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Accumulation Of Unacetylatable Snf2p At The Ino1 Promoter Is Detrimental To Remodeler Recycling Supply For Cup1 Induction, Michelle Esposito, Goldie Libby Sherr, Anthony Esposito, George Kaluski, Farris Ellington, Chang-Hui Shen Mar 2020

Accumulation Of Unacetylatable Snf2p At The Ino1 Promoter Is Detrimental To Remodeler Recycling Supply For Cup1 Induction, Michelle Esposito, Goldie Libby Sherr, Anthony Esposito, George Kaluski, Farris Ellington, Chang-Hui Shen

Publications and Research

Chromatin structure plays a decisive role in gene regulation through the actions of transcriptional activators, coactivators, and epigenetic machinery. These trans-acting factors contribute to gene expression through their interactions with chromatin structure. In yeast INO1 activation, transcriptional activators and coactivators have been defined through intense study but the mechanistic links within these trans-acting factors and their functional implications are not yet fully understood. In this study, we examined the crosstalk within transcriptional coactivators with regard to the implications of Snf2p acetylation during INO1 activation. Through various biochemical analysis, we demonstrated that both Snf2p and Ino80p chromatin remodelers accumulate …


Understanding The Dimensions Of Medical Crowdfunding: A Visual Analytics Approach, Jie Ren, Viju Raghupathi, Wullianallur Raghupathi Mar 2020

Understanding The Dimensions Of Medical Crowdfunding: A Visual Analytics Approach, Jie Ren, Viju Raghupathi, Wullianallur Raghupathi

Publications and Research

Background: Medical crowdfunding has emerged as a growing field for fundraising opportunities. Some environmental trends have driven the emergence of campaigns to raise funds for medical care. These trends include lack of medical insurance, economic backlash following the 2008 financial collapse, and shortcomings of health care regulations.

Objective: Research regarding crowdfunding campaign use, reasons, and effects on the provision of medical care and individual relationships in health systems is limited. This study aimed to explore the nature and dimensions of the phenomenon of medical crowdfunding using a visual analytics approach and data crawled from the GoFundMe crowdfunding platform in 2019. …


Collection Development At Two Armenian University Libraries: A Conversation With Librarians And Faculty, John Carey, D. Aram Donabedian, Arshak Balayan Mar 2020

Collection Development At Two Armenian University Libraries: A Conversation With Librarians And Faculty, John Carey, D. Aram Donabedian, Arshak Balayan

Publications and Research

In the summer of 2016 two Hunter College librarians, working with a colleague in the Republic of Armenia, conducted an IRB-approved focus group at the American University of Armenia in Yerevan, Armenia. This group drew participants from the libraries and other academic departments of the American University of Armenia as well as Yerevan State University, a large public institution. The discussion attempted to ascertain whether these libraries have devised effective strategies to acquire materials and build collections in the face of the challenges they face (budgetary, linguistic, and sometimes political) and whether faculty at these institutions feel their library’s collection …


Lamin Fofana: Blues, Alaina Claire Feldman, Dino Dincer Sirin, Lamin Fofana Mar 2020

Lamin Fofana: Blues, Alaina Claire Feldman, Dino Dincer Sirin, Lamin Fofana

Publications and Research

Catalogue for the exhibition "Lamin Fofana: Blues" presented at Baruch College's Mishkin Gallery in 2020.


Paleopathological Research In Continental China: Introduction To The Special Section, Elizabeth Berger, Kate Pechenkina Mar 2020

Paleopathological Research In Continental China: Introduction To The Special Section, Elizabeth Berger, Kate Pechenkina

Publications and Research

We set out to assemble this special issue of IJPP with three goals in mind: (1) to familiarize Anglophone readers with research on paleopathology conducted by Chinese scholars; (2) to enhance interest in paleopathological research among Chinese scholars, and to foster the use of differential diagnosis as the key mode of paleopathological analysis; and (3) to initiate integration of pathological analysis of human skeletal collections with historical records documenting early medical practices, epidemics, development and age-related diseases, and demographic records.

The collection of papers that follows present new data, from a range of time periods and geographic and social contexts, …


The Role Of Remediation In Library Reference, William Blick Mar 2020

The Role Of Remediation In Library Reference, William Blick

Publications and Research

While working at a fast paced reference desk at a busy community college, a librarian may encounter many challenging questions and situations. One such problem that may exist on a community college level is that of the very needy student, who not only has issues with information literacy, but with reading competency and computer literacy. The question is: “ on what on level is the librarian responsible for remediating the student in a the brief and confining limitations of the reference interview?” This paper seeks to explore the role of the librarian as he or she relates to remediation and …


Creating And Using Open Educational Resources (Oer) In Reading And Writing Classes, Christine E. Hutchins Mar 2020

Creating And Using Open Educational Resources (Oer) In Reading And Writing Classes, Christine E. Hutchins

Publications and Research

Creating her own assignments using openly licensed course materials allows this professor and her students to be more creative and to take greater advantage of digital resources.


Bella Figura: Understanding Italian Communication In Local And Transatlantic Contexts, Denise Scannell Guida Mar 2020

Bella Figura: Understanding Italian Communication In Local And Transatlantic Contexts, Denise Scannell Guida

Publications and Research

Bella figura—beautiful figure—is an idiomatic expression used to reflect every part of Italian life. The phrase appears in travel books and in transnational business guides to describe Italian customs, in sociological research to describe the national characteristics of Italians, and in popular culture to depict thematic constructs and stereotypes, such as the Mafia, romance, and la dolce vita. Scholarly research on bella figura indicates its significance in Italian civilization, yet it remains one of the most elusive concepts to translate. Among the various interpretations and references from foreigners and Italians there is not a single definition that captures the …


Work Alienation And Its Gravediggers: Social Class, Class Consciousness, And Activism, Jeremy Sawyer, Anup Gampa Feb 2020

Work Alienation And Its Gravediggers: Social Class, Class Consciousness, And Activism, Jeremy Sawyer, Anup Gampa

Publications and Research

Work activity is central to human psychology. However, working conditions under capitalist socioeconomic relations have been posited as psychologically alienating. Given the negative impact of work alienation on well-being and mental health, we conducted two studies of the relations between social class, work conditions, and alienation. We also examined factors that might counteract alienation – class consciousness and activism. The utility of a Marxist measure of social class – based on objective work relations – was compared with that of SES and subjective class measures. Study 1 surveyed 240 U.S. adults from diverse socioeconomic backgrounds using Amazon’s Mechanical Turk; Study …


The Public Reckoning: Anti-Debt Futures After #Rickyrenuncia, Sarah Molinari Feb 2020

The Public Reckoning: Anti-Debt Futures After #Rickyrenuncia, Sarah Molinari

Publications and Research

This essay argues that the summer 2019 mobilizations in Puerto Rico and the renewed demand for a debt audit help to imagine anti-debt futures that disrupt the terms and temporalities of public debt and indebted lives. The essay discusses one form of debt resistance-a comprehensive citizen debt audit-as central to deepen the process of public reckoning marked by #RickyRenuncia and to build upon the landscapes of protest and solidarity emerging in its wake.


Transposon Mutagenesis In Mycobacterium Kansasii Links A Small Rna Gene To Colony Morphology And Biofilm Formation And Identifies 9,885 Intragenic Insertions That Do Not Compromise Colony Outgrowth, William C. Budell, Gabrielle A. Germain, Niklas Janisch, Zaid Mckie-Krisberg, Anitha D. Jayaprakash, Andrew E. Resnick, Luis E. N. Quadri Feb 2020

Transposon Mutagenesis In Mycobacterium Kansasii Links A Small Rna Gene To Colony Morphology And Biofilm Formation And Identifies 9,885 Intragenic Insertions That Do Not Compromise Colony Outgrowth, William C. Budell, Gabrielle A. Germain, Niklas Janisch, Zaid Mckie-Krisberg, Anitha D. Jayaprakash, Andrew E. Resnick, Luis E. N. Quadri

Publications and Research

Mycobacterium kansasii (Mk) is a resilient opportunistic human pathogen that causes tuberculosis-like chronic pulmonary disease and mortality stemming from comorbidities and treatment failure. The standard treatment of Mk infections requires costly, long-term, multidrug courses with adverse side effects. The emergence of drug-resistant isolates further complicates the already challenging drug therapy regimens and threatens to compromise the future control of Mk infections. Despite the increasingly recognized global burden of Mk infections, the biology of this opportunistic pathogen remains essentially unexplored. In particular, studies reporting gene function or generation of defined mutants are scarce. Moreover, no transposon (Tn) mutagenesis tool has been …


Effects Of Speech Cues In French-Speaking Children With Dysarthria, Erika S. Levy, Gemma Moya-Galé, Younghwa Michelle Chang, Luca Campanelli, Andrea A. N. Macleod, Sergio Escorial, Christelle Maillart Feb 2020

Effects Of Speech Cues In French-Speaking Children With Dysarthria, Erika S. Levy, Gemma Moya-Galé, Younghwa Michelle Chang, Luca Campanelli, Andrea A. N. Macleod, Sergio Escorial, Christelle Maillart

Publications and Research

Background: Articulatory excursion and vocal intensity are reduced in many children with dysarthria due to cerebral palsy (CP), contributing to the children’s intelligibility deficits and negatively affecting their social participation. However, the effects of speech-treatment strategies for improving intelligibility in this population are understudied, especially for children who speak languages other than English. In a cueing study on English-speaking children with dysarthria, acoustic variables and intelligibility improved when the children were provided with cues aimed to increase articulatory excursion and vocal intensity. While French is among the top 20 most spoken languages in the world, dysarthria and its management in …


Proceedings Of The Cuny Games Conference 6.0, Robert O. Duncan, Joseph Bisz, Christina Boyle, Kathleen Offenholley, Maura A. Smale, Carolyn Stallard, Deborah Sturm Feb 2020

Proceedings Of The Cuny Games Conference 6.0, Robert O. Duncan, Joseph Bisz, Christina Boyle, Kathleen Offenholley, Maura A. Smale, Carolyn Stallard, Deborah Sturm

Publications and Research

The CUNY Games Network is an organization dedicated to encouraging research, scholarship and teaching in the developing field of games-based learning. We connect educators from every campus and discipline at CUNY and beyond who are interested in digital and non-digital games, simulations, and other forms of interactive teaching and inquiry-based learning. These proceedings summarize the CUNY Games Conference 6.0, where scholars shared research findings at a three-day event to promote and discuss game-based pedagogy in higher education. Presenters could share findings in oral presentations, posters, demos, or play testing sessions. The conference also included workshops on how to modify existing …


Daerim Dong As A Chinatown: Setbacks And Challenges, Wendy W. Tan Feb 2020

Daerim Dong As A Chinatown: Setbacks And Challenges, Wendy W. Tan

Publications and Research

While there is not a single Chinese paifang, or any establishment targeted for tourist attractions, Daerim Dong in Seoul, due to its high concentration of Chinese population and business activities, has been considered as an unofficial 2nd Korean Chinatown. However, at the same time, many indicators are also pointing to the discouraging fact that the path toward making this plan a reality is full of bumps. Why is this conflicting situation happening? To satisfy her own curiosity, the author did intensive literature research and also made a field trip to this district. This essay states some of her findings.


Raw Veganism: The Human Diet, Carlo Alvaro Feb 2020

Raw Veganism: The Human Diet, Carlo Alvaro

Publications and Research

In this chapter, I present some compelling evidence that points to the conclusion that the human species has a specific diet, which is a raw vegan diet of fresh fruit, tender leafy greens, and a moderate amount of nuts and seeds. Out of the hundreds of thousands of species in the world, the only one—ours—cooks food. Not surprisingly, our species is the only one that suffers from numerous maladies. In other words, the argument is that the consumption of cooked food (especially animal-based) is unhealthful and undermines our nature. I present undeniable evidence, from evolutionary science to nutrition science, showing …


Polymers For Extrusion‐Based 3d Printing Of Pharmaceuticals: A Holistic Materials–Process Perspective, Mohammad A. Azad, Deborah Olawuni, Georgia Kimbell, Abu Zayed Badruddoza, Md. Shahadat Hossain, Tasnim Sultana Feb 2020

Polymers For Extrusion‐Based 3d Printing Of Pharmaceuticals: A Holistic Materials–Process Perspective, Mohammad A. Azad, Deborah Olawuni, Georgia Kimbell, Abu Zayed Badruddoza, Md. Shahadat Hossain, Tasnim Sultana

Publications and Research

Three dimensional (3D) printing as an advanced manufacturing technology is progressing to be established in the pharmaceutical industry to overcome the traditional manufacturing regime of ʹone size fits for allʹ. Using 3D printing, it is possible to design and develop complex dosage forms that can be suitable for tuning drug release. Polymers are the key materials that are necessary for 3D printing. Among all 3D printing processes, extrusion‐based (both fused deposition modeling (FDM) and pressure‐assisted microsyringe (PAM)) 3D printing is well researched for pharmaceutical manufacturing. It is important to understand which polymers are suitable for extrusion‐based 3D printing of pharmaceuticals …


Evaluation Of Health Literacy And Depression Literacy Among Korean Americans, Kunsook Bernstein, Shinhi Han, Young-Me Lee, Oisaeng Hong Feb 2020

Evaluation Of Health Literacy And Depression Literacy Among Korean Americans, Kunsook Bernstein, Shinhi Han, Young-Me Lee, Oisaeng Hong

Publications and Research

Low health literacy is closely related to a higher rate of hospitalization and of emergency services usage, leading to billions of dollars in avoidable health care costs and contributing to individuals’ poor physical and mental health. While Korean Americans (KAs) have a high prevalence of general health and mental health problems, relatively little is known about their health and mental health literacy, specifically their depression literacy. This study aims to evaluate KAs’ health literacy and depression literacy, as related to sociodemographic characteristics. An exploratory study was conducted with 681 community-residing adult KAs using the Center for Epidemiologic Studies Depression (CES-D) …


Open To What? A Critical Evaluation Of Oer Efficacy Studies, Ian Mcdermott Feb 2020

Open To What? A Critical Evaluation Of Oer Efficacy Studies, Ian Mcdermott

Publications and Research

This selective literature review evaluates open educational resources (OER) efficacy studies through the lens of critical pedagogy. OER have radical potential as transformative tools for critical pedagogy or they can serve as a cost-free version of the status quo, inclined toward propagating austerity. This review analyzes studies published since 2008 with regard to cost, access, pedagogy, commercialization, and labor. These criteria are used to make explicit subjects indirectly addressed, if not ignored completely, in the existing literature. Typically, ample attention is paid to a study’s design and methodology but the underlying institutional infrastructure and decision-making process is unexamined. What emerges …


Recording Studios Since 1970, Eliot Bates Feb 2020

Recording Studios Since 1970, Eliot Bates

Publications and Research

Like many other specialty, purpose-built spaces, we tend to think of recording studios in instrumental terms, meaning that the space is defined in relation to the nominal type of work that the space is instrumental towards. While audio recordings have been made in spaces since 1877, not all of these spaces tend to be regarded as recording studios, partly since so many recordings were made in environments designed for other types of work; indeed, much of the first seventy years of US and UK recorded music history transpired at radio stations, concert halls and lightly treated mixed-use commercial spaces (e.g. …


Capitalism And The Immigrant Rights Movement In The United States, Marcel Paret, Sofya Aptekar, Shannon Gleeson Jan 2020

Capitalism And The Immigrant Rights Movement In The United States, Marcel Paret, Sofya Aptekar, Shannon Gleeson

Publications and Research

Social movements are full of contradictions, and an inherent tension often emerges between reformist and radical flanks. This becomes especially true as activists attempt to draw connections between varied aims such as opposition to globalization and support for immigrants. During the 1999 Battle of Seattle, the movement focused on opposing neoliberalism (Graeber 2002) and advocating for alternative visions of globalization (Reitan 2012). Some activists also noted the hypocrisy of opening borders to capital while militarizing the borders for migrants. Yet, in the end, immigrant rights movements and their central issues did not feature prominently in Seattle or later anti-globalization efforts. …


Supporting Institutional Objectives By Embedding Mission-Critical Competencies In Credit-Bearing Library Instruction: A Review And Case Study, Derek Stadler, Alexandra Rojas Jan 2020

Supporting Institutional Objectives By Embedding Mission-Critical Competencies In Credit-Bearing Library Instruction: A Review And Case Study, Derek Stadler, Alexandra Rojas

Publications and Research

This article reviews scholarship of incorporating institutional objectives in academic courses and proposes a method to embed mission-critical competencies in a library instruction course. Few academic institutions focus their mission or core competencies on digital communication. LaGuardia Community College delineates three competencies in its mission: inquiry and problem solving, global learning, and integrative learning. Students exhibit command of these competencies in written, oral, or digital communication. The College defines the digital communication ability as successful collaboration and interaction using online tools, such as discussion boards, either to stage written exchange, or to capture video or oral discussions. Through participation in …


I Was Called, Too: The Life And Work Of Coretta Scott King, Kristopher B. Burrell Jan 2020

I Was Called, Too: The Life And Work Of Coretta Scott King, Kristopher B. Burrell

Publications and Research

I thought it both appropriate—and overdue—to discuss the significance of Coretta Scott King. And not just as the wife, and eventual widow, of Martin Luther King; but as an important activist and shaper of Dr. King’s ideas. Mrs. King was a significant figure in her own right, but as with many female historical figures her historical importance has often been minimized or negated; and that can lead to erasure, even in plain sight. This has largely been the case with Mrs. King and with black women in the civil rights movement more broadly.


We Need A Loud And Fractious Poor, Jeff Maskovsky, Frances Fox Piven Jan 2020

We Need A Loud And Fractious Poor, Jeff Maskovsky, Frances Fox Piven

Publications and Research

This article explores the political consequences of four decades of consistent humiliation of the poor by the most authoritative voices in the land, and offers insights into ways that new movements are creating spaces for poor people’s political voices to surface and become relevant again. Our specific concern is the challenge that the current humiliation regime poses to those who seek to revive radical, disruptive and fractious anti-poverty activism and politics. By humiliation regime, we mean a form of political violence that maltreats those classified popularly and politically as “the poor” by treating them as undeserving of citizenship, rights, public …


Presence: Hope And 21st Century American Academia, Aaron Barlow Jan 2020

Presence: Hope And 21st Century American Academia, Aaron Barlow

Publications and Research

Observations on American higher education that first appeared as blog posts, these were sparked by the progress of the author's own academic career from adjunct to full professor, a progression that also included six years as the Faculty Editor of "Academe," the magazine of the American Association of University Professors.


In Vitro Evaluation Of The Influence Of Substrate Mechanics On Matrix-Assisted Human Chondrocyte Transplantation, Yueh-Hsun Kevin Yang, Courtney R. Ogando, Gilda A. Barabino Jan 2020

In Vitro Evaluation Of The Influence Of Substrate Mechanics On Matrix-Assisted Human Chondrocyte Transplantation, Yueh-Hsun Kevin Yang, Courtney R. Ogando, Gilda A. Barabino

Publications and Research

Matrix-assisted chondrocyte transplantation (MACT) is of great interest for the treatment of patients with cartilage lesions. However, the roles of the matrix properties in modulating cartilage tissue integration during MACT recovery have not been fully understood. The objective of this study was to uncover the effects of substrate mechanics on the integration of implanted chondrocyte-laden hydrogels with native cartilage tissues. To this end, agarose hydrogels with Young’s moduli ranging from 0.49 kPa (0.5%, w/v) to 23.08 kPa (10%) were prepared and incorporated into an in vitro human cartilage explant model. The hydrogel-cartilage composites were cultivated for up to 12 weeks …


The Tale Of Two Community Gardens: Green Aesthetics Versus Food Justice In The Big Apple, Sofya Aptekar, Justin S. Myers Jan 2020

The Tale Of Two Community Gardens: Green Aesthetics Versus Food Justice In The Big Apple, Sofya Aptekar, Justin S. Myers

Publications and Research

There has been a vibrant community gardening movement in New York City since the 1970s. The movement is predominantly located in working class communities of color and has fought for decades to turn vacant land into beneficial community spaces. However, many of these communities are struggling with gentrification, which has the potential to transform access to and use of community gardens in the city and the politics around them. Drawing on separate multi-year ethnographic projects, this article compares two community gardens in food insecure communities in Queens and Brooklyn: one that is undergoing gentrification and one that is not. We …


Excavating A Future Vision Past: Mike Davis’ City Of Quartz, William Blick Jan 2020

Excavating A Future Vision Past: Mike Davis’ City Of Quartz, William Blick

Publications and Research

When Mike Davis published City of Quartz in 1990, his work was widely praised by many and dismissed as liberalist hysteria by others. The reflections it contains on architectural design as a reflection of sociopolitical tumult still strike chords today. This article sets out a reexamination of the text through hindsight, using contemporary and subsequent reviews to consider how the book was relevant at the time of its publication, how it may be relevant today and how it has had a profound impact on sociological and cultural studies.


Standard Language Ideology Is Alive And Well In Public Speaking Textbooks, Carlos De Cuba, Poppy Slocum Jan 2020

Standard Language Ideology Is Alive And Well In Public Speaking Textbooks, Carlos De Cuba, Poppy Slocum

Publications and Research

For more than 50 years, the field of linguistics has recognized the equality of human languages, including all dialects of all languages. In this study we examine how current popular public speaking textbooks handle issues of linguistic variation in English. We looked specifically at textbook discussions of accent, grammar and pronunciation. Unfortunately, we have found the majority of textbooks we examined serve to maintain the outdated “deficit” model of language variation, to the detriment of students.


Water In Your Neighbourhood: A Model For Implementing A Semester-Long Course-Based Undergraduate Research Project In Introductory Biology, Ana Lucia Fuentes, Maria Entezari Jan 2020

Water In Your Neighbourhood: A Model For Implementing A Semester-Long Course-Based Undergraduate Research Project In Introductory Biology, Ana Lucia Fuentes, Maria Entezari

Publications and Research

Undergraduate biology education has changed over the past decade, incorporating an iterative and evidence-based approach. Many educational assessments have confirmed the effectiveness of integrating authentic research and open-ended inquiry into introductory biology courses, demonstrating a significant positive impact on students’ learning and attitude towards STEM majors. Despite these findings, only a handful of Biology instructors in 2-year colleges adopt this approach, and when adopted, most activities constitute a small fraction of these courses. Finding a feasible, sustainable, semester-long, and cost-effective strategy to incorporate authentic research in the curriculum which promotes integrated understanding of science and addresses socio-scientific issues, is a …


Cis-Regulatory Analysis Of Onecut1 Expression In Fate-Restricted Retinal Progenitor Cells, Sruti Patoori, Nathalie Jean-Charles, Ariana Gopal, Sacha Sulaiman, Sneha Gopal, Brian Wang, Benjamin Souferi, Mark Emerson Jan 2020

Cis-Regulatory Analysis Of Onecut1 Expression In Fate-Restricted Retinal Progenitor Cells, Sruti Patoori, Nathalie Jean-Charles, Ariana Gopal, Sacha Sulaiman, Sneha Gopal, Brian Wang, Benjamin Souferi, Mark Emerson

Publications and Research

Background: The vertebrate retina consists of six major classes of neuronal cells. During development, these cells are generated from a pool of multipotent retinal progenitor cells (RPCs) that express the gene Vsx2. Fate-restricted RPCs have recently been identified, with limited mitotic potential and cell fate possibilities compared to multipotent RPCs. One population of fate-restricted RPCs, marked by activity of the regulatory element ThrbCRM1, gives rise to both cone photoreceptors and horizontal cells. These cells do not express Vsx2, but co-express the transcription factors (TFs) Onecut1 and Otx2, which bind to ThrbCRM1. The components of the gene regulatory networks that control …