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Articles 1981 - 2010 of 5073
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Who Checklist Targets Major Causes Of Maternal And Newborn Deaths In Health Facilities
Who Checklist Targets Major Causes Of Maternal And Newborn Deaths In Health Facilities
Saudi Medical Journal
No abstract provided.
Preoperative Duplex Ultrasound Parameters Predicting Male Fertility After Successful Varicocelectomy, Fahad M. Alshehri, Mahboob H. Akbar, Adel K. Altwairgi, Omar J. Althaqufi
Preoperative Duplex Ultrasound Parameters Predicting Male Fertility After Successful Varicocelectomy, Fahad M. Alshehri, Mahboob H. Akbar, Adel K. Altwairgi, Omar J. Althaqufi
Saudi Medical Journal
Objectives: To assess duplex ultrasound (DUS) parameters, and predicti the outcome of varicocele ligation in male infertility. Methods: This retrospective and follow up study was conducted at Dr. Sulaiman Al Habib Hospital, AlQassim, Saudi Arabia between January 2011 and December 2012. Eighty-two patients were selected, who presented with clinical/subclinical varicocele and male infertility. All these patients had DUS of the scrotum and underwent for low ligation varicocelectomy. These patients were followed for a period of 12-24 months after surgery for the occurrence of paternity. We reviewed pre-operative scrotal DUS of these 82 patients for the testicular size and volume, pampiniform …
Aligning The Saudimed Framework With The National Commission For Academic Accreditation And Assessment Domains, Ara S. Tekian
Aligning The Saudimed Framework With The National Commission For Academic Accreditation And Assessment Domains, Ara S. Tekian
Saudi Medical Journal
No abstract provided.
Treatment Of Ventilator-Associated Pneumonia And Ventilator-Associated Tracheobronchitis In The Intensive Care Unit: A National Survey Of Clinicians And Pharmacists In Saudi Arabia, Awad Al-Omari, Masood Mohammed, Waleed Alhazzani, Hasan M. Al-Dorzi, Mohammed S. Belal, Ali O. Albshabshe, Maha F. Al-Subaie, Yaseen M. Arabi
Treatment Of Ventilator-Associated Pneumonia And Ventilator-Associated Tracheobronchitis In The Intensive Care Unit: A National Survey Of Clinicians And Pharmacists In Saudi Arabia, Awad Al-Omari, Masood Mohammed, Waleed Alhazzani, Hasan M. Al-Dorzi, Mohammed S. Belal, Ali O. Albshabshe, Maha F. Al-Subaie, Yaseen M. Arabi
Saudi Medical Journal
Objectives: To assess current practices of different healthcare providers for treating extensively drug-resistant (XDR) Acinetobacter baumannii (AB) infections in tertiary-care centers in Saudi Arabia. Methods: This cross-sectional study was performed in tertiary-care centers of Saudi Arabia between March and June 2014. A questionnaire consisting of 3 parts (respondent characteristics; case scenarios on ventilator-associated pneumonia [VAP] and tracheobronchitis [VAT], and antibiotic choices in each scenario) was developed and sent electronically to participants in 34 centers across Saudi Arabia. Results: One-hundred and eighty-three respondents completed the survey. Most of the respondents (54.6%) preferred to use colistin-based combination therapy to treat VAP caused …
Spontaneous Achilles Tendon Rupture In Alkaptonuria, Omar A. Alajoulin, Mohammed S. Alsbou, Somayya O. Ja’Afreh, Heba M. Kalbouneh
Spontaneous Achilles Tendon Rupture In Alkaptonuria, Omar A. Alajoulin, Mohammed S. Alsbou, Somayya O. Ja’Afreh, Heba M. Kalbouneh
Saudi Medical Journal
Alkaptonuria (AKU) is a rare inborn metabolic disease characterized by accumulation of homogentisic acid (HGA). Excretion of HGA in urine causes darkening of urine and its deposition in connective tissues causes dark pigmentation (ochronosis), early degeneration of articular cartilage, weakening of the tendons, and subsequent rupture. In this case report, we present a rare case of a patient presented with unilateral spontaneous rupture of Achilles tendon due to AKU. The patient developed most of the orthopedic manifestations of the disease earlier than typical presentations. Alkaptonuria patients should avoid strenuous exercises and foot straining especially in patients developing early orthopedic manifestations.
Platelet Changes In Healthy Male Smokers: Scientific Views, Nik Kosai, Reynu Rajan, Srijit Das
Platelet Changes In Healthy Male Smokers: Scientific Views, Nik Kosai, Reynu Rajan, Srijit Das
Saudi Medical Journal
No abstract provided.
Effects Of 12-Month, 2000iu/Day Vitamin D Supplementation On Treatment Naïve And Vitamin D Deficient Saudi Type 2 Diabetic Patients, Abdulaziz M. Al-Othman, Nasser M. Al-Daghri, Shaun B. Sabico
Effects Of 12-Month, 2000iu/Day Vitamin D Supplementation On Treatment Naïve And Vitamin D Deficient Saudi Type 2 Diabetic Patients, Abdulaziz M. Al-Othman, Nasser M. Al-Daghri, Shaun B. Sabico
Saudi Medical Journal
Objectives: To determine whether 12-month, 2000IU/day vitamin D supplementation cardiometabolically improves treatment naïve type 2 diabetes mellitus (T2DM) Saudi patients with vitamin D deficiency. Methods: This 12-month interventional study was conducted at primary health centers in 5 different residential areas in Riyadh, Saudi Arabia between January 2013 and January 2014. Forty-five Saudi T2DM patients were enrolled. Baseline anthropometrics, glycemic, and lipid profiles were measured and repeated after 6 and 12 months. All subjects were provided with 2000IU vitamin D supplements for one year. Results: Vitamin D deficiency at baseline was 46.7%, 31.8% after 6 months, and 35.6% after 12 months, …
The Association Between The Cc Chemokine Ligand 5 -28c>G Gene Polymorphism And Tuberculosis Susceptibility, Hongfang Lu, Jingang Wang, Baoan Gao, Shixiong Chen, Guangming Xiang, Shaojuan Yang, Yuan Gong, Li Guan
The Association Between The Cc Chemokine Ligand 5 -28c>G Gene Polymorphism And Tuberculosis Susceptibility, Hongfang Lu, Jingang Wang, Baoan Gao, Shixiong Chen, Guangming Xiang, Shaojuan Yang, Yuan Gong, Li Guan
Saudi Medical Journal
Objectives: To assess the association between chemotactic chemokine (C-C motif) ligand 5 (CCL5) -28C>G polymorphism and tuberculosis (TB) risk. Methods: PubMed, Web of Science, and WanFang were searched up to April 2015 for eligible studies on CCL5 -28C>G polymorphism. Data was extracted, and pooled odd ratios (ORs) as well as 95% confidence intervals (95% CI) were calculated. Results: Eight case-control studies were extracted from 8 articles on the polymorphism involving 1852 TB cases and 2068 controls. The results of meta-analysis showed that significant reduced risks were found for the polymorphism with the risk of TB in Asians and …
Lack Of Association Between The Insulin Receptor Substrates-1 Gly972arg Polymorphism And Type-2 Diabetes Mellitus Among Saudis From Eastern Saudi Arabia, Hawra A. Alsalman, Yahia A. Kaabi
Lack Of Association Between The Insulin Receptor Substrates-1 Gly972arg Polymorphism And Type-2 Diabetes Mellitus Among Saudis From Eastern Saudi Arabia, Hawra A. Alsalman, Yahia A. Kaabi
Saudi Medical Journal
Objectives: To investigate the association between the insulin receptor substrate-1 ( IRS1 ) Gly972Arg polymorphism and type-2 diabetes mellitus (T2DM) among Saudis from Eastern Saudi Arabia. Methods: This study was conducted between May and December 2014 at King Fahad Hospital of the University, Al-Khobar, Kingdom of Saudi Arabia. In a case-control study design, a total of 143 subjects (age range: 35-73 years) comprising 74 healthy controls and 69 patients with T2DM were examined. Blood samples were collected from subjects and subjected to genomic DNA extraction and chemical analysis. The IRS1 Gly972Arg polymorphism was then genotyped using the standard polymerase chain …
Does Social Support Affect Development Of Cognitive Dysfunction In Individuals With Diabetes Mellitus?, Feride T. Yilmaz, Selma Sabancıogullari, Kadriye Aldemir, Azime K. Kumsar
Does Social Support Affect Development Of Cognitive Dysfunction In Individuals With Diabetes Mellitus?, Feride T. Yilmaz, Selma Sabancıogullari, Kadriye Aldemir, Azime K. Kumsar
Saudi Medical Journal
Objectives: To determine cognitive functions and perceived social support (SS) among individuals with diabetes mellitus (DM), and the effects of SS on the development of cognitive dysfunction (CD). Methods: This cross-sectional study was conducted in 121 patients with DM presenting at the Endocrinology Clinic of Cumhuriyet University Health Services Application and Research Hospital, Sivas, Turkey between April and June 2014. Data were collected utilizing the “Patient Assessment Form”, “Standardized Mini Mental State Examination (SMMSE)”, and “Multidimensional Scale of Perceived Social Support (MSPSS)”. Results: The mean score obtained for DM patients from the SMMSE was 21.55±5.7, with 65.3% found to have …
Characteristics And Treatment Outcomes Of Patients With Multi-Drug Resistant Tuberculosis At A Tertiary Care Hospital In Peshawar, Pakistan, Mazhar A. Khan, Sumaira Mehreen, Anila Basit, Raza A. Khan, Faheem Jan, Irfan Ullah, Muhammad Ihtesham, Afsar Khan, Ubaid Ullah, Arshad Javaid
Characteristics And Treatment Outcomes Of Patients With Multi-Drug Resistant Tuberculosis At A Tertiary Care Hospital In Peshawar, Pakistan, Mazhar A. Khan, Sumaira Mehreen, Anila Basit, Raza A. Khan, Faheem Jan, Irfan Ullah, Muhammad Ihtesham, Afsar Khan, Ubaid Ullah, Arshad Javaid
Saudi Medical Journal
Objectives: To determine characteristics and treatment outcomes of multidrugs resistant tuberculosis (MDR-TB) patients and risk factors for poor outcomes in MDR-TB patients in a tertiary care hospital in Peshawar, Pakistan. Methods: This retrospective study was conducted at the Programmatic Management of Drug Resistant TB Unit, Lady Reading Hospital Peshawar, Pakistan and included all MDR-TB patients registered between January 2012 and December 2012. A special proforma was used for data collection. Analysis was performed using SPSS version 16, after exporting data from the proforma. Differences in proportions were assessed using Pearson’s Chi square test whereas for predictors of poor outcomes, multivariate …
Shared Clinical Decision Making: A Saudi Arabian Perspective, Ali I. Alhaqwi, Turki M. Aldrees, Ahmad Alrumayyan, Ali I. Alfarhan, Sultan S. Alotaibi, Hesham I. Alkhashan, Motasim Badri
Shared Clinical Decision Making: A Saudi Arabian Perspective, Ali I. Alhaqwi, Turki M. Aldrees, Ahmad Alrumayyan, Ali I. Alfarhan, Sultan S. Alotaibi, Hesham I. Alkhashan, Motasim Badri
Saudi Medical Journal
Objectives: To determine preferences of patients regarding their involvement in the clinical decision making process and the related factors in Saudi Arabia. Methods: This cross-sectional study was conducted in a major family practice center in King Abdulaziz Medical City, Riyadh, Saudi Arabia, between March and May 2012. Multivariate multinomial regression models were fitted to identify factors associated with patients preferences. Results: The study included 236 participants. The most preferred decision-making style was shared decision-making (57%), followed by paternalistic (28%), and informed consumerism (14%). The preference for shared clinical decision making was significantly higher among male patients and those with higher …
Dental Knowledge Of Educators And Healthcare Providers Working With Children With Autism Spectrum Disorders, Ebtissam Z. Murshid
Dental Knowledge Of Educators And Healthcare Providers Working With Children With Autism Spectrum Disorders, Ebtissam Z. Murshid
Saudi Medical Journal
Objectives: To evaluate dental knowledge and attitudes toward oral health care among healthcare providers and educators working with children with autism spectrum disorders (ASD) in central Saudi Arabia. Methods: There were 305 questionnaires distributed to 7 special-needs centers between September and November 2014. A total of 217 questionnaires were collected with a response rate of 71.1%. The study took place in the College of Dentistry, King Saud University, Riyadh, Kingdom of Saudi Arabia. Results: Approximately 50.2% of the participants did not offer any toothbrushing advice, and 73.3% never recommended dental checkup visits to parents, and 75.6% never performed dental examinations …
Contra-Lateral Shoulder Dislocation Caused By Seat Belts In Drivers And Front-Seat Passengers, Fikri M. Abu-Zidan, Mohamed I. Abusharia, Tomas A. Braunsteiner
Contra-Lateral Shoulder Dislocation Caused By Seat Belts In Drivers And Front-Seat Passengers, Fikri M. Abu-Zidan, Mohamed I. Abusharia, Tomas A. Braunsteiner
Saudi Medical Journal
No abstract provided.
Who Calls On Countries To Protect Health From Climate Change
Who Calls On Countries To Protect Health From Climate Change
Saudi Medical Journal
No abstract provided.
Measles Vaccination Has Saved An Estimated 17.1 Million Lives Since 2000
Measles Vaccination Has Saved An Estimated 17.1 Million Lives Since 2000
Saudi Medical Journal
No abstract provided.
Clinical Utility Of Dabigatran In United Arab Emirates: A Pharmacovigilance Study, Abdulla Shehab, Asim A. Elnour, Adel Sadik, Mahmoud Abu Mandil, Ali Alshamsi, Aesha Al Suwaidi, Akshayasrikanth Bhagavathula, Pinar Erkekoglu, Farah Hamad
Clinical Utility Of Dabigatran In United Arab Emirates: A Pharmacovigilance Study, Abdulla Shehab, Asim A. Elnour, Adel Sadik, Mahmoud Abu Mandil, Ali Alshamsi, Aesha Al Suwaidi, Akshayasrikanth Bhagavathula, Pinar Erkekoglu, Farah Hamad
Saudi Medical Journal
Objectives: To provide early data regarding clinical utility of dabigatran in Al-Ain, United Arab Emirates (UAE). Methods: This was an ethics approved retrospective cross sectional study. We retrieved a total of 76 patients who were using dabigatran from September to December 2014 in the Cardiology Clinic at Al-Ain Hospital, Al-Ain, UAE. The primary analysis was designed to test the frequency of bleeding events (rate) with dabigatran 75, 110, and 150 mg. Results: The mean age ± standard deviation of cohort was 67.9 ± 1.5 years (range; 29-98 years), composed of males (52.6%) with mean age of 66.3 ± 1.7 years, …
Osteoporosis Treatment With Zoledronic Acid In Pediatric Population At A University Hospital In Western Saudi Arabia: A 13-Year Experience, Abdulmoein E. Al-Agha, Rahaf S. Hayatalhazmi
Osteoporosis Treatment With Zoledronic Acid In Pediatric Population At A University Hospital In Western Saudi Arabia: A 13-Year Experience, Abdulmoein E. Al-Agha, Rahaf S. Hayatalhazmi
Saudi Medical Journal
Objectives: To highlight the clinical benefit, efficacy, and safety of zoledronic acid (ZA) therapy in children and adolescents with primary and secondary osteoporosis. Methods: This is a retrospective observational study of 131 children and adolescents visiting the Pediatric Endocrine Clinic at King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia, between January 2002 and January 2015. Clinical and laboratory data were collected for each patient and adverse events were evaluated. Results: The mean patient age was 11.43 years. There was a significant decrease in the number of fractures after ZA treatment for primary osteoporosis ( p =0.000) and in secondary …
A Qualitative Exploration Of The Major Challenges Facing Pharmacovigilance In Saudi Arabia, P. Ravi Shankar, Nisha Jha
A Qualitative Exploration Of The Major Challenges Facing Pharmacovigilance In Saudi Arabia, P. Ravi Shankar, Nisha Jha
Saudi Medical Journal
No abstract provided.
Who/Unicef Report: Malaria Mdg Target Achieved Amid Sharp Drop In Cases And Mortality, But 3 Billion People Remain At Risk
Saudi Medical Journal
No abstract provided.
Prostatic Diseases Under Focus In A University Hospital In Eastern Saudi Arabia: A 15-Year Experience, Reem B. Aldamanhori
Prostatic Diseases Under Focus In A University Hospital In Eastern Saudi Arabia: A 15-Year Experience, Reem B. Aldamanhori
Saudi Medical Journal
Objectives: To explore the spectrum of pathologies diagnosed in prostatic biopsies of Saudi men, and test whether the frequency of diagnosing the malignant fraction has been changed over the last 15 years, and assess the association between chronic inflammation (CI) with both benign prostatic hyperplasia (BPH) and cancer (PCa), and investigate the histological findings of cases presented with acute urinary retention (AUR) clinically. Methods: This is a retrospective cohort study including all prostatic biopsies accessed in the files in the Surgical Pathology Laboratory of King Fahd University Hospital, Alkhobar, Kingdom of Saudi Arabia over 15 years (1999-2013) for Saudi men. …
Who: Number Of People Over 60 Years Set To Double By 2050; Major Societal Changes Required
Who: Number Of People Over 60 Years Set To Double By 2050; Major Societal Changes Required
Saudi Medical Journal
No abstract provided.
Molecular Nature Of Alpha-Globin Genes In The Saudi Population, J. Francis Borgio
Molecular Nature Of Alpha-Globin Genes In The Saudi Population, J. Francis Borgio
Saudi Medical Journal
Alpha-thalassemia (α-thal) is a disorder caused by the deletion of single or double α-globin genes, and/or point mutations in the α-globin genes. There are 2 common types of α-globin genes; HBA2 and HBA1 . Recently, it has been discovered that the HBA2 gene is replaced by a unique HBA12 gene convert in 5.7% of the Saudi population. The α-globin genes have been emerging as a molecular target for the treatment of β-thalassemia (β-thal). Hence, it is essential to understand the molecular nature of α-globin genes to treat the most prevalent hemoglobin disorders, such as sickle cell disease, α-thal, and β-thal …
Can Pre-Implantation Biopsies Predict Renal Allograft Function In Pediatric Renal Transplant Recipients?, Jameela A. Kari, Alison L. Ma, Stephanie Dufek, Ismail Mohamed, Nizam Mamode, Neil J. Sebire, Stephen D. Marks
Can Pre-Implantation Biopsies Predict Renal Allograft Function In Pediatric Renal Transplant Recipients?, Jameela A. Kari, Alison L. Ma, Stephanie Dufek, Ismail Mohamed, Nizam Mamode, Neil J. Sebire, Stephen D. Marks
Saudi Medical Journal
Objectives: To determine the utility of pre-implantation renal biopsy (PIB) to predict renal allograft outcomes. Methods: This is a retrospective review of all patients that underwent PIB from January 2003 to December 2011 at the Great Ormond Street Hospital for Children in London, United Kingdom. Thirty-two male patients (56%) aged 1.5-16 years (median: 10.2) at the time of transplantation were included in the study and followed-up for 33 (6-78) months. The results were compared with 33 controls. Results: The PIB showed normal histopathological findings in 13 patients (41%), mild chronic vascular changes in 8 (25%), focal tubular atrophy in one, …
Favorable Therapeutic Response Of Osteoporosis Patients To Treatment With Intravenous Zoledronate Compared With Oral Alendronate, Mohammed M. Al-Bogami, Mohammed A. Alkhorayef, Jonas Bystrom, Olufunso A. Akanle, Nasra K. Al-Adhoubi, Ali S. Jawad, Rizgar A. Mageed
Favorable Therapeutic Response Of Osteoporosis Patients To Treatment With Intravenous Zoledronate Compared With Oral Alendronate, Mohammed M. Al-Bogami, Mohammed A. Alkhorayef, Jonas Bystrom, Olufunso A. Akanle, Nasra K. Al-Adhoubi, Ali S. Jawad, Rizgar A. Mageed
Saudi Medical Journal
Objectives: To evaluate the efficacy of orally-administered alendronate compared with intravenously-administered zoledronate. Methods: This prospective study was carried out at Barts Health HNS Trust between April 2010 and March 2012. This study compares changes in bone mineral density (BMD) in 234 patients treated with 2 bisphosphonates: alendronate taken orally, and zoledronate administered intravenously. One hundred and eighteen patients received alendronate at 70 mg/week, while 116 patients received zoledronate once annually. Dual energy x-ray absorptiometry was used to measure BMD of the left hip and anterior-posterior spine (lumbar L1-L4) skeletal sites at baseline, and at one-, and 2-years post-treatment. Results: This …
Decline In Menarcheal Age Among Saudi Girls, Areej A. Ibrahim, Motasim A. Badri, Bassam S. Bin-Abbas
Decline In Menarcheal Age Among Saudi Girls, Areej A. Ibrahim, Motasim A. Badri, Bassam S. Bin-Abbas
Saudi Medical Journal
Objectives: To estimate age at menarche and to assess trends in menarcheal age among Saudi women. Methods: A prospective longitudinal study was conducted among healthy prepubertal female school children and adolescents from September 2006 to July 2012 in Riyadh, Kingdom of Saudi Arabia. Study participants were invited from diverse socioeconomic backgrounds. Tanner stage, height, weight, body mass index, and socioeconomic parameters including parent’s level of education were collected. Age at menarche was compared with maternal age at menarche. Results: The study included 265 girls and mothers. Mean±standard deviation (SD) age at menarche for girls was 13.08 ± 1.1 years, and …
Perception Of The Faculty Regarding Problem-Based Learning As An Educational Approach In Northwestern Saudi Arabia, Moutasem Aboonq
Perception Of The Faculty Regarding Problem-Based Learning As An Educational Approach In Northwestern Saudi Arabia, Moutasem Aboonq
Saudi Medical Journal
Objectives: To assess the knowledge, attitudes, and practice of medical teachers regarding problem-based learning (PBL) in Northwestern Saudi Arabia. Methods: This is a cross-sectional study conducted in the College of Medicine, Taibah University, Al Madinah Al Munawarah, Kingdom of Saudi Arabia, at the beginning of the academic year 2014/2015 where the PBL method had recently been introduced. Medical academic staff (n=110) were invited to participate in the study. Data about staff sociodemographic characteristics, PBL knowledge, attitudes, and practice were collected via a pre-designed structured questionnaire. The collected data were analyzed using appropriate statistical methods. Results: The overall response rate was …
Effectiveness Of Benzocaine In Reducing Deep Cavity Restoration And Post-Extraction Stress In Dental Patients, Khalid H. Al-Samadani, Giath Gazal
Effectiveness Of Benzocaine In Reducing Deep Cavity Restoration And Post-Extraction Stress In Dental Patients, Khalid H. Al-Samadani, Giath Gazal
Saudi Medical Journal
Objectives: To investigate the effectiveness of topical anesthetic, 20% benzocaine in relieving pain and stress in patients following deep cavity restoration and extraction of teeth under local anesthesia (LA). Methods: A prospective clinical trial was conducted from October 2014 until April 2015 at Taibah University, Al Madinah Al Munawarah, Kingdom of Saudi Arabia. Forty-five patients were included in the 20% benzocaine group, and 46 in the normal saline group. Evaluation of the dental stress was made pre-operatively and immediately post-operative treatment using the visual analogue scale (VAS). Furthermore, discomfort of the injections were recorded by the patients after each treatment …
Glutaric Aciduria Type 1 As A Cause Of Dystonic Cerebral Palsy, Sarar Mohamed, Muddathir H. Hamad, Hamdy H. Hassan, Mustafa A. Salih
Glutaric Aciduria Type 1 As A Cause Of Dystonic Cerebral Palsy, Sarar Mohamed, Muddathir H. Hamad, Hamdy H. Hassan, Mustafa A. Salih
Saudi Medical Journal
Glutaric aciduria type 1 (GA1) is an inherited inborn error of metabolism caused by a deficiency of the enzyme glutaryl Co-A dehydrogenase (GCDH). Here, we report a 14-month-old Saudi boy with GA1 who presented with severe dystonia and was mis-diagnosed as cerebral palsy (CP). He presented to our institute with encephalopathy following an episode of gastroenteritis. His physical examination showed dystonia and spastic quadriplegia. His investigations revealed elevated both urinary 3-hydroxy glutaric acid, and serum glutarylcarnitine. The DNA analysis confirmed homozygosity for a mutation in the GCDH-coding gene (c.482G>A;p.R161Q). This case alerts pediatricians to consider GA1 as a differential …
Diagnostic Accuracy Of Coronary Angiography Using 64-Slice Computed Tomography In Coronary Artery Disease, Fu-Bin Yang, Wan-Liang Guo, Mao Sheng, Ling Sun, Yue-Yue Ding, Qiu-Qin Xu, Ming-Guo Xu, Hai-Tao Lv
Diagnostic Accuracy Of Coronary Angiography Using 64-Slice Computed Tomography In Coronary Artery Disease, Fu-Bin Yang, Wan-Liang Guo, Mao Sheng, Ling Sun, Yue-Yue Ding, Qiu-Qin Xu, Ming-Guo Xu, Hai-Tao Lv
Saudi Medical Journal
Objectives: To conduct a meta-analysis and investigate the diagnostic value of 64-slice computed tomography (CT) angiography for diagnosing coronary artery disease (CAD) in patients. Methods: A comprehensive literature search from March 2005 to August 2014 was performed on the following databases: Cochrane Library; Medline; EmBase; PubMed; and BioMed Central database. As a reference standard, studies that assessed 64-slice CT angiography in detecting coronary artery stenosis (CAS) with invasive coronary angiography were included. Coronary artery stenosis was defined as ≥50% diameter stenosis. Diagnostic value was determined by pooling sensitivity, specificity, positive likelihood ratio (PLR) and negative likelihood ratio (NLR) values at …