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Risk Factors And Clinical Outcomes Of Abnormal Placental Localization: A Comprehensive Retrospective Analysis, Bessy Varghese, Alia Abdulla Abdullatif, Yusuf Khaled Hadi, Noor Ammar Alkhuzaei, Khawla Al Sendy, Marwa Abdulrahman Juma Salem, Youstina Georges, Amala Sunder Mar 2026

Risk Factors And Clinical Outcomes Of Abnormal Placental Localization: A Comprehensive Retrospective Analysis, Bessy Varghese, Alia Abdulla Abdullatif, Yusuf Khaled Hadi, Noor Ammar Alkhuzaei, Khawla Al Sendy, Marwa Abdulrahman Juma Salem, Youstina Georges, Amala Sunder

Saudi Medical Journal

Objectives: To evaluate maternal and neonatal complications associated with various types of placental abnormal localization. Methods: This retrospective study analysed obstetric and neonatal outcomes associated with placental abnormal localization at Bahrain Defence Force Hospital over a 12-month period (January–December 2022). Women were categorized into four groups based on placental localization: placenta previa with accreta, placenta previa with increta, minor previa, and major previa. Maternal demographics, obstetric history, and fetal outcomes were collected. Statistical analysis included Fisher's exact test for categorical variables, the Kruskal-Wallis test for non-parametric variables, and one-way ANOVA for parametric variables. A p-value of Results: A total …


Impact Of Nursing Program Structure On Academic Stress Levels And Self-Concept: A Cross-Sectional Study Of Nursing Students' Experiences With 2- And 3-Semester Academic Calendars, Alaa Ayyadhah Alanazi, Amany Anwar Saeed Alabdullah, Hanan Hamdanalshehri, Abrar M. Almutairi Mar 2026

Impact Of Nursing Program Structure On Academic Stress Levels And Self-Concept: A Cross-Sectional Study Of Nursing Students' Experiences With 2- And 3-Semester Academic Calendars, Alaa Ayyadhah Alanazi, Amany Anwar Saeed Alabdullah, Hanan Hamdanalshehri, Abrar M. Almutairi

Saudi Medical Journal

Objective: To investigate undergraduate nursing students' perceptions of their transition from a 2-semester to a 3-semester academic calendar and examine its impact on academic stress and self-concept. Methods: A cross-sectional study was conducted between April and December 2023 among 185 undergraduate nursing students in Saudi Arabia who had completed at least their foundational year. Participants completed an online questionnaire containing Likert-type scales measuring academic stress and academic self-concept. Data were analyzed using t-tests and ANOVA to explore associations between perceptions and demographic variables. Results: Most students reported low levels of academic stress and maintained a positive academic self-concept. Perceived …


Challenges Of Electronic Medical Record Implementation From The Perspective Of Hospital Leaders In Riyadh, Kingdom Of Saudi Arabia's Public Hospitals: A Mixed-Methods Study, Atheer A. Alghamdi, Samiha H. Sayed Mar 2026

Challenges Of Electronic Medical Record Implementation From The Perspective Of Hospital Leaders In Riyadh, Kingdom Of Saudi Arabia's Public Hospitals: A Mixed-Methods Study, Atheer A. Alghamdi, Samiha H. Sayed

Saudi Medical Journal

Objectives: To assesses the challenges of implementing electronic medical records (EMR) from the leaders' perspective in public hospitals in Riyadh, Kingdom of Saudi Arabia (KSA), and explores their suggestions for improvement. Methods: A concurrent mixed research approach using a purposive sample of all hospital leaders (61) involved in EMR in 5 randomly selected public hospitals utilizing EMR in Riyadh. The researchers deployed a semi-structured interview schedule to collect the data. They used descriptive statistics and ordinal regression analysis for quantitative data, and thematic analysis for qualitative data. Results: Indicate that 80.3% of the hospital leaders had a good perception of …


Investigating The Use Of Antidepressants In Treating Major Depressive Disorder: Insights From A Retrospective Study In Saudi Arabia, Hassan A Alsaad, Wajd A Alfaraj, Maryam M Alrababi, Ali M Sonbaa, Dalal M Albakr, Ali Saleh Abensaad, Fadhel A Alomar Mar 2026

Investigating The Use Of Antidepressants In Treating Major Depressive Disorder: Insights From A Retrospective Study In Saudi Arabia, Hassan A Alsaad, Wajd A Alfaraj, Maryam M Alrababi, Ali M Sonbaa, Dalal M Albakr, Ali Saleh Abensaad, Fadhel A Alomar

Saudi Medical Journal

Objectives: To investigate patterns of antidepressant prescribing and continuation rates among patients with major depressive disorder (MDD) in Saudi Arabia and to identify factors associated with treatment persistence. Method: A retrospective study was conducted at King Fahad Hospital of the University between May 2023 and February 2025. Data on patients' demographic characteristics, diagnostic information, and prescribed medications were collected. Initial antidepressant therapy and treatment continuation were evaluated, and potential influencing factors were analyzed. Results: Selective serotonin reuptake inhibitors (SSRIs) accounted for most first-line prescriptions (71%), followed by SSRI/atypical combinations (11%) and serotonin–norepinephrine reuptake inhibitors (SNRIs) (5%). Of the 220 patients …


Growing Evidence For Distinct Clinical Features And Early Diagnostic Age Of Cutaneous T-Cell Lymphoma In Saudi Arabia: A Retrospective Study In A Tertiary Care Center, Abdulhadi Jfri, Renad Fayez Alharthy, Mariya Yahya Ashqan, Hassan Omar Bogari, Al-Anoud Yousef Alkhashan Mar 2026

Growing Evidence For Distinct Clinical Features And Early Diagnostic Age Of Cutaneous T-Cell Lymphoma In Saudi Arabia: A Retrospective Study In A Tertiary Care Center, Abdulhadi Jfri, Renad Fayez Alharthy, Mariya Yahya Ashqan, Hassan Omar Bogari, Al-Anoud Yousef Alkhashan

Saudi Medical Journal

Objectives: To examine trends in Cutaneous T-cell Lymphoma (CTCL) disease presentation in the Western Region of the Kingdom of Saudi Arabia (KSA). Cutaneous T-cell lymphomas (CTCLs) have heterogeneous clinical presentation, and disease characteristics can vary between regions and ethnic groups. Methods: We conducted a local observational study at the Princess Noorah Oncology Center and King Abdulaziz Medical City, Jeddah, with CTCL patients referred to and treated in the Saudi Arabian National Guard facilities from January 2017 to December 2023. Medical records of included patients were retrospectively reviewed. Main outcome measures were demographics and clinical characteristics. Results: The cohort comprised 69 …


Incidence And Risk Factors For Post-Thyroidectomy Hypocalcemia: A National Study From Saudi Arabia, Saad M. Alqahtani, Bader E. Alsharari, Abdulaziz H. Al-Shahrani, Shehata F. Shehata, Moneer E. Almadani, Yousef S. Alalawi Mar 2026

Incidence And Risk Factors For Post-Thyroidectomy Hypocalcemia: A National Study From Saudi Arabia, Saad M. Alqahtani, Bader E. Alsharari, Abdulaziz H. Al-Shahrani, Shehata F. Shehata, Moneer E. Almadani, Yousef S. Alalawi

Saudi Medical Journal

Objectives: Post-thyroidectomy hypocalcemia is the leading cause of post-thyroidectomy hospitalization, adversely affecting patient quality of life. The current study sought to determine the incidence of post-thyroidectomy hypocalcemia, identify risk factors and their clinical significance, and provide an overview of the incidence in different Saudi Arabian cities. Methods: This retrospective analysis included all patients who underwent thyroidectomies at King Salman Armed Forces Hospital Northwestern Region, Tabuk, Saudi Arabia between 2015 and 2021 and had available pre- and post-operative calcium levels and clinical, surgical, and pathological data. Various risk factors were evaluated using binary logistic regression to determine their impact on the …


Evaluation Of Neutrophil-To-Lymphocyte Ratio And Platelet-To-Lymphocyte Ratio As Biomarkers In Missed Abortions, Ayse Yigit Sonmez, Defne Ay Tuncel Mar 2026

Evaluation Of Neutrophil-To-Lymphocyte Ratio And Platelet-To-Lymphocyte Ratio As Biomarkers In Missed Abortions, Ayse Yigit Sonmez, Defne Ay Tuncel

Saudi Medical Journal

Objectives: To evaluate the usability and clinical significance. Missed abortion, a common complication in early pregnancy. Diagnosis typically relies on ultrasonographic findings and clinical criteria. The neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio have attracted considerable interest. Methods: A total of 120 women participated, with 60 diagnosed with missed abortion and 60 with healthy intrauterine pregnancy. This is a retrospective case-control study. Information for the study was gathered from patient file records. Mann-Whitney U Test was used. Logistic regression analysis assessed the magnitude and direction of the relationships between the variables. Results: The youngest participant was 23, while the oldest was 42. …


An Examination Of The Effect On Health Protective Behaviour Of Diabetes And Obesity Awareness And Personal Characteristics In Adults: Structural Equation Modeling, Ayşe Soylu, Pinar Şahin Mar 2026

An Examination Of The Effect On Health Protective Behaviour Of Diabetes And Obesity Awareness And Personal Characteristics In Adults: Structural Equation Modeling, Ayşe Soylu, Pinar Şahin

Saudi Medical Journal

Objectives: The World Health Organization has reported that obesity-related diabetes cases are increasing rapidly. The aim of this study was to examine the effect on health protective behaviour of diabetes and obesity awareness and personal characteristics in adults. Method: This descriptive, cross-sectional, correlational study was conducted with 1241 participants. Data were collected using a Personal Information Form, the Diabetes and Obesity Awareness Scale and Health Protective Behaviour Scale. Data analysis was performed with IBM SPSS vn.23 and IBM AMOS vn.24 software. STROBE was used in reporting. Results: Of the total participants, 45.4% had no diabete and obesity awareness and in …


Clinical Significance Of Ikbkb Mutations: A Focus On Ikbkb-Related Immunodeficiency, Alhomidi Almotiri Mar 2026

Clinical Significance Of Ikbkb Mutations: A Focus On Ikbkb-Related Immunodeficiency, Alhomidi Almotiri

Saudi Medical Journal

Inhibitory kappa B kinase beta (IKBKB, IKK2, or IKKβ ) acts as an activator of the nuclear factor (NF)-κ B signaling cascade that is involved in regulating normal physiological processes and is dysregulated in several pathological processes including immunological disorders. Mutations in IKBKB have been found to cause immune deficiency syndromes. Inherited loss-of-function mutations in IKBKB lead to severe or lethal immune deficiency. In this review, the clinical significance of IKBKB mutations will be reviewed in the context of immune deficiency syndromes. All published clinical cases of IKBKB mutations relevant to immune deficiency, either caused by loss- or gain-of-function mutations …


Brief Geriatric Assessment (Bga): An Evidence-Based Tool For Improving Care Of Older Adults, Assim M. Alabdulkader Mar 2026

Brief Geriatric Assessment (Bga): An Evidence-Based Tool For Improving Care Of Older Adults, Assim M. Alabdulkader

Saudi Medical Journal

The Brief Geriatric Assessment is an approach for rapidly identifying high-risk older adults and guiding timely interventions in busy clinical settings. Unlike the Comprehensive Geriatric Assessment, albeit the gold standard, which is resource-intensive, the Brief Geriatric Assessment offers a scalable alternative by using validated, time-efficient tools to screen for common geriatric syndromes. This narrative state-of-the-art review synthesizes the evidence and best practices regarding the concept, structure, and clinical application of the Brief Geriatric Assessment. It compares the Brief Geriatric Assessment and Comprehensive Geriatric Assessment from theoretical and practical perspectives and outlines how the former can be integrated into healthcare settings, …


Sleep Disorder Phenotypes And The Risk Of Incident Heart Failure: A Meta-Analysis With Mendelian Randomization Validation, Fang Yan, Lihua Fan, Yunhu Chen Mar 2026

Sleep Disorder Phenotypes And The Risk Of Incident Heart Failure: A Meta-Analysis With Mendelian Randomization Validation, Fang Yan, Lihua Fan, Yunhu Chen

Saudi Medical Journal

Objectives: To quantify how specific sleep-disorder phenotypes are related to incident heart failure (HF) using a meta-analysis of cohort data and to probe causal relevance via 2-sample Mendelian randomization (MR). Methods: Fourteen cohorts comprised of participants without HF at baseline were pooled (49,501 exposed; 337,317 controls). A random effects meta-analysis produced pooled hazard ratios (HRs) with 95% confidence intervals (CIs). A bidirectional two-sample MR was used to evaluate the causal effects of sleep phenotypes on HF. Results: Overall, sleep disorders were linked to a higher incidence of HF (pooled HR 1.46; 95% CI 1.30–1.63; pp < 0.001), whereas insomnia was not independently associated with HF (pooled HR 1.11; 95% CI 0.75–1.62; p = 0.609). The …


National Heart Center Perfusion Guidelines, Fareed A. Khouqeer, Abdulaziz S. Albaradei, Ahmed A. Jamjoom, Husain H. Jabbad, Khalid A. Iskander, Omar M. Zainalabdeen, Yasser A. Alheraish, Ebtesam M. Alanazi, Abdulrahman F. Alhumiany, Areej S. Al Buraiki, Muhammad W. Rana, Muhamad I. Jelaldin, Zainab A. Zainaldeen, Bander A. Zamzami, Budoor S. Al Aujan, Ahmed M. Galal Elsherbeny Feb 2026

National Heart Center Perfusion Guidelines, Fareed A. Khouqeer, Abdulaziz S. Albaradei, Ahmed A. Jamjoom, Husain H. Jabbad, Khalid A. Iskander, Omar M. Zainalabdeen, Yasser A. Alheraish, Ebtesam M. Alanazi, Abdulrahman F. Alhumiany, Areej S. Al Buraiki, Muhammad W. Rana, Muhamad I. Jelaldin, Zainab A. Zainaldeen, Bander A. Zamzami, Budoor S. Al Aujan, Ahmed M. Galal Elsherbeny

Saudi Medical Journal

Objectives: To establish the[-28pc]AU: Add abbreviated academic degree for authors Fareed A. Khouqeer and Yasser A. Alheraish. first national standards and guidelines for best practice in perfusion for patients undergoing cardiothoracic surgery in Saudi Arabia. Cardiopulmonary bypass (CPB) enables complex cardiac surgeries; however, it poses risks of potential complications.

Methods: We used the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach to develop these guidelines and assess the certainty of evidence through a collaborative process. A panel of 16 Cardiovascu- lar perfusion experts across Saudi Arabia formulated 22 key clinical questions relevant to local practice. PubMed, Scopus, and Embase …


White Islands In A Sea Of Red, Dana S. Alessa, Faisal A. Alghubaywi, Sultan Al-Khenaizan Feb 2026

White Islands In A Sea Of Red, Dana S. Alessa, Faisal A. Alghubaywi, Sultan Al-Khenaizan

Saudi Medical Journal

No abstract provided.


Risk Factors And Outcomes Of Acute Kidney Injury In Children With Congenital Heart Disease Following Cardiac Surgery, Zaher F. Zaher, Mohammad A. Shalaby, Khalid A. Alhasan, Mohammed A. Ghazi, Ghassan A. Mustafa, Yasser S. Bamashmous, Muath A. Hadram, Ibrahim A Sandokji, Abrar N. Alsharief, Abdulaziz M Bahassan, Amr S. Albanna, Osama Y. Safder, Jameela A. Kari Feb 2026

Risk Factors And Outcomes Of Acute Kidney Injury In Children With Congenital Heart Disease Following Cardiac Surgery, Zaher F. Zaher, Mohammad A. Shalaby, Khalid A. Alhasan, Mohammed A. Ghazi, Ghassan A. Mustafa, Yasser S. Bamashmous, Muath A. Hadram, Ibrahim A Sandokji, Abrar N. Alsharief, Abdulaziz M Bahassan, Amr S. Albanna, Osama Y. Safder, Jameela A. Kari

Saudi Medical Journal

Objectives: To investigate the incidence and risk factors for Acute kidney injury (AKI) following cardiac surgery in children with congenital heart diseases, and to identify modifiable factors that remain insufficiently studied. Acute kidney injury is common after cardiac surgery for children with congenital heart disease (CHD). Children with AKI are known to have complicated hospital courses, including their need for kidney replacement therapy, and have increased mortality.

Methods: We conducted a retrospective analysis of children admitted to the pediatric cardiac intensive care unit (PCICU) at King Abdulaziz University Hospital over 7 years (2014–2021), using the Kidney Disease Improving Global Outcome …


Bridging Diagnosis And Prevention: The Impact Of Ccta On Cad Risk Management - A Retrospective Single-Center Study, Adil I. Jumani, Ghada A. Rashwan, Hadiza O. Ibrahim, Jumaa S. Aldhaheri, Safaa M. Almohdar, Hassan Hassan, Khaled M. Alfakih Feb 2026

Bridging Diagnosis And Prevention: The Impact Of Ccta On Cad Risk Management - A Retrospective Single-Center Study, Adil I. Jumani, Ghada A. Rashwan, Hadiza O. Ibrahim, Jumaa S. Aldhaheri, Safaa M. Almohdar, Hassan Hassan, Khaled M. Alfakih

Saudi Medical Journal

Objective: To assess the clinical utility of coronary computed tomographic angiography (CCTA) for diagnosing coronary artery disease (CAD) in patients with stable chest pain at Zayed Military Hospital, focusing on its impact on management and preventive strategies.

Background: Chest pain is a common presenting symptom in hospitals. Coronary computed tomographic angiography offers an accurate, non-invasive method for diagnosing CAD in patients with low to intermediate pre-test probability.

Methods: A retrospective review of all 417 patients who underwent CCTA from January to December 2024 was conducted. Demographics, calcium scores, CAD findings, comorbidities, and subsequent management, including invasive coronary angiography and pharmacological …


A Bibliometric Analysis Of The Most Influential And Impactful Plastic Surgery Publications From Saudi Arabia, Hatan Mortada, Abdulaziz Alnufaei, Amal Tuaki Aljuaid, Zainab Ahmed Al Hubail, Waad Nawaf Alanazi, Abdulaziz Suleiman Jasaniah, Sarah Abdullah Ramzi, Amr Youssef Arkoubi Feb 2026

A Bibliometric Analysis Of The Most Influential And Impactful Plastic Surgery Publications From Saudi Arabia, Hatan Mortada, Abdulaziz Alnufaei, Amal Tuaki Aljuaid, Zainab Ahmed Al Hubail, Waad Nawaf Alanazi, Abdulaziz Suleiman Jasaniah, Sarah Abdullah Ramzi, Amr Youssef Arkoubi

Saudi Medical Journal

Objective: To analyze the most cited plastic surgery articles from Saudi Arabia, focusing on publication trends, leading contributors, collaboration patterns, and thematic areas.

Methods: We conducted a bibliometric analysis using the Web of Science Core Collection (1990–2025). Keywords covering plastic surgery subfields were combined with geographic identifiers (“Saudi Arabia,” “KSA,” “Kingdom of Saudi Arabia”) using Boolean operators. Only English-language original and review articles were included. Citation metrics, authorship networks, and keyword co-occurrence were analyzed with VOSviewer and the bibliometrix R package.

Results: We identified 1,013 Saudi-affiliated plastic surgery publications, receiving 7,929 citations. The top 100 most-cited articles averaged 39.3 citations …


Evaluating Diagnostic Capability Of Computed Tomography And Role Of Bronchoscopy In Admitted Cases With Pulmonary Diseases, Khawaja B. Waheed, Zubair Ahmed, Asif Mahmood, Jumana H. Masoudi, Ahmed O. Z. Alanazi, Aldana M. Almubireek, Zoha Bilal, Rood A. Alshehri, Mays H. Mahasneh, Zechariah Jebakumar Arulanantham Feb 2026

Evaluating Diagnostic Capability Of Computed Tomography And Role Of Bronchoscopy In Admitted Cases With Pulmonary Diseases, Khawaja B. Waheed, Zubair Ahmed, Asif Mahmood, Jumana H. Masoudi, Ahmed O. Z. Alanazi, Aldana M. Almubireek, Zoha Bilal, Rood A. Alshehri, Mays H. Mahasneh, Zechariah Jebakumar Arulanantham

Saudi Medical Journal

Objective: To evaluate capability of CT scan in diagnosing pulmonary diseases, identifying malignancy, and role of bronchoscopy in confirming or changing imaging diagnosis.

Method: A retrospective record-based cross-sectional study was performed evaluating data of all consecutive adult patients who had CT and bronchoscopies performed in a period of 2 years (between Jan. 2023 to Jan. 2025). Demographic, clinical symptoms, CT chest and bronchoscopy findings were recorded. Final diagnoses were based on clinical (improvement with time or resolution of symptoms with specific antimicrobial drugs), laboratory (bronchoalveolar lavage and biopsy, blood or sputum cultures) and imaging guided biopsies (where performed). Patients without …


A Retrospective Review Of Antimicrobial Usage And Indications At End-Of-Life For Oncology Patients In A Tertiary Cancer Center In Saudi Arabia, Nabil A. Almouaalamy, Lama A. Banjar, Hattan A. Hassani, Ahmed A. Alqerafi, Abdulrahman I. Ezzi, Bader K. Alaslab, Abdulaziz K. Allhybi, Abdulaziz N. Aljohani, Nora N. Almouaalamy, Hassan A. Almarhabi Feb 2026

A Retrospective Review Of Antimicrobial Usage And Indications At End-Of-Life For Oncology Patients In A Tertiary Cancer Center In Saudi Arabia, Nabil A. Almouaalamy, Lama A. Banjar, Hattan A. Hassani, Ahmed A. Alqerafi, Abdulrahman I. Ezzi, Bader K. Alaslab, Abdulaziz K. Allhybi, Abdulaziz N. Aljohani, Nora N. Almouaalamy, Hassan A. Almarhabi

Saudi Medical Journal

Objectives: To investigate antimicrobial usage patterns, indications, and outcomes in end-of-life (EOL) oncology patients at Princess Noorah Oncology Center (PNOC), King Abdulaziz Medical City, Jeddah, Saudi Arabia. The use of antimicrobials in oncology patients in EOL care has raised concerns about their appropriateness and the increasing issue of antimicrobial resistance.

Methods: The study is a retrospective chart review of cancer patients treated at the PNOC from January 1, 2017, to January 31, 2022. The inclusion criteria included cancer patients ≥18 years who died during their admission. The exclusion criteria included subjects who did not meet the inclusion criteria.

Results: Among …


Risk Factors, Clinical Manifestations, And Treatment Outcomes Of Primary Bone Sarcomas, Ali H. Alyami, Mohammed A. Alkhotani, Abdulaziz A. Alsiraihi, Mohammed M. Bukhari, Abdulrahman S. Alqurashi, Abdulrahman M. Alghamdi, Anas R. Kurdi, Bader A. Khawaji Feb 2026

Risk Factors, Clinical Manifestations, And Treatment Outcomes Of Primary Bone Sarcomas, Ali H. Alyami, Mohammed A. Alkhotani, Abdulaziz A. Alsiraihi, Mohammed M. Bukhari, Abdulrahman S. Alqurashi, Abdulrahman M. Alghamdi, Anas R. Kurdi, Bader A. Khawaji

Saudi Medical Journal

Objective: To investigate the risk factors, clinical manifestations, and treatment outcomes in patients with Primary Bone Sarcomas (PBS).

Methods: This retrospective study included all patients with PBS treated between June 2016 and December 2023 at King Abdulaziz Medical City, excluding patients with incomplete data, presence of other malignancies, diagnosis at autopsy, or unknown metastasis. Data were analyzed using SPSS software version 27. A p-value of less than 0.05 was considered statistically significant. Log Rank test was used for survival analysis

Results: The study included 127 patients. Common past medical history included diabetes (7%), hypertension (5.5%), and metastasis at presentation (15%). …


The Effect Of Motivational Interviewing On Glycemic Control Among Saudi Persons With Type 2 Diabetes: A Feasibility Study, Fatima Y. Al-Slail, Ibtihal M. Bin Jumah, Kawther O. Abdelfadil, Sahar M. Fadl, Amaal O. Almutairy, Abdullah F. Alanazi, Omer O. Kheir Feb 2026

The Effect Of Motivational Interviewing On Glycemic Control Among Saudi Persons With Type 2 Diabetes: A Feasibility Study, Fatima Y. Al-Slail, Ibtihal M. Bin Jumah, Kawther O. Abdelfadil, Sahar M. Fadl, Amaal O. Almutairy, Abdullah F. Alanazi, Omer O. Kheir

Saudi Medical Journal

Objectives: To assess the feasibility of integrating a motivational interviewing approach with a comprehensive diabetes care program in Saudi primary care clinics. Approximately 23.1% of the adult Saudi population is diabetic, yet only 22.5% of these diabetic individuals maintain adequate glycemic control as defined by Hemoglobin A1c (HbA1c) levels <7%.

Methods: This quasi-experimental study employed pre- and post-evaluation methods to compare HbA1c levels among persons with uncontrolled diabetes before and after implementing a motivational interviewing (MI) and comprehensive care program. Adults with type 2 DM were included. The MI approach was used to educate and motivate the patients. Starting from November …


Healthcare Practitioners’ Satisfaction With Ministry Of Health Electronic Programs In Primary Healthcare Centers In Abha: A Comprehensive Analysis, Bander A. Alasmari, Majed M. Alsaleh, Abdullah Saeed, Mohammed Y. Aseri, Meteb A. Albraik, Nawal M. Assiri, Khaled A. Alasiri, Maryam A. Alrashadi, Mohammed Y. Alqasem, Faisal A. Faya, Mozoun D. Alahmari Feb 2026

Healthcare Practitioners’ Satisfaction With Ministry Of Health Electronic Programs In Primary Healthcare Centers In Abha: A Comprehensive Analysis, Bander A. Alasmari, Majed M. Alsaleh, Abdullah Saeed, Mohammed Y. Aseri, Meteb A. Albraik, Nawal M. Assiri, Khaled A. Alasiri, Maryam A. Alrashadi, Mohammed Y. Alqasem, Faisal A. Faya, Mozoun D. Alahmari

Saudi Medical Journal

Objective: This study assessed the satisfaction of health care providers with MOH electronic programs in Abha primary care centers and identified key drivers of user satisfaction.

Methods: Cross sectional survey of 152 physicians 48.7, nurses 27.0, allied health staff 21.1 and lab technicians 3.3 from May to July 2025. Participants had to be using MOH electronic systems daily. Descriptive stats and Spearman correlations examine links between satisfaction and system features.

Results: Among 152 respondents 98.7 used at least one MOH program daily.Raqim was most used 89.5. Overall, 11.2 were very satisfied, 44.1 satisfied, 28.3 neutral, and 16.4 dissatisfied. Significant drivers …


Bridging The Evidence Gap: A Retrospective Lens On Survival And Treatment Patterns In Older Patients With Colorectal Cancer, Emad M. Tashkandi Feb 2026

Bridging The Evidence Gap: A Retrospective Lens On Survival And Treatment Patterns In Older Patients With Colorectal Cancer, Emad M. Tashkandi

Saudi Medical Journal

Objectives: To advise evidence-based strategies and healthcare policies to optimize the management of older adults with colorectal cancer (CRC) in the region. Older adults are disproportionately affected by CRC but are underrepresented in clinical trials. Hence, real-world data are crucial in guiding treatment in this population.

Methods: We conducted a retrospective cohort study involving patients aged ≥65 years diagnosed with CRC between 2015 and 2021 at King Abdullah Medical City, Makkah, Saudi Arabia. Clinical data, treatment patterns, and survival outcomes were analyzed.

Results: Among 256 patients (mean age 74.7; 61.7% male), 75% had an Eastern Cooperative Oncology Group performance status …


Anatomical Distribution And Extent Of Carotid Plaque In Early Inflammatory Polyarthritis, Fahad F. Almutairi Feb 2026

Anatomical Distribution And Extent Of Carotid Plaque In Early Inflammatory Polyarthritis, Fahad F. Almutairi

Saudi Medical Journal

Objective: To compare the extent and anatomical distribution of carotid atherosclerotic plaques in the carotid artery segments between patients with early Inflammatory Polyarthritis (IP) and age- and sex-matched controls, and to assess associated cardiovascular and disease-specific risk factors.

Methods: This retrospective study was conducted at King Abdulaziz University Hospital (June 2022 to April 2023), 349 patients (70% female; age 50.74 years; 41.81-58.34) and 115 matched controls (66% female; age 52.28 years; 42.29-58.42) underwent carotid ultrasound examination. Associations between plaques and cardiovascular were assessed.

Results: Plaques were significantly more common among patients than controls (46.1% vs. 27.8%, p = 0.0006), particularly …


Biomarkers Of Multiorgan Failure In Covid-19: A Predictive Framework For Disease Severity And Clinical Outcomes, Wesam A. Nasif, Mohammed H. Mukhtar, Mohammad Althubiti, Abeer Shaker El Moursy Ali Feb 2026

Biomarkers Of Multiorgan Failure In Covid-19: A Predictive Framework For Disease Severity And Clinical Outcomes, Wesam A. Nasif, Mohammed H. Mukhtar, Mohammad Althubiti, Abeer Shaker El Moursy Ali

Saudi Medical Journal

Objective: To investigate the predictive value of inflammatory, liver, renal, and cardiac biomarkers in relation to the progression of multiorgan failure (MOF) in COVID-19 patients. A primary goal was to identify which of these markers served as the most discriminative predictors of disease severity.

Methods: A retrospective cohort study was carried out between December 2020 and February 2023 to collect data from 1,803 COVID-19 patients from data records in different hospitals in Makkah, Saudi Arabia. The ROC curve analysis evaluated the diagnostic and predictive performance of selected biomarkers.

Results: Inflammatory markers such as CRP and D-dimer were evaluated, but ferritin …


Role Of Artificial Intelligence In Infectious Diseases And Antimicrobial Resistance: A Comprehensive Review On Diagnostic, Treatment, And Prevention Aspects, Naveed Ahmed, Mansoor Alghamdi Feb 2026

Role Of Artificial Intelligence In Infectious Diseases And Antimicrobial Resistance: A Comprehensive Review On Diagnostic, Treatment, And Prevention Aspects, Naveed Ahmed, Mansoor Alghamdi

Saudi Medical Journal

Artificial intelligence (AI) plays a significant role in managing infectious diseases by enhancing diagnosis, treatment, and preventive measures. AI-assisted tools have predictive analysis ability for incoming outbreaks, including the emergence of antimicrobial resistance (AMR). AI-assisted tools facilitate the treatment methods by tailoring personalized medicine according to the specific disease history of the patient, immune response, and genetics. Advanced vaccine development by various AI-assisted in silico tools is becoming easy, leading to faster vaccine discovery and more efficient vaccine design with a more immunogenic response. Despite huge benefits, a few limitations are also encountered, including biases in algorithms, data privacy, and …


Artificial Intelligence In Radiology: Hidden Fragilities And The Path To Resilience, Mustafa S. Alhasan Feb 2026

Artificial Intelligence In Radiology: Hidden Fragilities And The Path To Resilience, Mustafa S. Alhasan

Saudi Medical Journal

Radiology artificial intelligence (AI) is advancing however its adoption faces fragile foundations that threaten sustainability. Despite bold promises of efficiency and accuracy, current deployment is undermined by weaknesses in economics, evidence, infrastructure, human factors, regulation, security, and environmental impact. Nearly 90% of radiology AI studies report process metrics rather than patient outcomes, while hidden costs elevate ownership to 400% to 500% of subscription fees. Technical fragilities include 25% or greater performance loss with routine protocol or scanner shifts, compounded by vendor consolidation that has eliminated 63% of companies since 2020, creating migration costs averaging 180,000 dollars per exit. Human factor …


Childhood Obesity: Global Burden, Multifactorial Etiologies, Biological Mechanisms, And Emerging Interventions For Prevention And Management, Fahad H. Baali Feb 2026

Childhood Obesity: Global Burden, Multifactorial Etiologies, Biological Mechanisms, And Emerging Interventions For Prevention And Management, Fahad H. Baali

Saudi Medical Journal

Childhood obesity, characterized by excessive accumulation of body fat that adversely affects health, is a global public health challenge. It affects approximately 8.2% of children and adolescents globally and contributes significantly to the burden of chronic diseases in later life. Obese children are at increased risk of developing metabolic disorder cluster, type 2 diabetes (T2D), coronary artery disease (CAD), and psychosocial complications. Increasing prevalence of childhood obesity imposes substantial economic costs and highlights the urgent need for effective prevention and management strategies. The causes of childhood obesity are multifactorial including genetic predispositions, environmental influences, dietary habits, and physical inactivity. Early …


Bleeding Avoidance Strategies In Patients With Atrial Fibrillation, Antonio Landi, Marco Valgimigli Feb 2026

Bleeding Avoidance Strategies In Patients With Atrial Fibrillation, Antonio Landi, Marco Valgimigli

Saudi Medical Journal

No abstract provided.


Obesity As A Health Priority: Insights From Research Productivity In The Arab World, Rania Hammami, Mirvat Alsnag Feb 2026

Obesity As A Health Priority: Insights From Research Productivity In The Arab World, Rania Hammami, Mirvat Alsnag

Saudi Medical Journal

No abstract provided.


National Heart Center/Saudi Heart Association 2025 Guidelines For Cardiovascular Diseases Prevention And Risk Assessment, Jamilah S Alrahimi, Shukri M. Al Saif, Laith Hussain-Alkhateeb, Ali M. Albarrati, Owayed M. Alshammeri, Talal S. Alghamdi, Khalid A. Al Faraidy, Ada M Al-Qunaibet, Nada A. Alnaji, Rasha A. Alfawaz, Waleed M. Alharbi, Waleed A. Alhabeeb, Fahad M. Alnouri, Adel A. Tash Feb 2026

National Heart Center/Saudi Heart Association 2025 Guidelines For Cardiovascular Diseases Prevention And Risk Assessment, Jamilah S Alrahimi, Shukri M. Al Saif, Laith Hussain-Alkhateeb, Ali M. Albarrati, Owayed M. Alshammeri, Talal S. Alghamdi, Khalid A. Al Faraidy, Ada M Al-Qunaibet, Nada A. Alnaji, Rasha A. Alfawaz, Waleed M. Alharbi, Waleed A. Alhabeeb, Fahad M. Alnouri, Adel A. Tash

Saudi Medical Journal

Objectives: To develop an evidence-based clinical guideline for the prevention and management of cardiovascular diseases (CVDs) in Saudi Arabia, tailored to local epidemiology and healthcare needs.

Methods: A multidisciplinary task force comprising cardiologists, public health specialists, and epidemiologists from different healthcare sectors in Saudi Arabia developed the guideline. Evidence synthesis was based on a comprehensive literature review and adaptation of international guidelines, particularly the 2021 European Society of Cardiology recommendations, contextualized to the Saudi setting.

Results: The guideline provides recommendations for both primary and secondary CVD prevention. Primary prevention emphasizes risk assessment incorporating genetic, lifestyle, and clinical factors, as well …