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Earlier Buddhist Theories Of Free Will: Compatibilism, Rick Repetti

Publications and Research

This is the first part of a three-article series that examines Budd-hist accounts of free will. The present article introduces the issues and reviews earlier attempts by Frances Story, Walpola Rāhula, Luis Gómez, and David Kalupahana. These “early-period” authors advocate compatibilism between Buddhist doctrine, determinism (the doctrine of universal lawful causation), and free will. The second article reviews later attempts by Mark Siderits, Gay Watson, Joseph Goldstein, and Charles Goodman. These “middle-period” authors embrace either partial or full incompatibilism. The third article reviews recent attempts by Nicholas F. Gier and Paul Kjellberg, Asaf Federman, Peter Harvey, and B. Alan Wallace. …

Liquid-Liquid Phase Transition And Glass Transition In A Monoatomic Model System, Limei Xu, Sergey V. Buldyrev, Nicolas Giovambattista, H. Eugene Stanley

Publications and Research

We review our recent study on the polyamorphism of the liquid and glass states in a monatomic system, a two-scale spherical-symmetric Jagla model with both attractive and repulsive interactions. This potential with a parametrization for which crystallization can be avoided and both the glass transition and the liquid-liquid phase transition are clearly separated, displays water-like anomalies as well as polyamorphism in both liquid and glassy states, providing a unique opportunity to study the interplay between the liquid-liquid phase transition and the glass transition. Our study on a simple model may be useful in understanding recent studies of polyamorphism in metallic …

Intradermal Immunization Of Mice With Radiation-Attenuated Sporozoites Of Plasmodium Yoelii Induces Effective Protective Immunity, Tatiana Voza, Chahnaz Kebaier, Jerome P. Vanderberg

Publications and Research

Background Intravenous injection of mice with attenuated Plasmodium berghei sporozoites induces sterile immunity to challenge with viable sporozoites. Non-intravenous routes have been reported to yield poor immunity. Because intravenous immunization has been considered to be unacceptable for large scale vaccination of humans, assessment was made of the results of intradermal immunization of mice with Plasmodium yoelii, a rodent malaria parasite whose infectivity resembles that of human malaria. Methods Mice were immunized with two injections of isolated, radiation-attenuated P. yoelii sporozoites, either by intravenous (IV) or intradermal (ID) inoculation. In an attempt to enhance protective immunogenicity of ID-injections, one group of …

Graphs Of Bounded Degree And The P-Harmonic Boundary, Michael J. Puls

Publications and Research

Let p be a real number greater than one and let G be a connected graph of bounded degree. We introduce the p-harmonic boundary of G and use it to characterize the graphs G for which the constant functions are the only p-harmonic functions on G. We show that any continuous function on the p-harmonic boundary of G can be extended to a function that is p-harmonic on G. We also give some properties of this boundary that are preserved under rough-isometries. Now let Gamma be a finitely generated group. As an application of our results, we characterize the vanishing …

Experiences Of Women Who Have Lost Young Children To Aids In Kwazulu-Natal, South Africa: A Qualitative Study, Craig Demmer

Publications and Research

Background AIDS continues to be the leading cause of death in South Africa. Little is known about the experiences of mothers who have lost a young child to AIDS. The purpose of this qualitative study was to explore the attitudes and experiences of women who had lost a young child to HIV/AIDS in KwaZulu-Natal Province, South Africa.

Methods In-depth interviews were conducted with 10 women who had lost a child to AIDS. The average age of the deceased children was six years. Interviews were also conducted with 12 key informants to obtain their perspectives on working with women who had …

Hybrid Micro-/Nanogels For Optical Sensing And Intracellular Imaging, Weitai Wu, Shuiqin Zhou

Publications and Research

Hybrid micro-/nanogels are playing an increasing important part in a diverse range of applications, due to their tunable dimensions, large surface area, stable interior network structure, and a very short response time. We review recent advances and challenges in the developments of hybrid micro-/nanogels toward applications for optical sensing of pH, temperature, glucose, ions, and other species as well as for intracellular imaging. Due to their unique advantages, hybrid micro-/nanogels as optical probes are attracting substantial interests for continuous monitoring of chemical parameters in complex samples such as blood and bioreactor fluids, in chemical research and industry, and in food …

A Microfluidic Device To Establish Concentration Gradients Using Reagent Density Differences, Qingjun Kong, Richard A. Able, Jr., Veronica Dudu, Maribel Vazquez

Publications and Research

Microfabrication has become widely utilized to generate controlled microenvironments that establish chemical concentration gradients for a variety of engineering and life science applications. To establish microfluidic flow, the majority of existing devices rely upon additional facilities, equipment, and excessive reagent supplies, which together limit device portability as well as constrain device usage to individuals trained in technological disciplines. The current work presents our laboratory-developed bridged microLane system, which is a stand-alone device that runs via conventional pipette loading and can operate for several days without need of external machinery or additional reagent volumes. The bridged microLane is a two-layer polydimethylsiloxane …

Leukocytosis As Prognostic Indicator Of Major Injury, Lorenzo Paladino, Ramanand A. Subramanian, Elisabeth Bonilla, Richard H. Sinert

Publications and Research

Objective To test the diagnostic use of the triage white blood cell (WBC) count in differentiating major from minor injuries. Methods We conducted a retrospective study of a prospectively collected database of trauma patients 13 years of age or older at a Level I trauma center from January 2005 through December 2008. We excluded all patients with obvious life-threatening injuries requiring immediate surgery, isolated head trauma, transferred from another institution or dead on arrival. We recorded age, sex, injury mechanism, vital signs, WBC, base deficit (BD), lactate (LAC) and calculated injury severity scores (ISS). Major injury was defined as either …

Optimizing In Vitro Propagation Of Rosa Persica, Maryam Jafarkhani-Kermani, Pegah Khosravi, Somayeh Kavand

Publications and Research

Rosa persica with a distinctive red eye is a good candidate for addition to the breeding pool of roses. In order to optimize micropropagation of R. persica, three culture media (MS, QL and VS) were compared. The maximum growth rate was observed in the VS medium. Addition of FeEDTA (Fe: 65.4 mg/l), calcium gluconate (Cg: 2.7 g/l) and Gamborg vitamins (B5) instead of VS vitamins, alone or in combinationwith VS medium were compared. The maximum growth rate was obtained in the medium containing VS + Cg + B5 (VSCgB5). Various concentrations of BAP (0, 2, 4 and 8 μM ) …

A Richer And More Diverse Future For Cell Biology, Sandra L. Schmid, Molly Carnes, Ursula Goodenough, Nancy Hopkins, Phoebe Leboy, Sandra Masur, Virginia Valian

Publications and Research

No abstract provided.

Sex Partnerships, Health, And Social Risks Of Young Men Leaving Jail: Analyzing Data From A Randomized Controlled Trial, Megha Ramaswamy, Nicholas Freudenberg

Publications and Research

Background Young men involved in the criminal justice system face disproportionately high rates of sexual risk behavior, drug, use, and violence. Little is known about how their involvement in sex partnerships might mitigate their unique health and social risks. This study explores whether sex partner experience protects against harmful sexual behaviors, drug problems, violence, and recidivism in 16-18-year-old Black and Latino men leaving a US jail. Methods Data were drawn from the Returning Educated African-American and Latino Men to Enriched Neighborhoods (REAL MEN) study conducted between 2003-2007, which tracked 552 adolescents during their time in a New York City jail …

Building Capacity For Public And Population Health Research In Africa: The Consortium For Advanced Research Training In Africa (Carta) Model, Alex C. Ezeh, Chimaraoke O. Izugbara, Caroline W. Kabiru, Sharon Fonn, Kathleen Kahn, Lenore Manderson, Akinyinka Omigbodun, Margaret Thorogood, Ashiwel S. Undieh

Publications and Research

Background: Globally, sub-Saharan Africa bears the greatest burden of disease. Strengthened research capacity to understand the social determinants of health among different African populations is key to addressing the drivers of poor health and developing interventions to improve health outcomes and health systems in the region. Yet, the continent clearly lacks centers of research excellence that can generate a strong evidence base to address the region’s socio-economic and health problems. Objective and program overview: We describe the recently launched Consortium for Advanced Research Training in Africa (CARTA), which brings together a network of nine academic and four research institutions from …

U.S. Multinationals In A World Of Uncertainty, Peter M. Robinson

Publications and Research

In this paper, Peter Robinson, president of the U.S. Council for International Business, provides his perspective on the challenges U.S. multinationals faced in the aftermath of the global financial crisis of 2007–2008, considered by many economists to have been the worst financial crisis since the Great Depression of the 1930s. As the American affiliate of the leading international business organizations, including the International Chamber of Commerce, the International Organization of Employers, and the Business and Industry Advisory Committee to the OECD, the USCIB provides business views to policy makers and regulatory authorities worldwide.

Ealles Englalandes Cyningc: Cnut's Territorial Kingship And Wulfstan's Paronomastic Play, Paul Gates

Publications and Research

The phrase ealles Englalandes cyningc appears for the first time in I–II Cnut, and represents a shift in the discourse of Anglo-Saxon kingship, changing it from king over a people to king over a territory, redefining the discourse of nationhood.

Overcoming The Model Minority Myth: Experiences Of Filipino American Graduate Students, Kevin L. Nadal, Stephanie T. Pituc, Marc P. Johnston, Theresa Esparrago

Publications and Research

Filipino Americans are one of the largest immigrant groups in the United States and the second largest Asian American/Pacific Islander ethnic group. However, there is little research focusing on the unique experiences of this group, particularly in higher education. This paper presents a qualitative exploration of the experiences of Filipino American graduate students utilizing consensual qualitative research methodology. Results were categorized into domains and themes, with an example of a domain being "deficiencies and lack of resources" and an example of a theme being "Filipino Americans as different from Asian Americans." Implications for higher education administrators and researchers are discussed.

Tensorial Reconstruction At The Integrand Level, G. Heinrich, Giovanni Ossola, T. Reiter, F. Tramontano

Publications and Research

We present a new approach to the reduction of one-loop amplitudes obtained by reconstructing the tensorial expression of the scattering amplitudes. The reconstruction is performed at the integrand level by means of a sampling in the integration momentum. There are several interesting applications of this novel method within existing techniques for the reduction of one-loop multi-leg amplitudes: to deal with numerically unstable points, such as in the vicinity of a vanishing Gram determinant; to allow for a sampling of the numerator function based on real values of the integration momentum; to optimize the numerical reduction in the case of long …

The Role Of Accounting In The Financial Crisis: Lessons For The Future, S.P. Kothari

Publications and Research

No abstract provided.

The Geography Of Black Candidate Electoral Success, Marcus Allen, Marvin King

Publications and Research

In this manuscript, we reexamine claims about the geography of electoral success of African American candidates. Barack Obama's historic election in 2008 prompted journalists, partisans, and scholars to review prior notions of where African American candidates can successfully contend for elected office. Although Obama's victory is just an anecdotal national example (albeit an important one), we review the available evidence at the state level to understand what factors might impede African American electoral success. Heretofore, the literature focused on the density of the black population, and the interconnectedness of region and white racial attitudes. This paper shows that these old …

Editor’S Farewell, Irvin Sam Schonfeld

Publications and Research

No abstract provided.

Mothers In Trouble: Coping With Actual Or Pending Separation From Children Due To Incarceration, Katarzyna Celinska, Jane A. Siegel

Publications and Research

Although female offenders are the fastest growing population in prison today, relatively few studies focus on their unique experiences as mothers. In this study, the authors utilize 74 semistructured interviews with mothers before trial and during incarceration to document coping strategies employed to deal with potential or actual separation from their children. From the study data, seven strategies emerge: being a good mother, mothering from prison, role redefinition, disassociation from prisoner identity, self-transformation, planning and preparation, and self-blame. The findings show that mothers used multiple strategies and tended to employ emotion-focused and adaptive coping techniques. The policy implications are discussed.

The Trouble With Archie: Locating And Accessing Primary Sources For The Study Of The 1970s Us Sitcom, All In The Family, Kathleen Collins

Publications and Research

The US television sitcom, All in the Family was groundbreaking in its social relevance with regard to contemporary issues of race, class, gender, sexual orientation and politics, among others. The interest in All in the Family continues into the 21st century, and television historians and fans continue to seek out elusive historical video of the show. The author addresses the challenges in discovering, locating and accessing primary source visual material for its study and speculates on the future of accessibility of historical broadcasts, the impact on television studies and potential solutions. Reprinted by permission of the publisher.

Forecasting The New York State Economy With “Terraced” Vars And Coincident Indices, Eric Doviak, Sean P. Macdonald

Publications and Research

This paper introduces “Terraced” Vector Autoregressive (VAR) models, an innovative twist on traditional VAR modeling, which allows the econometrician to simultaneously forecast both exogenous and endogenous variables and the confidence intervals around those forecasts. In an application of our Terraced VAR framework, we have estimated coincident indices of economic activity for the United States, New York State and the six largest metropolitan areas of New York State and incorporated them into Terraced VARs, which forecast the unemployment rate, total non-farm employment, real wages and average hours worked in manufacturing in those regions.

Identification Of An Archaeal Presenilin-Like Intramembrane Protease, Celia Torres-Arancivia, Carolyn M. Ross, Jose Chavez, Zahra Assur, Georgia Dolios, Filippo Mancia, Iban Ubarretxena-Belandia

Publications and Research

Background: The GXGD-type diaspartyl intramembrane protease, presenilin, constitutes the catalytic core of the c-secretase multi-protein complex responsible for activating critical signaling cascades during development and for the production of b-amyloid peptides (Ab) implicated in Alzheimer’s disease. The only other known GXGD-type diaspartyl intramembrane proteases are the eukaryotic signal peptide peptidases (SPPs). The presence of presenilin-like enzymes outside eukaryots has not been demonstrated. Here we report the existence of presenilin-like GXGD-type diaspartyl intramembrane proteases in archaea.

Methodology and Principal Findings: We have employed in vitro activity assays to show that MCMJR1, a polytopic membrane protein from the archaeon Methanoculleus marisnigri JR1, …

Dmyc Functions Downstream Of Yorkie To Promote The Supercompetitive Behavior Of Hippo Pathway Mutant Cells, Marcello Ziosi, Luis Alberto Baena-López, Daniela Grifoni, Francesca Froldi, Andrea Pession, Flavio Garoia, Vincenzo Trotta, Paola Bellosta, Sandro Cavicchi, Annalisa Pession

Publications and Research

Genetic analyses in Drosophila epithelia have suggested that the phenomenon of “cell competition” could participate in organ homeostasis. It has been speculated that competition between different cell populations within a growing organ might play a role as either tumor promoter or tumor suppressor, depending on the cellular context. The evolutionarily conserved Hippo (Hpo) signaling pathway regulates organ size and prevents hyperplastic disease from flies to humans by restricting the activity of the transcriptional cofactor Yorkie (yki). Recent data indicate also that mutations in several Hpo pathway members provide cells with a competitive advantage by unknown mechanisms. Here we provide insight …

The Terebridae And Teretoxins: Combining Phylogeny And Anatomy For Concerted Discovery Of Bioactive Compounds, Nicolas Puillandre, Mandë Holford

Publications and Research

The Conoidea superfamily, comprised of cone snails, terebrids, and turrids, is an exceptionally promising group for the discovery of natural peptide toxins. The potential of conoidean toxins has been realized with the distribution of the first Conus (cone snail) drug, Prialt (ziconotide), an analgesic used to alleviate chronic pain in HIV and cancer patients. Cone snail toxins (conotoxins) are highly variable, a consequence of a high mutation rate associated to duplication events and positive selection. As Conus and terebrids diverged in the early Paleocene, the toxins from terebrids (teretoxins) may demonstrate highly divergent and unique functionalities. Recent analyses of the …

Dipolar Cortico-Muscular Electrical Stimulation: A Novel Method That Enhances Motor Function In Both - Normal And Spinal Cord Injured Mice, Zaghloul Ahmed

Publications and Research

Background Electrical stimulation of the central and peripheral nervous systems is a common tool that is used to improve functional recovery after neuronal injury. Methods Here we described a new configuration of electrical stimulation as it was tested in anesthetized control and spinal cord injury (SCI) mice. Constant voltage output was delivered through two electrodes. While the negative voltage output (ranging from -1.8 to -2.6 V) was delivered to the muscle via transverse wire electrodes (diameter, 500 μm) located at opposite ends of the muscle, the positive output (ranging from + 2.4 to +3.2 V) was delivered to the primary …

Negative Effects Of Paternal Age On Children's Neurocognitive Outcomes Can Be Explained By Maternal Education And Number Of Siblings, Ryan D. Edwards, Jennifer Roff

Publications and Research

Background Recent findings suggest advanced paternal age may be associated with impaired child outcomes, in particular, neurocognitive skills. Such patterns are worrisome given relatively universal trends in advanced countries toward delayed nuptiality and fertility. But nature and nurture are both important for child outcomes, and it is important to control for both when drawing inferences about either pathway.

Methods and Findings We examined cross-sectional patterns in six developmental outcome measures among children in the U.S. Collaborative Perinatal Project (n=31,346). Many of these outcomes at 8 mo, 4 y, and 7 y of age (Bayley scales, Stanford Binet Intelligence Scale, Graham-Ernhart …

Alternation Rate In Perceptual Bistability Is Maximal At And Symmetric Around Equi-Dominance, Rubén Moreno-Bote, Asya Shpiro, John Rinzel, Nava Rubin

Publications and Research

When an ambiguous stimulus is viewed for a prolonged time, perception alternates between the different possible interpretations of the stimulus. The alternations seem haphazard, but closer inspection of their dynamics reveals systematic properties in many bistable phenomena. Parametric manipulations result in gradual changes in the fraction of time a given interpretation dominates perception, often over the entire possible range of zero to one. The mean dominance durations of the competing interpretations can also vary over wide ranges (from less than a second to dozens of seconds or more), but finding systematic relations in how they vary has proven difficult. Following …

The Uneven Distribution Of Social Suffering: Documenting The Social Health Consequences Of Neo-Liberal Social Policy On Marginalized Youth, Michelle Fine, Brett G. Stoudt, Maddy Fox, Maybelline Santos

Publications and Research

In 2009, British epidemiologists Richard Wilkinson and Kate Pickett published "The Spirit Level: Why Greater Equality Makes Societies Strong", in which they argue that severely unequal societies produce high rates of ‘social pain”: adverse outcomes including school drop out, teen pregnancy, mental health problems, lack of social trust, high mortality rates, violence and crime, low social participation. Their volume challenges the belief that the extent of poverty in a community predicts negative outcomes. They assert instead that the size of the inequality gap defines the material and psychological contours of the chasm between the wealthiest and the most impoverished, enabling …

Management Of Online Tutorials: A Model For A Step-By-Step Approach, Kanu A. Nagra, Dorothea J. Coiffe

Publications and Research

Online tutorials have great potential to reach a large population and to accommodate multiple learning styles anytime and anywhere. This paper describes the management of online tutorials and related concepts in detail. The review of literature method is used to study the variables. The variables under study include the mission, objectives, funding, manpower, in-house creation, outsourcing, incorporation in curriculum, content, type, technology, metadata, discovery services, script design, standards, assessment, professional training, marketing techniques and future goals for creation and management of online tutorials in libraries. A practical model based on literature study and the authors' experience with online tutorials is …