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Research outputs 2022 to 2026

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Staff Perceptions Of The Effectiveness Of Managerial Communication During The Covid-19 Pandemic: A Cross-Sectional Study, Gemma Doleman, Linda Coventry, Amanda Towell-Barnard, Manonita Ghosh, Lucy Gent, Rosemary Saunders, Beverly O'Connell Jan 2023

Staff Perceptions Of The Effectiveness Of Managerial Communication During The Covid-19 Pandemic: A Cross-Sectional Study, Gemma Doleman, Linda Coventry, Amanda Towell-Barnard, Manonita Ghosh, Lucy Gent, Rosemary Saunders, Beverly O'Connell

Research outputs 2022 to 2026

Aims: This work aims to explore staff perceptions of (1) the effectiveness of organizational communication during the COVID-19 pandemic and (2) the impact of organizational communication on staff well-being and ability to progress their work and patient care. Background: Effective coordination and communication are essential in a pandemic management response. However, the effectiveness of communication strategies used during the COVID-19 pandemic is not well understood. Design: An exploratory cross-sectional research design was used. A 33-item survey tool was created for the study. Methods: The study was conducted at a tertiary teaching hospital in Western Australia. Convenience sampling was used to …


The Relationship Between Responsible Financial Behaviours And Financial Wellbeing: The Case Of Buy-Now-Pay-Later, Robert Powell, Anh Do, Denise Gengatharen, Jaime Yong, Rasiah Gengatharen Jan 2023

The Relationship Between Responsible Financial Behaviours And Financial Wellbeing: The Case Of Buy-Now-Pay-Later, Robert Powell, Anh Do, Denise Gengatharen, Jaime Yong, Rasiah Gengatharen

Research outputs 2022 to 2026

Buy-now-pay-later (BNPL) in Australia is a rapidly growing payment innovation. Regulators and consumer groups have expressed concerns at the financial risks posed by BNPL. As BNPL is not regulated under consumer credit law, financial regulator and consumer groups have recommended that BNPL users adopt a range of responsible financial behaviours for their financial wellbeing. This study, using a survey of BNPL users and structural equation modelling, shows a link between most of these recommended financially responsible behaviours and financial wellbeing and that the financial behaviours of younger users (aged under 25) place them at greater risk of reduced financial wellbeing.


The Role Of Authentic Leadership On Healthcare Street-Level Bureaucrats’ Well-Being During The Pandemic, Nasim Salehi, Yvonne Brunetto, Tom Dick Jan 2023

The Role Of Authentic Leadership On Healthcare Street-Level Bureaucrats’ Well-Being During The Pandemic, Nasim Salehi, Yvonne Brunetto, Tom Dick

Research outputs 2022 to 2026

This study uses Conservation of Resources Theory, to explain Street-Level Bureaucrats’ (SLBs) workplace behavioural responses to threats to their well-being. We examine whether authentic leadership within street-level organisations positively impacts employee well-being by increasing SLBs’ perception of personal resources, and reducing their perceptions of work harassment. The research design comprises a survey that solicited quantitative and qualitative data from 163 healthcare SLBs working in Australian hospitals during the pandemic in April 2020. Analysis of the means indicates low levels of satisfaction with leadership and low levels of well-being for SLBs. The structural equation modelling findings show that poor leadership is …


Theory-Based Behaviour Change Intervention To Promote Mental Health Help-Seeking Among Older Adults In Australia: Initial Dissemination And Acceptability, Claire Adams, Eyal Gringart, Natalie Strobel Jan 2023

Theory-Based Behaviour Change Intervention To Promote Mental Health Help-Seeking Among Older Adults In Australia: Initial Dissemination And Acceptability, Claire Adams, Eyal Gringart, Natalie Strobel

Research outputs 2022 to 2026

Objective: Rates of help-seeking for mental health problems among older adults are low and initiatives to increase help-seeking in older populations are limited. To our knowledge, no interventions have aimed to promote help-seeking among older adults by tapping internal motivations to seek help. In this paper, we describe the development of a theory-based intervention designed to promote mental health help-seeking among older adults in Australia, using an internal motivation paradigm. Methods: The intervention was co-designed through a consultative process with nine key stakeholders who represented five main groups: primary health-care providers, mental health professionals, health-care executives, community organisations and consumers. …


Toddlers May Be Getting Enough Iron In Long Day-Care Services After All, Michaela Johnston, Therese O'Sullivan, Amanda Devine, Ruth Wallace, Leesa Costello, Ros Sambell Jan 2023

Toddlers May Be Getting Enough Iron In Long Day-Care Services After All, Michaela Johnston, Therese O'Sullivan, Amanda Devine, Ruth Wallace, Leesa Costello, Ros Sambell

Research outputs 2022 to 2026

Background: Previous research has suggested that toddlers are not provided with adequate dietary iron in long-day care (LDC) services. However, the iron bioavailability provided is unknown. The present study aimed to investigate the amount and bioavailability of iron provided to toddlers aged 2–3 years at LDC services. Methods: A cross-sectional audit was conducted using a 2-day weighed food record of 30 LDC services. Iron provision (not child intake) in LDC services across Perth, Australia was compared with the estimated average requirements (EAR) and LDC services provision guidelines (50% of EAR = 2 mg/day based on a 14% bioavailability factor). Bioavailability …


Why Do Employees Respond Differently To Corporate Social Responsibility? A Study Of Substantive And Symbolic Corporate Social Responsibility, Mehran Nejati, Azadeh Shafaei Darastani Jan 2023

Why Do Employees Respond Differently To Corporate Social Responsibility? A Study Of Substantive And Symbolic Corporate Social Responsibility, Mehran Nejati, Azadeh Shafaei Darastani

Research outputs 2022 to 2026

Corporate social responsibility (CSR) plays an increasingly significant role in business and can impact organizational performance and sustainability. However, the degree to which stakeholders see the organization as legitimate may depend on the perceived authenticity of CSR processes and practices. As internal stakeholders, employees have a strong influence on organizational outcomes. CSR, in turn, has been found to positively influence several employee outcomes. To examine the mechanisms of this relationship, this study questioned when and how CSR enhances employees' perceptions and results in affective commitment. Drawing on a time-lagged sample of 317 full-time employees in Australia, we found that substantive …


Locally Performed Postoperative Circulating Tumour Dna Testing Performed During Routine Clinical Care To Predict Recurrence Of Colorectal Cancer, Ryan Cohen, Aaron Beasley, Melanie Mccoy, Cameron Platell, Katie Meehan, Elin Gray, Kathy Fuller Jan 2023

Locally Performed Postoperative Circulating Tumour Dna Testing Performed During Routine Clinical Care To Predict Recurrence Of Colorectal Cancer, Ryan Cohen, Aaron Beasley, Melanie Mccoy, Cameron Platell, Katie Meehan, Elin Gray, Kathy Fuller

Research outputs 2022 to 2026

Background: Identifying patients at high risk for colorectal cancer recurrence is essential for improving prognosis. In the postoperative period, circulating tumour DNA (ctDNA) has been demonstrated as a significant prognostic indicator of recurrence. These results have been obtained under the strict rigours of clinical trials, but not validated in a real-world setting using in-house testing. We report the outcomes of locally performed postoperative ctDNA testing conducted during routine clinical care and the association with the recurrence of colorectal cancer. Methods: We recruited 36 consecutive patients with newly diagnosed colorectal cancer between 2018 and 2020. Postoperative plasma samples were collected at …


Closing The Shell: Gas-Phase Solvation Of Halides By 1,3-Butadiene, Peter D. Watson, Christian T. Haakansson, Hayden T. Robinson, Timothy R. Corkish, James Brookes, Allan J. Mckinley, Duncan A. Wild Jan 2023

Closing The Shell: Gas-Phase Solvation Of Halides By 1,3-Butadiene, Peter D. Watson, Christian T. Haakansson, Hayden T. Robinson, Timothy R. Corkish, James Brookes, Allan J. Mckinley, Duncan A. Wild

Research outputs 2022 to 2026

Gas-phase solvation of halides by 1,3-butadiene has been studied via a combination of photoelectron spectroscopy and density functional theory. Photoelectron spectra for X−⋯(C4H6)n (X=Cl, Br, I where n=1-3, 1–3 and 1–7 respectively) are presented. For all complexes, the calculated structures indicate that butadiene is bound in a bidentate fashion through hydrogen-bonding, with the chloride complex showing the greatest degree of stabilisation of the internal C−C rotation of cis-butadiene. In both Cl− and Br− complexes, the first solvation shell is shown to be at least n = 4 from the vertical detachment energies (VDEs), however for I−, increases in the …


Confined Tri-Functional Feox@Mno2@Sio2 Flask Micromotors For Long-Lasting Motion And Catalytic Reactions, Yangyang Yang, Lei Shi, Jingkai Lin, Panpan Zhang, Kunsheng Hu, Shuang Meng, Peng Zhou, Xiaoguang Duan, Hongqi Sun, Shaobin Wang Jan 2023

Confined Tri-Functional Feox@Mno2@Sio2 Flask Micromotors For Long-Lasting Motion And Catalytic Reactions, Yangyang Yang, Lei Shi, Jingkai Lin, Panpan Zhang, Kunsheng Hu, Shuang Meng, Peng Zhou, Xiaoguang Duan, Hongqi Sun, Shaobin Wang

Research outputs 2022 to 2026

H2O2-fueled micromotors are state-of-the-art mobile microreactors in environmental remediation. In this work, a magnetic FeOx@MnO2@SiO2 micromotor with multi-functions is designed and demonstrated its catalytic performance in H2O2/peroxymonosulfate (PMS) activation for simultaneously sustained motion and organic degradation. Moreover, this work reveals the correlations between catalytic efficiency and motion behavior/mechanism. The inner magnetic FeOx nanoellipsoids primarily trigger radical species (OH and O2−) to attack organics via Fenton-like reactions. The coated MnO2 layers on FeOx surface are responsible for decomposing H2O2 into O2 …


Natural Manganese Ores For Efficient Removal Of Organic Pollutants Via Catalytic Peroxymonosulfate-Based Advanced Oxidation Processes, Zhengxin Yao, Roufei Chen, Ning Han, Hongqi Sun, Ngie Hing Wong, Lusi Ernawati, Shaobin Wang, Jaka Sunarso, Shaomin Liu Jan 2023

Natural Manganese Ores For Efficient Removal Of Organic Pollutants Via Catalytic Peroxymonosulfate-Based Advanced Oxidation Processes, Zhengxin Yao, Roufei Chen, Ning Han, Hongqi Sun, Ngie Hing Wong, Lusi Ernawati, Shaobin Wang, Jaka Sunarso, Shaomin Liu

Research outputs 2022 to 2026

Peroxymonosulfate-based advanced oxidation processes (PMS-AOPs) for in situ persistent organic pollutant (POP) remediation in aqueous solutions can be a promising technology. However, this technology is constrained by its high toxicity and cost of metal oxide and non-metal catalysts for PMS activation. Here, we investigated the catalytic performance of a widely available natural mineral, manganese ore (MO), for PMS activation. A series of natural MO samples in an aqueous solution were prepared via the Fenton-like reaction. The samples' crystalline structure, surface morphology, textural properties, and other surface characteristics of the selected MO were systematically characterized. The effects of PMS concentration and …


Teenagers Learn Through Play Too: Communicating High Expectations Through A Playful Learning Approach, Olivia Johnston, Helen Wildy, Jennifer Shand Jan 2023

Teenagers Learn Through Play Too: Communicating High Expectations Through A Playful Learning Approach, Olivia Johnston, Helen Wildy, Jennifer Shand

Research outputs 2022 to 2026

Play-based learning is an approach used in early childhood education that is well supported by research on its varieties and effectiveness for young children’s learning. Play-based learning meets the developmental needs of young children, but new research presented in this paper suggests that teenagers learn through play too. The experience of 25 Year 10 students in three Western Australian government schools was drawn upon to generate grounded theory about how students experience their teachers’ expectations of them, which included findings that playful learning approaches communicated high teacher expectations. The students were shadow-studied in their classrooms and interviewed at the end …


Determinants Of Intention To Use E-Wallet: Personal Innovativeness And Propensity To Trust As Moderators, Madugoda Gunaratnege Senali, Mohammad Iranmanesh, Fatin Nadzirah Ismail, Noor Fareen Abdul Rahim, Mana Khoshkam, Maryam Mirzaei Jan 2023

Determinants Of Intention To Use E-Wallet: Personal Innovativeness And Propensity To Trust As Moderators, Madugoda Gunaratnege Senali, Mohammad Iranmanesh, Fatin Nadzirah Ismail, Noor Fareen Abdul Rahim, Mana Khoshkam, Maryam Mirzaei

Research outputs 2022 to 2026

This study aims to investigate the determinants of intention to use e-wallets. Drawing on the technology acceptance model (TAM), the conceptual framework was developed. The study extends the TAM in the context of e-wallets, by testing the influences of product-related factors namely perceived compatibility, perceived risk, and perceived emotions and investigating the moderating impacts of personal innovativeness and propensity to trust. To conduct an empirical study, the data were collected from Malaysian individuals with no experience with e-wallets using an online survey. Data from 374 participants were obtained and analyzed using the partial least squares technique. The results showed that …


Integrated Clinical Pathways For Lower Limb Orthopaedic Surgeries: An Updated Systematic Review, Huaqiong Zhou, Irene M. Ngune, Pam Roberts, Phillip Della Jan 2023

Integrated Clinical Pathways For Lower Limb Orthopaedic Surgeries: An Updated Systematic Review, Huaqiong Zhou, Irene M. Ngune, Pam Roberts, Phillip Della

Research outputs 2022 to 2026

Objective

The objective of the study was to comprehensively synthesise the components of integrated clinical pathways (ICPs) and post-operative outcomes of patients undergone total hip and knee arthroplasty (THA & TKA) and hip fracture surgeries.

Background

Previous systematic reviews examined components and effectiveness of ICPs for lower limb joint replacement and hip fracture surgeries.

Design and Methods

An updated systematic review guided by the Whittemore and Knafl (2005) framework. Electronic databases, Ovid MEDLINE, EBSCOhost-CINAHL, the Cochrane Reviews and Trails, EMBASE and PubMed, were searched from 2007 to 31 January 2021. Due to the heterogeneity of the methods and data collection …


Tourists' Perceptions Of And Reactions To Child Sex Tourism: An Exploratory Qualitative Investigation, Joshua Aston, Jun Wen, Shaohua Yang Jan 2023

Tourists' Perceptions Of And Reactions To Child Sex Tourism: An Exploratory Qualitative Investigation, Joshua Aston, Jun Wen, Shaohua Yang

Research outputs 2022 to 2026

Purpose: Using a qualitative approach, this cross-disciplinary study integrating modern slavery, tourism and marketing expertise outlines Chinese outbound tourists' perceptions of and reactions to issues related to child sex tourism.

Design/methodology/approach: In total, 27 in-depth interviews were conducted, and data were analysed. Manual coding was chosen as an efficient method to process qualitative interview data given the relatively small sample size in this study.

Findings: Three main themes emerged from analysis: (1) tourists' negative perceptions of child sex tourism; (2) tourist boycotts against child sex tourism destinations and activities as reactions to this socially deviant and illegal phenomenon and (3) …


Nursing Students Doing Gender: Implications For Higher Education And The Nursing Profession, Lesley J. Andrew, Ken Robinson, Julie Dare, Leesa N. Costello Jan 2023

Nursing Students Doing Gender: Implications For Higher Education And The Nursing Profession, Lesley J. Andrew, Ken Robinson, Julie Dare, Leesa N. Costello

Research outputs 2022 to 2026

The average age of women nursing students in Australia is rising. With this comes the likelihood that more now begin university with family responsibilities, and with their lives structured by the roles of mother and partner. Women with more traditionally gendered ideas of these roles, such as nurturing others and self-sacrifice, are known to be attracted to nursing as a profession; once at university, however, these students can be vulnerable to gender role stress from the competing demands of study. A qualitative research design, guided by Gadamer's hermeneutic philosophy, explored the gendered behaviours and experiences of 22 women nursing students, …


Autonomy Versus Support: Self-Reliance And Help-Seeking For Mental Health Problems In Young People, Amelia Ishikawa, Debra Rickwood, Emily Bariola, Navjot Bhullar Jan 2023

Autonomy Versus Support: Self-Reliance And Help-Seeking For Mental Health Problems In Young People, Amelia Ishikawa, Debra Rickwood, Emily Bariola, Navjot Bhullar

Research outputs 2022 to 2026

Purpose:

Many young people with mental ill-health do not seek support, and developmental growth in self-reliance may be a barrier to help-seeking. Increasing autonomy is a positive developmental task for youth and a key aspect of resilience. This study examined the influence of perceived social support and resilience on the previously unexamined relationship between self-reliance and intentions to seek help from informal, professional, and self-help sources for mental health problems.

Methods:

An online survey was completed by a representative Australian community sample of 5,203 young people aged 12–25 years (half female), in May–June 2020.

Results:

Path analysis showed the hypothesised …


Do Physiological Variables Predict The Need For Transport To Hospital From Music Festivals? An Analysis Of Australian Festival Data, Ned Douglas, Jake Donovan, James Carew, Kayla Brouwer, Ebony Edwards, Mitchell Gibson, Jacqueline Leverett, Joseph Paul, Lachlan Holbery-Morgan, Jessica Pritchard, Elyssia Bourke, Erin Smith Jan 2023

Do Physiological Variables Predict The Need For Transport To Hospital From Music Festivals? An Analysis Of Australian Festival Data, Ned Douglas, Jake Donovan, James Carew, Kayla Brouwer, Ebony Edwards, Mitchell Gibson, Jacqueline Leverett, Joseph Paul, Lachlan Holbery-Morgan, Jessica Pritchard, Elyssia Bourke, Erin Smith

Research outputs 2022 to 2026

Objective:

Using physiological markers to detect patients at risk of deterioration is common. Deaths at music festivals in Australia prompted scrutiny of tools to identify critically unwell patients for transport to hospital. This study evaluated initial physiological parameters to identify patients selected for transport to hospital from a music festival.

Methods:

A retrospective audit of 2045 presentations at music festivals in Victoria, Australia, was performed. Presentation heart rate, systolic blood pressure, respiratory rate, oxygen saturation, temperature, and Glasgow Coma Scale were assessed using area under the receiver operating characteristic curve (AUROC) analysis, with a prespecified threshold of 0.7.

Results:

The …


Managing Emotional Labour: The Importance Of Organisational Support For Managing Police Officers In England And Italy, Yvonne Brunetto, Ben Farr-Wharton, Paresh Wankhade, Chiara Saccon, Matthew Xerri Jan 2023

Managing Emotional Labour: The Importance Of Organisational Support For Managing Police Officers In England And Italy, Yvonne Brunetto, Ben Farr-Wharton, Paresh Wankhade, Chiara Saccon, Matthew Xerri

Research outputs 2022 to 2026

This paper empirically examines the impact of organisational psychological support on employees’ outcomes as an example of the ‘Common Good HRM’ model on the well-being–performance continuum of police officers, using a Conservation of Resources (COR) theoretical framework. The study uses Structural Equation Modelling to analyse data from 220 Italian police and 228 English police officers to compare the impact of Perceived Organisational Support (POS) on organisational stress, employees’ resilience, and engagement. The findings show that low Perceived Organisational Support (POS) leads to high stress, which then comprises employees’ resilience and likely demotivates them from being engaged on the job, explaining …


Principles And Philosophies For Speech And Language Therapists Working With People With Primary Progressive Aphasia: An International Expert Consensus, A. Volkmer, J. Cartwright, L. Ruggero, A. Beales, J. Gallée, S. Grasso, M. Henry, R. Jokel, J. Kindell, R. Khayum, M. Pozzebon, E. Rochon, C. Taylor-Rubin, R. Townsend, F. Walker, S. Beeke, Deborah Hersh Jan 2023

Principles And Philosophies For Speech And Language Therapists Working With People With Primary Progressive Aphasia: An International Expert Consensus, A. Volkmer, J. Cartwright, L. Ruggero, A. Beales, J. Gallée, S. Grasso, M. Henry, R. Jokel, J. Kindell, R. Khayum, M. Pozzebon, E. Rochon, C. Taylor-Rubin, R. Townsend, F. Walker, S. Beeke, Deborah Hersh

Research outputs 2022 to 2026

Purpose:

Primary progressive aphasia (PPA) is a language-led dementia associated with Alzheimer’s pathology and fronto-temporal lobar degeneration. Multiple tailored speech and language interventions have been developed for people with PPA. Speech and language therapists/speech-language pathologists (SLT/Ps) report lacking confidence in identifying the most pertinent interventions options relevant to their clients living with PPA during their illness trajectory.

Materials and methods:

The aim of this study was to establish a consensus amongst 15 clinical-academic SLT/Ps on best practice in selection and delivery of speech and language therapy interventions for people with PPA. An online nominal group technique (NGT) and consequent focus …


‘It Was Just As Political As It Was Pragmatic’: The (In)Formal Roles And Policy Work Of ‘Curriculum Leaders’ In A Federated Education Context, Karen Lambert, Dawn Penney Jan 2023

‘It Was Just As Political As It Was Pragmatic’: The (In)Formal Roles And Policy Work Of ‘Curriculum Leaders’ In A Federated Education Context, Karen Lambert, Dawn Penney

Research outputs 2022 to 2026

Politics and pragmatics are central and inseparable features of curriculum reform. In a federated system like Australia, many individuals and organisations are invested in reform at the national and jurisdictional level. This paper focuses on the policy work and roles of key actors positioned at the interface of national and state-based curriculum development, and at the juncture of curriculum policy and pedagogic practice. These were individuals formally identified as ‘curriculum leaders’ in the enactment of the Australian Curriculum in Health and Physical Education (ACHPE). The paper centres on data collected from eight (n = 8) curriculum leaders via semi-structured interviews. …


Investigating The Perspectives Of Older Adults In Residential Aged Care On Oral Health-Related Quality Of Life, Parisa Malekpour, Amanda Devine, Julie Dare, Leesa Costello Jan 2023

Investigating The Perspectives Of Older Adults In Residential Aged Care On Oral Health-Related Quality Of Life, Parisa Malekpour, Amanda Devine, Julie Dare, Leesa Costello

Research outputs 2022 to 2026

Objective

The objective of the study was to explore how older people living in a residential aged care facility perceived that their oral health influenced their food preferences and attitudes towards food, their social interactions and their self-esteem.

Background

Poor oral health can have biological, behavioural and social impacts on quality of life among older adults (aged 65+ years). In terms of biological impacts, oral health impairments may cause older adults to avoid many types of foods. This shift in dietary pattern can lead to malnutrition among older people, undermine general health and negatively impact quality of life (QOL).

Materials …


With Great Power Comes Great Responsibility: Common Errors In Meta-Analyses And Meta-Regressions In Strength & Conditioning Research, Daniel Kadlec, Kristin L. Sainani, Sophia Nimphius Jan 2023

With Great Power Comes Great Responsibility: Common Errors In Meta-Analyses And Meta-Regressions In Strength & Conditioning Research, Daniel Kadlec, Kristin L. Sainani, Sophia Nimphius

Research outputs 2022 to 2026

Background and Objective:

Meta-analysis and meta-regression are often highly cited and may influence practice. Unfortunately, statistical errors in meta-analyses are widespread and can lead to flawed conclusions. The purpose of this article was to review common statistical errors in meta-analyses and to document their frequency in highly cited meta-analyses from strength and conditioning research.

Methods:

We identified five errors in one highly cited meta-regression from strength and conditioning research: implausible outliers; overestimated effect sizes that arise from confusing standard deviation with standard error; failure to account for correlated observations; failure to account for within-study variance; and a focus on within-group …


Perceptions And Experiences Of Career Success Among Aspiring And Early Career Accountants And The Role Of Organisational Support, Denise Jackson, Julia Richardson, Grant Michelson, Rahat Munir Jan 2023

Perceptions And Experiences Of Career Success Among Aspiring And Early Career Accountants And The Role Of Organisational Support, Denise Jackson, Julia Richardson, Grant Michelson, Rahat Munir

Research outputs 2022 to 2026

Positive perceptions of career success are critical among accounting professionals, given their connection with performance, turnover and organisational commitment. Drawing on career stage theory, this study explores the perceptions and experiences of career success among 475 aspiring (Accounting/Finance students), 305 early career accountants (ECAs) and 165 managers/recruiters in Australia. Findings reflected both objective and subjective dimensions of career success alongside notable differences between aspiring accountants and ECAs, highlighting shifting views across the career stages of exploration and establishment. While ECAs were largely positive about their access to career success, managers/recruiters identified ways to create further opportunities for ECAs' career success.


Does High-Velocity Resistance Exercise Elicit Greater Physical Function Benefits Than Traditional Resistance Exercise In Older Adults? A Systematic Review And Network Meta-Analysis Of 79 Trials, Pedro Lopez, Anderson Rech, Maria Petropoulou, Robert Newton, Dennis Taaffe, Daniel A. Galvão, Douglas P. J. Turella, Sandro R. Freitas, Régis Radaelli Jan 2023

Does High-Velocity Resistance Exercise Elicit Greater Physical Function Benefits Than Traditional Resistance Exercise In Older Adults? A Systematic Review And Network Meta-Analysis Of 79 Trials, Pedro Lopez, Anderson Rech, Maria Petropoulou, Robert Newton, Dennis Taaffe, Daniel A. Galvão, Douglas P. J. Turella, Sandro R. Freitas, Régis Radaelli

Research outputs 2022 to 2026

Background

A systematic review and network meta-analysis was undertaken to examine the effectiveness of different modes of resistance exercise velocity in fast walking speed, timed-up and go, 5-times sit-to-stand, 30-second sit-to-stand, and 6-minute walking tests in older adults.

Methods

CINAHL, Embase, LILACS, PubMed, Scielo, SPORTDiscus, and Web of Science databases were searched up to February 2022. Eligible randomized trials examined the effects of supervised high-velocity or traditional resistance exercise in older adults (ie, ≥ 60 years). The primary outcome for this review was physical function measured by fast walking speed, timed-up and go, 5-times sit-to-stand, 30-second sit-to-stand, and 6-minute walking …


Impact Of Work-Integrated Learning And Co-Curricular Activities On Graduate Labour Force Outcomes, Denise Jackson, Anna Rowe Jan 2023

Impact Of Work-Integrated Learning And Co-Curricular Activities On Graduate Labour Force Outcomes, Denise Jackson, Anna Rowe

Research outputs 2022 to 2026

The explicit linking of institutional funding to in-curricular industry engagement and graduate employment affirms the strategic importance of enhancing graduate employability in Australia. Key strategies to enhance graduate employability and employment outcomes are work-integrated learning (WIL) (where students engage with industry as part of their formal learning and assessment) and co-curricular activities (e.g. volunteering, leadership/award, and mentoring programmes), which are facilitated by the university but not embedded into curricula. While WIL is widely recognised for enhancing different aspects of student employability, the impact of co-curricular activities is less well-known. Further, there is a lack of empirical analysis on the nuanced …


Decoding The Mechanism Of Hypertension Through Multiomics Profiling, Eric Adua Jan 2023

Decoding The Mechanism Of Hypertension Through Multiomics Profiling, Eric Adua

Research outputs 2022 to 2026

Hypertension, characterised by a constant high blood pressure, is the primary risk factor for multiple cardiovascular events and a major cause of death in adults. Excitingly, innovations in high-throughput technologies have enabled the global exploration of the whole genome (genomics), revealing dysregulated genes that are linked to hypertension. Moreover, post-genomic biomarkers, from the emerging fields of transcriptomics, proteomics, glycomics and lipidomics, have provided new insights into the molecular underpinnings of hypertension. In this paper, we review the pathophysiology of hypertension, and highlight the multi-omics approaches for hypertension prediction and diagnosis.


Patterns And Implications Of Neurological Examination Findings In Autosomal Dominant Alzheimer Disease, Jonathan Vöglein, Nicolai Franzmeier, John C. Morris, Marianne Dieterich, Eric Mcdade, Mikael Simons, Oliver Preische, Anna Hofmann, Jason Hassenstab, Tammie L. Benzinger, Anne Fagan, James M. Noble, Sarah B. Berman, Neill R. Graff-Radford, Bernardino Ghetti, Martin R. Farlow, Jasmeer P. Chhatwal, Stephen Salloway, Chengjie Xiong, Celeste M. Karch, Nigel Cairns, Richard J. Perrin, Gregory Day, Ralph Martins, Raquel Sanchez-Valle, Hiroshi Mori, Hiroyuki Shimada, Takeshi Ikeuchi, Kazushi Suzuki, Peter R. Schofield, Colin L. Masters, Alison Goate, Virginia Buckles, Nick C. Fox, Patricio Chrem, Ricardo Allegri, John M. Ringman, Igor Yakushev, Christoph Laske, Mathias Jucker, Günter Höglinger, Randall L. Bateman, Adrian Danek, Johannes Levin, Dominantly Inherited Alzheimer Network Jan 2023

Patterns And Implications Of Neurological Examination Findings In Autosomal Dominant Alzheimer Disease, Jonathan Vöglein, Nicolai Franzmeier, John C. Morris, Marianne Dieterich, Eric Mcdade, Mikael Simons, Oliver Preische, Anna Hofmann, Jason Hassenstab, Tammie L. Benzinger, Anne Fagan, James M. Noble, Sarah B. Berman, Neill R. Graff-Radford, Bernardino Ghetti, Martin R. Farlow, Jasmeer P. Chhatwal, Stephen Salloway, Chengjie Xiong, Celeste M. Karch, Nigel Cairns, Richard J. Perrin, Gregory Day, Ralph Martins, Raquel Sanchez-Valle, Hiroshi Mori, Hiroyuki Shimada, Takeshi Ikeuchi, Kazushi Suzuki, Peter R. Schofield, Colin L. Masters, Alison Goate, Virginia Buckles, Nick C. Fox, Patricio Chrem, Ricardo Allegri, John M. Ringman, Igor Yakushev, Christoph Laske, Mathias Jucker, Günter Höglinger, Randall L. Bateman, Adrian Danek, Johannes Levin, Dominantly Inherited Alzheimer Network

Research outputs 2022 to 2026

Introduction:

As knowledge about neurological examination findings in autosomal dominant Alzheimer disease (ADAD) is incomplete, we aimed to determine the frequency and significance of neurological examination findings in ADAD.

Methods:

Frequencies of neurological examination findings were compared between symptomatic mutation carriers and non mutation carriers from the Dominantly Inherited Alzheimer Network (DIAN) to define AD neurological examination findings. AD neurological examination findings were analyzed regarding frequency, association with and predictive value regarding cognitive decline, and association with brain atrophy in symptomatic mutation carriers.

Results:

AD neurological examination findings included abnormal deep tendon reflexes, gait disturbance, pathological cranial nerve examination findings, …


Plasma Aβ42/40 Ratio, P-Tau181, Gfap, And Nfl Across The Alzheimer's Disease Continuum: A Cross-Sectional And Longitudinal Study In The Aibl Cohort, Pratishtha Chatterjee, Steve Pedrini, James D. Doecke, Rohith Thota, Victor L. Villemagne, Vincent Doré, Abhay K. Singh, Penghao Wang, Stephanie Rainey-Smith, Christopher Fowler, Kevin Taddei, Hamid R. Sohrabi, Mark P. Molloy, David Ames, Paul Maruff, Christopher C. Rowe, Colin L. Masters, Ralph N. Martins, Aibl Research Group Jan 2023

Plasma Aβ42/40 Ratio, P-Tau181, Gfap, And Nfl Across The Alzheimer's Disease Continuum: A Cross-Sectional And Longitudinal Study In The Aibl Cohort, Pratishtha Chatterjee, Steve Pedrini, James D. Doecke, Rohith Thota, Victor L. Villemagne, Vincent Doré, Abhay K. Singh, Penghao Wang, Stephanie Rainey-Smith, Christopher Fowler, Kevin Taddei, Hamid R. Sohrabi, Mark P. Molloy, David Ames, Paul Maruff, Christopher C. Rowe, Colin L. Masters, Ralph N. Martins, Aibl Research Group

Research outputs 2022 to 2026

Introduction:

Plasma amyloid beta (Aβ)1-42/Aβ1-40 ratio, phosphorylated-tau181 (p-tau181), glial fibrillary acidic protein (GFAP), and neurofilament light (NfL) are putative blood biomarkers for Alzheimer's disease (AD). However, head-to-head cross-sectional and longitudinal comparisons of the aforementioned biomarkers across the AD continuum are lacking.

Methods:

Plasma Aβ1-42, Aβ1-40, p-tau181, GFAP, and NfL were measured utilizing the Single Molecule Array (Simoa) platform and compared cross-sectionally across the AD continuum, wherein Aβ-PET (positron emission tomography)–negative cognitively unimpaired (CU Aβ−, n = 81) and mild cognitive impairment (MCI Aβ−, n = 26) participants were compared with Aβ-PET–positive participants across the AD continuum (CU Aβ+, n = …


Metal-Organic Framework-Based Biosensing Platforms For The Sensitive Determination Of Trace Elements And Heavy Metals: A Comprehensive Review, Hessamaddin Sohrabi, Shahin Ghasemzadeh, Sama Shakib, Mir Reza Majidi, Amir Razmjou, Yeojoon Yoon, Alireza Khataee Jan 2023

Metal-Organic Framework-Based Biosensing Platforms For The Sensitive Determination Of Trace Elements And Heavy Metals: A Comprehensive Review, Hessamaddin Sohrabi, Shahin Ghasemzadeh, Sama Shakib, Mir Reza Majidi, Amir Razmjou, Yeojoon Yoon, Alireza Khataee

Research outputs 2022 to 2026

Heavy metals in food and water sources are potentially harmful to humans. Determination of these pollutants is critical for improving safety. Effective recognition systems are a contemporary challenge; several novel technologies for the quick, easy, selective, and sensitive determination of these compounds are in demand. Metal-organic framework (MOF)-based sensors and biosensors have crucial applications in identifying these potentially harmful substances. Here, we review electrochemical and optical biosensors for in situ sensing that are sensitive and cost effective, with a simple protocol and wide linear range. Despite the abundance of articles in this field, we assessed and checked out various basic …


Association Of Igg N-Glycomics With Prevalent And Incident Type 2 Diabetes Mellitus From The Paradigm Of Predictive, Preventive, And Personalized Medicine Standpoint, Xiaoni Meng, Fei Wang, Xiangyang Gao, Biyan Wang, Xizhu Xu, Youxin Wang, Wei Wang, Qiang Zeng Jan 2023

Association Of Igg N-Glycomics With Prevalent And Incident Type 2 Diabetes Mellitus From The Paradigm Of Predictive, Preventive, And Personalized Medicine Standpoint, Xiaoni Meng, Fei Wang, Xiangyang Gao, Biyan Wang, Xizhu Xu, Youxin Wang, Wei Wang, Qiang Zeng

Research outputs 2022 to 2026

Objectives: Type 2 diabetes mellitus (T2DM), a major metabolic disorder, is expanding at a rapidly rising worldwide prevalence and has emerged as one of the most common chronic diseases. Suboptimal health status (SHS) is considered a reversible intermediate state between health and diagnosable disease. We hypothesized that the time frame between the onset of SHS and the clinical manifestation of T2DM is the operational area for the application of reliable risk assessment tools, such as immunoglobulin G (IgG) N-glycans. From the viewpoint of predictive, preventive, and personalized medicine (PPPM/3PM), the early detection of SHS and dynamic monitoring by glycan biomarkers …