Digital Commons Network^™

The Twenty-Five Maiden Ladies’ Tomb And Predicaments Of The Feminist Movement In Taiwan, Anru Lee

Publications and Research

No abstract provided.

How Subways And High Speed Railways Have Changed Taiwan: Transportation Technology, Urban Culture, And Social Life, Anru Lee

Publications and Research

No abstract provided.

Real Time Imaging Of Biomarkers In The Parkinson's Brain Using Mini-Implantable Biosensors. Ii. Pharmaceutical Therapy With Bromocriptine, Patricia A. Broderick, Edwin H. Kolodny

Publications and Research

We used Neuromolecular Imaging (NMI) and trademarked BRODERICK PROBE® mini-implantable biosensors, to selectively and separately detect neuro-transmitters in vivo, on line, within seconds in the dorsal striatal brain of the Parkinson’s Disease (PD) animal model. We directly compared our results derived from PD to the normal striatal brain of the non-Parkinson’s Disease (non-PD) animal. This advanced biotechnology enabled the imaging of dopamine (DA), serotonin (5-HT), homovanillic acid (HVA) a metabolite of DA, L-tryptophan (L-TP) a precursor to 5-HT and peptides, dynorphin A 1-17 (Dyn A) and somatostatin (somatostatin releasing inhibitory factor) (SRIF). Each neurotransmitter and neurochemical was imaged at a …

The Messy Teaching Conversation: Toward A Model Of Collegial Reflection, Exchange, And Scholarship On Classroom Problems, Heidi L. Johnsen, Michelle Pacht, Phyllis E. Vanslyck, Ting Man Tsao

Publications and Research

Whether we teach in junior or senior colleges, we often represent our teaching in the best possible light, leaving little room for acknowledgment or discussion of uncertainty or errors. It seems that the only way to discuss a set back is as part of a larger narrative, one where a failure is simply a precursor to success, a way of highlighting a challenge overcome.This wall of silence about our "messes" prevents us from honestly discussing our day-to-day work in the classroom. This article models just such a "messy teaching conversation."

Linkage Among U.S. Interest Rates And East Asian Purchases Of U.S. Treasury Securities, Dene T. Hurley Dr.

Publications and Research

Recent increases in East Asian purchases of US treasury securities has led to growing concern over its impact on the US economy, particularly on the US long-term and shortterm interest rates. The vector error-correction model results revealed the presence of long-run causal relations among the federal funds rate, the 10-year Treasury rate and the East Asian demand in addition to a unidirectional short-run causal relation from the 10-year rate to the Federal funds rate. The variance decomposition and impulse response findings indicated that the Asian demand for US assets has a limited but negative impact on the 10-year US Treasury …

Nonknowledge: The Bibliographical Organization Of Ignorance, Stupidity, Error, And Unreason: Part Two, Jay H. Bernstein

Publications and Research

Starting with the Data-Information-Knowledge-Wisdom paradigm in information science it is possible to derive a model of the opposite of knowledge having hierarchical qualities. A range of counterpoints to concepts in the knowledge hierarchy can be identified and ascribed the overall term “nonknowledge.” This model creates a conceptual framework for understanding the connections between topics such as error, ignorance, stupidity, folly, popular misconceptions, and unreason by locating them as levels or phases of nonknowledge. The concept of nonknowledge links heretofore disconnected discourses on these individual topics by philosophers, psychologists, historians, sociologists, satirists, and others. Subject headings provide access to the categories …

Road Show (Review), Alisa Roost

Publications and Research

No abstract provided.

Radical Theatricality: Jongleuresque Performance On The Early Spanish Stage, Christopher B. Swift

Publications and Research

Radical Theatricality describes medieval and early modern oral traditions through the culture of “jongleuresque” performers: juglares, trovadores, and other itinerant players, who have been relegated to the fringes of theatre history.

Egg Eviction Imposes A Recoverable Cost Of Virulence In Chicks Of A Brood Parasite, Michael G. Anderson, Csaba Moskát, Miklós Bán, Tomáš Grim, Phillip Cassey, Mark E. Hauber

Publications and Research

Background Chicks of virulent brood parasitic birds eliminate their nestmates and avoid costly competition for foster parental care. Yet, efforts to evict nest contents by the blind and naked common cuckoo Cuculus canorus hatchling are counterintuitive as both adult parasites and large older cuckoo chicks appear to be better suited to tossing the eggs and young of the foster parents. Methodology/Principal Findings Here we show experimentally that egg tossing imposed a recoverable growth cost of mass gain in common cuckoo chicks during the nestling period in nests of great reed warbler Acrocephalus arundinaceus hosts. Growth rates of skeletal traits and …

Contexts Of Exit In The Migration Of Russian Speakers From The Baltic Countries To Ireland, Sofya Aptekar

Publications and Research

Recently, Ireland has become a major destination for migrants from Estonia, Latvia, and Lithuania. Many of these migrants are members of Russian-speaking minorities leaving a context of restrictive citizenship and language laws and varying degrees of ethnic tension. This paper draws on interviews collected in Ireland to examine the role played by the contexts of exit in decisions to migrate among Russian-speaking minorities from the Baltics. The results suggest that Russian speakers from Estonia migrate because of their experiences as minorities, while those from Latvia and Lithuania migrate to escape low wages and irregular employment. This is so despite equally …

Correlating Molecular Phylogeny With Venom Apparatus Occurrence In Panamic Auger Snails (Terebridae), Mandë Holford, Nicolas Puillandre, Maria Vittoria Modica, Maren Watkins, Rachel Collin, Eldredge Bermingham, Baldomero M. Olivera

Publications and Research

Central to the discovery of neuroactive compounds produced by predatory marine snails of the superfamily Conoidea (cone snails, terebrids, and turrids) is identifying those species with a venom apparatus. Previous analyses of western Pacific terebrid specimens has shown that some Terebridae groups have secondarily lost their venom apparatus. In order to efficiently characterize terebrid toxins, it is essential to devise a key for identifying which species have a venom apparatus. The findings presented here integrate molecular phylogeny and the evolution of character traits to infer the presence or absence of the venom apparatus in the Terebridae. Using a combined dataset …

Mercury Exposure, Nutritional Deficiencies And Metabolic Disruptions May Affect Learning In Children, Renee Dufault, Roseanne Schnoll, Walter J. Lukiw, Blaise Leblanc, Charles Cornett, Lyn Patrick, David Wallinga, Steven G. Gilbert, Raquel Crider

Publications and Research

Among dietary factors, learning and behavior are influenced not only by nutrients, but also by exposure to toxic food contaminants such as mercury that can disrupt metabolic processes and alter neuronal plasticity. Neurons lacking in plasticity are a factor in neurodevelopmental disorders such as autism and mental retardation. Essential nutrients help maintain normal neuronal plasticity. Nutritional deficiencies, including deficiencies in the long chain polyunsaturated fatty acids eicosapentaenoic acid and docosahexaenoic acid, the amino acid methionine, and the trace minerals zinc and selenium, have been shown to influence neuronal function and produce defects in neuronal plasticity, as well as impact behavior …

The Accounting At A Tipping Point – Decline Or Renewal, Susan Haka

Publications and Research

No abstract provided.

Organizational Life And Political Incorporation Of Two Asian Immigrant Groups: A Case Study, Sofya Aptekar

Publications and Research

Civil society is the foundation of a healthy democracy but its immigrant element has received little attention. This paper is a case study of immigrant organizations of highly skilled Asian Indians and Chinese immigrants in a suburban town of Edison, New Jersey. I find that civic participation of Asian Indian immigrants spills over into political incorporation while Chinese immigrant organizations remain margin- alized. I argue that local processes of racialization are central in explaining differences in political incorporation of immigrants. In the local context, the Chinese are seen as successful but conformist model minorities and Asian Indians as invaders and …

Cooperative Social Clusters Are Not Destroyed By Dispersal In A Ciliate, Nicolas Schtickzelle, Else J. Fjerdingstad, Alexis Chaine, Jean Clobert

Publications and Research

Background The evolution of social cooperation is favored by aggregative behavior to facilitate stable social structure and proximity among kin. High dispersal rates reduce group stability and kin cohesion, so it is generally assumed that there is a fundamental trade-off between cooperation and dispersal. However, empirical tests of this relationship are rare. We tested this assumption experimentally using ten genetically isolated strains of a ciliate, Tetrahymena thermophila. Results The propensity for social aggregation was greater in strains with reduced cell quality and lower growth performance. While we found a trade-off between costly aggregation and local dispersal in phenotypic analyses, aggregative …

Activation Of Cyclin-Dependent Kinase 5 Is A Consequence Of Cell Death, Yixia Ye, Antonella Tinari, Walter Malorni, Zahra Zakeri

Publications and Research

Cyclin-dependent kinase 5 (Cdk5) is similar to other Cdks but is activated during cell differentiation and cell death rather than cell division. Since activation of Cdk5 has been reported in many situations leading to cell death, we attempted to determine if it was required for any form of cell death. We found that Cdk5 is activated during apoptotic deaths and that the activation can be detected even when the cells continue to secondary necrosis. This activation can occur in the absence of Bim, calpain, or neutral cathepsins. The kinase is typically activated by p25, derived from p35 by calpain-mediated cleavage, …

Comparison Of Spatial Summation Properties Of Neurons In Macaque V1 And V2, S. Shushruth, Jennifer M. Ichida, Jonathan B. Levitt, Alessandra Angelucci

Publications and Research

In visual cortex, responses to stimulation of the receptive field (RF) are modulated by simultaneous stimulation of the RF surround. The mechanisms for surround modulation remain unidentified. We previously proposed that in the primary visual cortex (V1), near surround modulation is mediated by geniculocortical and horizontal connections and far surround modulation by interareal feedback connections. To understand spatial integration in the secondary visual cortex (V2) and its underlying circuitry, we have characterized spatial summation in different V2 layers and stripe compartments and compared it to that in V1. We used grating stimuli in circular and annular apertures of different sizes …

Cooperation Between A Coenzyme A-Independent Stand-Alone Initiation Module And An Iterative Type I Polyketide Synthase During Synthesis Of Mycobacterial Phenolic Glycolipids, Weiguo He, Clifford E. Soll, Sivagami Sundaram Chavadi, Guangtao Zhang, J. David Warren, Luis E. N. Quadri

Publications and Research

Several Mycobacterium tuberculosis strains, Mycobacterium leprae, and other mycobacterial pathogens produce a group of small-molecule virulence factors called phenolic glycolipids (PGLs). PGLs play key roles in pathogenicity and host−pathogen interaction. Thus, elucidation of the PGL biosynthetic pathway will not only expand our understanding of natural product biosynthesis, but may also illuminate routes to novel therapeutics to afford alternative lines of defense against mycobacterial infections. In this study, we report an investigation of the enzymatic requirements for the production of long-chain p-hydroxyphenylalkanoate intermediates of PGL biosynthesis. We demonstrate a functional cooperation between a coenzyme A-independent stand-alone didomain initiation module (FadD22) and …

Extra, Extra, Read All About It!, Irvin Sam Schonfeld

Publications and Research

No abstract provided.

Ron’S Right Arm: Tactility, Visualization, And The Synesthesia Of Audio Engineering, Eliot Bates

Publications and Research

Most scholarship on audio engineering analyzes practices and practitioners in terms of musical and technical knowledges. The few references to sensory perception typically center on critical listening practices (“golden ears” engineers), audiophilia, and technologies of audition. However, particularly in light of computer-based workflows, the practice of audio engineering features carefully developed synesthesias of critical listening, visualization of digital audio, and tactile manipulations of interfaces, which can’t adequately be explained as cognitive processes or as conscious knowledge.

I draw on literature in the emerging field of sensory scholarship, in particular Brian Massumi’s theorization of synesthesia and affect and Charles Hirschkind’s analyses …

Identifying Publication Outlets In Occupational Health Psychology: An Opinion Survey, Maria Karanika-Murray, Irvin Sam Schonfeld, Leigh Schmitt

Publications and Research

No abstract provided.

Untangling The Relationship Between Libraries, Young Adults And Web 2.0: The Necessity Of A Critical Perspective, Lucia Cedeira Serantes

Publications and Research

Purpose: This paper addresses a gap in the analysis of the dynamic and challenging relationship between libraries, Web 2.0 and young adults, suggesting the relevance of a critical approach.

Methodology/Approach: This paper represents an exploratory literature review with the objective of identifying a possible gap in the way the LIS community is addressing the concept of Web 2.0.

Findings: Findings indicate that the research produced in other fields, such as Communication or Computer Science; the way young adults interrelate with new technologies; and the need for collaboration between practitioners and researchers justify and support the use of a critical perspective …

A Randomised-Controlled Trial Of Two Educational Modes For Undergraduate Evidence-Based Medicine Learning In Asia, Janice M. Johnston, Mary Schooling, Gabriel M. Leung

Publications and Research

Background
As the overall evidence for the effectiveness of teaching of evidence based medicine (EBM) is not strong, and the impact of cultural and societal influences on teaching method is poorly understood, we undertook a randomised-controlled trial to test the effectiveness and learning satisfaction with two different EBM teaching methods (usual teaching vs. problem based learning (PBL)) for undergraduate medical students.

Methods
A mixed methods study that included a randomised-controlled crossover trial with two intervention arms (usual teaching and PBL) and a nested qualitative study with focus groups to explore student perceptions of learning and to assess the effectiveness and …

Optimizing Taq Polymerase Concentration For Improved Signal-To-Noise In The Broad Range Detection Of Low Abundance Bacteria, Rudolph Spangler, Noel L. Goddard, David S. Thaler

Publications and Research

Background PCR in principle can detect a single target molecule in a reaction mixture. Contaminating bacterial DNA in reagents creates a practical limit on the use of PCR to detect dilute bacterial DNA in environmental or public health samples. The most pernicious source of contamination is microbial DNA in DNA polymerase preparations. Importantly, all commercial Taq polymerase preparations inevitably contain contaminating microbial DNA. Removal of DNA from an enzyme preparation is problematical. Methodology/Principal Findings This report demonstrates that the background of contaminating DNA detected by quantitative PCR with broad host range primers can be decreased greater than 10-fold through the …

The Evaluation Of Use Of Electronic Resources And Services In Academic Libraries: A Study Of E-Metrics And Related Methods For Measurement And Assessment, Kanu A. Nagra

Publications and Research

This paper presents a review of literature for the evaluation of use of electronic resources and services in Academic libraries. E-metrics and similar methods for evaluation are discussed in detail. The paper highlights how some libraries approached e-metrics to start useful evaluations and dealt with technicalities to achieve better decision making for e-collection, services and infrastructure for their library users. The evaluation of use of e-resources and services is discussed in five parts explaining application of e-metrics, different methods to capture usage data in different settings, types of data requirement by libraries, complexities and technicalities involved in measurement of usage …

The Impact Of Socioeconomic Status On The Neural Substrates Associated With Pleasure, Michael E. Silverman, Peter Muennig, Xun Liu, Zohn Rosen, Martin A. Goldstein

Publications and Research

Low socio-economic status (SES) is associated with increased morbidity and premature mortality. Because tonic adversity relates to a diminished ability to experience pleasure, we hypothesized that subjects living in poverty would show diminished neural responsivity to positive stimuli in regions associated with positive experience and reward. Visual images were presented to twenty-two subjects in the context of a EPI-BOLD fMRI paradigm. Significant differences in neural responses between SES groups to poverty vs. neutral images were assessed, examining group, condition, and interaction effects. The data suggest that persons living in low-SES have neural experiences consistent with diminished interest in things generally …

Subchronic Infusion Of The Product Of Inflammation Prostaglandin J2 Models Sporadic Parkinson's Disease In Mice, Sha-Ron Pierre, Marijke Am Lemmens, Maria E. Figueiredo-Pereira

Publications and Research

Background Chronic neuroinflammation is implicated in Parkinson's disease (PD). Inflammation involves the activation of microglia and astrocytes that release high levels of prostaglandins. There is a profound gap in our understanding of how cyclooxygenases and their prostaglandin products redirect cellular events to promote PD neurodegeneration. The major prostaglandin in the mammalian brain is prostaglandin D2, which readily undergoes spontaneous dehydration to generate the bioactive cyclopentenone prostaglandins of the J2 series. These J2 prostaglandins are highly reactive and neurotoxic products of inflammation shown in cellular models to impair the ubiquitin/proteasome pathway and cause the accumulation of ubiquitinated proteins. PD is a …

Growth And Differentiation Of The Larval Mosquito Midgut, Kathryn Ray, Maria Mercedes, Doris Chan, Chi Yan Choi, James T. Nishiura

Publications and Research

Factors affecting larval growth and nutrition have consequences on adult fecundity. Since the mosquito larval midgut is the primary organ of digestion and nutrient absorption, factors that affect the growth and development of the midgut may have potential consequences on the reproductive potential of the adult. To gain a better understanding of mosquito midgut development the growth and metamorphic remodeling of the Aedes aegypti L. and Culex pipiens L. (Diptera: Culicidae) midguts were investigated. Cytological evidence was obtained suggesting that, in both the anterior and posterior Ae. aegypti larval midgut, diploid regenerative cells give rise to new endoreplicating cells that …

Securing An Effective Voice For Citizens In Intergovernmental Administrative Decision Making, Maria J. D'Agostino

Publications and Research

Intergovernmental administrative arrangements, often obscured from public view, are responsible for public decisions and their consequences. After European Union citizens expressed dissatisfaction with the disconnected administrative decision-making process by rejecting the European Constitution, the European Commission called for a period of reflection to develop tools and processes in order to involve citizens in the decision-making process.

This article examines collaborative efforts by the European Union to involve citizens in the shaping of national priorities. In-depth interviews were conducted with the heads of nonprofit organizations and staffers at nonprofits involved with organizing the European Citizens’ Consultations (ECC). All the organizations are …

Teaching Mathematics For Social Justice: Reflections On A Community Of Practice For Urban High School Mathematics Teacher, Lidia Gonzalez

Publications and Research

In this article, the author reports on a study that explored, in part, the developing identities of seven New York City public high school mathematics teachers as teachers of mathematics and agents of change. Meeting regularly as a community of practice, the teachers and author/researcher discussed issues of teaching mathematics for social justice; explored activities and lessons around social justice; and created a unit of study that attempted to meet high school level mathematics standards, while addressing a social justice issue affecting the lives of urban students. The author reports on the mathematics teachers, growing awareness of and concerns about …