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Evaluation Of Genexpert Mtb/Rif For Detection Of Mycobacterium Tuberculosis Complex And Rpo B Gene In Respiratory And Non-Respiratory Clinical Specimens At A Tertiary Care Teaching Hospital In Saudi Arabia, Ali M. Somily, Mazin A. Barry, Hanan A. Habib, Fawzia E. Alotaibi, Fahad A. Al-Zamil, Mohammed A. Khan, Mohammed S. Sarwar, Nawab D. Bakhash, Abdulkarim A. Alrabiaah, Zahid A. Shakoor, Abiola C. Senok
Evaluation Of Genexpert Mtb/Rif For Detection Of Mycobacterium Tuberculosis Complex And Rpo B Gene In Respiratory And Non-Respiratory Clinical Specimens At A Tertiary Care Teaching Hospital In Saudi Arabia, Ali M. Somily, Mazin A. Barry, Hanan A. Habib, Fawzia E. Alotaibi, Fahad A. Al-Zamil, Mohammed A. Khan, Mohammed S. Sarwar, Nawab D. Bakhash, Abdulkarim A. Alrabiaah, Zahid A. Shakoor, Abiola C. Senok
Saudi Medical Journal
Objectives To assess the performance of Xpert MTB/RIF, an automated molecular test for Mycobacterium tuberculosis (MTB) and resistance to rifampin (RIF), against smear microscopy and culture method for diagnosis of MTB infection. Methods This is a retrospective analysis of 103 respiratory and 137 non-respiratory patient specimens suspected of tuberculosis at King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia performed between April 2014 and March 2015. Each sample underwent smear microscopy, mycobacterial culture, and GeneXpert MTB/RIF test. Results Fifteen out of 103 respiratory samples were smear and culture positive, whereas 9 out of 137 non-respiratory samples were smear positive. Out …
Microvascular And Macrovascular Complications Of Type 2 Diabetic Mellitus In Central, Kingdom Of Saudi Arabia, Aboud F. Alaboud, Ayla M. Tourkmani, Turki J. Alharbi, Aljoharah H. Alobikan, Osama Abdelhay, Hesham I. Alkhashan, Umar Y. Mohammed
Microvascular And Macrovascular Complications Of Type 2 Diabetic Mellitus In Central, Kingdom Of Saudi Arabia, Aboud F. Alaboud, Ayla M. Tourkmani, Turki J. Alharbi, Aljoharah H. Alobikan, Osama Abdelhay, Hesham I. Alkhashan, Umar Y. Mohammed
Saudi Medical Journal
Objectives To determine the prevalence of macrovascular and microvascular complications of type 2 diabetes mellitus and its associated determinants. Methods We evaluated the online medical records of patients with type 2 diabetes mellitus who have been seen in chronic disease unit between April and June 2014. Seven hundred and forty-eight participants satisfied the inclusion criteria. Of these, 317 (42.4%) were males with a mean age of 57.9 years, 681 (64.3%) were obese with body mass index (BMI) of greater than 30, while only 9.6% had normal BMI (<25). Results Only 158 (21.1%) had controlled hemoglobin A1c level. Retinopathy prevalence was 14.8% and neuropathy was 5.6%. Macrovascular complications accounted for 12.1%. Patients’ age and duration of diabetes were main predictors of developing complications. Patients with more than 20 years history of diabetes have 30% more odds of developing the complications when compared to patients with less than 10 years of diabetes history. Each increment in age by one year increases the odds of developing microvascular complications by 4% and macro vascular complication by 2%. Conclusion Our results showed diabetic patients with poor glycemic control, and longer duration of diabetic history had higher prevalence of both macrovascular and microvascular.
Emerging Zika Virus, Sora Yasri, Viroj Wiwanitkit
Emerging Zika Virus, Sora Yasri, Viroj Wiwanitkit
Saudi Medical Journal
No abstract provided.
Family Profile Of Victims Of Child Abuse And Neglect In The Kingdom Of Saudi Arabia, Ghulam Nabi
Family Profile Of Victims Of Child Abuse And Neglect In The Kingdom Of Saudi Arabia, Ghulam Nabi
Saudi Medical Journal
No abstract provided.
Who Recommends 29 Ways To Stop Surgical Infections And Avoid Superbugs
Who Recommends 29 Ways To Stop Surgical Infections And Avoid Superbugs
Saudi Medical Journal
No abstract provided.
Over 1 Million Treated With Highly Effective Hepatitis C Medicines
Over 1 Million Treated With Highly Effective Hepatitis C Medicines
Saudi Medical Journal
No abstract provided.
Distribution Of Various Pathogenic Bacteria From Pediatric Ward Settings, Irfan A. Butt, Bilal Aslam, Muhammad H. Rasool, Humerah B. Shafiq, Mohsin Khurshid, Muhammad A. Aslam
Distribution Of Various Pathogenic Bacteria From Pediatric Ward Settings, Irfan A. Butt, Bilal Aslam, Muhammad H. Rasool, Humerah B. Shafiq, Mohsin Khurshid, Muhammad A. Aslam
Saudi Medical Journal
Objectives: To test various items in hospital environment as reservoirs of bacteria. Methods: This simple descriptive study was conducted between June and December 2014. Pediatric wards of 4 different hospitals of Faisalabad, Pakistan were selected and 8 different items per hospital were sampled (n=160). Poisson regression analysis was carried out with R software and using lme4 package. Results: There were no differences between the hospitals regarding total number of bacterial isolates or bacterial isolates per sample source or prevalent bacterial species. Utensile tables were significantly the least contaminated source when comparing all sample sources from all hospitals ( p =0.05). …
To What Extent Should Dental Implant Placement Be Adopted As A Standard For Diabetic Patients?, Ahmed S. Alzahrani, Hassan H. Abed
To What Extent Should Dental Implant Placement Be Adopted As A Standard For Diabetic Patients?, Ahmed S. Alzahrani, Hassan H. Abed
Saudi Medical Journal
Diabetes mellitus (DM) is considered one of the major chronic diseases in the world. Long-term hyperglycemia considerably affects the body tissues, and consequently, can lead to morbidity and mortality. Moreover, many oral complications have been observed with DM but little consideration in relation to the placement of dental implants has been investigated. Dental research has analyzed the relation of dental implants and bone osseointegration in diabetic patients. Theoretically, an impaired immune system and delayed wound healing of these patients might decrease the success rate of implant placement; however, with noticeable advances in evidence-based dentistry and statistically significant results, successful implant …
Tall Cell Variant Papillary Thyroid Carcinoma In Saudi Patients: A Clinicopathological And Outcomes Analysis, Khalid H. Al-Qahtani, Mutahir A. Tunio, Mushabbab Al Asiri, Yasser Bayoumi, Walaa A. Alshehri, Naji J. Aljohani, Ahmed Amir Ali, Hanadi Fatani
Tall Cell Variant Papillary Thyroid Carcinoma In Saudi Patients: A Clinicopathological And Outcomes Analysis, Khalid H. Al-Qahtani, Mutahir A. Tunio, Mushabbab Al Asiri, Yasser Bayoumi, Walaa A. Alshehri, Naji J. Aljohani, Ahmed Amir Ali, Hanadi Fatani
Saudi Medical Journal
Objectives: To evaluate the clinicopathological features and treatment outcomes of papillary thyroid carcinoma tall cell variant (PTC-TCV) in Saudi population. Methods: This retrospective study were medical records of 776 treated PTC patients between December 2007 and 2015, at King Fahad Medical City and King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia was probed for PTC-TCV. Total 42 (5.4%) patients were found to have PTC-TCV, which were investigated for demographic, symptoms, histopathological features, and treatment outcomes locoregional control (LRC), distant metastasis control (DMC), disease free survival (DFS), and overall survival (OS) rates. Results: Mean age of cohort was 52.3 years …
Diverse Etiology Of Hyperlipidemia Among Hospitalized Children In Western Region Of Saudi Arabia, Abdulmoein E. Al-Agha, Abrar M. Alnawab, Tala M. Hejazi
Diverse Etiology Of Hyperlipidemia Among Hospitalized Children In Western Region Of Saudi Arabia, Abdulmoein E. Al-Agha, Abrar M. Alnawab, Tala M. Hejazi
Saudi Medical Journal
Objectives: To determine the various etiologies of primary and secondary hyperlipidemia among children visiting the pediatric endocrine clinic. Methods: This is a retrospective, cross-sectional, cohort study conducted at King Abdulaziz University Hospital (KAUH), Jeddah, Kingdom of Saudi Arabia from January 2010 to 2015 that included 253 children aged from birth to 12 years old. Data were obtained by reviewing medical reports of patients who presented with hyperlipidemia to the clinic, and their laboratory investigation results using KAUH electronic “Phoenix” system. Results: Of the 253 children who were reviewed, those who have shown to have abnormal lipid metabolism with nephrotic syndrome …
In This Issuesystematic Revieworiginal Articlescase Report
In This Issuesystematic Revieworiginal Articlescase Report
Saudi Medical Journal
No abstract provided.
Erlotinib For Advanced Hepatocellular Carcinoma: A Systematic Review Of Phase Ii/Iii Clinical Trials, Jing Zhang, Yuan Zong, Gang-Zhu Xu, Ke Xing
Erlotinib For Advanced Hepatocellular Carcinoma: A Systematic Review Of Phase Ii/Iii Clinical Trials, Jing Zhang, Yuan Zong, Gang-Zhu Xu, Ke Xing
Saudi Medical Journal
Objectives: To evaluate the efficacy and safety of erlotinib for the treatment of advanced hepatocellular carcinoma (HCC). Methods: A systematic literature search was undertaken in June 2015. Phase II/III trials of erlotinib for the treatment of advanced HCC were included. A descriptive analysis was applied. The study was conducted in College of Medicine, Honghui Hospital, Xi’an Jiaotong University, Xi’an, China, between June 2015 and January 2016. Results: Ten trials, comprising 9 phase II and one phase III trial, were included in the systematic review. The tumor response rate was 0% in 4 of the phase II trials, <10% in 3 of the phase II trials and the phase III trial, and >20% in 2 …
Alfentanil Versus Ketamine Combined With Propofol For Sedation During Upper Gastrointestinal System Endoscopy In Morbidly Obese Patients, Ertugrul Kılıc, Barıs Demiriz, Nurgül Isıkay, Abdullah E. Yıldırım, Selman Can, Cem Basmacı
Alfentanil Versus Ketamine Combined With Propofol For Sedation During Upper Gastrointestinal System Endoscopy In Morbidly Obese Patients, Ertugrul Kılıc, Barıs Demiriz, Nurgül Isıkay, Abdullah E. Yıldırım, Selman Can, Cem Basmacı
Saudi Medical Journal
Objectives: To observe the effects of both propofol/alfentanil and propofol/ketamine on sedation during upper gastrointestinal system endoscopy in morbidly obese patients (UGSEMOP). Methods: In a prospective, double-blinded, randomized clinical study, 52 patients scheduled for UGSEMOP were assigned to either group A (n=26; 10 µg/kg intravenous [IV] alfentanil) or group K (n=26; 0.5 mg/kg IV ketamine). Each patient was administered 0.7 mg/kg propofol for induction. If it was needed, the patients were administered an additional dose of IV propofol. This study was performed in Sehitkamil State Hospital, Gaziantep, Turkey, between January 2014-2015. Total propofol consumption, time to achieve Modified Aldrete Scores …
A Profile Of Out-Of-Hospital Cardiac Arrests In Northern Emirates, United Arab Emirates, Alan M. Batt, Ahmed S. Al-Hajeri, Fergal H. Cummins
A Profile Of Out-Of-Hospital Cardiac Arrests In Northern Emirates, United Arab Emirates, Alan M. Batt, Ahmed S. Al-Hajeri, Fergal H. Cummins
Saudi Medical Journal
Objectives: To report the characteristics of out-of-hospital cardiac arrest patients and their outcomes in the emirates of Sharjah, Ras-al-Khaimah, Umm Al-Quwain, Fujairah, and Ajman in the United Arab Emirates (collectively known as the Northern Emirates). Methods: This is a prospective descriptive cohort study of out-of-hospital cardiac arrest incidents transported by the national ambulance crews between February 2014 and March 2015 in the Northern Emirates. Results: A total of 384 patients were enrolled in this study. Male victims of out-of-hospital cardiac arrest represented 76% of the participants. The mean age of the study population was 50.9 years. An over-all prehospital return …
Lung Cancer In Basrah, Iraq During 2005-2012: Incidence And Time Trend, Omran S. Habib, Jasim N. Al-Asadi, Osama G. Hussien
Lung Cancer In Basrah, Iraq During 2005-2012: Incidence And Time Trend, Omran S. Habib, Jasim N. Al-Asadi, Osama G. Hussien
Saudi Medical Journal
Objectives: To study the incidence rate of lung cancer and its time trend in Basrah during 2005-2012. Methods: This was a cancer registry-based retrospective study including all Basrah inhabitant patients diagnosed with primary lung cancer during the period from January 2005 to December 2012. The crude incidence rate was calculated in addition to the age standardized incidence rate (ASIR)/100,000 using the world standard population. Results: Out of 746 registered cases of lung cancer in Basrah, 75.9% were males and 24.1% were females with a male: female gender ratio of 3.1:1. The crude incidence rate was 3.93/100,000 (5.89/100,000 for males and …
Low Bone Mineral Density Among Young Healthy Adult Saudi Women: Prevalence And Associated Factors In The Age Group Of 20 To 36 Years, Zeidan A. Zeidan, Intisar E. Sultan, Shaista S. Guraya, Abdulmohsen H. Al-Zalabani, Khalid I. Khoshhal
Low Bone Mineral Density Among Young Healthy Adult Saudi Women: Prevalence And Associated Factors In The Age Group Of 20 To 36 Years, Zeidan A. Zeidan, Intisar E. Sultan, Shaista S. Guraya, Abdulmohsen H. Al-Zalabani, Khalid I. Khoshhal
Saudi Medical Journal
Objectives: To screen for low bone mineral density among young adult Saudi women using quantitative ultrasound (QUS) and exploring the high risk groups. Methods: A cross-sectional study was performed on 279, 20-36 years old female students and employees of Taibah University, Al Madinah Al Munawwarah, Kingdom of Saudi Arabia between January and May 2014. The study included bone status assessed using QUS, a structured self-reported questionnaire, anthropometric measurements, and evaluation of bone markers of bone metabolism. Results: The prevalence of low bone mineral density was 9%. Serum osteocalcin was found significantly higher in candidates with low bone mineral density, 20.67 …
Effect Of Iron Overload On Renal Functions And Oxidative Stress In Beta Thalassemia Patients, Mahmood Rasool, Arif Malik, Uzma Jabbar, Irshad Begum, Mahmood H. Qazi, Muhammad Asif, Muhammad I. Naseer, Shakeel A. Ansari, Jummanah Jarullah, Absarul Haque, Mohammad S. Jamal
Effect Of Iron Overload On Renal Functions And Oxidative Stress In Beta Thalassemia Patients, Mahmood Rasool, Arif Malik, Uzma Jabbar, Irshad Begum, Mahmood H. Qazi, Muhammad Asif, Muhammad I. Naseer, Shakeel A. Ansari, Jummanah Jarullah, Absarul Haque, Mohammad S. Jamal
Saudi Medical Journal
Objectives: To check the amount of cellular damage caused by serial transfusions of blood in thalassemia patients. Methods: A cross-sectional study was conducted in the University of Lahore, Lahore, Pakistan between August 2012 and December 2012. A total of 43 thalassemia patients underwent at least 10 blood transfusions. Comprehensive biochemical analysis of blood was performed to record the levels of creatinine, urea, uric acid, albumin, liver function tests, malondialdehyde (MDA), and ferritin. Results: Serum creatinine (0.732±0.23mg/dl) and uric acid (6.7±0.94mg/dl, p <0.05) were significantly higher in patient groups as compared with the control. Ferritin levels were significantly higher in patients as compared with the control (3103.9±1747.4, p <0.05). Hemoglobin levels were observed in controls 14±1.3g/dl and in patients 7.1±1.03g/dl. No clear relationship exists between age and hematological parameters of thalassemic patients. Serum ferritin level is positively related with serum alanine transaminase, aspartate aminotransferase, and alkaline phosphatase and MDA ( p <0.05). Conclusion: Serum MDA and serum ferritin of patients (r=0.593, p <0.05) reflects that both are crucial parameters estimating the cellular damage in patients suffering from thalassemia.
Physical Activity And Major Non-Communicable Diseases Among Physicians In Central Saudi Arabia, Ahmed M. Mandil, Nuha A. Alfurayh, Manar A. Aljebreen, Sarah A. Aldukhi
Physical Activity And Major Non-Communicable Diseases Among Physicians In Central Saudi Arabia, Ahmed M. Mandil, Nuha A. Alfurayh, Manar A. Aljebreen, Sarah A. Aldukhi
Saudi Medical Journal
Objectives: To evaluate levels of physical activity among physicians in Riyadh, Saudi Arabia and to study the possible factors affecting physical inactivity. In addition, the study aims to estimate the prevalence of major non-communicable diseases (NCDs) and a possible correlation between physical inactivity and major NCDs. Method: A cross-sectional approach was used for this study conducted on 370 randomly-selected outpatient physicians of both genders working at 4 leading healthcare institutions in Riyadh, Kindom of Saudi Arabia between December 2013 and January 2014. Using a modified World Health Organization (WHO) STEPwise questionnaire. Data was analyzed using the Statistical Package for Social …
Institute For Scientific Information-Indexed Biomedical Journals Of Saudi Arabia: Their Performance From 2007-2014, Dileep K. Rohra, Vikram K. Rohra, Peter Cahusac
Institute For Scientific Information-Indexed Biomedical Journals Of Saudi Arabia: Their Performance From 2007-2014, Dileep K. Rohra, Vikram K. Rohra, Peter Cahusac
Saudi Medical Journal
Objectives: To compare the journal impact factor (JIF) and Eigenfactor score (ES) of Institute for Scientific Information (ISI)-indexed biomedical journals published from the Kingdom of Saudi Arabia (KSA) over the last 8 years. Methods: This is a retrospective study, conducted at Alfaisal University, Riyadh, KSA from January to March 2016. The Journal Citation Reports of ISI Web of Knowledge were accessed, and 6 Saudi biomedical journals were included for analysis. Results: All Saudi journals have improved their IF compared with their baseline. However, the performance of the Journal of Pharmaceutical Sciences and Neurosciences has been exceptionally good. The biggest improvement …
The Significance Of Anthropometric And Endocrine Parameters In Ovulation Induction With Clomiphene Citrate In Women With Polycystic Ovary Syndrome, Funda Akpinar, Berna Dilbaz, Derya A. Cirik, Saynur Yılmaz, Sadıman Kıykac, Ertugrul Karahanoglu, Leyla Mollamahmutoglu
The Significance Of Anthropometric And Endocrine Parameters In Ovulation Induction With Clomiphene Citrate In Women With Polycystic Ovary Syndrome, Funda Akpinar, Berna Dilbaz, Derya A. Cirik, Saynur Yılmaz, Sadıman Kıykac, Ertugrul Karahanoglu, Leyla Mollamahmutoglu
Saudi Medical Journal
Objectives: To investigate factors associated with the response to ovarian stimulation in patients with polycystic ovary syndrome. Methods: The records of patients with polycystic ovary syndrome and infertility who underwent ovulation induction with clomiphene citrate were reviwed between January 2011 and December 2014 in Etlik Zübeyde Hanim Women’s Health Training and Research Hospital Ankara, Turkey. The anthropometric and endocrine factors of patients who were resistant to treatment at a dose of 150 mg/day (n=84) were compared with those who responded with growth of at least one graaffian follicle at a dose of 50 mg/day (n=342). Results: Of the parameters examined, …
The Saudi Clinical Practice Guideline For The Prophylaxis Of Venous Thromboembolism In Medical And Critically Ill Patients, Fahad M. Al-Hameed, Hasan M. Al-Dorzi, Mohamed A. Abdelaal, Ali Alaklabi, Ebtisam Bakhsh, Yousef A. Alomi, Mohammad Al Baik, Salah Aldahan, Holger Schünemann, Jan Brozek, Wojtek Wiercioch, Andrea J. Darzi, Reem Waziry, Elie A. Akl
The Saudi Clinical Practice Guideline For The Prophylaxis Of Venous Thromboembolism In Medical And Critically Ill Patients, Fahad M. Al-Hameed, Hasan M. Al-Dorzi, Mohamed A. Abdelaal, Ali Alaklabi, Ebtisam Bakhsh, Yousef A. Alomi, Mohammad Al Baik, Salah Aldahan, Holger Schünemann, Jan Brozek, Wojtek Wiercioch, Andrea J. Darzi, Reem Waziry, Elie A. Akl
Saudi Medical Journal
Venous thromboembolism (VTE) acquired during hospitalization is common, yet preventable by the proper implementation of thromboprophylaxis which remains to be underutilized worldwide. As a result of an initiative by the Saudi Ministry of Health to improve medical practices in the country, an expert panel led by the Saudi Association for Venous Thrombo Embolism (SAVTE; a subsidiary of the Saudi Thoracic Society) with the methodological guidance of the McMaster University Guideline working group, produced this clinical practice guideline to assist healthcare providers in VTE prevention. The expert part panel issued ten recommendations addressing 10 prioritized questions in the following areas: thromboprophylaxis …
Cochrane Review: Conclusions About The Effects Of Electronic Cigarettes Remain The Same
Cochrane Review: Conclusions About The Effects Of Electronic Cigarettes Remain The Same
Saudi Medical Journal
No abstract provided.
Who Urges Global Action To Curtail Consumption And Health Impacts Of Sugary Drinks
Who Urges Global Action To Curtail Consumption And Health Impacts Of Sugary Drinks
Saudi Medical Journal
No abstract provided.
Who Calls For Immediate Safe Evacuation Of The Sick And Wounded From Conflict Areas: Who Is Also Calling For A Halt Of Attacks On Health Care Workers And Facilities
Saudi Medical Journal
No abstract provided.
Impact Of Rehabilitation Programs On Dependency And Functional Performance Of Patients With Major Lower Limb Amputations: A Retrospective Chart Review In Western Saudi Arabia, Mohammad A. Alsofyani, Abdulaziz S. Alharthi, Fayssal M. Farahat, Wesam T. Abuznadah
Impact Of Rehabilitation Programs On Dependency And Functional Performance Of Patients With Major Lower Limb Amputations: A Retrospective Chart Review In Western Saudi Arabia, Mohammad A. Alsofyani, Abdulaziz S. Alharthi, Fayssal M. Farahat, Wesam T. Abuznadah
Saudi Medical Journal
Objectives: To determine pattern and impact of physical rehabilitation on dependency and functional performance of patients. Methods: This retrospective chart review was carried out between July and August 2012 at King Abdulaziz Medical City, Jeddah, Saudi Arabia. Data were collected using demographic, clinical, and dependency assessment checklists. Results: Patients who underwent major lower limb amputations between January 2007 and April 2012 (n=121) were included in the study. There were 84 (69.4%) male and 37 (30.6%) female patients with a mean ± standard deviation of 63.3±17.4 years old. Diabetes mellitus was the most frequent cause in 63.6% of patients. Only one-third …
The Role Of Geriatric Assessment Tests And Anthropometric Measurements In Identifying The Risk Of Falls In Elderly Nursing Home Residents, Bulent Yardimci, Sinan N. Aran, Ismail Ozkaya, Sevki M. Aksoy, Tarik Demir, Gulsen Tezcan, Aysegul Y. Kaptanoglu
The Role Of Geriatric Assessment Tests And Anthropometric Measurements In Identifying The Risk Of Falls In Elderly Nursing Home Residents, Bulent Yardimci, Sinan N. Aran, Ismail Ozkaya, Sevki M. Aksoy, Tarik Demir, Gulsen Tezcan, Aysegul Y. Kaptanoglu
Saudi Medical Journal
Objectives: To determine the relation among the risk of falls, geriatric assessment, and anthropometric measurements, including the mini mental state examination, geriatric depression scale, handgrip test, and key pinch test. Methods: This prospective study included 89 residents hospitalized between May 2014 and September 2015 in the geriatric care unit of the Istanbul Balikli Rum Hospital, Istanbul, Turkey. Patients were followed-up for one year, and their falls were recorded. Medical records of the included patients were retrieved and analyzed. Results: A total of 89 patients, comprising 37 men and 52 women with an average age of 75.8 ± 8.2 years were …
Effects Of Nicotine On Bone During Orthodontic Tooth Movement In Male Rats: Histological And Immunohistochemical Study, Manal A. Bakathir, Amal I. Linjawi, Samia S. Omar, Ahad B. Aboqura, Ali H. Hassan
Effects Of Nicotine On Bone During Orthodontic Tooth Movement In Male Rats: Histological And Immunohistochemical Study, Manal A. Bakathir, Amal I. Linjawi, Samia S. Omar, Ahad B. Aboqura, Ali H. Hassan
Saudi Medical Journal
Objectives: To investigate the effects of nicotine on orthodontic tooth movement and accompanying histological and immunohistochemical changes in rats. Methods: An experimental study conducted at King Abdulaziz University, Jeddah, Saudi Arabia between 2013 and 2014. Thirty-two rats randomly divided into 4 groups. Three were experimental, received daily nicotine injections: group A: 0.37 mg/kg, group B: 0.57 mg/kg, and group C: 0.93 mg/kg. The control group (group D) received a daily injection of 0.5 mL saline. All rats were subjected to 30 g of orthodontic force on the maxillary left first molars and incisors using a nickel-titanium closed-coil spring. The distance …
Do Statins Really Cause Diabetes?: A Meta-Analysis Of Major Randomized Controlled Clinical Trials, Alaa J. Rahal, Ahmed I. Elmallah, Rita J. Poushuju, Rana Itani
Do Statins Really Cause Diabetes?: A Meta-Analysis Of Major Randomized Controlled Clinical Trials, Alaa J. Rahal, Ahmed I. Elmallah, Rita J. Poushuju, Rana Itani
Saudi Medical Journal
Objectives: To investigate and establish the relationship between the use of statin therapy and the risk of development of diabetes. Methods: PubMed and the Cochrane Central Register of Controlled Trials was searched for randomized controlled end-point trials of statins, with more than 1000 subjects and a minimum of one-year follow-up period, published until August 2015. The odds ratio (OR) of diabetes incidence with overall statin therapy as well as with different statins in question was calculated through random effect meta-analysis model. Results: Fourteen studies were included in the analysis with a total of 94,943 participants. Of these, 2392 subjects developed …
Leaders Produce Leaders And Managers Produce Followers: A Systematic Review Of The Desired Competencies And Standard Settings For Physicians’ Leadership, Khalid I. Khoshhal, Salman Y. Guraya
Leaders Produce Leaders And Managers Produce Followers: A Systematic Review Of The Desired Competencies And Standard Settings For Physicians’ Leadership, Khalid I. Khoshhal, Salman Y. Guraya
Saudi Medical Journal
Objectives: To elaborate the desired qualities, traits, and styles of physician’s leadership with a deep insight into the recommended measures to inculcate leadership skills in physicians. Methods: The databases of MEDLINE, EMBASE, CINAHL, and the Cochrane Library were searched for the full-text English-language articles published during the period 2000-2015. Further search, including manual search of grey literature, was conducted from the bibliographic list of all included articles. Medical Subject Headings (MeSH) keywords “Leadership” AND “Leadership traits” AND “Leadership styles” AND “Physicians’ leadership” AND “Tomorrow’s doctors” were used for the literature search. This search followed a step-wise approach defined by the …
A Novel Missense Mutation In The C2c Domain Of Otoferlin Causes Profound Hearing Impairment In An Omani Family With Auditory Neuropathy, Nadia M. Al-Wardy, Mohammed N. Al-Kindi, Mazin J. Al-Khabouri, Yahya Tamimi, Guy Van Camp
A Novel Missense Mutation In The C2c Domain Of Otoferlin Causes Profound Hearing Impairment In An Omani Family With Auditory Neuropathy, Nadia M. Al-Wardy, Mohammed N. Al-Kindi, Mazin J. Al-Khabouri, Yahya Tamimi, Guy Van Camp
Saudi Medical Journal
Objectives: To identify genetic defects in an Omani family diagnosed with deafness. Methods: A cross-sectional association study was conducted at the Department of Biochemistry, College of Medicine and Health Sciences, Sultan Qaboos University, Al-Khoud, Oman and the Centre of Medical Genetics, University of Antwerp, Antwerp, Belgium between August 2010 and September 2014. Microsatellites markers for nine non-syndromic genes were used to genotype the defective locus using the extracted DNA from family members. Sanger sequencing method was used to identify the disease causative mutation. Eazy linkage 5.05 was used to calculate the logarithm of odds score. Lasergene suite was used to …