (2013), out of which 554 (55%) were males and 454 (45%) were females. Most of the patients were …


Radiographic Assessment Of Impacted Teeth And Associated Pathosis Prevalence: Pattern Of Occurrence At Different Ages In Saudi Male In Western Saudi Arabia, Sara M. El-Khateeb, Eman A. Arnout, Tamer Hifnawy Aug 2015

Radiographic Assessment Of Impacted Teeth And Associated Pathosis Prevalence: Pattern Of Occurrence At Different Ages In Saudi Male In Western Saudi Arabia, Sara M. El-Khateeb, Eman A. Arnout, Tamer Hifnawy

Saudi Medical Journal

Objectives: To assess the prevalence of both impaction and associated pathosis in a Saudi population in Al-Madinah, Saudi Arabia based on digital panoramic radiographs. Methods: This study was carried out from December 2013 to February 2015. Panoramic radiographs of 359 male patients attending the Oral Diagnosis Clinics, Faculty of Dentistry, Taibah University, Al-Madinah, Saudi Arabia were reviewed. All images were evaluated to determine the prevalence and pattern of impacted third molars and canines, and associated pathosis. Results: Among 359 panoramic radiographs examined, 124 patients had impacted teeth. The impacted mandibular third molars were the most prevalent impacted teeth, 77.6% had …


An Unusual Outcome Of A Giant Ventral Hernia, Muhammad Waheed, Mohammad Alsenani, Muhammad Al-Akeely, Hamad Al-Qahtani Aug 2015

An Unusual Outcome Of A Giant Ventral Hernia, Muhammad Waheed, Mohammad Alsenani, Muhammad Al-Akeely, Hamad Al-Qahtani

Saudi Medical Journal

Hernias are routine general surgical problems that may present in any age group, regardless of the patient’s socioeconomic status. We present a rare case of a complicated ventral hernia leading to short bowel. This is an unusual case and is very rarely reported in the literature. This current case report describes a 54-year-old gentleman who presented to the hospital with a giant strangulated ventral hernia causing massive bowel ischemia and resulting in a short bowel. The literature on large abdominal wall hernias leading to short bowel is reviewed, and a discussion on short bowel syndrome is also presented.


New Report Shows That 400 Million Do Not Have Access To Essential Health Services Aug 2015

New Report Shows That 400 Million Do Not Have Access To Essential Health Services

Saudi Medical Journal

No abstract provided.