Digital Commons Network^™

The Magnetic Couples Study: Protocol For A Mixed Methods Prospective Cohort Study Of Hiv-Serodifferent Heterosexual Couples’ Perspectives And Use Of Pre-Exposure Prophylaxis (Prep), James M. Mcmahon, Janie Simmons, Jessica E. Haberer, Sharon Mannheimer, Natalie M. Leblanc, Leilani Torres, Robert Quiles, Guillermo Aedo, Anabel Javier, Amy Braksmajer, Graham Harriman, Nicole Trabold, Enrique R. Pouget, Ann Kurth, Martez D. R Smith, Judith Brasch, Eric J. Podsiadly, Peter L. Anderson

Publications and Research

Introduction HIV transmission within serodifferent heterosexual couples plays a key role in sustaining the global HIV pandemic. In the USA, transmission within established mixed-status couples accounts for up to half of all new HIV infections among heterosexuals. Oral HIV pre-exposure prophylaxis (PrEP) is a highly effective prevention method, although underutilised among serodifferent couples. Moreover, there is a dearth of research on US HIV-serodifferent couples’ perspectives and use of PrEP, alone or in combination with other prevention methods. In this paper, we describe the study protocol for the Magnetic Couples Study, designed to fill critical knowledge gaps regarding HIV-serodifferent heterosexual couples’ …

Mother Monsters And Monster Mothers From Dracula To Stranger Things, Melissa Dinsman

Publications and Research

Netflix’s hit show Stranger Things is an homage to 1970s and 1980s sci-fi and horror, including Alien and Aliens, Carrie, the Star Wars trilogy, and Poltergeist, as well as buddy adventure films like Goonies and Stand by Me. But it is also, in its obsessive presentation of monsters as mothers and mothers as monsters, a show that takes its 1980s mothering cues straight out of Bram Stoker’s 1890s. Despite its 2016 production date, the Duffer Brother’s Stranger Things presents viewers with very old fashioned ideas of mothering, with Joyce Byers (Wynona Ryder) as the single, but exceedingly pro-active mom from …

Public Knowledge, Emily Drabinski

Publications and Research

An editorial framing the author's perspective on book reviews as a form of scholarly communication.

Implementing Excellence In Diversity, Equity, And Inclusion In The Library Workforce: Tips To Overcome Challenges, Kanu A. Nagra, Bernadette M. López-Fitzsimmons

Publications and Research

Diversifying the library workforce is challenging, with the graduation data of library and information science degrees not representing equity in demographics for diverse populations. Is this the reason for the lack of diversity among library staff or are recruitment practices not based on measurable performance standards? Both questions call upon the library and information science (LIS) profession to address diverse staffing issues to remedy these challenges.

The Cost Of Being Black In Social Work Practicum, Nia Johnson, Paul Archibald, Anthony Estreet, Amanda Morgan

Publications and Research

The social work profession is not exempt from fueling institutional racism, which affects the provision of social work practicum education for Black social work students. This article highlights how the historical and current social cost of being Black in the United States presents itself within social work education’s signature pedagogy. Social workers who hold bachelor’s degrees in social work (BSW) are more likely to be Black than those holding master’s degrees in social work (MSW; Salsberg et al., 2017). It takes Black students longer to earn an MSW degree though they are more likely to hold a BSW while also …

Radical Interrelated Qualitative Space In The Midst Of Multipandemics: A Collaborative Scholarly Personal Narrative, Lisa Delacruz Combs, Maretha Maretha Dellarosa, Myung-Jin Kim, Alexander G-J Pittman, Chelsea Chelsea Gilbert, Spencer J. Smith, Tessa Tessa Smith, Shay N. Valley, Penny A. Pasque

Publications and Research

Given the current unprecedented multiple pandemics of COVID-19, anti-Black and anti-Asian violence, and white supremacy, we—a group of graduate students and a faculty member who hold diverse identities across disciplines, race, gender, nationality, and additional categories—came together to focus on qualitative research as an ontological, epistemological, and axiological space toward community and culture change. Specifically, we took up scholarly personal narrative, which centers postmodernism and focuses on the reality that “we see what we believe; we observe what we narrate; we transform what we reframe. ”What emerged were radical interrelated understandings of privilege, guilt, and the importance of kinship. As …

Part Iii: Chemical Exposure From Manufactured Gas Plants: Naphthalene?, Aneeza Hussain

Publications and Research

In the previous parts of this research, we studied the historical, sociological, and public policy impact of the former manufactured gas plant site at Gowanus. Gowanus Canal is heavily contaminated with coal tar and was found to be a concern of public health risk from chemical exposure to naphthalene, benzene, toluene, ethylbenzene, and xylene pollutants on former Manufactured Gas Plant (MGP) sites when developed. We studied all these chemicals and their risks to the public around the site. We concluded that Naphthalene is a toxic chemical and has carcinogenic properties. In the present study, with an emphasis on the Chemistry …

Direct Observation Of Chaotic Resonances In Optical Microcavities, Shuai Wang, Shuai Liu, Yilin Liu, Shumin Xiao, Zi Wang, Yubin Fan, Jiecai Han, Li Ge, Qinghai Song

Publications and Research

Optical microcavities play a significant role in the study of classical and quantum chaos. To date, most experimental explorations of their internal wave dynamics have focused on the properties of their inputs and outputs, without directly interrogating the dynamics and the associated mode patterns inside. As a result, this key information is rarely retrieved with certainty, which significantly restricts the verification and understanding of the actual chaotic motion. Here we demonstrate a simple and robust approach to directly and rapidly map the internal mode patterns in chaotic microcavities. By introducing a local index perturbation through a pump laser, we report …

Telomeric And Sub-Telomeric Structure And Implications In Fungal Opportunistic Pathogens, Raffaella Diotti, Michelle Esposito, Chang Hui Shen

Publications and Research

Telomeres are long non-coding regions found at the ends of eukaryotic linear chromosomes. Although they have traditionally been associated with the protection of linear DNA ends to avoid gene losses during each round of DNA replication, recent studies have demonstrated that the role of these sequences and their adjacent regions go beyond just protecting chromosomal ends. Regions nearby to telomeric sequences have now been identified as having increased variability in the form of duplications and rearrangements that result in new functional abilities and biodiversity. Furthermore, unique fungal telomeric and chromatin structures have now extended clinical capabilities and understanding of pathogenicity …

A Fused Radar–Optical Approach For Mapping Wetlands And Deepwaters Of The Mid–Atlantic And Gulf Coast Regions Of The United States, Brian T. Lamb, Maria A. Tzortziou, Kyle C. Mcdonald

Publications and Research

Tidal wetlands are critically important ecosystems that provide ecosystem services including carbon sequestration, storm surge mitigation, water filtration, and wildlife habitat provision while supporting high levels of biodiversity. Despite their importance, monitoring these systems over large scales remains challenging due to difficulties in obtaining extensive up-to-date ground surveys and the need for high spatial and temporal resolution satellite imagery for effective space-borne monitoring. In this study, we developed methodologies to advance the monitoring of tidal marshes and adjacent deepwaters in the Mid-Atlantic and Gulf Coast United States. We combined Sentinel-1 SAR and Landsat 8 optical imagery to classify marshes and …

Evaluation Of Log P, Pka, And Log D Predictions From The Sampl7 Blind Challenge, Teresa Danielle Bergazin, Nicolas Tielker, Yingying Zhang, Junjun Mao, M. R. Gunner, Karol Francisco, Carlo Ballatore, Stefan M. Kast, David L. Mobley

Publications and Research

The Statistical Assessment of Modeling of Proteins and Ligands (SAMPL) challenges focuses the computational modeling community on areas in need of improvement for rational drug design. The SAMPL7 physical property challenge dealt with prediction of octanol-water partition coefficients and pK_a for 22 compounds. The dataset was composed of a series of N-acylsulfonamides and related bioisosteres. 17 research groups participated in the log P challenge, submitting 33 blind submissions total. For the pK_a challenge, 7 different groups participated, submitting 9 blind submissions in total. Overall, the accuracy of octanol-water log P predictions in the SAMPL7 challenge was …

The Effect Of Fluid Flow Shear Stress And Substrate Stiffness On Yes-Associated Protein (Yap) Activity And Osteogenesis In Murine Osteosarcoma Cells, Thomas R. Coughlin, Ali Sana, Kevin Voss, Abhilash Gadi, Upal Basu-Roy, Caroline M. Curtin, Alka Mansukhani, Oran D. Kennedy

Publications and Research

Osteosarcoma (OS) is an aggressive bone cancer originating in the mesenchymal lineage. Prognosis for metastatic disease is poor, with a mortality rate of approximately 40%; OS is an aggressive disease for which new treatments are needed. All bone cells are sensitive to their mechanical/ physical surroundings and changes in these surroundings can affect their behavior. However, it is not well understood how OS cells specifically respond to fluid movement, or substrate stiffness—two stimuli of relevance in the tumor microenvironment. We used cells from spontaneous OS tumors in a mouse engineered to have a bone-specific knockout of pRb-1 and p53 in …

Area Characteristics And Consumer Nutrition Environments In Restaurants: An Examination Of Hispanic Caribbean Restaurants In New York City, Melissa Fuster, Hanish Kodali, Krishnendu Ray, Brian Elbel, Margaret A. Handley, Terry T. Huang, Glen Johnson

Publications and Research

Hispanics in the USA, particularly those of Caribbean descent, experience high levels of diet-related diseases and dietary risk factors. Restaurants are an increasingly important yet understudied source of food and may present opportunities to positively influence urban food environments. We sought to explore food environments further, by examining the association between neighborhood characteristics and restaurant consumer nutrition environments within New York City’s Hispanic Caribbean (HC) restaurant environments. We applied an adapted version of the Nutrition Environment Measurements Survey for Restaurants (NEMS-R) to evaluate a random sample of HC restaurants (n=89). NEMS-HCR scores (continuous and categorized as low, medium, and high …

Quantifying The Speed Of Chromatophore Activity At The Single-Organ Level In Response To A Visual Startle Stimulus In Living, Intact Squid, Stavros P. Hadjisolomou, Rita W. El-Haddad, Kamil Kloskowski, Alla Chavarga, Israel Abramov

Publications and Research

The speed of adaptive body patterning in coleoid cephalopods is unmatched in the natural world. While the literature frequently reports their remarkable ability to change coloration significantly faster than other species, there is limited research on the temporal dynamics of rapid chromatophore coordination underlying body patterning in living, intact animals. In this exploratory pilot study, we aimed to measure chromatophore activity in response to a light flash stimulus in seven squid, Doryteuthis pealeii. We video-recorded the head/arms, mantle, and fin when squid were presented with a light flash startle stimulus. Individual chromatophores were detected and tracked over time using image …

Remission Of Type 2 Diabetes With Very Low-Calorie Diets —A Narrative Review, Susan Juray, Kathleen V. Axen, Steven Trasino

Publications and Research

Very low-calorie diets (VLCD) are hypocaloric dietary regimens of approximately 400–800 kcal/day that result in 20–30% reductions in body weight, sometimes in just 12–16 weeks. A body of evidence demonstrates that adherence to VLCD in adults with type 2 diabetes (T2D) can result in marked improvements to glycemic control and even full T2D remission, challenging the convention that T2D is a lifelong disease. Although these data are promising, the majority of VLCD studies have focused on weight loss and not T2D remission as a primary endpoint. Moreover, there is a wide range of VLCD protocols and definitions of T2D remission …

Protein Motifs For Proton Transfers That Build The Transmembrane Proton Gradient, Divya Kaur, Umesh Khaniya, Yingying Zhang, M. R. Gunner

Publications and Research

Biological membranes are barriers to polar molecules, so membrane embedded proteins control the transfers between cellular compartments. Protein controlled transport moves substrates and activates cellular signaling cascades. In addition, the electrochemical gradient across mitochondrial, bacterial and chloroplast membranes, is a key source of stored cellular energy. This is generated by electron, proton and ion transfers through proteins. The gradient is used to fuel ATP synthesis and to drive active transport. Here the mechanisms by which protons move into the buried active sites of Photosystem II (PSII), bacterial RCs (bRCs) and through the proton pumps, Bacteriorhodopsin (bR), Complex I and Cytochrome …

Covid-19 Multi-Targeted Drug Repurposing Using Few-Shot Learning, Yang Liu, You Wu, Xiaoke Shen, Lei Xie

Publications and Research

The life-threatening disease COVID-19 has inspired significant efforts to discover novel therapeutic agents through repurposing of existing drugs. Although multi-targeted (polypharmacological) therapies are recognized as the most efficient approach to system diseases such as COVID-19, computational multi-targeted compound screening has been limited by the scarcity of high-quality experimental data and difficulties in extracting information from molecules. This study introduces MolGNN , a new deep learning model for molecular property prediction. MolGNN applies a graph neural network to computational learning of chemical molecule embedding. Comparing to state-of-the-art approaches heavily relying on labeled experimental data, our method achieves equivalent or superior prediction …

Fostering Information Literacy: A Call For Collaboration Between Academic Librarians And Msw Instructors., Sarah C. Johnson, Margaret Bausman, Sarah Ward

Publications and Research

Genuine collaboration between academic librarians and social work faculty in which information literacy is embedded in social work education is lacking. Drawing from the results of the authors’ 2016 quantitative study surveying academic social work librarians across the United States, this qualitative follow-up uses data from 27 semi-structured interviews concerning the prevalence and nature of information literacy instruction (ILI) in social work education, how ILI is introduced and sustained in social work curricula, and the alignment between ILI efforts with institutional goals, guidelines from accreditation authorities, and professional social work practice standards. The literature review engages the reader in a …

Measuring Procedural Justice Policy Adherence During Use Of Force Events: The Body-Worn Camera As A Performance Monitoring Tool, Victoria A. Sytsma, Eric L. Piza, Vijay F. Chillar, Leigh S. Grossman

Publications and Research

This study capitalizes on a successful researcher–practitioner partnership to conduct a systematic social observation (SSO) of police body-worn camera (BWC) footage in Newark, NJ. To demonstrate the utility of BWCs as performance monitoring tools, we measure officer adherence to procedural justice standards throughout use of force events as mandated in the Newark Police Division’s updated policies pursuant to an ongoing federal consent decree. Overall, a slim majority of use of force events are procedurally just. However, results indicate several instances of policy noncompliance. Results are discussed, and policy recommendations related to procedural justice policy violations and BWCs for performance monitoring …

Admissions Of Covid-Positive Patients To Us Nursing Homes With Personal Protective Equipment Or Staffing Shortages, Diane M. Gibson, Jessica Greene

Publications and Research

Background: US nursing homes are required to follow Centers for Disease Control guidance for COVID-19 transmission-based precautions (TBP) when admitting COVID-positive patients.

Objective: To assess how frequently nursing homes had shortages of personal protective equipment (PPE) or staffing in weeks when they admitted COVID-positive patients, which likely made it more difficult to follow TBP, and to compare facility characteristics by admissions practices.

Design and Setting: Facility-level data from the Nursing Home COVID-19 Public File for the period between June 7, 2020 and March 7, 2021 was combined with additional data. The percentages of nursing homes that admitted COVID-positive patients and …

Defining The Basis Of Cyanine Phototruncation Enables A New Approach To Single-Molecule Localization Microscopy, Siddharth S. Matikonda, Dominic A. Helmerich, Mara Meub, Gerti Beliu, Philip Kollmannsberger, Alexander Greer, Markus Sauer, Martin J. Schnermann

Publications and Research

The light-promoted conversion of extensively used cyanine dyes to blue-shifted emissive products has been observed in various contexts. However, both the underlying mechanism and the species involved in this photoconversion reaction have remained elusive. Here we report that irradiation of heptamethine cyanines provides pentamethine cyanines, which, in turn, are photoconverted to trimethine cyanines. We detail an examination of the mechanism and substrate scope of this remarkable twocarbon phototruncation reaction. Supported by computational analysis, we propose that this reaction involves a singlet oxygeninitiated multistep sequence involving a key hydroperoxycyclobutanol intermediate. Building on this mechanistic framework, we identify conditions to improve the …

Detection Methods And Clinical Applications Of Circulating Tumor Cells In Breast Cancer, Hongyi Zhang, Xiaoyan Lin, Yuan Huang, Minghong Wang, Chunmei Cen, Shasha Tang, Marcia R. Dique, Lu Cai, Manuel A. Luis, Jillian Smollar, Yuan Wan, Fengfeng Cai

Publications and Research

Circulating Tumor Cells (CTCs) are cancer cells that split away from the primary tumor and appear in the circulatory system as singular units or clusters, which was first reported by Dr. Thomas Ashworth in 1869. CTCs migrate and implantation occurs at a new site, in a process commonly known as tumor metastasis. In the case of breast cancer, the tumor cells often migrate into locations such as the lungs, brain, and bones, even during the early stages, and this is a notable characteristic of breast cancer. Survival rates have increased significantly over the past few decades because of progress made …

Instructional Design With The Ice Approach In Academic Libraries: A Framework That Integrates Assessing, Learning, And Teaching, Junli Diao

Publications and Research

One-shot instruction in academic libraries is a librarian-controlled bibliographic instruction that responds to the point of information need for subject-related courses. The assessment of teaching effectiveness tends to take a summative approach, which provides an answer to what students learned but does not address how they learned. This column theoretically explores the framework of Ideas-Connections-Extensions (ICE) in library instruction and the classroom setting, which demonstrates learning outcomes and explores the learning journey, and integrates assessment, learning, and teaching through collaborative efforts by academic librarians and classroom faculty.

Depression, Depression Literacy, And Sociodemographic Characteristics Of Korean Americans: A Preliminary Investigation, Kunsook Bernstein, Young-Me Lee, Philmon N. Gona, Shinhi Han, Soonsik Kim, Sun S. Kim

Publications and Research

Despite the rapid growth in the number of Korean Americans (KAs) and the alarmingly high prevalence of depression in this population, relatively little is known about the impact of depression literacy on KAs’ depression. This study investigated the prevalence of depressive symptoms among a community-based sample of KA adults; the associations among socio-demographic characteristics, depression literacy, and depressive symptoms; and predictors related to depressive symptoms. A sample of 600 KAs completed depression and depression literacy scales, as well as socio-demographic questionnaires. Data analyses were conducted to assess the association between depressive symptoms, depression literacy, and the covariates. Forty-five percent of …

Correlates Of Exam Performance In An Introductory Statistics Course: Basic Math Skills Along With Self- Reported Psychological/Behavioral And Demographic Variables, Laura A. Rabin, Anjali Krishnan, Rose Bergdoll, Joshua Fogel

Publications and Research

This study investigated whether basic mathematics skills are associated with undergraduate psychology statistics course performance while simultaneously considering self-reported psychological/behavioral and demographic variables. Participants (n = 460) completed a Math Assessment for College Students (MACS), which included questions ranging from calculating percentages to graphical interpretation. The researchers used a discriminant correspondence analysis to reveal differences in course performance evaluated as the average of three exam grades. For the variation in the average exam scores accounted for by our model, the MACS scores provided the largest contribution. Other variables associated with better exam grades included white ethnicity, non-transfer status, lower year …

Getting To Work: Information Literacy Instruction, Career Courses, And Digitally Proficient Students, Alexandra Hamlett

Publications and Research

This article discusses how following graduation, students often enter the job market unprepared to find, evaluate, and use information in the digital environment effectively. Essentially, there is a disparity between the skills students attain in college coursework, including information literacy (IL) skills, and those required in the workplace, which impacts graduates’ success as new members of the labour market. The article highlights how collaboration between a librarian and an instructor of a career centered course influenced instructional design for IL instruction in their courses. Librarians and instructors will benefit from practical examples from Guttman Community College’s innovative IL Program and …

Contamine De Latour, Gimnopedista Desconegut, Antoni Pizà

Publications and Research

Posats a triar quina de les excentricitats d’Erik Satie és la més simpàtica, la més memorable i la que, al cap i a la fi, resumeix les paradoxes de la seva essència com a artista, jo em quedaria amb la llegenda de la seva dieta. «Jo no menjo més que aliments blancs: ous, sucre, cocos...». D’extravagàncies, però, no en falten en la seva biografia, començant per la gran majoria de les seves composicions a on, no hi trobem com a títols ni «sonates» ni «simfonies», sinó «Embrions dissecats» o «Peces en forma de pera».

Virtual Reference Amid Covid-19 Campus Closure: A Case Study And Assessment, Maureen Garvey

Publications and Research

Purpose – This case study was conducted to assess and make changes to the consortial virtual reference service for the remainder of the period of fully virtual reference (campus closure); a second objective was to consider implications for service design and delivery upon the eventual return to the physical campus.

Design/methodology/approach – This paper begins by introducing the institution, reference practices prior to the pandemic and the changes to reference service necessitated by the campus closure. After a literature review of material related to reference and the pandemic, several years of virtual reference service data are analyzed.

Findings – The …

Turning Collective Digital Stories Of The First-Year Transition To College Into A Web Of Belonging, Mery Diaz, Sandra Cheng, Karen Goodlad, Jennifer Sears, Phil Kreniske, Ashwin Satyanarayana

Publications and Research

In this article, we present lessons learned from "Our Stories," a digital writing project designed to assist students in the transition from high school to college. From the collective digital narratives of first-year and first-generation students at an urban public college, who are primarily Black, Indigenous, and People of Color (BIPOC), low-income, and immigrant, and who participated in a First-year Learning Communities course, we examine the challenges of becoming a college student at a public college. Further, we explore how digital writing supports community-building and influences students' transition experience, in particular, making sense of shared challenges. For these BIPOC students, …

Relationships Between Sports, Physical Activity Participation, And Phys-Ed Gpa: Results And Analyses From A National Sample Of Asian American Students, Howard Z. Zeng, Raymond E. Weston, Juan Battle

Publications and Research

Relationships among sports, physical activity (PA) participation, and educational outcomes have been studied in various venues, however, used a longitudinal method with a national sample of Asian-American High-School Students (AAHSS) was barely covered. This study employed the latest National High-School Longitudinal Study data (Participants, N = 950); hierarchical regression modeling and intersectionality theory examined, analyzed, and evaluated the relationships among sports, PA participation, and the outcomes on the physical education grade point average (Phys-Ed GPA). Moreover, the demographics factors impact on the participants' Phys-Ed GPA was also analyzed and evaluated. The primary results included: 1) the female students who participate …